Taiwan - Biotech Companies - Career Pages
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
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Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Vicus Therapeutics | , | Gone 2019 |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| Acumed | Beijing, China | Medical Implants |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Boragen | , | Renamed Reactive Biosciences |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Large Scale Biology | , | Shut Down |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
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Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| Sanovel | Istanbul, Turkey | Generics |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| LyoGo | , | Website gone, all employees gone |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
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Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| Proxygen | Vienna, Austria | Cancer Therapies |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Zars Pharma | , | Acquired by NuVo Research |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Procos | Cameri, Italy | Contract Manufacturing |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| SVBio | , | Changed name to Lifecode |
| , | Website taken over Feb 2026 | |
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Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Tecomet | Riviera Beach, FL | CNC Machining, EDM, Special Processes |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| , | Renamed Verge Medical, Mar 2025 | |
| myoscience | , | Renamed iovera |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| LianBio | , | Winding down Feb 2024 |
| AngioCure | , | Employees all gone, Nov 2017 |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| US Genomics | , | Now PathoGenetix |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| , | Shut down Jan 2026 | |
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Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| Tangent Medical Systems | , | Closed |
| Evolve BioSystems | , | Renamed Infinant Health |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Progenika | , | Bought by Grifols |
| Texcell | Shanghai, China | Contract Research |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
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Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Adynxx | , | Website taken over Sep 2020 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Gangagen | Bangalore , India | Ectolysins |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| Multerra Bio | , | Bankrupt May 2021 |
| Ergomed | Krakow, Poland | Clinical Research |
| Sanofi | Haverhill, UK | Small Molecules |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| NeoVentures | London, ON | Custom Aptamers |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
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Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| Stada | Bad Vilbel, Germany | Generics |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
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Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Pinnaxis | Noida, India | Pharmacovigilance |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Hovione | Macau, China | Contract Manufacturing |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| In Veritas Medical Diagnostics | , | Shell company |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
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Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Analog Pharma | Princeton, NJ | Generics |
| SuraMedical | , | Most employees left, not registered in MN |
| Biotrofix | , | Gone, Dec 2014 |
| Endocare | , | Website down Jan 2021 - May 2021 |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| , | Now a Genovis product/service, Jul 2026 | |
| ClearView | Newton, MA | Strategic Consulting |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| Saghmos Therapeutics | , | |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Codon Devices | , | Closed Apr 2009 |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| Copley Scientific | Nottingham, UK | Test equipment |
| Envision Pharma | , | Merged with UBC |
| AuraSense Therapeutics | , | Renamed Exicure |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Navigenics | , | Acquired by Life Technologies 2012 |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Instapath | Houston , TX | Automated Digital Pathology |
| Cell Biosciences | , | Now ProteinSimple |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| BioMap | Palo Alto, CA | AI Models |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| , | Main employees gone for months as of Nov 2025 | |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
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Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Recodagen | , | Gone Jun 2009 |
| bioMerieux | Lombard, IL | Diagnostics |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| GliaGen | , | Renamed CaCy Therapeutics |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| , | Renamed Fareon, Feb 2025 | |
| , | Renamed First Atom Therapeutics | |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Niagara Biosciences | , | No info, Aug 2022 |
| Sitka Biopharma | , | Website gone Jan 2022 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| Axplora | Raubling, Germany | API CDMO |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| NuAire | Plymouth, MN | Lab Equipment |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| MicroCam | , | Shut down 2015? |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| , | Website down Jul 2025 - Dec 2025 | |
| Jade Biosciences | Virtual, US | Biologics for Autoimmune Diseases |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| TRPblue | , | Shut down Dec 2023 |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Dharma Therapeutics | , | Gone, 2013 |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| Transave | , | Merged with Insmed Dec 2010 |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| EhmetDx | , | Renamed Ehmet Health |
| Innexus Biotechnology | , | Gone |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Kentucky Bioprocessing | , | Now Kbio |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| Pharma Medica | Mississauga, ON | Clinical Services |
| , | Acquired by Instem, Jul 2025 | |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| RegeneMed | , | No longer active in CA as of 2014 |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Trek Therapeutics | , | Shut down Sep 2019 |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Norgine | Vienna, Austria | Specialty Pharma |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Alnis BioSciences | , | No info |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| GenSensor | Nantes, France | Process Analytical Technology |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| Brighton Biotech | , | Only employee is an accountant |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| , | Shut down Mar 2026 | |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| TaliaPharm | , | Website gone, Jan 2018 |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| Apotex | Toronto, ON | Small Molecule Generics |
| Antibiotice | Iasi, Romania | Generics |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| ALTx Therapeutics | , | Small Molecule Therapies |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Medtronic | Danvers, MA | Medical Devices |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| Quartzy | Hayward, CA | Lab Management Software |
| , | Shut down late 2025 | |
| Sopharma | Sofia, Bulgaria | Generics |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| Vascular Technology | Nashua, NH | Surgical Devices |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Elite Research Institute | , | Gone, May 2018 |
| T-Ray Science | , | Renamed Verisante |
| Instil Bio | Dallas, TX | Cell Therapy |
| Silence Therapeutics | Berlin, Germany | RNAi |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Balboa Biosciences | , | Gone 2010 |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| CSL Behring | Bradley, IL | Biologics |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Advanz Pharma | London, UK | Specialty Generics |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| , | Website down Jan 2026 - Apr 2026 | |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| Amphora Medical | , | Shut down May 2019 |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| , | Website under construction Dec 2024 - May 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
 |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Dec 2025 - Jun 2026 | |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Vanguard Therapeutics | , | |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| Agile EndoSurgery | , | Gone |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Roche | Laval, QC | Diagnostics |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Validation Associates | Herndon, VA | Validation Consulting |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Santen | Emeryville, CA | Ophthalmics |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| Parabase Genomics | , | Presumed gone |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
 |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Cytheris | , | Out of business 2013 |
| , | Assets moved to Co-Diagnostics, 2013 | |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Ativa Medical | , | Renamed Immune IQ? |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| Ribomic | Tokyo , Japan | Aptamers |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| Vivid Genomics | , | Shut down Sep 2023 |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| EmpowerPharm | , | Shut down |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| , | Shut down Dec 2023 | |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| LifeMax | , | Part of AmMax |
| CeQur | Luzern, Switzerland | Insulin pump |
| Biotrin International | , | Renamed Diasorin? |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Nya Cell Therapeutics | , | No info |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| Virtici | Seattle, WA | Product / Company Incubator |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Coley Pharma | , | Acquired by Pfizer |
| ActivaTek | , | Acquired by North Coast Medical |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Helsinn | Dublin, Ireland | Small Molecules |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| , | Renamed Cyllene Therapeutics, Jul 2026 | |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| TandemAI | New York, NY | AI to democratize the drug development process |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Capsigen | Vancouver, WA | AAV Vectors |
| Clinical Microbiomics | , | Merged into cmbio |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Dornier MedTech | Sillingy, France | Urology Devices |
| Ocis Biotechnology | , | |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Alliqua | Langhorne, PA | Hydrogels |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| Endovasc | , | Bankrupt 2008 |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
 |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Ebewe Pharma | , | Now Sandoz |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| APIE Therapeutics | , | Gone Jun 2025 |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| AxoGlia Therapeutics | , | Ran out of money |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Getinge | Fairfield , NJ | Medical Technology |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| SFS | Madrid, Spain | Clinical Research Organization |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
 |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Artera | Los Altos, CA | AI Diagnostics |
| Ataia Medical | , | Website taken over Jan 2024 |
| Molsid | Lyon, France | Fluorogenic Probes |
| Vascular Biogenics | , | Now VBL Therapeutics |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Allux Medical | , | Shut down, Feb 2009 |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| Theravance Biopharma | South SF, CA | Small Molecules |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| LynxDx | Ann Arbor, MI | Diagnostics |
| MDQuest | , | Website Down Feb 2025 |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Singular Genomics | San Diego, CA | Genomics |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Formation Biologics | , | Rebranded as Forbius |
| , | Website down Nov 2025 - Apr 2026 | |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| , | Assets Acquired by Klotho, Sep 2025 | |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| Beacle | , | Founder gone, no info |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Tapestry Pharmaceuticals | , | Gone |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| MSM Protein Technologies | , | Gone Jun 2019 |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Carrington Labs | , | Changed Name to DelSite |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Angex Pharmaceuticals | , | Gone 2018 |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Brightflow Medical | Paris, France | Heart Failure Device |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Cibiem | , | Shut down May 2021 |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Monroe Research | Monroe, NC | Clinical Trials |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| Expression Patholgy | , | Now OncoPlexDx |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| LC Technologies | , | Renamed EyeGaze |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| ProteinLinks | , | Seem gone |
| Aixa Bio | Cambridge, MA | AI genomics |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| LENSAR | Orlando, FL | Cataract Laser |
| SynAm Vaccine | , | Gone 2017 |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| AbbVie | Dublin, Ireland | Medical Devices |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Bionas Discovery | , | Website gone Jun 2018 |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Molecular Logix | , | Gone, Dec 2018 |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Amakem | , | Website gone Dec 2015 |
| Hovione | Mumbai, India | Contract Manufacturing |
| Existence Genetics | , | Bankrupt Dec 2012 |
| Bayer | Mailand , Italy | Small Molecules |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Genfit | Cambridge, MA | Drug Discovery |
| Stryker | Mahwah, NJ | Medical Devices |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| Kasocio | , | Liquidated, Dec 2019 |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| G6 Spine | , | Gone 2017 |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Synfini | Menlo Park, CA | AI Drug Design |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Envision Genomics | , | Website gone Nov 2019 |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| NexMed | , | Now Apricus Bio |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| Innovagen | Lund, Sweden | Custom antibody development |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| ViThera Pharmaceuticals | , | Gone 2017 |
| iBio | San Diego, CA | Antibody Therapies |
| , | Merged with Cohance, May 2025 | |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Sebia | Lisses, France | Electrophoresis |
| Epic Sciences | , | Shut down May 2025 |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Createrna Science | Wuhan, China | Small Molecules |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Anfiro | , | Shut down Dec 2019 |
| Apnex Medical | , | Shut down, Aug 2013 |
| SeqRight | , | Acquired by GE Apr 2012 |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Catalina Pharma | , | No info 2017-2022 |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| , | Website down Sep 2025 - Dec 2025 | |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Sharp | Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| Streamline Scientific | Austin, TX | Molecular Technologies |
| Cellnovo | , | Bankrupt, Jul 2019 |
| VaxInnate | , | Dissolved Feb 2017 |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| BioChain | Newark, CA | Sample Preparation |
| STARLIMS | Hollywood, FL | LIMS |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Ipsen | Wrexham, UK | Biologics |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Ignis Therapeutics | Shanghai, China | |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| Five Star Products | , | Liquidated |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
 |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Tempered Biosciences | , | Absurd website has to be gone |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Ergomed | Geneva, Switzerland | Clinical Research |
| Epigenos Biosciences | , | |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| |
Cheshire, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Alibion | , | Website down May 2021 - Sep 2021 |
| DNA Worldwide | Frome, UK | DNA Testing |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Venta Medical | , | Gone, Apr 2017 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| , | Website taken over May 2026 | |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| Cytoskeleton | Denver, CO | Research Products |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
 |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| BGI | Copenhagen, Denmark | Diagnostics |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Baxter | Deerfield, IL | Medication Delivery |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Bioptimus | Paris, France | AI Drug Discovery |
| Forge Biologics | Grove City, OH | Biologics |
| Attogene | Austin, TX | Rapid Diagnostics |
| IvWatch | Newport News, VA | IV infiltration detection |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| , | Website down Sep 2025 - Jan 2026 | |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Anazen Diagnostics | , | Part of Cardiox |
| Haemonetics | Boston, MA | Blood Management Solutions |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| ArgusEye | Linköping, Sweden | Biosensors |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| X2 Pharma | , | Website Gone |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| DecImmune Therapeutics | , | Gone 2017 |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| , | Renamed BTgen Bio, May 2026 | |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| PPD | Middleton, WI | Contract R & D, Consulting |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Occam Design | Louisville, SS | Medical Device Development |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| LivaNova | London, UK | Nerve stimulation therapy |
| Cytera CellWorks | , | Renamed Mytos |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| Revolution Biomanufacturing | Worcester, MA | mRNA, lipid nanoparticle CDMO |
| Califia Bio | , | Shut down May 2020 |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| , | Renamed Ribonexus, Nov 2021 | |
| Acylin Therapeutics | , | Assets sold 2014 |
| NsGene | , | Website gone |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| NantCell | , | Renamed ImmunityBio |
| Profluent | Emeryville, CA | AI Protein Creation |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| Advansta | San Jose, CA | Protein characterization products |
| , | Dissolved, Apr 2024 | |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Hemaquest | , | Gone by 2017, No info |
| Corza Medical | Somerset, UK | Surgical Devices |
| Getinge | Hechingen, Germany | Medical Technology |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Evocutis | , | Pivoted to investments |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| BioArctic | Stockholm, Sweden | CNS treatments |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Customized Therapeutics | , | Business Lapsed 2011 |
| ResearchDx | Irvine, CA | Diagnostics |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Cytecs | Münster, Germany | Cell Analysis |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| BioRelix | , | Restructured. Unknown Status. |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| OmniGuide | Billerica, MA | Surgical technology |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| Tecomet | Holt, MI | Additive Manufacturing, Forging - Orthopedics |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Agilent | Longmont, CO | High-Throughput Screening Equipment, Imaging instruments |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Odyssey Thera | , | Shut down 2014 |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| Osteolab | , | Spam site |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Bluestar Genomics | , | Renamed ClearNote Health |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| , | Renamed Aurevia | |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| Ikano Therapeutics | , | Gone |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| PLC Medical Systems | , | Renamed RenalGuard |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| SJ Pharma | , | Website gone, Nov 2018 |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| MicroVention | , | Now Terumo Neuro |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| Niveus Medical | , | Closed Dec 2017 |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Appili Therapeutics | Halifax, NS | Small molecule |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| Metrohm | Riverview, FL | Lab Data Management Software |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| TamuroBio | , | Shut Down Jun 2024 |
| JD Bioscience | Seoul, Korea | Small Molecules |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| , | Shut down Oct 2024 | |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Esculon | , | Seems defunct, employees gone |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| Micrologix Biotech | , | Renamed Migenix |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| Fortrea | Durham, NC | Clinical Research |
| nitec Pharma | , | Merged with Horizon Pharma |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| Eminent Services | Frederick, MD | Drug Services |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Avenir Pharma | , | No longer active |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| SuperX | , | Gone |
| Cellink | Kyoto, Japan | Bioprinting |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Parexel | Sheffield, UK | Clinical Research |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Cogenics | , | Now Beckman Coulter Genomics |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Cherry Biotech | Paris, France | Organoid Culture |
| Lupin | Coral Springs, FL | Generics |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| , | Website down Oct 2025 - Dec 2025 | |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Nexus Genomics | , | Gone 2001 |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Website down Aug 2025 - Jan 2026 | |
| Meissner | Camarillo, CA | Lab Systems |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| NovaDel Pharma | , | Business dissolved 2014 |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
 |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Indero | Montréal, QC | Dermatology Clinical Research |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| Creative Enzymes | Shirley, NY | Enzymes |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| , | Website down Jan 2026 - May 2026 | |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Cryoniss | Deeside, UK | Bio Banking |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Lindus Health | London, UK | CRO |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Baxter | Singapore, Singapore | Medication Delivery |
| Indexus Biomedical | , | Shut down 2018 |
| Koelis | Meylan, France | Prostate Biopsy System |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| PDL BioPharma | , | Shut down early 2021 |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| ProPharma Group | Bozeman, MT | Consulting |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Trilations | New York, NY | Strategic Consulting |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Celvive | , | No news from 2012-2020 |
| Xcede Technologies | , | Gone Jun 2020 |
| CureBiotech | , | Presumed gone |
| XtalPi | Shenzhen, China | AI Drug Design |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| GIPAM | Wismar, Germany | Market Access Consulting |
| TcLand Expression | , | Website Gone |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| EmpathBio | , | |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Veeva Systems | Radnor, PA | Life Science Software |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Averion | , | Now Aptiv |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Heritage Pharmaceuticals | , | Part of Emcure |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| OSI Pharmaceuticals | , | Bought by Astellas |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Medelis | Ypres, Belgium | Clinical Research |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Institute for Drug Discovery | , | Gone |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Summit Therapeutics | Palo Alto, CA | Utrophin modulation technology |
| , | Renamed PICO BioScience, Jun 2026 | |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Axplora | Chennai, India | API manufacturing |
| Blackfynn | , | Gone Apr 2022 |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Genera Medix | , | Apparently sold all products |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| LuBioScience | Zürich, Switzerland | Lab products and services |
 |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| Formycon | Martinsried, Germany | Biosimilars |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| Apcer Life Sciences | London, UK | Consultants |
| Stada | Vršac, Serbia | Generics |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Bioneeds | Bangalore , India | Contract Research |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Tecomet | Warsaw, IN | Finishing, CNC Machining, Additive Manufacturing, Grinding |
| Light Sciences Oncology | , | Shut down late 2020 |
| Intellikine | , | Bought by Millennium 2011 |
| , | Shut down Jan 2024 | |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| Tecomet | Bristol, PA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Quanticate | Hitchin, UK | Clinical Research |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| TME Pharma | Berlin, Germany | L-aptamers |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| Acculysis | , | Website gone, sole employee with Agilent now |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Grunenthal | Origgio, Italy | Small molecules |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| LumaBridge | San Antonio, TX | Clinical Research |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Leading Pharma | Fairfield, NJ | Generics |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| QT Vascular | , | Website gone Jan 2024 |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Optherion | , | Sold Assets, Still Exists |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| NeuMed | , | Website four years since update, no employees on LI |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Kona Medical | , | Closed, Dec 2016 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| TearScience | , | Acquired by J&J, Nov 2017 |
| , | Shut down Oct 2024 | |
| , | Renamed aMBR Genomics, Jun 2026 | |
| VasoRx | San Diego, CA | RNA delivery |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Clinnex | Ahmedabad, India | Clinical Research |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| Bolder Biotechnology | Boulder, CO | Biologics |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Embecta | Parsippany, NJ | Diabetes Care |
| Appia Bio | , | Shut down Aug 2025 |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| Oxis International | , | Renamed GT Biopharma |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| AB Sciex | , | Renamed Sciex |
| , | Renamed Allotera Therapeutics, Jul 2026 | |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| , | Renamed FocalOne, Feb 2026 | |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Pirche | Grünwald, Germany | Transplant Matching |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Axonia Medical | , | Gone 2015 |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Singer Instruments | Watchet, UK | Laboratory automation |
| NeuroWave Systems | Beachwood, OH | EEG |
| Molecular Throughput | , | Rebranded as mtibio |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| , | Shut down Oct 2023 | |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| , | Shut down Apr 2026 | |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| MakroCare | San Francisco, CA | Drug Development Partner |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| Mabcare Therapeutics | , | |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| AbX Biologics | , | Renamed Abveris |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| , | Linkedin gone Jul 2026; Website down Mar 2026 - Jul 2026; Not positive on drug types | |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Karius | Redwood City, CA | Diagnostics |
| Interdict | San Francisco, CA | Small Molecules |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Advanced Vision Science | , | |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| Doctor Pack | Bangalore, India | Packaging |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| APSciences | , | Website gone Aug 2022 |
| Simpirica Spine | , | Became Empirical Spine |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| Alan Laboratories | , | Website gone, Jan 2019 |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| OriMAbs | , | Gone post 2022 |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| , | No news 2016 - Sep 2025 | |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| Promedior | , | Acquired by Roche, Feb 2020 |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| QuatRx | , | Acquired by Shionogi, 2017 |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Cetero Research | , | Renamed PRACS Institute |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| One Drop | , | Gone Dec 2024 |
| Liposonix | , | Bought by Medicis |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| Viravaxx | , | |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| NIOX | Uppsala, Sweden | Asthma management device |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| CultureTrax | , | Shut Down Dec 2019 |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| , | Acquired by AstraZeneca, Dec 2025 | |
| , | Now Nexus Spine | |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| ACROBiosystems | Zug, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Steba Biotech | , | Renamed ImPact Biotech |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| MeiRui Pharma | , | Bought by GSK |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| MJ Biopharma | Mumbai, India | Generics |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Accellacare | Hickory, NC | Clinical Research |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Elixir Pharmaceuticals | , | Gone |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Emmes | Rockville, MD | Clinical Research Organization |
| Evofem Biosciences | San Diego, CA | Women's health |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| CytoVera | , | Gone June 2017 |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| Spine View | , | Gone |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Nymirum | , | Renamed Base4, Feb 2023 |
| IQVIA | San Diego, CA | Clinical Research |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Medtronic | Minneapolis, MN | Medical Devices |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| , | Renamed Until Labs, Oct 2025 | |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Spyryx Biosciences | , | Shut down 2019 |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Cam Med | , | Renamed Qlibrium |
| , | Website down Feb 2026 - Jul 2026 | |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Mylan | , | Merged with Upjohn, renamed Viatris |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| ExThera Medical | Martinez, CA | Blood filtration |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| AmplifyBio | , | Shut down Apr 2025 |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| Quartet Medicine | , | Wound down, Nov 2017 |
| Bioenza | , | Website gone Sep 2017 |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| , | Website down Sep 2025 - Feb 2026 | |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| MacroPore | , | Gone |
| Biolab | Mississauga, ON | Small Molecules |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Oncorus | , | Liquidated, Jun 2023 |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Stasys Medical | , | Shut down Feb 2025 |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| , | Renamed Silthera, Apr 2026 | |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Fonar | Melville, NY | Upright MRI |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Getinge | Merrimack, NH | Medical Technology |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Rezolute | Bend, OR | Biologics |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| , | Acquired by Takara Bio, Jan 2025 | |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| GemoPharm | , | No news 2017-2022 |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| , | Renamed Athens Bioscience, Mar 2026 | |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| , | Linkedin gone Jul 2026; Website down Jun 2026 - Jul 2026; Cyrus Biotechnology spinout | |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Reach Separations | Nottingham, UK | Purification Services |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| Evoke Medical | , | Renamed DirectSync Surgical |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
 |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| Aikium | Berkeley, CA | AI Drug Discovery |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| Core Dynamics | , | Gone |
| Maccine | , | Gone |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| Vante BioPharm | , | Rebranded at Sebra |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| InfraReDx | Bedford , MA | Medical Devices |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Lupin | Somerset, NJ | Generics |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Endologix | Irvine, CA | Medical Devices |
| Keenova | Hazelwood, MO | Small Molecules |
| Diversa | , | Merged with Celunol to become Verenium |
| , | Gone Jul 2026, portions acquired by Axol Bioscience | |
| Mousera | , | Renamed Vium |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| DSG | Blue Bell, PA | Clinical Trial Software |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| CMP Pharma | Farmville, NC | Small Molecules |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| , | Website down Dec 2025 - Jun 2026 | |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| ImmuVen | , | Website gone, Dec 2015 |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| , | Shut down Jul 2014 | |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| Piramal | Aurora, ON | CDMO |
| , | Shutdown Oct 2025 | |
| |
Verona, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Formulatrix | Bedford, MA | Lab Automation |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Accellacare | Raleigh, NC | Clinical Research |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| Staburo | Munich, Germany | Clinical Services |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| FluoroPharma | , | Shell Company |
| Peplin | , | Acquired by Leo Pharma 2009 |
| , | Shut down Feb 2026 | |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| , | Website down Dec 2025 - Apr 2026 | |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| ParinGenix | , | Gone, 2012? |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Genfit | Loos, France | Drug Discovery |
| Apicore | Gujarat, India | API Development & Manufacturing |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| Diploid Genomics | , | |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| MedShape | , | Acquired by DJO, Apr 2021 |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| , | Website down Jul 2025 - Dec 2025 | |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Trophea | , | Liquidated, Dec 2019 |
| Alcon | Mississauga, ON | Eye Care Products |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Conformis | , | |
| Translational Bioscience | , | |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Cobalis | , | Basically Bust |
| Apollomics | Xiaoshan, China | Cancer medicines |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| Biomoles | , | Closed Sep 2017 |
| Avrin | Liverpool, UK | Clinical Research |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Alphatec Spine | , | Renamed Atec Spine |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| ChondroGene | , | Now GeneNews |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Piramal | Riverview, MI | CDMO |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Putney | , | Acquired by Dechra, Mar 2016 |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Trillium Diagnostics | , | Closed Jul 2016 |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| , | Acquired by Eclipsebio, Jan 2026 | |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| Remora Therapeutics | , | Shut down 2021 |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| seqWell | Beverly, MA | Sequencing Service |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| Celsis | , | Now AAIPharma |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| Oticon | Smørum, Denmark | Hearing Aids |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| , | No news 2021 - Sep 2025 | |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Compass Biotech | , | Defunct |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| , | Seems to have shut down mid 2025 | |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| Proteom | , | Acquired by Amura Ltd |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| , | Website down Dec 2025 - Apr 2026 | |
| RJS Biologics | , | Shut down Feb 2019 |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| ATON | Shanghai, China | CDMO |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| Abviva | , | Gone, 2008 |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| Soletics | , | Website gone Jun 2021 |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| Soluble Systems | , | Renamed Solsys Medical |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Ketal Biomedical | , | Gone |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| Medtronic | Shoreview, MN | Medical Devices |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Elektrofi | Boston, MA | Biologics Formulation |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| , | Acquired by Arterex, Jun 2023 | |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Genecure | , | Shut down Sep 2021 |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Statera Therapeutics | , | Shut down Jan 2022 |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Cellipse | , | Website taken over May 2020 |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Modular Bioscience | , | Seems gone Jun 2022 |
| , | Website down Dec 2025 - Apr 2026 | |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| Instylla | Bedford, MA | Embolization treatment |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Gilead | Oceanside, CA | Small Molecules |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
 |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| Micell Technologies | , | Seems shut down 2019 |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Cygene Labs | , | Gone |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Chromocyte | , | |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| Ufovax | , | Renamed Uvax Bio? |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| TamRx | , | Website taken over Aug 2020 |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| , | Renamed Edding, Feb 2026 | |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| Mitokyne | , | Renamed Mitobridge |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Siga | Corvallis, OR | Small Molecules |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| 3DBiopsy | , | Renamed Triopsy |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| Martek Biosciences | , | Bought by DSM |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| Innomab | , | Gone 2017 |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| SaluMedica | , | Website Gone Jul 2015 |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| Encorium | , | Bankrupt |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| Immagene | , | Renamed Flindr Therapeutics |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Cambrian Genomics | , | Shut down Dec 2017 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| , | Website down Jan 2026 - Mar 2026 | |
| Genemod | Edmonds, WA | Lab management software |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| TRIFARMA | Chennai, India | APIs |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Sunho Biologics | Nanjing, China | Biologics |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| Stryker | San Jose, CA | Medical Devices |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| Gene Sciences | , | Shut Down Jul 2019 |
| , | Acquired by Xoma, Sep 2025 | |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Prokarium | London, UK | Oral Vaccines |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| Chanelle Pharma | London, UK | Generics |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
 |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Aspira Labs | , | Renamed Aspira Women's Health |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Streamline Scientific | Birmingham, AL | Molecular Technologies |
| Recopharma | , | Seems gone |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| CytRx | , | Renamed LadRx Sep 2022 |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| EVerZom | Paris, France | Exosome Therapeutics |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| BGI | Hong Kong, China | Genetic Testing |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Cholestech | , | Now Alere |
| Evozyne | Chicago, IL | Protein Design Platform |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Filings late Jul 2022 - Jun 2026 | |
| AN2 Therapeutics | Menlo Park, CA | Boron-based medicines targeting infectious diseases |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Quanticate | Raleigh, NC | Clinical Research |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| CardioCanary | , | Founders gone. Doubt it's active |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| , | No news 2018 - Sep 2025 | |
