| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
|
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
|
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Alizyme | , | Bankrupt 2009 |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| IncellDx | , | Renamed HealthBio AI |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| XO1 | , | Bought by J&J, Mar 2015 |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Elypta | Solna, Sweden | Liquid Biopsy |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| CellCarta | Montréal, QC | Clinical Research |
| Ecopharm | , | Website down Feb 2021 |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| Develco Pharma | Schopfheim, Germany | Generics |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Glenveigh Medical | , | Website down Sep 2024 |
| Stemetix | , | Shut down Apr 2021 |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Medtronic | Galway, Ireland | Medical Devices |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Sentien Biotechnologies | , | Shut down late 2021 |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| NetBio | , | Renamed ANDE |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| ExThera Medical | Martinez, CA | Blood filtration |
| , | Bankrupt, ceased operations Mar 2026 | |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| BioDatomics | , | Website gone Jan 2019 |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Nephros | South Orange, NJ | Dialysis Devices |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| TaiwanBio | , | Website gone Oct 2021 |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| , | Website redirecting to Talon Group, Jul 2026 | |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Tgen Tech | , | Renamed Annoviant |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics, CDMO |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| , | Renamed Aurevia | |
| Abnovel | , | Gone Jul 2010 |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| AliveDx | Eysins, Switzerland | Diagnostics |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| BenuBiopharma | , | Shut down Sep 2023 |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Audubon Bioscience | Houston, TX | Biospecimens |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| , | Website gone Aug 2026; All execs gone, Sep 2025 | |
| Acrongenomics | , | No info since 2013, seems gone |
| Prometheus Labs | San Diego, CA | Diagnostics |
| , | Filings late Jan 2026; No website May 2023 - Mar 2026 | |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| Proxima | New York, NY | AI Protein Folding Platform |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| Best Vascular | , | Now Best Vascular Novoste |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| , | Website taken over, Nov 2025 | |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| Vista.ai | Palo Alto, CA | MRI Software |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| Precursion Biosciences | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Simondr | , | Website gone, President has new job |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| OD-OS | Teltow, Germany | Retinal Laser |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| ID Pharma | , | Acquired by I'rom Group |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| Genex Pharma | Mumbai , India | Generics |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Pharma Medica | Toronto, ON | Clinical Services |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| JAMP Pharma | Boucherville, QC | Generics |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Tikcro Technologies | , | Liquidating 2021 |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| AMR Bio | Brighton, UK | Antimicrobials |
| Genovis | Cambridge, MA | Nanoparticles |
| Santen | Nara, Japan | Ophthalmics |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Pharminox | , | Website gone, Aug 2017 |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Oxis International | , | Renamed GT Biopharma |
| Validant | , | Renamed Eliquent Life Sciences |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Keenova | Hazelwood, MO | Small Molecules |
| Facile Therapeutics | , | Shut down Dec 2021 |
| RenovoRx | Mountain View, CA | Catheters |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| SERB Pharmaceuticals | Rosedale, Australia | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| IQVIA | Durham, NC | Clinical Research |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| Lavipharm | Peania Attica, Greece | Small molecules |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Syantra | Calgary, AB | Breast cancer blood test |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Akesis LLC | , | Bankrupt 2015 |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| , | Acquired by Agilent, Sep 2024; Mallinckrodt sold unit to Private Equity, Sep 2019, $135M + $40M note + $75M contingents | |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| Quratis | Cheongju, Korea | Vaccines |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Mitokine Bioscience | , | Seems to be a research library now |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| Streck | La Vista, NE | QC & Diagnostic Products |
| inDNA Research Labs | , | Shut down 2015 |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Summation Bio | , | Shut down May 2023 |
| Pharmaron | Louisville, KY | R&D Services |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| , | Website down Feb 2026 - Aug 2026 | |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Aegea Biotechnologies | , | |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| accuFD | , | Closed Dec 2017 |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| EuroAPI | Paris, France | API Production, CDMO |
| Repco Development Technologies | , | Renamed 3Dispense |
| Tecomet | Arab, AL | Orthopedics CNC Machining |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Liposonix | , | Bought by Medicis |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
|
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
|
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| , | Acquired by Tecan, Aug 2021 | |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Niagara Biosciences | , | No info, Aug 2022 |
|
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Supeira | , | Website gone Mar 2023 |
| Idience | San Francisco, CA | Cancer Therapies |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Yposkesi | , | part of SK pharmteco |
| CardioCreate | , | Shut Down Jun 2020 |
| SoftGenetics | State College, PA | Software for genetic analysis |
| , | Website down Nov 2025 - Apr 2026 | |
|
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Revvity | Waltham, MA | Diagnostics, Services |
| Kasocio | , | Liquidated, Dec 2019 |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| RelonChem | Cheshire, UK | Generics |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| Targeson | , | Website gone, Mar 2017 |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
|
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website taken over Jun 2026 - Aug 2026 | |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| CoaguSense | Fremont, CA | Coagulation monitor |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| , | Website down Dec 2025 - Apr 2026 | |
| , | Acquired by GNI Group, Jun 2026 | |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Teva | West Chester, PA | Small Molecules |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| , | Website down Aug 2025 - Jan 2026 | |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| BIOMODEX | , | Acquired by Mentice |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Chrono Therapeutics | , | Shut Down 2019 |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| , | No news 2019 - Apr 2026 | |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Biopar | , | Gone? |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Imalux | , | Ceased Operations, Apr 2014 |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Coeptis | , | |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Stago | Clarkston, GA | Diagnostics |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Medtronic | Warsaw, IN | Medical Devices |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| Agenus | Lexington, MA | Biologics, Vaccines |
| , | Shut down Mar 2026 | |
| Enlibrium | , | Gone 2018 |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| CSSi | , | |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Bracco | Milan, Italy | Imaging |
| Cetero Research | , | Renamed PRACS Institute |
| Acumed | Hampshire , UK | Medical Implants |
| Verici Dx | Cardiff, UK | Kidney Transplant Technology |
| Curadev | Noida, India | Immuno-oncology |
| , | Website down Dec 2025 - Jun 2026 | |
| , | Renamed EarliPoint Health, Oct 2025 | |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| , | Renamed Athens Bioscience, Mar 2026 | |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| RSIP Vision | San Francisco, CA | Image analysis algorithms |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Ribonomics | , | Sold to MBL International |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Marker Therapeutics | Houston, TX | Cell Therapy |
|
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Celregen | Hangzhou, China | iPSC |
| Valneva | Livingston, UK | Biologics Manufacturing |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Androclus Therapeutics | , | Closed, May 2007 |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
|
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
|
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| Evonik Industries | Birmingham, AL | Biomaterials |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| Acumed | Hillsboro, OR | Medical Implants |
| , | Acquired by Instem, Jul 2025 | |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| , | Rebranded as VivoSim, Apr 2025 | |
| Holloway America | Springfield, MO | Vessels, Tanks |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| ResearchDx | Irvine, CA | Diagnostics |
| Signalife | , | Renamed Heart Tronics |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Innerpulse | , | Gone maybe 2013 |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| Xcede Technologies | , | Gone Jun 2020 |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Arzeda | Seattle, WA | Computation protein design |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| BioVolutions | , | Gone |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Predictive Biosciences | , | Closed 2013 |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| , | Shut down Nov 2025, Tempus acquired assets | |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| PluroGen Therapeutics | , | Gone 2013 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Kumuda | , | Website gone Mar 2023 |
| Raze Therapeutics | , | Closed due to complicated biology |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| Validation Associates | Herndon, VA | Validation Consulting |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Clear Image Technology | , | Now CIT Ortho |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| NsGene | , | Website gone |
| SERB Pharmaceuticals | Hattiesburg, MS | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Ingenix | Warsaw, Poland | AI Engine Connection |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Provasculon | , | Website Gone, Apr 2014 |
| Weatherden | London, UK | Clinical Consulting |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| LemnaGene | , | Acquired by Biolex 2005 |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| argenx | Boston, MA | Antibody therapies |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Zars Pharma | , | Acquired by NuVo Research |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Sojournix | , | Shut down Jun 2021 |
| AMRI | , | Renamed Curia, Jul 2021 |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Castor | Claymont, DE | eClinical Trial Software |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| ICU Medical | San Clemente, CA | Disposable medical products |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Sopherion | , | Website taken over, Mar 2017 |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Roche | Basel, Switzerland | Diagnostics |
| SourceMDx | , | Assets Sold |
| VG Life Sciences | , | Shell company |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| Ennov | Paris, France | Software Solutions |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| , | Website down Nov 2025 - Mar 2026 | |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Norgine | Hengoed, UK | Specialty Pharma |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| America Stem Cell | , | Changed name to Targazyme |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| Crown Bioscience | San Diego, CA | Drug Development |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Persomics | , | Gone 2019 |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Bionsight | Seoul, Korea | Database For Research |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| GenoMatix | , | Acquired by Intrexon |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Terpenoid Therapeutics | , | Gone |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| DDL | Eden Prairie, MN | Device Testing |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Ho’ola Therapeutics | , | |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| EQL Pharma | Lund, Sweden | Generics |
| , | No news 2021 - Jul 2026 | |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Akela Pharma | , | Now PharmaForm |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| A&O Pharma | Efringen-Kirchen, Germany | Regulatory & Analytical Consulting |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Genlantis | , | Acquired by AMSBIO |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| CD Genomics | Shirley, NY | Genomics Services |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
|
Cheshire, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| , | Winding down Apr 2026 | |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| Altasciences | Harleysville, PA | Contract Research |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| TETmedical | Fair Haven, NJ | Nanomedicine company focused on in vitro diagnostics |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
|
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| , | Website down Nov 2025 - Apr 2026 | |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| , | Acquired by QOL Medical, Nov 2025 | |
| , | Stopped work Aug 2025, IP company | |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Cytel | Pune, India | Clinical software, statistical services |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| Sonus Pharma | , | Merged with Oncogenex |
| Ectycell | , | Part of Cellectis |
| OncoCell MDx | , | Renamed Immunis.AI |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| CorDx | San Diego, CA | Diagnostics |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Derma-Cell Research | , | Website gone Nov 2019 |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| RION | Rochester, MN | Exosome Therapeutics |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| Tryton Medical | , | Shut down Jan 2021 |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| Duramed | , | Acquired by Barr Labs 2001 |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Bio-Processing Alliance | , | Website now for a training company |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Siga | Corvallis, OR | Small Molecules |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| GeneEx | , | Now RevDia |
| Evestra | San Antonio, TX | Women's Health |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| Talis Biomedical | , | |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| Avance Clinical | Firle, Australia | Clinical Research |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| , | Website, Linkedin gone Jul 2026; Founder relocated and became postdoc | |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Alliqua | Langhorne, PA | Hydrogels |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| Profusa | Emeryville, CA | Real-time biosensors |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Synthon | , | |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| iWel | Exton, PA | Glucose Meters |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Plaxgen | , | Shut Down 2019 |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Getinge | Wayne, NJ | Medical Technology |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Savage Medical | , | Renamed Averto Medical |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Procos | Cameri, Italy | Contract Manufacturing |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Onyvax | , | Assets Apparently Acquired |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| , | Website down Feb 2026 - Jul 2026 | |
| ARx | Glen Rock, PA | Pharmacokinetic CRO |
| Pangea Pharmaceuticals | Fort Lauderdale, FL | Generics, B2 |
| XaTek | , | No news 2021 - Feb 2025 |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| , | Acquired by Source BioScience, Apr 2025 | |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| Mindshare Medical | , | Renamed RevealDx |
| Zai Lab | Suzhou, China | Small Molecules |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Savant HWP | , | Gone 2019 |
| Bicolor | Belfast, UK | Lab Assays |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Patrin Pharma | Skokie, IL | Generics |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| GenSure | Shijiazhuang, China | Diagnostics |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| Enci Therapeutics | , | No website, business suspended by NC |
|
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| NutrigeneAI Biotech | Hong Kong, China | Vascular Regeneration Platform |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| Altair Therapeutics | , | Shut down Feb 2011 |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| Karo Bio | , | Renamed Karo Pharma |
| , | Part of Genesis | |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| Vista Scientific | , | Shut down Dec 2015 |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| MicrofluidX | , | Renamed MFX |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Roche | Buonas, Switzerland | Diagnostics |
|
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| Redoxis | Lund, Sweden | Drug development CRO |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| CTK Biotech | Poway, CA | Diagnostics |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| GlycoRegImmune | , | Changed name to GRI |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| Streamline Scientific | Birmingham, AL | Molecular Technologies |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| Invibio | Cleveleys, UK | Implants |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| SineuGene | Beijing, China | Gene Therapy |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| , | Acquired by UCB, Jun 2026, $2B | |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| US Labs | , | Bought by Labcorp |
| Genta | , | Liquidation 2012 |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Agenix | , | Gone, Website taken over |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| , | Acquired by IQVIA | |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| , | Website gone Jan 2026 - Jul 2026; aka Weimou Biotechnologies? | |
| May Health | Paris, France | Ovulation Restoration Therapy |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
|
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
|
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| Mesoblast | New York , NY | Regenerative Medicine |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| , | Website down Jul 2025 - Dec 2025 | |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Mustang Bio | Worcester, MA | Immunotherapies |
| , | Acquired by hVIVO, Jan 2025 | |
|
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| , | Website down Oct 2025 - Feb 2026 | |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Grifols | Durham, NC | Biologics |
| T&T Scientific | , | Website gone May 2023 |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Medicure | Winnipeg, MB | Small Molecule |
| , | Website down Oct 2025 - Feb 2026 | |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Proteintech | Wuhan, China | Research Antibodies |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| LifeQual Pharmaceuticals | , | Website Gone |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Regulatory Pharma Net | Pisa, Italy | Regulatory Consulting & Market Access |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Zylacta | , | No news 2015 - Oct 2024 |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| JAJ International | , | Website not working, redirecting strangely |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| AblaCor | , | Shut down May 2019 |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| DDL | Irvine, CA | Device Testing |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
|
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| Macleods Pharmaceuticals | Gangtok, India | Generics |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| , | Website down Jan 2026 - May 2026 | |
| iBridge Medical | , | Website gone Jan 2020 |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Lux Biosciences | , | Gone |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Okairos | , | Acquired by GSK, May 2013 |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| SteriTech | Surrey, UK | Process Equipment |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Novotech | Auckland , New Zealand | Clinical Research |
| , | Renamed FocalTherics, May 2026 | |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| APIE Therapeutics | , | Gone Jun 2025 |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Samsara Sciences | , | Shut Down Mar 2020 |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| Axcend | Lehi, UT | Chromatography Services |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Trilobio | San Francisco, CA | Lab Automation |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| Metenova | ZZ, Sweden | Mixers |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Spine View | , | Gone |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
|
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Empatica | Milan, Italy | Seizure Detection |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| La Jolla Biologics | , | Website gone Nov 2014 |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Core Prognostex | , | Seems inactive |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Dipharma | Baranzate, Italy | APIs, Generics |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| COOL-BIO | , | Gone |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| Parsolex | , | |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| , | Pivoted to crypto, Apr 2026 | |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Promedior | , | Acquired by Roche, Feb 2020 |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| Sitka Biopharma | , | Website gone Jan 2022 |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
|
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Nucryst | , | Bought by Smith & Nephew |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| , | Website down Nov 2025 - Apr 2026 | |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Mighty Therapeutics | Needham, MA | Mitochondrial disease therapies |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
|
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Coley Pharma | , | Acquired by Pfizer |
| Sightera Biosciences | Antwerp, Belgium | Generative Drug Design |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Vascular Technology | Nashua, NH | Surgical Devices |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| , | Renamed First Atom Therapeutics | |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| Adynxx | , | Website taken over Sep 2020 |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| , | Merged with crypto company, Dec 2025 | |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| Carticept Medical | , | Dissolved Feb 2020 |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Cell Therapy Ltd | , | Renamed Celixir |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| Medtronic | Danvers, MA | Medical Devices |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
|
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website down Feb 2026 - Aug 2026 | |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| , | No news 2020 - Dec 2025 | |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Ergomed | Moscow, Russia | Clinical Research |
| , | Shut down Jul 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
|
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| , | Website down Jan 2026 - May 2026 | |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
|
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| PathoGene | , | Website taken over, Oct 2017 |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| , | No news 2020 - Apr 2026 | |
| Salvat | Miami, FL | Small Molecules |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Bionsight | Chuncheon, Korea | Database For Research |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| , | Gone 2023, website taken over by a designer | |
| Adlon Therapeutics | , | |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| PreciThera | , | Website taken over, Dec 2021 |
| Advanced Genetic Technologies | , | No info |
| , | Website down Dec 2025 - Apr 2026 | |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Embecta | Parsippany, NJ | Diabetes Care |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| Global BioDevelopment | , | Website gone |
| , | Website down Sep 2025 - Dec 2025 | |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Bankruptcy Oct 2024 | |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Actis Biologics | , | Gone |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| , | Website under construction Nov 2025 - Jul 2026 | |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Xeris Biopharma | Chicago, IL | Injectables |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
|
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| R/D Clinical Research | , | Website Gone |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| Transcera | Boston, MA | Extracellular Protein Degradation |
| HiMedia Laboratories | Thane, India | Microbiology Products |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Kegelbell | , | Shut down, Dec 2024 |
| , | Shut down Jan 2025 | |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| Bioasis Technologies | , | Closing down Jun 2023 |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
|
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| RSSL | Reading, UK | Analytical Services |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| Clarivate | London, UK | Vascularized organoids |
| superDimension | , | Acquired by Covidien May 2012 |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| Microsure | Son, Netherlands | Surgical Robots |
| , | Website down Dec 2025 - May 2026 | |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| CatSci | Cardiff, UK | Contract Research |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| , | No news 2017 - Apr 2026 | |
| Novometrics | , | Dissolved Dec 2019 |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Octane Biotech | Lucknow, India | Generics |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Surgisense | , | Presumed gone |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| DynoSense | , | Shut down Sep 2022 |
| Piramal | Ahmedabad, India | CDMO |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| , | Renamed Renew Biotechnologies, Jul 2026 | |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Neurotronik | , | Most employees moved to InnerPulse |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Telis Bioscience | , | Renamed Alvea |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| Rezo Therapeutics | San Francisco, CA | |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| , | Shut down Oct 2024 | |
|
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| On-Q-Ity | , | Closed 2013 |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| , | Website down Feb 2026 - Jul 2026 | |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| TheoremDx | , | Bankrupt Feb 2020 |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments, ADCs |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| M2 Medical | , | Now Asante Solutions |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Ocean Therapeutics | , | Shut down June 2013 |
| Circadiance | Export, PA | CPAP Mask |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Hypromatrix | , | Gone 2007 |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Evolve BioSystems | , | Renamed Infinant Health |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| PsiOxus Therapeutics | , | |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Genitope | , | Wound Down |
| Cambrian Genomics | , | Shut down Dec 2017 |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| DM Clinical Research | Houston, TX | Clinical Research |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Stemnovate | Cambridge, UK | Research Cells |
| Amniox Medical | , | Folded into BioTissue |
| Opentrons | New York, NY | Lab Automation Robots |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| Avomeen | , | Acquired by Element, Mar 2021 |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Axcella Health | , | Renamed Axcella Therapeutics |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Repligen | Waltham, MA | Protein Manufacturing Equipment |
| Vali Nanomedical | , | Gone 2016 |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Olymvax | Chengdu, China | Vaccines |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Hemanext | Lexington, MA | Transfusion Technologies |
| Deimos Biosciences | , | |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| Kura Oncology | San Diego, CA | Small Molecules |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Meta-Iq | , | Website gone Jun 2020 |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| , | Shut down May 2026, assets to Innoviva | |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| , | Website down Sep 2025 - Dec 2025 | |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Synfini | Menlo Park, CA | AI Drug Design |
| , | Website down Sep 2025 - Feb 2026 | |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Aimsn Medical | Hong Kong, China | Devices, Implants, First Aid |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| Rinat | , | Bought by Pfizer 2006 |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| Alacrity Biosciences | , | Gone post-2011 |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| APT Therapeutics | , | Shut down Mar 2019 |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| Novotech | Seoul, Korea | Clinical Research |
| Neurophet | Seoul, Korea | AI-Image Processing |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| Lusis | Hayward, CA | Diagnostics |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
|
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| , | Acquired by Castle Biosciences, May 2025 | |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Synomics | , | Now Smithers Pharma Services |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| , | Acquired by Medicover, Apr 2026 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
|
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Ribon Therapeutics | , | Shut down May 2024 |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Helus Pharma | Toronto, ON | Psychedelics |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| Hesperos | Orlando, FL | Human-on-a-chip |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| , | Listed as shutdown on Google, Linkedin gone Jul 2026 | |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Pierce | , | Part of Thermo Fisher |
| TrialStat Solutions | Montreal, QC | eClinical |
| RK Pharma | Pearl River, NJ | Generics |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Regulome | , | Gone 2006 |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| Affinimark Technologies | , | Gone |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
|
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Medicomp | , | Renamed ReactDx |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| Medispect | , | Shut Down 2013 |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Piramal | Rabale, India | CDMO |
| VWR | Radnor, PA | Lab Products & Chemicals |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Sermes | Madrid, Spain | Full Service CRO |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Manhattan Pharmaceuticals | , | Gone |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Signant Health | Horsham, PA | eClinical Solutions |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| MediLink Therapeutics | Suzhou, China | ADC |
| rhealth | Bedford, MA | Diagnostics |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Avaxia Biologics | , | IP acquired by Circle33 |
| Invivyd | New Haven, CT | Therapeutic Antibodies |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Bioneeds | Bangalore , India | Contract Research |
|
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| , | Acquired by Instem, Jul 2025 | |
| Accellacare | Downers Grove, IL | Clinical Research |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| , | Subsumed into parent, Jul 2026 | |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| Bionovis | Valinhos, Brazil | Biosimilars |
| Viwit | Shanghai, China | APIs, Formulation |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| CultureTrax | , | Shut Down Dec 2019 |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Abbott | Alameda, CA | Diabetes Care |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Karius | Redwood City, CA | Diagnostics |
| Omixon | Boston, MA | Next-gen sequencing products |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Molecular Detection Inc | , | Gone 2016 |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| MSD | Ballydine, Ireland | Small Molecules |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| , | Website down Jan 2026 - May 2026 | |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Zhejiang Medicine | Shaoxing, China | Generics |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Anacalypsis Therapeutics | Spata, Greece | LRRK2 Targeting Therapies |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| XtalPi | Shanghai, China | AI Drug Design |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Metrad Biosystems | , | Website gone |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| Genemo | , | Seems inactive, Jul 2024 |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| oRF Biologics | Tiffin, IA | Custom biologics, cells, media, antibodies, resins |
| Apotex | Toronto, ON | Small Molecule Generics |
| Apollo Spine | , | Renamed G6 Spine |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Astrum | Paris, France | Clinical Development CRO |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| , | Website down Jul 2025 - Dec 2025 | |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| DNAtrix | , | Gone late 2023 |
| , | Acquired by Artis Biosolutions, Apr 2025 | |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| X-Rx | , | Shut down Jun 2020 |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| Sierra Neuropharmaceuticals | , | Not active |
| Immerge BioTherapeutics | , | Founded 2000 |
| Maroon Biotech | , | Gone Sep 2010 |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| Curamir Therapeutics | , | Shut down 2020 |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| Verici Dx | Franklin, TN | Kidney Transplant Technology |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| SereDigm | , | Gone Nov 2009 |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| MicroVention | , | Now Terumo Neuro |
| Cambridge Pharma | , | Rolled into parent, SMC |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
|
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| , | Website down Dec 2025 - Apr 2026 | |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| CanBas | Shizuoka, Japan | Small Molecules |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
|
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| X-Biotix Therapeutics | , | Website down May 2022 |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
|
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| PepVax | , | Gone 2024 |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| , | Website down Oct 2025 - Feb 2026 | |
| , | Website down Jul 2025 - Oct 2025 | |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| NeuExcell Therapeutics | King of Prussia, PA | Gene Therapy for Neural Regeneration & Repair |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
|
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| PolyTherics | , | Joined Antitope to become Abzena |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Aztech Sciences | , | Website gone Jun 2021 |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| Apnex Medical | , | Shut down, Aug 2013 |
| , | Acquired by Hologic, Jan 2025, $350M | |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| , | CEO left 2020, still on website Dec 2025 | |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| Takara Bio USA | San Jose, CA | Lab products |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Myoposity Therapeutics | , | Gone |
| Santen | Osaka, Japan | Ophthalmics |
| ProPharma Group | Deerfield, IL | Consulting |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| Tecomet | Baden-Dattwil, Switzerland | Bone In-Growth Coating, Bearing Surface Solutions, Polymer Machining, Sterilized Packaging |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Aethox Therapeutics | London, UK | Inhibitors |
| Azkarra Therapeutics | South SF, CA | Small molecule modulators of DNA damage response (DDR) pathways |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Madeira Therapeutics | , | Gone. No info |
| AngioCure | , | Employees all gone, Nov 2017 |
| , | Gone Jan 2026 | |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
|
Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Proteintech | Rosemont, IL | Research Antibodies |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Veeva Systems | Radnor, PA | Life Science Software |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| HawkCell | Lyon, France | MRI Research Technology |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| EMKinetics | , | Seems inactive Feb 2021 |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| , | Website down Oct 2025 - Feb 2026 | |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| GenQual | , | Inactive, Jun 2017 |
| Pharmanovia | London, UK | Acquisition of Drugs |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Elucid | Boston, MA | Arterial Analysis Software |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Jetequip | Boucherville, QC | Fluid Handling |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Proteotech | , | Website gone Jul 2015 |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Activ Surgical | Boston, MA | Surgical Software |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Nanostream | , | Closed Mar 2008 |
| Sciele Pharma | , | Bought by Shionogi |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| , | Shut down Jan 2026 | |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Adepthera | , | Shut down 2014 |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| preclinics | Eystrup, Germany | Contract Research |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Piramal | Pithampur, India | CDMO |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| CNCure | Seoul, Korea | Tumor-targeting Bacteria |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| FocalTherics | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| Celvive | , | No news from 2012-2020 |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Abolis Biotechnologies | Evry-Courcouronnes, France | Microbial engineering to produce biosourced small molecules |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| , | Renamed KadisBio | |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| GSK | Rueil-Malmaison, France | Small Molecules, Vaccines, Biologics |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Arstasis | , | Appears Gone Sep 2017 |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| SynAm Vaccine | , | Gone 2017 |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Ignis Therapeutics | Shanghai, China | |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| , | Website down Feb 2026 - Jul 2026 | |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Collgard Biopharmaceuticals | , | Gone |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| MicroPort | Clamart, France | Medical Devices |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Zephyr AI | McLean, VA | AI Data Analysis |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| iuvo | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| APCRA | , | Shut down 2020 |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| FocalTherics | Vaulx-en-Velin, France | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
|
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| Redpoint Research | , | Gone 2019 |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| ZyStor | , | Bought by BioMarin, closed |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Snorx | , | Renamed Zelegent, May 2015 |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Senlang Biotechnology | Hebei, China | Cell Therapy |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| Applied Therapeutics | New York, NY | Small Molecules |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| , | Website down Feb 2026 - Jul 2026 | |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| , | Acquired by IMA Group, Oct 2025 | |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Aikium | Berkeley, CA | AI Drug Discovery |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| InnoCare | Beijing, China | Cancer Treatments |
| , | being Acquired by Chugai, Oct 2025 | |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Algenix | , | MN Business revoked, Mar 2004 |
| Tanai Therapeutics | , | Obesity Treatment |
| Inventiva | Daix, France | Small Molecules |
| Predicine | Hayward, CA | Liquid Biopsy |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Avail Medsystems | , | Tech sold Mar 2024 |
| , | Acquired by Beacon Biosignals, Apr 2025 | |
| Amarin | Dublin, Ireland | Small Molecules |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Synergx | , | Owned by Morphogenesis |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| Pharos Dx | , | Gone |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Proacta | , | Gone 2014 |
| Scinomix | Earth City, MO | Lab Automation Products |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Jade Biosciences | Virtual, US | Biologics for Autoimmune Diseases |
|
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Alkem Labs | Mumbai, India | Generics |
| Michrom | , | Bought by Bruker, Feb 2011 |
| Eco Quest | , | Now Cynata Therapeutics |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| Innogen Pharmaceuticals | Shanghai, China | GLP-1, Biologics |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Summit Therapeutics | Palo Alto, CA | Utrophin modulation technology |
| QL Biopharm | Beijing, China | Biologics |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| toSense | , | Acquired by Baxter, Jun 2020 |
| OmniGuide | Billerica, MA | Surgical technology |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| , | Liquidating, May 2026 | |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| iCeutica | , | Seems gone, Jan 2022 |
| Stago | Marseille, France | Diagnostics |
| Roche | Schlieren, Switzerland | Small Molecules |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| CorePharma | Middlesex, NJ | Contract Small Molecule Manufacturing |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| Diality | Irvine, CA | Hemodialysis System |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Diex Recherche | Sherbrooke, QC | Clinical Site |
| Prolexys Pharmaceuticals | , | Website Gone |
| Alimentiv | San Diego, CA | Clinical Services |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Mendaera | San Mateo, CA | Medical Robotics |
| 3T Biosciences | South SF, CA | TCR Therapies |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Advanced Peptides | , | No business filings since 2011 |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Proteins and Peptide Management | , | Now Adocia |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Nephrion | , | Closed 2006? |
| Isis Biopolymer | , | Website taken over |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| , | Main employees gone for months as of Nov 2025 | |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| , | Website down Jul 2025 - Dec 2025 | |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| , | Website down Jan 2026 - May 2026 | |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Accellix | Jerusalem, Israel | On-demand Assays |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| , | Website down Jun 2025 - Dec 2025 | |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| iThemba Pharmaceuticals | , | No information |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| Synergen | , | Bought by Amgen 1994 |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| Medion Diagnostics | , | Bought by Grifols? |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
|
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| , | Crypto Pivot, Oct 2025 | |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Logan Medical Devices | , | Gone? |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Innomab | , | Gone 2017 |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| , | LI gone Jul 2026; Filings late Nov 2023 - Jul 2026; fka Gala Therapeutics | |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Lacerta Therapeutics | , | Shut down May 2024 |
| Kvvit Pharmaceutical | , | |
|
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Neuron23 | South SF, CA | AI-drug discovery |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Pfizer | McPherson, KS | Sterile Injectables |
| QuA Vodis | , | Gone |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| MindWalk | Victoria, BC | Custom Antibodies |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Vanguard Therapeutics | , | |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| , | Renamed Singulera, Nov 2025 | |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| SaluMedica | , | Website Gone Jul 2015 |
| , | Part of Greenpharma | |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| Aeres Biomedical | , | Gone Jul 2013 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| NorthernBio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| Trillium Diagnostics | , | Closed Jul 2016 |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Compliment Corporation | , | Closed Dec 2011 |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| , | Bankruptcy, Jun 2026 | |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| , | Website down Feb 2026 - Jul 2026; filings Late Jun 2024 - Dec 2025 | |