| Phoresa | , | Shut down Mar 2018 |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| , | Acquired by Merck, May 2026, $6.67B | |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Thermo Fisher | Bend, OR | CDMO |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| , | Renamed Streamline Scientific | |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Ionian Technologies | , | Gone Mar 2016 |
| Nensius Research | , | Website Gone |
| Synovex | , | Renamed Adheron Therapeutics |
| MiniMed | Northridge, CA | Diabetes Management |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| Laureate Pharma | , | Acquired by Gallus |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| InteguRx | , | Website taken over, Dec 2023 |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| , | Renamed Aspen Neuroscience | |
| Mederi Therapeutics | , | Now Mederi-RF |
| CardioEphEx | , | Shut down Dec 2020 |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| , | Subsumed into Synoptics | |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| MetaMorphix | , | Changed to Scidera Genomics |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Pfizer | Ringaskiddy, Ireland | API production |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| BianoGMP | Gera, Germany | Oligonucleotides |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Opis Research | Desio, Italy | Clinical Research |
| Resprotect | , | No update since 2012 as of 2020 |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| Proimmune | Oxford, UK | Immunology research products |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Amivas | Waterford, Ireland | Antimalarial |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| Redpoint Research | , | Gone 2019 |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Alvea | , | Shut down Oct 2023 |
| Combs Lab | , | Website gone Dec 2016 |
| Inventiva | Daix, France | Small Molecules |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Genuiti Therapeutics | , | |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Seneb Biosciences | , | Gone 2017 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Nuvation Bio | New York, NY | Oncology Treatments |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| Syantra | Calgary, AB | Breast cancer blood test |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Northway Biotech | Waltham, MA | Contract research |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| McGee Pharma | , | Merged with Pharmalex |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| Osteologix | , | Liquidated, Sep 2015 |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Neurokos | , | Gone. No info |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Gene Techno Science | , | Renamed Kidswell Bio |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| CONMED | Largo, FL | Surgical, Medical Devices |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| , | Liquidated 2024 | |
| Novometrics | , | Dissolved Dec 2019 |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| MSD | Brinny, Ireland | Small Molecules |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| PrognosDx Health | , | Website gone Jun 2016 |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| DyNAbind | , | Shut down Apr 2025 |
| G1 Therapeutics | , | |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| TumorEnd | , | Website gone Feb 2019 |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Vivifi Life Sciences | Bangalore, India | Generics |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| , | Website down Oct 2025 - Feb 2026 | |
| Allergenics Inc | , | Closed Mar 2007 |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| , | Acquired by Vaxanix, May 2024 | |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| Indomo | Virtual, US | Acne Treatment |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| SteriTech | Sligo, Ireland | Process Equipment |
| , | Renamed Pixl.bio, Nov 2025 | |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Neurologix | , | Bankrupt, Liquidation |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Wacker | Amsterdam, Netherlands | Biologics CDMO |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| , | Website down Feb 2026 - Jul 2026 | |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Kembiotix | , | No info, Aug 2022 |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| , | Renamed WallabyPhenox | |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| , | Website down Jul 2025 - Dec 2025 | |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| PTM BioLabs | , | Renamed PTM BIO |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| GlycoSolutions | , | Closed Aug 2015 |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Parexel | Durham, NC | Clinical Research |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| AdrenaCard | , | Gone 2019 |
| Glen Research | Sterling, VA | Oligos |
| , | Website down May 2026 - Jul 2026; LI gone Jul 2026 | |
| Nuventra Pharma Sciences | , | Now Allucent |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| SunMed | , | Renamed AirLife |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Provasculon | , | Website Gone, Apr 2014 |
| Coferon | , | Renamed BlinkBio |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
 |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| Savage Medical | , | Renamed Averto Medical |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| LifeQual Pharmaceuticals | , | Website Gone |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Mustang Bio | Worcester, MA | Immunotherapies |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Doer Biologics | Hangzhou, China | Biologics |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| , | Shut down Nov 2025, Tempus acquired assets | |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Enovalife | Paris, France | Biometrics and medical writing services |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Getinge | Suzhou, China | Medical Technology |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Immunosyn | , | Charged with Securities Fraud |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| , | Website, Linkedin gone Jul 2026; Founder relocated and became postdoc | |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| , | Renamed Envue, Feb 2026 | |
| preclinics | Eystrup, Germany | Contract Research |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| DesignMedix | , | Shut down Aug 2020 |
| PL Developments | , | Parts of website taken over |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Recon Therapeutics | , | Shut down Jun 2017 |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Partner Therapeutics | Lexington, MA | Biologics |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| GEROPHARM | Moscow , Russia | Large drug maker |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Aplagen | , | No activity since 2008 |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Excelimmune | , | Closed Jul 2016 |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Piramal | Rabale, India | CDMO |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| , | Website down Jun 2025 - Dec 2025 | |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| UniteLabs | , | Shut Down |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| 121 Bio | , | Gone mid 2016 |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Corin | Cirencester , UK | Orthopedics |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Talee Bio | , | Renamed Spirovant Sciences |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| , | Acquired by Stryker, Sep 2024 | |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Siga | New York, NY | Small Molecules |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Trident Lifeline | Surat, India | Generics |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| Azanta | , | Acquired by Norgine, Mar 2020 |
 |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| InVasc Therapeutics | , | Shut down 2012 |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| MakroCare | Princeton, NJ | Drug Development Partner |
| , | Website down Jan 2026 - May 2026 | |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| , | Acquired by Immedica, Feb 2025 | |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| Alverix | , | Acquired by BD, Jan 2014 |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Aviv Biomedical | , | Shut down 2018 |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Stago | Gennevilliers, France | Diagnostics |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Medice | Iserlohn, Germany | Small Molecules |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| Intellirod Spine | , | Sold Assets late 2020 |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| ProtAffin | , | Winding Down |
| Alacrity Biosciences | , | Gone post-2011 |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Noble | Orlando, FL | Auto-injector Trainers |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| REV Clinical | Bakersfield, CA | Clinical Trials |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| , | Website down Dec 2025 - Apr 2026 | |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Sunol Molecular | , | Assets sold 2005 |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| BRAND | Wertheim, Germany | Liquid Handling |
| SphynKx Therapeutics | , | Gone |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| Surface Logix | , | Bought by Nano Terra |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Apini Therapeutics | , | |
| Abbott | Princeton, NJ | Diagnostics |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| Qrativ | , | Folded into nFerence |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| , | Website down Aug 2025 - Jan 2026 | |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| Retroject | , | Seems gone |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Viva Biotech | Shanghai , China | Contract Research |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| , | Website down Dec 2025 - Apr 2026 | |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| DiagnoCure | , | Liquidated, Apr 2016 |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Northern Lipids | , | Renamed Transferra |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Stimwave | , | Bankrupt, Oct 2022 |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Xact Medical | , | Website down Mar 2024 |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| , | Part of Normec | |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Weatherden | London, UK | Clinical Consulting |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| Octapharma | Lingolsheim, France | Plasma Products |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| Zumutor Biologics | Bangalore, India | Biologics |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Verus Pharmaceuticals | , | Dissolved |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| OptiVia Medical | , | Website looks pretty terrible |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| , | Pivoted to defense contracting, Jan 2026 | |
| Pathfinder Cell Therapy | , | Gone 2016 |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Acumed | Madrid, Spain | Medical Implants |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Biotox Sciences | , | Renamed BTS Research |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| Vedere Bio II | , | Shut down Mar 2023 |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Resilience | Mississauga, ON | Biomanufacturing |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Piramal | Ahmedabad, India | CDMO |
| Gerinda Therapeutics | , | Gone 2009 |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Atanse | , | Website gone, May 2018 |
| R/D Clinical Research | , | Website Gone |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| Able Labs | , | big FDA trouble, gone |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| VLST Corp | , | Wound Down, Jun 2013 |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Vericel | Cambridge, MA | Cellular Therapy |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Clarapath | Hawthorne, NY | Pathology Device |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
 |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Niche Generics | Arlesey, UK | Contract Generics |
| , | Acquired by Novanta, Jun 2026 | |
| , | Acquired by Tarsus Pharmaceuticals, Jul 2026, $75M + $490M milestones | |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Vivex Biologics | Atlanta, GA | Tissues |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| NuLife Sciences | , | Shell acquired for a security business |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| 7TM Pharma | , | Gone |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| GeneVivo | , | Unknown Fate |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| BioWa | , | Part of Kyowa Kirin Group |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| , | Website down Jul 2025 - Jan 2026 | |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| , | Website down May 2025 - Dec 2025 | |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Allievex | , | Shut down Feb 2025 |
| Sampled | Motherwell, UK | Biostorage |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Grove Instruments | , | Shut Down June 2017 |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Astrum | Paris, France | Clinical Development CRO |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| Northfield Laboratories | , | Bankrupt 2009 |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Otsuka | Tokushima, Japan | Small Molecules |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Altan Pharma | , | Acquired by Ethypharm |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Kar Bioanalytical | , | Seem gone |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Chiromics | , | Website now a penny stock shill |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Beta-Pro | , | Now Triangle Research Labs |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Lyman Biopharma Consulting | , | Switched to writing |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| , | Website down Jun 2025 - Dec 2025 | |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| , | Website down Jan 2026 - May 2026 | |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| SYNkinase | , | Shut down |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
 |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| , | Website down Feb 2026 - Jul 2026 | |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| BostonGene | Waltham, MA | Biomedical Software |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| , | Acquired by Instem, Jul 2025 | |
| Nura Bio | South SF, CA | Small Molecule |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Traversa Therapeutics | , | Bankrupt |
| TumorGen | San Diego, CA | Cancer Treatments |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Boston Biokeys | , | Gone June 2017 |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Samsara Sciences | , | Shut Down Mar 2020 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Molecular Sensing | , | Business revoked Aug 2019 |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| Targanta | , | Bought by The Medicines Company |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| Talima Therapeutics | , | Closed 2011 |
| Stago | Taverny, France | Diagnostics |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| Artivila Biopharma | Shenzhen, China | Artificial Intelligence-Driven Drug Discovery |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| Origen Therapeutics | , | Gone |
| , | Website down Jan 2026 - May 2026 | |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Wacker | Munich, Germany | Polymers, Resins |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| MicrofluidX | , | Renamed MFX |
| , | Acquired by Waters, 2023 | |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Knopp Biosciences | , | |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Xenova | , | Acquired by Celtic Pharma |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Creative Bioinformatics Consultants | , | Gone |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| , | Renamed SylamoreBio | |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| , | Renamed Hermes Biosciences | |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Phytomedics | , | Can't find info on it |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| Zylacta | , | No news 2015 - Oct 2024 |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| , | Website down Jan 2026 - May 2026 | |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Arete Therapeutics | , | Out of Business |
| MetaStat | , | Website gone May 2019; Shell Company |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| , | Website down Feb 2026 - Jul 2026; filings Late Jun 2024 - Dec 2025 | |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| DxTerity | Torrance, CA | Genomic Testing |
| Amigenics | , | Gone |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| , | Renamed PKx Bio, 2026 | |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| , | Seems gone, Feb 2026 | |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| DiObex | , | Shut Down 2009 |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Life Stem Genetics | , | Basically gone |
| Apalexo Biotechnologie | , | No info, probably gone |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Genocea Biosciences | , | Winding Down May 2022 |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Aitia | Cambridge, MA | Analytics |
| Serotiny | , | Acquired by J&J, 2023 |
| ChronTech Pharma | , | Became real estate company |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| , | Renamed EarliPoint Health, Oct 2025 | |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| SourceMDx | , | Assets Sold |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| Champions Biotechnology | , | Now Champions Oncology |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| CardioCreate | , | Shut Down Jun 2020 |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| VGX Pharmaceuticals | , | Merged with Inovio |
| Predictive Therapeutics | , | Renamed NeoTX |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Tal Medical | , | Gone |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| ViroMed | , | Renamed Helixmith |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Modular Medical | San Diego, CA | Insulin Pump |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| FusionBio | , | Website down Sep 2025 |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| Pathens | , | Website hijacked Sep 2020 |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| NeoCura | Beijing, China | Personalized Vaccines |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| Neotech | , | Website down Jan 2019 |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Cytovale | South SF, CA | Sepsis Detection |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| Pharmatrope | , | Absurd website 2020-2023 |
| VB Spine | Leesburg, VA | Spinal Implants |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| TheoremDx | , | Bankrupt Feb 2020 |
| Nasseo | , | Gone |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Leukosight | , | Gone, website is online pharmacy now |
| Novocell | , | Renamed Viacyte |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Basecamp Research | London, UK | AI-Biology Data |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| , | Website down Jul 2025 - Jan 2026 | |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| Minakem | Dunkerque , France | API Manufacturing |
| YMC Process Technologies | Devens, MA | Purification Technology |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Lipid Genomics | , | Seems unserious |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| PlaSalus | , | Amateurish looking |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Mirador Biomedical | , | Shut Down 2019 |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Novo Nordisk | Beijing, China | Inflammation Research |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Veramed | London, UK | Biostatistics and programming services |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Geneffects | , | Shut down Feb 2020 |
| Anesiva | , | Bankrupt 2010 |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| 89bio | San Francisco, CA | Liver Treatments |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Lotte Biologics | East Syracuse, NY | Biologics CDMO |
| Eden Biodesign | , | Bought by Watson |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Kalypsys | , | Gone |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Nusano | Valencia, CA | Radioisotopes |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| , | Website down Jun 2025 - Dec 2025 | |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Agenix | , | Gone, Website taken over |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| Halloran Consulting Group | Boston, MA | Consulting |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| LemnaGene | , | Acquired by Biolex 2005 |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| Calcionics | , | Shut down 2010 |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| , | Renamed Numerion Labs, Oct 2025 | |
| ChemPacific | Baltimore, MD | Chemicals |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Singulex | , | Shut down Jun 2019 |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| SineuGene | Beijing, China | Gene Therapy |
| Kegelbell | , | Shut down, Dec 2024 |
| Compugen | Holon, Israel | Biologics |
| Applied NeuroSolutions | , | Gone |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Alkem Labs | Mumbai, India | Generics |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| BGI | Shenzhen, China | Genetic Testing |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| Kallyope | New York, NY | Gut-brain axis focus |
| , | Renamed Cellixx, May 2026 | |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| NeuralInk | Fremont, CA | Neural Implants |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Curis | Lexington, MA | Small Molecules |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Proteotech | , | Website gone Jul 2015 |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Genta | , | Liquidation 2012 |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| Calzada | , | Renamed Polynovo |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Accord Healthcare | Ahmedabad , India | Generics |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| CATO SMS | , | Renamed Allucent, May 2022 |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| COOL-BIO | , | Gone |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Theracos | , | Renamed TheracosBio |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Vericel | Ann Arbor, MI | Cellular Products |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| |
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| , | Renamed KadisBio | |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| |
Redmond, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Anumana | Cambridge, MA | AI ECG reading |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Tasso | Seattle, WA | Blood-collection products |
| Avema Pharma | , | Bought by PL Developments |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Nanovelos | , | Subsumed into Nanogroup |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| , | Acquired by Xoma, Nov 2025 | |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Biotium | Fremont, CA | Fluorescent Reagents |
| GenoSpace | Boston, MA | Platform for genomic data |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Maxwell Biosciences | Austin, TX | Antivirals |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Vasade Biosciences | , | Gone |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| NeuroVia | , | Shut down 2019 |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| SenzaGen | Lund, Sweden | Genomic Assays |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| , | Acquired by Collate, Aug 2025 | |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| Terumo Medical | Elkton, MD | Medical Devices |
| Novonesis | Beijing, China | Enzymes |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| NanoVector | , | Gone 2019 |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
 |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| , | Renamed ExGen Dx, Jul 2025 | |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| VitamFero | , | Website gone Aug 2018 |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| 1CellBio | , | Gone Jun 2019 |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| Lannett | Trevose, PA | Generic Small Molecules |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Acquire by Savillex, Nov 2024 | |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Torpedo Bio | , | |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Orros Therapeutics | , | gone 2018 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| MicroPort | Shanghai, China | Medical Devices |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Lavipharm | Peania, Greece | Small molecules |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Epigen | , | Renamed Egenix, 2002 |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Avineuro | , | Website taken over Feb 2024 |
| Aliquot Solutions | , | Shut down Oct 2024 |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| , | Liquidating Feb 2025 | |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Recensa Therapeutics | , | Only employee gone 2018 |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| InteKrin | , | Owned by Coherus Biosciences |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Cellworks | South SF, CA | Biosimulations |
| , | Acquired by EPI, Mar 2022 | |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Sierra Neuropharmaceuticals | , | Not active |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| GlycoRegImmune | , | Changed name to GRI |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| CeNeRx | , | Shut Down, 2013 |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Piramal | Pithampur, India | CDMO |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| Novasecta | London, UK | Pharma Consultancy |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| VALOS | Genova, Italy | Clinical Statistics |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| Algenics | , | Website gone Dec 2015 |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Haini Pharmaceutical | Shanghai, China | Generics |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Infinitopes | Oxford, UK | Vaccines |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| Curamir Therapeutics | , | Shut down 2020 |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| BEAT BioTherapeutics | , | Closed 2017 |
| , | Acquired by Medicover, Apr 2026 | |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| , | Website down Aug 2025 - Jan 2026 | |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| Piramal | Hyderabad, India | CDMO |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Bayer | Barcelona, Spain | Small Molecules |
| IQVIA | Durham, NC | Clinical Research |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| GMP-Orphan France | , | Renamed Orphalan |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| LifeSensors | , | Website hijacked Feb 2025 |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| Apollomics | Foster City, CA | Cancer medicines |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Hookipa Biotech | , | Now Hookipa Pharma |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Cerebroscience | , | One employee, website gone |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Acidophil | , | Gone late 2022 |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| Nesher Technologies | , | Shut down Oct 2017 |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| , | Website down Jul 2025 - Dec 2025 | |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| , | Winding down Jan 2026 | |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Mithridion | , | Website Gone, Company appears to be as well |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Tolarex | , | Renamed Enlivex Therapeutics |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Heart Repair Technologies | , | |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Tisucor | , | Shut down Feb 2020 |
| , | Acquired by Merit Medical, Jun 2023 | |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| MicroPort | Clamart, France | Medical Devices |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| , | Shut down 2025 | |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| AstraZeneca | Boston, MA | Biologics |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| , | Website down Dec 2025 - Feb 2026 | |
| Kuroki Consulting | , | Shut down 2020 |
| Tactic Pharma | , | Website gone, Apr 2018 |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| , | Filings late Mar 2025 - Feb 2026 | |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| , | Acquired by Stryker, Oct 2024 | |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Nesch, LLC | , | Website gone Oct 2018 |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Batu Biologics | , | Gone 2019? |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Clearbridge Biomedics | , | Renamed Biolidics |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| AlloCure | , | Website Gone, Jul 2015 |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| AccuVein | Medford, NY | Vein Visualization |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| Ottobock | Duderstadt, Germany | Prosthetics |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| Accellacare | Knoxville, TN | Clinical Research |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| DDi | Monmouth Junction, NJ | Clinical Software |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| PPL Therapeutics | , | Sold in 2003 |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Amarin | Bridgewater, NJ | Small Molecules |
| Ampac Analytical | , | part of SK pharmteco |
| Orchestra BioMed | New Hope, PA | Medical devices |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Neose | , | Gone |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| ArisGen | , | Only employee has four other jobs |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Microphage | , | Bankrupt Jun 2013 |
| Cytiva | Marlborough, MA | Medical Devices |
| NIOX | Oxford, UK | Asthma management device |
| , | Website down Sep 2025 - Feb 2026 | |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Biotheneum | , | Gone |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| OD-OS | Irvine, CA | Retinal Laser |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| ObsEva | , | Shut down Feb 2024 |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| Picoseq | , | Renamed Depixus |
| Surgisense | , | Presumed gone |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Palmaz Scientific | , | Bankrupt, 2016 |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Endogenx | , | Website Gone Dec 2013 |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| , | Acquired by Scantox, Sep 2024 | |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| OcuDyne | , | AMD Medical Device |
| Peritia | Morrisville, NC | Consulting |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| MURO PHARM | , | Dissolved, May 2007 |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| IBA Analytics | , | Website gone Jul 2015 |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Quantificare | Suwanee, GA | Medical Imaging |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| Logan Medical Devices | , | Gone? |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| Moleac | Singapore, Singapore | Stroke Products |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Boston Scientific | Spencer, IN | Medical Devices |
| ASIT Biotech | , | Renamed DMS Imaging |
| Luye Pharma | Shanghai, China | Small Molecules |
| Zai Lab | Shanghai, China | Small Molecules |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Hana Biosciences | , | Now Talon Therapeutics |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| RK Pharma | Pearl River, NJ | Generics |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| |
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| Nanoferix | , | Renamed Pendant Biosciences |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Catylix | , | Shut down Oct 2021 |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Transdermal Technologies | , | Website Gone |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| Neurosave | , | Gone 2018 |
| Peptone | London, UK | Translational Biophysics |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| , | Renamed MindWalk, Sep 2025 | |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Catawba Research | Charlotte, NC | Clinical Research |
| bioRASI | Aventura, FL | Clinical Research |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| MabCo | , | Renamed Agenix |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| VAXX | , | Not sure what happened to them |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| , | Liquidating, May 2026 | |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Akubio | , | Bankrupt Sep 2007 |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| StaphOff Biotech | , | Shut down 2017 |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| Cilag | , | Joined J&J 1959 |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Neuronax | , | Renamed Axoltis Pharma |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| , | Website down Sep 2025 - Feb 2026 | |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Rx3 | , | Now Trius Therapeutics |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| Rosedale Medical | , | Now Intuity Medical |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| Biomatters | , | Renamed Geneious |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Genestack | Cambridge, UK | Genomics operating system |
| Abbott | Clonmel, Ireland | Stents |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| BioDatomics | , | Website gone Jan 2019 |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Serentrix | , | Seems gone Apr 2022 |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| ECI Biotech | , | Gone 2016 |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Biomedica | , | Now part of Oxford Biomedica |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| AVEO Oncology | Boston, MA | Small Molecules |
| , | Acquired by Eli Lilly, Jul 2026, $3.25B + $3.75M milestones | |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| , | Website down Aug 2025 - Jan 2026 | |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| 2 Bridge | Zoersel, Belgium | Consulting |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| Veeva Systems | Shanghai, China | Life Science Software |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Y's Therapeutics | , | Website Gone |
| Avenge Bio | , | Shut Down Jul 2024 |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Serica Technologies | , | Bought by Allergan |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Genialis | Boston, MA | Bioinformatics |
| ViraCyte | , | Renamed AlloVir |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| , | Acquired by Olon, 2024 | |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Summit Therapeutics | Miami, FL | Utrophin modulation technology |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| ALX Oncology | South SF, CA | Immuno-oncology |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| Quintessence Biotech | , | Biomimetic Separation |
| , | Shut down Jan 2025 | |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| , | Acquired by Sartorius, Apr 2025 | |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| , | Website down Jan 2026 - May 2026 | |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Sonexa Therapeutics | , | Closed 2013 |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| MiRus | Marietta, GA | Spine Implants |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| BioCydex | , | No info 2019 - Mar 2025 |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Biodel | , | Merged with Albireo, Oct 2016 |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| Humacyte | Durham, NC | Bioengineered Vessels |
| , | Website down Sep 2025 - Dec 2025 | |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| Geron | Foster City, CA | Small Molecule |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Ossur | Irvine, CA | Orthopedic Devices |
| Alchemgen | , | Gone |
| CoMind | London, UK | Non-invasive brain monitoring system |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| CYTOO Cell Architects | , | |
| StemCell2MAX | , | Website gone Apr 2019 |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Ambu | Ballerup, Denmark | Medical Devices |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Nvelop Therapeutics | , | |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| Antabio | Labège, France | Antibacterial drugs |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| QuantRx Biomedical | , | Shell company |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Itero Biopharmaceuticals | , | Website Gone |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Moon Surgical | Paris, France | Robotic Surgery System |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| IMMY | Norman, OK | Fungal Diagnostics |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Quest Clinical Research | , | Now part of eStudysite |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| AmCell Biosciences | , | Website gone Apr 2021 |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| Virco | , | Bought by J&J |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Indocruit | , | Gone |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Vrata Therapeutics | Cambridge, | |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Vivamer | , | Shut down, Jul 2015 |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| Pion | Billerica, MA | Dissolution Data |
| Angioslide | , | Gone, Oct 2009 |
| GenQual | , | Inactive, Jun 2017 |
| Tecnimede | Lisbon, Portugal | Generics |
| Createrna Science | Shanghai, China | Small Molecules |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| CG Therapeutics | , | Dissolved Jul 2013 |
| Solexa | , | Merged with Illumina 2006 |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Ribopro | Oss, Netherlands | mRNA Services |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Phase Forward | , | Bought by oracle |
| Autonomic Technologies | , | IP acquired by Unity HA |
| , | Website down Feb 2026 - Jul 2026 | |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Inscopix | Mountain View, CA | Miniature Microscope |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Plaxgen | , | Shut Down 2019 |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Pfizer | Kalamazoo, MI | Manufacturing |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Emergo by UL | Austin, TX | Medical device consulting |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| United Immunoassay | , | Business revoked Jan 2022 |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Furong Biotech | , | |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Okairos | , | Acquired by GSK, May 2013 |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| Repligen | Waltham, MA | Protein Manufacturing Equipment |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| Lucena | , | Failed |
| , | ||
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Amarin | Dublin, Ireland | Small Molecules |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| GeneoDx | , | Website gone Oct 2019 |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| Western Biologics | , | Dissolved, 1998 |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Nina Biotherapeutics | , | Gone, after 2015 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Avrygen | , | Website Gone, execs gone |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Carticept Medical | , | Dissolved Feb 2020 |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| GenturaDx | , | Bought by Luminex 2012 |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| Roche | Burgess Hill, UK | Diagnostics |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| Accellacare | Salisbury, NC | Clinical Research |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| , | Website down Oct 2025 - Feb 2026 | |
| Gene Labs | , | Bought by GSk 2008 |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Veeva Systems | Dublin, OH | Life Science Software |
| Celtaxsys | , | No longer active, Aug 2020 |
| PharmaVigilant | , | Gone 2014 |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| , | Renamed Mighty Therapeutics, Jun 2026 | |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Celerion | West Conshohocken, PA | Clinical Research |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Klogene Therapeutics | , | Gone 2019? |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| Nteryx | , | Changed name to Ardelyx |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Macrogen | , | Renamed Psomagen, 2019 |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| Ansh Labs | Webster, TX | Diagnostics Products |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| RxCelerate | Cambridge, UK | Contract Services |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| Actera Pharmaceuticals | , | Closed |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| , | Website down Sep 2025 - Feb 2026 | |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Verséa Health | Tampa, FL | Diagnostics |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Aureon Biosciences | , | Insolvency Proceedings |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| TeutoCell | , | Renamed Xell, 2014 |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Velia Therapeutics | , | Shut down Jan 2025 |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| Orexia | , | Acquired by Centessa |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| , | Acquired by CQ Medical, Oct 2023 | |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| Adlon Therapeutics | , | |
| 10BioSystems | , | Website Gone, Apr 2016 |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| GeneEx | , | Now RevDia |
| Cougar Biotechnology | , | Bought by J&J |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| , | Website taken over, Nov 2025 | |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Outlicensed sole product Sep 2021 | |
| Precursion Biosciences | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| PegaOne | , | Centessa Company |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| 1859, Inc. | , | Shut down Jul 2023 |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Tella | , | Website down May 2023 - Dec 2023 |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Genexa | , | Shut down before Nov 2023 |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Renamed Vaxanix, Jul 2026 | |
| MicroPort | Saluggia, Italy | Medical Devices |