| Inno Biologics | , | Website gone Jun 2020 |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| , | Website down Oct 2025 - Feb 2026 | |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| NEC Oncoimmunity | , | Renamed NEC |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Western States Biopharmaceuticals | , | Website Taken Over |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| , | Website down Feb 2026 - Jul 2026 | |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| , | Website down Dec 2025 - Apr 2026 | |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| XStalBio | , | Folded |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Blackfynn | , | Gone Apr 2022 |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| , | Website down Feb 2026 - Jul 2026 | |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| AIBioTech | , | Assets auction, Aug 2017 |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| , | Acquired by Biogen, May 2026, $5.6B | |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| SK Biotek | , | part of SK pharmteco |
| arGEN-X | , | Older name for Argenx |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Alanex | , | Acquired by Agouron, Apr 1997 |
|
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| NanoSort | , | Renamed NanoCellect |
| Gensco Pharma | Doral, FL | Transdermals |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| CanTx | , | Website gone, Feb 2015 |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| NeuroNano Pharma | , | Gone 2018 |
|
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| BioVascular | , | 2007 website as of Mar 2019 |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| LC Technologies | , | Renamed EyeGaze |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| , | Renamed Mobia Medical, Feb 2026 | |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| Sharp | Macungie, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| Singulex | , | Shut down Jun 2019 |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Ergomed | Surrey, UK | Clinical Research |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Oxitope | , | Shut Down Feb 2019 |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| , | Shut down Mar 2026 | |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| AstraZeneca | Baar, Switzerland | Biologics |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| , | No news 2021 - Jan 2026 | |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Nova Biomedical | Norwood, MA | Lab instruments |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| , | Acquired by BioIVT, Aug 2024 | |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Xegen | Gemenos, France | NGS Data Analysis |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| , | Acquired by SERB Specialty, May 2020 | |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| BBOT | South SF, CA | RAS-targeted small molecules |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Osteologix | , | Liquidated, Sep 2015 |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Statera Therapeutics | , | Shut down Jan 2022 |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| , | Website down Sep 2025 - Dec 2025 | |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Blansett Pharmacal | , | Gone Jan 2019 |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
|
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Nymirum | , | Renamed Base4, Feb 2023 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| , | Website down Dec 2025 - Feb 2026 | |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Large Scale Biology | , | Shut Down |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
|
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| Heart Tronics | , | Effectively defunct after scandal |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Genetron Health | Beijing, China | Diagnostics |
| , | Website down Mar 2026 - Aug 2026 | |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| Genera Medix | , | Apparently sold all products |
| , | Website down Feb 2026 - Jul 2026 | |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
|
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| TissUse | Berlin, Germany | Multi Organ chip |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Solstice Oncology | , | |
| , | Website down Dec 2025 - Apr 2026 | |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| Lucena | , | Failed |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| OriMAbs | , | Gone post 2022 |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics, CDMO |
|
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| ECI Biotech | , | Gone 2016 |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| American Drug Co. | , | Renamed Five Star Products |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| BioSyntech | , | Bought by Piramal |
|
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| STX-Med | , | Renamed Cefaly |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| , | Website down Nov 2025 - Apr 2026 | |
| Metronomia | Munich, Germany | Consulting & Data Management |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| Ceronco Biosciences | , | Gone 2015? |
| Applied NeuroSolutions | , | Gone |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Elegen | San Carlos, CA | DNA writing |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Abogen | Suzhou, China | mRNA |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Allumiqs | Halifax, NS | Multiomics CRO delivering NULISA, LC-MS/MS, biomarker discovery and data insights. |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Quantum SI | Branford, CT | Single-molecule NGS |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| , | Acquired by Artis Jun 2026 | |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| , | Website down Jan 2026 - May 2026 | |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Aytu BioScience | , | now Aytu BioPharma |
| Sharp | Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Rad AI | San Francisco, CA | Radiology Software |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| Calchan | , | Shut down Dec 2020 |
| Cyberval | , | Seems inactive Feb 2024 |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| Accro Bioscience | Suzhou, China | Small Molecules |
| , | Renamed BreezeBio, Feb 2026 | |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| CareDx | Brisbane, CA | Diagnostics |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| , | Merged with Vizgen, Oct 2024 | |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| , | Linkedin gone Jul 2026; Website down Jun 2026 - Jul 2026; Cyrus Biotechnology spinout | |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Anesiva | , | Bankrupt 2010 |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
|
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| , | Website down Jul 2025 - Jan 2026 | |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| CereScan Corp | , | Renamed CereHealth |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| KeraCure | , | Gone 2014 |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| Tecomet | Manchester, NH | Case Design, CNC Machining, Injection Molding, Metal Forming, Vacuum Forming |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| MakroCare | San Francisco, CA | Drug Development Partner |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| BioParadox | , | Shut down Dec 2017 |
| EpiFinder | , | Gone May 2025 |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Zumutor Biologics | Bangalore, India | Biologics |
| Proveri | , | Gone 2016 |
| SDC | Higley, AZ | Clinical Data Services, Virtual Trials |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| NuAire | Plymouth, MN | Lab Equipment |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| BridGE Genomics | , | Gone 2022 |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| , | Company gone Nov 2023, website taken by a game | |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| 206 Ortho | , | Shut down 2021 |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| , | Acquired by Novacyt Group | |
| , | Website taken over, Jan 2026 | |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| ViraCyte | , | Renamed AlloVir |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Expression Patholgy | , | Now OncoPlexDx |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Michigan Clinical Research Institute | , | |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Accellacare | Hickory, NC | Clinical Research |
| Griffin Laboratories | , | Acquired by Atos Medical |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| , | Website down Nov 2025 - Apr 2026 | |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| , | ||
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| GlySens | , | Bankrupt Nov 2022 |
| Immutics | , | Renamed TrueBinding |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Omniseq | , | Acquired by LabCorp, 2021 |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Abcam | Cambridge, UK | Antibodies |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| , | Renamed Motive Health, Jul 2023 | |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Quellthera | , | Subsumed into Liveleaf |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| ImmuneWorks | , | Website gone, Apr 2018 |
| InterGenetics | , | Assets auctioned |
| , | Liquidated 2024 | |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Parexel | Sheffield, UK | Clinical Research |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| GT Molecular | Fort Collins, CO | PCR Kits |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Amorsus | , | Website Gone 8-30-13 |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| Gene Signal | , | Bankrupt, Apr 2021 |
| Northfield Laboratories | , | Bankrupt 2009 |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Neocis | Miami, FL | Dental Surgery Robots |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Starkey | Eden Prairie, MN | Hearing Aids |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| , | Website down Jun 2025 - Dec 2025 | |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Neuroptix | , | Renamed Cognoptix |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Veeva Systems | Toronto, ON | Life Science Software |
| Imcyse | , | Liquidating, Jun 2025 |
| Ipsen | Dublin, Ireland | Small Molecules |
| TransGenRx | , | Bankrupt |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
|
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| , | Gone Jan 2025 | |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| DxNow | , | Renamed ZyMot fertility |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| Rezolute | Redwood City, CA | Biologics |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| NeoTrail Therapeutics | , | |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| GeNO | , | Renamed Vero Biotech, 2018 |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| Lavipharm | East Windsor, NJ | Small molecules |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| , | Shut down May 2026; Filed Chapter 11 bankruptcy Sep 2019 | |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Gene Labs | , | Bought by GSk 2008 |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| Trophea Development | , | Liquidated Dec 2019 |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| PulmoGeniX | , | No business filings 2016-2020 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Aixlie Pharmaceuticals | , | No idea what happened |
| Gene Logic | , | Bankrupt |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| , | Website taken over Jun 2026 | |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
|
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Owkin | New York, NY | AI for Medical Research |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| Kailo Pharma | , | |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| , | Website down Jan 2026 - Mar 2026 | |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Serica Technologies | , | Bought by Allergan |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Virco | , | Bought by J&J |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| OperaCRO | , | Now part of Tigermed |
| Cebix | , | Shut down, Feb 2015 |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| Lannett | Trevose, PA | Generic Small Molecules |
| Getinge | Vendôme, France | Medical Technology |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| , | Renamed Cyaris, Apr 2026 | |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| Clontech | , | Now Takara Bio |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| VIVUS | Campbell, CA | Small Molecules |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Phenoquest | , | Website gone, Oct 2015 |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| , | No news 2020 - Jul 2026 | |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| , | Pandemic era government spongers | |
| , | Acquired by Millipore, Dec 2010 | |
|
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| , | Website down Jun 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| AmProtein | , | Presumed Gone |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| , | Website taken over Jun 2026 | |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Novacea | , | Bought by Transcept |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
|
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Remora Therapeutics | , | Shut down 2021 |
| AniLocus | Germantown, MD | Preclinical CRO |
| Niche Generics | Hitchin, UK | Contract Generics |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| Meissner | Camarillo, CA | Lab Systems |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Almac | Durham, NC | Pharmaceutical Services |
| Apicore | Gujarat, India | API Development & Manufacturing |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Chesapeake Biological Labs | , | Now known as Cangene |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| NeuroTransit | , | Behind on taxes in CA |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| Aerogen | Galway, Ireland | Nebulizers |
| Nereus | , | Website Gone late 2013, no info |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| , | Renamed NeuraNova, Jan 2026 | |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| Neuronax | , | Renamed Axoltis Pharma |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| PhotoThera | , | Ceased operations Dec 2012 |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| , | Website down Oct 2025 - Feb 2026 | |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| Gastrotech | , | Now Rose Pharma |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| VAXX | , | Not sure what happened to them |
| Suvoda | Portland, OR | Clinical Trial Software |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Verix Health | , | Renamed Serpex Medical |
| NextPharma | London, UK | Contract Research & Development |
| Abviva | , | Gone, 2008 |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| BASF Bioservices | , | Exited business, Sep 2025? |
| , | Website down Jan 2026 - May 2026 | |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Elixir Medical | Milpitas, CA | Stents |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| , | Website down Feb 2026 - Jul 2026 | |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| Intelliseq | Kraków, Poland | Genome Informatics |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Calcionics | , | Shut down 2010 |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
|
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Calmune | , | Liquidated |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| Solano Pharmaceuticals | , | Website gone |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| , | Dissolved Jun 2019 | |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| , | Acquired by Bruker, Sep 2020 | |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Texcell | Evry, France | Contract Research |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| Quench Bio | , | Wound down Mar 2021 |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Regulaxis | , | No news 2020-2024 |
| , | Acquired by Bausch + Lomb, Mar 2026 | |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| Meissner | Castlebar, Ireland | Lab Systems |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
|
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Octapharma | Springe, Germany | Plasma Products |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| Aracea Therapeutics | , | No website Aug 2022 |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| , | Website messed up, single employee, Dec 2025 | |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Spyryx Biosciences | , | Shut down 2019 |
| Synostics | , | Gone 2014 |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| , | Acquired by Altivera Medical, Mar 2026 | |
| IR2Dx | , | Gone, 2019 |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| OSI Pharmaceuticals | , | Bought by Astellas |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| South Coast Clinical Trials | , | Website gone |
| CO.DON | Leipzig, Germany | Cell Therapies |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
|
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Stimwave | , | Bankrupt, Oct 2022 |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| Celerion | Vienna, Austria | Clinical Research |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| ResMed | San Diego, CA | Medical Devices |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Apharm | , | Now Biofarma Group |
| Paige | New York, NY | AI Pathology |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| DDi | Basel, Switzerland | Clinical Software |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Stago | Maastricht, Netherlands | Diagnostics |
| Biobase | , | Bought by Qiagen, May 2014 |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| StemPar Sciences | , | Website disappeared, no news |
| amcure | , | Liquidated Sep 2024 |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| , | Subsumed into Cumulus Oncology | |
| Novian Health | Evry, France | Device for breast tumor ablation |
| , | Website down Sep 2025 - Feb 2026 | |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| ThauMDx | , | Closed down 2003, out of cash |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
|
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| MSD | Carlow, Ireland | Vaccines |
| , | Percutaneous ventricular assist device | |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
|
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
|
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Alcon | Mississauga, ON | Eye Care Products |
| XellSmart | Shanghai, China | Cell Therapy |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Novo Nordisk | Tokyo, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| Élancé Therapeutics | , | Bispecific Antibodies |
|
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Roxall | , | No news 2019 - May 2025 |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Tecomet | Wilmington, MA | EDM, Ultrasonics, Electrical Beam Welding, Vacuum Brazing |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Invenra | Madison, WI | Antibodies and their derivatives |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Nostrum Laboratories | Kansas City, MO | Generics |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Thermo Fisher | Bend, OR | CDMO |
| TG Therapeutics | Morrisville, NC | Biologics |
| Grove Instruments | , | Shut Down June 2017 |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| , | Merged with Yarrow Bioscience, Jul 2026; fka Menlo Therapeutics | |
| Benchling | San Francisco, CA | Biotech Software |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| Ergomed | Prague, Czech Republic | Clinical Research |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| GeneFab | Alameda, CA | Gene Therapy Services |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Autotelic | , | Gone 2022 |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| , | Website down Oct 2025 - Feb 2026 | |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| , | Website down Jan 2026 - May 2026 | |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Cyto360 | , | Website gone Aug 2018 |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Endotis Pharma | , | Founded in 2003. No info |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| , | Website down Aug 2025 - Jan 2026 | |
| , | Website down Jun 2025 - Dec 2025 | |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| Absynth Biologics | , | Website Gone Jan 2019 |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| BioLegacy Research | San Diego, CA | Contract Research |
| Omeros | Seattle, WA | Small Molecules |
| OPIS | Milan, Italy | Clinical Research, Consulting |
|
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Glenmark | Mumbai, India | Generic Small Molecules |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| , | Website down Oct 2025 - Feb 2026 | |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| DoveTree Medicines | , | |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Nteryx | , | Changed name to Ardelyx |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Envision Genomics | , | Website gone Nov 2019 |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Lindus Health | London, UK | CRO |
| , | Renamed Novakand Pharma, Sep 2025 | |
| , | Website taken over Jul 2026 - Aug 2026 | |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Stealth Therapeutics | , | Gone |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| ReproSource | Marlborough, MA | Fertility Testing |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| , | Website down Feb 2026 - Jul 2026 | |
| Sanofi | Midrand, South Africa | Biologics |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| , | Founder, Principal gone Sep 2024 | |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Metamark Genetics | , | Shut down 2018 |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| imarc | , | Acquired by Avania, Jun 2021 |
| , | Acquired by Eclipsebio, Jan 2026 | |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Delpharm | L'aigle, France | Contract Manufacturing |
| , | Acquired by Alfasigma, Nov 2023, $800M | |
| BZL Biologics | , | Gone 2003 |
| ArgusEye | Linköping, Sweden | Biosensors |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Catawba Research | Charlotte, NC | Clinical Research |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| , | Renamed Orvida Pharma, Apr 2026 | |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| AGILeBiotics | , | Shut down 2024? |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| Pharmascience | Montréal, QC | Generics |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Cellcion | , | Website gone, company going inactive |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Strike Bio | , | Assets auction, Aug 2017 |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Adheren | , | Gone, 2016 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| A2IDEA | , | Only employee left Jan 2024 |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Vivacy | Archamps, France | Aesthetic Medicine |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| SynGenSys | Sheffield, UK | DNA, Cell Products |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Serometrix | , | More of an aspiration than a company |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Bafna | Chennai, India | Generics |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| NTRC | , | Now Oncolines |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| GnuBIO | , | Bought by Bio-rad |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Biotrofix | , | Gone, Dec 2014 |
| XtalPi | Shenzhen, China | AI Drug Design |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| , | Website down Nov 2025 - Mar 2026 | |
| CyBio | , | Merged into Jena, Jul 2014 |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Ottobock | Duderstadt, Germany | Prosthetics |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| 121 Bio | , | Gone mid 2016 |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Aranscia | Houston, TX | Diagnostic Software |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| , | Website down Sep 2025 - Dec 2025 | |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| BaseCure Therapeutics | , | |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| GeneProt | , | Shut down Apr 2005 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Boston Scientific | Marlborough, MA | Medical Devices |
| Eos Biotechnology | , | Gone 2005 |
| Septerna | South SF, CA | GPCR Drug Discovery |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Baxter | Grosotto, Italy | Medication Delivery |
| PLC Medical Systems | , | Renamed RenalGuard |
| Atlas Genetics | , | Renamed Binx Health |
| Sharp | Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| TamRx | , | Website taken over Aug 2020 |
| Keenova | Dublin, Ireland | Small Molecules |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| Remedium Bio | Needham, MA | Gene Therapy |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| , | Renamed Allotera Therapeutics, Jul 2026 | |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Veryan Medical | Horsham, UK | Helical Stent |
|
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Website down Aug 2026; Acquired by Novo Nordisk, May 2024, $1.1B | |
| Beacle | , | Founder gone, no info |
| PluriCell | , | Renamed LizarBio |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| OncoQr | , | No news 2017 - Oct 2024 |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Medrobiotics | , | Bankrupt, May 2024 |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| AerovectRx | , | No news since 2006, Website gone |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| , | Website down May 2026 - Jul 2026; LI gone Jul 2026 | |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| Resilience | Hamilton, OH | Biomanufacturing |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| , | Website down Jun 2025 - Dec 2025 | |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Molecular Logix | , | Gone, Dec 2018 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Menarini | Florence, Italy | Biologics |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Medistem | , | Bought by Intrexon Dec 2013 |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| Octapharma | Lingolsheim, France | Plasma Products |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| Eargo | San Jose, CA | Hearing Aids |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| Alerchek | , | Closed late 2016 |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| DermaRite | North Bergen, NJ | Foam Dressing |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Piramal | Mumbai, India | CDMO |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Trigemina | , | Shut down Aug 2020 |
| Staburo | Munich, Germany | Clinical Services |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Parexel | Durham, NC | Clinical Research |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Apollomics | Xiaoshan, China | Cancer medicines |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Amarin | Bridgewater, NJ | Small Molecules |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| Zevra Therapeutics | Boston, MA | Modifications of Existing Drugs |
|
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Kylin Therapeutics | , | Sold |
| Lean Biologix | Norfolk, MA | Consulting |
| HiMedia Laboratories | Kennett Square, PA | Microbiology Products |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| Protypia | , | |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| Celixir | , | Shell acquired Dec 2023 |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| Torpedo Bio | , | |
| Tecomet | Oregon City, OR | Contract Medical Device Work |
|
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Lian Medical | Shanghai, China | Medical Devices |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| AniTech Limited | Hong Kong, China | AI-EEG Platform |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Bausch Health | Bridgewater, NJ | Small Molecules |
|
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| SVBio | , | Changed name to Lifecode |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Akrivis Technologies | , | Gone Jun 2021 |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Solventum | Eagan, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Novartis Animal Health | , | Acquired by Lilly |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| Altasciences | Laval, QC | Contract Research |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Tecomet | Holt, MI | Additive Manufacturing, Forging - Orthopedics |
| , | Website down Jan 2026 - May 2026 | |
| Allergenics Inc | , | Closed Mar 2007 |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| ASIT Biotech | , | Renamed DMS Imaging |
| Elite Research Institute | , | Gone, May 2018 |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Celsense | , | Shut down Dec 2021 |
| RadioRx | , | Now EpicentRx |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| , | Website down Dec 2025 | |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| , | Website down, Dec 2025 - Jun 2026 | |
| Ipsen | Sumter, SC | Biologics |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Scintillant Bioscience | , | Gone May 2025 |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| , | Renamed Biocult, Jul 2026 | |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Venta Medical | , | Gone, Apr 2017 |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
|
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Eternans | , | Shut down Jul 2022 |
| Rosedale Medical | , | Now Intuity Medical |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| , | ||
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| LENSAR | Orlando, FL | Cataract Laser |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Neoantigenics | , | Website gone Sep 2017 |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| , | Acquired by Biogen, Jun 2026, $1B milestones | |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Syngene International | Bangalore, India | Contract Research |
| MyoSyntax | , | Gone 2021 |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| Azano Biotech | , | Now Sandia Biotech |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Velia Therapeutics | , | Shut down Jan 2025 |
| Antara Biosciences | , | Bankrupt 2007 |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| Proteome Sciences | Surrey, UK | Proteomics |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Mastel Surgical | Schiller Park, IL | Surgical Devices |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| ImmBio | , | Shut down Nov 2019 |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Resilience | Blue Ash, OH | Biomanufacturing |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| DyNAbind | , | Shut down Apr 2025 |
| Phoresa | , | Shut down Mar 2018 |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| Skylit Medical | , | Renamed Clarify medical |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Alexis Biotech | , | Dissolved May 2015 |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Nocimed | , | Renamed Aclarion |
|
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| Angiomics | , | Product being sold by another company |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Iquum | , | Acquired by Roche, Apr 2014 |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Nexus BioPharma | , | No news 2017-2022 |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| Tolerx | , | Shut Down 2011 |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| Nigra | , | Acquired by Vernalis |
| Ileo Science | , | Seems gone Mar 2022 |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| Amresco | , | Acquired by VWR, Feb 2011 |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Perlara PBC | , | Shut down Feb 2019 |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| , | LI gone Jul 2026; Website down May 2026 - Jul 2026; fka Mynosys Cellular Devices | |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| GMP-Orphan France | , | Renamed Orphalan |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| Ossur | Irvine, CA | Orthopedic Devices |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| XBiotech | Austin, TX | Antibody Therapy |
| , | No news 2020 - Dec 2025 | |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| PowderMed | , | Acquired by Pfizer 2006 |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Noucor Health | Barcelona, Spain | Small Molecules |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| Macleods Pharmaceuticals | Pithampur, India | Generics |
| RegenoCELL Therapeutics | , | Presumed gone |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| Breathometer | , | Product didn’t work, pivoted |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| Weatherwax | , | Renamed General Proximity |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
|
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| , | Acquired by Immedica, Feb 2025 | |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Tuevol Therapeutics | , | Gone by 2020 |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| , | Acquired by IQVIA | |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| US Genomics | , | Now PathoGenetix |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| Furong Biotech | , | |
| Flownamics | Madison, WI | Automated Sampling |
| Celerion | Tempe, AZ | Clinical Research |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Pharmion | , | Acquired by Celgene 2007 |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| EPISONA | , | Gone Nov 2018 |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| , | Acquired by Aurinia Pharmaceuticals, Mar 2026; Assets spun out of Onyx Pharmaceuticals | |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| medac pharma production | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| Molecular Throughput | , | Rebranded as mtibio |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| , | Renamed Numerion Labs, Oct 2025 | |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Biomoles | , | Closed Sep 2017 |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| Tigris Pharmaceuticals | , | Now Kirax |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Alera Labs | Durham, NC | Contract Research & Services |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Altravax | , | Shut down 2016 |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| , | Linkedin gone Jul 2026; Website down Mar 2026 - Jul 2026; Not positive on drug types | |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| , | Website down Feb 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Platelet BioGenesis | , | renamed PlateletBio |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Waters | Milford, MA | Chromatography & Chemistry |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| Ionian Technologies | , | Gone Mar 2016 |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Tecomet | Chelsea, MI | CNC Machining, Polymer Machining, Orthopedics |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Mepha | Basel, Switzerland | Generics |
| Cobalis | , | Basically Bust |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Beta Pharma | Princeton, NJ | Small Molecules |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| , | Renamed Streamline Scientific | |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Avam | Odessa, FL | Clinical Diagnostics |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Oblenio Bio | Lexington, MA | T-cell engager antibody |
| Alibion | , | Website down May 2021 - Sep 2021 |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| Envision Pharma | , | Merged with UBC |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| Integrated Genomics | , | Changed to Igenbio |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| , | Website taken over Feb 2026 | |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| Hana Biosciences | , | Now Talon Therapeutics |
| Anavex Life Sciences | New York, NY | Small Molecules |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Website down Dec 2025 - Apr 2026 | |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| ViroMed | , | Renamed Helixmith |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| Abnovo | , | Gone |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Accumed Systems | , | Dated website, cant find any employees |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| , | Now part of Sanisure, Jun 2026 | |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Abbott | Sylmar, CA | Device Manufacturing |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Bastion Therapeutics | , | Shut down |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| DiaVax Biosciences | , | Renamed Helocyte |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| Dey LP | , | Bought by Mylan 2007 |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| , | Website down Oct 2025 - Feb 2026 | |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| 149 Medical | , | Shut down Dec 2022 |
| Saffron Therapeutics | , | Website down Oct 2021 |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| United Immunoassay | , | Business revoked Jan 2022 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| , | Renamed Algernon Health, Oct 2025 | |
| Nucleus Network | Herston, Australia | Clinical Research |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| VieVax | , | Gone Jan 2007 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Rallybio | New Haven, CT | Therapeutics |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| Amplified Proteomics | , | Shut down Jan 2006 |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| Hookipa Biotech | , | Now Hookipa Pharma |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| Cell>Point | , | Cant find any confirmation they are active |
| Cairn Research | Kent, UK | Scientific Instruments |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| , | ||
| , | Renamed Entirety Biomedical | |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Galileo Research | , | No news since 2012, presumed gone |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| , | Website down Mar 2026 - Aug 2026 | |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| AM2PAT | , | Trouble with contaminated products, gone |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| Diversa | , | Merged with Celunol to become Verenium |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Sierra Surgical | , | Shut down Feb 2019 |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Mindflow Design | , | Now part of MPE |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Gallus | , | Bought by Patheon, Aug 2014 |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Cellution Biologics | Roswell, GA | Human Placental-based Tissue Allografts |
| sRNA Dx | , | aka sRNAlytics |
| Abcam | Waltham, MA | Antibodies |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| , | Acquired by Medici Therapeutics, Nov 2025 | |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Medipacs | , | Shut down Jul 2024 |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| SWITCH Biotech | , | Gone, 2020 |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| , | Renamed Yicura, Jun 2026 | |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| , | Acquired by R-Biopharm, Jun 2022 | |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| SOCIUM | Tokyo, Japan | Contract Research |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| , | Website down Jan 2026 - May 2026 | |
| , | Merged into Meridian Bioscience | |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Novonesis | Paraná, Brazil | Enzymes |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| , | Part of Normec | |
| , | Website down Oct 2025 - Feb 2026 | |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Veramed | London, UK | Biostatistics and programming services |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Ceptyr | , | Out of business 2012 |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| ATON | Shanghai, China | CDMO |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Belmont Medical | Billerica, MA | Body Temperature Management Devices |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| Camurus | Lund, Sweden | Specialty medicines |
| CombiGene | , | Stopped research Jan 2025 |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Atherotech | , | Shut down Feb 2016 |
| ApoImmune | , | Gone 2014 |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| , | Acquired by Collate, Aug 2025 | |
| Accellacare | Knoxville, TN | Clinical Research |
| Elix | Tokyo, Japan | AI Drug Discovery |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Doer Biologics | Hangzhou, China | Biologics |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| BioDot | Irvine, CA | Equipment |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| Triangle Insights Group | Durham, NC | Consulting |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Corza Medical | Boulder, CO | Surgical Devices |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Sinotherapeutics | Shanghai, China | Generics |
| Pathens | , | Website hijacked Sep 2020 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| BioMS Medical | , | Gone? |
| , | Shut down Jun 2026 | |
| Trinity Drug Partners | , | Gone |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
|
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| BioMarin Pharmaceutical | London, UK | Biologics |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| VitaCyte | Indianapolis, IN | Collagenase |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| NanoTess | Calgary, AB | Biocatalysts |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| EVerZom | Paris, France | Exosome Therapeutics |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| DFE Pharma | Goch, Germany | Excipients |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| , | Website down Feb 2026 - Jul 2026 | |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| , | Website down Jun 2025 - Dec 2025 | |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Getinge | Solna, Sweden | Medical Technology |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Rapalogix Health | New York, NY | TORC1 inhibitors |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Viragen | , | Liquidated Oct 2007 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| TocopheRx | , | Gone before 2019 |
| PrognosDx Health | , | Website gone Jun 2016 |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| , | Website down Jun 2025 - Dec 2025 | |
| Maxivax | , | Renamed Release Therapeutics |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| Antios Therapeutics | , | Shut down Feb 2023 |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
|
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| Medallion Therapeutics | , | Shut down 2018 |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Neoneuron | San Antonio, TX | Neural Stem Cell Products for Brain Repair |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| SERB Pharmaceuticals | West Conshohocken, PA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Altiris Therapeutics | , | Presumed Gone |
|
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Medpace | Cincinnati, OH | Clinical Research |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| CATO SMS | , | Renamed Allucent, May 2022 |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| TissueNetix | , | Gone Feb 2018 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Ergomed | Belgrade, Serbia | Clinical Research |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| , | Acquired by Adial Pharmaceuticals, Jun 2026 | |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| , | Shut down Nov 2025 | |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| NeuroproteXeon | , | Gone 2021 |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Summit Therapeutics | Dublin, Ireland | Utrophin modulation technology |
| , | Website down Jan 2026 - May 2026 | |
|
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| , | Insolvent, sold off Jan 2024 | |
| Singular Genomics | San Diego, CA | Genomics |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Sysmex | Tokyo, Japan | Diagnostics |
| Amadix | Valladolid, Spain | Diagnostic development |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| Cardeas Pharma | , | Gone, 2017 |
| , | Shut down 2025 | |
| , | Website down Oct 2025 - Jan 2026 | |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| , | Bankrupt May 2025 | |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Stago | Tianjin, China | Diagnostics |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| MWG Biotech | , | Owned by Eurofins |
| Unigene Laboratories | , | Closed 2013 |
| Axya medical | , | Gone 2012 |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Cellworks | South SF, CA | Biosimulations |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Relion | , | Shut down 2015? |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Bioventus | Durham, NC | Orthobiologics |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Lupin | Somerset, NJ | Generics |
| , | Website down Dec 2025 - Apr 2026 | |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Bard1 | , | Renamed INOVIQ |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Epigenesis Pharmaceuticals | , | Gone |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| 3D Biomatrix | , | Closed down |
| Diamante | Trento, Italy | Immunotherapies Manufacured in Plants |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| icometrix | Leuven, Belgium | Imaging AI |
| Bioptimus | Paris, France | AI Drug Discovery |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| hVIVO | London, UK | Viral Services |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Endologix | Irvine, CA | Medical Devices |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| Agrisera | Vännäs, Sweden | Antibodies |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| Cam Med | , | Renamed Qlibrium |
| Onkor Pharma | , | 10 year old company with no product or website |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| Immune Technology Corp | New York, NY | Virology research products |
| , | New Apr 2023, website not ready Aug 2023 - Jun 2026 | |
| , | Acquired by IQVIA | |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Proscia | , | |
| Protein Design Labs | , | Renamed PDL Biopharma |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| Abbott | Irving, TX | Devices |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Nexgenia | , | Gone Dec 2019 |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| Mologen | , | Liquidating, May 2020 |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
|
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| Piramal | Riverview, MI | CDMO |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Flux Biosciences | , | Shut down, ~2022 |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| PreDxion Bio | , | Renamed Refractal |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| STC Biologics | Newton, MA | Services |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| Norganoid | Macclesfield, UK | Organoid Technology |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| 76Bio | , | Shut down Jan 2025 |
| NTC | Milan, Italy | Generics |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Ginkgo Bioworks | Boston, MA | Autonomous Labs |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| , | No news 2019 - Sep 2025 | |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| Revvity | Boston, MA | Diagnostics, Services |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
|
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| Tyrian Diagnostics | , | Gone 2012 |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| Mytos | London, UK | Automated Cell Culture |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| MiNA Therapeutics | London, UK | Small activating RNA |
|
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| Syneos Health | Newtown, PA | Clinical Development |
| , | No news 2021 - Sep 2025 | |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Acumed | Beijing, China | Medical Implants |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| OrphoMed | , | Shut Down 2022 |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Advanz Pharma | London, UK | Specialty Generics |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Enterin | , | Website taken over Feb 2025 |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Light Sciences Oncology | , | Shut down late 2020 |
| Whole Biome | , | Renamed Pendulum Biosciences |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Cerimon | , | Gone |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Baxter | Jayuya, PR | Medication Delivery |
| Syneos Health | Morrisville, NC | Clinical Development |
| Octapharma | Vienna, Austria | Plasma Products |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Vyteris | , | Bankrupt 2012 |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| Boehringer Ingelheim | Shanghai, China | Small Molecules, Biologics, CDMO |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Sanovel | Istanbul, Turkey | Generics |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| QT Vascular | , | Website gone Jan 2024 |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| , | Website down Jan 2026 - May 2026 | |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| NantCell | , | Renamed ImmunityBio |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| , | Website down Jun 2025 - Dec 2025 | |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| IQVIA | Durham, NC | Clinical Research |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| , | No news 2015 - Jan 2026 | |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| CrelioHealth | Columbia, MD | LIMS |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
|
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Nesher Technologies | , | Shut down Oct 2017 |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| Quartzy | Hayward, CA | Lab Management Software |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| OraPharma | , | Owned by Valeant |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Dropshot Therapeutics | , | |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| Allievex | , | Shut down Feb 2025 |
| Catamaran Bio | , | Winding down Jan 2024 |
| Avioq | Durham, NC | HIV Diagnostics |
| Promaxo | Oakland, CA | Small form MRI |
| Cyllene Therapeutics | Paris, France | Pinpoint Gene Therapy |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Lifescience Dynamics | Toronto, ON | Clinical & Commercial Strategy |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| ArKal Medical | , | Gone 2012 |
| , | Liquidating Jul 2026 | |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| Velcura Therapeutics | , | Website Gone |
| Scios | , | Bought by JnJ, Feb 2003 |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| ApniCure | , | Gone 2017 |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Orthogonal LLC | Chicago, IL | Medical device software |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| , | Renamed Cellixx, May 2026 | |
| Medtronic | Shoreview, MN | Medical Devices |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
|
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| , | No news 2021 - Apr 2026 | |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| Brightflow Medical | Paris, France | Heart Failure Device |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| BrainScope | Bethesda, MD | EEG characterization |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| NexMed | , | Now Apricus Bio |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| CBM Biopharma | , | Shut down Nov 2020 |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| EpicGenetics | , | Seems gone Jan 2024 |
| Attralus | Naples, FL | Amyloidosis Treatments |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| Horiba Instruments | Irvine, CA | Equipment |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Pathnostics | Irvine, CA | Diagnostics |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Ansaris | , | Gone |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| Promosome | , | Gone |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Hovione | Mumbai, India | Contract Manufacturing |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| OneSource Specialty Pharma | Bengaluru , India | CDMO |
| Cellipse | , | Website taken over May 2020 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Tirupati | New Delhi, India | Generics |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| , | Acquired by BICO, Aug 2021, $15M | |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| , | Website down Sep 2025 - Jan 2026 | |
| Abbott | Clonmel, Ireland | Stents |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Sampled | Motherwell, UK | Biostorage |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Pharmatrope | , | Absurd website 2020-2023 |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| Nanosonics | Hamburg, Germany | Ultrasound |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Santen | Tampere, Finland | Ophthalmics |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| , | Website down Feb 2026 - Aug 2026; Bankruptcy Jul 2025 | |
| Elektrofi | Boston, MA | Biologics Formulation |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
|
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Sepiatec | Berlin, Germany | Separation Systems |
| , | Renamed Hubot, May 2026 | |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| , | Website down Aug 2025 - Jan 2026 | |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| Korio | Doylestown, PA | RTSM Platform |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Excalipoint Therapeutics | Shanghai, China | Cell Therapy, Antibodies |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| , | Website down Jul 2025 - Dec 2025 | |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Boston Neurosciences | , | Website down Jun 2020 |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| , | Website down Oct 2025 - Feb 2026 | |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Envisagenics | New York, NY | Software-based drug discovery |
| Covaris | Woburn, MA | DNA Sample Prep |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Artimplant | , | Bankrupt, 2013 |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| Odyssey Thera | , | Shut down 2014 |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| , | Renamed Virchow | |
| Satoris | , | Bought by Rules-Based Medicine |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Constantiam Biosciences | Houston, TX | Clinical Interpretation Software |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
|
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| , | Now PamDx, May 2026 | |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Celerion | West Conshohocken, PA | Clinical Research |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| MetaMorphix | , | Changed to Scidera Genomics |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| BioConsulting International | , | Ancient website, presumed defunct |
| Tarsa Therapeutics | , | Product rights acquired |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| IQVIA | San Diego, CA | Clinical Research |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| General Oncology | Brookline, MA | Cancer Therapies |
| ImmuRx | , | Gone, not sure what happened |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| Ascelegen | , | Closed |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| Amorsa Therapeutics | , | Acquired, 2022 |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| , | Part of Evogene | |
| MSD | Brinny, Ireland | Small Molecules |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| , | Website down May 2025 - Sep 2025 | |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| EnquBio | San Diego, CA | Contract Research & Services |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Bionovica | , | Website gone Dec 2022 |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Aimmune Therapeutics | , | |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| MJ Biopharma | Mumbai, India | Generics |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Avineuro | , | Website taken over Feb 2024 |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| SuperX | , | Gone |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Acylin Therapeutics | , | Assets sold 2014 |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| Genialis | Boston, MA | Bioinformatics |
| , | Renamed Ceryvyn Therapeutics, Jul 2026 | |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Allelix | , | Merged with NPS |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Howfond | , | Website gone, Jul 2015 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Oxehealth | , | Pivoted to mental health platform |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Evofem Biosciences | San Diego, CA | Women's health |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Getinge | Mumbai, India | Medical Technology |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| Spriaso | , | No news 2019 - May 2025 |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| , | Website down Mar 2026 - Aug 2026 | |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Ximedica | San Francisco, CA | Medical Device Services |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Hansa Medical | , | Renamed Hansa Biopharma |
| Pathfinder Cell Therapy | , | Gone 2016 |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| Station X | , | Website Gone Mar 2018 |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| SDIX | Newark, DE | Diagnostics |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Epigen | , | Renamed Egenix, 2002 |
| Tactic Pharma | , | Website gone, Apr 2018 |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| , | No news 2020 - Apr 2026 | |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Jet Life Sciences | Hyderabad, India | APIs |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| , | Shut down Jan 2024 | |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| Surface Logix | , | Bought by Nano Terra |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Parabase Genomics | , | Presumed gone |
| Sharp | Conshohocken, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
|
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| Crown Bioscience | Beijing, China | Drug Development |
| Vodori | Chicago, IL | Commercial Content Software |
| Trident Lifeline | Surat, India | Generics |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
|
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| CombImmune | , | Website Gone Jul 2015 |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| Syndax Pharmaceuticals | New York, NY | Tumor Phenotype Modification |
| CellASIC | , | Bought by Millipore, May 2012 |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| LipimetiX Development | , | Website gone, Jan 2020 |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Root Lines Technology | , | Renamed Samabriva |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Apgene Bio | , | Shut down Oct 2020 |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Teva | Toronto, ON | Small Molecules |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Sinovac Biotech | Beijing, China | Vaccines |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| Novotech | Bangalore, India | Clinical Research |
| , | Website down Jan 2026 - Mar 2026 | |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Flow Eighteen38 | , | |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| , | No news 2017 - Apr 2026 | |
| Innovagen | Lund, Sweden | Custom antibody development |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Ally Therapeutics | , | Shut down early 2021 |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| , | Website down May 2025 - Dec 2025 | |
| Anatomise Biostats | London, UK | Biostatistics |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| AcroCyte Therapeutics | New Taipei, Taiwan | Scaffold-free 3D Cell Culture |
|
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| Pharmaron | Northamptonshire, UK | R&D Services |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| MitoStem | , | Seems gone |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| BionX Medical | , | Acquired by Ottobock |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Rho | Durham, NC | Clinical Research |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Heart Repair Technologies | , | |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| MEDISPECTRA | , | Gone 2002 |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| Transmed Oncology | , | Gone? |
| LexaMed | Toledo, OH | Life Science Consulting |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| , | Website down Sep 2025 - Feb 2026 | |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Getinge | Orléans, France | Medical Technology |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| AxioMed | , | President left in 2018, not registered in MA |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Nido Surgical | , | Shut down Apr 2022 |
| , | Website down Feb 2026 - Aug 2026 | |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| CoAxia | , | Closed down Spring 2013 |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Bhami's Research Laboratory | Mangaluru, India | Monoclonal Antibody Excipients |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Gen Plus | Munich, Germany | Formulation |
| VERAXA Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| VytronUS | , | Shut down Mar 2020 |
| Hydra Biosciences | , | Website gone Mar 2019 |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| Kurin | San Diego, CA | Blood Collection Technology |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| , | Website down Sep 2025 - Feb 2026 | |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Cirina | , | Merged with Grail, May 2017 |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| Curry Pharmaceuticals | , | Closed 2008 |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| GenoImmune | , | |
| Karykion | , | Website outdated, doesn't seem serious |
| Macusight | , | Effectively acquired by Santen, 2008 |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| , | Inactive May 2025 | |
| Qbiogene | , | No website. Fisher sells their products |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Medley Genomics | , | Website for sale Feb 2021 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| Xenikos | , | Shut down early 2023 |
| SironRx | , | Website gone Jul 2015 |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| , | Shut down Feb 2026 | |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Silence Therapeutics | London, UK | RNAi |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| ADispell | , | Website gone Apr 2018 |
| Certego Therapeutics | , | Seems gone May 2023 |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| Meditrial | New York, NY | Clinical Services, Software |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Locanabio | , | Shutting down late 2023 |
| , | Renamed Silthera, Apr 2026 | |
| , | Renamed WallabyPhenox | |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Allsino Pharmaceutical | Hangzhou, China | Synthetic Pharma Manufacturing |
| iBio | San Diego, CA | Antibody Therapies |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Vernacare | Bolton, UK | Surgical Devices |
| Akubio | , | Bankrupt Sep 2007 |
| , | Acquired by Instem, Jul 2025 | |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| Divergence | , | Bought by Monsanto |
| BioTeam | Middleton, MA | Scientific IT consulting |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| , | No news 2019 - Jul 2026 | |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
|
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Wiener lab | Capital Federal, Argentina | Reagents, Instruments, Software |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| RecoRNA | Guangzhou, China | RNA-based Precision Medicine |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Abbott | Altavista, VA | Nutrition |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Amstem | , | SEC problems |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| Securecell | Urdorf, Switzerland | Lab automation |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| VM Discovery | , | 20 yr old company with no info on website |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| StemCell2MAX | , | Website gone Apr 2019 |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| SunMed | , | Renamed AirLife |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Saghmos Therapeutics | , | |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Novotech | Taipei, Taiwan | Clinical Research |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Davol | , | Acquired by Bard, 1980 |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Tecomet | Bridgeport, MI | CNC Machining, Cutting Instruments, Orthopedics |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| Topivert | , | Liquidating Jan 2021 |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Orion Genomics | St. Louis, MO | Biomarkers |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| PDL BioPharma | , | Shut down early 2021 |
| Actylis | Port Washington, NY | Raw Materials |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| Nanoferix | , | Renamed Pendant Biosciences |
|
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Z-Factor | , | Centessa Company |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| QuantRx Biomedical | , | Shell company |
| BioGaia | Stockholm, Sweden | Probiotics |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| Denk Pharma | Munich, Germany | Generics |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Masy Systems | , | fka Masy Biosystems |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| Omnimmune | , | Shell company, trademark abandoned |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Kallyope | New York, NY | Gut-brain axis focus |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Marical | , | Website Gone |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Tecomet | Cork, Ireland | CNC Machining, Finishing, Inspection, Plastics Machining, Shotpeening |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| AB Science | Paris, France | Small Molecules |
| Lombard Medical | Didcot, UK | Medical Devices |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
|
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| GlycoSolutions | , | Closed Aug 2015 |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Formulatrix | Bedford, MA | Lab Automation |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| DP Clinical | Rockville, MD | Clinical Research |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| Pulse Biomedical | , | Distributor |
| AdvaStim | , | Shut down, Dec 2017 |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| UVision 360 | , | Renamed Luminelle |
| , | Acquired by Affluent Medical, Feb 2026 | |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| icometrix | Boston, MA | Imaging AI |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| , | Website down Feb 2026 - Jul 2026; aka Integrity Implants | |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| Spiriplex | , | Bankrupt, Mar 2023 |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| Kivu Bioscience | San Francisco, CA | ADCs |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
|
Göttingen, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
|
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| , | Renamed Trace Biosciences | |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| CSL Behring | Bradley, IL | Biologics |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Vega Therapeutics | , | Acquired by Incyte, Jul 2026, $1.25B; Part of Star Therapeutics |
| OccuRx | , | Merged into Certa Therapeutics |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| Valerio Therapeutics | Villejuif, France | Orphan Diseases, Decoy Oligonucleotides |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Commence Bio | , | Gone 2018 |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| TTP Labtech | , | Renamed SPT Labtech |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| Theravance Biopharma | South SF, CA | Small Molecules |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Mederi Therapeutics | , | Now Mederi-RF |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Balboa Biosciences | , | Gone 2010 |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Allenex | , | Bought by CareDx, Apri 2016 |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| HEC | , | Website down Dec 2024 - May 2025 |
| Human Genome Sciences | , | Bought by GSK |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Mithridion | , | Website Gone, Company appears to be as well |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| , | Website down Oct 2025 - Feb 2026 | |
| , | Website down May 2025 - Dec 2025 | |
| genOway | Lyon, France | Rat and cell models |
| Interdict | San Francisco, CA | Small Molecules |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| XenaCare | , | Gone |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| , | Acquired by InformedDNA, Mar 2025 | |
| RNA Therapeutics | , | No website Mar 2020 |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Gencove | Long Island, NY | Genome Sequencing |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| Elan | , | Bought by Perrigo, Dec 2013 |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| YMC Process Technologies | Devens, MA | Purification Technology |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation pseudo-subsidiary | |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| StaphOff Biotech | , | Shut down 2017 |
| Epigene Labs | Paris, France | Data Integration Platform |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Smithers | Akron, OH | Contract Research |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Alaeras | , | Dissolved Jan 2014 |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Accellacare | Bristol, TN | Clinical Research |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| Organogenesis | Canton, MA | Biologics |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| Medtronic | Jacksonville, FL | Medical Devices |
| VGX Pharmaceuticals | , | Merged with Inovio |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Tarpon Biosystems | , | Gone by 2017 |
| , | Acquired by Syner-G BioPharma Group | |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| Brilliant Research | , | Website gone Dec 2018 |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Avrygen | , | Website Gone, execs gone |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| , | Renamed Turing Medical | |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| AccelaPure | , | Bankrupt 2007 |
| Unither Pharmaceuticals | Paris, France | CDMO |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| GSK | Hamilton, MT | Vaccine additive |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| , | Acquired by Bora CDMO, Oct 2022 | |
| CombinatoRx | , | Now Zalicus |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| Eleven P15 | , | Shut down |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
|
Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| , | Winding down Jan 2026 | |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| PharmacoFore | , | Now Signature Therapeutics |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Theracos | , | Renamed TheracosBio |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Tethys Bioscience | , | Shut Down, late 2013 |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| StemBioSys | San Antonio, TX | Stem Cells |
| , | Renamed MindWalk, Sep 2025 | |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| LifeMax | , | Part of AmMax |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| , | Acquired by Sanofi, Jul 2025, $9.1B | |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Amoytop Biotech | Xiamen, China | Biologics |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| , | Renamed Arpelos Biosciences | |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Shionogi | Florham Park, NJ | Small Molecules |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| , | ||
|
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| Wheaton | , | Renamed DWK Life Sciences |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| , | No news Aug 2019 - Jan 2026 | |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Delpor | Brisbane, CA | Drug Delivery System |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| LunaDNA | , | Shutting down Jan 2024 |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| , | Website down Feb 2026 - Jul 2026 | |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Sinobioway | , | |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| Aspira Labs | , | Renamed Aspira Women's Health |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| Cardima | , | Bankrupt Dec 2010 |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Tides Medical | Lafayette, LA | Biologics |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| , | Website down Jan 2026 - May 2026 | |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Optime Therapeutics | , | Acquired by Lippomix |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
|
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Steris | Mentor, OH | Contamination Control |
| NinePoint Medical | , | Seems gone Sep 2020 |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Protox Therapeutics | , | Now Sophiris Bio |
|
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Infinitopes | Oxford, UK | Vaccines |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Getinge | Fairfield , NJ | Medical Technology |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Halloran Consulting Group | Boston, MA | Consulting |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Gene Sciences | , | Shut Down Jul 2019 |
| , | Acquired by Vaxanix, May 2024 | |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| AstronauTx | London, UK | Alzheimer's Treatments |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| SegAna | , | Website down May 2021 - Sep 2021 |
| SoBran | Falls Church, VA | Preclinical Services |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Patronus Biotech | Singapore, | |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| , | Renamed Helus Pharma, Jan 2026 | |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| Amivas | Waterford, Ireland | Antimalarial |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Sania Therapeutics | London, UK | CNS Treatments |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| ProUroCare Medical | , | Gone |
| SERB Pharmaceuticals | Luxembourg, Luxembourg | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| , | Website taken over May 2026 | |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| AN2 Therapeutics | Menlo Park, CA | Boron-based medicines targeting infectious diseases |
| , | Website down Jan 2026 - May 2026 | |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| , | Website down Dec 2025 - Apr 2026 | |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| SemBioSys | , | Bankrupt, Jul 2012 |
| , | Acquired by EPI, Mar 2022 | |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Kinaxo | , | Bought by Evotec |
| Integer | Plano, TX | Medical & Surgical Devices |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Insulete | , | Website gone, presumed inactive |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Gangagen | Bangalore , India | Ectolysins |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Chroma Medicine | , | |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
|
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Genfit | Cambridge, MA | Drug Discovery |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| BalinBac Therapeutics | , | Gone 2018 |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| , | Renamed Cyllene Therapeutics, Jul 2026 | |
| Nanobiotix | Paris, France | Nanoparticles |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Silere Medical Technology | , | Shut down Dec 2013 |
| EndoStim | , | Shut down Jan 2020 |
| Tequesta BioScience | , | Defunct |
| Gennova Bio | Pune, India | mRNA vaccine |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| Genae Associates | , | Acquired by IQVIA |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| Ufovax | , | Renamed Uvax Bio? |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Carolus Therapeutics | , | Business revoked in CA |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| , | Acquired by bioMerieux, Sep 2013, $450M + debt | |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Amachumu Bio | , | Shut down April 2021 |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| MantaBio | Beverly, MA | Real-time PCR System |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Restek | Bellefonte, PA | LCGC Equipment |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| ImmuneXcite | , | Closed Oct 2017 |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| , | Renamed Racura Oncology, Dec 2025 | |
| Epygen Biotech | Arvada, CO | Biosimilars |
| CureBiotech | , | Presumed gone |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Neuraxpharm | Langenfeld, Germany | Generics |
| , | ||
| Genalyte | San Diego, CA | Multiplexing Instruments |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Active Pass Pharmaceuticals | , | Gone |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| , | No news 2019 - Sep 2025 | |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| , | Shut Down Dec 2024 | |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| BioSpherex | , | Renamed Metabiomics |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Loop Therapeutics | , | Shut down Jan 2021 |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| Sharp | Bethlehem, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
|
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| , | Website down Aug 2025 - Jan 2026 | |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| AstraZeneca | Boston, MA | Biologics |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Alvea | , | Shut down Oct 2023 |
| Ciphergen | , | Now Vermillion |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| , | Shut down June 2024 | |
| , | Website down Aug 2026; LI gone Jul 2026; Co-work space/Residential Address, Sep 2022 | |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| , | Acquired by CorMedix, Sep 2025, $300M; Filed bankruptcy Dec 2019, acquired out of bankruptcy outright by Deerfield Mar 2020; fka Rib-x | |
| Vaxart | South SF, CA | Oral Vaccines |
| ZyGEM | , | Renamed MicroGEM |
| Point Biomedical | , | Liquidated Jul 2008 |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Piramal | Ennore, India | CDMO |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| AccuVein | Medford, NY | Vein Visualization |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| Getinge | Ankara, Turkey | Medical Technology |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Getinge | Delft, Netherlands | Medical Technology |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Altan Pharma | , | Acquired by Ethypharm |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| NeoVentures | London, ON | Custom Aptamers |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Nizyme | , | Gone Jul 2015 |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| Entropia Biosciences | , | Shut Down June 2019 |
| Cymbiotics | , | Gone 2019-2020 |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| CertiRx | , | Shut down |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| RheoSense | San Ramon, CA | Viscometers |
| Penwest | , | Bought by Endo |
| LyoGo | , | Website gone, all employees gone |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
|
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Website down Jul 2025 - Dec 2025 | |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| Sunho Biologics | Nanjing, China | Biologics |
| Hua Medicine | Shanghai, China | Small Molecules |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| Vernacare | Blackwood, UK | Surgical Devices |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| , | No news 2021 - Sep 2025 | |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Spear Bio | Woburn, MA | Immunoassays |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Vericel | Cambridge, MA | Cellular Therapy |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| , | Renamed Ladder Bio, Nov 2025 | |
| BioDevek | , | Formerly LabCentral, seems gone |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| SFS | Madrid, Spain | Clinical Research Organization |
| , | Website down Oct 2025 - Feb 2026 | |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
|
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Ascenta Therapeutics | , | Gone |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| Obenomics | , | No website Apr 2014 |
| Vedere Bio II | , | Shut down Mar 2023 |
| Ambion | , | Bought by Applied Biosystems 2006 |
| GenoSpace | Boston, MA | Platform for genomic data |
| Nura | , | Acquired by Omeros |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| BioFluentLabs | , | Shut down July 2012 |
| , | Filings late Mar 2025 - Feb 2026 | |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Accutome | , | Now part of Keeler |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| , | Outlicensed sole product Sep 2021 | |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| Menarini | Firenze, Italy | Small Molecules |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Zai Lab | Shanghai, China | Small Molecules |
| Omnia Biologics | , | Website gone Sep 2017 |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Chanelle Pharma | London, UK | Generics |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Clinnex | Ahmedabad, India | Clinical Research |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| Avontec | , | Gone |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| Catalina Pharma | , | No info 2017-2022 |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| , | ||
| Suir Pharma | , | Bankrupt, May 2016 |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Medtronic | Cincinnati, OH | Medical Devices |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Cellnovo | , | Bankrupt, Jul 2019 |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| , | Website down Aug 2025 - Jan 2026 | |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| NeuroVista | , | Website Gone, President has new job |
| Evvy | New York, NY | At-home vaginal microbiome test |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| Cherry Biotech | Paris, France | Organoid Culture |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| , | Shut down Dec 2023 | |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| , | Website down Oct 2025 - Jan 2026 | |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
|
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Panacos | , | Believe they are inactive |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| , | Renamed Until Labs, Oct 2025 | |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| Anumana | Cambridge, MA | AI ECG reading |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Meabco | , | |
| NextPharma | Limay, France | Contract Research & Development |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| nference | Cambridge, MA | Clinical AI |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| , | Acquired by HB Fuller, Jul 2023 | |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| ABgene | , | Bought by Apogent, Dec 2001 |
| Univfy | Los Altos, CA | IVF reports |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| TheraCoat | , | Renamed UroGen Pharma |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| , | Acquired by IQVIA | |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Cdymax | Bangalore, India | APIs |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| EhmetDx | , | Renamed Ehmet Health |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| , | No news 2021 - Jan 2026 | |
| Astek Diagnostics | Baltimore, MD | UTI Diagnostic |
| Faze Medicines | , | Shutting down Nov 2022 |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Cytomatrix | , | Gone, Jun 2013 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| METiS Technologies | , | |
| Znomics | , | Bankrupt, Shell Company Now |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Sanofi | Reading, UK | Small Molecules |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| Microsize | Quakertown, PA | Microionization CDMO |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Symansis | Timaru, New Zealand | Reagents |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Piramal | Digwal, India | CDMO |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Immunogen (1) | , | Renamed ImmunogenX |
| , | No news 2022 - Mar 2026 | |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| InCytu | , | Website gone Jul 2015 |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Salus Bioscience | , | Forfeited in CA |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Formycon | Martinsried, Germany | Biosimilars |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| ParinGenix | , | Gone, 2012? |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| , | Website hijacked, LI gone Jul 2026 | |
| Tulyp Medical | , | Pressure-driven perfusion system |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Abbott | Longford, Ireland | Diagnostics |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| Attogene | Austin, TX | Rapid Diagnostics |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Zomanex | , | Gone Oct 2019 |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| KynderMed | , | Renamed Prena |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| , | Renamed Revr Jan 2026 | |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| Cell Biosciences | , | Now ProteinSimple |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| MYcroarray | , | Renamed Arbor Biosciences |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| Endothelix | , | Now owned by American Heart technologies |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| , | Renamed Torpedo Therapeutics | |
| CytoMol (2) | , | SF-based, Looks gone |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| Avistone | Beijing, China | Precision Oncology |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Kate Therapeutics | , | |
| Cellevolve Bio | , | Shut down Aug 2023 |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Niowave | Lansing, MI | Radioisotopes |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| Cadex Genomics | , | Shut down Jul 2024 |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Marpē Therapeutics | , | Professor sideline |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| , | Website down Jul 2026; Linkedin gone Jul 2026; Filings late Aug 2025; fka AilseVax | |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| ProteinLinks | , | Seem gone |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Jerini | , | Acquired by Shire, 2008 |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| BostonGene | Waltham, MA | Biomedical Software |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Novaliq | Cambridge, MA | Drug Delivery |
| , | Became part of Accelerator, Dec 2025 | |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
|
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Ventaleon | , | Shut down 2020 |
| Harmony Labs | , | Now Ei |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| , | No news 2021 - Jun 2026 | |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Roowin | Riom, France | Chemical Synthesis |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
|
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Radical Numerics | San Francisco, CA | Generative genomics |
|
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Limerick Bio | , | Gone 2011 |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| Tecomet | Oregon City, OR | Casting, Bone In-Growth Coating |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| Biorelate | Manchester, UK | AI Data Curation |
| Synedgen | Claremont, CA | Biofilm Control |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Avecris | Singapore, Singapore | Gene Delivery |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| Nanometrix | London, UK | Nanoscale Data on Extracellular Vesicles |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Tecnimede | Lisbon, Portugal | Generics |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| Yung Shin Pharm | Taichung, Taiwan | Small Molecules, Generics |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| , | Website taken over Feb 2026 | |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| , | Acquired by Altaris, Mar 2025 | |
| BA Sciences | Morrisville, NC | Analytical Services |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| Anchen | , | Bought by Par Pharmaceutical |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| MedCision | , | Assets bought by MedCision, May 2018 |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| , | Renamed Mighty Therapeutics, Jun 2026 | |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
|
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| West-Ward | , | Now part of Hikma |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| Olon USA | Concord, OH | Contract Research |
|
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| Sicor Biotech | , | Bought by Teva 2004 |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Akkadix | , | Gone 2001 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| bioRASI | Aventura, FL | Clinical Research |
| CNCure | Jeollanam, Korea | Tumor-targeting Bacteria |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| Tikva Allocell | Proteos, Singapore | Cancer and autoimmune therapies |
| AlloCure | , | Website Gone, Jul 2015 |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Bayer | Bitterfeld, Germany | Small Molecules |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| AGI Therapeutics | , | Bought by Videra |
| Madison Vaccines | , | Website gone Dec 2019 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| Genedata | Basel, Switzerland | Bioinformatics |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| mAbRx | , | Gone |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| TcLand Expression | , | Website Gone |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| , | Website down Jan 2026 - May 2026 | |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| , | Website down Apr 2026 - Jul 2026, LI gone Jul 2026 | |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| , | No news 2019 - Aug 2026 | |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Novelty Nobility | Seongnam, Korea | ADCs |
| NantHealth | El Segundo, CA | Diagnostics |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| Ezose Sciences | , | Rebranded as S-bio |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| , | Website down Jun 2025 - Dec 2025 | |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Altasciences | Montréal, QC | Contract Research |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| Velos | , | Acquired by WCG, Mar 2018 |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| Instylla | Bedford, MA | Embolization treatment |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| , | Acquired by Axora Medical, Jan 2026 | |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| AAVLife | , | Renamed Annapurna |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| Turku Bioscience | Turku, Finland | Research Services |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Tella | , | Website down May 2023 - Dec 2023 |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Align Technology | Tempe, AZ | Teeth alignment |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| ChemRegen | , | Seems gone Jan 2022 |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
|
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Bayer | Bergkamen, Germany | Small Molecules |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| V-gene | , | Website gone, Aug 2017 |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| AFID Therapeutics | , | Gone 2012 |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Hovione | Macau, China | Contract Manufacturing |
| Ikano Therapeutics | , | Gone |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Celavie Biosciences | , | Shut down Mar 2024 |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Genmab | Plainsboro, NJ | Biologics |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| Coral Drugs | New Delhi, India | APIs |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| , | No news 2021 - Jul 2026 | |
| BeOne Medicines | Pennington, NJ | Small Molecules, Monoclonal Antibodies |
| RS Medical | Vancouver, WA | Medical Devices |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| , | Renamed Edding, Feb 2026 | |
| Oncology Clinical Research | , | Gone |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Vernacare | Newtown, UK | Surgical Devices |
| Qualicaps | Whitsett, NC | Capsules |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| MicroPort | Saluggia, Italy | Medical Devices |
|
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| , | Crypto Pivot, Nov 2025 | |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
|
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| InxMed | Beijing, China | Oncology Treatments |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Ativa Medical | , | Renamed Immune IQ? |
| Hemab Therapeutics | Frederiksberg, Denmark | Bleeding Disorder Treatments |
| BINEX | Incheon, Korea | Biologics CDMO |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| Altasciences | Cypress, CA | Contract Research |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Revance | Nashville, TN | Movement Disorder Treatment |
| , | Website down Sep 2025 - Dec 2025 | |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| Pharmathen | Marousi, Greece | Generics |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Fusion Biopharma | , | Presumed gone |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Santen | Osaka, Japan | Ophthalmics |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Ziphius Vaccines | Zwijnaarde, Belgium | Self-amplifying RNA Vaccine |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| 1859, Inc. | , | Shut down Jul 2023 |
| Maplehurst Genetics International | , | Website gone |
|
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Solace Pharmaceuticals | , | Out of business 2011 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| Avecia | , | Bought by Nitto Denko |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Ergomed | Madrid, Spain | Clinical Research |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| ChunLab | , | Renamed CJ Bioscience |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| , | No news 2017 - Apr 2026 | |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Mediso | Budapest, Hungary | Medical Imaging |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| CGT Global | Folsom, CA | Tissue Sourcing |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| BioCrea | , | Website Gone, Feb 2018 |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| Silktap | , | Liquid silk. Site gone |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| August Therapeutics | , | Shut down Dec 2024 |
| Curis | Lexington, MA | Small Molecules |