| , | Acquired by Instem, Jul 2025 | |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| , | Acquired by eurifins, Sep 2024 | |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Getinge | Vendôme, France | Medical Technology |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| BioPhyZica | , | Gone 2016 |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Olymvax | Chengdu, China | Vaccines |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Z-Factor | , | Centessa Company |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| SNBL | , | Acquired by Altasciences |
| Advanced Genetic Technologies | , | No info |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Allometra | , | Gone |
| Solvanix | , | Shut down Nov 2023 |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Ennov | Paris, France | Software Solutions |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| Plexanome | , | Gone 2018 |
| Menarini | Florence, Italy | Biologics |
| Eurand | , | Now Aptalis |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| Defyrus | , | Website gone Nov 2017 |
| , | Acquired by BICO, Aug 2021, $15M | |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| Aspreva | , | Acquired by Vifor Pharma |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| SEQENS | Ecully, France | APIs, Ingredients |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| EndoStim | , | Shut down Jan 2020 |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| , | Website down Nov 2025 - Dec 2025 | |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Veravas | Oakdale, MN | Diagnostics |
| , | Website down Feb 2026 - Jun 2026 | |
| Genemo | , | Seems inactive, Jul 2024 |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Convergen LifeSciences | , | Renamed Genprex |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| ThauMDx | , | Closed down 2003, out of cash |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| , | Shut down Sep 2025 | |
| MilliporeSigma | Madison, WI | Small Molecules |
| Spirox | , | Bought by Stryker, Jul 2017 |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| D-Pharm | , | Website Gone, Aug 2016 |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Neurotronik | , | Most employees moved to InnerPulse |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Apollo Scientific | Manchester, UK | Research Products |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Almac | Durham, NC | Pharmaceutical Services |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Virapur | , | Acquired by Microbiologics, 2017 |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Diality | Irvine, CA | Hemodialysis System |
| , | Part of SBO Hearing, Feb 2026 | |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Suir Pharma | , | Bankrupt, May 2016 |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| NextCure | Beltsville, MD | Immune Therapies |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Mesoblast | New York , NY | Regenerative Medicine |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| Inspirata | North York, ON | Cancer Insights |
| Pathnostics | Irvine, CA | Diagnostics |
| Accellacare | Ames, IA | Clinical Research |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Amplifold | , | DNA origami nanotechnology |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Pharmaron | Louisville, KY | R&D Services |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| , | Website down Dec 2025 - Jun 2026 | |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| SereDigm | , | Gone Nov 2009 |
| BridGE Genomics | , | Gone 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Nuvelution Pharma | , | Gone 2020 |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| Rinat | , | Bought by Pfizer 2006 |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Analiza | Cleveland, OH | Physicochemical Services |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| , | Website down Feb 2026 - Jul 2026 | |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Tarpon Biosystems | , | Gone by 2017 |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| , | Shut down Dec 2025 | |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| , | Filings late Jun 2025 | |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing, CMO |
| Silenseed | , | Renamed Silexion |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Best Vascular | , | Now Best Vascular Novoste |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| CombImmune | , | Website Gone Jul 2015 |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| NB Therapeutics | , | Gone |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| NascaCell | , | German Aptamer company, not sure of fate |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| , | Acquired by MannKind, Oct 2025, $296M | |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| , | Shut down Oct 2025 | |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| GeneTrol | , | Merged with CytoPharm |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Novotech | Auckland , New Zealand | Clinical Research |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Integrated Genomics | , | Changed to Igenbio |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Vernacare | Bolton, UK | Surgical Devices |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| Outset Medical | San Jose, CA | Dialysis Device |
| Argonaut Manufacturing Services | Carlsbad, CA | CMO specializing in formulation, filling, finishing and final kitting. |
| ICN Pharmaceuticals | , | Now Valeant |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| , | Acquired by R-Biopharm, Jun 2022 | |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| PhytoMedical | , | Apparently Gone |
| Actylis | Port Washington, NY | Raw Materials |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| Progyny | New York, NY | IVF products |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| , | Website down Jul 2025 - Dec 2025 | |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| BioGaia | Stockholm, Sweden | Probiotics |
| Vernacare | Chorley, UK | Surgical Devices |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| Mendelian | London, UK | Rare Disease Diagnosis |
| Prescos | , | Shut down Feb 2014 |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| MSN Labs | Hyderabad, India | Generics |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Northstar Neuroscience | , | Dissolved |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| Aethox Therapeutics | London, UK | Inhibitors |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Talis Biomedical | , | |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Anavex Life Sciences | New York, NY | Small Molecules |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| , | Acquired by IQVIA | |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Salvat | Madrid, Spain | Small Molecules |
| , | Subsumed into Synoptics | |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Mobius Medical | Sydney, Australia | Clinical Research |
| STC Biologics | Newton, MA | Services |
| Ekteino | , | Closed, Dec 2016 |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Affymax | , | Dissolved 2014 |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| InvivoGen | San Diego, CA | Life Science Reagents |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| Gilead | Foster City, CA | Small Molecules |
| Nocimed | , | Renamed Aclarion |
| Genecare | , | Gone |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Lunit | Seoul, Korea | AI Image Analysis |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| EmerVax | , | Renamed Circurna |
| NeuroTherapeutics | , | Gone |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Orion Genomics | St. Louis, MO | Biomarkers |
| Biovays | , | Website Gone |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Anergix | , | Shut down Mar 2009 |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Vision Genomics | , | Website Gone, Jul 2016 |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Roslin Cells | , | Renamed RoslinCT |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| , | Shut Down Dec 2024 | |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| August Bioservices | Nashville, TN | Research & Development Services |
| , | Renamed Singulera, Nov 2025 | |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| , | Shut down Aug 2025 | |
| , | Abbott alums in Sioux Falls, ID, none on Linkedin Mar 2025 | |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Rheos Medicines | , | Shut down Dec 2022 |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| Serentis | , | Website Gone |
| IGF Oncology | , | Shut down 2022 |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| Cuda Pharmaceuticals | , | Presumed gone |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| Optime Therapeutics | , | Acquired by Lippomix |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Birdotech | Shanghai, China | CDRMO |
| Fairway Medical Technologies | , | Website gone |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| InnoCare | Nanjing, China | Cancer Treatments |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| , | Website taken over, Jan 2026 | |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| Nano Science | , | Acquired by EAG, 2006 |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Norgine | Hengoed, UK | Specialty Pharma |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Cearna Aesthetics | , | Product acquired by Allergan |
| , | Website down Jan 2026 - Mar 2026 | |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Evogene | Rehovot, Israel | Computational Biology |
| Mediso | Budapest, Hungary | Medical Imaging |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Neurogene | New York, NY | Genetic Therapies |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| KAI Research | , | Acquired by Navitas Life Sciences |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| LinKinVax | , | Rebranded as EnnoDC |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Ackley Hartnett | Langhorne, PA | Tablet Machines |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| , | Acquired by Sun Pharma, May 2025 | |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| BioFluentLabs | , | Shut down July 2012 |
| , | ||
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Primera Biosystems | , | Now PrimeraDx |
| OperaCRO | , | Now part of Tigermed |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Nycomed | , | Acquired by Takeda 2011 |
| Hasten Pharma | Hefei, China | Small Molecules |
| Vivacy | Archamps, France | Aesthetic Medicine |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| Inventa Biosciences | , | Not Active |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Lumanity | London, UK | Consulting |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| Meabco | , | |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| Plureon | , | Website gone, one employee after 17 years |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Orthofix International | Lewisville, TX | Medical Devices |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| |
Lyon, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| Stryker | Portage, MI | Medical Devices |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| Triage Wireless | , | Now named Sotera Wireless |
| Delpharm | Huningue, France | Contract Manufacturing |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Clina Research | , | Website gone Jul 2023 |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| , | Website down Dec 2025 - Apr 2026 | |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Gilead | Edmonton, AB | Small Molecules |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Certego Therapeutics | , | Seems gone May 2023 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| , | Acquired by Healx, Sep 2025 | |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| STB Lifesaving Technologies | , | Website gone |
| , | Website down Apr 2026 - Jun 2026 | |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Infinity Bio | Baltimore, MD | Reactome Services |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| PRACS Institute | , | Bankrupt 2013 |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Sprna | , | Website gone Jan 2020, no info |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Denizen Biologics | , | Shut down Mar 2023 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| Cytopeia | , | Acquired by BD, May 2008 |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| NTC | Milan, Italy | Generics |
| Microfluidics | Westwood, MA | High shear fluid processors |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Flow Eighteen38 | , | |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| TrialStat Solutions | Montreal, QC | eClinical |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| Vaxart | South SF, CA | Oral Vaccines |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| CanCure | , | No news 2017 - 2024 |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| Baccuico | , | Renamed Bactobio |
| Circadiance | Export, PA | CPAP Mask |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| 89bio | Rehovot, Israel | Liver Treatments |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Sygene Technologies | , | Website gone Nov 2018 |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| PredictImmune | , | Shut down Nov 2023 |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| Resilience | Blue Ash, OH | Biomanufacturing |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| CellCarta | Montréal, QC | Clinical Research |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Droice | New York, NY | AI Clinical Data |
| Zila | , | Bought by Tolmar, Jul 2009 |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Suvoda | Portland, OR | Clinical Trial Software |
| GTX Medical | , | Renamed ONWARD |
| , | Website down Sep 2025 - Dec 2025 | |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Eco Quest | , | Now Cynata Therapeutics |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Alper Biotechnology | , | Gone |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| Zambon | Bresso, Italy | Small Molecules |
| OFD Biopharma | Albany, OR | Lyophilization |
| Getinge | La Ciotat, France | Medical Technology |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Cellenion | Lyon, France | Single Cell Testing |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| Bastion Therapeutics | , | Shut down |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| Neuromatters | , | Shut down Dec 2019 |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| EuBiologics | Seoul, Korea | Vaccines |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| , | Acquired by IQVIA | |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| Analogic | Peabody, MA | Medical Imaging |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| , | Renamed Motive Health, Jul 2023 | |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| Sea Medical Systems | , | Gone |
| Inverness Medical | , | Renamed Alere 2011 |
| Flen Pharma | , | Now Flen Health |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Microbia-pe | , | Renamed Microbia |
| Vodori | Chicago, IL | Commercial Content Software |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Stago | Clarkston, GA | Diagnostics |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| Universal Precision Instruments, Inc. | , | |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| Journey Colab | , | Shut down Jan 2025 |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Alfacell | , | Now Tamir Biotechnology |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| NovoMedix | San Diego, CA | Small molecules |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| GenEndeavor | Hayward, CA | Diagnostics |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| Cytiva | Piscataway, NJ | Medical Devices |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Cell Therapy Ltd | , | Renamed Celixir |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| , | Website down Dec 2025 - Apr 2026 | |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Octapharma | Springe, Germany | Plasma Products |
| Tribiosys | , | Appears defunct, likely late 2007 |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Neuroptix | , | Renamed Cognoptix |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Esper Therapeutics | , | Shut down 2016 |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| , | Pandemic era government spongers | |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| , | Renamed Novakand Pharma, Sep 2025 | |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| , | Acquired by Genesis Biotechnology Group, Mar 2017 | |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| ImmuneMed | , | Shut Down |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Medicomp | , | Renamed ReactDx |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| , | Website down Oct 2025 - Feb 2026 | |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Supratek Pharma | , | Website gone Sep 2017 |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Indago | , | Renamed Lazurite |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Deinove | , | Bankrupt Mar 2023 |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| 3T Biosciences | South SF, CA | TCR Therapies |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| , | Renamed Mobia Medical, Feb 2026 | |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Meditrial | New York, NY | Clinical Services, Software |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| , | Website down Nov 2025 - Apr 2026 | |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Synthon | , | |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Telephus Medical | , | Now Telephus Biosciences |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
 |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| , | Website down Jul 2025 - Jan 2026 | |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| SOLADIS | , | Acquired by Efor, 2021 |
| Holloway America | Springfield, MO | Vessels, Tanks |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| , | No news 2021 - Jan 2026 | |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Ximedica | Plymouth, MN | Medical Device Services |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Tanai Therapeutics | , | Obesity Treatment |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| Bridge Laboratories | , | Gone 2013 |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| , | Gone Jan 2025 | |
| Hemanext | Lexington, MA | Transfusion Technologies |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| Covaris | Woburn, MA | DNA Sample Prep |
| Roowin | Riom, France | Chemical Synthesis |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| CellXplore | , | Gone |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| Adaptix | Oxford, UK | Medical imaging |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| , | Acquired by Maverix Medical, Dec 2023 | |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Applied Therapeutics | New York, NY | Small Molecules |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| RenovoRx | Mountain View, CA | Catheters |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Cyto360 | , | Website gone Aug 2018 |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Novotech | Bangkok, Thailand | Clinical Research |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| , | Website down Sep 2025 - Dec 2025 | |
| Stago | Asnières sur Seine, France | Diagnostics |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| CBM Biopharma | , | Shut down Nov 2020 |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| Novotech | Melbourne, Australia | Clinical Research |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| FHC | Bowdoin, ME | Medical Devices |
| ApoImmune | , | Gone 2014 |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Alte Biosciences | , | Gone, Apr 2016? |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Panther Orthopedics | , | Shut down Dec 2022 |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| RepRegen | , | Gone, 2014 |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Innovative BioTherapies | , | Gone |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| Ascend Genomics | , | Shut down |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| Erbe | Tübingen , Germany | Surgical Systems |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Cairn Research | Kent, UK | Scientific Instruments |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| Synostics | , | Gone 2014 |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| , | Renamed Transcend, Feb 2022 | |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| , | Website 404 Sep 2025 - Apr 2026 | |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| MSD | Dublin, Ireland | Women's Health Products |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Integer | Alden, NY | Medical & Surgical Devices |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| CisThera | , | Shut down Jan 2023 |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Ascenta Therapeutics | , | Gone |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Xhale | , | Acquired by Philips, Aug 2018 |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| ApcinteX | , | Centessa Company |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| NetBio | , | Renamed ANDE |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| NeuroFx | , | Renamed Theratome Bio |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| , | Acquired by Embecta, Mar 2026 | |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| AllerMAbs | , | Website gone Oct 2022 |
| , | Acquired by Medtronic, Jun 2026, $550M | |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Islet Sciences | , | Gone |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| Plexision | Pittsburgh, PA | Diagnostics |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| , | Renamed Yicura, Jun 2026 | |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Applied Integrin Sciences | , | Gone |
| Metabasis | , | Bought by Ligand |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Folia Biotech | , | Website Gone May 2018 |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| WideCELLS | , | Shut down Nov 2019 |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| NewHeart Devices | , | Gone |
| , | Website down Jul 2025 - Dec 2025 | |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Maroon Biotech | , | Gone Sep 2010 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| EnquBio | San Diego, CA | Contract Research & Services |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| TruGenomix | , | Renamed Polaris Genomics |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Adela | Toronto, ON | Liquid Biopsy |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Genex Pharma | Mumbai , India | Generics |
| , | Acquired by OraSure Technologies, Dec 2024, $25M | |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| , | Acquired by Lantheus, Jan 2025 | |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Curl Bio | , | Shut down Feb 2020 |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Soin Neuroscience | , | Seems like one guy |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| V-gene | , | Website gone, Aug 2017 |
| , | Acquired by HB Fuller, Jul 2023 | |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| ProtonDx | London, UK | Diagnostics |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| , | Website down Sep 2025 - Feb 2026 | |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| Artimplant | , | Bankrupt, 2013 |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| , | Acquired by Fujirebio, 2022 | |
| , | Website down May 2025 - Dec 2025 | |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| DNAe | London, UK | Next-gen Sequencing |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| Eversana | Chicago, IL | Commercialization Consulting |
| TRIFARMA | Rozzano, Italy | APIs |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Cue Biopharma | Boston, MA | Immunotherapy |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Restek | Bellefonte, PA | LCGC Equipment |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| , | Liquidation, Jun 2025 | |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| , | Website down Feb 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| Thyritope Biosciences | , | Closed Oct 2016 |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bioasis Technologies | , | Closing down Jun 2023 |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| 206 Ortho | , | Shut down 2021 |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| , | Website down Oct 2025 - Feb 2026 | |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| Simondr | , | Website gone, President has new job |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| NormOxys | , | Gone |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| IDRx | , | Acquired by GSK, Feb 2025 |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| Alcon | Houston, TX | Eye-Care Products |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| Sharp | Conshohocken, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Liquidating, Sep 2025 | |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| Qurasense | , | Renamed Qvin |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| MindRank | Shanghai, China | AI Drug Discovery |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Amadix | Valladolid, Spain | Diagnostic development |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Typharm | Norwich, UK | Generics |
| Celula | , | Acquired by NeoSeq |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Bioserv America | , | Shut down Aug 2024 |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Actium Biosystems | , | Gone 2013 |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| SynapDx | , | Shut down, Mar 2017 |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Genstruct | , | Now Selventa |
| , | Website down Oct 2025 - Feb 2026 | |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Infectex | , | Website taken over May 2020 |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| , | Website down Sep 2025 - Dec 2025 | |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Mepha | Basel, Switzerland | Generics |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| CD Genomics | Shirley, NY | Genomics Services |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| XO1 | , | Bought by J&J, Mar 2015 |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Lusis | Hayward, CA | Diagnostics |
| Vanquish Oncology | , | No news 2015-2021 |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| XtalPi | Shanghai, China | AI Drug Design |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| Medtronic | Mounds View, MN | Medical Devices |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| nplex biosciences | , | Renamed Nomic Bio |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Broken String Biosciences | England, UK | Gene Edited Cell & Gene Therapy |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Mitos Pharmaceuticals | , | Website Gone |
| Smithers | Akron, OH | Contract Research |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Fuji Yakuhin | Saitama, Japan | Generics |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Heraeus Medical | Dorado, PR | Medical Devices |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| Oncology Clinical Research | , | Gone |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| MantraPharma | Lévis, QC | Generics |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Protein Forest | , | Bought by Cell Biosciences |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| , | Renamed Torpedo Therapeutics | |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Ganymede | Palo Alto, CA | Lab Automation |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| amcure | , | Liquidated Sep 2024 |
| ReproSource | Marlborough, MA | Fertility Testing |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| CanTx | , | Website gone, Feb 2015 |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Affitech | , | Gone |
| Accelrys | , | Bought by Dassault, 2014 |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| , | Website down Dec 2025 - Apr 2026 | |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| , | Acquired by MMS, Feb 2025 | |
| BinaryBio | , | Out of business Jul 2015 |
| DDL | Irvine, CA | Device Testing |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Elanex Pharmaceuticals | , | Gone |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Halo Genomics | , | Bought by Agilent |
| Centocor | , | Renamed Janssen Biotech |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| Samil Pharmaceutical | Seoul, Korea | Eye Drops, Aseptic Filling, Formulation |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| PnuVax | , | No news 2017 - Aug 2024 |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Metris Therapeutics | , | Presumed Gone |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Medelis | Thompson's Station, TN | Clinical Research |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Stat One | Morrisvile, NC | eClinical |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| MIFCOR | , | Founders both gone Feb 2021 |
| , | Renamed Cytonome, Jul 2003 | |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Genmab | Plainsboro, NJ | Biologics |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| NEXGEL | Langhorne, PA | Hydrogels |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| , | Website down Aug 2025 - Jan 2026 | |
| , | Website down Jul 2025 - Oct 2025 | |
| , | Acquired by BMS, Dec 2025, $1.5B | |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Evestra | San Antonio, TX | Women's Health |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| Solano Pharmaceuticals | , | Website gone |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| DelSite | , | Bankrupt |
| Arstasis | , | Appears Gone Sep 2017 |
| Ortho Development | Draper, UT | Ortho Implants |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| HackScience | , | Renamed Cytera, Nov 2018 |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Ribonomics | , | Sold to MBL International |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| Getinge | Orléans, France | Medical Technology |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Cytoplex Biosciences | , | Gone |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Boston Scientific | Valencia, CA | Medical Devices |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| La Jolla Biologics | , | Website gone Nov 2014 |
| Alife | San Francisco, CA | AI-powered IVF |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| SanBio BV | Uden, Netherlands | Antibodies |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Tecomet | Arab, AL | Orthopedics CNC Machining |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| , | Website down Dec 2025 - Apr 2026 | |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| Apgene Bio | , | Shut down Oct 2020 |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| GeneDx | Stamford, CT | Genetic Data |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| Proteintech | Wuhan, China | Research Antibodies |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| InterGenetics | , | Assets auctioned |
| Hematogenix | Tinley Park, IL | Pharma Services |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| DDi | London, UK | Clinical Software |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Twistnostics | , | Renamed Scanogen |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Ipca Laboratories | Mumbai, India | APIs |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| CelerDx | , | Tiny startup that went nowhere |
| SegAna | , | Website down May 2021 - Sep 2021 |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Vessel Biosciences | , | Shut down Mar 2023 |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| 3D Biomatrix | , | Closed down |
| Quantificare | Maringa, Brazil | Medical Imaging |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| |
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| TissUse | Berlin, Germany | Multi Organ chip |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| RetiPharma | , | Dissolved Nov 2019 |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Cambridge Pharma | , | Rolled into parent, SMC |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| NextGen Sciences | , | Defaulted, sued by employees |
| Imalux | , | Ceased Operations, Apr 2014 |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| Getinge | Getinge, Sweden | Medical Technology |
| Helus Pharma | Toronto, ON | Psychedelics |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Antara Biosciences | , | Bankrupt 2007 |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| , | Website down Jan 2026 - May 2026 | |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| Vitrology | , | Acquired by SGS, May 2012 |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| RxGen | , | Renamed Virscio, Jan 2020 |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| TocopheRx | , | Gone before 2019 |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Avioq | Durham, NC | HIV Diagnostics |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Sciele Pharma | , | Bought by Shionogi |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| , | Website down Jan 2026 - May 2026 | |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Viva Biotech | Jiaxing , China | Contract Research |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Transmed Oncology | , | Gone? |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Bio Processing | , | Bought by Bio-rad |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| , | Website down Nov 2025 - Apr 2026 | |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Ansaris | , | Gone |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| Abgenix | , | Bought by Amgen 2006 |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Unigene Laboratories | , | Closed 2013 |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Covalent Bioscience | , | Shut down, 2025? |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| Excelya | Boulogne, France | Clinical Research |
| Sinobioway | , | |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| , | ||
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| , | Renamed Create Medicines, Oct 2025 | |
| Amplified Proteomics | , | Shut down Jan 2006 |
| 3DBio Therapeutics | , | Renamed PrintBio |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| , | Website down Jan 2026 - May 2026 | |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| SGS Quay Pharma | , | |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| , | Redirecting to Siemens, Feb 2026 | |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| NKMax America | , | Renamed NKGEN Biotech |
| Tuevol Therapeutics | , | Gone by 2020 |
| , | Acquired by Novartis, Oct 2025, $1.4B; Merged with Talaris Therapeutics, Oct 2023 | |
| NTRC | , | Now Oncolines |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| MyOme | Palo Alto, CA | Genomic Analysis |
| , | Website down Oct 2025 - Feb 2026 | |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| Relion | , | Shut down 2015? |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| Scynexis | Jersey City, NJ | Small Molecules |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| , | Website down Jul 2025 - Jan 2026 | |
| , | Website down Dec 2025 | |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| Pharmion | , | Acquired by Celgene 2007 |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| MabPrex | , | Out of business, 2016 |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| Pharos Dx | , | Gone |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Biohit | Helsinki, Finland | Diagnostics |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Yao Pharma | Chongqing, China | APIs, Generics |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Synairgen | Southampton, UK | Inhaled Biologics |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Getinge | Wayne, NJ | Medical Technology |
| , | Website down Jul 2025 - Dec 2025 | |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Belmont Medical | Billerica, MA | Body Temperature Management Devices |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| Norton Scientific | , | Website Gone, Oct 2014 |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| Minimally Invasive Devices | , | Shut down |
| ImmuneWorks | , | Website gone, Apr 2018 |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Evonik Industries | Birmingham, AL | Biomaterials |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Oxehealth | , | Pivoted to mental health platform |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Healogix | Doylestown, PA | Consulting |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| , | Acquired by Aptean, Oct 2016 | |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Activ Surgical | Boston, MA | Surgical Software |
| 149 Medical | , | Shut down Dec 2022 |
| Pharma Medica | Toronto, ON | Clinical Services |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| , | Website down Jul 2025 - Dec 2025 | |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Biocious Life Sciences | , | Now Agilent |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| Lacerta Therapeutics | , | Shut down May 2024 |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| Eleven P15 | , | Shut down |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| NinePoint Medical | , | Seems gone Sep 2020 |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| CanBas | Shizuoka, Japan | Small Molecules |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Autotelic | , | Gone 2022 |
| Quiescence Technologies | , | Website Gone |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Axya medical | , | Gone 2012 |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Evvy | New York, NY | At-home vaginal microbiome test |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| ROKIT | Seoul, Korea | Organ Regeneration |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| DNAMx | , | Renamed Adela |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| , | Website down Jan 2026 - May 2026 | |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Pharmaron | Ningbo, China | R&D Services |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| Serometrix | , | More of an aspiration than a company |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| Grid Biosciences | New Territories, China | Vaccines |
| Mattson Jack | , | Now Kantar Health 2009 |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| Alera Labs | Durham, NC | Contract Research & Services |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| Roche | Mississauga, ON | Small Molecules |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| Blansett Pharmacal | , | Gone Jan 2019 |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| , | Website down Dec 2025 - Apr 2026 | |
| Anulex Technologies | , | Closed 2014 |
| Stada | Bad Vilbel, Germany | Generics |
| , | Website gone Feb 2026 - Jun 2026 | |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Jet Life Sciences | Hyderabad, India | APIs |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Amoytop Biotech | Xiamen, China | Biologics |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| , | No news 2019 - Sep 2025 | |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| ProPharma Group | Washington, DC | Consulting |
| Carver Biosciences | , | |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| C3 Jian | , | Now C3J Therapeutics |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| Argolight | Pessac, France | Microscopes |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Medicure | Princeton, NJ | Small Molecule |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| AdvaStim | , | Shut down, Dec 2017 |
| Ankon Technologies | Wuhan, China | Medical Devices |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| WiseGene | , | Website gone jan 2020 |
| Keenova | Malvern, PA | Small Molecules |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| Hologic | Beijing, China | Diagnostic, Imaging |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Stryker | Flower Mound, TX | Medical Devices |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Tecomet | Chelsea, MI | CNC Machining, Polymer Machining, Orthopedics |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| , | Acquired by Lonza, Jun 2023 | |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| , | Renamed THX Pharma, Sep 2025 | |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Atugen | , | Acquired by SR Pharma 2005 |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Attenuon | , | Now Tactic |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| GT Biologics | , | Renamed 4D Pharma Research |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| , | Bankrupt, ceased operations Mar 2026 | |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| CoAxia | , | Closed down Spring 2013 |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| DMD Therapeutics | , | Gone Nov 2018 |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| Proteorex | , | Gone Nov 2017 |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Eyetech | , | Website Gone 6-16-12 |
| RhinoCyte | , | Website moved to a marketing agency domain |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| Trudell Medical | London, ON | Inhalation Devices |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Gamma Therapeutics | , | Gone |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Icarus Medical | Charlottesville, VA | Knee Braces |
| , | Acquired by Epitype, Oct 2025 | |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| Limerick Bio | , | Gone 2011 |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Louisville Bioscience | , | Now LBIdx |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| , | Website down Nov 2025 - Feb 2026 | |
| Salgomed | , | Shut down Apr 2022 |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| Mardil Medical | , | Website gone Feb 2021 |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| Pierce | , | Part of Thermo Fisher |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Epigenetix | , | No annual report filed 2013-2019 |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| , | Website taken over Feb 2026 | |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| SiliCycle | Québec, QC | Separation Technologies |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Idience | San Francisco, CA | Cancer Therapies |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| SoBran | Falls Church, VA | Preclinical Services |
| NeuTec Pharma | , | Shut down 2010 |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| AbRegen | , | Website gone, Mar 2019 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Cunde Medical | , | mRNA Cell Therapy combo |
| PX Biosolutions | , | Gone |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Anvyl | , | Website gone Jan 2021 |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Getinge | Mahwah, NJ | Medical Technology |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| PulmoGeniX | , | No business filings 2016-2020 |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| AzurRx | , | Merged into First Wave Bio |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Cell>Point | , | Cant find any confirmation they are active |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| , | Website down Oct 2025 - Feb 2026 | |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Azano Biotech | , | Now Sandia Biotech |
| Wheaton | , | Renamed DWK Life Sciences |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Platelet BioGenesis | , | renamed PlateletBio |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| , | No info 2019 - Mar 2026 | |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Inductive Bio | Virtual, US | Compound Optimization |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| Celest Therapeutics | , | |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| Cato Research | , | Renamed CATO-SMS |
| QL Biopharm | Beijing, China | Biologics |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Cebix | , | Shut down, Feb 2015 |
| Remedium Bio | Needham, MA | Gene Therapy |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| Metabolex | , | Now CymaBay Therapeutics |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| Rytvel Biotechnology | , | |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Sharp | Macungie, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| Nanosonics | Manchester, UK | Ultrasound |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| , | New Apr 2023, website not ready Aug 2023 - Jun 2026 | |
| Genae Associates | , | Acquired by IQVIA |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| 14M Genomics | , | Shut down, Feb 2016 |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| Ipsen | Sumter, SC | Biologics |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Sinotherapeutics | Shanghai, China | Generics |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| |
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Padagis | Allegan, MI | Generics |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| nference | Cambridge, MA | Clinical AI |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| BHR Pharma | , | Subsidiary of Besins |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| , | Winding down Apr 2026 | |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| PharmacoFore | , | Now Signature Therapeutics |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| ImmuNext | , | Website gone Feb 2025 |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| GemacBio | , | Renamed PolyNeuroS |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Perceptive | Nottingham, UK | Medical Imaging |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| JAMP Pharma | Boucherville, QC | Generics |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| , | Acquired by AbbVie, Aug 2025 | |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| Pharmexon | Prague, Czech Republic | Consulting |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| CSL Behring | King of Prussia, PA | Biologics |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| Quell Therapeutics | London, UK | Treg cell therapies |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Advanced Peptides | , | No business filings since 2011 |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| ViaCord | , | Part of PerkinElmer |
| Kivu Bioscience | San Francisco, CA | ADCs |
| Vista.ai | Palo Alto, CA | MRI Software |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Incyte | Wilmington, DE | Small Molecules |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| , | Website down Jul 2025 - Dec 2025 | |
| Innogenix | Amityville, NY | Generics |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Merck KGaA | Singapore, Singapore | |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| , | Acquired by Ligthouse Lab Services | |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Novonesis | North Rocks, Australia | Enzymes |
| Agendia | Irvine, CA | Breast Cancer Assay |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Cell Genesys | , | Merged with BioSante |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| THORASYS | Montréal, QC | Lung Function Measurement |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Akkadix | , | Gone 2001 |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Altos Therapeutics | , | Gone Jun 2019 |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| Patronus Biotech | Singapore, | |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| NeoTrail Therapeutics | , | |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| , | being Acquired by Chugai, Oct 2025 | |
| Tecomet | Baden-Dattwil, Switzerland | Bone In-Growth Coating, Bearing Surface Solutions, Polymer Machining, Sterilized Packaging |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Corza Medical | Shanghai, China | Surgical Devices |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| Trigemina | , | Shut down Aug 2020 |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| InterX | , | Acquired by NeoTX, May 2022 |
| Huons | Seongnam, Korea | Small Molecules |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Anergis | , | Liquidating, Jan 2021 |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Procertus | , | Website Gone, Apr 2016 |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| , | Website down Sep 2025 - Feb 2026 | |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| FIT Biotech | , | Bankrupt Feb 2019 |
| Ectycell | , | Part of Cellectis |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| YishengBio | , | Now YS Biopharma |
| , | No news 2021 - Jan 2026 | |
| Ambion | , | Bought by Applied Biosystems 2006 |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Tecomet | Manchester, NH | Case Design, CNC Machining, Injection Molding, Metal Forming, Vacuum Forming |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Madison Vaccines | , | Website gone Dec 2019 |
| , | Rebranded as VivoSim, Apr 2025 | |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| ImmBio | , | Shut down Nov 2019 |
| ABS Bio | New Castle, DE | Custom Bioreagents |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Epixis | , | Acquired by VBI Vaccines |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Caidya | Raleigh, NC | Clinical Research Organization |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Pentapharm | Basel, Switzerland | APIs |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Hemanext | Avon, MA | Transfusion Technologies |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| , | Renamed Revr Jan 2026 | |
| Celavie Biosciences | , | Shut down Mar 2024 |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| , | Seems to be News website, Jan 2026 | |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Genometry | , | Shut down Dec 2019 |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| Dipharma | Baranzate, Italy | APIs, Generics |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Premier Biomedical | , | Pivoted out of life science |
| , | Acquired by Crypto Group, Jan 2025 | |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| Deimos Biosciences | , | |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| , | Part of Greenpharma | |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Glysantis | , | Shut down Late 2020 |
| , | Shut down May 2025 | |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Inventprise | Redmond, WA | Vaccines |
| , | Shut down Jul 2026; aka Integrity Implants | |
| MolPlex | , | Insolvent, 2016 |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Biokit | , | Rolled into Werfen |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Tarsa Therapeutics | , | Product rights acquired |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| Novitium Pharma | East Windsor, NJ | Generics |
| Parexel | Harrow, UK | Clinical Research |
| , | Website down May 2025 - Sep 2025 | |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Quantificare | Biot, France | Medical Imaging |
| AndroScience | , | Ancient website, no news 2014-2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Station X | , | Website Gone Mar 2018 |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| Gossamer Bio | San Diego, CA | Small Molecules |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| , | No news 2020 - Jun 2026 | |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Redpoint Bio | , | Inactive |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| , | No news 2021 - Jun 2026 | |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| , | Acquired by Source BioScience, Apr 2025 | |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| Barc Lab | , | Renamed Cerba Research |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Rhaeos | Evanston, IL | Shunt Monitor |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Altheos | , | Closed |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Cyberval | , | Seems inactive Feb 2024 |
| Celerion | Montreal, QC | Clinical Research |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| , | Website down Dec 2025 - Feb 2026 | |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| Protelica | , | Dissolved, Dec 2006 |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Medtronic | Memphis, TN | Medical Devices |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| CorTechs Labs | , | Renamed Cortechs.ai |
| AssureRx | , | Renamed Assurex Health |
| Kirgen | Shanghai, China | Lab Supplies |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Piramal | Digwal, India | CDMO |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| NovoLipid | , | Website Gone |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| BBOT | South SF, CA | RAS-targeted small molecules |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| RSSL | Reading, UK | Analytical Services |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| Getinge | Rastatt, Germany | Medical Technology |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| , | Winding down Jan 2026 | |
| Dropshot Therapeutics | , | |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Novelty Nobility | Seongnam, Korea | ADCs |
| SARcode | , | Bought by Shire Mar 2013 |
| Apic Bio | , | Shut down Jan 2024 |
| Spirometrix | , | Renamed Spirosure |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| , | Gone Jan 2026 | |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| ConjuChem | , | Bankrupt 2011 |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| Humanyx | , | No website, Seems gone |
| , | Website down Oct 2025 - Feb 2026 | |
| Azad Pharma | Montreal, QC | APIs, generics |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| , | Merged into Meridian Bioscience | |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| CGT Global | Folsom, CA | Tissue Sourcing |
| restor3d | Durham, NC | 3D printed implants and devices |
| Nuevolution | , | Bought by Amgen May 2019 |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| ERBC | Baugy, France | Non clinical CRO |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Sermes | Madrid, Spain | Full Service CRO |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Immunovaccine | , | Rebranded IMV, 2018 |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| Cadex Genomics | , | Shut down Jul 2024 |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Inform Genomics | , | Website Gone Nov 2018 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| , | Shut down Nov 2025 | |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| XenaCare | , | Gone |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Dermagen | , | Website Gone, scammy sites with similar name |
| , | Shut down Fall 2025 | |
| CyteGen | , | 2015 founded, website never active |
| , | Acquired by Versiti, Jul 2023 | |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| BIOMODEX | , | Acquired by Mentice |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| ZyStor | , | Bought by BioMarin, closed |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| BioMarin Pharmaceutical | London, UK | Biologics |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| Bionsight | Seoul, Korea | Database For Research |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Calibrant | , | Closed |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Pace | San German, PR | Analytical Testing, CDMO |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Tico Bio | , | Renamed Inso Biosciences |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Selventa | , | Closed 2016 |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Pathwork Diagnostics | , | Closed 2013 |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Biocode Hycel | , | Website gone |
| GenoMatix | , | Acquired by Intrexon |
| Sanofi | Frankfurt, Germany | Small Molecules |
| InCytu | , | Website gone Jul 2015 |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| tte laboratories | , | Acquired by Transcat |
| Lab901 | , | Bought by Agilent |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| Curium | , | Dissolved, Mar 2015 |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| , | Acquired by Castle Biosciences, May 2025 | |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| CMD Medtech | Columbus, OH | Medical Device Development |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Gallus | , | Bought by Patheon, Aug 2014 |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Cellex | , | Presumed Gone |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| Therics | , | Acquired by Integra |
| CMD Bioscience | , | Closed, 2015 |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| Adrenergics | , | Gone Sep 2017 |
| , | Website down Jun 2025 - Dec 2025 | |
| NeuExcell Therapeutics | King of Prussia, PA | Gene Therapy for Neural Regeneration & Repair |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Vali Nanomedical | , | Gone 2016 |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| Avecris | Singapore, Singapore | Gene Delivery |
| Vernacare | Maple, ON | Surgical Devices |
| Stemnovate | Cambridge, UK | Research Cells |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| MyBiotech | Überherrn, Germany | Bioreactors |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| , | Website down Feb 2026 - Jul 2026 | |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| GenSure | Shijiazhuang, China | Diagnostics |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Mednoxa | , | Website gone Jan 2020 |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Ottobock | Vienna, Austria | Prosthetics |
| TissueNetix | , | Gone Feb 2018 |
| Empatica | Cambridge, MA | Seizure Detection |
| ErVimmune | Lyon, France | Cancer Vaccines |
| , | Renamed Proxoma, Jan 2026 | |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| BA Sciences | Morrisville, NC | Analytical Services |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| GeNO | , | Renamed Vero Biotech, 2018 |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Octant Biotech | Emeryville, CA | Small Molecules |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Synlogic | , | Shut down Sep 2024 |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| Makefield Therapeutics | , | Website Gone |
| Neuron23 | South SF, CA | AI-drug discovery |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Abgent | , | Renamed Abcepta, 2019 |
| Qardio | Covina, CA | Portable Heart Monitors |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| Piramal | Ennore, India | CDMO |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Seer | Redwood City, CA | Early Detection |
| Apotex | Toronto, ON | Small Molecule Generics |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| Syneos Health | Newtown, PA | Clinical Development |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Nanobiotix | Paris, France | Nanoparticles |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| PepVax | , | Gone 2024 |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| VitalMedix | , | Out of Money 2010 |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| IQVIA | Durham, NC | Clinical Research |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Syneos Health | Morrisville, NC | Clinical Development |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| HpVac | , | Renamed Atopia Therapeutics |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Generex Biotechnology | , | Website gone Feb 2024 |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Onyvax | , | Assets Apparently Acquired |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| Elucida Oncology | , | Shut Down Jul 2024 |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| ProCrysta Biologix | , | Shut down 2018 |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| Correlogic | , | Assets bought by Vermillion 2011 |
| Piper Therapeutics | , | Website gone May 2020 |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| Actis Biologics | , | Gone |
| Diassess | , | Renamed Lucira Health |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Visitube | , | No website Mar 2020 |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| CereSpir | , | No news 2020 - Nov 2024 |
| Neugenesis | , | Bought by Intrexon, 2011 |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| CranioVation | , | Shut down Jan 2022 |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Henderson Morley | , | Bankrupt |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Anthra Pharmaceutical | , | Gone |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Apofore | , | Shut down, Dec 2015 |
| , | Website down Dec 2025 - Apr 2026 | |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| Cancer Insight | , | Renamed LumaBridge |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Michrom | , | Bought by Bruker, Feb 2011 |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| Greenstone Biosciences | Palo Alto, CA | |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Hutchmed | Hong Kong, China | Oral drugs |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| Bracco | Milan, Italy | Imaging |
| Getinge | Tournefeuille, France | Medical Technology |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Allogene Therapeutics | South SF, CA | CAR-T |
| Amp Orthopedics | , | Shut down, 2012 |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| Emulate | Boston, MA | Organs-on-chips |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| Abcam | Cambridge, UK | Antibodies |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Biopar | , | Gone? |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| Clario | Philadelphia, PA | Clinical Services |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Baxter | Alliston, ON | Medication Delivery |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| Delpharm | Lille, France | Contract Manufacturing |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| Centricity Research | Toronto, ON | Clinical Research |
| Dey LP | , | Bought by Mylan 2007 |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Arraystar | Rockville, MD | Microarrays |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| , | Website down Jan 2026 - May 2026 | |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| UniXell Biotechnology | Shanghai, China | Cell Therapy |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Nido Surgical | , | Shut down Apr 2022 |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| , | Website down Feb 2026 - Jul 2026 | |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| ExcelseBio | , | Part of IntegrityBio |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Élancé Therapeutics | , | Bispecific Antibodies |
| IDM Pharma | , | Acquired by Takeda |
| Aspira Scientific | , | Gone Nov 2015 |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| Celerion | Tempe, AZ | Clinical Research |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| , | Acquired by Axora Medical, Jan 2026 | |
| Sequoia Pharmaceuticals | , | Folded |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| , | Website down May 2025 - Sep 2025 | |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| OccuRx | , | Merged into Certa Therapeutics |
| Arna Pharma | Sydney, Australia | Generics |
| Mendaera | San Mateo, CA | Medical Robotics |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Imcyse | , | Liquidating, Jun 2025 |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Novacta | , | Website Gone, no info |
| , | Website taken over Jun 2026 | |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Stiefel | , | Acquired by GSK |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| LinkChem | Shanghai, China | CDMO |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| ClinOne | Needham, MA | Clinical Patient Platform |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| , | ||
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Slainte Bioceuticals | , | Gone |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Bayer | Berlin, Germany | Small Molecules |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Reserva | , | Renamed NeurMedix, 2016 |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| Microsure | Son, Netherlands | Surgical Robots |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| , | Website taken over Jul 2026 | |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| Pfizer | Surrey, UK | Consumer Healthcare |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| Amniox Medical | , | Folded into BioTissue |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| , | Website down May 2025 - Dec 2025 | |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Revvity | Waltham, MA | Diagnostics, Services |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Guardion Health Sciences | , | Shut down |
| Cell Targeting Inc | , | Bought by Biotime |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| , | Renamed Ensera, Oct 2025 | |
| Interferon Source | , | Bought by PBL Assay Science |
| , | Website messed up, single employee, Dec 2025 | |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| AlphaGenix | , | Gone 2014 |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Pangaea Pharmaceuticals | , | Became Zycos |
| COR Clinical Research | , | Shut down after owner passed |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| , | Website down Nov 2025 - Apr 2026 | |
| Rho | Durham, NC | Clinical Research |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Intica Biomedical | , | Bankrupt 2014 |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| SWITCH Biotech | , | Gone, 2020 |
| AMRI | , | Renamed Curia, Jul 2021 |
| , | Website down Feb 2026 - Jul 2026 | |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| EQL Pharma | Lund, Sweden | Generics |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| BioCrea | , | Website Gone, Feb 2018 |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| NuVascular Technologies | , | Shut down Nov 2021 |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| BrainCells | , | Website gone Feb 2014 |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| , | Website down Sep 2025 - Dec 2025 | |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Keenova | Bridgewater, NJ | Small Molecules |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| Nabla Bio | Cambridge, MA | Antibody Design |
| Medica | , | Gone before 2019 |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| BojiMed | Guangzhou, China | Clinical Research |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| , | Website down Jan 2026 - May 2026 | |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| Nuvik Therapeutics | , | No website, very little info |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Provecs Medical | , | Gone Nov 2019 |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Qynapse | Boston, MA | Imaging Analysis |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Gentell | Yardley, PA | Wound Care |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Vyriad | Rochester, MN | Immunovirotherapy |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Tolerx | , | Shut Down 2011 |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Lung Bioengineering | , | Part of United Therapeutics |
| Menarini | Dresden, Germany | Small Molecules |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Urogenix | , | Acquired by Astellas |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Myrexis | , | Liquidating 2013 |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Symbollon | , | Gone |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| Clinical Scientist Group | , | Website gone, employee gone |
| Precision Virologics | , | Precision Virologics |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Signant Health | Horsham, PA | eClinical Solutions |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| Organogenesis | Canton, MA | Biologics |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Revotek | , | Website down May 2023 - Sep 2023 |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Libra Clinical Research Associates | , | Gone |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| KeraCure | , | Gone 2014 |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Iomai | , | Bought by Intercell 2008 |
| Medallion Therapeutics | , | Shut down 2018 |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| AbBaltis | Kent, UK | Plasmas & Sera |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Sharp | Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| hC Bioscience | , | Shut down Mar 2025 |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| ID Pharma | , | Acquired by I'rom Group |
| Human Genome Sciences | , | Bought by GSK |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| Hesperos | Orlando, FL | Human-on-a-chip |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| , | Acquired by Teva, Jun 2026, $700M | |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| , | Acquired by Instem, Jul 2025 | |
| AdipoGenix | , | Gone Jun 2012 |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Senetek | , | Not sure what happened, no site, seem gone |
| Shionogi | Florham Park, NJ | Small Molecules |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| TheraCoat | , | Renamed UroGen Pharma |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| Yunovia | Hwaseong, Korea | Small Molecules |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Asarina Pharma | , | Winding down Jul 2024 |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| TriVirix | , | Now Nortech Life Sciences |
| Palingen | , | Renamed IGM Biosciences |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Bioventus | Durham, NC | Orthobiologics |
| Omnitura | , | Website gone Jan 2022 |
| QuantuMDx | Newcastle, UK | Diagnostics |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| , | Website taken over, Feb 2026 | |
| Safecor Medical | , | Shut down Apr 2021 |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Graybug | , | Now Graybug Vision |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Verici Dx | Franklin, TN | Kidney Transplant Technology |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Prominex | San Diego, CA | POC Diagnostics |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Ergomed | Mumbai, India | Clinical Research |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| Imris | Chaska, MN | Image Guided Therapy Solutions |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Teva | Toronto, ON | Small Molecules |
| Epocal | , | Acquired by Alere, Feb 2013 |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Bionode | , | Shut down Mar 2024 |
| Balance Therapeutics | , | Gone late 2020 |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Medarex | , | Bought by BMS 2009 |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Alms Therapeutics | , | Gone Jul 2022 |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| algorithmRx | , | Now Venebio |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| , | Renamed Trace Biosciences | |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| PACT Pharma | , | Shut down Sep 2023 |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Abselion | Cambridge, UK | Biologics Quantification |
| , | Acquired by Uniphar | |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| X7 Research | , | Website hijacked Feb 2025 |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Biolab | São Paulo, Brazil | Small Molecules |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Xencor | Pasadena, CA | Antibody Discovery |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| Pharmathen | Marousi, Greece | Generics |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Novotech | Seoul, Korea | Clinical Research |
| TFS | Lund, Sweden | Clinical Research |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Nexus Spine | Draper, UT | Spinal Implants |
| Lupin | Mandideep, India | Generics |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Menarini | L'Aquila, Italy | Small Molecules |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| , | Website taken over Jun 2026 | |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Evosep | Odense, Denmark | Automated Sample Prep |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| DoveTree Medicines | , | |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Keenova | Dublin, Ireland | Small Molecules |
| , | Acquired by Affluent Medical, Feb 2026 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| Sanofi | Midrand, South Africa | Biologics |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Novacea | , | Bought by Transcept |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| , | Website down Oct 2025 - Feb 2026 | |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Virscio | New Haven, CT | Contract Research & Consulting |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| NK CellTech | Shanghai, China | Cell Therapies |
| Ventaleon | , | Shut down 2020 |
| , | Website down Jan 2026 - May 2026 | |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Biotia | Long Island City, NY | AI Genomics |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Obexia | , | Gone |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| MantaBio | Beverly, MA | Real-time PCR System |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| VasculoMedics | , | Gone 2019 |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| , | Renamed Faeth Therapeutics, Jun 2026 | |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Waters | Milford, MA | Chromatography & Chemistry |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Apolife | , | Renamed Biosavita |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Librede | , | Acquired by Lygos, Jan 2020 |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| Repco Development Technologies | , | Renamed 3Dispense |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Roche | Basel, Switzerland | Diagnostics |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Gameto | New York, NY | Female Fertility Extension |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| Sharp | Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Genitope | , | Wound Down |
| MMI Genomics | , | Assets bought by Neogen |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Tethys Bioscience | , | Shut Down, late 2013 |
| , | Website down Jun 2025 - Dec 2025 | |
| FemtoVox | , | |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| |
Neuried, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| , | No news 2020 - Jun 2026 | |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| Trilobio | San Francisco, CA | Lab Automation |
| AblaCor | , | Shut down May 2019 |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| , | Website down Jul 2025 - Oct 2025 | |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| , | Acquired by ETAP Group, Oct 2023 | |
| MWG Biotech | , | Owned by Eurofins |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| Abbott | Donegal, Ireland | Diagnostics |
| Nexgenia | , | Gone Dec 2019 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Macrocure | , | Merged into Leap Therapeutics |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| Green Cross | , | Renamed GC Pharma |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Santen | Tampere, Finland | Ophthalmics |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| , | Website down Jan 2026 - May 2026 | |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| Biocodex | Gentilly, France | Microbiota Treatments |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| Poxel | Lyon, France | Drugs for metabolic disease |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| GeoVax | Smyrna, GA | Vaccines |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Quanta Biosciences | , | Renamed QuantaBio |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Quanticate | Bangalore, India | Clinical Research |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| Ergomed | Kiev, Ukraine | Clinical Research |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| , | No news 2020 - Nov 2025 | |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| GenoImmune | , | |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Sebra | Tucson, AZ | Tube Sealer |
| Refined Diagnostics | Münster, Germany | Lasers |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Aegea Biotechnologies | , | |
| Regulaxis | , | No news 2020-2024 |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Bard1 | , | Renamed INOVIQ |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Medreich | Bengaluru, India | CDMO |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| Xori | , | Antibody Platform sold between 2011-2014 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Sojournix | , | Shut down Jun 2021 |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Summation Bio | , | Shut down May 2023 |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| ModeX Therapeutics | Weston, MA | Biologics |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| Biological Dynamics | , | Shut down Jul 2024 |
| , | Subsumed into Synoptics | |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Xencor | San Diego, CA | Antibody Discovery |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Avecia | , | Bought by Nitto Denko |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Gencove | New York, NY | Genome Sequencing |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| Berg Pharma | , | Now just Berg |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| , | Acquired by Avania, Oct 2024 | |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Pfizer | Clondalkin, Ireland | Biologics |
| , | Shut down Mar 2026 | |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Sanarus | , | Acquired by Hologic, 2020 |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| LipimetiX Development | , | Website gone, Jan 2020 |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| VastBiome | , | Renamed PragmaBiome |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| miR Scientific | , | Renamed miRNA Scientific |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| Formurex | Stockton, CA | Contract Research |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| NeuroPharm | , | Liquidated 2010 |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| May Health | Paris, France | Ovulation Restoration Therapy |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| Nodality | , | Gone |
| Sharp | Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| , | Website down Feb 2026 - Jul 2026 | |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Tecomet | Bridgeport, MI | CNC Machining, Cutting Instruments, Orthopedics |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Octapharma | Vienna, Austria | Plasma Products |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Biocorp | Issoire, France | Medical Devices |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Radical Numerics | San Francisco, CA | Generative genomics |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| Squarex | , | Gone as of Oct 2021 |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| PhotoSonix Medical | , | Now a licensing outift |
| Onkor Pharma | , | 10 year old company with no product or website |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| PRI Research | , | Renamed Wake Clinical |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| British Biotech | , | Merged into Vernalis 2003 |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Gensco Pharma | Doral, FL | Transdermals |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Newgen Biopharma | , | Suspended trading due to scandal |
| Dundee Cell Products | , | Renamed DC Biosciences |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| Stemnovate | Cambridge, UK | Research Cells |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| Acuvax | , | Pivoted to investments, 2014 |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Merix Bioscience | , | Renamed Dendrix |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| Verana Health | San Francisco, CA | Clinical Database |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Scion Medical Technologies | , | Gone 2016 |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| White Biotech Solutions | , | Shut Down 2019 |
| NovaLead Pharma | Pune, India | Small Molecules |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| NKT Therapeutics | , | Shut down May 2021 |
| Altasciences | Everett, WA | Contract Research |
| Clarivate | London, UK | Vascularized organoids |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| , | Website down Jan 2026 - May 2026 | |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Ribon Therapeutics | , | Shut down May 2024 |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| BioArra | , | Bought by VWR Nov 2016 |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| Rubix Device | , | Website gone, Aug 2017 |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Affigen | , | Liquidating Fall 2019 |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Parker BioConsulting | , | Sole employee is a professional board member |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Gene Express Inc | , | bankrupt? |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| CanSino Biologics | Tianjin, China | Vaccines |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| Kymanox | Morrisville, NC | Life Science Consulting |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| Abogen | Suzhou, China | mRNA |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| , | Renamed Verge Labs, May 2026 | |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| APCRA | , | Shut down 2020 |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| Crown Bioscience | Taicang, China | Drug Development |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Avomeen | , | Acquired by Element, Mar 2021 |
| Tecomet | Kenosha, WI | CNC Machining, EDM, Finishing, Special Processes, Orthopedics, SET, Advanced Surgical |
| , | Website down May 2025 - Dec 2025 | |
| Lupin | Maharashtra, India | Generics |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| , | Renamed Carvolix, Feb 2026 | |
| Dynatherm Medical | , | Shut down 2012 or later |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| , | Website down Jun 2025 - Dec 2025 | |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| Par Health | St. Louis, MO | Generics |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| General Oncology | Brookline, MA | Cancer Therapies |
| Vadovations | , | No info. 2012 SBIR grant |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| Medpace | Cincinnati, OH | Clinical Research |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Phenomix | , | Shut Down 2011 |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Nanostream | , | Closed Mar 2008 |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Neural Analytics | , | Renamed NovaSignal |
| TR Biosurgical | , | Website Taken Over |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| , | Winding down Apr 2026 | |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Texcell | Evry, France | Contract Research |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Immunome | Exton, PA | Cancer Immunotherapy |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| FineHeart | Pessac, France | Heart Failure Device |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| Psomagen | Rockville, MD | Genetic Sequencing |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Viropro | , | Bankrupt 2015 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Ergomed | Raleigh, NC | Clinical Research |
| DM Clinical Research | Houston, TX | Clinical Research |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| Signatur Biosciences | London, UK | PCR Platform |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| Michigan Clinical Research Institute | , | |
| , | Inactive May 2025 | |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| Apath | , | No website update since 2014, Feb 2023 |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Allelix | , | Merged with NPS |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| GSK | Hamilton, MT | Vaccine additive |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| Genmab | Utrecht, Netherlands | Biologics |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| EndoLogic | , | Seems inactive, Aug 2023 |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| IntelliGenome | Houston, TX | CRISPR Diagnostics |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| CorDx | San Diego, CA | Diagnostics |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Mabimmune | , | Merged with Neurimmune |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| AxoTect | , | Phantom company |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Novoresearch | , | Gone 2014 |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| QuantumBio | State College, PA | Protein characterization software |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Protox Therapeutics | , | Now Sophiris Bio |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Dendritix | , | Renamed Argos Therapeutics |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| Baxter | Jayuya, PR | Medication Delivery |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Axium Pharmaceuticals | , | Dissolved |
| Affivant | , | Part of Roivant |
| Clinisys | Tucson, AZ | LIMS Platform |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Texcell | Gronau, Germany | Contract Research |
| Borean Pharma | , | Gone |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| OncoCell MDx | , | Renamed Immunis.AI |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Stablix Therapeutics | New York, NY | Small Molecules |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| TargeGen | , | Bought by Sanofi 2010 |
| Predicine | Hayward, CA | Liquid Biopsy |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Organon (2) | Jersey City, NJ | Women's Health |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| , | Renamed Ladder Bio, Nov 2025 | |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| , | Website taken over May 2026 - Jun 2026 | |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| iCeutica | , | Seems gone, Jan 2022 |
| DxTech | , | Seems gone. No info Dec 2015 |