| Annova Chem | , | Gone, 2017 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
|
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| De Novo Pharmaceuticals | , | Gone, unknown |
| , | Renamed Verge Labs, May 2026 | |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Zensun | , | Website gone Jan 2019, Chinese company |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| Iquity Labs | , | Merged into Decode Health |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| IMS Health | , | Merged with Quintiles, May 2016 |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| JABio | , | Shut Down May 2021 |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| , | Acquired by Tarsus Pharmaceuticals, Jul 2026, $75M + $490M milestones | |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| Scion NeuroStim | , | Presumed gone |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| MSD | Dublin, Ireland | Women's Health Products |
| NeuClone | Sydney, Australia | Biosimilars |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Tecomet | Riviera Beach, FL | CNC Machining, EDM, Special Processes |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| ViroPharma | , | Bought by Shire Jan 2014 |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| , | Dissolved, Apr 2024 | |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| Sharp | Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Animas | , | Shut down, Oct 2017 |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| DKP Genomics | , | Dissolved Jul 2025 |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| , | Website down Feb 2026 - Jul 2026 | |
| SNBL | , | Acquired by Altasciences |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| , | Website down Feb 2026 - Aug 2026 | |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| NNS Clinical Research | , | Gone |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| Existence Genetics | , | Bankrupt Dec 2012 |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| CoreMap | Burlington, MA | High-resolution cardiac electrophysiology mapping system |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| New Brunswick Scientific | , | Merged into Eppendorf |
| Proteorex | , | Gone Nov 2017 |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| , | Shut down Feb 2026 | |
| Gentian USA | Moss, Norway | IVD Products |
| EndoLogic | , | Seems inactive, Aug 2023 |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| ConjuChem | , | Bankrupt 2011 |
| Western Biologics | , | Dissolved, 1998 |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Arcadia Science | Emeryville, CA | Evolution-based Drug Discovery Model |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| , | Website down Jul 2025 - Dec 2025 | |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| , | Website down Feb 2026 - Jul 2026 | |
| Vanquish Oncology | , | No news 2015-2021 |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Vision Medicines | , | Gone 2017 |
| , | Shut down late 2025 | |
| Advancells | Noida, India | Stem Cell Treatments |
| ImmuneMed | , | Shut Down |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Rox Medical | , | Gone 2019 |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
|
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
|
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| , | Website down Mar 2026 - Aug 2026 | |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Wepredic | Saint Gregorie, France | Cell Lines |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Hemadvance | , | Gone |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| SelectX | , | Website hacked; No updates since 2011 |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| CYTOO Cell Architects | , | |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Cellex | , | Presumed Gone |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| Terumo Medical | Somerset, NJ | Medical Devices |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Vaccibody | , | Renamed Nykode Therapeutics |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| OptiVia Medical | , | Website looks pretty terrible |
| , | Renamed PsiThera, Dec 2025 | |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| NX Development | Lexington, KY | Brain Imaging |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| , | CEO, Li gone Aug 2026 | |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| British Biotech | , | Merged into Vernalis 2003 |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| PRACS Institute | , | Bankrupt 2013 |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| , | No news Nov 2021 - Jul 2026 | |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Zila | , | Bought by Tolmar, Jul 2009 |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| XDx | , | Changed name to CareDx |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Opsonix | , | Shut down May 2018 |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Baxter | Marion, NC | Medication Delivery |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| , | Acquired by Again, Aug 2026 | |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| , | Website down Dec 2025 - Apr 2026 | |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| , | Acquired by MasterControl, Mar 2025 | |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Picoseq | , | Renamed Depixus |
| , | Website down May 2025 - Dec 2025 | |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| MDQuest | , | Website Down Feb 2025 |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| Kendle | , | Acquired by INC Research 2011 |
| , | No info 2019 - Mar 2026 | |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| Apobiologix | Toronto, ON | Biosimilars |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Gran Med | , | Gone |
| , | Acquired by Repligen, Sep 2021, $150M | |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| , | Renamed Precursion Biosciences, Jun 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Curium | , | Dissolved, Mar 2015 |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Bayer | Berlin, Germany | Small Molecules |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| , | No news 2019 - Jan 2026 | |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| , | Website down Jul 2025 - Dec 2025 | |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| , | Acquired by Uniphar | |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| Oligasis | , | Changed named to Kodiak Sciences |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| , | Website down Feb 2025 - Dec 2025 | |
| Berg | , | Acquired, Jan 2023 |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Roche | Mannheim, Germany | Diagnostics |
| , | Website down May 2025 - Dec 2025 | |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
|
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Collate Software | San Francisco, CA | Paperwork Streamlining |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Mousera | , | Renamed Vium |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Angel Biotechnology | , | Bankrupt, 2013 |
| Tecomet | Memphis, TN | Bone In-Growth Coating |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| Almac | Craigavon, UK | Pharmaceutical Services |
| , | Website down Jul 2025 - Jan 2026 | |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| , | Website taken over, Nov 2025 | |
| Cunde Medical | , | mRNA Cell Therapy combo |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| Broken String Biosciences | England, UK | Gene Edited Cell & Gene Therapy |
| Riboxx | Dresden, Germany | RNA Products |
| Vanadis Laboratories | , | Gone 2018 |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Mastel Surgical | Rapid City, SD | Surgical Devices |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| , | Acquired by HiRO, Aug 2023 | |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| Biocious Life Sciences | , | Now Agilent |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Cytera CellWorks | , | Renamed Mytos |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| Polytherapeutics | , | Gone Jun 2018 |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Nanosonics | Manchester, UK | Ultrasound |
| Launchpad Therapeutics | , | |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Miami Cardiovascular Innovations | , | Gone Sep 2009 |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| PharmaVigilant | , | Gone 2014 |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| , | Abbott alums in Sioux Falls, ID, none on Linkedin Mar 2025 | |
| Anthra Pharmaceutical | , | Gone |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| NIOX | Morrisville, NC | Asthma management device |
| OverT Bio | New York, NY | Cell Therapy |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| , | No news 2019 - Jul 2026; Residential Address, Mar 2020 - Sep 2024 | |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Hemaquest | , | Gone by 2017, No info |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| VictoGen | Simi Valley, CA | Analytical, Formulation Development, Regulatory |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Abbott | Princeton, NJ | Diagnostics |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| , | Merged with Vaxanix | |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Biosion | Nanjing, China | Bispecific Antibody |
| , | Acquired by MMS, Feb 2025 | |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Accellacare | Ames, IA | Clinical Research |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Mentrik Biotech | , | Gone |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Qurasense | , | Renamed Qvin |
| Heraeus Medical | Changshu, China | Medical Devices |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Celerion | Belfast, UK | Clinical Research |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Getinge | Suzhou, China | Medical Technology |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| , | Website down Nov 2025 - Apr 2026 | |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| PharmaGap | , | Shut down 2013 |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| Novoresearch | , | Gone 2014 |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| American Biooptics | , | Renamed Avivo BioOptics |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| , | ||
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| Huons | Seongnam, Korea | Small Molecules |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| OpenClinica | Needham, MA | Clinical Study Software |
| Novocell | , | Renamed Viacyte |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| BinaryBio | , | Out of business Jul 2015 |
| Abselion | Cambridge, MA | Biologics Quantification |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| Proteom | , | Acquired by Amura Ltd |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Eminent Services | Frederick, MD | Drug Services |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| , | Website down Apr 2026 - Jul 2026, LI gone Jul 2026 | |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| , | Renamed Cordica Medical, Jan 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Calixar | Lyon, France | Membrane Proteins |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| InnoCare | Shanghai, China | Cancer Treatments |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| GeneVivo | , | Unknown Fate |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| , | Website down Jul 2025 - Dec 2025 | |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Balance Therapeutics | , | Gone late 2020 |
| MeiraGTx | London, UK | Gene Therapy |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
|
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| KVK Tech | Newtown, PA | Generics |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Cordis | Miami Lakes, FL | Medical Devices |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Cilag | , | Joined J&J 1959 |
| , | Website down Dec 2025 - Apr 2026 | |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Genometry | , | Shut down Dec 2019 |
| Amrita Therapeutics | , | Seems gone |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Gerostate Alpha | , | Shut down Dec 2024 |
| Ximedica | Plymouth, MN | Medical Device Services |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| Pangea Pharmaceuticals | Brielle, NJ | Generics, B2 |
| Axplora | Mourenx, France | API manufacturing |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Neuromatters | , | Shut down Dec 2019 |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Talee Bio | , | Renamed Spirovant Sciences |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Centinel Spine | West Chester, PA | Spinal Implants |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| Lab901 | , | Bought by Agilent |
| Formation Bio | New York, NY | AI Drug Discovery |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Niramai | London, UK | AI-breast cancer detection device |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Oncovista | , | Dormant 2016 |
| Quentis Therapeutics | , | Shut down late 2020 |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| , | Website down Jul 2025 - Jan 2026 | |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| Omneuron | , | Closed |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| Sanofi | Haverhill, UK | Small Molecules |
| Adela | Toronto, ON | Liquid Biopsy |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Quantamerix | , | No info since 2012, never registered in MA |
| Nuvelution Pharma | , | Gone 2020 |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
|
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Piramal | Hyderabad, India | CDMO |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| Peptone | London, UK | Translational Biophysics |
| Gene Express Inc | , | bankrupt? |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Domainex | Essex, UK | Drug Discovery Services |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| , | Acquired by Avania, Oct 2024 | |
| Core Dynamics | , | Gone |
| SRI International | Menlo Park, CA | Independent Research |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| , | No news 2021 - Jun 2026 | |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
|
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Qool Therapeutics | , | Gone Jan 2021 |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| ROKIT | Seoul, Korea | Organ Regeneration |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Soletics | , | Website gone Jun 2021 |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| VasculoMedics | , | Gone 2019 |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
|
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Magnendo | Newton, MA | Neurovascular Access with Robotic Navigation |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Pharmaron | Beijing, China | R&D Services |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Texcell | Gronau, Germany | Contract Research |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Allogene Therapeutics | South SF, CA | CAR-T |
|
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| , | Website down Feb 2026 - Jul 2026 | |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| Neurogene | New York, NY | Genetic Therapies |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| , | Seems unserious, Jul 2026; fka Cetazam Therapeutics | |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Genexa | , | Shut down before Nov 2023 |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
|
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Zuma Biosciences | , | Company Gone |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Orros Therapeutics | , | gone 2018 |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| QuiO Technologies | , | CEO Founder gone late 2021 |
|
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Advantagene | , | Renamed Candel Therapeutics |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| , | Website down Dec 2025 - Apr 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Verséa Health | Tampa, FL | Diagnostics |
| Virapur | , | Acquired by Microbiologics, 2017 |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Instil Bio | Dallas, TX | Cell Therapy |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| MeiRui Pharma | , | Bought by GSK |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Occam Design | Louisville, SS | Medical Device Development |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Nexus Spine | Salt Lake City, UT | Spinal Implants |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| Biotest Labs | , | Acquired by/Merged with Steris |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| Biowarn | , | Gone |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| bioMerieux | Cambridge, MA | Diagnostics |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Apollo Scientific | Manchester, UK | Research Products |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Affinity Bio | , | Renamed MyriO Tx |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Scilucent | Fairfax, VA | Regulatory Consulting |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Viva Biotech | Jiaxing , China | Contract Research |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| AmplifyBio | , | Shut down Apr 2025 |
| , | Website down Feb 2026 - Aug 2026 | |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| , | Acquired by GeneDx, May 2025, $33M + $18M Milestones | |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Moleac | Singapore, Singapore | Stroke Products |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| Innexus Biotechnology | , | Gone |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| , | Website down Oct 2025 - Feb 2026 | |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| Ymir Genomics | , | Dissolved Jun 2021 |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Genetic Technologies Group | , | Renamed geneType |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| Norgine | Madrid, Spain | Specialty Pharma |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| ApoVax | , | Shut down Jul 2014 |
| Optovue | , | Renamed Visionix Sep 2021 |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
|
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Oncodesign Services | Dijon, France | Preclinical services |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| ViThera Pharmaceuticals | , | Gone 2017 |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| Medicure | Holetown, Barbados | Small Molecule |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| Altasciences | Scott Township, PA | Contract Research |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Invenio Imaging | San Jose, CA | Histology, Cavity Sampling |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| Revolution Biomanufacturing | Worcester, MA | mRNA, lipid nanoparticle CDMO |
| Phytomedics | , | Can't find info on it |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| Abbott | Donegal, Ireland | Diagnostics |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| Esculon | , | Seems defunct, employees gone |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| LinaTech | Suzhou, China | Cancer treatment device |
| NextGen Sciences | , | Defaulted, sued by employees |
| Biolab | Mississauga, ON | Small Molecules |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Cognosetta | , | Gone 2021 |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| DelSite | , | Bankrupt |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| , | Website down Jan 2026 - May 2026 | |
| , | Liquidating, Mar 2025 | |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| , | Acquired by Sebia, Dec 2022 | |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| CROSSJECT | Dijon, France | Needle-free Injection |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| RepRegen | , | Gone, 2014 |
| , | Website down Jan 2026 - May 2026 | |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Myrexis | , | Liquidating 2013 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| , | Website taken over by compounding pharmacy, May 2026 | |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Pharmaron | Coventry, RI | API Manufacturing |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Corcym | London, UK | Implants, Instruments |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| GeoVax | Smyrna, GA | Vaccines |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| Memento Medicines | , | |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Visitube | , | No website Mar 2020 |
| , | No news 2019 - Jul 2026 | |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| CereSpir | , | No news 2020 - Nov 2024 |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| Velquest | , | Bought by Accelrys Jan 2012 |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Sage Science | Beverly, MA | DNA Fractionation |
| Pion | Billerica, MA | Dissolution Data |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| NewHeart Devices | , | Gone |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Targenics | , | No website Mar 2020 |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Alfacell | , | Now Tamir Biotechnology |
| Matritech | , | Assets bought by Matritech 2007 |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| Life Couriers | Munich, Germany | Diagnostics |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| Biotagenics | , | Renamed MedBiome |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| Nensius Research | , | Website Gone |
| Macleods Pharmaceuticals | Vagra, India | Generics |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Biotel | , | Acquired by CardioNet, 2010 |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| NovaLead Pharma | Pune, India | Small Molecules |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| , | Pivoted to blockchain, Sep 2025 | |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
|
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Therorna | Beijing, China | RNA Therapies |
| , | Renamed Proxoma, Jan 2026 | |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| QT Ultrasound | , | Renamed QT Imaging |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| Califia Bio | , | Shut down May 2020 |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| ProCrysta Biologix | , | Shut down 2018 |
| Clario | Philadelphia, PA | Clinical Services |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Sorbent Therapeutics | , | Gone post 2014 |
| NewVac | , | |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| , | Website under construction Dec 2024 - May 2026 | |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Microislet | , | Bankrupt 2008 |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| Microfluidics | Westwood, MA | High shear fluid processors |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
|
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Sygene Technologies | , | Website gone Nov 2018 |
| InterShunt | Maple Grove, MN | Minimally Invasive Interarterial Shunts |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| , | Merged with Cohance, May 2025 | |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
|
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
|
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| SynapDx | , | Shut down, Mar 2017 |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| Axplora | Pompey, France | CDMO Services |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| , | ||
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| Piramal | Sellersville, PA | CDMO |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| Novonesis | North Rocks, Australia | Enzymes |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Nuvation Bio | New York, NY | Oncology Treatments |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| , | Website down, CEO gone Apr 2026 | |
| GenturaDx | , | Bought by Luminex 2012 |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Cira Discovery | , | Website copyright 2003 |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| Etubics | , | Rolled into ImmunityBio |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Vernacare | Worksop, UK | Surgical Devices |
| Cryoniss | Deeside, UK | Bio Banking |
|
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| AB ANALITICA | Padua, Italy | Sequencing products |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Auris Medical | , | Renamed Altamira Therapeutics |
| NeurOptics | Irvine, CA | Pupillometry |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Cuda Pharmaceuticals | , | Presumed gone |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Novacta | , | Website Gone, no info |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| Trophea | , | Liquidated, Dec 2019 |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| Syndexa Pharm | , | Closed Jul 2013 |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| ProtonDx | London, UK | Diagnostics |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| Koelis | Meylan, France | Prostate Biopsy System |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Mirador Biomedical | , | Shut Down 2019 |
| Compucyte | , | Sold Assets to Thor Labs |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Noble | Orlando, FL | Auto-injector Trainers |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| Procertus | , | Website Gone, Apr 2016 |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Dundee Cell Products | , | Renamed DC Biosciences |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| JK Biopharma Solutions | , | Founder gone |
| Quantificare | Biot, France | Medical Imaging |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Hovione | Osaka, Japan | Contract Manufacturing |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| , | Website down Feb 2026 - Jul 2026 | |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Excelsyn | , | Bought by AMRI |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
|
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website taken over, Jan 2026 | |
| , | Website down Sep 2025 - Dec 2025 | |
| Icarus Medical | Charlottesville, VA | Knee Braces |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
|
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Dynacare | , | Bought by LabCorp 2002 |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Fujifilm Biotechnologies | Billingham, UK | Biologics Development & Manufacturing |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Angelica Therapeutics | , | Gone 2018 |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Graybug | , | Now Graybug Vision |
| PolyMedix | , | Bankrupt Apr 2013 |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Orbus Pharma | , | Website Gone |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| Anvyl | , | Website gone Jan 2021 |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| AddBIO | , | Gone Oct 2023 |
| Formurex | Stockton, CA | Contract Research |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| Novarad | Provo, UT | Imaging Software and Technology |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| , | Shut down Jan 2025 | |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| GNQ Insilico | Pleasanton, CA | In Silico Genomics |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| , | Subsumed into Synoptics | |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| Imris | Chaska, MN | Image Guided Therapy Solutions |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| , | Website down Oct 2025 - Feb 2026 | |
| Genocea Biosciences | , | Winding Down May 2022 |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| TRIFARMA | Chennai, India | APIs |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Cellf BIO | , | Website taken over Jan 2019 |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| , | Acquired by BD, Feb 2022 | |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Biotheneum | , | Gone |
| , | Shut down Oct 2023 | |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Zoll | Deerfield, WI | Medical Devices, Defibrillators |
| Vicus Therapeutics | , | Gone 2019 |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| JustRight Surgical | , | Renamed Bolder Surgical |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| IMUNA PHARM | Michalany, Slovakia | Contract Manufacturing |
| , | Website down Jan 2026 - Apr 2026 | |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
|
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| , | Acquire by Savillex, Nov 2024 | |
| OP2 Drugs | , | Website gone Jan 2020 |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| Aitia | Cambridge, MA | Analytics |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| Aspreva | , | Acquired by Vifor Pharma |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Quanticate | Raleigh, NC | Clinical Research |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| bioMerieux | Lombard, IL | Diagnostics |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| iCareDx | , | Renamed AcuamarkDx |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Stellartech Research | Milpitas, CA | Electronic device development |
| MiniVax | , | Gone Jan 2016 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Aresus Pharma | , | Seems folded in to Dermago |
| Quantificare | Suwanee, GA | Medical Imaging |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| BRAND | Wertheim, Germany | Liquid Handling |
| Protein Forest | , | Bought by Cell Biosciences |
| Epiomed Therapeutics | , | Gone |
| Satellos Bioscience | Markham, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| , | Renamed Ensera, Oct 2025 | |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Amigenics | , | Gone |
| Medelis | Thompson's Station, TN | Clinical Research |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| , | Website taken over Feb 2026 | |
| Wacker | San Diego, CA | Biologics CDMO |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| Viropro | , | Bankrupt 2015 |
| Minimus Spine | , | Only real employee now full-time at another company |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| , | Website down Apr 2026, seems bankrupt | |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| , | Became part of Accelerator, Dec 2025 | |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Digene | , | Merged with Qiagen |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
|
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Immunosyn | , | Charged with Securities Fraud |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| Biopticon | Princeton, NJ | Tumor Imaging |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| BioArctic | Stockholm, Sweden | CNS treatments |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Esper Therapeutics | , | Shut down 2016 |
| Translational Bioscience | , | |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Fujifilm Biotechnologies | College Station, TX | Biologics Development & Manufacturing |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| CisThera | , | Shut down Jan 2023 |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| In Cell Art | , | Website taken over Feb 2025 |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Plexanome | , | Gone 2018 |
| SenzaGen | Lund, Sweden | Genomic Assays |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| KALA BIO | Arlington, MA | Drug Delivery |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Eurosequence | , | Website gone Jan 2020 |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Splice Histology | Worcester, MA | Histopathology Services |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Stryker | Salt Lake City, UT | Medical Devices |
|
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
|
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| , | No news Jan 2021 - Jan 2026 | |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| CRI | , | Now BiomericsATL |
| Medtronic | Mounds View, MN | Medical Devices |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Lavipharm | Peania, Greece | Small molecules |
| Cancervax | , | Acquired by Micromet, May 2006 |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| MatTek | Ashland, MA | Cell Products, Services |
| , | Acquired by Xoma, Oct 2025 | |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| PlaSalus | , | Amateurish looking |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Stryker | San Jose, CA | Medical Devices |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| GemoPharm | , | No news 2017-2022 |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| , | ||
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| Conceptus | , | Bought by Bayer Apr 2013 |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Boston Scientific | Galway, Ireland | Medical Devices |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| , | Website down Dec 2025 - Jun 2026 | |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Argolight | Pessac, France | Microscopes |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| O-Ray pharma | , | Inactive Jun 2022 |
|
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Nanovelos | , | Subsumed into Nanogroup |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Avatar Medical | Paris, France | Surgical Visualization |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Appia Bio | , | Shut down Aug 2025 |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
|
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Promethera Biosciences | , | Renamed Callaion |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| , | Website down Sep 2025 - Dec 2025 | |
|
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| MedShape | , | Acquired by DJO, Apr 2021 |
| Codon Devices | , | Closed Apr 2009 |
| , | ||
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
|
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Senzime | Uppsala, Sweden | Devices |
| Cancer Insight | , | Renamed LumaBridge |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Optimata | , | Shut down May 2019 |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| AC Diagnostics | , | Website from 2004 |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| AbbVie | Waco, TX | Contract Manufacturing |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| Ansata Therapeutics | , | Out of business 2007 |
|
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| Orthologic | , | Now Capstone Therapeutics |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| Barrier Therapeutics | , | Bought by Stiefel |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| NemaPharm | , | Defunct? |
| TriVirix | , | Now Nortech Life Sciences |
| Kona Medical | , | Closed, Dec 2016 |
| , | Winding down Jan 2026 | |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Celest Therapeutics | , | |
| Perlegen | , | No Site |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
|
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| , | Website down Jan 2026 - May 2026 | |
| , | Merged with DefiniGEN to become pixl.bio | |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| , | Pivoted to defense, Feb 2026 | |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Bioventus | Cordova, TN | Orthobiologics |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Piramal | Mahad, India | CDMO |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Twistnostics | , | Renamed Scanogen |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| AVEO Oncology | Boston, MA | Small Molecules |
| Innovative BioTherapies | , | Gone |
| ChondroGene | , | Now GeneNews |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Rafagen | , | Website redirecting to Rophibio |
|
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Biomax Informatics | , | Acquired by Labvantage |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Rgene | , | Late business filings Aug 2021 |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Universal Precision Instruments, Inc. | , | |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| HarkerBIO | , | Shut down Apr 2019 |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Ribocept | , | Defunct |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| Medice | Iserlohn, Germany | Small Molecules |
| Phenomyx | , | Gone Jun 2019 |
| Synosia Therapeutics | , | Acquired by Biotie |
|
Lyon, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| preclinics | Potsdam, Germany | Contract Research |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| InfraReDx | Bedford , MA | Medical Devices |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| , | Website down Dec 2025 - Apr 2026 | |
| Infinity Bio | Baltimore, MD | Reactome Services |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| , | Shut down Oct 2025 | |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| TranS1 | , | Renamed Baxano Surgical |
| Apofore | , | Shut down, Dec 2015 |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Precision Research Institute | , | Shut down Apr 2024 |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| MedGyn Products | Westmont, IL | OBG Devices |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| , | Acquired by Versiti, Jul 2023 | |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Anergix | , | Shut down Mar 2009 |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| , | Subsumed into parent, Intermountain Healthcare, Jun 2026 | |
| 1CellBio | , | Gone Jun 2019 |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| HebeCell | Natick, MA | Cell Therapies |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| , | Renamed aMBR Genomics, Jun 2026 | |
| Pharmazz | Greater Noida , India | Small Molecules |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| GTX Medical | , | Renamed ONWARD |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| EMD Serono | Boston, MA | Biologics |
| Arete Therapeutics | , | Out of Business |
| Wacker | Amsterdam, Netherlands | Biologics CDMO |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Obexia | , | Gone |
| Microbia-pe | , | Renamed Microbia |
| , | No news 2020 - Nov 2025 | |
| ObvioHealth | New York, NY | Clinical Study Software |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Genoma | , | Website gone May 2021 |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
|
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
|
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
|
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Stromedix | , | Bought by Biogen Idec 2012 |
| CranioVation | , | Shut down Jan 2022 |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| Sokol GxP Services | Bensalem, PA | Equipment Qualification Services |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| , | Winding down Apr 2026 | |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| PX Biosolutions | , | Gone |
| Pristine Bioproduction | , | Not a going concern |
| XtalPi | Beijing, China | AI Drug Design |
| Anoixis | Natick, MA | Pharmacometric Services |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Comac Medical | Sofia, Bulgaria | European CRO |
| , | Website down Apr 2026 - Aug 2026 | |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| VLST Corp | , | Wound Down, Jun 2013 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| Vernay | Griffin, GA | Fluid Control Solutions |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| Norgine | Milan, Italy | Specialty Pharma |
| Spirometrix | , | Renamed Spirosure |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| BojiMed | Guangzhou, China | Clinical Research |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Genecure | , | Shut down Sep 2021 |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| BGI | Kobe, Japan | Genetic Testing |
| , | Acquired by Aptean, Oct 2016 | |
| Viatris (2) | Hyderabad, India | Small Molecules |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Biokit | , | Rolled into Werfen |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Athlon Pharma | , | No news since 2006 lawsuit |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| , | Renamed Aspen Neuroscience | |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| , | Website taken over Feb 2026 | |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| Advaned Viral Research | , | Shut down 2009 |
| , | Acquired by Cell Return, Dec 2019 | |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Qynapse | Boston, MA | Imaging Analysis |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Protein Metrics | Boston, MA | Protein characterization software |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| GeneTrol | , | Merged with CytoPharm |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Pharsight | , | Merged with Tripos to become Certara |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Louisville Bioscience | , | Now LBIdx |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Medelis | Ypres, Belgium | Clinical Research |
| Pace | San German, PR | Analytical Testing, CDMO |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| Fonar | Melville, NY | Upright MRI |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| Pharmaron | Cardiff, UK | R&D Services |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| Veeva Systems | Shanghai, China | Life Science Software |
| Amphora Medical | , | Shut down May 2019 |
|
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| PumasAI | Dover, DE | Pharmacology, Modeling Software |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| , | Website down Jun 2025 - Dec 2025 | |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
|
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| DL Develop | , | Website gone, Dec 2018 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Redpoint Bio | , | Inactive |
| NeurAegis | , | Seems gone, Sep 2022 |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| Oncogen | , | Acquired by BMS, 1986 |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Remepy | New York, NY | Software-Pharmaceutical Integration |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Artivila Biopharma | Shenzhen, China | Small Molecule Drugs |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| MerciaPharma | , | No updates 2014-2023 |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Niveus Medical | , | Closed Dec 2017 |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| Wyeth | , | Bought by Pfizer |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| ARTham Therapeutics | , | Shut Down late 2023 |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| , | business filings late Oct 2023 - Oct 2025 | |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Life Analytics Group | , | Gone |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Helsinn | Dublin, Ireland | Small Molecules |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| IvWatch | Newport News, VA | IV infiltration detection |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| GliaGen | , | Renamed CaCy Therapeutics |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| LinkChem | Shanghai, China | CDMO |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| , | No news Mar 2021 - Jan 2026 | |
| Diagast | Loos, France | Transfusion Reagents |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| DNALite Therapeutics | , | Renamed Particella |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Biomedica | , | Now part of Oxford Biomedica |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| TCG GreenChem | Ewing, NJ | |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| BIND Biosciences | , | Now BIND Therapeutics |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| ApcinteX | , | Centessa Company |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| SolaranRx | , | Website taken over |
| , | Shut down Fall 2025 | |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Angiosyn | , | Acquired by Pfizer 2005 |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Dornier MedTech | Sillingy, France | Urology Devices |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| Orochem | Naperville, IL | Reagents, Automation |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Tripos | , | Bought by Certara |
| , | LI gone Jul 2026; Website down Jun 2026 - Jul 2026 | |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Xtuit | , | Gone Jul 2018 |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Zivena | , | Gone |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| , | Website down Feb 2026 - Aug 2026 | |
|
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| VaxInnate | , | Dissolved Feb 2017 |
| TauTaTis | , | Shut down 2011 |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Traversa Therapeutics | , | Bankrupt |
| Halo Genomics | , | Bought by Agilent |
| Neotech | , | Website down Jan 2019 |
| Clinical Microbiomics | , | Merged into cmbio |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Signatur Biosciences | London, UK | PCR Platform |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| BioAMPS | , | Gone |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| , | Reportedly Closed Mar 2026 | |
| Tecomet | Woburn, MA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| ReactDx | Melbourne, FL | Wireless Monitors |
| , | Website down Dec 2025 - Mar 2026 | |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| ARC Medical | , | Acquired by Typenex Medical |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Cytely | Lund, Sweden | Automated Assays and Workflows |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| ZipBio | Seattle, WA | Compact Proteins |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Applied Integrin Sciences | , | Gone |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| , | Website down Feb 2026 - Jul 2026 | |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| , | Website down Dec 2025 - Apr 2026 | |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| , | Website down Sep 2025 - Dec 2025 | |
| ADS Biotechnology | , | Bankrupt 2014 |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| Haini Pharmaceutical | Shanghai, China | Generics |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Genemod | Edmonds, WA | Lab management software |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| iuvo | Rochester, NY | Ophthalmic Clinical Research Services |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| Selah Genomics | , | Seems gone after being sold back to founder |
| AlcaSynn | , | Renamed ChironWells |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Cholestech | , | Now Alere |
| Cristers | Suresnes, France | Generics |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Venebio | Glen Allen, VA | Consultants |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Glen Research | Sterling, VA | Oligos |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| GenomeKey | Bristol, UK | IVD Device |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| AdrenaCard | , | Gone 2019 |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| EmpowerPharm | , | Shut down |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| Biocorp | Issoire, France | Medical Devices |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| Aviria Biosciences | , | Disappeared |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| FluoroPharma | , | Shell Company |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
|
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | ||
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
|
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Lacer | Barcelona, Spain | Small Molecules |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
|
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
|
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Resilience | Mississauga, ON | Biomanufacturing |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| GIVAX | Boston, MA | GI Vaccines |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Optherion | , | Sold Assets, Still Exists |