| Divide and Conquer | , | Website gone Mar 2024 |
| Targenics | , | No website Mar 2020 |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| , | Website down Jan 2026 - May 2026 | |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| Eurosequence | , | Website gone Jan 2020 |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| , | Website taken over Feb 2026 | |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Senzime | Uppsala, Sweden | Devices |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| , | Acquired by Instem, Jul 2025 | |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Qynapse | Paris, France | Imaging Analysis |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| , | ||
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| Activated Cell Therapy | , | Changed name to Dendreon |
| , | No website updates since 2013 as of Dec 2025 | |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Biowarn | , | Gone |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| X-Rx | , | Shut down Jun 2020 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Novosis | , | Acquired by Acino, 2006 |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| Tecomet | Oregon City, OR | Casting, Bone In-Growth Coating |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| , | Acquired by Galecto, Nov 2025 | |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Stago | Maastricht, Netherlands | Diagnostics |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| , | Website down Feb 2026 - Jul 2026 | |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Synosia Therapeutics | , | Acquired by Biotie |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| BenuBiopharma | , | Shut down Sep 2023 |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| SomaLogic | Boulder, CO | Blood Analysis |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| Velcura Therapeutics | , | Website Gone |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Aliri | Loos, France | Contract Mass Spec |
| Avexa | , | Renamed Novita Healthcare |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Target Medicals | , | No news 2016 - Oct 2024 |
| , | Website down Feb 2026 - Jul 2026 | |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Tychan | , | Liquidated early 2022 |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| Jerini | , | Acquired by Shire, 2008 |
| MatTek | Ashland, MA | Cell Products, Services |
| Carcinotech | Roslin, UK | 3D printed tumors |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| |
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| PluriSelect | El Cajon, CA | Cell Separation |
| Pfizer | McPherson, KS | Sterile Injectables |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| , | Website down Dec 2025 - Mar 2026 | |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| , | Merged with ABX-CRO | |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Terumo Medical | Somerset, NJ | Medical Devices |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| Almac | Craigavon, UK | Pharmaceutical Services |
| Noscira | , | Liquidated |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Novo Nordisk | Bohumil, Czech Republic | Diabetes, obesity, liver disease and other therapeutic areas |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| Gerard Biotech | , | Lab supplies, seems defunct |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| SCOLR Pharma | , | Closed Mar 2013 |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| , | Website down Feb 2026 - Jul 2026 | |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Mankind Pharma | New Delhi, India | OTC? |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| SmartCells | , | Bought by Merck Dec 2010 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| Viwit | Shanghai, China | APIs, Formulation |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| Vistin Pharma | Oslo, Norway | Generics |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| Omneuron | , | Closed |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| , | Website down Jul 2025 - Dec 2025 | |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| , | Became part of Accelerator, Dec 2025 | |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| Medicure | Holetown, Barbados | Small Molecule |
| Polpharma | Starogard Gdanski, Poland | Generics |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Western States Biopharmaceuticals | , | Website Taken Over |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Loop Therapeutics | , | Shut down Jan 2021 |
| XellSmart | Suzhou, China | Cell Therapy |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| |
Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| OP2 Drugs | , | Website gone Jan 2020 |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| |
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Celunol | , | Merged with Diversa to become Verenium |
| Invenra | Madison, WI | Antibodies and their derivatives |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| CareDx | Brisbane, CA | Diagnostics |
| Modern Biosciences | , | Renamed Istisso |
| Marical | , | Website Gone |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Bayer | Bergkamen, Germany | Small Molecules |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Enlibrium | , | Gone 2018 |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| , | Website down Feb 2026 - Jul 2026 | |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| , | Website down Dec 2025 - Apr 2026 | |
| Life Analytics Group | , | Gone |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| RegenoCELL Therapeutics | , | Presumed gone |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| CRIO | Boston, MA | eClinical Software |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Derma-Cell Research | , | Website gone Nov 2019 |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Vernacare | Worksop, UK | Surgical Devices |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| Genyous Biomedical International | , | Presumed Gone |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| Hope Medicine | Pudong, China | Antibody Therapy |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| Via Pharmaceuticals | , | Shell Company |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| , | Website down Jan 2026 - May 2026 | |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| Satellos Bioscience | Markham, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| T&T Scientific | , | Website gone May 2023 |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Synedgen | Claremont, CA | Biofilm Control |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Abiologics | Cambridge, MA | Synteins |
| F2G | Cheshire, UK | Antifungals |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| Alderon Biosciences | , | Presumed gone |
| Cerimon Pharmaceuticals | , | Gone |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| , | Website under construction Nov 2025 - Jul 2026 | |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Hansa Medical | , | Renamed Hansa Biopharma |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Affinity Bio | , | Renamed MyriO Tx |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| CereScan Corp | , | Renamed CereHealth |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Kereos | , | Seems gone |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| , | Acquired by Tecan, Aug 2021 | |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Hovione | Hong Kong, China | Contract Manufacturing |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Pneumolabs | , | Dissolved Sep 2018 |
| Veryan Medical | Horsham, UK | Helical Stent |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| Antitope | , | Now part of Abzena |
| Sopherion | , | Website taken over, Mar 2017 |
| , | Website down Sep 2025 - Dec 2025 | |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Amrita Therapeutics | , | Seems gone |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Pulse Biomedical | , | Distributor |
| TranS1 | , | Renamed Baxano Surgical |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Roche | Buonas, Switzerland | Diagnostics |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| Eos Biotechnology | , | Gone 2005 |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| JK Biopharma Solutions | , | Founder gone |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| TransGenRx | , | Bankrupt |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| , | Became part of Accelerator, Dec 2025 | |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Vaccibody | , | Renamed Nykode Therapeutics |
| Narus Development Solutions | , | Gone |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| , | Acquired by Aurinia Pharmaceuticals, Mar 2026; Assets spun out of Onyx Pharmaceuticals | |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| Arbovax | , | Gone |
| Arginox Pharmaceuticals | , | Apparently Gone |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| |
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Absynth Biologics | , | Website Gone Jan 2019 |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Minimus Spine | , | Only real employee now full-time at another company |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Drugabilis | Villejust, France | Druggability Services |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| , | Website down Dec 2025 - May 2026 | |
| , | Website down Nov 2025 - Mar 2026 | |
| EPD Biotherapeutics | , | |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Castor | Claymont, DE | eClinical Trial Software |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Cambria Biosciences | , | Gone Feb 2008 |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| Neurophet | Seoul, Korea | AI-Image Processing |
| Heart Tronics | , | Effectively defunct after scandal |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| , | Pivoted to crypto Jan 2026 | |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| ZyGEM | , | Renamed MicroGEM |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| alphaSyx Therapeutics | , | Gone |
| Oscor | , | Acquired by Integer, Dec 2021 |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| argenx | Boston, MA | Antibody therapies |
| , | Website down Nov 2025 - Apr 2026 | |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Roche | Welwyn, UK | Small Molecules |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Dharma Biomedical | , | Website gone Nov 2022 |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| |
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| , | Website down Aug 2025 - Jan 2026 | |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| Octane Biotech | Lucknow, India | Generics |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Automata | London, UK | Lab workflow automation platform |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| DL Develop | , | Website gone, Dec 2018 |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| CFL Biotech | , | Website gone Jul 2020 |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Angiomics | , | Product being sold by another company |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Zomanex | , | Gone Oct 2019 |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| Luvak Lab | , | Dissolved 2013 |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Regenicin | , | Residential address, three employees, no money |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Point Biomedical | , | Liquidated Jul 2008 |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| UMN Pharma | , | Liquidating Apr 2025 |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| TCG GreenChem | Ewing, NJ | |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| APT Therapeutics | , | Shut down Mar 2019 |
| Synergx | , | Owned by Morphogenesis |
| , | Website down Oct 2025 - Jan 2026 | |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| BiOM | , | Now BionX Medical |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Curexsys | , | Dissolving, Jul 2024 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| Bruker | Billerica, MA | Scientific Instruments |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Otsuka | Rockville, MD | Small Molecules |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| , | Reportedly Closed Mar 2026 | |
| AlcaSynn | , | Renamed ChironWells |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| Promaxo | Oakland, CA | Small form MRI |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| , | Pivoted to blockchain, Sep 2025 | |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Novogene | Beijing, China | Genomic Services |
| JABio | , | Shut Down May 2021 |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| Profusa | Emeryville, CA | Real-time biosensors |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| Heragen | , | Gone |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Novahep | , | Website down, Oct-Dec 2017 |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| , | Merged with Vizgen, Oct 2024 | |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Excaliard | , | Bought by Pfizer 2011 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Scientific Industries | Bohemia, NY | Lab equipment |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| Gerostate Alpha | , | Shut down Dec 2024 |
| Panacos | , | Believe they are inactive |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Norgine | Milan, Italy | Specialty Pharma |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| Afferon | , | Gone, no info |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Gataca | , | Gone |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| NeuroNano Pharma | , | Gone 2018 |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| , | Website down Feb 2026 - Jul 2026 | |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Mabqi | Grabels, France | Antibody Discovery |
| Nereus | , | Website Gone late 2013, no info |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| AGILeBiotics | , | Shut down 2024? |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Acrongenomics | , | No info since 2013, seems gone |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| LabTwin | , | Merged with Labforward |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| BioPointe Scientific | , | Subsumed into parent |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| Synergistix | Sunrise, FL | CRM software |
| Baxter | Marion, NC | Medication Delivery |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Neuro Bio | Oxford, UK | T14 Blocker |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Sonus Pharma | , | Merged with Oncogenex |
| Axplora | Mourenx, France | API manufacturing |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| TransCellular Therapeutics | , | Gone 2019 |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| August Therapeutics | , | Shut down Dec 2024 |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| PharmedArtis | , | Gone 2019 |
| VentriFlo | Pelham, NH | Blood Pumping System |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| Halo Labs | , | Acquired by Waters, May 2025 |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| NantHealth | El Segundo, CA | Diagnostics |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| Qbiogene | , | No website. Fisher sells their products |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| Boston Scientific | St. Paul, MN | Medical Devices |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Fabric Genomics | Oakland, CA | Computational genomics |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| CO.DON | Teltow, Germany | Cell Therapies |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Abcellute | , | Dissolved, Sep 2016 |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Celemics | , | Gone Jul 2018 |
| Qlucore | Lund, Sweden | Visualization Software |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Glialogix | , | Gone Nov 2017 |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| , | Renamed Cordica Medical, Jan 2026 | |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Strides Arcolab | , | Now just Strides |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| QuantaBio | Beverly, MA | PCR equipment |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| ICU Medical | San Clemente, CA | Disposable medical products |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Kate Therapeutics | , | |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Rad AI | San Francisco, CA | Radiology Software |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Riverain Technologies | Miamisburg, OH | Imaging |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Mediatech | , | Now Cellgro |
| Bausch Health | Laval, QC | Small Molecules |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| , | Website down Nov 2025 - Apr 2026 | |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| Diverse Genomics | , | Website gone Jul 2020 |
| Best Vascular Novoste | , | Now Novoste |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Inovio Biomedical | , | Seems gone |
| Lorantis | , | Merged with Celldex 2005 |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| CTK Biotech | Poway, CA | Diagnostics |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| BioVascular | , | 2007 website as of Mar 2019 |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| accuFD | , | Closed Dec 2017 |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Redoxis | Lund, Sweden | Drug development CRO |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Nostrum Laboratories | Kansas City, MO | Generics |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Genedata | Basel, Switzerland | Bioinformatics |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| , | Shut down Jan 2025 | |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| , | Shut down Jan 2025 | |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Cellink | Blacksburg, VA | Bioprinting |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Roche | Schlieren, Switzerland | Small Molecules |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| Protalex | , | Failed 2018, shell |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| , | No news 2015 - Jan 2026 | |
| QC Ware | Paris, France | Molecular Discovery Platform |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| AmProtein | , | Presumed Gone |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| TRIA Bioscience | , | Shut down Aug 2021 |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| LeukoSite | , | Acquired by Millennium 1999 |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| Triangle Insights Group | Durham, NC | Consulting |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| Boston Scientific | Marlborough, MA | Medical Devices |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Bio-Detail | , | Website gone Feb 2023 |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| , | Renamed Cyaris, Apr 2026 | |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| Memento Medicines | , | |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| mAbRx | , | Gone |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Commence Bio | , | Gone 2018 |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| , | Acquired by hVIVO, Jan 2025 | |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| Akrivis Technologies | , | Gone Jun 2021 |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Iconovo | Lund, Sweden | Inhalation Technology |
| IntelligentMDx | , | Shut down Feb 2015 |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| MEDISPECTRA | , | Gone 2002 |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Omeros | Seattle, WA | Small Molecules |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Orthogonal LLC | Chicago, IL | Medical device software |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| Abazyme | , | Dissolved Jun 2017 |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| , | Website down Aug 2025 - Dec 2025 | |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| , | Website down Oct 2025 - Feb 2026 | |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| Tripos | , | Bought by Certara |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| Raze Therapeutics | , | Closed due to complicated biology |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Protypia | , | |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Signalife | , | Renamed Heart Tronics |
| , | Now part of Sanisure, Jun 2026 | |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Sirana Pharma | , | Merged with Apexis Bio |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| , | Renamed Solario Bio | |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| , | Renamed ElisiGen, Dec 2025 | |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| Elona Pharmaceuticals | , | Gone |
| Intrexon | , | Renamed Precigen |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Gentian USA | Moss, Norway | IVD Products |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| Tecomet | Sheffield, UK | Casting, CNC Machining, EDM, Finishing, Forging, Heat Treatment |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| , | Website down Jan 2026 - May 2026 | |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| Axial3D | Belfast , UK | 3D printing for medical use |
| OrthoData | , | Renamed Intellirod Spine |
| MediQuest Therapeutics | , | Gone? |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| CPI Global | , | Website gone Jun 2020 |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| Penwest | , | Bought by Endo |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| InsightRX | San Francisco, CA | Dosing Model |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Parcell Labs | , | Website Gone, Oct 2016 |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| MSD | Ballydine, Ireland | Small Molecules |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| , | Website down Sep 2025 - Dec 2025 | |
| Healx | Cambridge, UK | AI Drug Discovery |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Getinge | Ankara, Turkey | Medical Technology |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| Eisai | Nutley , NJ | Small Molecules |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| SteriTech | Surrey, UK | Process Equipment |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Novita Healthcare | , | Renamed TALi Digital |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Carolus Therapeutics | , | Business revoked in CA |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| Horiba Instruments | Irvine, CA | Equipment |
| DKP Genomics | , | Dissolved Jul 2025 |
| Dorphan | , | Shut down so owner could spend more time skiing |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Alcon | Irvine, CA | Eye-Care Products |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Riboxx | Dresden, Germany | RNA Products |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| , | Website down Jan 2026 - Mar 2026 | |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Olon USA | Concord, OH | Contract Research |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| MikrobEX | , | Renamed Rebiotix |
| Targovax | , | Renamed Circio, Apr 2023 |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| , | ||
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| Nanosonics | Sydney, Australia | Ultrasound |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| CompleGen | , | Shut down Aug 2021 |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Bach Pharma | , | Shut down late 2023 |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Medley Genomics | , | Website for sale Feb 2021 |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Erba MDX | , | Website gone Aug 2019 |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| Axcella Health | , | Renamed Axcella Therapeutics |
| Laborie | Portsmouth, NH | Medical Devices |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| , | Website down Oct 2025 - Feb 2026 | |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| Univfy | Los Altos, CA | IVF reports |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| , | Seems renamed to Lusis Biosciences | |
| WntResearch | , | Shell acquired by Opsy |
| Teva | West Chester, PA | Small Molecules |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| CNS Research | , | Seem gone, 2020 |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Rubicon Research | Thane , India | Generics |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| Haupt Pharma | , | Merged with Aenova |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Recida Therapeutics | , | |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| MicroPort | Arlington, TN | Medical Devices |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Amplyus | , | Renamed miniPCR |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| QInstruments | Jena, Germany | Lab Instruments |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| Cromos Pharma | Portland, OR | Clinical Research |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Bioquanta | , | Gone 2013 |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Rezolute | Redwood City, CA | Biologics |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| , | Website down Jul 2025 - Jan 2026 | |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| Ana-Gen Technologies | , | Gone post 2001 |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| Sinovac Biotech | Beijing, China | Vaccines |
| STX-Med | , | Renamed Cefaly |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Solstice Oncology | , | |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Sonosine | Kidlington, UK | Medical Imaging |
| Promethera Biosciences | , | Renamed Callaion |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Purely Proteins | , | All employees gone, no info |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| VistaMed | , | |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Getinge | Englewood, CO | Medical Technology |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| , | Renamed ABS Bio | |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Antisoma | , | Became investment company |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| Iontas | , | |
| American Drug Co. | , | Renamed Five Star Products |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| Genuine Biosystem | Chennai, India | IVD Products |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Medtronic | Jacksonville, FL | Medical Devices |
| , | Acquired by MasterControl, Mar 2025 | |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| PredxBio | Pittsburgh, PA | Image Analysis |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| , | No news Jan 2021 - Jan 2026 | |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Grunenthal | Aachen, Germany | Small molecules |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| GeneFab | Alameda, CA | Gene Therapy Services |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Axcend | Lehi, UT | Chromatography Services |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Nanobac Pharmaceuticals | , | Gone |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Wacker | San Diego, CA | Biologics CDMO |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| Spherics | , | Bankrupt |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| Sequella | , | Ancient website ©2017, last news 2017 |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| NeoRx | , | Changed name to Poniard, May 2006 |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Optimata | , | Shut down May 2019 |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| AM2PAT | , | Trouble with contaminated products, gone |
| JUVIC | Seoul, Korea | Microneedle Technology |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Tecomet | Oregon City, OR | Contract Medical Device Work |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Clontech | , | Now Takara Bio |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Genetic Technologies Group | , | Renamed geneType |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| Boehringer Ingelheim | Shanghai, China | Small Molecules, Biologics, CDMO |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Biovail | , | Merged with Valeant |
| Quellthera | , | Subsumed into Liveleaf |
| Comac Medical | Sofia, Bulgaria | European CRO |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| Relevant Bio | , | Shut Down Oct 2023 |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Calyx Pharma | Mumbai, India | APIs |
| , | Acquired by Lonza, Apr 2017 | |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| United Neuroscience | , | Renamed Vaxxinity |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| , | Acquired by Inizio, Dec 2025 | |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Altasciences | Montréal, QC | Contract Research |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Glenmark | Mumbai, India | Generic Small Molecules |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| ConquerX | , | Dissolved Jun 2021 |
| Gilead | Mississauga, ON | Small Molecules |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| Anacura | Evergem, Belgium | Analytical |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| BioLegacy Research | San Diego, CA | Contract Research |
| , | Renamed Indero | |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| Altravax | , | Shut down 2016 |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| Aztech Sciences | , | Website gone Jun 2021 |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Dante Labs | , | Seems to be Dante Genomics now |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| XW Laboratories | , | Renamed XWPharma |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| DNALite Therapeutics | , | Renamed Particella |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| |
Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Venebio | Glen Allen, VA | Consultants |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| , | Website down Oct 2025 - Feb 2026 | |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| BIND Biosciences | , | Now BIND Therapeutics |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Innerpulse | , | Gone maybe 2013 |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Precision Research Institute | , | Shut down Apr 2024 |
| , | Company gone Nov 2023, website taken by a game | |
| , | Website down May 2025 - Nov 2025 | |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Acucela | , | folded into Kubota Vision |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| EpicGenetics | , | Seems gone Jan 2024 |
| M2 Medical | , | Now Asante Solutions |
| , | Website down, COO gone Oct 2025 | |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Affinimark Technologies | , | Gone |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| , | Renamed Hubot, May 2026 | |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| VieVax | , | Gone Jan 2007 |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Nova Biomedical | Norwood, MA | Lab instruments |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| Stromedix | , | Bought by Biogen Idec 2012 |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| Rezo Therapeutics | San Francisco, CA | |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| Boston Scientific | Cork, Ireland | Medical Devices |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Website down Dec 2025 - Jun 2026 | |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Lupin | Goa, India | Generics |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| Active Implants | , | Renamed NUsurface |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| DanPET | , | One guy, Feb 2024 |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Bicolor | Belfast, UK | Lab Assays |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Arzeda | Seattle, WA | Computation protein design |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| Noucor Health | Barcelona, Spain | Small Molecules |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| , | Gone Mar 2024 | |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| , | Acquired by hVIVO, Dec 2019 | |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Genova Clinical Research | , | Gone, 2014 |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| GNA Biosolutions | , | Now part of HP Health |
| , | Website down Oct 2025 - Jan 2026 | |
| Wellinks | New Haven, CT | Portable Nebulizer |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Baxter | Grosotto, Italy | Medication Delivery |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Eternans | , | Shut down Jul 2022 |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| , | Website gone Jan 2026 - Jul 2026; fka Sun BioPharma | |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| GlycoEra | Newton, MA | Custom Glycan Platform |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| IR2Dx | , | Gone, 2019 |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Barrier Therapeutics | , | Bought by Stiefel |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| vTv Therapeutics | High Point, NC | Small molecules |
| Calchan | , | Shut down Dec 2020 |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| ProPharma Group | Raleigh, NC | Consulting |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| PharmaGap | , | Shut down 2013 |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| NovoKera | , | Merged into Longevity Biomedical |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Aadigen | , | Renamed Aanastra |
| , | Shut down Jan 2024 | |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| , | Website down Jan 2026 - May 2026 | |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Immerge BioTherapeutics | , | Founded 2000 |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Imstem Biotechnology | , | Website gone May 2021 |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Apharm | , | Now Biofarma Group |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| Mindshare Medical | , | Renamed RevealDx |
| BioParadox | , | Shut down Dec 2017 |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| ResVerlogiX | Calgary, AB | Small Molecules |
| HCW Biologics | Miramar, FL | Immunotherapy |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Spring Discovery | , | Renamed Spring Science |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Crown Bioscience | Beijing, China | Drug Development |
| Inexia | , | Acquired by Centessa |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Chrysalis | Waltham, MA | GMP Space |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| Calypte Biomedical | , | Gone |
| Oncovista | , | Dormant 2016 |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| CRI | , | Now BiomericsATL |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Chanelle Pharma | Amman, Jordan | Generics |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| , | Website down Oct 2025 - Jan 2026 | |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| Insamo | , | |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Novotech | Hong Kong, China | Clinical Research |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| , | Website down Oct 2025 - Feb 2026 | |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| Zai Lab | Hong Kong, China | Small Molecules |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| ActoBio Therapeutics | , | Brought into Precigen |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| Grunenthal | Quito, Ecuador | Small molecules |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Mologen | , | Liquidating, May 2020 |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| , | Website down Feb 2026 - Jul 2026 | |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Epiomed Therapeutics | , | Gone |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| , | Website down Oct 2025 - Feb 2026 | |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| TaiwanBio | , | Website gone Oct 2021 |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| , | Website down Jun 2025 - Dec 2025 | |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| , | Shut down Sep 2025; fka GenoFAB | |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Tyrian Diagnostics | , | Gone 2012 |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| MacuClear | , | Website gone Jan 2019 |
| CytoMol (2) | , | SF-based, Looks gone |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| Totient | , | Acquired by Absci, Jul 2021 |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| Newormics | , | Renamed vivoVerse, late 2022 |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| hVIVO | London, UK | Viral Services |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Healionics | Seattle, WA | Biomaterials for devices |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| A2IDEA | , | Only employee left Jan 2024 |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Centinel Spine | West Chester, PA | Spinal Implants |
| MindWalk | Victoria, BC | Custom Antibodies |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| Apoptos | , | Acquired by Receptos |
| Sanovel | Silivri, Turkey | Generics |
| , | Now PamDx, May 2026 | |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| Bayer | Bitterfeld, Germany | Small Molecules |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| , | Shut down Mar 2026 | |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| NeuroproteXeon | , | Gone 2021 |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Medion Diagnostics | , | Bought by Grifols? |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| Masy Systems | , | fka Masy Biosystems |
| Neurogene | Houston, TX | Genetic Therapies |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| NeuroVasx | , | No website May 2019, founded 1997 |
| , | Part of Genesis | |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| imarc | , | Acquired by Avania, Jun 2021 |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| Nano Oncology | , | Gone |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| , | Website down Jul 2025 - Mar 2026 | |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| ClinArt | , | Now ClinArt MENA |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| , | Gone Sep 2025 | |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| StromaCyte | , | Small time, no info. Defunct |
| Orbus Pharma | , | Website Gone |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| Pharmanovia | London, UK | Acquisition of Drugs |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| Nile Therapeutics | , | Merged with Capricor |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| , | Website down Jan 2026 - May 2026 | |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| , | Renamed BreezeBio, Feb 2026 | |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Scientia Advisors | , | Website gone Jul 2015 |
| Crown Bioscience | Loughborough , UK | Drug Development |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Ascelegen | , | Closed |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| , | Renamed Valion Bio, Apr 2026 | |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| , | Website down Jan 2026 - May 2026 | |
| OmniBiome Therapeutics | , | Gone 2014? |
| Ergomed | Cologne, Germany | Clinical Research |
| Sixal | , | SBIR, Presumed defunct |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| IncellDx | , | Renamed HealthBio AI |
| Mojave Therapeutics | , | Gone |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Synakis | Toronto, ON | Ocular Delivery Hydrogel |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| , | Acquired by StarFish Medical, Nov 2024 | |
| Paige | New York, NY | AI Pathology |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Hemadvance | , | Gone |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| Niramai | London, UK | AI-breast cancer detection device |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| Elixir Medical | Milpitas, CA | Stents |
| , | Renamed Helyx Industries | |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| CoRegen | Houston, TX | Genetically Engineered T Reg Cells |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Confer Health | , | Shut down 2021 |
| , | Merged with Nova Biomedical | |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Synlab | Munich, Germany | Clinical Lab Services |
| Remo CRO | , | Seems to be rebranded as Supeira |
| BioConsulting International | , | Ancient website, presumed defunct |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| Diagast | Loos, France | Transfusion Reagents |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Elypta | Solna, Sweden | Liquid Biopsy |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Alizyme | , | Bankrupt 2009 |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| HEC | , | Website down Dec 2024 - May 2025 |
| Kastle Therapeutics | , | Closed May 2018 |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Spiden | , | Renamed Liom, Jul 2024 |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| Hua Medicine | Shanghai, China | Small Molecules |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| , | Website down Jul 2025 - Nov 2025 | |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| , | Website down Jan 2026 - May 2026 | |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| Pharmexa | , | Merged into Affitech, May 2009 |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Jenken Biosciences | , | Shut down by 2014 |
| Pharminox | , | Website gone, Aug 2017 |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| , | Website down Sep 2025 - Dec 2025 | |
| Biomax Informatics | , | Acquired by Labvantage |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Cala Health | San Mateo, CA | Neurological Device |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Crown Bioscience | San Diego, CA | Drug Development |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Metamark Genetics | , | Shut down 2018 |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| Veeva Systems | Toronto, ON | Life Science Software |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Saniona | Glostrup, Denmark | Small Molecules |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| bioMerieux | Cambridge, MA | Diagnostics |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| , | Website down Dec 2025 - Apr 2026 | |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| LinaTech | Suzhou, China | Cancer treatment device |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Prommune | , | |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Vega Therapeutics | , | Acquired by Incyte, Jul 2026, $1.25B; Part of Star Therapeutics |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Proteonomix | , | Shell Company |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Stada | Belgrade, Serbia | Generics |
| NextPharma | Limay, France | Contract Research & Development |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| AltaRex | , | Gone |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| , | No news 2019 - Apr 2026 | |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| preclinics | Parma, Italy | Contract Research |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| NeuroRepair | , | Business revoked by CA, 2007 |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Galileo Research | , | No news since 2012, presumed gone |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| Cytiva | Amersham, UK | Medical Devices |
| SelectX | , | Website hacked; No updates since 2011 |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Zai Lab | Suzhou, China | Small Molecules |
| , | Website down Jul 2025 - Dec 2025 | |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| AptaIT | , | Website gone and for sale Nov 2019 |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Telis Bioscience | , | Renamed Alvea |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| bioMerieux | Durham, NC | Diagnostics |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| VedaLab | Cerisé, France | IVD rapid tests |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| |
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Valor Biotechnology | , | Renamed Roivant |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| EcoSurg | , | Shut Down May 2017 |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Verenium | , | Bought by BASF, Dec 2013 |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| Smart Biosciences | , | Renamed sb-Peptide |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| , | Renamed Entirety Biomedical | |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| BioMS Medical | , | Gone? |
| , | Closed June 2024 | |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Parexel | Newton, MA | Clinical Research |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Profil | Neuss, Germany | Clinical Research Services |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| MedGyn Products | Westmont, IL | OBG Devices |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Catamaran Bio | , | Winding down Jan 2024 |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| , | Acquired by Sensei Biotherapeutics, Feb 2026, took name Jun 2026 | |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Aimmune Therapeutics | , | |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| AntiOp | , | Tech sold Jun 2015 |
| Cdymax | Bangalore, India | APIs |
| Delpor | Brisbane, CA | Drug Delivery System |
| PeriCor Therapeutics | , | Website Gone |
| Synaptrix | New York, NY | Brain-Computer Interface |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| Cell Matrix | , | Acquired by Cancervax |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Divergence | , | Bought by Monsanto |
| Greppo Technologies | , | Renamed Verix Health |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Tecomet | Woburn, MA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| BioXpert | , | Website gone Mar 2017, employees gone |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| , | Website down May 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Gentegra | , | Part of IntegenX |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Yposkesi | , | part of SK pharmteco |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| Effipharma | , | Marked as closed by Google |
| XellSmart | Shanghai, China | Cell Therapy |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Accium BioSciences | , | Shut down Oct 2024 |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Unither Pharmaceuticals | Paris, France | CDMO |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| Avexxin | , | Rebranded as Coegin Pharma |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| NanoTess | Calgary, AB | Biocatalysts |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Abbott | Altavista, VA | Nutrition |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| , | No news 2021 - Jun 2026 | |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| Lifebit | London, UK | Genetic Data Analysis |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| BioSyntech | , | Bought by Piramal |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| OrphoMed | , | Shut Down 2022 |
| Velquest | , | Bought by Accelrys Jan 2012 |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Santen | Osaka, Japan | Ophthalmics |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| rhealth | Bedford, MA | Diagnostics |
| , | Website down Jun 2025 - Oct 2025 | |
| Prochon Biotech | , | Acquired by Histogenics |
| , | Website down Feb 2026 - Jul 2026 | |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Delpharm | Evreux, France | Contract Manufacturing |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| SRI International | Menlo Park, CA | Independent Research |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| , | Website down Nov 2025 - Apr 2026 | |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Septerna | South SF, CA | GPCR Drug Discovery |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| , | Website down Feb 2026 - Jul 2026 | |
| Ileo Science | , | Seems gone Mar 2022 |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Niowave | Lansing, MI | Radioisotopes |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| Lux Biosciences | , | Gone |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Znomics | , | Bankrupt, Shell Company Now |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Adroit Surgical | , | Defunct |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Rallybio | New Haven, CT | Therapeutics |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| , | Renamed LeonaBio, Jan 2026 | |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| IVAX Corporation | , | Acquired by Teva 2006 |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Boca Pharmacal | , | Bought by Qualitest |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Grannus Biosciences | , | Gone |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| PathoGene | , | Website taken over, Oct 2017 |
| TherOptix | , | No website Oct 2021 - May 2023 |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| , | Website down Feb 2026 - Jul 2026 | |
| PeriGen | Cary, NC | Perinatal Devices |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| PolyTherics | , | Joined Antitope to become Abzena |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| Essential Pharma | Egham, UK | Generics |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| MeiraGTx | London, UK | Gene Therapy |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| Rapalogix Health | New York, NY | TORC1 inhibitors |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| Intercytex | , | Liquidated |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| RheoSense | San Ramon, CA | Viscometers |
| , | Shut down June 2024 | |
| Quentis Therapeutics | , | Shut down late 2020 |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Ansata Therapeutics | , | Out of business 2007 |
| Breathometer | , | Product didn’t work, pivoted |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| , | Acquired by Novacyt Group | |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Solvay | , | Bought by Abbott 2010 |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| , | Acquired by QOL Medical, Nov 2025 | |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| Dynacare | , | Bought by LabCorp 2002 |
| AIBioTech | , | Assets auction, Aug 2017 |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Conkwest | , | Website gone Dec 2015 |
| PsiOxus Therapeutics | , | |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| , | Acquired by Eli Lilly, Jun 2026, up to $300M | |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| Cureport | Worcester, MA | Nanomedicines |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| yuFlu | , | No website, no info Feb 2021 |
| , | Website down Jul 2025 - Dec 2025 | |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| , | Website down Feb 2026 - Jul 2026; aka Integrity Implants | |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| Promosome | , | Gone |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| bespark*bio | Vienna, Austria | Consulting |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Belyntic | Berlin, Germany | Immunotherapies |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| Catalyz | , | Gone |
| KXT bio | , | Shut down 2019 |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| Apaxis Medical | , | Gone 2019 |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| MediWound | Yavne, Israel | Wound & Burn Care |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Theranostech | , | Renamed Sandia Biotech |
| Eargo | San Jose, CA | Hearing Aids |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| NeurOptics | Irvine, CA | Pupillometry |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Avail Medsystems | , | Tech sold Mar 2024 |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Cedilla Therapeutics | , | Shut down May 2023 |
| Eccogene | Shanghai, China | Small Molecules |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| , | Shut down May 2026, assets to Innoviva | |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Tigris Pharmaceuticals | , | Now Kirax |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Percivia | , | Shut Down 2012 |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Accellacare | Downers Grove, IL | Clinical Research |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| AC Diagnostics | , | Website from 2004 |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| , | Website down Dec 2025 - Apr 2026 | |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| Tecomet | Santa Ana, CA | Orthopedics CNC Machining |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Regenica Biosciences | , | Gone Nov 2020 |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| E3X Bio | , | Shut Down Mar 2019 |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| Zivena | , | Gone |
| NS Pharma | Paramus, NJ | Small Molecule |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| , | Merged with Vaxanix | |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| , | Pivoted to food, Feb 2026 | |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| Attralus | Naples, FL | Amyloidosis Treatments |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Kylin Therapeutics | , | Sold |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Sepiatec | Berlin, Germany | Separation Systems |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| Sytera | , | Merged with Sirion Aug 2006 |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| AngioChem | , | All employees gone, no info, presumed gone |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| PluriCell | , | Renamed LizarBio |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Zuma Biosciences | , | Company Gone |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| , | Acquired by Bruker, Sep 2020 | |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| mibe Arzneimittel | Brehna, Germany | Generics |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| BaseCure Therapeutics | , | |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| , | Website down Aug 2025 - Jan 2026 | |
| Bafna | Chennai, India | Generics |
| , | Website down Dec 2025 - Jun 2026 | |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| AxioMed | , | President left in 2018, not registered in MA |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| Novonesis | Paraná, Brazil | Enzymes |
| RelonChem | Cheshire, UK | Generics |
| Protein Polymer Technologies | , | Basically Gone |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| , | Part of Evogene | |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| Elegen | San Carlos, CA | DNA writing |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Karo Bio | , | Renamed Karo Pharma |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Aug 2025 - Jan 2026 | |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| Lavipharm | Paris, France | Small molecules |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Virvio | , | Gone Feb 2020 |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Chaperone Therapeutics | , | Gone 2019 |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Proteintech | Rosemont, IL | Research Antibodies |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| PhoreMost | Cambridge, UK | Biologics |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics, CDMO |
| Tirupati | New Delhi, India | Generics |
| Gran Med | , | Gone |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Epigenesis Pharmaceuticals | , | Gone |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Therorna | Beijing, China | RNA Therapies |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Therabest | Seoul, Korea | iPSC |
| Medrobotics | , | Bankrupt Jun 2022 |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Collgard Biopharmaceuticals | , | Gone |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Amachumu Bio | , | Shut down April 2021 |
| Vernacare | Newtown, UK | Surgical Devices |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Acrux | West Melbourne, Australia | Drug Delivery |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Gentel Bio | , | Ceased Operations 2012 |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| , | Website down Jun 2025 - Dec 2025 | |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| SolaranRx | , | Website taken over |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| O-Ray pharma | , | Inactive Jun 2022 |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
 |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Medispect | , | Shut Down 2013 |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Vision Medicines | , | Gone 2017 |
| Gene Signal | , | Bankrupt, Apr 2021 |
| GliaMed | , | Website copyright 2009, seems defunct |
| Sanofi | Reading, UK | Small Molecules |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| , | Website down Jul 2025 - Jan 2026 | |
| CombiGene | , | Stopped research Jan 2025 |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Algenix | , | MN Business revoked, Mar 2004 |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Pangenetics | , | Bought by Abbott |
| Abbott | Longford, Ireland | Diagnostics |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Ingenix | Warsaw, Poland | AI Engine Connection |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| CytoLogix | , | Gone, Sep 2012 |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| Santen | Osaka, Japan | Ophthalmics |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Natera | San Carlos, CA | Prenatal Testing |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Gen Plus | Munich, Germany | Formulation |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| Hybrigenics Services | , | Renamed ATON Group |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| Niche Generics | Hitchin, UK | Contract Generics |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Daktari Diagnostics | , | Gone 2017 |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| , | Website down Oct 2025 - Feb 2026 | |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Abbott | Sylmar, CA | Device Manufacturing |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Vanadis Laboratories | , | Gone 2018 |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| , | Website down Aug 2025 - Jan 2026 | |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| AstronauTx | London, UK | Alzheimer's Treatments |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Minntech | , | Now Medivators |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Pear Bio | London, UK | Cancer Treatment Selection |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Benchling | San Francisco, CA | Biotech Software |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Aytu BioScience | , | now Aytu BioPharma |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| TETmedical | Fair Haven, NJ | Nanomedicine company focused on in vitro diagnostics |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| AGI Therapeutics | , | Bought by Videra |
| , | business filings late Oct 2023 - Oct 2025 | |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| Locanabio | , | Shutting down late 2023 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| ImmunoBiochem | , | No news 2018 -2023 |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| , | Website down Jan 2026 - May 2026 | |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| , | Pivoted to Crypto, Oct 2025 | |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| , | One person, possibly moved to AK | |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Wacker | Halle, Germany | Biologics CDMO |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| AsymBio | Jinshan, China | Biologics CDMO |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Quench Bio | , | Wound down Mar 2021 |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| ARCBio | , | Shut down 2014 |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| |
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Genomadix | Kanata, ON | Portable PCR |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| Proteintech | Manchester, UK | Research Antibodies |
| Sanofi | North York, ON | Biologics, Vaccines |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| ImmuRx | , | Gone, not sure what happened |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| , | CEO left 2020, still on website Dec 2025 | |
| , | Acquired by Certara, Oct 2024 | |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| , | Website down Jan 2026 - Apr 2026 | |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Chroma Medicine | , | |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Imeka | Sherbrooke, QC | Neuroimaging |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| TAI Diagnostics | , | Gone |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| Salvat | Miami, FL | Small Molecules |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| , | Website down Feb 2025 - Dec 2025 | |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| DDL | Edison, NJ | Device Testing |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| , | ||
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Delpharm | Orléans, France | Contract Manufacturing |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| StemBioSys | San Antonio, TX | Stem Cells |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Accellacare | Winston-Salem, NC | Clinical Research |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Cytel | Pune, India | Clinical software, statistical services |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| , | Now part of Exalta | |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Validant | , | Renamed Eliquent Life Sciences |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| Cira Discovery | , | Website copyright 2003 |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| Almirall | Barcelona, Spain | Small Molecules |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Faze Medicines | , | Shutting down Nov 2022 |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| Coral Drugs | New Delhi, India | APIs |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| Catalent | Winchester, KY | Contract Manufacturing |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Valitor | Berkeley, CA | Protein therapeutics |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| Sinusys | , | Shut down 2023 |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| , | Website down Jul 2025 - Dec 2025 | |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| Perlara PBC | , | Shut down Feb 2019 |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Intellimedix | , | Company founder/employee all moved on |
| Enterin | , | Website taken over Feb 2025 |
| MeDiNova Research | , | Now part of Accelacare |
| Kiecana Clinical Research | , | Now KCR |
| Pathway Genomics | , | Renamed OmeCare |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Constantiam Biosciences | Houston, TX | Clinical Interpretation Software |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| South Coast Clinical Trials | , | Website gone |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| TheraLogics | , | Been around since 2008, but no site or current info |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| XBiotech | Austin, TX | Antibody Therapy |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Novotech | Sydney, Australia | Clinical Research |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| Immunogen (1) | , | Renamed ImmunogenX |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| Avaxia Biologics | , | IP acquired by Circle33 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| OraPharma | , | Owned by Valeant |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| , | part of ElevateBio; fka LifeEDIT | |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Ergomed | Moscow, Russia | Clinical Research |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| Retroscreen Virology Group | , | Renamed hVIVO |
| , | Acquired by Bio-Techne, Apr 2021, $215M + $105M milestones | |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Altasciences | Laval, QC | Contract Research |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Stryker | Salt Lake City, UT | Medical Devices |
| Genyro | San Francisco, CA | DNA Construction Technology |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| , | Website down Feb 2026 - Jul 2026 | |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Integer | Plano, TX | Medical & Surgical Devices |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Groove Biopharma | , | Gone 2015 |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| JAJ International | , | Website not working, redirecting strangely |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| , | Renamed Kapadi, Nov 2025 | |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| , | Website down Sep 2025 - Dec 2025 | |
| Auris Medical | , | Renamed Altamira Therapeutics |
| Zetra Biologicals | , | Gone |
| SE3D | , | Renamed Seed Therapeutics |
| Iproteos | , | Products now with Accure Therapeutics |
| XRlabs | Albacete, Spain | Surgical Intelligence, Visualization |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Cordis | Miami Lakes, FL | Medical Devices |
| PreciThera | , | Website taken over, Dec 2021 |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Endotis Pharma | , | Founded in 2003. No info |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| , | Acquired by Xoma, Oct 2025 | |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Wyeth | , | Bought by Pfizer |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| Xegen | Gemenos, France | NGS Data Analysis |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Navinta | Ewing, NJ | Generics |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| , | ||
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Vesper Medical | Wayne, PA | Venous Stent |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| Alexis Biotech | , | Dissolved May 2015 |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| Leucid Bio | London, UK | Cell Therapy |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| , | Website down Oct 2025 - Jan 2026 | |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| Eurogentec | Seraing, Belgium | Biologics |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| Oncogen | , | Acquired by BMS, 1986 |
| NeurAegis | , | Seems gone, Sep 2022 |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Santen | Osaka, Japan | Ophthalmics |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Allez Health | Carlsbad, CA | Biosensors |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| JustRight Surgical | , | Renamed Bolder Surgical |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| Alltrna | Cambridge, MA | tRNA therapies |
| PKPD International | , | Attack website |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| Altasciences | Scott Township, PA | Contract Research |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| IQVIA | Lenexa, KS | Clinical Research |
| , | Website down Jul 2025 - Jan 2026 | |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Oligasis | , | Changed named to Kodiak Sciences |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| Norac Pharma | Azusa, CA | API Manufacturing |
| inDNA Research Labs | , | Shut down 2015 |
| , | Seems unserious, Jul 2026; fka Cetazam Therapeutics | |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Coeptis | , | |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| ChemRegen | , | Seems gone Jan 2022 |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Simbex | Lebanon, NH | Biomechanical devices |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| CohBar | , | Shut down, late 2023 |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| neoSurgical | , | Shut down 2017 |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| XStalBio | , | Folded |
| MediLink Therapeutics | Suzhou, China | ADC |
| Verasonics | Kirkland, WA | Research Ultrasound |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| Genlantis | , | Acquired by AMSBIO |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| , | Acquired by GNI Group, Jun 2026 | |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| MSD | Leopardstown, Ireland | Small Molecules |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| Lusochimica | , | Owned by Menarini |
| Integer | Trenton, GA | Medical & Surgical Devices |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| Inference | Pune, India | Clinical Trial Services |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| Xyntek | , | Segment of non-life science business |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| GenEscence | , | Gone Jul 2013 |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| Cytochroma | , | Acquired by Opko Health |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| Terapio | , | Website Gone, Sep 2020 |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| Altair Therapeutics | , | Shut down Feb 2011 |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Akermin | , | Closed |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| iKaryos Diagnostics | , | Gone |
| , | Acquired by Frontage, Jul 2021 | |
| Pervasis | , | Bought by Shire, Sep 2009 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Galaxy Biotech | , | Shut down Feb 2008 |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Verici Dx | Cardiff, UK | Kidney Transplant Technology |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| , | Website down May 2025 - Dec 2025 | |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Korio | Doylestown, PA | RTSM Platform |
| Amorsus | , | Website Gone 8-30-13 |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| SilaGene | , | Gone |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Medtronic | North Haven, CT | Medical Devices |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| AniLocus | Germantown, MD | Preclinical CRO |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| , | Part of Genesis Biotechnology Group | |
| Novarad | Provo, UT | Imaging Software and Technology |
| , | Shut down 2024 | |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Aerovance | , | Gone, don’t know where |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| , | Website down Sep 2025 - Dec 2025 | |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Ipsen | Dublin, Ireland | Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| AddBIO | , | Gone Oct 2023 |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| , | Website down Nov 2025 - Apr 2026 | |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| MyoSyntax | , | Gone 2021 |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Inspirata | Tampa, FL | Cancer Insights |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| Enci Therapeutics | , | No website, business suspended by NC |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Aixlie Pharmaceuticals | , | No idea what happened |
| Bioxene | , | Website gone, Company Presumed gone |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Renamed Medici Therapeutics, Dec 2024 | |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Accumed Systems | , | Dated website, cant find any employees |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| SomaServe | , | Renamed ViaNautis Bio |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Bakhu Pharma | , | Bankrupt, location sold |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| BA Sciences | Salem, NH | Analytical Services |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Acumed | Hampshire , UK | Medical Implants |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| NeuroTransit | , | Behind on taxes in CA |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| Zelos Therapeutics | , | No site |
| ViroPharma | , | Bought by Shire Jan 2014 |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| Salvat | Barcelona, Spain | Small Molecules |
| , | Website down Dec 2025 - Apr 2026 | |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| Purinomia Biotech | , | |
| NeurAxon | , | No updates since 2008 |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| Sanofi | Paris, France | Small Molecules |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| HebeCell | Natick, MA | Cell Therapies |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| iWel | Exton, PA | Glucose Meters |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Metenova | ZZ, Sweden | Mixers |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Patrin Pharma | Skokie, IL | Generics |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| , | Website down Feb 2026 - Jul 2026 | |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| Pivotal BioSciences | , | Shut down late 2018 |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| Semafore Pharmaceuticals | , | Gone? |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Stada | Bad Vilbel, Germany | Generics |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Integer | Chaska, MN | Medical & Surgical Devices |
| Protein Design Labs | , | Renamed PDL Biopharma |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| , | ||
| Roche | Tucson, AZ | Diagnostics |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| CSSi | , | |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Bio-ops | , | Now SVA |
| Helix | San Mateo , CA | Genetic Testing |
| Ocean Therapeutics | , | Shut down June 2013 |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Silktap | , | Liquid silk. Site gone |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| , | Website down Oct 2025 - Jan 2026 | |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| Xenikos | , | Shut down early 2023 |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Angiosyn | , | Acquired by Pfizer 2005 |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Axial Biotech | , | Closed Mar 2013 |
| Hybrigenics | , | Renamed ATON |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| AB Science | Paris, France | Small Molecules |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Qualicaps | Whitsett, NC | Capsules |
| Helsinn | Iselin, NJ | Small Molecules |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Aranscia | Houston, TX | Diagnostic Software |
| Biorelate | Manchester, UK | AI Data Curation |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Alkermes | Waltham, MA | Small Molecules |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Biotechnical Services | , | Shut down Apr 2019 |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| ARTham Therapeutics | , | Shut Down late 2023 |
| , | No news 2020 - Dec 2025 | |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| Ipsen | Signes, France | Small Molecules, Biologics |
| LunaDNA | , | Shutting down Jan 2024 |
| Prognosys Bioscience | , | 10 years in stealth mode |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Medicure | Winnipeg, MB | Small Molecule |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| , | Bankrupt May 2025 | |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| BioVersys | Basel, Switzerland | Drug Discovery |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Myoposity Therapeutics | , | Gone |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| Nascent Biologics | , | Changed to Nascent Biotech |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Ceptyr | , | Out of business 2012 |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Solventum | Eagan, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| , | Website down Aug 2025 - Jan 2026 | |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| OpenClinica | Needham, MA | Clinical Study Software |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| , | Acquired by HiRO, Aug 2023 | |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Life Couriers | Munich, Germany | Diagnostics |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Aracea Therapeutics | , | No website Aug 2022 |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Davol | , | Acquired by Bard, 1980 |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Ultragenyx Pharmaceutical | South SF, CA | Small Molecules, Biologics |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| Novotech | Taipei, Taiwan | Clinical Research |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| , | Acquired by mining company; fka Anew Medical | |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| NEC Oncoimmunity | , | Renamed NEC |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| Androclus Therapeutics | , | Closed, May 2007 |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| Satoris | , | Bought by Rules-Based Medicine |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| Pall | Port Washington, NY | Filtration |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Excalipoint Therapeutics | Shanghai, China | Cell Therapy, Antibodies |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Spriaso | , | No news 2019 - May 2025 |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| Santen | Nara, Japan | Ophthalmics |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| ERT | , | Renamed Clario, Nov 2021 |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| , | Website down Sep 2025 - Feb 2026 | |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Synomics | , | Now Smithers Pharma Services |
| ADispell | , | Website gone Apr 2018 |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Hepalink | Shenzhen, China | Heparin API |
| Nizyme | , | Gone Jul 2015 |
| Hydra Biosciences | , | Website gone Mar 2019 |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Chesapeake Biological Labs | , | Now known as Cangene |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| , | Website down Nov 2025 - Apr 2026 | |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Phenomyx | , | Gone Jun 2019 |
| Tensys Medical | , | Website gone Sep 2017 |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| Immutics | , | Renamed TrueBinding |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Astek Diagnostics | Baltimore, MD | UTI Diagnostic |
| Microislet | , | Bankrupt 2008 |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| Alkermes | Wilmington, OH | Small Molecules |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Convergen | , | |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Novotech | Shanghai, China | Clinical Research |
| Gene ID inc | , | Website taken over |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| TTP Labtech | , | Renamed SPT Labtech |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| BioDot | Irvine, CA | Equipment |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| Angel Biotechnology | , | Bankrupt, 2013 |
| OvaGene Oncology | , | Gone Feb 2020 |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Biowest Therapeutics | , | Website Gone |
| Dirui Industrial | Changchun, China | Automated Assays |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| Delpharm | Reims, France | Contract Manufacturing |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| VytronUS | , | Shut down Mar 2020 |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| Accellix | Jerusalem, Israel | On-demand Assays |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| , | Acquired by Bruker, May 2024, €870M | |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Topivert | , | Liquidating Jan 2021 |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Denk Pharma | Munich, Germany | Generics |
| Lacer | Barcelona, Spain | Small Molecules |
| New Brunswick Scientific | , | Merged into Eppendorf |
| TG Therapeutics | Morrisville, NC | Biologics |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Quratis | Cheongju, Korea | Vaccines |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Sharp | Bethlehem, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Website down Jun 2025 - Dec 2025 | |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Glide Pharma | , | Renamed Glide Technologies |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| SEQENS | Pune, India | Analytical method validation, API development |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Regis Chromatography | Morton Grove, IL | Synthesis & Separations |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| GIVAX | Boston, MA | GI Vaccines |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| 76Bio | , | Shut down Jan 2025 |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| ApniCure | , | Gone 2017 |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| Pharmaron | Xi'an, China | R&D Services |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Ginkgo Bioworks | Boston, MA | Autonomous Labs |
| Manhattan Pharmaceuticals | , | Gone |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| , | Acquired by Canoa, Aug 2019 | |
| Vista Scientific | , | Shut down Dec 2015 |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| Axxam | Milan, Italy | Drug discovery services |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| PepLib Biotech | ZhuZhou, China | Peptides |
| , | Shut down Feb 2026 | |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| , | Website down Jul 2025 - Jan 2026 | |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| MedinCell | Jacou, France | API Delivery Gel |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Ergomed | Zagreb, Croatia | Clinical Research |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Persomics | , | Gone 2019 |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Coordination Therapeutics | , | Not Active |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Genencor | , | Bought by DuPont |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Global Cell Solutions | , | Gone Apr 2018 |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| genOway | Lyon, France | Rat and cell models |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| Metrad Biosystems | , | Website gone |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| America Stem Cell | , | Changed name to Targazyme |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| Tecomet | Memphis, TN | Bone In-Growth Coating |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| Ergomed | Madrid, Spain | Clinical Research |
| HarkerBIO | , | Shut down Apr 2019 |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| , | No news Mar 2021 - Jan 2026 | |
| PathAI | Boston, MA | AI Powered Pathology |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| VM Discovery | , | 20 yr old company with no info on website |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| BioVolutions | , | Gone |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Medtronic | Warsaw, IN | Medical Devices |
| BalinBac Therapeutics | , | Gone 2018 |
| OxOnc Development | , | Website gone Apr 2018 |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Omniseq | , | Acquired by LabCorp, 2021 |
| Endomag | Cambridge, UK | Biopsy Tracer |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| SulfaGENIX | , | Website gone, Jan 2019 |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Medistem | , | Bought by Intrexon Dec 2013 |
| Facet Biotech | , | Bought by Abbott 2010 |
| K2M | , | Acquired by Stryker, Nov 2018 |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| Maxivax | , | Renamed Release Therapeutics |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Microsize | Quakertown, PA | Microionization CDMO |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Madeira Therapeutics | , | Gone. No info |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| Takara Bio USA | San Jose, CA | Lab products |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| , | Acquired by Bausch + Lomb, Mar 2026 | |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| INEX Pharmaceuticals | , | Gone May 2007? |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| Chrysalis | Burlington, MA | GMP Space |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| icometrix | Boston, MA | Imaging AI |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| BrainScope | Bethesda, MD | EEG characterization |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Figure8 Surgical | , | Surrendered business in CA |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| CEL-SCI | Vienna, VA | Biologics |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Brilliant Research | , | Website gone Dec 2018 |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| Endothelix | , | Now owned by American Heart technologies |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Mitokine Bioscience | , | Seems to be a research library now |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Central Pharma | Bedford, UK | Filling, Packaging |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| TCXpress | , | Renamed BlueSphere Bio |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Kvvit Pharmaceutical | , | |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Abnovo | , | Gone |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| , | Website down Aug 2025 - Jan 2026 | |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Synergen | , | Bought by Amgen 1994 |
| Upstate Biotechnology | , | Closed 2005 |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Allenex | , | Bought by CareDx, Apri 2016 |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Syntagon | , | Acquired by Ardena, May 2018 |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Java Clinical | , | Website gone Jun 2019 |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| ProUroCare Medical | , | Gone |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Fusion Biopharma | , | Presumed gone |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Biobase | , | Bought by Qiagen, May 2014 |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Gensignia | , | Website Gone, Aug 2017 |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| , | No news 2019 - Sep 2025 | |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Ecopharm | , | Website down Feb 2021 |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| ZipBio | Seattle, WA | Compact Proteins |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| Roche | Penzberg, Germany | Diagnostics |
| Altiris Therapeutics | , | Presumed Gone |
| Aves Labs | , | Now part of Antibodies Inc |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| Entelos | , | Bankrupt |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| NextImmune | , | Renamed NXI Therapeutics |