| , | Acquired by Olon, 2024 | |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Cytiva | Piscataway, NJ | Medical Devices |
| Axplora | Raubling, Germany | API CDMO |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Cellenion | Lyon, France | Single Cell Testing |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Nanobac Pharmaceuticals | , | Gone |
| Nura Bio | South SF, CA | Small Molecule |
| Amaranth Medical | , | Website gone, Apr 2019 |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
|
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| , | Renamed Alethio Therapeutics | |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Chanelle Pharma | Amman, Jordan | Generics |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| , | Website down Dec 2025 - Apr 2026 | |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Piper Therapeutics | , | Website gone May 2020 |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| , | Renamed Flourish Biologics, Jul 2026 | |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| Kelliop | Newark, CA | Diagnostic Reader |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| , | Renamed medac pharma production, Apr 2026 | |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Formex | , | Merged into BioDuro, Nov 2015 |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| NeuroFx | , | Renamed Theratome Bio |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| RhinoCyte | , | Website moved to a marketing agency domain |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| , | Website down Aug 2025 - Jan 2026 | |
|
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Senetek | , | Not sure what happened, no site, seem gone |
| , | Renamed Solario Bio | |
| DiObex | , | Shut Down 2009 |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| RxGen | , | Renamed Virscio, Jan 2020 |
| CNS Research | , | Seem gone, 2020 |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| PsiThera | Watertown, MA | Oral Small Molecules |
|
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| , | Shut down Sep 2025 | |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Boston Biokeys | , | Gone June 2017 |
| Adlyfe | , | Gone, no info |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Cibiem | , | Shut down May 2021 |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Medreich | Bengaluru, India | CDMO |
| OrthoData | , | Renamed Intellirod Spine |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Iontas | , | |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| SERB Pharmaceuticals | Dubai, UAE | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Labopharm | , | Bought by Paladin 2011 |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
|
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| Longevica Therapeutics | Belmont, CA | Longevity Therapies |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| , | Website down Oct 2025 - Feb 2026 | |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| BioMAS | , | Ceased operating, Jul 2016 |
| Kirgen | Shanghai, China | Lab Supplies |
| Acrosian | Princeton, NJ | Biometrics CRO |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Zelos Therapeutics | , | No site |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| Syneos Health | Princeton, NJ | Clinical Development |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| TME Pharma | Berlin, Germany | L-aptamers |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Satya | Hyderabad, India | Small Molecule |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| NIOX | Oxford, UK | Asthma management device |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| Novo Nordisk | Beijing, China | Inflammation Research |
| Axplora | Chennai, India | API manufacturing |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| GeneoDx | , | Website gone Oct 2019 |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| PredictImmune | , | Shut down Nov 2023 |
| Macrogen | , | Renamed Psomagen, 2019 |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| SpinalMotion | , | Website gone, 11-30-14 |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| Genopraxis | , | Founder has new job, Jul 2021 |
| NextImmune | , | Renamed NXI Therapeutics |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Fuse Diagnostics | Cambridge, MA | Molecular Diagnostics |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| PharmaDerm | , | Part of Sandoz |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| , | Shut down Jan 2025 | |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| CyteGen | , | 2015 founded, website never active |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| Quanticate | Hitchin, UK | Clinical Research |
| DMD Therapeutics | , | Gone Nov 2018 |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| Nasseo | , | Gone |
| DiagnoSearch | Thane, India | Clinical Research |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| Aerovance | , | Gone, don’t know where |
| CELLSCRIPT | Madison, WI | RNA for Translation |
|
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| , | Acquired by Sun Pharma, May 2025 | |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| , | Acquired by Glaukos, Aug 2025 | |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| , | Acquired by Waters, 2023 | |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| Aviv Biomedical | , | Shut down 2018 |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Folia Biotech | , | Website Gone May 2018 |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| Solvanix | , | Shut down Nov 2023 |
|
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| ProSci | Poway, CA | Antibodies, etc. |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Partek | , | Acquired by Illumina, May 2024 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Inovio Biomedical | , | Seems gone |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| , | No news 2015 - Aug 2026 | |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Ergomed | Kiev, Ukraine | Clinical Research |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
|
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
|
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| NEXGEL | Langhorne, PA | Hydrogels |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| SK Biotek | , | part of SK pharmteco |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Acuvax | , | Pivoted to investments, 2014 |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| Afaxys | Charleston, SC | Women's Health |
| South Coast Clinical Trials | , | |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Genomica | , | Shut down Sep 2022 |
| Northstar Neuroscience | , | Dissolved |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| , | Website down May 2025 - Nov 2025 | |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| Squarex | , | Gone as of Oct 2021 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Advarra | Columbia, MD | Regulatory Consulting |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| RJS Biologics | , | Shut down Feb 2019 |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Grannus Biosciences | , | Gone |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Kirax | , | Website Gone |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| , | Website taken over Jun 2026 - Aug 2026; LI gone Jul 2026 | |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| Calypte Biomedical | , | Gone |
| IMMY | Norman, OK | Fungal Diagnostics |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Virometix | Schlieren, Switzerland | Vaccines |
| Linical | Stuart, FL | Clinical Research |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| Alphatec Spine | , | Renamed Atec Spine |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| NKMax America | , | Renamed NKGEN Biotech |
|
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| , | No news 2021 - Jun 2026 | |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Facet Biotech | , | Bought by Abbott 2010 |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| , | Website down Oct 2025 - Feb 2026 | |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| Newgen Biopharma | , | Suspended trading due to scandal |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Angioslide | , | Gone, Oct 2009 |
| , | Shutdown Oct 2025 | |
| , | Website down Jan 2026 - Mar 2026 | |
| 3B BlackBio | Bhopal, India | PCR products |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Lung LLC | , | Renamed Lung Biotechnology |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Combs Lab | , | Website gone Dec 2016 |
| Par Health | St. Louis, MO | Generics |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| Essential Pharma | Egham, UK | Generics |
|
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Acquired by Embecta, Mar 2026 | |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| Acculysis | , | Website gone, sole employee with Agilent now |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Lupin | Maharashtra, India | Generics |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| , | Acquired by Generic Specialties, May 2016 | |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| , | Website down Jan 2026 - May 2026 | |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| VaxNewMo | , | Renamed Omiose |
| Alkermes | Dublin, Ireland | Small Molecules |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Bayer | Barcelona, Spain | Small Molecules |
|
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Bionas Discovery | , | Website gone Jun 2018 |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| HIPRA Biotech Services | Girona, Spain | Biologics CDMO |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Bayer | Mexico City, Mexico | Small Molecules |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Kereos | , | Seems gone |
| Spring Discovery | , | Renamed Spring Science |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| Jina Pharmaceuticals | , | |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| , | Website down Feb 2026 - Jul 2026 | |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| Celula | , | Acquired by NeoSeq |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Serotiny | , | Acquired by J&J, 2023 |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Affivant | , | Part of Roivant |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Axium Pharmaceuticals | , | Dissolved |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Tempered Biosciences | , | Absurd website has to be gone |
| MLAB Biosciences | Needham, MA | Biologics |
| Baccuico | , | Renamed Bactobio |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| , | Acquired by Charles River, Apr 2019 | |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Creative Enzymes | Shirley, NY | Enzymes |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| , | Acquired by Maverix Medical, Dec 2023 | |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Alcon | Irvine, CA | Eye-Care Products |
| NascaCell | , | German Aptamer company, not sure of fate |
| , | Founder left Jul 2025, still on website Jul 2026; LI gone Jul 2026 | |
| Bicycle Therapeutics | Lexington, MA | Peptides |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| , | No news 2020 - Jun 2026 | |
| Pharmaron | Tianjin, China | R&D Services |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| , | Website down Feb 2026 - Jun 2026 | |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Apolife | , | Renamed Biosavita |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Sprna | , | Website gone Jan 2020, no info |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| , | Website down Oct 2025 - Jan 2026 | |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| TRIFARMA | Rozzano, Italy | APIs |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Aplagen | , | No activity since 2008 |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| TumorEnd | , | Website gone Feb 2019 |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| , | No news 2018 - May 2026 | |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| AJES Life Sciences | , | Renamed L2P Research |
| , | Website down Jan 2026 - May 2026 | |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Covalent Bioscience | , | Shut down, 2025? |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Protein Polymer Technologies | , | Basically Gone |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| HistoIndex | Glasgow, UK | Digital Pathology |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Biotix | San Diego, CA | Lab Consumables |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| Qlucore | Lund, Sweden | Visualization Software |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| , | Seems inactive Jan 2026 | |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| Aixa Bio | Cambridge, MA | AI genomics |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| IBA Analytics | , | Website gone Jul 2015 |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| , | Website down Jan 2026 - May 2026 | |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| , | Acquired by Crypto Group, Jan 2025 | |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| MIFCOR | , | Founders both gone Feb 2021 |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| Partner Therapeutics | Lexington, MA | Biologics |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| Stada | Bad Vilbel, Germany | Generics |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Kerecis | Arlington, VA | Wound Healing |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| Medtronic | Minneapolis, MN | Medical Devices |
| ALTx Therapeutics | , | Small Molecule Therapies |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| Excaliard | , | Bought by Pfizer 2011 |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
|
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| SEQENS | Ecully, France | APIs, Ingredients |
| Sunol Molecular | , | Assets sold 2005 |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| , | Website down Nov 2025 - Apr 2026 | |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| Prommune | , | |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| Terapio | , | Website Gone, Sep 2020 |
| MediQuest Therapeutics | , | Gone? |
| LabTwin | , | Merged with Labforward |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Xencor | Pasadena, CA | Antibody Discovery |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| Neugenesis | , | Bought by Intrexon, 2011 |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| , | No news 2020 - Jun 2026 | |
| LeukoSite | , | Acquired by Millennium 1999 |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| , | Website down Oct 2025 - Jan 2026 | |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Profil | Neuss, Germany | Clinical Research Services |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Menarini | L'Aquila, Italy | Small Molecules |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Biovail | , | Merged with Valeant |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| Zambon | Bresso, Italy | Small Molecules |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Gentel Bio | , | Ceased Operations 2012 |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| SEQENS | Pune, India | Analytical method validation, API development |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| WntResearch | , | Shell acquired by Opsy |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| , | Website under construction Feb 2025 - Jan 2026 | |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| Ingenetix | Wien, Austria | PCR Products |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Fujifilm Biotechnologies | Morrisville, NC | Biologics Development & Manufacturing |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Kalypsys | , | Gone |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| MediWound | Yavne, Israel | Wound & Burn Care |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Resprotect | , | No update since 2012 as of 2020 |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| Bioprosthetics | Newark, DE | 3D-printed bone grafts, skin grafts, and eye lenses |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| Metabasis | , | Bought by Ligand |
| AnaBioTec | , | Now Anacura |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| Claritas Genomics | , | Closed Jan 2018 |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| Curadev | Kent, UK | Immuno-oncology |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| Klogene Therapeutics | , | Gone 2019? |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Bone's Technology | Hong Kong, China | Bone Density Analysis, Surgical Planning |
| , | Liquidated Jun 2025 | |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| Getinge | Mahwah, NJ | Medical Technology |
| AlphaMab Oncology | Suzhou, China | Biologics |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| , | Renamed Faeth Therapeutics, Jun 2026 | |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Quest Clinical Research | , | Now part of eStudysite |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| 14M Genomics | , | Shut down, Feb 2016 |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Tapestry Pharmaceuticals | , | Gone |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Enterey | Irvine, CA | Life Science Consulting |
| Cell Technology | , | Acquired by ICT |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| , | Website taken over Jun 2026 - Aug 2026 | |
| , | No news Jun 2021 - Jan 2026 | |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| EmerVax | , | Renamed Circurna |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| NuLife Sciences | , | Shell acquired for a security business |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Neurosave | , | Gone 2018 |
| Gene Techno Science | , | Renamed Kidswell Bio |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| , | Acquired by Instem, Jul 2025 | |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| CMP Pharma | Farmville, NC | Small Molecules |
| AltaRex | , | Gone |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| PPL Therapeutics | , | Sold in 2003 |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| Purinomia Biotech | , | |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| , | Shut down Sep 2025; fka GenoFAB | |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| CardiRen Biomedical | , | Gone Aug 2017 |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| , | Acquired by Instem, Jul 2025 | |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Accord Healthcare | Ahmedabad , India | Generics |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Indexus Biomedical | , | Shut down 2018 |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Cerebroscience | , | One employee, website gone |
| , | Acquired by Arterex, Jun 2023 | |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| BHR Pharma | , | Subsidiary of Besins |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Osteolab | , | Spam site |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| Nuredis | , | Shut Down Apr 2021 |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Vexev | Surry Hills, Australia | Vascular Imaging |
| , | Liquidating Jun 2026 | |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Indomo | Virtual, US | Acne Treatment |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Oticon | Smørum, Denmark | Hearing Aids |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Hepalink | Shenzhen, China | Heparin API |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| , | Website down Sep 2025 - Dec 2025 | |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| , | Assets Acquired by Klotho, Sep 2025 | |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Pharmexa | , | Merged into Affitech, May 2009 |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Gataca | , | Gone |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| , | ||
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
|
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| MetaMol Theranostics | , | Gone |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Lupin | Baltimore, MD | Generics |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| CMD Medtech | Columbus, OH | Medical Device Development |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Life Stem Genetics | , | Basically gone |
|
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| ERT | , | Renamed Clario, Nov 2021 |
| Covenant Therapeutics | , | Gone |
| , | Website down Feb 2026 - Jul 2026 | |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Urogenix | , | Acquired by Astellas |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| , | Website down Aug 2025 - Dec 2025 | |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| CytoVera | , | Gone June 2017 |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Green Cross | , | Renamed GC Pharma |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Centricity Research | Toronto, ON | Clinical Research |
| Ampac Analytical | , | part of SK pharmteco |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| , | Acquired by Stryker, Sep 2024 | |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| LightMed | , | |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Mendelian | London, UK | Rare Disease Diagnosis |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Ottobock | Königsee, Germany | Prosthetics |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| , | Merged with Avere Therapeutics, Jul 2026 | |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Medtronic | Memphis, TN | Medical Devices |
| Aliquot Solutions | , | Shut down Oct 2024 |
| Abbott | Singapore, Singapore | Diagnostics |
| Integer | Salem, VA | Medical & Surgical Devices |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Stryker | Flower Mound, TX | Medical Devices |
| Roche | Laval, QC | Diagnostics |
| , | Website down Feb 2026 - Jul 2026 | |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
|
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Assets bought by Bruker during restructuring, Jul 2026 | |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Samil Pharmaceutical | Seoul, Korea | Eye Drops, Aseptic Filling, Formulation |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Vivid Genomics | , | Shut down Sep 2023 |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Aimsn Medical | Shanghai, China | Devices, Implants, First Aid |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| AblaCare | , | Renamed May Health, Sep 2022 |
| , | Website down Mar 2026 - Aug 2026 | |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| , | Seems to be News website, Jan 2026 | |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| One Drop | , | Gone Dec 2024 |
| Mojave Therapeutics | , | Gone |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Reach Separations | Nottingham, UK | Purification Services |
| Xhale | , | Acquired by Philips, Aug 2018 |
| Unilife | , | Bankrupt, Apr 2017 |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Wacker | Munich, Germany | Polymers, Resins |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| , | Renamed Cyclana Bio | |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Antigenics LLC | , | Now Agenus |
| , | Renamed Medici Therapeutics, Dec 2024 | |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| , | Renamed Pixl.bio, Nov 2025 | |
| Inspirata | Tampa, FL | Cancer Insights |
| Rezolute | Bend, OR | Biologics |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Anazen Diagnostics | , | Part of Cardiox |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| InnoVoyce | Boston, MA | ENT Lasers |
| , | Website taken over May 2026 | |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| Empatica | Cambridge, MA | Seizure Detection |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| Vante BioPharm | , | Rebranded at Sebra |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| Octagen | , | Assets bought by Ipsen, 2008 |
|
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| Gentell | Yardley, PA | Wound Care |
| Global Cell Solutions | , | Gone Apr 2018 |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Belyntic | Berlin, Germany | Immunotherapies |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| , | Acquired by Chiesi, Apr 2023 | |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| , | ||
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Inform Genomics | , | Website Gone Nov 2018 |
| Boston Scientific | Cork, Ireland | Medical Devices |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| KyooBe Tech | Leinfelden-Echterdingen, Germany | Contract Vaccines, Cell, Gene Therapy Manufacturing |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Stago | Taverny, France | Diagnostics |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
|
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Makefield Therapeutics | , | Website Gone |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| Tecomet | Bristol, PA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Abazyme | , | Dissolved Jun 2017 |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| BioXpert | , | Website gone Mar 2017, employees gone |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| , | Seems renamed to Lusis Biosciences | |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| Y's Therapeutics | , | Website Gone |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| OraSure | Bethlehem, PA | Diagnostics |
| Glysantis | , | Shut down Late 2020 |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Nesch, LLC | , | Website gone Oct 2018 |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| nitec Pharma | , | Merged with Horizon Pharma |
| ArisGen | , | Only employee has four other jobs |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| Nanosonics | Indianapolis, IN | Ultrasound |
| GeneAssess | , | Gone |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Padagis | Allegan, MI | Generics |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| Aadigen | , | Renamed Aanastra |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| Alxerion Biotech | , | Gone May 2021 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| SomaServe | , | Renamed ViaNautis Bio |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| , | Liquidating Jul 2025 | |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| Aspira Scientific | , | Gone Nov 2015 |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| ActivaTek | , | Acquired by North Coast Medical |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| JD Bioscience | Seoul, Korea | Small Molecules |
| Veeva Systems | Dublin, OH | Life Science Software |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| MolPlex | , | Insolvent, 2016 |
| Cytecs | Münster, Germany | Cell Analysis |
| Cellink | Kyoto, Japan | Bioprinting |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Therabest | Seoul, Korea | iPSC |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Talima Therapeutics | , | Closed 2011 |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| , | Shut down 2024 | |
| Pear Bio | London, UK | Cancer Treatment Selection |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Multerra Bio | , | Bankrupt May 2021 |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| Groton Biosystems | , | Gone before Jun 2015 |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| , | Acquired by IQVIA | |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Stasys Medical | , | Shut down Feb 2025 |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
|
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| , | Renamed Verge Medical, Mar 2025 | |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| MantraPharma | Lévis, QC | Generics |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| LinKinVax | , | Rebranded as EnnoDC |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| Glyphic Biotechnologies | Berkeley, CA | Protein Sequencing Platform |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| RFE Pharma | , | Gone 2019 |
| SilaGene | , | Gone |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| BioPhyZica | , | Gone 2016 |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| , | Website down Mar 2026 - Aug 2026 | |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Enzo Biochem | , | |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| Pneumolabs | , | Dissolved Sep 2018 |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Abgenix | , | Bought by Amgen 2006 |
| Stryker | Mahwah, NJ | Medical Devices |
| PKPD International | , | Attack website |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
|
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Maxwell Biosciences | Austin, TX | Antivirals |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Precision Virologics | , | Precision Virologics |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| , | Renamed Cerenome, Aug 2026 | |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| , | Shut down Oct 2024 | |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| , | ||
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Erbe | Tübingen , Germany | Surgical Systems |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Phase Forward | , | Bought by oracle |
| Dante Labs | , | Seems to be Dante Genomics now |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Genyous Biomedical International | , | Presumed Gone |
| , | Renamed ABS Bio | |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| , | Acquired by AbbVie, Aug 2025 | |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| Sopharma | Sofia, Bulgaria | Generics |
| INTIO | , | Website down Jan 2021 - May 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| Synlogic | , | Shut down Sep 2024 |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| , | Gone Jul 2026, portions acquired by Axol Bioscience | |
| KXT bio | , | Shut down 2019 |
| CellXplore | , | Gone |
| Katalyst Healthcare and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| Vie Diagnostics | , | Renamed Phoresa |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
|
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Sonavex | Baltimore, MD | Ultrasound |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| ProPharma Group | Bozeman, MT | Consulting |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| , | Liquidation, Jun 2025 | |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Sharp | Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| Wellinks | New Haven, CT | Portable Nebulizer |
| ClinArt | , | Now ClinArt MENA |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Boston Scientific | Spencer, IN | Medical Devices |
| , | No news 2021 - Jul 2026 | |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| , | Website taken over, Feb 2026 | |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| , | Website down May 2025 - Dec 2025 | |
| ProPharma Group | Raleigh, NC | Consulting |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Simpirica Spine | , | Became Empirical Spine |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| , | Acquired by AstraZeneca, Dec 2025 | |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Protelica | , | Dissolved, Dec 2006 |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Salvat | Madrid, Spain | Small Molecules |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| NeoPharm | , | Merged with Insys Therapeutics |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Clarapath | Hawthorne, NY | Pathology Device |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| IQVIA | Parsippany, NJ | Clinical Research |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Cytoplex Biosciences | , | Gone |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| BioMap | Palo Alto, CA | AI Models |
| Biogenes | Berlin, Germany | Antibodies |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
|
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| Zai Lab | Beijing, China | Small Molecules |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Biovays | , | Website Gone |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| , | Acquired by Lantheus, Jan 2025 | |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
|
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Iktos | Paris, France | AI for New Drug Design |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
|
Alderley Park, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| hC Bioscience | , | Shut down Mar 2025 |
| Tecomet | Sheffield, UK | Casting, CNC Machining, EDM, Finishing, Forging, Heat Treatment |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| Compass Biotech | , | Defunct |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
|
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| SuraMedical | , | Most employees left, not registered in MN |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| NuVascular Technologies | , | Shut down Nov 2021 |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| C3 Jian | , | Now C3J Therapeutics |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| PTM BioLabs | , | Renamed PTM BIO |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| KAI Research | , | Acquired by Navitas Life Sciences |
| BG medicine | , | Gone 2019 |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| SERB Pharmaceuticals | Paris, France | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| Antabio | Labège, France | Antibacterial drugs |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Stemnovate | Cambridge, UK | Research Cells |
| GliaMed | , | Website copyright 2009, seems defunct |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Barc Lab | , | Renamed Cerba Research |
| Bluestar Genomics | , | Renamed ClearNote Health |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| SteriTech | Sligo, Ireland | Process Equipment |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| , | Shut down Apr 2026 | |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| Lumen Bioscience | Seattle, WA | Biologics |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Cleave Therapeutics | , | Shut down Jul 2023 |
|
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
|
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Actavalon | , | Shut down Dec 2020 |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Spherics | , | Bankrupt |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Blau Farmaceutica | São Paulo, Brazil | Biosimilars |
| Theranostech | , | Renamed Sandia Biotech |
| PeriCor Therapeutics | , | Website Gone |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Ansh Labs | Webster, TX | Diagnostics Products |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| CytRx | , | Renamed LadRx Sep 2022 |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| , | Now part of LTS, Dec 2025; fka Renaissance Pharma | |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Ipsen | Wrexham, UK | Biologics |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| , | Acquired by IASO Biotechnology, Jul 2026 | |
| GT Biologics | , | Renamed 4D Pharma Research |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| , | Gone Aug 2026; Medigene spinout | |
| Stat One | Morrisvile, NC | eClinical |
| NovaDel Pharma | , | Business dissolved 2014 |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| Chrysalis | Morrisville, NC | GMP Space |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| MOgene | St. Louis, MO | Genomic Services |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
|
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
|
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| DxTerity | Torrance, CA | Genomic Testing |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
|
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
|
Cambridge, UK | Isogenica: VHH antibody discovery CRO. World's largest synthetic libraries, 100+ programmes, clinical candidates, discovery timelines cut in half. |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Commave Therapeutics | , | |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
|
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Orion | Espoo, Finland | Drugs, Diagnostics, Veterinary medicine, etc. |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| CoreBiome | , | Merged into Diversigen |
| , | Acquired by J&J, Dec 2025, $3.05B | |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| REPROMEDIX | , | Gone 2012 |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| Roche | Penzberg, Germany | Diagnostics |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Wacker | Jena, Germany | Biologics CDMO |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
|
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website taken over Mar 2026 | |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| , | Sold product Jul 2024; VP Sales gone Jun 2024 still on website Aug 2026 | |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| Victory Pharma | , | Assets Acquired by Shionogi |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| Micrologix Biotech | , | Renamed Migenix |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| , | Inactive 2025 | |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| Corza Medical | Somerset, UK | Surgical Devices |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Haupt Pharma | , | Merged with Aenova |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| Intellirod Spine | , | Sold Assets late 2020 |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| Biocode Hycel | , | Website gone |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
|
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
|
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| Soluble Systems | , | Renamed Solsys Medical |
| Epixis | , | Acquired by VBI Vaccines |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| Totient | , | Acquired by Absci, Jul 2021 |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| GenSensor | Nantes, France | Process Analytical Technology |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| DxTech | , | Seems gone. No info Dec 2015 |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| Ergomed | Raleigh, NC | Clinical Research |
| ActivBiotics | , | Assets sold off Feb 2008 |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
|
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| SGS Quay Pharma | , | |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Incyte | Wilmington, DE | Small Molecules |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Pfizer | Clondalkin, Ireland | Biologics |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| , | Website down Nov 2025 - Apr 2026 | |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| Acumed | Madrid, Spain | Medical Implants |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| TFS | Lund, Sweden | Clinical Research |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| , | Website down Dec 2025 - Apr 2026 | |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| Eden Biodesign | , | Bought by Watson |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| Bracco | Plainsboro, NJ | Imaging |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Pharmaron | Hertfordshire , UK | R&D Services |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| , | Website down Feb 2026 - Jul 2026 | |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| BioMendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Lab Owl | , | Part of Inflexion Point |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| Macleods Pharmaceuticals | Tembhode, India | Generics |
| VivoSphere | Auburn, AL | Human-like Research Tissue |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Pirche | Grünwald, Germany | Transplant Matching |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Scholar Rock | Cambridge, MA | Biologics |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Anulex Technologies | , | Closed 2014 |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| , | Website down Jul 2025 - Dec 2025 | |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| Droice | New York, NY | AI Clinical Data |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| , | Acquired by Scantox, Sep 2024 | |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Bonenta | , | Website gone |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| , | Website down May 2025 - Sep 2025 | |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
|
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| , | Website down Aug 2025 - Jan 2026 | |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| SutroVax | , | Renamed VaxCyte |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Iomai | , | Bought by Intercell 2008 |
| Algenics | , | Website gone Dec 2015 |
| CardioEphEx | , | Shut down Dec 2020 |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| , | ||
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| mibe Arzneimittel | Brehna, Germany | Generics |
| Genomadix | Kanata, ON | Portable PCR |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Tolmar | Fort Collins, CO | Small Molecules |
|
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| , | Website down Jun 2025 - Dec 2025 | |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| MedinCell | Jacou, France | API Delivery Gel |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| Afferon | , | Gone, no info |
| ScionxBio | Cambridge, UK | Extended-release RNA |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| , | Website down Jan 2026 - May 2026 | |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| , | Subsumed into Synoptics | |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Zai Lab | South SF, CA | Small Molecules |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| DDi | Monmouth Junction, NJ | Clinical Software |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Akermin | , | Closed |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| Nina Biotherapeutics | , | Gone, after 2015 |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
|
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Jaleva Pharmaceuticals | , | Gone |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Amarox | Riyadh, Saudi Arabia | Generics |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| G6 Spine | , | Gone 2017 |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| American Regent | Shirley, NY | Generics |
| StromaCyte | , | Small time, no info. Defunct |
| CanSino Biologics | Tianjin, China | Vaccines |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
|
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Viva Biotech | Shanghai , China | Contract Research |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| Emmes | Rockville, MD | Clinical Research Organization |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Evalve | , | Owned by Abbot Vascular |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| iTherapeutics | , | Doubt they do anything |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| , | Website 404 Sep 2025 - Apr 2026 | |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| DanPET | , | One guy, Feb 2024 |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| , | Website gone Feb 2026 | |
| Fujifilm Biotechnologies | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Kastle Therapeutics | , | Closed May 2018 |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| Cell Matrix | , | Acquired by Cancervax |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| AntiOp | , | Tech sold Jun 2015 |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
|
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Capsigen | Vancouver, WA | AAV Vectors |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| , | Merged with ABX-CRO | |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| Nycomed | , | Acquired by Takeda 2011 |
| Valneva | Lyon, France | Antibody Discovery |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| DDL | Edison, NJ | Device Testing |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| ConquerX | , | Dissolved Jun 2021 |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Veracyte | South SF, CA | Cytology Diagnostics |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| , | Website down May 2025 - Dec 2025 | |
| Zenosense | , | No website, shell company Nov 2020 |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| MicroStem | , | Gone Jun 2017 |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Zyomyx | , | Closed as of 2014 |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Imstem Biotechnology | , | Website gone May 2021 |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
|
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Lupin | Goa, India | Generics |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| , | Website down Apr 2026 - Aug 2026 | |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
|
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Stada | Vršac, Serbia | Generics |
| FIT Biotech | , | Bankrupt Feb 2019 |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Cognis Corp | , | Acquired by BASF 2010 |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Abpro | Burlington, MA | Antibodies |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| , | Website down Jan 2026 - May 2026 | |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Panaxia | Lod, Israel | Medical Cannabis |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| , | Website down Jan 2026 - May 2026 | |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Acologix | , | Closed Aug 2011 |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Vision Genomics | , | Website Gone, Jul 2016 |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Leukosight | , | Gone, website is online pharmacy now |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Pharmos | , | Gone |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| , | Renamed Kyntra Bio, Jan 2026 | |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Cure Foreward | , | Services suspended, May 2017 |
| Impulse Dynamics | Marlton, NJ | Implantable Heart Failure Devices |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| Redwood City, CA | Merged with Kira Pharmaceuticals, Jul 2026 | |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| Lifebit | London, UK | Genetic Data Analysis |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Lavipharm | Paris, France | Small molecules |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| DiagnoCure | , | Liquidated, Apr 2016 |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
|
Redmond, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| Macleods Pharmaceuticals | Himachal Pradesh, India | Generics |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Enovalife | Paris, France | Biometrics and medical writing services |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| , | Acquired by Sebia, Sep 2024 | |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Outset Medical | San Jose, CA | Dialysis Device |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Inventa Biosciences | , | Not Active |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| RecomGenex | , | Renamed TargetEx Biosciences |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| InnovAAVector | Pozzuoli, Italy | AAV CDMO |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| BianoGMP | Gera, Germany | Oligonucleotides |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Stelvio Oncology | , | Gone late 2019 |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| Catalyz | , | Gone |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Seeker Biologics | , | Shut down May 2023 |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| Revotek | , | Website down May 2023 - Sep 2023 |
| ChemPacific | Baltimore, MD | Chemicals |
| Accellacare | Salisbury, NC | Clinical Research |