| Cellf BIO | , | Website taken over Jan 2019 |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Satya | Hyderabad, India | Small Molecule |
| C/M/C Biologics | , | Now CMC Biologics |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| RNA Therapeutics | , | No website Mar 2020 |
| superDimension | , | Acquired by Covidien May 2012 |
| AstraZeneca | Baar, Switzerland | Biologics |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| AFID Therapeutics | , | Gone 2012 |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Precise Bio | , | Gone 2023 |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Oncofactor | , | Gone 2016 |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| GT Molecular | Fort Collins, CO | PCR Kits |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Genaera | , | Dissolved |
| , | Website taken over Feb 2026 | |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Peptimmune | , | Liquidated 2011 |
| Allotera Therapeutics | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Zensun | , | Website gone Jan 2019, Chinese company |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Antios Therapeutics | , | Shut down Feb 2023 |
| NeuClone | Sydney, Australia | Biosimilars |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Assay Designs | , | Now Enzo Life Sciences |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| ions.bio | Planegg, Germany | Biomarkers |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| VasoNova | , | Acquired by Teleflex Medical |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Prime Biologics | , | Seems gone 2019 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| PolyMedix | , | Bankrupt Apr 2013 |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| Groton Biosystems | , | Gone before Jun 2015 |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| Uncover Therapeutics | , | |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Anchen | , | Bought by Par Pharmaceutical |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Jaleva Pharmaceuticals | , | Gone |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Phasiq | , | Website gone Jul 2018 |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| BioMendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| Biotix | San Diego, CA | Lab Consumables |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Axbio | Santa Clara, CA | Biochips |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| CatSci | Cardiff, UK | Contract Research |
| AtheroGenics | , | Assets Sold Off 2009 |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Formex | , | Merged into BioDuro, Nov 2015 |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| Epigene Labs | Paris, France | Data Integration Platform |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| Obenomics | , | No website Apr 2014 |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Afaxys | Charleston, SC | Women's Health |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Aeres Biomedical | , | Gone Jul 2013 |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Splice Histology | Worcester, MA | Histopathology Services |
| Abnovel | , | Gone Jul 2010 |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Therix Medical | , | Seems gone |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Ho’ola Therapeutics | , | |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Kesios Therapeutics | , | Closed down according to investors |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| Mentrik Biotech | , | Gone |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Skylit Medical | , | Renamed Clarify medical |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Cerimon | , | Gone |
| , | No news 2017 - Apr 2026 | |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| Heraeus Medical | Changshu, China | Medical Devices |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Apollo Spine | , | Renamed G6 Spine |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| EyeTel Imaging | , | Gone Jul 2015 |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| Axplora | Pompey, France | CDMO Services |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| DynoSense | , | Shut down Sep 2022 |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| BionX Medical | , | Acquired by Ottobock |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Getinge | Delft, Netherlands | Medical Technology |
| BioDevek | , | Formerly LabCentral, seems gone |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Senseonics | Germantown, MD | Medical Devices |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| Formedix | , | Acquired by Certara, Oct 2023 |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| NeuMedics | , | Website taken over by massager sales |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Westat | Rockville, MD | Clinical trial design, management, services |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| numares | Houston, TX | Clinical Diagnostics |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| DxNow | , | Renamed ZyMot fertility |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Cue Health | , | Shut down May 2024 |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| , | Website down Dec 2025 - Apr 2026 | |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| , | Pivoted to crypto, Apr 2026 | |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| Syncro Medical | Langhorne, PA | Software development |
| Cymbiotics | , | Gone 2019-2020 |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| , | Website down Aug 2025 - Jan 2026 | |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| , | No news 2021 - Jun 2026 | |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Curadigm | , | folded into Nanobiotix |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Cogentis Therapeutics | , | No news 2017-2023 |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| Tryton Medical | , | Shut down Jan 2021 |
| icometrix | Leuven, Belgium | Imaging AI |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Harmony Labs | , | Now Ei |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| CrelioHealth | Columbia, MD | LIMS |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| Delta-Vir | , | Website down Mar 2023 |
| Ribocept | , | Defunct |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| , | Acquired by Millipore, Dec 2010 | |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Pique Therapeutics | , | Shut down Dec 2020 |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Beardsworth | , | Bought by TFS International 2013 |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| |
Cheshire, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| , | Renamed Cyclana Bio | |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| Venclose | , | Acquired by BD, Dec 2021 |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| , | No news 2017 - Apr 2026 | |
| EndoSphere | , | Gone pre-2011 |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| Concordia Healthcare | , | Now Concordia International |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| tiakis Biotech | Kiel, Germany | Biologics |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ResMed | San Diego, CA | Medical Devices |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| , | Website down Apr 2026, seems bankrupt | |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Stago | Marseille, France | Diagnostics |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| CertiRx | , | Shut down |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Avatar Biotechnologies | , | Gone 2010 |
| Corza Medical | Boulder, CO | Surgical Devices |
| Celregen | Hangzhou, China | iPSC |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Aspira Women's Health | Austin, TX | Diagnostics |
| NextPharma | London, UK | Contract Research & Development |
| Avam | Odessa, FL | Clinical Diagnostics |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| PharmaDerm | , | Part of Sandoz |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Cytiva | Freiburg, Germany | Medical Devices |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Pharmaron | Beijing, China | R&D Services |
| , | Acquired by Sebia, Sep 2024 | |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Ameridose | , | Shut Down 2012 |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Coldstream Laboratories | , | Bought by Piramal |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Quantamerix | , | No info since 2012, never registered in MA |
| , | Acquired by IMA Group, Oct 2025 | |
| Clear Image Technology | , | Now CIT Ortho |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Genovis | Cambridge, MA | Nanoparticles |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| , | Merged with Tecomet, Jan 2026 | |
| PregLem | , | Acquired by Richter, Oct 2010 |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| ProPharma Group | London, UK | Consulting |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| , | Website down Dec 2025 - Apr 2026 | |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| , | Website down Feb 2026 - Jul 2026 | |
| , | Website down, CEO gone Apr 2026 | |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Cytomatrix | , | Gone, Jun 2013 |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Develco Pharma | Schopfheim, Germany | Generics |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Glenveigh Medical | , | Website down Sep 2024 |
| Ossis | , | 3D-printed orthopedic implants |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| EndoInSight | , | Website taken over Sep 2021 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| , | Renamed Turing Medical | |
| MicroStem | , | Gone Jun 2017 |
| Summit Therapeutics | Dublin, Ireland | Utrophin modulation technology |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| , | Acquired by Repligen, Sep 2021, $150M | |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| Lavipharm | Peania Attica, Greece | Small molecules |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| AbbVie | Waco, TX | Contract Manufacturing |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| Vernacare | Blackwood, UK | Surgical Devices |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| , | Website down Dec 2025 - Apr 2026 | |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Javara | Wilmington, NC | Embedded Clinical Research |
| CyBio | , | Merged into Jena, Jul 2014 |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| , | Seems inactive Jan 2026 | |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| , | Website down Jan 2026 - Mar 2026 | |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| OxStem | , | Shut down 2021; Oxford spinout |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| PsiThera | Watertown, MA | Oral Small Molecules |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| Adepthera | , | Shut down 2014 |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| AMR Bio | Brighton, UK | Antimicrobials |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| , | Website down Jan 2026 - May 2026 | |
| Core Prognostex | , | Seems inactive |
| Kendle | , | Acquired by INC Research 2011 |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| , | No news 2019 - Sep 2025 | |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Website hijacked Oct 2025 | |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| Genomica | , | Shut down Sep 2022 |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| BiVACOR | Houston, TX | Heart replacement |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| Chrono Therapeutics | , | Shut Down 2019 |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| BioTheryX | San Diego, CA | Small Molecules |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| AliveDx | Eysins, Switzerland | Diagnostics |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Grifols | Clayton, NC | Biologics |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| , | Assets acquired by Alexion, Feb 2011 | |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| , | Website gone Feb 2026 | |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| , | Acquired by Altaris, Mar 2025 | |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Formation Bio | New York, NY | AI Drug Discovery |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| , | Renamed Helus Pharma, Jan 2026 | |
| CORONIS | Athens, Greece | Clinical Studies |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| , | Website down Aug 2025 - Jan 2026 | |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| Enesi Pharma | , | Renamed aVaxziPen |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Celerion | Lincoln, NE | Clinical Research |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Isolagen | , | Reorganized as Fibrocell Science |
| , | Website down Nov 2025 - Mar 2026 | |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| Celsense | , | Shut down Dec 2021 |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| FFE Therapeutics | , | Shut down Dec 2013 |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| StemPar Sciences | , | Website disappeared, no news |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| CoreBiome | , | Merged into Diversigen |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| , | Website down Dec 2025 - Jun 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| MediciNova | La Jolla, CA | Small Molecules |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Curry Pharmaceuticals | , | Closed 2008 |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| VaxNewMo | , | Renamed Omiose |
| MerciaPharma | , | No updates 2014-2023 |
| Meristem Therapeutics | , | Defunct |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| , | Renamed Grey Matters Health, Apr 2026 | |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| Acretia | , | Gone |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| BioTeam | Middleton, MA | Scientific IT consulting |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| , | Renamed Alethio Therapeutics | |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| LabConnect | Johnson City, TN | Lab Services |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Valneva | Lyon, France | Antibody Discovery |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| NIOX | Morrisville, NC | Asthma management device |
| RSSL | Wokingham, UK | Analytical Services |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Sirius Genomics | , | Gone |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| CeQur | Greenville, SC | Insulin pump |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| Genomas | , | Website gone May 2020 |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| EXO Biologics | Liège, Belgium | Exosomes |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| Ergomed | Frankfurt, Germany | Clinical Research |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| , | Website down Oct 2025 - Feb 2026 | |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| , | Stopped work Aug 2025, IP company | |
| , | No news 2019 - Oct 2025 | |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Tikcro Technologies | , | Liquidating 2021 |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| VersaPharm | , | |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| , | Pivoted to defense, Feb 2026 | |
| Opsonix | , | Shut down May 2018 |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| , | Website down Feb 2026 - Jul 2026 | |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Getinge | Solna, Sweden | Medical Technology |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Qool Therapeutics | , | Gone Jan 2021 |
| Sierra Surgical | , | Shut down Feb 2019 |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| NNS Clinical Research | , | Gone |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| |
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Hubot CDMO | South Bend, IN | Contract Filling |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| NeoVista | , | Gone 2011 |
| , | Website down Oct 2025 - Jan 2026 | |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Akesis LLC | , | Bankrupt 2015 |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| MLAB Biosciences | Needham, MA | Biologics |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Antigenics LLC | , | Now Agenus |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| , | Website down Dec 2025 - Apr 2026 | |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Animas | , | Shut down, Oct 2017 |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Linical | Stuart, FL | Clinical Research |
| XtalPi | Beijing, China | AI Drug Design |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| VG Life Sciences | , | Shell company |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| , | No news 2018 - May 2026 | |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Hypromatrix | , | Gone 2007 |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Taxolog | , | Website gone, Nov 2015 |
| , | Acquired by Insphero, Nov 2025 | |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| GL Technologies | San Diego, CA | Calibration Services |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| , | Website down May 2025 - Oct 2025 | |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Solace Pharmaceuticals | , | Out of business 2011 |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Avontec | , | Gone |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| EpitoGenesis | , | Gone 2017 |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| CombinatoRx | , | Now Zalicus |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Accera | , | Renamed Cerecin, Oct 2018 |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| Karykion | , | Website outdated, doesn't seem serious |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| Tecomet | Lansing, MI | Forging, CNC Machining, EDM, Finishing, Special Processes |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| Sundia | , | Part of BioDuro |
| Xtuit | , | Gone Jul 2018 |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| , | Website down Jan 2026 - May 2026 | |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| Sarstedt | Nümbrecht, Germany | Lab products |
| Arthus Biosystems | , | Shut down Oct 2015 |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| RoslinCT | Edinburgh, UK | Stem Cells |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| Sage Science | Beverly, MA | DNA Fractionation |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| , | Website down May 2025 - Jan 2026 | |
| Novotech | Bangalore, India | Clinical Research |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| , | Acquired by IQVIA | |
| Zai Lab | Cambridge, MA | Small Molecules |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Axplora | Shanghai, China | Purification Systems |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| , | Website down, Dec 2025 - Jun 2026 | |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Oak BioSciences | , | Shut down Nov 2024 |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| Pharmazz | Greater Noida , India | Small Molecules |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| , | Website down Dec 2025 - Apr 2026 | |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Novalar | , | Licensing agreement, essentially gone |
| Ximedica | Providence, RI | Medical Device Services |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Parion Sciences | Durham, NC | Mucosal Targets |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Biotel | , | Acquired by CardioNet, 2010 |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| DiagnoSearch | Thane, India | Clinical Research |
| Alerchek | , | Closed late 2016 |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| OncoQr | , | No news 2017 - Oct 2024 |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Sicor Biotech | , | Bought by Teva 2004 |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| , | Website down Aug 2025 - Jan 2026 | |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Noeledge | , | Shut down Jul 2024 |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| , | Website down Jan 2026 - May 2026 | |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| RFE Pharma | , | Gone 2019 |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| ImmuneXcite | , | Closed Oct 2017 |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Gensia Sicor | , | Renamed Sicor |
| Seeker Biologics | , | Shut down May 2023 |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| BBB Therapeutics | , | Bankrupt 2015 |
| , | Founder, Principal gone Sep 2024 | |
| Exelixis | Alameda, CA | Small Molecules |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Trophea Development | , | Liquidated Dec 2019 |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Nephrion | , | Closed 2006? |
| Zenosense | , | No website, shell company Nov 2020 |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| PreDxion Bio | , | Renamed Refractal |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Raytone Bio | , | |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| , | Website down Oct 2025 - Feb 2026 | |
| Norgine | Madrid, Spain | Specialty Pharma |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| DFE Pharma | Goch, Germany | Excipients |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| Securecell | Urdorf, Switzerland | Lab automation |
| AndroBioSys | , | Presumed gone |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| Tulyp Medical | , | Pressure-driven perfusion system |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| Cydan Development | , | Shut down Sep 2021 |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| GeneAssess | , | Gone |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Celerion | Vienna, Austria | Clinical Research |
| , | No news 2021 - Apr 2026 | |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Sysmex | Tokyo, Japan | Diagnostics |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Boston Scientific | Galway, Ireland | Medical Devices |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| Pharmaron | Cardiff, UK | R&D Services |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| , | Gone before Dec 2025 | |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Proacta | , | Gone 2014 |
| In Cell Art | , | Website taken over Feb 2025 |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| Verix Health | , | Renamed Serpex Medical |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Jina Pharmaceuticals | , | |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| Camurus | Lund, Sweden | Specialty medicines |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| , | No news 2020 - Apr 2026 | |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| KALA BIO | Arlington, MA | Drug Delivery |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| Getinge | Antalya, Turkey | Medical Technology |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Sepracor | , | Now Sunovion |
| Ventris Medical | Newport Beach, CA | Tissues |
| Proteologics | , | Apparently Gone |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| , | Website down Feb 2026 - Jul 2026 | |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Optovue | , | Renamed Visionix Sep 2021 |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| Viral Genetics | , | Now VG Life Sciences |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| , | Liquidated Jun 2025 | |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Novartis Animal Health | , | Acquired by Lilly |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Apobiologix | Toronto, ON | Biosimilars |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Cyllene Therapeutics | Paris, France | Pinpoint Gene Therapy |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| XDx | , | Changed name to CareDx |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Brain Vision | Morrisville, NC | EEG Systems |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Grifols | Durham, NC | Biologics |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| AccelaPure | , | Bankrupt 2007 |
| , | No news Jun 2021 - Jan 2026 | |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| Acelyrin | , | Merged into Alumis, May 2025 |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| sRNA Dx | , | aka sRNAlytics |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Medochemie | Limassol, Cyprus | Generics |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Perlegen | , | No Site |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| SemBioSys | , | Bankrupt, Jul 2012 |
| MOgene | St. Louis, MO | Genomic Services |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| Integer | Salem, VA | Medical & Surgical Devices |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| MiniVax | , | Gone Jan 2016 |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Actavalon | , | Shut down Dec 2020 |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| DDi | Basel, Switzerland | Clinical Software |
| , | Acquired by IQVIA | |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Cambrian Bio | New York, NY | Small Molecules |
| CTC | Uppsala, Sweden | Clinical Site Network |
| , | No news Sep 2010 - Oct 2025 | |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Getinge | Mumbai, India | Medical Technology |
| Compucyte | , | Sold Assets to Thor Labs |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Genomics | Oxford, UK | Human Genetics Platform |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| DiaGenic | , | Switched to energy sector |
| Vernay | Griffin, GA | Fluid Control Solutions |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| CorWave | Clichy, France | Blood Pumps |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| RION | Rochester, MN | Exosome Therapeutics |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| Prolexys Pharmaceuticals | , | Website Gone |
| bioTHER | , | Gone |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| NX Development | Lexington, KY | Brain Imaging |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Genetron Health | Beijing, China | Diagnostics |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| LyoTechnica | , | Gone |
| , | Website down Jan 2026 - May 2026 | |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| DC Biosciences | , | Shut down Jul 2023 |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Fabion Pharmaceuticals | , | Gone 2013? |
| InnoCare | Beijing, China | Cancer Treatments |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| , | ||
| Daré Bioscience | San Diego, CA | Women's Health |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Anoixis | Natick, MA | Pharmacometric Services |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Revvity | Boston, MA | Diagnostics, Services |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| , | Renamed Peritia, Jan 2026 | |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Ergomed | Prague, Czech Republic | Clinical Research |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| , | No news 2017 - Apr 2026 | |
| arGEN-X | , | Older name for Argenx |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Velomedix | , | Shut down 2014 |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| AQEMIA | Paris, France | AI Drug Discovery |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| Wetlin Research Associates | , | Centerwatch only |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| Orthologic | , | Now Capstone Therapeutics |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| Aviria Biosciences | , | Disappeared |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Tecomet | Wilmington, MA | EDM, FPI, Passivation, Ultrasonics, Forging |
| Mighty Therapeutics | Needham, MA | Mitochondrial disease therapies |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| CBH ClinTrials | , | now CenExelCBH |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Ergomed | London, UK | Clinical Research |
| Annova Chem | , | Gone, 2017 |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| Lupin | Mumbai, India | Generics |
| EuroAPI | Paris, France | API Production, CDMO |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Cell Technology | , | Acquired by ICT |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| Syndexa Pharm | , | Closed Jul 2013 |
| Purdue Pharma | Stamford, CT | Small Molecules |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| MitoStem | , | Seems gone |
| Trinity Drug Partners | , | Gone |
| Howfond | , | Website gone, Jul 2015 |
| Gastrotech | , | Now Rose Pharma |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Cardima | , | Bankrupt Dec 2010 |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Chiron | , | Bought by Novartis |
| Roxall | , | No news 2019 - May 2025 |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| InnoCare | Shanghai, China | Cancer Treatments |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| OD-OS | Teltow, Germany | Retinal Laser |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Zai Lab | South SF, CA | Small Molecules |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| Tecomet | Farmington Hills, MI | Bone In-Growth Coating, Bearing Surface Solutions |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Taligen Therapeutics | , | Acquired by Alexion |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Scinomix | Earth City, MO | Lab Automation Products |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Excelsyn | , | Bought by AMRI |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Valsphere | , | Website gone Nov 2019 |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Adheren | , | Gone, 2016 |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| Commave Therapeutics | , | |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| Medrobiotics | , | Bankrupt, May 2024 |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| ChunLab | , | Renamed CJ Bioscience |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Bionsight | Chuncheon, Korea | Database For Research |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Labopharm | , | Bought by Paladin 2011 |
| Sophiris Bio | , | Shut down May 2020 |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| iBridge Medical | , | Website gone Jan 2020 |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| GSL Biotech | , | Acquired by Dotmatics |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| Cognis Corp | , | Acquired by BASF 2010 |
| Atherotech | , | Shut down Feb 2016 |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Cardeas Pharma | , | Gone, 2017 |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| Stealth Therapeutics | , | Gone |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| Empatica | Milan, Italy | Seizure Detection |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| , | Website down Aug 2025 - Jan 2026 | |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| , | Main person has four other jobs, Dec 2025 | |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| RecomGenex | , | Renamed TargetEx Biosciences |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| Gennova Bio | Pune, India | mRNA vaccine |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| , | Liquidating, Mar 2025 | |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Avatar Medical | Paris, France | Surgical Visualization |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Abcam | Waltham, MA | Antibodies |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| UVision 360 | , | Renamed Luminelle |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Apieron | , | Shut down, May 2010 |
| Altasciences | Overland Park, KS | Contract Research |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Piramal | Sellersville, PA | CDMO |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| Owkin | New York, NY | AI for Medical Research |
| Medrio | San Francisco, CA | Clinical Trial Software |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Calixar | Lyon, France | Membrane Proteins |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| CardiRen Biomedical | , | Gone Aug 2017 |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| VB Spine | Allendale, NJ | Spinal Implants |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| , | Website down Feb 2026 - Jul 2026 | |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| Zai Lab | Beijing, China | Small Molecules |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| , | Website down Sep 2025 - Dec 2025 | |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| |
Göttingen, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| , | Shell used for reverse merger by Serapha Bio, Jun 2026 | |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| NeoPharm | , | Merged with Insys Therapeutics |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| EPISONA | , | Gone Nov 2018 |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| Atlas Genetics | , | Renamed Binx Health |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| , | Acquired by Syner-G BioPharma Group | |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| Iquity Labs | , | Merged into Decode Health |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Starkey | Eden Prairie, MN | Hearing Aids |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| LightMed | , | |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| Biocoat | Horsham, PA | Medical Device Coatings |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| BioMAS | , | Ceased operating, Jul 2016 |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| MedCision | , | Assets bought by MedCision, May 2018 |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Proscia | , | |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| , | Website down Jun 2025 - Dec 2025 | |
| Mytos | London, UK | Automated Cell Culture |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| CureGene | Shanghai, China | |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| Sequel Pharmaceuticals | , | Gone |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| HeartVista | , | Renamed Vista.ai |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Lumen Bioscience | Seattle, WA | Biologics |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| Genopis | , | Acquired by Wacker Feb 2021 |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Concerto HealthAI | , | Renamed ConcertAI |
| Lupin | Baltimore, MD | Generics |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Altasciences | Cypress, CA | Contract Research |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| VitaCyte | Indianapolis, IN | Collagenase |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Proveri | , | Gone 2016 |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Orochem | Naperville, IL | Reagents, Automation |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| , | Website down Oct 2025 - Feb 2026 | |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Hygtia Therapeutics | , | |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| , | Website down Jun 2025 - Dec 2025 | |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Lean Biologix | Norfolk, MA | Consulting |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| Kurin | San Diego, CA | Blood Collection Technology |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| Pharmos | , | Gone |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| Altasciences | Harleysville, PA | Contract Research |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Jetequip | Boucherville, QC | Fluid Handling |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| EVA Pharma | Giza, Egypt | Branded Generics |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Iktos | Paris, France | AI for New Drug Design |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| BioTransplant Inc | , | Bankrupt, 2003 |
| GnuBIO | , | Bought by Bio-rad |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Bayer | Mexico City, Mexico | Small Molecules |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| Bionovica | , | Website gone Dec 2022 |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Alfama | , | Merged into Proterris, May 2017 |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| Omnimmune | , | Shell company, trademark abandoned |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Scion NeuroStim | , | Presumed gone |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| MabSpace Biosciences | , | Renamed Transcenta |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Cytokinetics | South SF, CA | Small Molecules |
| Echo | San Diego, CA | Microscopy |
| Lombard Medical | Didcot, UK | Medical Devices |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Covenant Therapeutics | , | Gone |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| Cristers | Suresnes, France | Generics |
| Biogenes | Berlin, Germany | Antibodies |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Parsolex | , | |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Dalex Biotech | , | Gone |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Synthace | London, UK | Development Software |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Sania Therapeutics | London, UK | CNS Treatments |
| NanoSort | , | Renamed NanoCellect |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| QuA Vodis | , | Gone |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| HawkCell | Lyon, France | MRI Research Technology |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| PepLib Biotech | Metuchen, NJ | Peptides |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| Streck | La Vista, NE | QC & Diagnostic Products |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Wepredic | Saint Gregorie, France | Cell Lines |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| Active Pass Pharmaceuticals | , | Gone |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Diamed | , | Bought by Bio-rad |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| Piramal | Grangemouth, UK | CDMO |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Polytherapeutics | , | Gone Jun 2018 |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| ObvioHealth | New York, NY | Clinical Study Software |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Primevera Therapeutics | , | |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Alfasigma | Bologna, Italy | Small Molecules? |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| , | Website down Oct 2025 - Feb 2026 | |
| Procognia | , | Website Gone, Layoffs 2014 |
| Scios | , | Bought by JnJ, Feb 2003 |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| Amstem | , | SEC problems |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| Virometix | Schlieren, Switzerland | Vaccines |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Genoma | , | Website gone May 2021 |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| Abbott | Mississauga, ON | Diagnostics |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Nexus BioPharma | , | No news 2017-2022 |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Caidya | Shanghai, China | Clinical Research Organization |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics, CDMO |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| iCareDx | , | Renamed AcuamarkDx |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Weatherwax | , | Renamed General Proximity |
| AstraZeneca | New Haven, CT | Biologics |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| Plus Therapeutics | Charlottesville, VA | Radiotherapy |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| Alchemia | , | Gone, late 2017 |
| Zyomyx | , | Closed as of 2014 |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Medtronic | Cincinnati, OH | Medical Devices |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Alimentiv | San Diego, CA | Clinical Services |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Pharos iBT | , | aka Pharos iBio |
| Antyra | , | Gone |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| Scholar Rock | Cambridge, MA | Biologics |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| Doloromics | , | Shut down Mar 2025 |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Ablacon | , | Shut down Mar 2024 |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| CLCbio | , | Acquired by Qiagen, 2013 |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Altus Biologics | , | Vertex Subsidiary |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments, CMO |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| Rhythm Health | , | Renamed Motus Therapeutics |
| Molecular Detection Inc | , | Gone 2016 |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| ADS Biotechnology | , | Bankrupt 2014 |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Delpharm | Tours , France | Contract Manufacturing |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Lab Owl | , | Part of Inflexion Point |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Vie Diagnostics | , | Renamed Phoresa |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Bio-Processing Alliance | , | Website now for a training company |
| Protein Metrics | Boston, MA | Protein characterization software |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| CMC Biologics | , | Now part of AGC Biologics |
| Matritech | , | Assets bought by Matritech 2007 |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Bracco | Plainsboro, NJ | Imaging |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| Proxima | New York, NY | AI Protein Folding Platform |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| Acologix | , | Closed Aug 2011 |
| Blu Biotech | , | Website down May 2023, CEO gone |
| BioAMPS | , | Gone |
| West-Ward | , | Now part of Hikma |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Accellacare | Wilmington, NC | Clinical Research |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| Lung LLC | , | Renamed Lung Biotechnology |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Roche | Basel, Switzerland | Small Molecules |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| SK Biotek | , | part of SK pharmteco |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| AMDL | , | Now Radient Pharmaceuticals |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Celixir | , | Shell acquired Dec 2023 |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| Kura Oncology | San Diego, CA | Small Molecules |
| Macusight | , | Effectively acquired by Santen, 2008 |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| Regulome | , | Gone 2006 |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| EpiFinder | , | Gone May 2025 |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| BioSpherex | , | Renamed Metabiomics |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Resilience | East Norriton, PA | Biomanufacturing |
| Lectus Therapeutics | , | Sold off product |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Flux Biosciences | , | Shut down, ~2022 |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Abbott | Alameda, CA | Diabetes Care |