| Tecomet | Lansing, MI | Forging, CNC Machining, EDM, Finishing, Special Processes |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Regenerative Sciences | , | Took on Regenexx product name |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| Heraeus Medical | Kolkata, India | Medical Devices |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| OvaGene Oncology | , | Gone Feb 2020 |
| Retroject | , | Seems gone |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Novartis | Emeryville, CA | Diagnostics |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| , | Website down Mar 2026 - Aug 2026 | |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| , | Renamed Esco Healthcare, Jul 2026 | |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Recensa Therapeutics | , | Only employee gone 2018 |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| InteKrin | , | Owned by Coherus Biosciences |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Telo Genomics | Toronto, ON | Diagnostics |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Salvat | Barcelona, Spain | Small Molecules |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Curefaktor Pharmaceuticals | , | Website Gone |
| AssureRx | , | Renamed Assurex Health |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| , | Website redirecting to Tedan Surgical Systems, Jul 2026 | |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| , | Website gone Feb 2026 - Jun 2026 | |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Keenova | Malvern, PA | Small Molecules |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| COR Clinical Research | , | Shut down after owner passed |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| Amakem | , | Website gone Dec 2015 |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| AbBaltis | Kent, UK | Plasmas & Sera |
| Bach Pharma | , | Shut down late 2023 |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Greenstone Biosciences | Palo Alto, CA | |
| Yao Pharma | Chongqing, China | APIs, Generics |
| SulfaGENIX | , | Website gone, Jan 2019 |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| , | Renamed Transcend, Feb 2022 | |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Institute for Drug Discovery | , | Gone |
|
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Vrata Therapeutics | Cambridge, | |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Delpharm | Huningue, France | Contract Manufacturing |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| , | No news 2016 - Sep 2025 | |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| Excelimmune | , | Closed Jul 2016 |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| Aimsn Medical | Beijing, China | Devices, Implants, First Aid |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Serentrix | , | Seems gone Apr 2022 |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| , | Liquidating, Sep 2025 | |
| Cytiva | Freiburg, Germany | Medical Devices |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Helix | San Mateo , CA | Genetic Testing |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| , | Website down Apr 2026 - Aug 2026 | |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Apath | , | No website update since 2014, Feb 2023 |
| GemacBio | , | Renamed PolyNeuroS |
|
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Esoterix | , | Bought by LabCorp, May 2005 |
| MetaStat | , | Website gone May 2019; Shell Company |
| Gerard Biotech | , | Lab supplies, seems defunct |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| , | Acquired by Eli Lilly, Jul 2026, $3.25B + $3.75M milestones | |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| , | LI gone Jul 2026; Website down May 2026 - Jul 2026 | |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| Oncofactor | , | Gone 2016 |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Pharos iBT | , | aka Pharos iBio |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| ORIG3N | , | Renamed Seaport Diagnostics |
| , | ||
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| CompleGen | , | Shut down Aug 2021 |
| , | Acquired by Biomarin, Jul 2025, $270M | |
|
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| , | Website down Dec 2025 - Apr 2026 | |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Laborie | Portsmouth, NH | Medical Devices |
| Summit Therapeutics | Miami, FL | Utrophin modulation technology |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Createrna Science | Shanghai, China | Small Molecules |
| AtCor Medical | , | Now part of CardieX |
| NeuTec Pharma | , | Shut down 2010 |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| GenEscence | , | Gone Jul 2013 |
| Palmaz Scientific | , | Bankrupt, 2016 |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| neoSurgical | , | Shut down 2017 |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| , | Acquired by Quest, Jun 2023, $450M; aka Haystack Oncology | |
| alphaSyx Therapeutics | , | Gone |
| Genomas | , | Website gone May 2020 |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| Bausch Health | Laval, QC | Small Molecules |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| Compugen | San Francisco, CA | Biologics |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Nile Therapeutics | , | Merged with Capricor |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
|
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Website down Jul 2025 - Dec 2025 | |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Azad Pharma | Montreal, QC | APIs, generics |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| GenEndeavor | Hayward, CA | Diagnostics |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
|
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Core Biomedicine | Allston, MA | |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| Guardion Health Sciences | , | Shut down |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| , | Acquired by Bio-Techne, Apr 2021, $215M + $105M milestones | |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| Endogenx | , | Website Gone Dec 2013 |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| , | Website down Aug 2026; LI gone Nov 2023 | |
| , | Website down Dec 2025 - Jun 2026 | |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| , | No website updates since 2013 as of Dec 2025 | |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| , | Website down Jun 2025 - Dec 2025 | |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Lectus Therapeutics | , | Sold off product |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Synovex | , | Renamed Adheron Therapeutics |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| AbX Biologics | , | Renamed Abveris |
| Arbovax | , | Gone |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Calzada | , | Renamed Polynovo |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| Ana-Gen Technologies | , | Gone post 2001 |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Genfit | Loos, France | Drug Discovery |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| DNASTAR | Madison, WI | Molecular Biology Software |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| Symbollon | , | Gone |
| CMP Therapeutics | , | Dissolved, May 2015 |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Ovation.io | Portland, ME | LIMS |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Verus Pharmaceuticals | , | Dissolved |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| , | Renamed ScionxBio | |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| , | Website down Feb 2026 - Jul 2026 | |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| 3DBiopsy | , | Renamed Triopsy |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Otsuka | Tokushima, Japan | Small Molecules |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| , | Acquired by OraSure Technologies, Dec 2024, $25M | |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| , | Acquired by Takara Bio, Jan 2025 | |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| Mednoxa | , | Website gone Jan 2020 |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Starpharma | Abbotsford, Australia | Antibacterial |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| ProteoVec | , | Website gone Jul 2015 |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| PnuVax | , | No news 2017 - Aug 2024 |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| Bioserv America | , | Shut down Aug 2024 |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| ArunA Biomedical | , | |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| , | Pivoted to crypto Jan 2026 | |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Apic Bio | , | Shut down Jan 2024 |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| Boca Pharmacal | , | Bought by Qualitest |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Delta-Vir | , | Website down Mar 2023 |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| RegeneraTEch | , | Renamed Regencor |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Alltrna | Cambridge, MA | tRNA therapies |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Gilead | Mississauga, ON | Small Molecules |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Typharm | Norwich, UK | Generics |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Narus Development Solutions | , | Gone |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
|
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Kesios Therapeutics | , | Closed down according to investors |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Helsinn | Iselin, NJ | Small Molecules |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| MicroPort | Arlington, TN | Medical Devices |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| Hemanext | Avon, MA | Transfusion Technologies |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Avalyn Pharmaceuticals | Boston, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| Axbio | Santa Clara, CA | Biochips |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Synergistix | Sunrise, FL | CRM software |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| LianBio | , | Winding down Feb 2024, came back Jul 2026 as LianMedical |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| NeuroWave Systems | Beachwood, OH | EEG |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Advanced Vision Science | , | |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| , | Website gone Feb 2026 - Apr 2026 | |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| Doloromics | , | Shut down Mar 2025 |
|
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| White Biotech Solutions | , | Shut Down 2019 |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| , | Shut down May 2025 | |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| SERB Pharmaceuticals | West Conshohocken, PA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Hybrigenics | , | Renamed ATON |
| EPD Biotherapeutics | , | |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| JCL Bioassay | , | Renamed CMIC |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| , | Website down Aug 2025 - Jan 2026 | |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| Novogene | Beijing, China | Genomic Services |
| Cogentis Therapeutics | , | No news 2017-2023 |
| InnoCare | Nanjing, China | Cancer Treatments |
| Terumo Medical | Elkton, MD | Medical Devices |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Cytoskeleton | Denver, CO | Research Products |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| Diosynth | , | Bought by Organon, Jan 2005 |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| Immagene | , | Renamed Flindr Therapeutics |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Synlab | Munich, Germany | Clinical Lab Services |
| Ambu | Ballerup, Denmark | Medical Devices |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| Newormics | , | Renamed vivoVerse, late 2022 |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| Alife | San Francisco, CA | AI-powered IVF |
| Delpharm | Lille, France | Contract Manufacturing |
| , | Website down Feb 2026 - Aug 2026 | |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Nusano | Valencia, CA | Radioisotopes |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Molecular Loop | Woburn, MA | NGS Technology |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| , | No news 2018 - Sep 2025 | |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| PMG Research | , | Now Acellacare |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Bio-Detail | , | Website gone Feb 2023 |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Ketal Biomedical | , | Gone |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| Noscira | , | Liquidated |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Micell Technologies | , | Seems shut down 2019 |
| Techne | , | Part of R&D Systems |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Refeyn | Oxford , UK | Mass Photometry |
| Almac | Souderton, PA | Pharmaceutical Services |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| Lung Bioengineering | , | Part of United Therapeutics |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Divide and Conquer | , | Website gone Mar 2024 |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Solexa | , | Merged with Illumina 2006 |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Novalar | , | Licensing agreement, essentially gone |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
|
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
|
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| , | Acquired by Healx, Sep 2025 | |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| Erba MDX | , | Website gone Aug 2019 |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| , | Website down Feb 2026 - Jul 2026 | |
| ProPharma Group | Washington, DC | Consulting |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
|
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| SR Pharma | , | Now Silence Therapeutics |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Opis Research | Desio, Italy | Clinical Research |
| Lumanity | London, UK | Consulting |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Baxter | Alliston, ON | Medication Delivery |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| Brighton Biotech | , | Only employee is an accountant |
| Summit Therapeutics | Princeton, NJ | Utrophin modulation technology |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Biolab | São Paulo, Brazil | Small Molecules |
| Network Bio | Palo Alto, CA | Disease-specific AI models from human biological data |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Sanofi | Paris, France | Small Molecules |
| SmartCells | , | Bought by Merck Dec 2010 |
| Axikin Pharmaceuticals | , | Closed per Google |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| Viravaxx | , | |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| VistaMed | , | |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| , | Website taken over, Jul 2026 | |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| , | Pivoted to food, Feb 2026 | |
| Robeauté | Paris, France | Neurosurgical Robotics |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| , | Website down Apr 2026 - Aug 2026 | |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| ResVerlogiX | San Francisco, CA | Small Molecules |
|
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Libra Clinical Research Associates | , | Gone |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Gensia Sicor | , | Renamed Sicor |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Velomedix | , | Shut down 2014 |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
|
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| miR Scientific | , | Renamed miRNA Scientific |
|
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Macleods Pharmaceuticals | Mumbai, India | Generics |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Precise Bio | , | Gone 2023 |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| , | Renamed Stelexis BioSciences | |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| Vernacare | Maple, ON | Surgical Devices |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Endo Tools Therapeutics | Gosselies, Belgium | Triangulation platform for tissue piercing |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Affymax | , | Dissolved 2014 |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
|
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Kembiotix | , | No info, Aug 2022 |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Alfasigma | Bologna, Italy | Small Molecules? |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| X7 Research | , | Website hijacked Feb 2025 |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Ikotech | , | Closed Dec 2015 |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| IDRx | , | Acquired by GSK, Feb 2025 |
| DNA Worldwide | Frome, UK | DNA Testing |
| BioCydex | , | No info 2019 - Mar 2025 |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| , | Liquidating Jan 2026 | |
| Straumann | Andover, MA | Dental Implants and Regeneration |
|
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Genopis | , | Acquired by Wacker Feb 2021 |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| Simbex | Lebanon, NH | Biomechanical devices |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Genestack | Cambridge, UK | Genomics operating system |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| , | Seems gone, Feb 2026 | |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| Grunenthal | Aachen, Germany | Small molecules |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| , | No news 2019 - Sep 2025 | |
| Axonia Medical | , | Gone 2015 |
| , | Website down Dec 2025 - Jun 2026 | |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Vivex Biologics | Atlanta, GA | Tissues |
|
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| CorTechs Labs | , | Renamed Cortechs.ai |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| Inventprise | Redmond, WA | Vaccines |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
|
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| , | Acquired by Stryker, Oct 2024 | |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
|
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Ankon Technologies | Wuhan, China | Medical Devices |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| MabQuest | , | No website Dec 2018 - May 2023 |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| , | Looks like 1 employee, no news 2017-Aug 2026 | |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| TR Biosurgical | , | Website Taken Over |
|
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
|
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| BEAT BioTherapeutics | , | Closed 2017 |
|
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Neuro Bio | Oxford, UK | T14 Blocker |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| PhytoMedical | , | Apparently Gone |
| TumorGen | San Diego, CA | Cancer Treatments |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Soin Neuroscience | , | Seems like one guy, sold tech Jul 2026 |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| MaxThera | , | Shut Down Dec 2011 |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| Clearbridge Biomedics | , | Renamed Biolidics |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| CORONIS | Athens, Greece | Clinical Studies |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Meristem Therapeutics | , | Defunct |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
|
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Mabqi | Grabels, France | Antibody Discovery |
| Encorium | , | Bankrupt |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| NeuroSearch | , | Wound down 2012 |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| , | Website down Feb 2026 - Jul 2026 | |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| Celtaxsys | , | No longer active, Aug 2020 |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Brain Vision | Morrisville, NC | EEG Systems |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| Yicura | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Createrna Science | Wuhan, China | Small Molecules |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| Spiden | , | Renamed Liom, Jul 2024 |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Trudell Medical | London, ON | Inhalation Devices |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Cytiva | Marlborough, MA | Medical Devices |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| Bio Processing | , | Bought by Bio-rad |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Sebra | Tucson, AZ | Tube Sealer |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| Zai Lab | Cambridge, MA | Small Molecules |
| Alfama | , | Merged into Proterris, May 2017 |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Mardil Medical | , | Website gone Feb 2021 |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Conformis | , | |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| , | Website down Apr 2026 - Aug 2026 | |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| Westat | Rockville, MD | Clinical trial design, management, services |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Photonion | Schwerin, Germany | Analytical Equipment |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| Endomag | Cambridge, UK | Biopsy Tracer |
| , | Acquired by Besins Healthcare, Jun 2026 | |
| Vascular Genesis | , | Website gone Aug 2022 |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| , | Website hijacked Oct 2025 | |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| , | Website down Jun 2025 - Dec 2025 | |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Veravas | Oakdale, MN | Diagnostics |
| , | Website down Aug 2025 - Jan 2026 | |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| BioWa | , | Part of Kyowa Kirin Group |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Piramal | Turbhe, India | CDMO |
| , | LI gone Jul 2026; Website down Jun 2026 - Aug 2026 | |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Avenge Bio | , | Shut Down Jul 2024 |
| Primera Biosystems | , | Now PrimeraDx |
| Bionorica | Neumarkt, Germany | Plant-derived Medicines |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Medicure | Princeton, NJ | Small Molecule |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Sonosine | Kidlington, UK | Medical Imaging |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
|
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
|
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| , | Website down Jul 2025 - Jan 2026 | |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| Regenica Biosciences | , | Gone Nov 2020 |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Coordination Therapeutics | , | Not Active |
| Abpro | Lexington, MA | Antibodies |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Healogix | Doylestown, PA | Consulting |
| , | No news 2019 - Jul 2026 | |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| NanoVector | , | Gone 2019 |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| Synakis | Toronto, ON | Ocular Delivery Hydrogel |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Medochemie | Limassol, Cyprus | Generics |
| Biodel | , | Merged with Albireo, Oct 2016 |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Hybrigenics Services | , | Renamed ATON Group |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| , | Website down Jan 2026 - Mar 2026 | |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Attenuon | , | Now Tactic |
| Roche | Pleasanton, CA | Diagnostics |
| , | Website down Jan 2026 - May 2026 | |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Aves Labs | , | Now part of Antibodies Inc |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| Triage Wireless | , | Now named Sotera Wireless |
| MacroPore | , | Gone |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| SiliCycle | Québec, QC | Separation Technologies |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| CPI Global | , | Website gone Jun 2020 |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Glialogix | , | Gone Nov 2017 |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| , | Website down Jan 2026 - May 2026 | |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| TidalSense | Cambridge, UK | Respiratory Diagnostics Platform |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Microphage | , | Bankrupt Jun 2013 |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| AuraSense Therapeutics | , | Renamed Exicure |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| , | Website down Nov 2025 - Dec 2025 | |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Ergomed | Frankfurt, Germany | Clinical Research |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| , | Part of ICE Pharma | |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| LivaNova | London, UK | Nerve stimulation therapy |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| Ergomed | Mumbai, India | Clinical Research |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Prognosys Bioscience | , | 10 years in stealth mode |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| NeuMedics | , | Website taken over by massager sales |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Journey Colab | , | Shut down Jan 2025 |
| RegeneMed | , | No longer active in CA as of 2014 |
| Valor Biotechnology | , | Renamed Roivant |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Ataia Medical | , | Website taken over Jan 2024 |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Lyman Biopharma Consulting | , | Switched to writing |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| Azopharma | , | Bankrupt, Apr 2010 |
| , | No news 2019 - Aug 2026; Residential Address, Jun 2025 | |
| Integer | Alden, NY | Medical & Surgical Devices |
| Alsinova | Boulogne-Billancourt, France | Clinical & Regulatory Consulting |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| Berlex | , | Now Bayer |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| M3 Wake Research | Encino, CA | Clinical Research |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| UMN Pharma | , | Liquidating Apr 2025 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Cala Health | San Mateo, CA | Neurological Device |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Nano Oncology | , | Gone |
| , | Now part of BioVendor | |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| , | Acquired by Xoma, Sep 2025 | |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| FineHeart | Pessac, France | Heart Failure Device |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Applied Molecular Genetics | , | Renamed Amgen |
| Nodality | , | Gone |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| Bioenza | , | Website gone Sep 2017 |
| Vessel Biosciences | , | Shut down Mar 2023 |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| , | Assets Acquired by Synaptiq Therapeutics, Jul 2026 | |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| Ocis Biotechnology | , | |
| , | Renamed BTgen Bio, May 2026 | |
| , | Renamed Grey Matters Health, Apr 2026 | |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Provecs Medical | , | Gone Nov 2019 |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| VersaPharm | , | |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Hemay Pharmaceutical | Tianjin, China | |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Pevion Biotech | , | Gone, 2-19-14 |
| simAbs | Diepenbeek, Belgium | Fast, flexible and cost-effective biologics development and GMP manufacturing |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| F2G | Cheshire, UK | Antifungals |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| SARcode | , | Bought by Shire Mar 2013 |
| Hasten Pharma | Hefei, China | Small Molecules |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Evidera | , | Acquired by PPD, 2016 |
| , | Acquired by Cambridge Bioscience, Feb 2026 | |
| , | Renamed ExGen Dx, Jul 2025 | |
| Moximed | Fremont, CA | Joint treatment |
| Bio-ops | , | Now SVA |
| Roslin Cells | , | Renamed RoslinCT |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| , | Website down Dec 2025 - Apr 2026 | |
| Coldstream Laboratories | , | Bought by Piramal |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| Getinge | Rastatt, Germany | Medical Technology |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Beardsworth | , | Bought by TFS International 2013 |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| vTv Therapeutics | High Point, NC | Small molecules |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| Centocor | , | Renamed Janssen Biotech |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| MikrobEX | , | Renamed Rebiotix |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
|
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Evopoint Biosciences | Waltham, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| Bestat Pharmaservices | Taipei, Taiwan | Clinical Consulting |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Cato Research | , | Renamed CATO-SMS |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
|
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| , | Website down Jan 2026 - May 2026 | |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| Ebewe Pharma | , | Now Sandoz |
| , | Filings late Jun 2025 | |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| , | Acquired by Lonza, Apr 2017 | |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| Boehringer Ingelheim | Vienna, Austria | Small Molecules, Biologics, CDMO |
| Boston Scientific | Valencia, CA | Medical Devices |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| Cytiva | Tokyo, Japan | Medical Devices |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| , | Acquired by Azenta, Feb 2023 | |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Ionpath | , | Shut down Feb 2025 |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Abbott | Des Plaines, IL | Diagnostics |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| , | Renamed Helyx Industries | |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Semafore Pharmaceuticals | , | Gone? |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| , | Acquired by Epitype, Oct 2025 | |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| Quanticate | Bangalore, India | Clinical Research |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| E3X Bio | , | Shut Down Mar 2019 |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Medica | , | Gone before 2019 |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Averion | , | Now Aptiv |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Cambrian Bio | New York, NY | Small Molecules |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| TargeGen | , | Bought by Sanofi 2010 |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| algorithmRx | , | Now Venebio |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| VitamFero | , | Website gone Aug 2018 |
| Diverse Genomics | , | Website gone Jul 2020 |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Analiza | Cleveland, OH | Physicochemical Services |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Selten Pharma | , | Gone 2017 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Thyritope Biosciences | , | Closed Oct 2016 |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| REV Clinical | Bakersfield, CA | Clinical Trials |
|
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Roche | Tucson, AZ | Diagnostics |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
|
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Generex Biotechnology | , | Website gone Feb 2024 |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Clinical Scientist Group | , | Website gone, employee gone |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| K2M | , | Acquired by Stryker, Nov 2018 |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Sirius Genomics | , | Gone |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| Gamma Therapeutics | , | Gone |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Mott | Farmington, CT | HPLC system components, Filtration |
| Alverix | , | Acquired by BD, Jan 2014 |
| Pharmaron | Xi'an, China | R&D Services |
| Diamed | , | Bought by Bio-rad |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Groove Biopharma | , | Gone 2015 |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Getinge | Växjö, Sweden | Medical Technology |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Apcer Life Sciences | London, UK | Consultants |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| MicroPort | Shanghai, China | Medical Devices |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| Conkwest | , | Website gone Dec 2015 |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Novitium Pharma | East Windsor, NJ | Generics |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| , | Website down Nov 2025 - Apr 2026 | |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| CRIO | Boston, MA | eClinical Software |
| ions.bio | Planegg, Germany | Biomarkers |
| Novosis | , | Acquired by Acino, 2006 |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| Bone's Technology | Shenzhen, China | Bone Density Analysis, Surgical Planning |
| , | Website down Jul 2025 - Jan 2026 | |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Epana Bio | Berkeley, CA | Autoimmune Treatments |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Raytone Bio | , | |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Gen-probe | , | Acquired by Hologic 2012 |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Artivila Biopharma | Shenzhen, China | Artificial Intelligence-Driven Drug Discovery |
| Noeledge | , | Shut down Jul 2024 |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| , | Website down Feb 2026 - Jul 2026 | |
| Pall | Port Washington, NY | Filtration |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| OmniBiome Therapeutics | , | Gone 2014? |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| , | Website down Feb 2026 - Jul 2026 | |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| ICN Pharmaceuticals | , | Now Valeant |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| CorWave | Clichy, France | Blood Pumps |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Healx | Cambridge, UK | AI Drug Discovery |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
|
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
|
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| MabCo | , | Renamed Agenix |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Scientia Advisors | , | Website gone Jul 2015 |
| Amplifold | , | DNA origami nanotechnology |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Chaperone Therapeutics | , | Gone 2019 |
| ReSync Bio | , | Acquired by Benchling 2025 |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| , | Shut down Jun 2026 | |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| STB Lifesaving Technologies | , | Website gone |
| Indero | Montréal, QC | Dermatology Clinical Research |
| Advangen | , | Acquired by Cellmid, May 2013 |
| , | Website taken over May 2026 - Jun 2026 | |
| Mattson Jack | , | Now Kantar Health 2009 |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Anfiro | , | Shut down Dec 2019 |
| EsbaTech | , | Bought by Alcan |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| UniteLabs | , | Shut Down |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Carrington Labs | , | Changed Name to DelSite |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| , | Gone Mar 2024 | |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Diatos | , | No website, founded 1999 |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| , | Renamed Axiom Biosciences, Jun 2026 | |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Allometra | , | Gone |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| Dorphan | , | Shut down so owner could spend more time skiing |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Theramex | London, UK | Women's Health |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| NeuroPharm | , | Liquidated 2010 |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| Iproteos | , | Products now with Accure Therapeutics |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Hutchmed | Hong Kong, China | Oral drugs |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Gentegra | , | Part of IntegenX |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| , | Flash website Jul 2026; LI gone Jul 2026 | |
| Gensignia | , | Website Gone, Aug 2017 |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
|
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| MiniMed | Northridge, CA | Diabetes Management |
| Pfizer | Surrey, UK | Consumer Healthcare |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| bioTHER | , | Gone |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| , | Part of SBO Hearing, Feb 2026 | |
| Ortho Development | Draper, UT | Ortho Implants |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| AlphaVax | , | No employees on LI. Not sure active |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| LifeSensors | , | Website hijacked Feb 2025 |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| Xact Medical | , | Website down Mar 2024 |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| NeoVista | , | Gone 2011 |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| Arxspan | , | Renamed SciY |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Cimple Biotechnology | Hong Kong, China | Rapid POC Diagnostics |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Medarex | , | Bought by BMS 2009 |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Texcell | Shanghai, China | Contract Research |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| , | Acquired by Certara, Oct 2024 | |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| STARLIMS | Hollywood, FL | LIMS |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| Streamline Scientific | Austin, TX | Molecular Technologies |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Telephus Medical | , | Now Telephus Biosciences |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Entelos | , | Bankrupt |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| Cambria Biosciences | , | Gone Feb 2008 |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
|
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| yuFlu | , | No website, no info Feb 2021 |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| AstraZeneca | New Haven, CT | Biologics |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Apollomics | Foster City, CA | Cancer medicines |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| , | Website down Jun 2025 - Dec 2025 | |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Islet Sciences | , | Gone |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| VastBiome | , | Renamed PragmaBiome |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Otsuka | Rockville, MD | Small Molecules |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| , | Acquired by Siegfried, Jan 2026; Bought by J&J, resold Jul 2016 | |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| Minimally Invasive Devices | , | Shut down |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Librede | , | Acquired by Lygos, Jan 2020 |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| Prochon Biotech | , | Acquired by Histogenics |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| Riverain Technologies | Miamisburg, OH | Imaging |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| , | Website down Mar 2026 - Aug 2026 | |
| Heraeus Medical | Dorado, PR | Medical Devices |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Medrobotics | , | Bankrupt Jun 2022 |
| , | Acquired by Kite, Aug 2025 | |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| CardioCanary | , | Founders gone. Doubt it's active |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| McGee Pharma | , | Merged with Pharmalex |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| XRlabs | Albacete, Spain | Surgical Intelligence, Visualization |
| Angex Pharmaceuticals | , | Gone 2018 |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Qynapse | Paris, France | Imaging Analysis |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| Evozyne | Chicago, IL | Protein Design Platform |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| Arraystar | Rockville, MD | Microarrays |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| EyeTel Imaging | , | Gone Jul 2015 |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| Bioclinica | , | Merged with ERT, 2021 |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| Curadigm | , | folded into Nanobiotix |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Kentucky Bioprocessing | , | Now Kbio |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Accellacare | Cary, NC | Clinical Research |
| , | Website down Mar 2026 - Jul 2026; LI gone Jul 2026 | |
| Sophiris Bio | , | Shut down May 2020 |
| DNAMx | , | Renamed Adela |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| , | Website down Jan 2026 - May 2026 | |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| nplex biosciences | , | Renamed Nomic Bio |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Gossamer Bio | San Diego, CA | Small Molecules |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Seneb Biosciences | , | Gone 2017 |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| , | Acquired by eurofins, Jun 2019 | |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Axplora | Shanghai, China | Purification Systems |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Santen | Osaka, Japan | Ophthalmics |
| CeQur | Luzern, Switzerland | Insulin pump |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| TaliaPharm | , | Website gone, Jan 2018 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Pfizer | Kalamazoo, MI | Manufacturing |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Cytopeia | , | Acquired by BD, May 2008 |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| Immunovaccine | , | Rebranded IMV, 2018 |
| , | Gone Aug 2026; LI gone Jul 2026; Website down May 2026 - Jul 2026 | |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| Modern Biosciences | , | Renamed Istisso |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Hematogenix | Tinley Park, IL | Pharma Services |
| Medrio | San Francisco, CA | Clinical Trial Software |
| XtalPi | Cambridge, MA | AI Drug Design |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Genyro | San Francisco, CA | DNA Construction Technology |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| Pentapharm | Basel, Switzerland | APIs |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Carver Biosciences | , | |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| BINEX | Seoul, Korea | Biologics CDMO |
| , | Renamed Ribonexus, Nov 2021 | |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Biohit | Helsinki, Finland | Diagnostics |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| , | ||
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| Steba Biotech | , | Renamed ImPact Biotech |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| VasoNova | , | Acquired by Teleflex Medical |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
|
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| Trine Pharmaceuticals | , | Closed 2008 |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| SeqRight | , | Acquired by GE Apr 2012 |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| Pfizer | Ringaskiddy, Ireland | API production |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| Virvio | , | Gone Feb 2020 |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| Cureport | Worcester, MA | Nanomedicines |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| LFB | Paris, France | Plasma derived drug products |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| Knopp Biosciences | , | |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| , | Now part of Exalta | |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| Mabcare Therapeutics | , | |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| MilliporeSigma | Madison, WI | Small Molecules |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| American Stem Cell | , | Changed name to Targazyme |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| , | Acquired by mining company; fka Anew Medical | |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| , | Website down May 2025 - Jan 2026 | |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| TearScience | , | Acquired by J&J, Nov 2017 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| MindRank | Shanghai, China | AI Drug Discovery |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Amp Orthopedics | , | Shut down, 2012 |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Website down Dec 2025 - Apr 2026 | |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| Nascent Biologics | , | Changed to Nascent Biotech |
| preclinics | Parma, Italy | Contract Research |
| PredxBio | Pittsburgh, PA | Image Analysis |
| Inference | Pune, India | Clinical Trial Services |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| BioNanomatrix | , | Renamed BioNano Genomics |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Eyetech | , | Website Gone 6-16-12 |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Mitokyne | , | Renamed Mitobridge |
| Ottobock | Vienna, Austria | Prosthetics |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Viral Genetics | , | Now VG Life Sciences |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| , | Subsumed into GSK, Jun 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Orange Biotech | Hong Kong, China | Microfluidic nucleic acid detection system empowered with CRISPR |
| , | Seems to have shut down mid 2025 | |
| Gilson | Middleton, WI | Lab Supplies |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| Acelyrin | , | Merged into Alumis, May 2025 |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| , | one page website ©2020 in Jul 2026 | |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| Claryx | Long Island, NY | Hospital Infection Management Platform |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Intrexon | , | Renamed Precigen |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| Anergis | , | Liquidating, Jan 2021 |
| , | Acquired by Biogen, Nov 2025, $85M; fka Alcyone Lifesciences | |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| Reserva | , | Renamed NeurMedix, 2016 |
| MSD | Leopardstown, Ireland | Small Molecules |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| InteguRx | , | Website taken over, Dec 2023 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| SanBio BV | Uden, Netherlands | Antibodies |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| , | Website down Nov 2025 - Apr 2026 | |
| Novotech | Sydney, Australia | Clinical Research |
| Deinove | , | Bankrupt Mar 2023 |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Dharma Therapeutics | , | Gone, 2013 |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| Getinge | Antalya, Turkey | Medical Technology |
| Nexus Genomics | , | Gone 2001 |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Biocodex | Gentilly, France | Microbiota Treatments |
| DDi | London, UK | Clinical Software |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Celerion | Zurich, Switzerland | Clinical Research |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Alliances Catalyst | , | Liquidated |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Perceptive | Nottingham, UK | Medical Imaging |
| Tasso | Seattle, WA | Blood-collection products |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| TRIA Bioscience | , | Shut down Aug 2021 |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Exalta | Bethlehem, PA | Orthopedic Devices |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| Able Labs | , | big FDA trouble, gone |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Innogenix | Amityville, NY | Generics |
| Moon Surgical | Paris, France | Robotic Surgery System |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| Serentis | , | Website Gone |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
|
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| GeneSeek | , | Bought by Neogen |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| Clinilabs | Eatontown, NJ | Clinical Research |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| Indocruit | , | Gone |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| BioTheryX | San Diego, CA | Small Molecules |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| , | Website down Jul 2025 - Dec 2025 | |
| Voitheia Bioscience | , | |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| , | Acquired by Merck, May 2026, $6.67B | |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Baxter | Singapore, Singapore | Medication Delivery |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Emulate | Boston, MA | Organs-on-chips |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Lotte Biologics | East Syracuse, NY | Biologics CDMO |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Tecomet | Kenosha, WI | CNC Machining, EDM, Finishing, Special Processes, Orthopedics, SET, Advanced Surgical |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| AdipoGenix | , | Gone Jun 2012 |
| Epic Sciences | , | Shut down May 2025 |
| Sequoia Pharmaceuticals | , | Folded |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Idience | Seoul, Korea | Cancer Therapies |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| Celemics | , | Gone Jul 2018 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Biocoat | Horsham, PA | Medical Device Coatings |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| Vadovations | , | No info. 2012 SBIR grant |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Heritage Pharmaceuticals | , | Part of Emcure |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| Gerinda Therapeutics | , | Gone 2009 |
| Recon Therapeutics | , | Shut down Jun 2017 |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Dendritix | , | Renamed Argos Therapeutics |
| NeuMed | , | Website four years since update, no employees on LI |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Activated Cell Therapy | , | Changed name to Dendreon |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
|
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Tychan | , | Liquidated early 2022 |
| Doctor Pack | Bangalore, India | Packaging |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| Blu Biotech | , | Website down May 2023, CEO gone |
| PRI Research | , | Renamed Wake Clinical |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| GeneDx | Stamford, CT | Genetic Data |
|
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Venclose | , | Acquired by BD, Dec 2021 |
| , | Website down Mar 2026 - Jul 2026, LI gone Jul 2026 | |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| PACT Pharma | , | Shut down Sep 2023 |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| Automata | London, UK | Lab workflow automation platform |
| Vivamer | , | Shut down, Jul 2015 |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| , | Shut down Aug 2025 | |
| Fortrea | Durham, NC | Clinical Research |
| NeuroVia | , | Shut down 2019 |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| Chromocyte | , | |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| Eurogentec | Seraing, Belgium | Biologics |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| SE3D | , | Renamed Seed Therapeutics |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Metrohm | Houston, TX | Lab Data Management Software |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| Adaptix | Oxford, UK | Medical imaging |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Hoth Therapeutics | New York, NY | Small Molecules |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| Recida Therapeutics | , | |
|
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Abgent | , | Renamed Abcepta, 2019 |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Novonesis | Beijing, China | Enzymes |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| Cydan Development | , | Shut down Sep 2021 |
| EndoSphere | , | Gone pre-2011 |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| Getinge | Merrimack, NH | Medical Technology |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| , | Website down Mar 2026 - Aug 2026 | |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Trimeris | , | Merged with Synageva |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Eos Biosciences | , | Shut down Oct 2020 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| , | Website down Aug 2025 - Jan 2026 | |
| , | Acquired by Genesis Biotechnology Group, Mar 2017 | |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Genmab | Utrecht, Netherlands | Biologics |
| Healionics | Seattle, WA | Biomaterials for devices |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Endocare | , | Website down Jan 2021 - May 2021 |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| Maccine | , | Gone |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Calibrant | , | Closed |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| , | Website down Mar 2026 - Aug 2026 | |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| Corza Medical | Shanghai, China | Surgical Devices |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| Valitor | Berkeley, CA | Protein therapeutics |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Anaheim Clinical Trials | , | Now CenExelACT |
| Acidophil | , | Gone late 2022 |
| Leading Pharma | Fairfield, NJ | Generics |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| , | Renamed Create Medicines, Oct 2025 | |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
|
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Echo | San Diego, CA | Microscopy |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| , | ||
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Novotech | Bangkok, Thailand | Clinical Research |
| Accelrys | , | Bought by Dassault, 2014 |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| AmCell Biosciences | , | Website gone Apr 2021 |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| CMD Bioscience | , | Closed, 2015 |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| CMC Biologics | , | Now part of AGC Biologics |
| ImmuVen | , | Website gone, Dec 2015 |
| Amerging Biotechnolgies | Mohali, India | Bioprocess Equipment |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Apieron | , | Shut down, May 2010 |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| , | Website down Oct 2025 - Jan 2026 | |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Sanofi | Frankfurt, Germany | Small Molecules |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| PegaOne | , | Centessa Company |
| , | Website down Aug 2025 - Jan 2026 | |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Navinta | Ewing, NJ | Generics |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| , | Website down Sep 2025 - Dec 2025 | |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Cell Genesys | , | Merged with BioSante |
| Ekteino | , | Closed, Dec 2016 |
| , | No business filings Feb 2014 - Jul 2026 | |
|
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| Endovasc | , | Bankrupt 2008 |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| RxCelerate | Cambridge, UK | Contract Services |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| Gameto | New York, NY | Female Fertility Extension |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Akceli | , | Shut down, Sep 2004 |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Silence Therapeutics | Berlin, Germany | RNAi |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Asarina Pharma | , | Winding down Jul 2024 |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| CG Therapeutics | , | Dissolved Jul 2013 |
| BiOM | , | Now BionX Medical |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| Vyriad | Rochester, MN | Immunovirotherapy |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Sebia | Lisses, France | Electrophoresis |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Onorach | Dundee, UK | Clinical Trial Management |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Gilead | Edmonton, AB | Small Molecules |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Exelixis | Alameda, CA | Small Molecules |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Prescos | , | Shut down Feb 2014 |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
|
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Texcell | Frederick, MD | Contract Research |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| Naveris | Waltham, MA | Cancer Diagnostic |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| PL Developments | , | Parts of website taken over |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| Nabla Bio | Cambridge, MA | Antibody Design |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
|
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| , | Merged with Tecomet, Jan 2026 | |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| Imeka | Sherbrooke, QC | Neuroimaging |
| In Veritas Medical Diagnostics | , | Shell company |
| Xcelthera | , | Shut down, Apr 2021 |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Rhythm Health | , | Renamed Motus Therapeutics |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
|
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Kar Bioanalytical | , | Seem gone |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Alchemia | , | Gone, late 2017 |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| Dirui Industrial | Changchun, China | Automated Assays |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| Lupin | Mumbai, India | Generics |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| MabSpace Biosciences | , | Renamed Transcenta |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Lian Medical | Beijing, China | Medical Devices |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| , | Acquired by Ensysce Biosciences, Aug 2026 | |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
|
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Assay Designs | , | Now Enzo Life Sciences |
| BioArra | , | Bought by VWR Nov 2016 |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
|
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| SJ Pharma | , | Website gone, Nov 2018 |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| , | Acquired by Lonza, Jun 2023 | |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| TRPblue | , | Shut down Dec 2023 |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| , | Acquired by DEC Group 2021 | |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
|
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Osivax | Lyon, France | Universal Flu Vaccine |
| , | Renamed Nexalis Therapeutics, Jan 2026 | |
| Saniona | Glostrup, Denmark | Small Molecules |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| , | Acquired by Teva, Jun 2026, $700M | |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| MeDiNova Research | , | Now part of Accelacare |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| , | Renamed PKx Bio, 2026 | |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
|
Neuried, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| , | Website down Oct 2025 - Feb 2026 | |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| SYNkinase | , | Shut down |
| C/M/C Biologics | , | Now CMC Biologics |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Heragen | , | Gone |
|
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| , | Acquired by Insphero, Nov 2025 | |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| Genstruct | , | Now Selventa |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Panther Orthopedics | , | Shut down Dec 2022 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Biomatters | , | Renamed Geneious |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Cerimon Pharmaceuticals | , | Gone |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Premier Biomedical | , | Pivoted out of life science |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| , | Shut down Oct 2025 | |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments, CMO |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| , | Renamed Fareon, Feb 2025 | |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| , | Renamed ElisiGen, Dec 2025 | |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| Active Implants | , | Renamed NUsurface |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| Xencor | San Diego, CA | Antibody Discovery |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Alkermes | Waltham, MA | Small Molecules |
| Clina Research | , | Website gone Jul 2023 |
| Creative Bioinformatics Consultants | , | Gone |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| Zeto | Raleigh, NC | Dry Electrode EEG System |
| , | Website down Feb 2026 - Jul 2026 | |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Sixal | , | SBIR, Presumed defunct |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| , | Acquired by Esperion, Apr 2026 | |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| XW Laboratories | , | Renamed XWPharma |
| , | Website down Aug 2025 - Jan 2026 | |
| Ribomic | Tokyo , Japan | Aptamers |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| PhotoSonix Medical | , | Now a licensing outift |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
|
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Java Clinical | , | Website gone Jun 2019 |
| Keenova | Bridgewater, NJ | Small Molecules |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| , | Website down Jun 2025 - Dec 2025 | |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Confer Health | , | Shut down 2021 |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| restor3d | Durham, NC | 3D printed implants and devices |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| , | Merged with Nova Biomedical | |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Agile EndoSurgery | , | Gone |
| Roche | Welwyn, UK | Small Molecules |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Salgomed | , | Shut down Apr 2022 |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Theranos | , | Dissolving, Sep 2018 |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Ergomed | Zagreb, Croatia | Clinical Research |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| , | Acquired by IQVIA | |
| QC Ware | Paris, France | Molecular Discovery Platform |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| MURO PHARM | , | Dissolved, May 2007 |
| , | Renamed THX Pharma, Sep 2025 | |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| CTG Pharma | , | Gone |
| , | Website down Nov 2025 - Apr 2026 | |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| , | Now a Genovis product/service, Jul 2026 | |
| Altheos | , | Closed |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| PluriSelect | El Cajon, CA | Cell Separation |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| Bolder Biotechnology | Boulder, CO | Biologics |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| Roche | Burgess Hill, UK | Diagnostics |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| Pinnaxis | Noida, India | Pharmacovigilance |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| Monroe Research | Monroe, NC | Clinical Trials |
| Adrenergics | , | Gone Sep 2017 |
| Origen Therapeutics | , | Gone |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| CLCbio | , | Acquired by Qiagen, 2013 |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Advansta | San Jose, CA | Protein characterization products |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| Vascular Biogenics | , | Now VBL Therapeutics |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| Best Vascular Novoste | , | Now Novoste |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| , | Website down Jan 2026 - May 2026 | |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Stada | Bad Vilbel, Germany | Generics |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| Formation Biologics | , | Rebranded as Forbius |
| Metrochem | Hyderabad , India | APIs |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Abiologics | Cambridge, MA | Synteins |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| VasoRx | San Diego, CA | RNA delivery |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Avenir Pharma | , | No longer active |
| Calyx Pharma | Mumbai, India | APIs |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| , | Renamed Iditarod Bio | |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
|
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Prime Biologics | , | Seems gone 2019 |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Obecure | , | Inactive, no info |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Therics | , | Acquired by Integra |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| D-Pharm | , | Website Gone, Aug 2016 |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Handa Pharmaceuticals | Tainan City, Taiwan | Specialty pharmaceutical development - generic and 505(b)(2) |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Norton Scientific | , | Website Gone, Oct 2014 |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Defyrus | , | Website gone Nov 2017 |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| X2 Pharma | , | Website Gone |
| Bioquanta | , | Gone 2013 |
| Luye Pharma | Shanghai, China | Small Molecules |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| , | Acquired by eurifins, Sep 2024 | |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
|
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| , | Website down Sep 2025 - Dec 2025 | |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Duality Biologics | Shanghai, China | ADCs |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| Vyaire Medical | , | Acquired by Trudell Medical, rebranded as Jaeger medical Nov 2024; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Analog Pharma | Princeton, NJ | Generics |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| , | Website down Jan 2026 - May 2026 | |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Altasciences | Overland Park, KS | Contract Research |
| Accellacare | Wilmington, NC | Clinical Research |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| , | Renamed AtaiBeckley | |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| Copley Scientific | Nottingham, UK | Test equipment |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Evocutis | , | Pivoted to investments |
| WideCELLS | , | Shut down Nov 2019 |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| , | Website down Sep 2025 - Dec 2025 | |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| , | Website down Jun 2025 - Oct 2025 | |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| Antisoma | , | Became investment company |
| Sensys Medical | , | Old company, no website, presumed defunct |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Acretia | , | Gone |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| MiRus | Marietta, GA | Spine Implants |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Pathway Genomics | , | Renamed OmeCare |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Convergen | , | |
| CONMED | Largo, FL | Surgical, Medical Devices |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Abselion | Cambridge, UK | Biologics Quantification |
| IDM Pharma | , | Acquired by Takeda |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Enesi Pharma | , | Renamed aVaxziPen |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| , | No news 2019 - Oct 2025 | |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| , | Main person has four other jobs, Dec 2025 | |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| AB Sciex | , | Renamed Sciex |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| Tecomet | Wilmington, MA | EDM, FPI, Passivation, Ultrasonics, Forging |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Geneffects | , | Shut down Feb 2020 |
|
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Iconovo | Lund, Sweden | Inhalation Technology |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| IGF Oncology | , | Shut down 2022 |
| Purely Proteins | , | All employees gone, no info |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| , | Website down Oct 2025 - Jan 2026 | |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Coating Place | Verona, WI | Drug Delivery Services |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Accellacare | Raleigh, NC | Clinical Research |
| Alkermes | Wilmington, OH | Small Molecules |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| Biotox Sciences | , | Renamed BTS Research |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Crown Bioscience | Taicang, China | Drug Development |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Progyny | New York, NY | IVF products |
|
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| IntelligentMDx | , | Shut down Feb 2015 |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Baxter | Deerfield, IL | Medication Delivery |
| SIRGA Advanced Biopharma | , | Appears defunct |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Borean Pharma | , | Gone |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| AMDL | , | Now Radient Pharmaceuticals |
| Luvak Lab | , | Dissolved 2013 |
| AlphaGenix | , | Gone 2014 |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Vesper Medical | Wayne, PA | Venous Stent |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| United Neuroscience | , | Renamed Vaxxinity |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| , | Renamed Novarna, Jul 2026 | |
| Lupin | Mandideep, India | Generics |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| , | ||
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| AndroBioSys | , | Presumed gone |
| Chiromics | , | Website now a penny stock shill |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Ipca Laboratories | Mumbai, India | APIs |
| LabConnect | Johnson City, TN | Lab Services |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Vyant Bio | , | Liquidated, Nov 2023 |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| , | part of ElevateBio; fka LifeEDIT | |
| , | War company as of Aug 2026; Merged into purpose-created public shell Jul 2019 | |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| , | Website down Dec 2025 - Feb 2026 | |
| , | Website down Jan 2026 - May 2026 | |
|
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| , | Website down Oct 2025 - Dec 2025 | |
| Vivifi Life Sciences | Bangalore, India | Generics |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Vericel | Ann Arbor, MI | Cellular Products |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| DNAe | London, UK | Next-gen Sequencing |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
|
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| , | Shut down Jan 2026 | |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| Modular Medical | San Diego, CA | Insulin Pump |
| BioChain | Newark, CA | Sample Preparation |
| SL Pharma Labs | , | Website gone May 2018 |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| RSSL | Wokingham, UK | Analytical Services |
| Medtronic | Minneapolis, MN | Medical Devices |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Caidya | Raleigh, NC | Clinical Research Organization |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| , | Acquired by Sensei Biotherapeutics, Feb 2026, took name Jun 2026 | |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Sharp | Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Instapath | Houston , TX | Automated Digital Pathology |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| Amplyus | , | Renamed miniPCR |
| Santen | Emeryville, CA | Ophthalmics |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Apalexo Biotechnologie | , | No info, probably gone |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Batu Biologics | , | Gone 2019? |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Northway Biotech | Waltham, MA | Contract research |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Action Pharma | , | Abbott acquired product, 2012 |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Rytvel Biotechnology | , | |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| EuBiologics | Seoul, Korea | Vaccines |
| Cellink | Blacksburg, VA | Bioprinting |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| Sytera | , | Merged with Sirion Aug 2006 |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| Kulira Technologies | , | Website Gone Oct 2016 |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| T-Ray Science | , | Renamed Verisante |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| QuantaBio | Beverly, MA | PCR equipment |
| Stryker | Portage, MI | Medical Devices |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| Celsis | , | Now AAIPharma |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| Alcon | Houston, TX | Eye-Care Products |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
|
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Piramal | Aurora, ON | CDMO |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| Gennova Bio | Pune, India | mRNA vaccine |
| Parker BioConsulting | , | Sole employee is a professional board member |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| , | Website down Dec 2025 - Apr 2026 | |
| Accellacare | Rocky Mount, NC | Clinical Research |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| Seer | Redwood City, CA | Early Detection |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Emergo by UL | Austin, TX | Medical device consulting |
| Phenomix | , | Shut Down 2011 |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Adalid Sciences | Prague, Czech Republic | Nanoparticles for Drug Delivery |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
|
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Gilead | Oceanside, CA | Small Molecules |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| PPD | Middleton, WI | Contract R & D, Consulting |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Quiescence Technologies | , | Website Gone |
| , | Acquired by Viatris, Oct 2025 | |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| Baylor Genetics | Houston, TX | Genetic Testing |
| , | Pivoted to AI Jul 2026; SenlangBio is subsidiary that does drug work | |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Epocal | , | Acquired by Alere, Feb 2013 |
|
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| , | Website gone Jan 2026 - Jul 2026; fka Sun BioPharma | |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Zetra Biologicals | , | Gone |
| Peplin | , | Acquired by Leo Pharma 2009 |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Scynexis | Jersey City, NJ | Small Molecules |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Celunol | , | Merged with Diversa to become Verenium |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| LyoTechnica | , | Gone |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| , | Sold off assets Jun 2026; Filed bankruptcy, Mar 2026 | |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| , | Website down Jul 2025 - Dec 2025 | |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| Traferox Technologies | Mississauga, ON | Organ Preservation |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| Qualiber | , | Presumed inactive, website gone |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| Boston Scientific | St. Paul, MN | Medical Devices |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
|
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
|
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| , | Website down Mar 2026 - Aug 2026 | |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| Gilead | Foster City, CA | Small Molecules |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Virtici | Seattle, WA | Product / Company Incubator |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| CureGene | Shanghai, China | |
| , | Website down Aug 2026; LI gone Jul 2026 | |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Tangent Medical Systems | , | Closed |
| Apotech Consulting | London, UK | Life Science Consulting |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| Lipid Genomics | , | Seems unserious |
| APSciences | , | Website gone Aug 2022 |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| Fairway Medical Technologies | , | Website gone |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| Prokarium | London, UK | Oral Vaccines |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| MicroCam | , | Shut down 2015? |
| Intellimedix | , | Company founder/employee all moved on |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Cytiva | Amersham, UK | Medical Devices |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| XellSmart | Suzhou, China | Cell Therapy |
| CytoLogix | , | Gone, Sep 2012 |
| Xyntek | , | Segment of non-life science business |
| Mabimmune | , | Merged with Neurimmune |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| , | Closed June 2024 | |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| MedTrials | Dallas, TX | Clinical Trial Management |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| TAI Diagnostics | , | Gone |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| , | Website down May 2025 - Oct 2025 | |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| Chrysalis | Burlington, MA | GMP Space |
| Genecare | , | Gone |
| , | Gone before Dec 2025 | |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Originus | , | Gone |
| Nanosonics | Sydney, Australia | Ultrasound |
| Merck KGaA | Singapore, Singapore | |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| , | Acquired by Bora Pharmaceuticals, Oct 2024 | |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Cellanome | Foster City, CA | Multiomics Platform |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| SERB Pharmaceuticals | Ceredigion, UK | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| Admescope | Oulu, Finland | ADME-tox services |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| , | Filings late Jul 2022 - Jun 2026 | |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Affigen | , | Liquidating Fall 2019 |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
|
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Hologic | Beijing, China | Diagnostic, Imaging |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| Veracyte | Austin, TX | Cytology Diagnostics |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| GSL Biotech | , | Acquired by Dotmatics |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| , | Acquired by Xoma, Nov 2025 | |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| , | Website down Nov 2025 - Feb 2026 | |
| BrainCells | , | Website gone Feb 2014 |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| OcuDyne | , | AMD Medical Device |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| MiNK Therapeutics | New York, NY | Cell Therapy, CAR-T |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| , | Acquired by ETAP Group, Oct 2023 | |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| , | Acquired by Eli Lilly, Jun 2026, up to $300M | |
| Prana Therapies | , | |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Apoptos | , | Acquired by Receptos |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| Regenicin | , | Residential address, three employees, no money |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| YishengBio | , | Now YS Biopharma |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Valsphere | , | Website gone Nov 2019 |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| , | ||
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| , | ||
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
|
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| Orchestra BioMed | New Hope, PA | Medical devices |
| HackScience | , | Renamed Cytera, Nov 2018 |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Vasade Biosciences | , | Gone |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Inverness Medical | , | Renamed Alere 2011 |
| NB Therapeutics | , | Gone |
| Metis Laboratories | , | |
| Tribiosys | , | Appears defunct, likely late 2007 |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| Macleods Pharmaceuticals | Daman, India | Generics |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| AxoGlia Therapeutics | , | Ran out of money |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| Getinge | La Ciotat, France | Medical Technology |
| , | Renamed Septal Solutions, Jul 2026 | |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| Proxygen | Vienna, Austria | Cancer Therapies |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Bionode | , | Shut down Mar 2024 |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| tiakis Biotech | Kiel, Germany | Biologics |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| Aptyx | Tempe, AZ | Device CDMO |
| ISM Therapeutics | , | Website Gone, no response from employees |
| Chromtech | Apple Valley, MN | Chromatography Products |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| Mitos Pharmaceuticals | , | Website Gone |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| SERB Pharmaceuticals | Cambridge, MA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| CohBar | , | Shut down, late 2023 |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| Xention | , | All programs halted or disposed of by 2016 |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
|
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| , | Website down May 2025 - Dec 2025 | |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Mediatech | , | Now Cellgro |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Siga | New York, NY | Small Molecules |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Curl Bio | , | Shut down Feb 2020 |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| Avrin | Liverpool, UK | Clinical Research |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
|
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| TCXpress | , | Renamed BlueSphere Bio |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| seqWell | Beverly, MA | Sequencing Service |
| Slainte Bioceuticals | , | Gone |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Agilent | Longmont, CO | High-Throughput Screening Equipment, Imaging instruments |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| Xenova | , | Acquired by Celtic Pharma |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| OD-OS | Irvine, CA | Retinal Laser |
| BiOptix | , | Sold for cryptocurrency ticker use |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Interferon Source | , | Bought by PBL Assay Science |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| SHY Therapeutics | Valhalla, NY | ATP/GTPase Modulating Small Molecules |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| Ceribell | Sunnyvale, CA | Fast EEG |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Pangaea Pharmaceuticals | , | Became Zycos |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Alms Therapeutics | , | Gone Jul 2022 |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| NeurAxon | , | No updates since 2008 |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Acucela | , | folded into Kubota Vision |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| , | Website down Jul 2025 - Mar 2026 | |
| Diploid Genomics | San Diego, CA | Diploid genome sequencing for AI Diagnostics |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Xenomics | , | Now TrovaGene |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| , | Shut down Dec 2025 | |
| , | Product sold to Biodexa, Nov 2023 | |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Intellikine | , | Bought by Millennium 2011 |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| Norac Pharma | Azusa, CA | API Manufacturing |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Indago | , | Renamed Lazurite |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Medtronic | North Haven, CT | Medical Devices |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| Five Star Products | , | Liquidated |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| Mandrake Bio | Bengaluru, India | AI-native protein design and gene editing infrastructure |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
|
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BGI | Hong Kong, China | Genetic Testing |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Cougar Biotechnology | , | Bought by J&J |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Transdermal Technologies | , | Website Gone |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Nuvik Therapeutics | , | No website, very little info |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| G1 Therapeutics | , | |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| NKT Therapeutics | , | Shut down May 2021 |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| Surepharm | , | Liquidating, Apr 2025 |
| Actium Biosystems | , | Gone 2013 |
| Studylog | South SF, CA | Animal Study Workflow Software |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| Arginox Pharmaceuticals | , | Apparently Gone |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| , | Assets acquired by Alexion, Feb 2011 | |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| Tal Medical | , | Gone |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| AllerMAbs | , | Website gone Oct 2022 |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Ribopro | Oss, Netherlands | mRNA Services |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
|
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Vernacare | Chorley, UK | Surgical Devices |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Menarini | Dresden, Germany | Small Molecules |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| Senseonics | Germantown, MD | Medical Devices |
| PeriGen | Cary, NC | Perinatal Devices |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
|
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| AngioChem | , | All employees gone, no info, presumed gone |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| Metris Therapeutics | , | Presumed Gone |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Grunenthal | Origgio, Italy | Small molecules |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| NormOxys | , | Gone |
| Pharmexon | Prague, Czech Republic | Consulting |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Rheos Medicines | , | Shut down Dec 2022 |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| , | Owner gone, filings late Nov 2023 - Aug 2026 | |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| , | Website down Sep 2025 - Feb 2026 | |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| , | Renamed Cytonome, Jul 2003 | |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| Wacker | Halle, Germany | Biologics CDMO |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| , | Website down May 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Biophytis | Paris, France | Therapies for aging diseases |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Sea Medical Systems | , | Gone |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| , | Renamed Kapadi, Nov 2025 | |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| , | Renamed Carvolix, Feb 2026 | |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| , | Acquired by Edwards, Oct 2024 | |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
|
Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| QuatRx | , | Acquired by Shionogi, 2017 |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| BioAro | Calgary, AB | LIMS, Omics software |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Lusochimica | , | Owned by Menarini |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| Peritia | Morrisville, NC | Consulting |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Relevant Bio | , | Shut Down Oct 2023 |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| , | Exosomes for neurodegenerative | |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Boragen | , | Renamed Reactive Biosciences |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| MyOme | Palo Alto, CA | Genomic Analysis |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| Transave | , | Merged with Insmed Dec 2010 |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Pivotal BioSciences | , | Shut down late 2018 |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| SOLADIS | , | Acquired by Efor, 2021 |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Stago | Gennevilliers, France | Diagnostics |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| , | Acquired by Hologic, Aug 2019, $85M - 46% ownership as of Aug 2019 | |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| Genomics | Oxford, UK | Human Genetics Platform |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Corin | Cirencester , UK | Orthopedics |
|
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Epigenos Biosciences | , | |
| Dopl Technologies | Seattle, WA | Imaging |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Qardio | Covina, CA | Portable Heart Monitors |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| , | Renamed Peritia, Jan 2026 | |
| , | Website down Jan 2026 - Mar 2026 | |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Kiecana Clinical Research | , | Now KCR |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
|
Verona, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Fujifilm Biotechnologies | Hillerød, Denmark | Biologics Development & Manufacturing |
| R2M Pharma | South SF, CA | Drug Development Services |
| Devsynthesis | Austin, TX | Chemistry CRO |
| Regis Chromatography | Morton Grove, IL | Synthesis & Separations |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Verana Health | San Francisco, CA | Clinical Database |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| Bakhu Pharma | , | Bankrupt, location sold |
| Quantificare | Maringa, Brazil | Medical Imaging |
| Allsino | Hangzhou, China | APIs, Excipients |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| CanCure | , | No news 2017 - 2024 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| ImmunArray | , | Shut Down, 2021 |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| Lupin | Coral Springs, FL | Generics |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| Arna Pharma | Sydney, Australia | Generics |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Verenium | , | Bought by BASF, Dec 2013 |
| , | Website down Jul 2025 - Dec 2025 | |
| Prominex | San Diego, CA | POC Diagnostics |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| , | Website down Jun 2025 - Dec 2025 | |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| Biotia | Long Island City, NY | AI Genomics |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Stada | Belgrade, Serbia | Generics |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
|
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Sonexa Therapeutics | , | Closed 2013 |
| Oak BioSciences | , | Shut down Nov 2024 |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Target Medicals | , | No news 2016 - Oct 2024 |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| AbbVie | Dublin, Ireland | Medical Devices |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Alumis | South SF, CA | Autoimmune Treatments |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Spirox | , | Bought by Stryker, Jul 2017 |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Eisai | Nutley , NJ | Small Molecules |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| DesignMedix | , | Shut down Aug 2020 |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
|
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| Predictive Therapeutics | , | Renamed NeoTX |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Getinge | Englewood, CO | Medical Technology |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| Synthace | London, UK | Development Software |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| VitalMedix | , | Out of Money 2010 |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| FHC | Bowdoin, ME | Medical Devices |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Gene ID inc | , | Website taken over |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Chiron | , | Bought by Novartis |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Inspirata | North York, ON | Cancer Insights |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| , | Website down, COO gone Oct 2025 | |
| , | Shell used for reverse merger by Serapha Bio, Jun 2026 | |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| EVA Pharma | Giza, Egypt | Branded Generics |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
|
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Sirana Pharma | , | Merged with Apexis Bio |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Virscio | New Haven, CT | Contract Research & Consulting |
| Allotera Therapeutics | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Grunenthal | Quito, Ecuador | Small molecules |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| Denizen Biologics | , | Shut down Mar 2023 |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| NeuralInk | Fremont, CA | Neural Implants |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Celerion | Lincoln, NE | Clinical Research |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| Tico Bio | , | Renamed Inso Biosciences |
| Norgine | Vienna, Austria | Specialty Pharma |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| DSG | Blue Bell, PA | Clinical Trial Software |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Geron | Foster City, CA | Small Molecule |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Qrativ | , | Folded into nFerence |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Allux Medical | , | Shut down, Feb 2009 |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| , | Renamed Envue, Feb 2026 | |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
|
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| , | Website down Jul 2025 - Oct 2025 | |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| tte laboratories | , | Acquired by Transcat |
| UniXell Biotechnology | Shanghai, China | Cell Therapy |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| CoRegen | Houston, TX | Genetically Engineered T Reg Cells |
| , | Pivoted to defense contracting, Jan 2026 | |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| , | Acquired by Inizio, Dec 2025 | |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| , | Website down Sep 2025 - Feb 2026 | |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| , | Acquired by Frontage, Jul 2021 | |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Targovax | , | Renamed Circio, Apr 2023 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| Hubot CDMO | South Bend, IN | Contract Filling |
| Northern Lipids | , | Renamed Transferra |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Percivia | , | Shut Down 2012 |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Atugen | , | Acquired by SR Pharma 2005 |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| , | Website down Jul 2025 - Nov 2025 | |
| VedaLab | Cerisé, France | IVD rapid tests |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Piramal | Grangemouth, UK | CDMO |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Apini Therapeutics | , | |
| , | Renamed LeonaBio, Jan 2026 | |
| Grid Biosciences | New Territories, China | Vaccines |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| Excelya | Boulogne, France | Clinical Research |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| , | No news Sep 2010 - Oct 2025 | |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| Antitope | , | Now part of Abzena |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| , | Website down Jan 2026 - May 2026 | |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| PathAI | Boston, MA | AI Powered Pathology |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| InsightRX | San Francisco, CA | Dosing Model |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Axial Biotech | , | Closed Mar 2013 |
| , | Acquired by BMS, Dec 2025, $1.5B | |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| Cambridge, | Small Molecules for bacterial infections | |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| , | Assets being sold off May 2026 | |
| , | Website taken over Jul 2026 | |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Biowest Therapeutics | , | Website Gone |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| CelerDx | , | Tiny startup that went nowhere |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Tecomet | Santa Ana, CA | Orthopedics CNC Machining |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Sanarus | , | Acquired by Hologic, 2020 |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Acquired by Fujirebio, 2022 | |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Champions Biotechnology | , | Now Champions Oncology |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Clinisys | Tucson, AZ | LIMS Platform |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| BioRelix | , | Restructured. Unknown Status. |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Proteonomix | , | Shell Company |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Ackley Hartnett | Langhorne, PA | Tablet Machines |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| Wetlin Research Associates | , | Centerwatch only |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Delpharm | Reims, France | Contract Manufacturing |
| AxoTect | , | Phantom company |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| Diamante | Verona, Italy | Immunotherapies Manufacured in Plants |
| , | Nothing happening Aug 2026 | |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| BGI | Shenzhen, China | Genetic Testing |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| , | Website down Feb 2026 - Jul 2026 | |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| Delpharm | Evreux, France | Contract Manufacturing |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| Silenseed | , | Renamed Silexion |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| , | Acquired by Principal Technologies, Dec 2024 | |
| Analogic | Canton, MA | Medical Imaging |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| bespark*bio | Vienna, Austria | Consulting |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Bacthera | , | Liquidating, Feb 2025 |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| Agendia | Irvine, CA | Breast Cancer Assay |
| iKaryos Diagnostics | , | Gone |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| Abcellute | , | Dissolved, Sep 2016 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Altasciences | Auxvasse, MO | Contract Research |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Lunit | Seoul, Korea | AI Image Analysis |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| , | Website down Sep 2025 - Feb 2026 | |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Diassess | , | Renamed Lucira Health |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Putney | , | Acquired by Dechra, Mar 2016 |
| , | Shut down Jan 2024 | |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Alan Laboratories | , | Website gone, Jan 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| Plexision | Pittsburgh, PA | Diagnostics |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Genuine Biosystem | Chennai, India | IVD Products |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Sanofi | North York, ON | Biologics, Vaccines |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| , | Website down Aug 2025 - Jan 2026 | |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| OBDURO Biotechnologies | , | never a registered CA business |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Rhaeos | Evanston, IL | Shunt Monitor |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| Roche | Mississauga, ON | Small Molecules |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| EndoInSight | , | Website taken over Sep 2021 |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| DIAsource Diagnostics | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Dalex Biotech | , | Gone |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| Avivo BioOptics | , | Website down Dec 2022 |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| Tensys Medical | , | Website gone Sep 2017 |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| , | Now Nexus Spine | |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| CBH ClinTrials | , | now CenExelCBH |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Novo Nordisk | Bohumil, Czech Republic | Diabetes, obesity, liver disease and other therapeutic areas |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Infectex | , | Website taken over May 2020 |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Delpharm | Orléans, France | Contract Manufacturing |
| Convergen LifeSciences | , | Renamed Genprex |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Intica Biomedical | , | Bankrupt 2014 |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| Alderon Biosciences | , | Presumed gone |
| Cell Targeting Inc | , | Bought by Biotime |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Genencor | , | Bought by DuPont |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Altos Therapeutics | , | Gone Jun 2019 |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| , | Acquired by Canoa, Aug 2019 | |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| VALOS | Genova, Italy | Clinical Statistics |
| Inexia | , | Acquired by Centessa |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Personalis | Fremont, CA | Genome Services |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Semaphore Solutions | Victoria, BC | Lab Software |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| Alchemgen | , | Gone |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Sure Genomics | , | Gone 2014? |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| ViaCord | , | Part of PerkinElmer |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| Ximedica | Providence, RI | Medical Device Services |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| , | ||
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Appili Therapeutics | Halifax, NS | Small molecule |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
|
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| ABS Bio | New Castle, DE | Custom Bioreagents |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| NeuroTherapeutics | , | Gone |
| Vistin Pharma | Oslo, Norway | Generics |
| CP Life Science | , | Split and became Medvacon |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Upstate Biotechnology | , | Closed 2005 |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| , | Website down Jul 2025 - Jan 2026 | |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| , | Website down Jan 2026 - Apr 2026 | |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Drugabilis | Villejust, France | Druggability Services |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| MSN Labs | Hyderabad, India | Generics |
| Organon (2) | Jersey City, NJ | Women's Health |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| Aliri | Loos, France | Contract Mass Spec |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| Warnex | , | Merged into DIAGNOS Inc |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| RetiPharma | , | Dissolved Nov 2019 |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Almirall | Barcelona, Spain | Small Molecules |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| , | ||
| TransCellular Therapeutics | , | Gone 2019 |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| , | Website down Oct 2025 - Feb 2026 | |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| QuantuMDx | Newcastle, UK | Diagnostics |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Allez Health | Carlsbad, CA | Biosensors |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
|
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Renamed PICO BioScience, Jun 2026 | |
| AlloThera | , | Gone, 2018 |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Dexcom | San Diego, CA | Glucose Monitors |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| , | Website down Jul 2025 - Dec 2025 | |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| Plureon | , | Website gone, one employee after 17 years |
| Nanogen | , | Now Epoch Biosciences |
| Monobind | Lake Forest, CA | IVD |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| Biotrin International | , | Renamed Diasorin? |
| GEROPHARM | Moscow , Russia | Large drug maker |
| , | Acquired by Guard Therapeutics, Jun 2026 | |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| AbGenomics | , | Renamed Altrubio |
| FemtoVox | , | |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| CO.DON | Teltow, Germany | Cell Therapies |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| Sancilio | , | Now Micelle BioPharma |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| Pharmaron | Beijing, China | R&D Services |
| Berg Pharma | , | Now just Berg |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Sequel Pharmaceuticals | , | Gone |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Altasciences | Everett, WA | Contract Research |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| Niche Generics | Arlesey, UK | Contract Generics |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Quanta Biosciences | , | Renamed QuantaBio |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| ErVimmune | Lyon, France | Cancer Vaccines |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| EyeCyte | , | Gone 2014 |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| Laureate Pharma | , | Acquired by Gallus |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| CeNeRx | , | Shut Down, 2013 |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| Martek Biosciences | , | Bought by DSM |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Minntech | , | Now Medivators |
| PharmedArtis | , | Gone 2019 |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| HCW Biologics | Miramar, FL | Immunotherapy |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
|
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Novonesis | Bangalore, India | Enzymes |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Natera | San Carlos, CA | Prenatal Testing |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| DiaGenic | , | Switched to energy sector |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Sepracor | , | Now Sunovion |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| Glide Pharma | , | Renamed Glide Technologies |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Vitrology | , | Acquired by SGS, May 2012 |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Parion Sciences | Durham, NC | Mucosal Targets |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
|
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Strides Arcolab | , | Now just Strides |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| , | Website down Feb 2026 - Aug 2026 | |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| OFD Biopharma | Albany, OR | Lyophilization |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| , | Acquired by Lilly, Feb 2026, up to $2.4B; fka Oroboros Bio | |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| , | Renamed Indero | |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| Nvelop Therapeutics | , | |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Neurogene | Houston, TX | Genetic Therapies |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| CoMind | London, UK | Non-invasive brain monitoring system |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| EMS | Hortolândia, Brazil | Small Molecules |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Daktari Diagnostics | , | Gone 2017 |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| Nuevolution | , | Bought by Amgen May 2019 |
| Accellacare | Winston-Salem, NC | Clinical Research |
| Calico | South SF, CA | Aging treatments |
| Getinge | Hechingen, Germany | Medical Technology |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| , | Acquired by Alcon, Sep 2025 | |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| TamuroBio | , | Shut Down Jun 2024 |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| GL Technologies | San Diego, CA | Calibration Services |
| 7TM Pharma | , | Gone |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| , | Website down Aug 2025 - Jan 2026 | |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Ameridose | , | Shut Down 2012 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| , | Bankrupt Jun 2025 | |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Antyra | , | Gone |
| , | Website down Jul 2025 - Jan 2026 | |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| , | One person, possibly moved to AK | |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Dynatherm Medical | , | Shut down 2012 or later |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Rubicon Research | Thane , India | Generics |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
|
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| AtheroGenics | , | Assets Sold Off 2009 |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| Cedilla Therapeutics | , | Shut down May 2023 |
| Compugen | Holon, Israel | Biologics |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| Rubix Device | , | Website gone, Aug 2017 |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Sinusys | , | Shut down 2023 |
| , | Acquired by hVIVO, Dec 2019 | |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| , | Shut down Mar 2026 | |
| Parexel | Harrow, UK | Clinical Research |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| Phlow | Richmond, VA | Small Molecule CDMO |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| , | Website down Apr 2026 - Aug 2026 | |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
|
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Concordia Healthcare | , | Now Concordia International |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| Ergomed | Krakow, Poland | Clinical Research |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
|
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Remo CRO | , | Seems to be rebranded as Supeira |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| MacuClear | , | Website gone Jan 2019 |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| , | Winding down, Dec 2025 | |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| ERBC | Baugy, France | Non clinical CRO |
| CSL Behring | King of Prussia, PA | Biologics |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| Sanovel | Silivri, Turkey | Generics |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
|
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| , | Website down Feb 2026 - Jul 2026; Virtual, US/Hong Kong | |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Apaxis Medical | , | Gone 2019 |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| DecImmune Therapeutics | , | Gone 2017 |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Novotech | Melbourne, Australia | Clinical Research |
| Molsoft | San Diego, CA | Drug Design Software |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| , | Website down Aug 2025 - Jan 2026 | |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| Palleos | Wiesbaden, Germany | Clinical Services and Consulting |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Medivector | , | Gone late 2018 |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| Procognia | , | Website Gone, Layoffs 2014 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| , | Website down Jan 2026 - May 2026 | |
| CovX Research | , | Bought by Pfizer |
| Actera Pharmaceuticals | , | Closed |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| MabPrex | , | Out of business, 2016 |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| Effipharma | , | Marked as closed by Google |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Quartet Medicine | , | Wound down, Nov 2017 |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
|
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Atanse | , | Website gone, May 2018 |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| ARCBio | , | Shut down 2014 |
| Coferon | , | Renamed BlinkBio |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Novita Healthcare | , | Renamed TALi Digital |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
|
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Avexxin | , | Rebranded as Coegin Pharma |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| , | Acquired by Sartorius, Apr 2025 | |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Alper Biotechnology | , | Gone |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Cytovale | South SF, CA | Sepsis Detection |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| Bruker | Billerica, MA | Scientific Instruments |
| , | Website down Dec 2025 - Jun 2026 | |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| ClearView | Newton, MA | Strategic Consulting |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
|
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Avatar Biotechnologies | , | Gone 2010 |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| PreventAGE Health Care | , | fka Journey Biosciences |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| Catylix | , | Shut down Oct 2021 |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| , | LI gone Jul 2026; Website emptied Jul 2026 | |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| LumaBridge | San Antonio, TX | Clinical Research |
| IQVIA | Lenexa, KS | Clinical Research |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| Psomagen | Rockville, MD | Genetic Sequencing |
| Bioxene | , | Website gone, Company Presumed gone |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Lorantis | , | Merged with Celldex 2005 |
| Evinco Therapeutics | , Australia | NK cell-derived extracellular vesicles for Alzheimer's and neuroimmune diseases |
| , | Winding down Jul 2026 | |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
|
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| MSM Protein Technologies | , | Gone Jun 2019 |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Bayer | Mailand , Italy | Small Molecules |
| , | Website taken over Aug 2026; fka Bioheart? | |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| DermBiont | Boston, MA | Topical Bacterial Products |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| BA Sciences | Salem, NH | Analytical Services |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| , | Shut down Mar 2026 | |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Caidya | Shanghai, China | Clinical Research Organization |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| Orexia | , | Acquired by Centessa |
| Chrysalis | Waltham, MA | GMP Space |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| , | Website down Dec 2025 - Jun 2026 | |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Curexsys | , | Dissolving, Jul 2024 |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| SCOLR Pharma | , | Closed Mar 2013 |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Omnitura | , | Website gone Jan 2022 |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| Alte Biosciences | , | Gone, Apr 2016? |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| Foghorn Therapeutics | Watertown, MA | Cancer Drug Discovery, Protein Degradation |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| Epigenetix | , | No annual report filed 2013-2019 |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| NeuroVasx | , | No website May 2019, founded 1997 |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Madera Biosciences | , | Shut down Aug 2020 |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| , | Acquired by Medtronic, Jun 2026, $550M | |
|
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Molsid | Lyon, France | Fluorogenic Probes |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Argonaut Manufacturing Services | Carlsbad, CA | CMO specializing in formulation, filling, finishing and final kitting. |
| Trek Therapeutics | , | Shut down Sep 2019 |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| Lifescience Dynamics | London, UK | Clinical & Commercial Strategy |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| TeutoCell | , | Renamed Xell, 2014 |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Biological Dynamics | , | Shut down Jul 2024 |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| DiAthegen | , | Website Gone Oct 2015 |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| , | Renamed SylamoreBio | |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| Elixir Pharmaceuticals | , | Gone |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| Leucid Bio | London, UK | Cell Therapy |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| , | Renamed TransformaBio, Jul 2026 | |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Roche | Basel, Switzerland | Small Molecules |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| , | Part of Genesis Biotechnology Group | |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
|
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| , | Website down Jan 2026 - May 2026 | |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| , | Acquired by CQ Medical, Oct 2023 | |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| Axxam | Milan, Italy | Drug discovery services |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Sundia | , | Part of BioDuro |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| , | Renamed Valion Bio, Apr 2026 | |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| BiVACOR | Houston, TX | Heart replacement |
| PepLib Biotech | Metuchen, NJ | Peptides |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Pharming Group | Leiden, Netherlands | Biologics |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Parcell Labs | , | Website Gone, Oct 2016 |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Bridge Laboratories | , | Gone 2013 |
| VB Spine | Leesburg, VA | Spinal Implants |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Greppo Technologies | , | Renamed Verix Health |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Macleods Pharmaceuticals | Valsad, India | Generics |
| Dualyx | , | Website down Nov 2024 - May 2025 |
|
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| Ascend Genomics | , | Shut down |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Hygtia Therapeutics | , | |
| Accium BioSciences | , | Shut down Oct 2024 |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| , | ||
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| , | Website down Apr 2026 - Jun 2026 | |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Avax Technologies | , | Gone |
| Oncorus | , | Liquidated, Jun 2023 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Akesobio | Zhongshan, China | Antibody Therapies |
| , | Now PiSA USA | |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| , | Gone Sep 2025 | |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| FusionBio | , | Website down Sep 2025 |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| AndroScience | , | Ancient website, no news 2014-2023 |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Avexa | , | Renamed Novita Healthcare |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Verasonics | Kirkland, WA | Research Ultrasound |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| Concerto HealthAI | , | Renamed ConcertAI |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| BBB Therapeutics | , | Bankrupt 2015 |
|
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| , | Acquired by Novartis, Oct 2025, $1.4B; Merged with Talaris Therapeutics, Oct 2023 | |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Birdotech | Shanghai, China | CDRMO |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Macrocure | , | Merged into Leap Therapeutics |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| , | Acquired by Paradigm Health, Jan 2023 | |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| ObsEva | , | Shut down Feb 2024 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| NIOX | Uppsala, Sweden | Asthma management device |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| EmpathBio | , | |
| Central Pharma | Bedford, UK | Filling, Packaging |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| Lexogen | Vienna, Austria | RNA kits |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Ergomed | London, UK | Clinical Research |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| Palingen | , | Renamed IGM Biosciences |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
|
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| , | Website down Jul 2025 - Dec 2025 | |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Smart Biosciences | , | Renamed sb-Peptide |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
|
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Recodagen | , | Gone Jun 2009 |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| Delpharm | Tours , France | Contract Manufacturing |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
|
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| ExcelseBio | , | Part of IntegrityBio |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Piramal | Lexington, KY | CDMO |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Proteintech | Manchester, UK | Research Antibodies |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| PurMa Biologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Resilience | East Norriton, PA | Biomanufacturing |
| AcroCyte Therapeutics | San Carlos, CA | Scaffold-free 3D Cell Culture |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| AQEMIA | Paris, France | AI Drug Discovery |
| Getinge | Tournefeuille, France | Medical Technology |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Nuventra Pharma Sciences | , | Now Allucent |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Cytokinetics | South SF, CA | Small Molecules |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| , | No news Jun 2021 - Jul 2026 | |
| , | Now Hilo, Jul 2026 | |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Neurologix | , | Bankrupt, Liquidation |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| , | Acquired by Merck, Oct 2025, $10B | |
| Novotech | Hong Kong, China | Clinical Research |
| Acrux | West Melbourne, Australia | Drug Delivery |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Recopharma | , | Seems gone |
| Stago | Asnières sur Seine, France | Diagnostics |
| Pangenetics | , | Bought by Abbott |
| Merix Bioscience | , | Renamed Dendrix |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| Cerba Research | Ghent, Belgium | Lab Testing |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| myoscience | , | Renamed iovera |
| FFE Therapeutics | , | Shut down Dec 2013 |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Parexel | Newton, MA | Clinical Research |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| , | Acquired, Jun 2025 | |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| , | No news 2018 - Jul 2026 | |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| ProPharma Group | London, UK | Consulting |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Protalex | , | Failed 2018, shell |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| Affitech | , | Gone |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| , | No news 2021 - Aug 2026 | |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing, CMO |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Tecomet | Farmington Hills, MI | Bone In-Growth Coating, Bearing Surface Solutions |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| OXON | Madrid, Spain | Real World Evidence |
| TibaRay | Fremont, CA | Upright Proton Therapy |
| Eversana | Chicago, IL | Commercialization Consulting |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| Taxolog | , | Website gone, Nov 2015 |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Humanyx | , | No website, Seems gone |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Catalent | Winchester, KY | Contract Manufacturing |
| Peptimmune | , | Liquidated 2011 |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| ScionxBio | Tel Aviv, Israel | Extended-release RNA |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
|
Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| PregLem | , | Acquired by Richter, Oct 2010 |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Ossis | , | 3D-printed orthopedic implants |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Ablacon | , | Shut down Mar 2024 |
| Grifols | Clayton, NC | Biologics |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| Synaptiq Therapeutics | ZZ, Iceland | |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| InvivoGen | San Diego, CA | Life Science Reagents |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Tisucor | , | Shut down Feb 2020 |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| Oscor | , | Acquired by Integer, Dec 2021 |
| Cellenion | Berlin, Germany | Single Cell Testing |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Genaera | , | Dissolved |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Genuiti Therapeutics | , | |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| , | Renamed Hermes Biosciences | |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| AsymBio | Jinshan, China | Biologics CDMO |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| DC Biosciences | , | Shut down Jul 2023 |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Aureon Biosciences | , | Insolvency Proceedings |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| QInstruments | Jena, Germany | Lab Instruments |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| , | Acquired by Processa Pharmaceuticals, Jul 2026 | |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| ProtAffin | , | Winding Down |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Xylo | Boulder, CO | Psychedelics |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| NovoLipid | , | Website Gone |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| EXO Biologics | Liège, Belgium | Exosomes |
| Kuroki Consulting | , | Shut down 2020 |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
|
Cambridge, UK | Isogenica: VHH antibody discovery CRO. World's largest synthetic libraries, 100+ programmes, clinical candidates, discovery timelines cut in half. |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| OxOnc Development | , | Website gone Apr 2018 |
| Solvay | , | Bought by Abbott 2010 |
| Indena | Milan, Italy | CDMO |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| NS Pharma | Paramus, NJ | Small Molecule |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Genomic Solutions | , | Acquired by Digilab |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| AzurRx | , | Merged into First Wave Bio |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| , | Website down Apr 2026 - Aug 2026 | |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Intercytex | , | Liquidated |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| , | Redirecting to Siemens, Feb 2026 | |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| ImmuNext | , | Website gone Feb 2025 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| FyoniBio | Berlin, Germany | Cell Line development, process development, analytical services |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Evogene | Rehovot, Israel | Computational Biology |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| Apotex | Toronto, ON | Small Molecule Generics |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| Therix Medical | , | Seems gone |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| Northway BiotechPharma | , | Renamed Northway Biotech |
|
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| , | Liquidating Feb 2025 | |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Neurokos | , | Gone. No info |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Pathwork Diagnostics | , | Closed 2013 |
| , | ||
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| CFL Biotech | , | Website gone Jul 2020 |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| ACROBiosystems | Zug, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| Progenika | , | Bought by Grifols |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Taligen Therapeutics | , | Acquired by Alexion |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Tecomet | Warsaw, IN | Finishing, CNC Machining, Additive Manufacturing, Grinding |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| PRA International | , | Now PRA Health Sciences |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Via Pharmaceuticals | , | Shell Company |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Nano Science | , | Acquired by EAG, 2006 |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| ActoBio Therapeutics | , | Brought into Precigen |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Cytheris | , | Out of business 2013 |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Trilations | New York, NY | Strategic Consulting |
| Endogene.bio | Paris, France | Data Platform for Uterine Health |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| Abbott | Mississauga, ON | Diagnostics |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| ClinOne | Needham, MA | Clinical Patient Platform |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| , | Acquired by Merit Medical, Jun 2023 | |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Cygene Labs | , | Gone |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Integer | Chaska, MN | Medical & Surgical Devices |
| NeoCura | Beijing, China | Personalized Vaccines |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Minakem | Dunkerque , France | API Manufacturing |
| Antibiotice | Iasi, Romania | Generics |
| Neural Analytics | , | Renamed NovaSignal |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Angiosonics | , | Shut down 2002 |
| ImmunoBiochem | , | No news 2018 -2023 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| , | Website down Jan 2026 - May 2026 | |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| , | Acquired by StarFish Medical, Nov 2024 | |
| , | Subsumed into Synoptics | |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Flen Pharma | , | Now Flen Health |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| Theragenics | Buford, GA | Medical Devices |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Getinge | Plewiska, Poland | Medical Technology |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| IntelliGenome | Houston, TX | CRISPR Diagnostics |
|
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| BINEX | Chungcheongbukdo, Korea | Biologics CDMO |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| InterX | , | Acquired by NeoTX, May 2022 |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Targanta | , | Bought by The Medicines Company |
| , | Acquired by Sun Pharma, May 2025 | |
| EpitoGenesis | , | Gone 2017 |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Inflammix | , | Renamed AnchorBio Solutions |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Zai Lab | Hong Kong, China | Small Molecules |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| , | Website down Aug 2025 - Jan 2026 | |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| ITR Laboratories | Montréal, QC | Toxicology Services |
|
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| GNA Biosolutions | , | Now part of HP Health |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Metabolex | , | Now CymaBay Therapeutics |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| Nya Cell Therapeutics | , | No info |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| HpVac | , | Renamed Atopia Therapeutics |
| AbRegen | , | Website gone, Mar 2019 |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Cytochroma | , | Acquired by Opko Health |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Sequella | , | Ancient website ©2017, last news 2017 |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Cue Health | , | Shut down May 2024 |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| , | Shut down Dec 2024; aka ADITXT | |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Neose | , | Gone |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Proimmune | Oxford, UK | Immunology research products |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Supratek Pharma | , | Website gone Sep 2017 |
|
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| BINEX | Busan, Korea | Biologics CDMO |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| ChronTech Pharma | , | Became real estate company |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Selventa | , | Closed 2016 |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| , | Website down Nov 2025 - Apr 2026 | |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Elanex Pharmaceuticals | , | Gone |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| Dharma Biomedical | , | Website gone Nov 2022 |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| , | Acquired by Bruker, May 2024, €870M | |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| , | Website down Apr 2026 - Aug 2026; aka Yuansisheng Peptide | |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| Eurand | , | Now Aptalis |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| Exodon | , | Website taken over, Jul 2014 |
| EcoSurg | , | Shut Down May 2017 |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| VentriFlo | Pelham, NH | Blood Pumping System |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Forge Biologics | Grove City, OH | Biologics |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| Itero Biopharmaceuticals | , | Website Gone |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Proteologics | , | Apparently Gone |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| WiseGene | , | Website gone jan 2020 |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| Novahep | , | Website down, Oct-Dec 2017 |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| Sarstedt | Nümbrecht, Germany | Lab products |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Hope Medicine | Pudong, China | Antibody Therapy |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| 2 Bridge | Zoersel, Belgium | Consulting |
| NK CellTech | Shanghai, China | Cell Therapies |
| Isolagen | , | Reorganized as Fibrocell Science |
| Accugent Laboratories | , | Website gone Sep 2017 |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| QSV Biologics | , | Website Gone |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Beta-Pro | , | Now Triangle Research Labs |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Vectura | , | |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| Artera | Los Altos, CA | AI Diagnostics |
| Figure8 Surgical | , | Surrendered business in CA |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Cromos Pharma | Portland, OR | Clinical Research |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| , | Acquired by MannKind, Oct 2025, $296M | |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| MMI Genomics | , | Assets bought by Neogen |
| Mankind Pharma | New Delhi, India | OTC? |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Altus Biologics | , | Vertex Subsidiary |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| , | ||
| Molecular Sensing | , | Business revoked Aug 2019 |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| Pfizer | Puurs, Belgium | Packaging |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Syncro Medical | Langhorne, PA | Software development |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Henderson Morley | , | Bankrupt |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Hikma | London, UK | Medication Delivery |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| , | Website down Sep 2025 - Feb 2026 | |
| Epic Pharma | Laurelton, NY | Generics |
| DDi | Singapore, Singapore | Clinical Software |
| VB Spine | Allendale, NJ | Spinal Implants |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Safecor Medical | , | Shut down Apr 2021 |
| Ergomed | Cologne, Germany | Clinical Research |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| Genova Clinical Research | , | Gone, 2014 |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| bioMerieux | Durham, NC | Diagnostics |
| Stiefel | , | Acquired by GSK |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Revolver Therapeutics | Bath, UK | Transcription Block Survival Screen |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Evoke Medical | , | Renamed DirectSync Surgical |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
|
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Adroit Surgical | , | Defunct |
| Ganymede | Palo Alto, CA | Lab Automation |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| Alnis BioSciences | , | No info |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| Ultragenyx Pharmaceutical | South SF, CA | Small Molecules, Biologics |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| , | Website down Jul 2025 - Jan 2026 | |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| , | Acquired by Ligthouse Lab Services | |
| InVasc Therapeutics | , | Shut down 2012 |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| , | Liquidating, May 2026 | |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Refined Diagnostics | Münster, Germany | Lasers |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
|
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Pharmaron | Ningbo, China | R&D Services |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| Phasiq | , | Website gone Jul 2018 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| , | Shut down Feb 2026 | |
| Stago | Franconville, France | Diagnostics |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| TruGenomix | , | Renamed Polaris Genomics |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| OxStem | , | Shut down 2021; Oxford spinout |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Ergomed | Geneva, Switzerland | Clinical Research |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| Zyagen | San Diego, CA | Life Science Reagents |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| TandemAI | New York, NY | AI to democratize the drug development process |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| SphynKx Therapeutics | , | Gone |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Eccogene | Shanghai, China | Small Molecules |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| , | Selling pipeline, winding down Jul 2025 | |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| PhosPrint | Athens, Greece | Laser Bioprinting |
| Biotechnical Services | , | Shut down Apr 2019 |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Celerion | Montreal, QC | Clinical Research |
| Novotech | Shanghai, China | Clinical Research |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Alt Bioscience | , | Now PDx Biotech |
| , | Website down Feb 2026 - Aug 2026 | |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| Cogenics | , | Now Beckman Coulter Genomics |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| Avema Pharma | , | Bought by PL Developments |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Getinge | Getinge, Sweden | Medical Technology |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| August Bioservices | Nashville, TN | Research & Development Services |
| CEL-SCI | Vienna, VA | Biologics |
| , | Renamed Vaxanix, Jul 2026 | |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| HeartVista | , | Renamed Vista.ai |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| Tecomet | Lille, France | Case Design, CNC Machining, Finishing |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| Cortechs.ai | San Diego, CA | Imaging technology |
|
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| 10BioSystems | , | Website Gone, Apr 2016 |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| GlycoEra | Newton, MA | Custom Glycan Platform |
| Scion Medical Technologies | , | Gone 2016 |
| BioPointe Scientific | , | Subsumed into parent |
| QuantumBio | State College, PA | Protein characterization software |
| Zecui Biotech | , | Cell Therapy |
| Profluent | Emeryville, CA | AI Protein Creation |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| NovoKera | , | Merged into Longevity Biomedical |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| , | Shut down Jul 2014 | |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| Correlogic | , | Assets bought by Vermillion 2011 |
| ModeX Therapeutics | Weston, MA | Biologics |
| NovoMedix | San Diego, CA | Small molecules |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Jenken Biosciences | , | Shut down by 2014 |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| Elona Pharmaceuticals | , | Gone |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| CeQur | Greenville, SC | Insulin pump |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Frenova | Waltham, MA | Renal clinical research |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Inductive Bio | Virtual, US | Compound Optimization |
| Oticon | Somerset, NJ | Hearing Aids |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| , | Website taken over Feb 2026 | |
| Rx3 | , | Now Trius Therapeutics |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| BGI | Copenhagen, Denmark | Diagnostics |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Stada | Bad Vilbel, Germany | Generics |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| , | Pivoted to Crypto, Oct 2025 | |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Intact Genomics | St. Louis, MO | PCR kits |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Orthofix International | Lewisville, TX | Medical Devices |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Anacura | Evergem, Belgium | Analytical |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| Piramal | Morpeth, UK | CDMO |
| , | Shut down Jul 2025 | |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroCyte Therapeutics | New Taipei, Taiwan | Scaffold-free 3D Cell Culture |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bestat Pharmaservices | Taipei, Taiwan | Clinical Consulting |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Handa Pharmaceuticals | Tainan City, Taiwan | Specialty pharmaceutical development - generic and 505(b)(2) |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
|
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
|
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Yung Shin Pharm | Taichung, Taiwan | Small Molecules, Generics |
| Zai Lab | Taipei, Taiwan | Small Molecules |