| , | Website down Sep 2025 - Feb 2026 | |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| DP Clinical | Rockville, MD | Clinical Research |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| , | Website down Nov 2025 - Apr 2026 | |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Viatris (2) | Hyderabad, India | Small Molecules |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| AlloThera | , | Gone, 2018 |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| PhotoThera | , | Ceased operations Dec 2012 |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| M3 Wake Research | Encino, CA | Clinical Research |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Alxerion Biotech | , | Gone May 2021 |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| , | No news Aug 2019 - Jan 2026 | |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| EMKinetics | , | Seems inactive Feb 2021 |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| , | Renamed NeuraNova, Jan 2026 | |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| Bioventus | Cordova, TN | Orthobiologics |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Sentien Biotechnologies | , | Shut down late 2021 |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| MaxThera | , | Shut Down Dec 2011 |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Pharmascience | Montréal, QC | Generics |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Avax Technologies | , | Gone |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| , | Website down Jun 2025 - Dec 2025 | |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| SR Pharma | , | Now Silence Therapeutics |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| NemaPharm | , | Defunct? |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| Piramal | Mumbai, India | CDMO |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| , | Website down Jul 2025 - Dec 2025 | |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| , | Website down Jan 2026 - May 2026 | |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Xenomics | , | Now TrovaGene |
| Panaxia | Lod, Israel | Medical Cannabis |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Piramal | Morpeth, UK | CDMO |
| Zephyr AI | McLean, VA | AI Data Analysis |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| , | Liquidating Jan 2026 | |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| Summit Therapeutics | Princeton, NJ | Utrophin modulation technology |
| , | Website taken over Mar 2026 - Apr 2026 | |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| BGI | Kobe, Japan | Genetic Testing |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Silence Therapeutics | London, UK | RNAi |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| OverT Bio | New York, NY | Cell Therapy |
| Entropia Biosciences | , | Shut Down June 2019 |
| AbGenomics | , | Renamed Altrubio |
| Cognosetta | , | Gone 2021 |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| , | No news 2021 - Sep 2025 | |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| , | Winding down, Dec 2025 | |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| , | Website down Jan 2026 - May 2026 | |
| On-Q-Ity | , | Closed 2013 |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation pseudo-subsidiary | |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| Spear Bio | Woburn, MA | Immunoassays |
| EyeCyte | , | Gone 2014 |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| XaTek | , | No news 2021 - Feb 2025 |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Transnetyx | Cordova, TN | Automated PCR Services |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| Phenoquest | , | Website gone, Oct 2015 |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Saffron Therapeutics | , | Website down Oct 2021 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| Pharmaron | Hertfordshire , UK | R&D Services |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| Digene | , | Merged with Qiagen |
| , | Acquired by Altivera Medical, Mar 2026 | |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| , | Shut down Jan 2026 | |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Personalis | Fremont, CA | Genome Services |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Opentrons | New York, NY | Lab Automation Robots |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| , | Website taken over, Jan 2026 | |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| GEROPHARM | Moscow, Russia | Large drug maker |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Proteins and Peptide Management | , | Now Adocia |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| Stelvio Oncology | , | Gone late 2019 |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Amaranth Medical | , | Website gone, Apr 2019 |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| Apotech Consulting | London, UK | Life Science Consulting |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| GeneProt | , | Shut down Apr 2005 |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| Flownamics | Madison, WI | Automated Sampling |
| Moximed | Fremont, CA | Joint treatment |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| Obecure | , | Inactive, no info |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Arxspan | , | Renamed SciY |
| Steris | Mentor, OH | Contamination Control |
| MYcroarray | , | Renamed Arbor Biosciences |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| Savant HWP | , | Gone 2019 |
| , | Acquired by Chiesi, Apr 2023 | |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| , | Shut down Jul 2025 | |
| , | Acquired by InformedDNA, Mar 2025 | |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Viragen | , | Liquidated Oct 2007 |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Clinilabs | Eatontown, NJ | Clinical Research |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| Evidera | , | Acquired by PPD, 2016 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Exalta | Bethlehem, PA | Orthopedic Devices |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| OraSure | Bethlehem, PA | Diagnostics |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| Inflammix | , | Renamed AnchorBio Solutions |
| Snorx | , | Renamed Zelegent, May 2015 |
| ProteoVec | , | Website gone Jul 2015 |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Ovation.io | Portland, ME | LIMS |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| Gen-probe | , | Acquired by Hologic 2012 |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| AnaBioTec | , | Now Anacura |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| , | Assets being sold off May 2026 | |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Xeris Biopharma | Chicago, IL | Injectables |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Nucleus Network | Herston, Australia | Clinical Research |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Qualiber | , | Presumed inactive, website gone |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Omnia Biologics | , | Website gone Sep 2017 |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| , | Selling pipeline, winding down Jul 2025 | |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Bacthera | , | Liquidating, Feb 2025 |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Alumis | South SF, CA | Autoimmune Treatments |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Enzo Biochem | , | |
| Aresus Pharma | , | Seems folded in to Dermago |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| ProSci | Poway, CA | Antibodies, etc. |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| OBDURO Biotechnologies | , | never a registered CA business |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| Lexogen | Vienna, Austria | RNA kits |
| Global BioDevelopment | , | Website gone |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| Neocis | Miami, FL | Dental Surgery Robots |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Boehringer Ingelheim | Vienna, Austria | Small Molecules, Biologics, CDMO |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Selten Pharma | , | Gone 2017 |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| TNI Biotech | , | Renamed Immune Therapeutics |
| , | No news 2019 - Jan 2026 | |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| Tecomet | Wilmington, MA | EDM, Ultrasonics, Electrical Beam Welding, Vacuum Brazing |
| Compliment Corporation | , | Closed Dec 2011 |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Frenova | Waltham, MA | Renal clinical research |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Invibio | Cleveleys, UK | Implants |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Unilife | , | Bankrupt, Apr 2017 |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| Tecomet | Cork, Ireland | CNC Machining, Finishing, Inspection, Plastics Machining, Shotpeening |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| , | Shut down Oct 2025 | |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Kerecis | Arlington, VA | Wound Healing |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| ISM Therapeutics | , | Website Gone, no response from employees |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Vyteris | , | Bankrupt 2012 |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Celerion | Zurich, Switzerland | Clinical Research |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| JCL Bioassay | , | Renamed CMIC |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| American Stem Cell | , | Changed name to Targazyme |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| CO.DON | Leipzig, Germany | Cell Therapies |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| XtalPi | Cambridge, MA | AI Drug Design |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Admescope | Oulu, Finland | ADME-tox services |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| Predictive Biosciences | , | Closed 2013 |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| , | ||
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ergomed | Surrey, UK | Clinical Research |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Mott | Farmington, CT | HPLC system components, Filtration |
| , | Filings late Jan 2026; No website May 2023 - Mar 2026 | |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| Elucid | Boston, MA | Arterial Analysis Software |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| RegeneraTEch | , | Renamed Regencor |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| , | Website down Jan 2026 - May 2026 | |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| GCP ClinPlus | Beijing, China | Clinical Research |
| KynderMed | , | Renamed Prena |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| , | Acquired by Generic Specialties, May 2016 | |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| TauTaTis | , | Shut down 2011 |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| Semaphore Solutions | Victoria, BC | Lab Software |
| Audubon Bioscience | Houston, TX | Biospecimens |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Novonesis | Bangalore, India | Enzymes |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Nuredis | , | Shut Down Apr 2021 |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Cytiva | Tokyo, Japan | Medical Devices |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Pharsight | , | Merged with Tripos to become Certara |
| , | Acquired by Kite, Aug 2025 | |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| , | Website taken over Mar 2026 | |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Pristine Bioproduction | , | Not a going concern |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| AJES Life Sciences | , | Renamed L2P Research |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Sharp | Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| METiS Technologies | , | |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| Elix | Tokyo, Japan | AI Drug Discovery |
| , | Renamed Kyntra Bio, Jan 2026 | |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| Idience | Seoul, Korea | Cancer Therapies |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| |
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Piramal | Turbhe, India | CDMO |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| CoaguSense | Fremont, CA | Coagulation monitor |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Enterey | Irvine, CA | Life Science Consulting |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| Azopharma | , | Bankrupt, Apr 2010 |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| Sure Genomics | , | Gone 2014? |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Abselion | Cambridge, MA | Biologics Quantification |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| Avance Clinical | Firle, Australia | Clinical Research |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| Aerogen | Galway, Ireland | Nebulizers |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| Revance | Nashville, TN | Movement Disorder Treatment |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| ProPharma Group | Deerfield, IL | Consulting |
| , | Website down May 2025 - Dec 2025 | |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Piramal | Mahad, India | CDMO |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| Yicura | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| American Regent | Shirley, NY | Generics |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Accellacare | Bristol, TN | Clinical Research |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| Calico | South SF, CA | Aging treatments |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Cure Foreward | , | Services suspended, May 2017 |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Roche | Pleasanton, CA | Diagnostics |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Onorach | Dundee, UK | Clinical Trial Management |
| Sancilio | , | Now Micelle BioPharma |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| |
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Axsome Therapeutics | New York, NY | CNS treatments |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Cellcion | , | Website gone, company going inactive |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Applied Molecular Genetics | , | Renamed Amgen |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| BG medicine | , | Gone 2019 |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| , | Renamed AtaiBeckley | |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Action Pharma | , | Abbott acquired product, 2012 |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| AAVLife | , | Renamed Annapurna |
| Biophytis | Paris, France | Therapies for aging diseases |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Corcym | London, UK | Implants, Instruments |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Epana Bio | Berkeley, CA | Autoimmune Treatments |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| EsbaTech | , | Bought by Alcan |
| , | Crypto Pivot, Nov 2025 | |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| Sensys Medical | , | Old company, no website, presumed defunct |
| , | Website down Feb 2026 - Jul 2026; Virtual, US/Hong Kong | |
| Devsynthesis | Austin, TX | Chemistry CRO |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| , | Website down Jan 2026 - May 2026 | |
| Abbott | Irving, TX | Devices |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Advangen | , | Acquired by Cellmid, May 2013 |
| , | Acquired by Viatris, Oct 2025 | |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| , | Part of ICE Pharma | |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Wacker | Jena, Germany | Biologics CDMO |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Evalve | , | Owned by Abbot Vascular |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Ceronco Biosciences | , | Gone 2015? |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| Alt Bioscience | , | Now PDx Biotech |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| , | Renamed Virchow | |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| SIRGA Advanced Biopharma | , | Appears defunct |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| REPROMEDIX | , | Gone 2012 |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Curadev | Kent, UK | Immuno-oncology |
| PreventAGE Health Care | , | fka Journey Biosciences |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Meissner | Castlebar, Ireland | Lab Systems |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| Intact Genomics | St. Louis, MO | PCR kits |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| Pharming Group | Leiden, Netherlands | Biologics |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Trimeris | , | Merged with Synageva |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Almac | Souderton, PA | Pharmaceutical Services |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| SpinalMotion | , | Website gone, 11-30-14 |
| , | Acquired by Glaukos, Aug 2025 | |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| PRA International | , | Now PRA Health Sciences |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Launchpad Therapeutics | , | |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| MiNA Therapeutics | London, UK | Small activating RNA |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Rgene | , | Late business filings Aug 2021 |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Madera Biosciences | , | Shut down Aug 2020 |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| Agrisera | Vännäs, Sweden | Antibodies |
| ArunA Biomedical | , | |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| RS Medical | Vancouver, WA | Medical Devices |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Exodon | , | Website taken over, Jul 2014 |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Nigra | , | Acquired by Vernalis |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Syneos Health | Princeton, NJ | Clinical Development |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Elan | , | Bought by Perrigo, Dec 2013 |
| Originus | , | Gone |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| , | Website down Jun 2025 - Dec 2025 | |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| NeuroVista | , | Website Gone, President has new job |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| EMD Serono | Boston, MA | Biologics |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| , | Website down May 2025 - Dec 2025 | |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| Salus Bioscience | , | Forfeited in CA |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| LFB | Paris, France | Plasma derived drug products |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| Accellacare | Cary, NC | Clinical Research |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| , | Website down Jun 2025 - Dec 2025 | |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Cirina | , | Merged with Grail, May 2017 |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| , | Now PiSA USA | |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| Dexcom | San Diego, CA | Glucose Monitors |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| KVK Tech | Newtown, PA | Generics |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| , | No news 2022 - Mar 2026 | |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| Veracyte | South SF, CA | Cytology Diagnostics |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| AlphaMab Oncology | Suzhou, China | Biologics |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| Oxitope | , | Shut Down Feb 2019 |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Compugen | San Francisco, CA | Biologics |
| Metrohm | Houston, TX | Lab Data Management Software |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| MSD | Carlow, Ireland | Vaccines |
| , | Bankruptcy, Jun 2026 | |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Criterium | Saratoga Springs, NY | Clinical Research |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| Athlon Pharma | , | No news since 2006 lawsuit |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| , | Website down Oct 2025 - Feb 2026 | |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| BZL Biologics | , | Gone 2003 |
| , | No news 2020 - Dec 2025 | |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| , | Website down Oct 2025 - Feb 2026 | |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| SOCIUM | Tokyo, Japan | Contract Research |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| DNAtrix | , | Gone late 2023 |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| AtCor Medical | , | Now part of CardieX |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| , | Website down Feb 2026 - Jul 2026 | |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| GlioCart | , | |
| Nucryst | , | Bought by Smith & Nephew |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Nephros | South Orange, NJ | Dialysis Devices |
| Lavipharm | East Windsor, NJ | Small molecules |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| ImmunArray | , | Shut Down, 2021 |
| AlphaVax | , | No employees on LI. Not sure active |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| Piramal | Lexington, KY | CDMO |
| SoftGenetics | State College, PA | Software for genetic analysis |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| SDIX | Newark, DE | Diagnostics |
| GenomeKey | Bristol, UK | IVD Device |
| , | Website down Dec 2025 - Apr 2026 | |
| Diatos | , | No website, founded 1999 |
| Proteome Sciences | Surrey, UK | Proteomics |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| , | Website redirecting to Tedan Surgical Systems, Jul 2026 | |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Molecular Loop | Woburn, MA | NGS Technology |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| RadioRx | , | Now EpicentRx |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| DDi | Singapore, Singapore | Clinical Software |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| ApoVax | , | Shut down Jul 2014 |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Whole Biome | , | Renamed Pendulum Biosciences |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Renamed Precursion Biosciences, Jun 2026 | |
| SironRx | , | Website gone Jul 2015 |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Pharmaron | Beijing, China | R&D Services |
| ArKal Medical | , | Gone 2012 |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| SutroVax | , | Renamed VaxCyte |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| DLK Medical Technologies | Dallas, TX | OTC |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| IQVIA | Parsippany, NJ | Clinical Research |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Kailo Pharma | , | |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| InxMed | Beijing, China | Oncology Treatments |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Duramed | , | Acquired by Barr Labs 2001 |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| , | ||
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Supeira | , | Website gone Mar 2023 |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| ABgene | , | Bought by Apogent, Dec 2001 |
| Silere Medical Technology | , | Shut down Dec 2013 |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Turku Bioscience | Turku, Finland | Research Services |
| Ezose Sciences | , | Rebranded as S-bio |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Calmune | , | Liquidated |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Plus Therapeutics | Houston, TX | Radiotherapy |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| Berlex | , | Now Bayer |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| South Coast Clinical Trials | , | |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Organix | Woburn, MA | Contract Research & Development |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| |
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| QSV Biologics | , | Website Gone |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Coating Place | Verona, WI | Drug Delivery Services |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Trine Pharmaceuticals | , | Closed 2008 |
| GlySens | , | Bankrupt Nov 2022 |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| iTherapeutics | , | Doubt they do anything |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Altasciences | Auxvasse, MO | Contract Research |
| Techne | , | Part of R&D Systems |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Novaliq | Cambridge, MA | Drug Delivery |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| , | Renamed Racura Oncology, Dec 2025 | |
| Ximedica | San Francisco, CA | Medical Device Services |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| Theranos | , | Dissolving, Sep 2018 |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| , | Website gone Jan 2026 - Jul 2026; aka Weimou Biotechnologies? | |
| DIAsource Diagnostics | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Advancells | Noida, India | Stem Cell Treatments |
| EDAP Technomed | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Advaned Viral Research | , | Shut down 2009 |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| Indena | Milan, Italy | CDMO |
| DiAthegen | , | Website Gone Oct 2015 |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Curadev | Noida, India | Immuno-oncology |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| , | Acquired by Azenta, Feb 2023 | |
| PluroGen Therapeutics | , | Gone 2013 |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| Avistone | Beijing, China | Precision Oncology |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Xylo | Boulder, CO | Psychedelics |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| Gilson | Middleton, WI | Lab Supplies |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| , | Website down Jun 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Pevion Biotech | , | Gone, 2-19-14 |
| Bonenta | , | Website gone |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Vascular Genesis | , | Website gone Aug 2022 |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| , | Website down Jun 2025 - Dec 2025 | |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| Avalyn Pharmaceuticals | Boston, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Hemay Pharmaceutical | Tianjin, China | |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| , | Website gone Feb 2026 - Apr 2026 | |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Acumed | Hillsboro, OR | Medical Implants |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Theramex | London, UK | Women's Health |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Bioclinica | , | Merged with ERT, 2021 |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Cellenion | Berlin, Germany | Single Cell Testing |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments, ADCs |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Metis Laboratories | , | |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| Metrochem | Hyderabad , India | APIs |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| Rox Medical | , | Gone 2019 |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| , | Shut down Jul 2025 | |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| Nura | , | Acquired by Omeros |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| ReactDx | Melbourne, FL | Wireless Monitors |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| Scintillant Bioscience | , | Gone May 2025 |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Tequesta BioScience | , | Defunct |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Getinge | Feldkirchen, Germany | Medical Technology |
| , | Website down Dec 2025 - Apr 2026 | |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| R2M Pharma | South SF, CA | Drug Development Services |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| Stago | Franconville, France | Diagnostics |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| Vectura | , | |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Abpro | Lexington, MA | Antibodies |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Intelliseq | Kraków, Poland | Genome Informatics |
| SL Pharma Labs | , | Website gone May 2018 |
| Kuano | Cambridge, UK | AI Drug Discovery |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| LexaMed | Toledo, OH | Life Science Consulting |
| , | Website down Feb 2026 - Jul 2026 | |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Nanogen | , | Now Epoch Biosciences |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Menarini | Firenze, Italy | Small Molecules |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Partek | , | Acquired by Illumina, May 2024 |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| , | Bankruptcy Oct 2024 | |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Genomic Solutions | , | Acquired by Digilab |
| Axikin Pharmaceuticals | , | Closed per Google |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| Roche | Mannheim, Germany | Diagnostics |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| , | Website down Nov 2025 - Apr 2026 | |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Rafagen | , | Website redirecting to Rophibio |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| AB ANALITICA | Padua, Italy | Sequencing products |
| Anaheim Clinical Trials | , | Now CenExelACT |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| OXON | Madrid, Spain | Real World Evidence |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| Xcelthera | , | Shut down, Apr 2021 |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| , | Crypto Pivot, Oct 2025 | |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Velos | , | Acquired by WCG, Mar 2018 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Celerion | Belfast, UK | Clinical Research |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| VIVUS | Campbell, CA | Small Molecules |
| Pharmaron | Tianjin, China | R&D Services |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| ARC Medical | , | Acquired by Typenex Medical |
| , | Website down Jan 2026 - May 2026 | |
| Avivo BioOptics | , | Website down Dec 2022 |
| Gene Logic | , | Bankrupt |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| US Labs | , | Bought by Labcorp |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Alkermes | Dublin, Ireland | Small Molecules |
| Berg | , | Acquired, Jan 2023 |
| Stellartech Research | Milpitas, CA | Electronic device development |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Stago | Tianjin, China | Diagnostics |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| , | Acquired by Sebia, Dec 2022 | |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| |
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| CROSSJECT | Dijon, France | Needle-free Injection |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| , | Website down Feb 2026 - Jul 2026 | |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| Claritas Genomics | , | Closed Jan 2018 |
| Eos Biosciences | , | Shut down Oct 2020 |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Extract Technology | Mauston, WI | Containment Equipment |
| DiaVax Biosciences | , | Renamed Helocyte |
| CovX Research | , | Bought by Pfizer |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Resilience | Hamilton, OH | Biomanufacturing |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| Chrysalis | Morrisville, NC | GMP Space |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| , | Acquired by IQVIA | |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| Ingenetix | Wien, Austria | PCR Products |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| , | Acquired by BioIVT, Aug 2024 | |
| , | Subsumed into GSK, Jun 2026 | |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Surepharm | , | Liquidating, Apr 2025 |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Sorbent Therapeutics | , | Gone post 2014 |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| American Biooptics | , | Renamed Avivo BioOptics |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| Adlyfe | , | Gone, no info |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Getinge | Plewiska, Poland | Medical Technology |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| Zyagen | San Diego, CA | Life Science Reagents |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Inno Biologics | , | Website gone Jun 2020 |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Alliances Catalyst | , | Liquidated |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| preclinics | Potsdam, Germany | Contract Research |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Regenerative Sciences | , | Took on Regenexx product name |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| Envisagenics | New York, NY | Software-based drug discovery |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Akceli | , | Shut down, Sep 2004 |
| , | No news 2020 - Apr 2026 | |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Akela Pharma | , | Now PharmaForm |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Tides Medical | Lafayette, LA | Biologics |
| Tgen Tech | , | Renamed Annoviant |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Photonion | Schwerin, Germany | Analytical Equipment |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| Insulete | , | Website gone, presumed inactive |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Cellevolve Bio | , | Shut down Aug 2023 |
| , | Acquired by Hologic, Jan 2025, $350M | |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| Isis Biopolymer | , | Website taken over |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| , | Acquired by Paradigm Health, Jan 2023 | |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| Ciphergen | , | Now Vermillion |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| Esoterix | , | Bought by LabCorp, May 2005 |
| , | Dissolved Jun 2019 | |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Epic Pharma | Laurelton, NY | Generics |
| Purdue Pharma | Wilson, NC | Small Molecules |
| NewVac | , | |
| Advantagene | , | Renamed Candel Therapeutics |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Kirax | , | Website Gone |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Meta-Iq | , | Website gone Jun 2020 |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| CTG Pharma | , | Gone |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| , | ||
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Hikma | London, UK | Medication Delivery |
| , | Website taken over May 2026 | |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| AerovectRx | , | No news since 2006, Website gone |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Norganoid | Macclesfield, UK | Organoid Technology |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Refeyn | Oxford , UK | Mass Photometry |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| , | Website taken over Feb 2026 | |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| , | Renamed Algernon Health, Oct 2025 | |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Domainex | Essex, UK | Drug Discovery Services |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Telo Genomics | Toronto, ON | Diagnostics |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| Kulira Technologies | , | Website Gone Oct 2016 |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Molsoft | San Diego, CA | Drug Design Software |
| Abpro | Burlington, MA | Antibodies |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| Neoantigenics | , | Website gone Sep 2017 |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| PowderMed | , | Acquired by Pfizer 2006 |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| |
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Abbott | Singapore, Singapore | Diagnostics |
| Alaeras | , | Dissolved Jan 2014 |
| , | Website redirecting to Talon Group, Jul 2026 | |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Warnex | , | Merged into DIAGNOS Inc |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Oncodesign Services | Dijon, France | Preclinical services |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Medivector | , | Gone late 2018 |
| Texcell | Frederick, MD | Contract Research |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| , | Website down Jul 2026; Linkedin gone Jul 2026; Filings late Aug 2025; fka AilseVax | |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| , | Website down Jan 2026 - Mar 2026 | |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| Pharmaron | Coventry, RI | API Manufacturing |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| PMG Research | , | Now Acellacare |
| 3B BlackBio | Bhopal, India | PCR products |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| Sonavex | Baltimore, MD | Ultrasound |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| QT Ultrasound | , | Renamed QT Imaging |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Tolmar | Fort Collins, CO | Small Molecules |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| InnoVoyce | Boston, MA | ENT Lasers |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Kumuda | , | Website gone Mar 2023 |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| , | Acquired by Alcon, Sep 2025 | |
| Kelliop | Newark, CA | Diagnostic Reader |
| Theragenics | Buford, GA | Medical Devices |
| Tecomet | Lille, France | Case Design, CNC Machining, Finishing |
| Angiosonics | , | Shut down 2002 |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Metronomia | Munich, Germany | Consulting & Data Management |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Marpē Therapeutics | , | Professor sideline |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| , | Renamed Stelexis BioSciences | |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Etubics | , | Rolled into ImmunityBio |
| Boston Neurosciences | , | Website down Jun 2020 |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| , | Renamed PsiThera, Dec 2025 | |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| Maplehurst Genetics International | , | Website gone |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Ikotech | , | Closed Dec 2015 |
| , | Website down Jan 2026 - May 2026 | |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| DDL | Eden Prairie, MN | Device Testing |
| , | Website down Oct 2025 - Feb 2026 | |
| Ally Therapeutics | , | Shut down early 2021 |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| , | Website down Oct 2025 - Feb 2026 | |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Pfizer | Puurs, Belgium | Packaging |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| iThemba Pharmaceuticals | , | No information |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| , | Website down Dec 2025 - Apr 2026 | |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| , | Acquired by IQVIA | |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| Stemetix | , | Shut down Apr 2021 |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Omixon | Boston, MA | Next-gen sequencing products |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| Symansis | Timaru, New Zealand | Reagents |
| Oticon | Somerset, NJ | Hearing Aids |
| Gennova Bio | Pune, India | mRNA vaccine |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| Medipacs | , | Shut down Jul 2024 |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Abbott | Des Plaines, IL | Diagnostics |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| GeneSeek | , | Bought by Neogen |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| Valneva | Livingston, UK | Biologics Manufacturing |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Novartis | Emeryville, CA | Diagnostics |
| ORIG3N | , | Renamed Seaport Diagnostics |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Biosion | Nanjing, China | Bispecific Antibody |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| , | Website down Nov 2025 - Apr 2026 | |
| Xention | , | All programs halted or disposed of by 2016 |
| Terpenoid Therapeutics | , | Gone |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Ionpath | , | Shut down Feb 2025 |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Chromtech | Apple Valley, MN | Chromatography Products |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| Mindflow Design | , | Now part of MPE |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Monobind | Lake Forest, CA | IVD |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Azkarra Therapeutics | South SF, CA | Small molecule modulators of DNA damage response (DDR) pathways |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| , | Website down Jan 2026 - May 2026 | |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| ReSync Bio | , | Acquired by Benchling 2025 |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| Iquum | , | Acquired by Roche, Apr 2014 |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Biotagenics | , | Renamed MedBiome |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Getinge | Växjö, Sweden | Medical Technology |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| Align Technology | Tempe, AZ | Teeth alignment |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| Medtronic | Galway, Ireland | Medical Devices |
| Ottobock | Königsee, Germany | Prosthetics |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| EMS | Hortolândia, Brazil | Small Molecules |
| Duality Biologics | Shanghai, China | ADCs |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| CP Life Science | , | Split and became Medvacon |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| SK Biotek | , | part of SK pharmteco |
| Accutome | , | Now part of Keeler |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| , | Gone 2023, website taken over by a designer | |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| numares | Regensburg, Germany | Clinical Diagnostics |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| Root Lines Technology | , | Renamed Samabriva |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| Kinaxo | , | Bought by Evotec |
| Immune Technology Corp | New York, NY | Virology research products |
| X-Biotix Therapeutics | , | Website down May 2022 |
| , | Website taken over, Nov 2025 | |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Syngene International | Bangalore, India | Contract Research |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Targeson | , | Website gone, Mar 2017 |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Voitheia Bioscience | , | |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Strike Bio | , | Assets auction, Aug 2017 |
| Cellanome | Foster City, CA | Multiomics Platform |
| , | Merged with DefiniGEN to become pixl.bio | |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| NeuroSearch | , | Wound down 2012 |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| CellASIC | , | Bought by Millipore, May 2012 |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| Advarra | Columbia, MD | Regulatory Consulting |
| Accugent Laboratories | , | Website gone Sep 2017 |
| Angelica Therapeutics | , | Gone 2018 |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| MetaMol Theranostics | , | Gone |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |