Taiwan - Biotech Companies - Career Pages
| Ergomed | Madrid, Spain | Clinical Research |
| PTM BioLabs | , | Renamed PTM BIO |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Clinical Scientist Group | , | Website gone, employee gone |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Piramal | Rabale, India | CDMO |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Dundee Cell Products | , | Renamed DC Biosciences |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| Abgenix | , | Bought by Amgen 2006 |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Ossur | Irvine, CA | Orthopedic Devices |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Celest Therapeutics | , | |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Novonesis | Paraná, Brazil | Enzymes |
| Biowest Therapeutics | , | Website Gone |
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Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
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Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Spriaso | , | No news 2019 - May 2025 |
| Biotechnical Services | , | Shut down Apr 2019 |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Eminent Services | Frederick, MD | Drug Services |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| , | Website down Jun 2025 - Dec 2025 | |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Remo CRO | , | Seems to be rebranded as Supeira |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| , | Website down May 2025 - Dec 2025 | |
| Safecor Medical | , | Shut down Apr 2021 |
| Rubix Device | , | Website gone, Aug 2017 |
| Vernacare | Maple, ON | Surgical Devices |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
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Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| AstronauTx | London, UK | Alzheimer's Treatments |
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| ROKIT | Seoul, Korea | Organ Regeneration |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| Proteintech | Rosemont, IL | Research Antibodies |
| Fabric Genomics | Oakland, CA | Computational genomics |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
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Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Meissner | Camarillo, CA | Lab Systems |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| XellSmart | Suzhou, China | Cell Therapy |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| NanoTess | Calgary, AB | Biocatalysts |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Neurologix | , | Bankrupt, Liquidation |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| MSD | Carlow, Ireland | Vaccines |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| Tgen Tech | , | Renamed Annoviant |
| , | Website gone Feb 2026 - Apr 2026 | |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| NextCure | Beltsville, MD | Immune Therapies |
| Cardima | , | Bankrupt Dec 2010 |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| 149 Medical | , | Shut down Dec 2022 |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| COR Clinical Research | , | Shut down after owner passed |
| SEQENS | Pune, India | Analytical method validation, API development |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Coating Place | Verona, WI | Drug Delivery Services |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Waters | Milford, MA | Chromatography & Chemistry |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| APT Therapeutics | , | Shut down Mar 2019 |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| VytronUS | , | Shut down Mar 2020 |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| Pharos iBT | , | aka Pharos iBio |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| CureBiotech | , | Presumed gone |
| Nucleus Network | Herston, Australia | Clinical Research |
| Boston Biokeys | , | Gone June 2017 |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| Avatar Medical | Paris, France | Surgical Visualization |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| Ambu | Ballerup, Denmark | Medical Devices |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Vistin Pharma | Oslo, Norway | Generics |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| NanoVector | , | Gone 2019 |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| Nuvelution Pharma | , | Gone 2020 |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Quartzy | Hayward, CA | Lab Management Software |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| , | Website taken over Feb 2026 | |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| Alvea | , | Shut down Oct 2023 |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| , | No news 2019 - Jan 2026 | |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| Carolus Therapeutics | , | Business revoked in CA |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Infectex | , | Website taken over May 2020 |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
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Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Texcell | Gronau, Germany | Contract Research |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| , | Website down Jun 2025 - Dec 2025 | |
| GEROPHARM | Moscow , Russia | Large drug maker |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Theragenics | Buford, GA | Medical Devices |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| OpenClinica | Needham, MA | Clinical Study Software |
| Almac | Durham, NC | Pharmaceutical Services |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| , | Liquidated 2024 | |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| MedGyn Products | Westmont, IL | OBG Devices |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Corza Medical | Boulder, CO | Surgical Devices |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| BrainXell | Madison, WI | Neuronal Research products & services |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| Kendle | , | Acquired by INC Research 2011 |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Carcinotech | Roslin, UK | 3D printed tumors |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Pangaea Pharmaceuticals | , | Became Zycos |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
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Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| , | Renamed Kapadi, Nov 2025 | |
| Madison Vaccines | , | Website gone Dec 2019 |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| JD Bioscience | Seoul, Korea | Small Molecules |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Seneb Biosciences | , | Gone 2017 |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Omixon | Boston, MA | Next-gen sequencing products |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Orbus Pharma | , | Website Gone |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Ignis Therapeutics | Shanghai, China | |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| Statera Therapeutics | , | Shut down Jan 2022 |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Biovays | , | Website Gone |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| Pharmanovia | London, UK | Acquisition of Drugs |
| , | Website down Nov 2025 - Apr 2026 | |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Website down Nov 2025 - Mar 2026 | |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| MicrofluidX | , | Renamed MFX |
| Centinel Spine | West Chester, PA | Spinal Implants |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
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Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Gilead | Edmonton, AB | Small Molecules |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| , | Acquired by HiRO, Aug 2023 | |
| Scientific Industries | Bohemia, NY | Lab equipment |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| , | Winding down Jan 2026 | |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Solventum | St. Paul, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Derma-Cell Research | , | Website gone Nov 2019 |
| AxioMed | , | President left in 2018, not registered in MA |
| Keenova | Malvern, PA | Small Molecules |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Louisville Bioscience | , | Now LBIdx |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Azad Pharma | Montreal, QC | APIs, generics |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| , | Website down Aug 2025 - Jan 2026 | |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Venclose | , | Acquired by BD, Dec 2021 |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
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Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Getinge | Solna, Sweden | Medical Technology |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Synergen | , | Bought by Amgen 1994 |
| Synaptrix | New York, NY | Brain-Computer Interface |
| , | Website down Sep 2025 - Feb 2026 | |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
 |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Sanofi | North York, ON | Biologics, Vaccines |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Adepthera | , | Shut down 2014 |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Scientia Advisors | , | Website gone Jul 2015 |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| AM2PAT | , | Trouble with contaminated products, gone |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Excalipoint Therapeutics | Shanghai, | |
| Acumed | Hampshire , UK | Medical Implants |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| VB Spine | Leesburg, VA | Spinal Implants |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| AbRegen | , | Website gone, Mar 2019 |
| Stago | Taverny, France | Diagnostics |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| , | Pivoted to defense contracting, Jan 2026 | |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Qynapse | Paris, France | Imaging Analysis |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| Velia Therapeutics | , | Shut down Jan 2025 |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Phenomix | , | Shut Down 2011 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Quellthera | , | Subsumed into Liveleaf |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| NeuroFx | , | Renamed Theratome Bio |
| Talima Therapeutics | , | Closed 2011 |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| SynAm Vaccine | , | Gone 2017 |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Gen Plus | Munich, Germany | Formulation |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Genovis | Cambridge, MA | Nanoparticles |
| Agendia | Irvine, CA | Breast Cancer Assay |
| BojiMed | Guangzhou, China | Clinical Research |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| NB Therapeutics | , | Gone |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Nano Oncology | , | Gone |
| Sierra Neuropharmaceuticals | , | Not active |
| MediWound | Yavne, Israel | Wound & Burn Care |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| Advena | Bromsgrove, UK | Medical Device Regulatory Consulting |
| Pathwork Diagnostics | , | Closed 2013 |
| Nasseo | , | Gone |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Alizyme | , | Bankrupt 2009 |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Lavipharm | Peania Attica, Greece | Small molecules |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| Stealth Therapeutics | , | Gone |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| , | Merged into Meridian Bioscience | |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Gene ID inc | , | Website taken over |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| PnuVax | , | No news 2017 - Aug 2024 |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| O-Ray pharma | , | Inactive Jun 2022 |
| TRIA Bioscience | , | Shut down Aug 2021 |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| Stryker | Portage, MI | Medical Devices |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| 10BioSystems | , | Website Gone, Apr 2016 |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| EQL Pharma | Lund, Sweden | Generics |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| , | Subsumed into Synoptics | |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| , | Website taken over Feb 2026 | |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| Elixir Pharmaceuticals | , | Gone |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| , | Website down Dec 2025 - Apr 2026 | |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| RelonChem | Cheshire, UK | Generics |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Kasocio | , | Liquidated, Dec 2019 |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| , | Shutdown Oct 2025 | |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| , | Website down Aug 2025 - Jan 2026 | |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| Combs Lab | , | Website gone Dec 2016 |
| CyteGen | , | 2015 founded, website never active |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Analiza | Cleveland, OH | Physicochemical Services |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Piramal | Mahad, India | CDMO |
| Nesch, LLC | , | Website gone Oct 2018 |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| , | Renamed PKx Bio, 2026 | |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Apnex Medical | , | Shut down, Aug 2013 |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Librede | , | Acquired by Lygos, Jan 2020 |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| Alcon | Houston, TX | Eye-Care Products |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Tigris Pharmaceuticals | , | Now Kirax |
| Jerini | , | Acquired by Shire, 2008 |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| Cilag | , | Joined J&J 1959 |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| StromaCyte | , | Small time, no info. Defunct |
| , | Website down May 2025 - Dec 2025 | |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Amigenics | , | Gone |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Ottobock | Vienna, Austria | Prosthetics |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Actylis | Port Washington, NY | Raw Materials |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Haupt Pharma | , | Merged with Aenova |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| MiNA Therapeutics | London, UK | Small activating RNA |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| Boragen | , | Renamed Reactive Biosciences |
| Medarex | , | Bought by BMS 2009 |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| ConquerX | , | Dissolved Jun 2021 |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Surgisense | , | Presumed gone |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Antios Therapeutics | , | Shut down Feb 2023 |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| PRACS Institute | , | Bankrupt 2013 |
| Microbia-pe | , | Renamed Microbia |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| Anacura | Evergem, Belgium | Analytical |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| , | Website down Jul 2025 - Mar 2026 | |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Tasso | Seattle, WA | Blood-collection products |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| , | Shut down Apr 2026 | |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Solstice Oncology | , | |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| PharmedArtis | , | Gone 2019 |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| Akesis LLC | , | Bankrupt 2015 |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| , | Shut down Oct 2025 | |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| CO.DON | Teltow, Germany | Cell Therapies |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Fuji Yakuhin | Saitama, Japan | Generics |
| DNA Worldwide | Frome, UK | DNA Testing |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| , | No news Mar 2021 - Jan 2026 | |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| Genmab | Utrecht, Netherlands | Biologics |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| ARTham Therapeutics | , | Shut Down late 2023 |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| Genaera | , | Dissolved |
| Velomedix | , | Shut down 2014 |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| , | Website down Jul 2025 - Dec 2025 | |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| , | Renamed Entirety Biomedical | |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Phytomedics | , | Can't find info on it |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| PhytoMedical | , | Apparently Gone |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| , | Shut down Mar 2026 | |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Therorna | Beijing, China | RNA Therapies |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| GeneFab | Alameda, CA | Gene Therapy Services |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Cdymax | Bangalore, India | APIs |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| Viral Genetics | , | Now VG Life Sciences |
| Pulse Biomedical | , | Distributor |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| Erba MDX | , | Website gone Aug 2019 |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
 |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| YishengBio | , | Now YS Biopharma |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| ExThera Medical | Martinez, CA | Blood filtration |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| Accellacare | Cary, NC | Clinical Research |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| Telephus Medical | , | Now Telephus Biosciences |
| , | Shut down Mar 2026 | |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Neurosave | , | Gone 2018 |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| , | Website down Aug 2025 - Jan 2026 | |
| Nusano | Valencia, CA | Radioisotopes |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| TFS | Lund, Sweden | Clinical Research |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| Karykion | , | Website outdated, doesn't seem serious |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| KXT bio | , | Shut down 2019 |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| Cytiva | Piscataway, NJ | Medical Devices |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Scios | , | Bought by JnJ, Feb 2003 |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Kentucky Bioprocessing | , | Now Kbio |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| Esoterix | , | Bought by LabCorp, May 2005 |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Veracyte | South SF, CA | Cytology Diagnostics |
| , | Liquidating Feb 2025 | |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| BioGaia | Stockholm, Sweden | Probiotics |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| , | Website down Jul 2025 - Jan 2026 | |
| Cytoplex Biosciences | , | Gone |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Grannus Biosciences | , | Gone |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| AMDL | , | Now Radient Pharmaceuticals |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Crown Bioscience | Taicang, China | Drug Development |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| Brighton Biotech | , | Only employee is an accountant |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| bioMerieux | Lombard, IL | Diagnostics |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Rad AI | San Francisco, CA | Radiology Software |
| Luvak Lab | , | Dissolved 2013 |
| Ackley Hartnett | Moorestown, NJ | Tablet Machines |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Celunol | , | Merged with Diversa to become Verenium |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| , | ||
| Kinaxo | , | Bought by Evotec |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Calixar | Lyon, France | Membrane Proteins |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Halo Genomics | , | Bought by Agilent |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| , | Website down Jan 2026 - May 2026 | |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Diassess | , | Renamed Lucira Health |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Innovagen | Lund, Sweden | Custom antibody development |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| Northstar Neuroscience | , | Dissolved |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Mologen | , | Liquidating, May 2020 |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| ArisGen | , | Only employee has four other jobs |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| QL Biopharm | Beijing, China | Biologics |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Cunde Medical | , | mRNA Cell Therapy combo |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Abbott | Longford, Ireland | Diagnostics |
| ActoBio Therapeutics | , | Brought into Precigen |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| , | ||
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| Alimentiv | San Diego, CA | Clinical Services |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| REV Clinical | Bakersfield, CA | Clinical Trials |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Gossamer Bio | San Diego, CA | Small Molecules |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Instil Bio | Dallas, TX | Cell Therapy |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Tico Bio | , | Renamed Inso Biosciences |
| Evoke Medical | , | Renamed DirectSync Surgical |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| Ascelegen | , | Closed |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| ReactDx | Melbourne, FL | Wireless Monitors |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Adroit Surgical | , | Defunct |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Baxter | Alliston, ON | Medication Delivery |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Nocimed | , | Renamed Aclarion |
| HEC | , | Website down Dec 2024 - May 2025 |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
 |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| BBB Therapeutics | , | Bankrupt 2015 |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Recensa Therapeutics | , | Only employee gone 2018 |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| , | Website down Oct 2025 - Feb 2026 | |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| RSSL | Wokingham, UK | Analytical Services |
| Gerinda Therapeutics | , | Gone 2009 |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| , | Website down Sep 2025 - Dec 2025 | |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Berg | , | Acquired, Jan 2023 |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| Atlas Genetics | , | Renamed Binx Health |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| Inventa Biosciences | , | Not Active |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Resprotect | , | No update since 2012 as of 2020 |
| Interdict | San Francisco, CA | Small Molecules |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| Mytos | London, UK | Automated Cell Culture |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
 |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| SWITCH Biotech | , | Gone, 2020 |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Endocare | , | Website down Jan 2021 - May 2021 |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| EVA Pharma | Giza, Egypt | Branded Generics |
| Empatica | Cambridge, MA | Seizure Detection |
| FIT Biotech | , | Bankrupt Feb 2019 |
| Scion Medical Technologies | , | Gone 2016 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| BioMAS | , | Ceased operating, Jul 2016 |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| CelerDx | , | Tiny startup that went nowhere |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| Cambrian Bio | New York, NY | Small Molecules |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| OmniGuide | Billerica, MA | Surgical technology |
| Genecure | , | Shut down Sep 2021 |
| Cell>Point | , | Cant find any confirmation they are active |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| Healionics | Seattle, WA | Biomaterials for devices |
| Hookipa Biotech | , | Now Hookipa Pharma |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Hemay Pharmaceutical | Tianjin, China | |
| , | Renamed BreezeBio, Feb 2026 | |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
 |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| NeuroproteXeon | , | Gone 2021 |
| Autotelic | , | Gone 2022 |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Formurex | Stockton, CA | Contract Research |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Tecomet | Kenosha, WI | Implant Components |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| SolaranRx | , | Website taken over |
| MediLink Therapeutics | Suzhou, China | ADC |
| Laborie | Portsmouth, NH | Medical Devices |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| Memento Medicines | , | |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| Novonesis | North Rocks, Australia | Enzymes |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Altiris Therapeutics | , | Presumed Gone |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Novonesis | Bangalore, India | Enzymes |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Altasciences | Harleysville, PA | Contract Research |
| Formex | , | Merged into BioDuro, Nov 2015 |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Inovio Biomedical | , | Seems gone |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| AQEMIA | Paris, France | AI Drug Discovery |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| PPD | Middleton, WI | Contract R & D, Consulting |
| Securecell | Urdorf, Switzerland | Lab automation |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Opis Research | Desio, Italy | Clinical Research |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Dropshot Therapeutics | , | |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| CrelioHealth | Columbia, MD | LIMS |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| DDi | London, UK | Clinical Software |
| Celtaxsys | , | No longer active, Aug 2020 |
| TriVirix | , | Now Nortech Life Sciences |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
 |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| BioTheryX | San Diego, CA | Small Molecules |
| Altair Therapeutics | , | Shut down Feb 2011 |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| Fortrea | Durham, NC | Clinical Research |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| myoscience | , | Renamed iovera |
| Rosedale Medical | , | Now Intuity Medical |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| GMP-Orphan France | , | Renamed Orphalan |
| Maplehurst Genetics International | , | Website gone |
| BioCrea | , | Website Gone, Feb 2018 |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| , | Renamed Aurevia | |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Neuro Bio | Oxford, UK | T14 Blocker |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Translational Bioscience | , | |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Alkermes | Dublin, Ireland | Small Molecules |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Vie Diagnostics | , | Renamed Phoresa |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| Upstate Biotechnology | , | Closed 2005 |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| ImmuneMed | , | Shut Down |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| Metis Laboratories | , | |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| , | Gone Sep 2025 | |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| ObsEva | , | Shut down Feb 2024 |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Alderon Biosciences | , | Presumed gone |
| Vrata Therapeutics | Cambridge, | |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Salvat | Barcelona, Spain | Small Molecules |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| , | Website down Jul 2025 - Dec 2025 | |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Axial Biotech | , | Closed Mar 2013 |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| Martek Biosciences | , | Bought by DSM |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Heraeus Medical | Dorado, PR | Medical Devices |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| Riverain Technologies | Miamisburg, OH | Imaging |
| Salgomed | , | Shut down Apr 2022 |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Protein Metrics | Boston, MA | Protein characterization software |
| AlcaSynn | , | Renamed ChironWells |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Apicore | Gujarat, India | API Development & Manufacturing |
| Action Pharma | , | Abbott acquired product, 2012 |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Piramal | Aurora, ON | CDMO |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Plexanome | , | Gone 2018 |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| TamRx | , | Website taken over Aug 2020 |
| Ergomed | Surrey, UK | Clinical Research |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| Navinta | Ewing, NJ | Generics |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Erbe | Tübingen , Germany | Surgical Systems |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| LakeShore Biopharma | Beijing, China | Vaccines |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| British Biotech | , | Merged into Vernalis 2003 |
| Symansis | Timaru, New Zealand | Reagents |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Empatica | Milan, Italy | Seizure Detection |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| Ergomed | Zagreb, Croatia | Clinical Research |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Medicomp | , | Renamed ReactDx |
| GenturaDx | , | Bought by Luminex 2012 |
| , | Website down Dec 2025 - Apr 2026 | |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| OraSure | Bethlehem, PA | Diagnostics |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Vitrology | , | Acquired by SGS, May 2012 |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| AGILeBiotics | , | Shut down 2024? |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| A2IDEA | , | Only employee left Jan 2024 |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| TME Pharma | Berlin, Germany | L-aptamers |
| Dharma Biomedical | , | Website gone Nov 2022 |
| EmpathBio | , | |
| Califia Bio | , | Shut down May 2020 |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| Inexia | , | Acquired by Centessa |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Texcell | Evry, France | Contract Research |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| , | Website down Jan 2026 - Apr 2026 | |
| Cellevolve Bio | , | Shut down Aug 2023 |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Quantificare | Maringa, Brazil | Medical Imaging |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| NewVac | , | |
| Serica Technologies | , | Bought by Allergan |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| EPD Biotherapeutics | , | |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| Axcend | Lehi, UT | Chromatography Services |
| , | Website taken over May 2026 | |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| 76Bio | , | Shut down Jan 2025 |
| Medicure | Winnipeg, MB | Small Molecule |
| REPROMEDIX | , | Gone 2012 |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Nexus Spine | Draper, UT | Spinal Implants |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Proteins and Peptide Management | , | Now Adocia |
| Aimmune Therapeutics | , | |
| , | Website down Sep 2025 - Feb 2026 | |
| Avecia | , | Bought by Nitto Denko |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| DecImmune Therapeutics | , | Gone 2017 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| TranS1 | , | Renamed Baxano Surgical |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Animas | , | Shut down, Oct 2017 |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Quantificare | Suwanee, GA | Medical Imaging |
| NIOX | Uppsala, Sweden | Asthma management device |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Revotek | , | Website down May 2023 - Sep 2023 |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Altasciences | Scott Township, PA | Contract Research |
| Taxolog | , | Website gone, Nov 2015 |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Optimata | , | Shut down May 2019 |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Accellacare | Downers Grove, IL | Clinical Research |
| Virco | , | Bought by J&J |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| GeneAssess | , | Gone |
| Niche Generics | Arlesey, UK | Contract Generics |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| Five Star Products | , | Liquidated |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| Crown Bioscience | Beijing, China | Drug Development |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Conkwest | , | Website gone Dec 2015 |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| South Coast Clinical Trials | , | |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Baxter | Jayuya, PR | Medication Delivery |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Lupin | Somerset, NJ | Generics |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Boston Scientific | Galway, Ireland | Medical Devices |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| , | Website taken over Mar 2026 - Apr 2026 | |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Restek | Bellefonte, PA | LCGC Equipment |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Envisagenics | New York, NY | Software-based drug discovery |
| GeneoDx | , | Website gone Oct 2019 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| EMKinetics | , | Seems inactive Feb 2021 |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| VedaLab | Cerisé, France | IVD rapid tests |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| MyOme | Palo Alto, CA | Genomic Analysis |
| , | No news Sep 2010 - Oct 2025 | |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| Strike Bio | , | Assets auction, Aug 2017 |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| DC Biosciences | , | Shut down Jul 2023 |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| ApcinteX | , | Centessa Company |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| OD-OS | Irvine, CA | Retinal Laser |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| MGI Tech | Shenzhen, China | Sequencing |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| MediciNova | La Jolla, CA | Small Molecules |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Pathway Genomics | , | Renamed OmeCare |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| RheoSense | San Ramon, CA | Viscometers |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| , | Renamed Envue, Feb 2026 | |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Elegen | San Carlos, CA | DNA writing |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| Gennova Bio | Pune, India | mRNA vaccine |
| , | Website down Sep 2025 - Dec 2025 | |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| Pharmaron | Cardiff, UK | R&D Services |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| SuperX | , | Gone |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Alfacell | , | Now Tamir Biotechnology |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Piramal | Ahmedabad, India | CDMO |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Pharmaron | Hertfordshire , UK | R&D Services |
| Dirui Industrial | Changchun, China | Automated Assays |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Vega Therapeutics | , | Being acquired by Incyte, Jun 2026, $1.25B; Part of Star Therapeutics |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| , | Website taken over, Nov 2025 | |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| Hologic | Beijing, China | Diagnostic, Imaging |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| , | Website taken over Feb 2026 | |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Axbio | Santa Clara, CA | Biochips |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| ProPharma Group | Westlake, OH | Consulting |
| Admescope | Oulu, Finland | ADME-tox services |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| Cell Matrix | , | Acquired by Cancervax |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| BioArra | , | Bought by VWR Nov 2016 |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| Novotech | Bangalore, India | Clinical Research |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| Elm Tree Medical | , | Shut down Nov 2020 |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| , | Website down Oct 2025 - Feb 2026 | |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| Narus Development Solutions | , | Gone |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Synergistix | Sunrise, FL | CRM software |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Sysmex | Tokyo, Japan | Diagnostics |
| XellSmart | Shanghai, China | Cell Therapy |
| CatSci | Cardiff, UK | Contract Research |
| Slainte Bioceuticals | , | Gone |
| Nuredis | , | Shut Down Apr 2021 |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| Assurance Scientific Laboratories | Austin, TX | Molecular Technologies |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| Tequesta BioScience | , | Defunct |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| Veeva Systems | Dublin, OH | Life Science Software |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Cell Targeting Inc | , | Bought by Biotime |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Via Pharmaceuticals | , | Shell Company |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Znomics | , | Bankrupt, Shell Company Now |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Minntech | , | Now Medivators |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| NEC Oncoimmunity | , | Renamed NEC |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| alphaSyx Therapeutics | , | Gone |
| , | Website down Aug 2025 - Jan 2026 | |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Medtronic | Danvers, MA | Medical Devices |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| , | Acquired by QOL Medical, Nov 2025 | |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| Bonenta | , | Website gone |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| , | No website updates since 2013 as of Dec 2025 | |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| LabTwin | , | Merged with Labforward |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| , | Website down Aug 2025 - Jan 2026 | |
| GT Biologics | , | Renamed 4D Pharma Research |
| Zai Lab | Suzhou, China | Small Molecules |
| , | Assets acquired by Alexion, Feb 2011 | |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| iKaryos Diagnostics | , | Gone |
| Apath | , | No website update since 2014, Feb 2023 |
| , | Part of Evogene | |
| Zensun | , | Website gone Jan 2019, Chinese company |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Ufovax | , | Renamed Uvax Bio? |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| Argolight | Pessac, France | Microscopes |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| , | Renamed Cordica Medical, Jan 2026 | |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| Journey Colab | , | Shut down Jan 2025 |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| American Drug Co. | , | Renamed Five Star Products |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| Gene Express Inc | , | bankrupt? |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Sanovel | Silivri, Turkey | Generics |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| OSI Pharmaceuticals | , | Bought by Astellas |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| Medochemie | Limassol, Cyprus | Generics |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| , | Website down Nov 2025 - Apr 2026 | |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| , | Website down Jan 2026 - May 2026 | |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Lacerta Therapeutics | , | Shut down May 2024 |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Axenis | , | Acquired by genOway, Sep 2018 |
| , | Website down Jan 2026 - Mar 2026 | |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Neural Analytics | , | Renamed NovaSignal |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| RJS Biologics | , | Shut down Feb 2019 |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| QSV Biologics | , | Website Gone |
| Convalife Pharmaceuticals | Shanghai, China | Oncology, viruses and aging treatments; bispecific antibodies, small molecules |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| , | Website down Dec 2025 - Jun 2026 | |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| PolyMedix | , | Bankrupt Apr 2013 |
| AIBioTech | , | Assets auction, Aug 2017 |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| , | CEO left 2020, still on website Dec 2025 | |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| , | Renamed SylamoreBio | |
| Advangen | , | Acquired by Cellmid, May 2013 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| , | Shut down May 2026, assets to Innoviva | |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Verana Health | San Francisco, CA | Clinical Database |
| Piramal | Digwal, India | CDMO |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| Profusa | Emeryville, CA | Real-time biosensors |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Genocea Biosciences | , | Winding Down May 2022 |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| AerovectRx | , | No news since 2006, Website gone |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Figure8 Surgical | , | Surrendered business in CA |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Nanoferix | , | Renamed Pendant Biosciences |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Nina Biotherapeutics | , | Gone, after 2015 |
| Gastrotech | , | Now Rose Pharma |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Genetron Health | Beijing, China | Diagnostics |
| Amivas | Waterford, Ireland | Antimalarial |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| EpicGenetics | , | Seems gone Jan 2024 |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| Avrin | Liverpool, UK | Clinical Research |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| HCW Biologics | Miramar, FL | Immunotherapy |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| ChronTech Pharma | , | Became real estate company |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| , | Website down Jan 2026 - May 2026 | |
| AtheroGenics | , | Assets Sold Off 2009 |
| Kerecis | Arlington, VA | Wound Healing |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Pharming Group | Leiden, Netherlands | Biologics |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| Abazyme | , | Dissolved Jun 2017 |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Roche | Buonas, Switzerland | Diagnostics |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| , | Part of ICE Pharma | |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Proimmune | Oxford, UK | Immunology research products |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| CanTx | , | Website gone, Feb 2015 |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| AngioCure | , | Employees all gone, Nov 2017 |
| Genemod | Edmonds, WA | Lab management software |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Bayer | Bergkamen, Germany | Small Molecules |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Novalar | , | Licensing agreement, essentially gone |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Inference | Pune, India | Clinical Trial Services |
| Regulome | , | Gone 2006 |
| ADispell | , | Website gone Apr 2018 |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Allelix | , | Merged with NPS |
| ThauMDx | , | Closed down 2003, out of cash |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| PlaSalus | , | Amateurish looking |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Alvogen | Morristown, NJ | Generics, OTCs |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| Rytvel Biotechnology | , | |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Endotis Pharma | , | Founded in 2003. No info |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Omnitura | , | Website gone Jan 2022 |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| Xylo | Boulder, CO | Psychedelics |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Nizyme | , | Gone Jul 2015 |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| , | Acquired by Frontage, Jul 2021 | |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| Theravance Biopharma | South SF, CA | Small Molecules |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Certego Therapeutics | , | Seems gone May 2023 |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Pharmazz | Greater Noida , India | Small Molecules |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| ResMed | San Diego, CA | Medical Devices |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| , | Acquired by Instem, Jul 2025 | |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Pharmaron | Xi'an, China | R&D Services |
| Eden Biodesign | , | Bought by Watson |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| Opentrons | New York, NY | Lab Automation Robots |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| GlycoSolutions | , | Closed Aug 2015 |
| , | Website down Jan 2026 - May 2026 | |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| Onkor Pharma | , | 10 year old company with no product or website |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Haemonetics | Boston, MA | Blood Management Solutions |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| , | Stopped work Aug 2025, IP company | |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| Orthogonal LLC | Chicago, IL | Medical device software |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| America Stem Cell | , | Changed name to Targazyme |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Refeyn | Oxford , UK | Mass Photometry |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Unigene Laboratories | , | Closed 2013 |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| , | Website down Jul 2025 - Dec 2025 | |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| SK Biotek | , | part of SK pharmteco |
| Eurogentec | Seraing, Belgium | Biologics |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| Kylin Therapeutics | , | Sold |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Intercytex | , | Liquidated |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis la |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Tribiosys | , | Appears defunct, likely late 2007 |
| Abbott | Clonmel, Ireland | Stents |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Vascular Biogenics | , | Now VBL Therapeutics |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| Ionpath | , | Shut down Feb 2025 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| Unilife | , | Bankrupt, Apr 2017 |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| , | Acquired by Xoma, Nov 2025 | |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Endogenx | , | Website Gone Dec 2013 |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| Meissner | Castlebar, Ireland | Lab Systems |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| , | Selling pipeline, winding down Jul 2025 | |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Microislet | , | Bankrupt 2008 |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Octapharma | Lingolsheim, France | Plasma Products |
| AlloCure | , | Website Gone, Jul 2015 |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| Bluestar Genomics | , | Renamed ClearNote Health |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| MSM Protein Technologies | , | Gone Jun 2019 |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| arGEN-X | , | Older name for Argenx |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Medreich | Bengaluru, India | CDMO |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| 3T Biosciences | South SF, CA | TCR Therapies |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| CeNeRx | , | Shut Down, 2013 |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Attralus | Naples, FL | Amyloidosis Treatments |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
 |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| ChunLab | , | Renamed CJ Bioscience |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| Parcell Labs | , | Website Gone, Oct 2016 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| Techne | , | Part of R&D Systems |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| GenQual | , | Inactive, Jun 2017 |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Pristine Bioproduction | , | Not a going concern |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| Tarpon Biosystems | , | Gone by 2017 |
| Ho’ola Therapeutics | , | |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| Steris | Mentor, OH | Contamination Control |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Compugen | San Francisco, CA | Biologics |
| Inflammix | , | Renamed AnchorBio Solutions |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Altan Pharma | , | Acquired by Ethypharm |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| Ganymede | Palo Alto, CA | Lab Automation |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| Convergen | , | |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Relion | , | Shut down 2015? |
| Glide Pharma | , | Renamed Glide Technologies |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Getinge | Tournefeuille, France | Medical Technology |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| InnoCare | Beijing, China | Cancer Treatments |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| RhinoCyte | , | Website moved to a marketing agency domain |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Anfiro | , | Shut down Dec 2019 |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| OncoCell MDx | , | Renamed Immunis.AI |
| Nensius Research | , | Website Gone |
| NextPharma | Limay, France | Contract Research & Development |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| , | Acquired by Waters, 2023 | |
| Bioserv America | , | Shut down Aug 2024 |
| Silenseed | , | Renamed Silexion |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| , | Renamed THX Pharma, Sep 2025 | |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| , | Website down Jan 2026 - May 2026 | |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| , | Acquired by Ligthouse Lab Services | |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| , | Renamed Cyclana Bio | |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| , | Website down Jan 2026 - Mar 2026 | |
| CRI Lifetree | , | Part of PRA Health Sciences |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| Formation Bio | New York, NY | AI Drug Discovery |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| Pfizer | Kalamazoo, MI | Manufacturing |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Medice | Iserlohn, Germany | Small Molecules |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| , | Renamed Stelexis BioSciences | |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| , | Website down Jul 2025 - Jan 2026 | |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Elypta | Solna, Sweden | Liquid Biopsy |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| DMD Therapeutics | , | Gone Nov 2018 |
| Global BioDevelopment | , | Website gone |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| Biomedica | , | Now part of Oxford Biomedica |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| RegeneMed | , | No longer active in CA as of 2014 |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Zelos Therapeutics | , | No site |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| Affivant | , | Part of Roivant |
| MatTek | Ashland, MA | Cell Products, Services |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| Psylo | , | Renamed Xylo, Jan 2025 |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| Angiosyn | , | Acquired by Pfizer 2005 |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| , | Acquired by IQVIA | |
| Angiomics | , | Product being sold by another company |
| , | Renamed Verge Medical, Mar 2025 | |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| Tecomet | Wilmington, MA | Implant Components |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| TcLand Expression | , | Website Gone |
| Scholar Rock | Cambridge, MA | Biologics |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| , | Website down Nov 2025 - Apr 2026 | |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| ArgusEye | Linköping, Sweden | Biosensors |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Baxter | Marion, NC | Medication Delivery |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Amniox Medical | , | Folded into BioTissue |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| BenuBiopharma | , | Shut down Sep 2023 |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| , | Shut down Oct 2023 | |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Bard1 | , | Renamed INOVIQ |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Anvyl | , | Website gone Jan 2021 |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Target Medicals | , | No news 2016 - Oct 2024 |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| BioAMPS | , | Gone |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| , | Website down Oct 2025 - Feb 2026 | |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| Calchan | , | Shut down Dec 2020 |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| CGT Global | Folsom, CA | Tissue Sourcing |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Psomagen | Rockville, MD | Genetic Sequencing |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Axium Pharmaceuticals | , | Dissolved |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| EhmetDx | , | Renamed Ehmet Health |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Antyra | , | Gone |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Eco Quest | , | Now Cynata Therapeutics |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Imcyse | , | Liquidating, Jun 2025 |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| In Veritas Medical Diagnostics | , | Shell company |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Studylog | South SF, CA | Animal Study Workflow Software |
| PharmaDerm | , | Part of Sandoz |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Genstruct | , | Now Selventa |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| QuantumBio | State College, PA | Protein characterization software |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| , | Website down Sep 2025 - Jan 2026 | |
| Ergomed | Frankfurt, Germany | Clinical Research |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| , | No news 2021 - Jan 2026 | |
 |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Amp Orthopedics | , | Shut down, 2012 |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Novometrics | , | Dissolved Dec 2019 |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| , | Website down Jun 2025 - Dec 2025 | |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| Bionovica | , | Website gone Dec 2022 |
| Vali Nanomedical | , | Gone 2016 |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Talis Biomedical | , | |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| XDx | , | Changed name to CareDx |
| Sebia | Lisses, France | Electrophoresis |
| Staburo | Munich, Germany | Clinical Services |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| WideCELLS | , | Shut down Nov 2019 |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| , | Website down Oct 2025 - Feb 2026 | |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| , | Website down Jun 2025 - Dec 2025 | |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Biotheneum | , | Gone |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Enterin | , | Website taken over Feb 2025 |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Berg Pharma | , | Now just Berg |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| Abcam | Cambridge, UK | Antibodies |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| Bioxene | , | Website gone, Company Presumed gone |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Apolife | , | Renamed Biosavita |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| Hemadvance | , | Gone |
| , | Acquired by IQVIA | |
| Piramal | Pithampur, India | CDMO |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| , | Website down Jul 2025 - Dec 2025 | |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| , | Website down May 2025 - Dec 2025 | |
| Tikcro Technologies | , | Liquidating 2021 |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Seeker Biologics | , | Shut down May 2023 |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Accord Healthcare | Ahmedabad , India | Generics |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Z-Factor | , | Centessa Company |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| , | Acquired by hVIVO, Jan 2025 | |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Innexus Biotechnology | , | Gone |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| Howfond | , | Website gone, Jul 2015 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Neurogene | Houston, TX | Genetic Therapies |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Endomag | Cambridge, UK | Biopsy Tracer |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| ImmuNext | , | Website gone Feb 2025 |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Chromocyte | , | |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| Trinity Drug Partners | , | Gone |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| MedCision | , | Assets bought by MedCision, May 2018 |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| CompleGen | , | Shut down Aug 2021 |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| Axcella Health | , | Renamed Axcella Therapeutics |
| Indocruit | , | Gone |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| Olymvax | Chengdu, China | Vaccines |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| Nephrion | , | Closed 2006? |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Nucryst | , | Bought by Smith & Nephew |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| , | Website down Jan 2026 - May 2026 | |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| NKMax America | , | Renamed NKGEN Biotech |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| , | Website down Oct 2025 - Feb 2026 | |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Virapur | , | Acquired by Microbiologics, 2017 |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Inform Genomics | , | Website Gone Nov 2018 |
| Heraeus Medical | Changshu, China | Medical Devices |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| Actium Biosystems | , | Gone 2013 |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
 |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Denk Pharma | Munich, Germany | Generics |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| , | Website down Dec 2025 - Apr 2026 | |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| , | No news 2021 - Apr 2026 | |
| Partek | , | Acquired by Illumina, May 2024 |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| AblaCor | , | Shut down May 2019 |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| Cristers | Suresnes, France | Generics |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Xencor | San Diego, CA | Antibody Discovery |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Cellex | , | Presumed Gone |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Triage Wireless | , | Now named Sotera Wireless |
| Sunol Molecular | , | Assets sold 2005 |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Pharmaron | Tianjin, China | R&D Services |
| Flow Eighteen38 | , | |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| , | Redirecting to Siemens, Feb 2026 | |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| Xencor | Pasadena, CA | Antibody Discovery |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Hutchmed | Hong Kong, China | Oral drugs |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Silence Therapeutics | London, UK | RNAi |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Vyriad | Rochester, MN | Immunovirotherapy |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| NeuClone | Sydney, Australia | Biosimilars |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| Theranos | , | Dissolving, Sep 2018 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| Sojournix | , | Shut down Jun 2021 |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| OptiVia Medical | , | Website looks pretty terrible |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| Vista.ai | Palo Alto, CA | MRI Software |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Parexel | Harrow, UK | Clinical Research |
| Ximedica | Providence, RI | Medical Device Services |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| Prime Biologics | , | Seems gone 2019 |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Algenics | , | Website gone Dec 2015 |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Artimplant | , | Bankrupt, 2013 |
| ABgene | , | Bought by Apogent, Dec 2001 |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Ribonomics | , | Sold to MBL International |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| |
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Movetis | , | Acquired by Shire, Aug 2010 |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Advantagene | , | Renamed Candel Therapeutics |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| VIVUS | Campbell, CA | Small Molecules |
| Apgene Bio | , | Shut down Oct 2020 |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Incyte | Wilmington, DE | Small Molecules |
| Rezolute | Redwood City, CA | Biologics |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Tirupati | New Delhi, India | Generics |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| , | Gone Mar 2024 | |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| , | Shut down Aug 2025 | |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Vedere Bio II | , | Shut down Mar 2023 |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Alaeras | , | Dissolved Jan 2014 |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Lumen Bioscience | Seattle, WA | Biologics |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| NeuMed | , | Website four years since update, no employees on LI |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Originus | , | Gone |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| SeqRight | , | Acquired by GE Apr 2012 |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| Medicure | Princeton, NJ | Small Molecule |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| Ribopro | Oss, Netherlands | mRNA Services |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| CTIBIOTECH | Meyzieu, France | Tissue Sample |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| Accelrys | , | Bought by Dassault, 2014 |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Relevant Bio | , | Shut Down Oct 2023 |
| , | Renamed Cytonome, Jul 2003 | |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| Synosia Therapeutics | , | Acquired by Biotie |
| LC Technologies | , | Renamed EyeGaze |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Syndexa Pharm | , | Closed Jul 2013 |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Eargo | San Jose, CA | Hearing Aids |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| , | Shut down Mar 2026 | |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Asarina Pharma | , | Winding down Jul 2024 |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| , | Acquired by Inizio, Dec 2025 | |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| CombinatoRx | , | Now Zalicus |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Sanofi | Paris, France | Small Molecules |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Panther Orthopedics | , | Shut down Dec 2022 |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| LunaDNA | , | Shutting down Jan 2024 |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| Diversa | , | Merged with Celunol to become Verenium |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| Cogentis Therapeutics | , | No news 2017-2023 |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| G1 Therapeutics | , | |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| PsiThera | Watertown, MA | Oral Small Molecules |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| CMD Medtech | Columbus, OH | Medical Device Development |
| NovaDel Pharma | , | Business dissolved 2014 |
| LifeSensors | , | Website hijacked Feb 2025 |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| South Coast Clinical Trials | , | Website gone |
| , | Acquired by Merit Medical, Jun 2023 | |
| Humacyte | Durham, NC | Bioengineered Vessels |
| , | Renamed Proxoma, Jan 2026 | |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Vyteris | , | Bankrupt 2012 |
| ModeX Therapeutics | Weston, MA | Biologics |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| IntelligentMDx | , | Shut down Feb 2015 |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| GlioCart | , | |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| , | Website down Jun 2025 - Dec 2025 | |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| Spirox | , | Bought by Stryker, Jul 2017 |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| , | Now Nexus Spine | |
| RK Pharma | Pearl River, NJ | Generics |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Indago | , | Renamed Lazurite |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Madera Biosciences | , | Shut down Aug 2020 |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Octane Biotech | Lucknow, India | Generics |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| SE3D | , | Renamed Seed Therapeutics |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| IVAX Corporation | , | Acquired by Teva 2006 |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| SegAna | , | Website down May 2021 - Sep 2021 |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| , | Website down Jan 2026 - May 2026 | |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Helus Pharma | Toronto, ON | Psychedelics |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| , | Renamed Racura Oncology, Dec 2025 | |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Acylin Therapeutics | , | Assets sold 2014 |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| , | Merged with ABX-CRO | |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| , | Acquired by Sartorius, Apr 2025 | |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| Biotia | Brooklyn, NY | AI Genomics |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| , | Became part of Accelerator, Dec 2025 | |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Borean Pharma | , | Gone |
| Pharmaron | Northamptonshire, UK | R&D Services |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Creative Bioinformatics Consultants | , | Gone |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
 |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| SereDigm | , | Gone Nov 2009 |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Ergomed | Kiev, Ukraine | Clinical Research |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| Salus Bioscience | , | Forfeited in CA |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| Profluent | Emeryville, CA | AI Protein Creation |
| Heraeus Medical | Yardley, PA | Medical Devices |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| , | Crypto Pivot, Oct 2025 | |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| Yao Pharma | Chongqing, China | APIs, Generics |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| , | Website down Dec 2025 - Apr 2026 | |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Niowave | Lansing, MI | Radioisotopes |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Apotex | Toronto, ON | Small Molecule Generics |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| CD Genomics | Shirley, NY | Genomics Services |
| Orion Genomics | St. Louis, MO | Biomarkers |
| , | Shut down Jul 2014 | |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| Biotel | , | Acquired by CardioNet, 2010 |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| , | Renamed Singulera, Nov 2025 | |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Lupin | Coral Springs, FL | Generics |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Oncorus | , | Liquidated, Jun 2023 |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| TRPblue | , | Shut down Dec 2023 |
| ChemRegen | , | Seems gone Jan 2022 |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| Advanced Genetic Technologies | , | No info |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| InxMed | Beijing, China | Oncology Treatments |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Seraph Biosciences | Detroit, MI | POC Pathogen Detection |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| Scintillant Bioscience | , | Gone May 2025 |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| BiOM | , | Now BionX Medical |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| Makefield Therapeutics | , | Website Gone |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Sharp | Macungie, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Oncovista | , | Dormant 2016 |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| Apharm | , | Now Biofarma Group |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Aviv Biomedical | , | Shut down 2018 |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| Asuragen | Austin, TX | Diagnostics |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| Spherics | , | Bankrupt |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| AnaBioTec | , | Now Anacura |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| VB Spine | Allendale, NJ | Spinal Implants |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Angioslide | , | Gone, Oct 2009 |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| GeneVivo | , | Unknown Fate |
| , | Website down Oct 2025 - Feb 2026 | |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| XO1 | , | Bought by J&J, Mar 2015 |
| NeurAegis | , | Seems gone, Sep 2022 |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Gangagen | Bangalore , India | Ectolysins |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| Merck KGaA | Singapore, Singapore | Small Molecules, Purification Equipment, etc. |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Fabion Pharmaceuticals | , | Gone 2013? |
| , | Rebranded as VivoSim, Apr 2025 | |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Microsure | Son, Netherlands | Surgical Robots |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| , | Acquired by MannKind, Oct 2025, $296M | |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| Integer | Salem, VA | Medical & Surgical Devices |
| Roche | Pleasanton, CA | Diagnostics |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| EpitoGenesis | , | Gone 2017 |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| AL-S Pharma AG | , | New Dec 2016, no site Aug 2018 |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| IQVIA | Durham, NC | Clinical Research |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| RNA Therapeutics | , | No website Mar 2020 |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| MikrobEX | , | Renamed Rebiotix |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Ximedica | Plymouth, MN | Medical Device Services |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| numares | Houston, TX | Clinical Diagnostics |
| MindWalk | Victoria, BC | Custom Antibodies |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| Saffron Therapeutics | , | Website down Oct 2021 |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| Ativa Medical | , | Renamed Immune IQ? |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Amadix | Valladolid, Spain | Diagnostic development |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| , | ||
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| , | No news 2021 - Jan 2026 | |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Serentrix | , | Seems gone Apr 2022 |
| Rezo Therapeutics | San Francisco, CA | |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| , | Gone before Dec 2025 | |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Byonoy | Hamburg, Germany | Microplate Readers |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| , | Website down Jan 2026 - May 2026 | |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Encorium | , | Bankrupt |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Kate Therapeutics | , | |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Acelyrin | , | Merged into Alumis, May 2025 |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Sitka Biopharma | , | Website gone Jan 2022 |
| Assay Designs | , | Now Enzo Life Sciences |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| UVision 360 | , | Renamed Luminelle |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Compliment Corporation | , | Closed Dec 2011 |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| NormOxys | , | Gone |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Website down Jun 2025 - Dec 2025 | |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Metabasis | , | Bought by Ligand |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| ZyStor | , | Bought by BioMarin, closed |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| DiaVax Biosciences | , | Renamed Helocyte |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| DKP Genomics | , | Dissolved Jul 2025 |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Bioclinica | , | Merged with ERT, 2021 |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Sequella | , | Ancient website ©2017, last news 2017 |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Jaleva Pharmaceuticals | , | Gone |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Website down Jun 2025 - Oct 2025 | |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| EnquBio | San Diego, CA | Contract Research & Services |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| Bracco | Monroe Township, NJ | Imaging |
| superDimension | , | Acquired by Covidien May 2012 |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| , | Became part of Accelerator, Dec 2025 | |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Curry Pharmaceuticals | , | Closed 2008 |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| Activ Surgical | Boston, MA | Surgical Software |
| , | ||
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Curamir Therapeutics | , | Shut down 2020 |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| ProPharma Group | San Diego, CA | Consulting |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Vision Genomics | , | Website Gone, Jul 2016 |
| Orexia | , | Acquired by Centessa |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| SOCIUM | Tokyo, Japan | Contract Research |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| , | being Acquired by Chugai, Oct 2025 | |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Activated Cell Therapy | , | Changed name to Dendreon |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| PepVax | , | Gone 2024 |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| , | Part of Normec | |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Lux Biosciences | , | Gone |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| TransGenRx | , | Bankrupt |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| SGS Quay Pharma | , | |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| , | Acquired by Insphero, Nov 2025 | |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| Eos Biotechnology | , | Gone 2005 |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| CorWave | Clichy, France | Blood Pumps |
| EmpowerPharm | , | Shut down |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| CO.DON | Leipzig, Germany | Cell Therapies |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| E3X Bio | , | Shut Down Mar 2019 |
| PPL Therapeutics | , | Sold in 2003 |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Advansta | San Jose, CA | Protein characterization products |
| Deinove | , | Bankrupt Mar 2023 |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| SelectX | , | Website hacked; No updates since 2011 |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Cytera CellWorks | , | Renamed Mytos |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| Xenomics | , | Now TrovaGene |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Premier Biomedical | , | Pivoted out of life science |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| , | No news 2017 - Apr 2026 | |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| , | Website down Aug 2025 - Dec 2025 | |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Lusochimica | , | Owned by Menarini |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| icometrix | Leuven, Belgium | Imaging AI |
| Cureport | Worcester, MA | Nanomedicines |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| , | Website down Aug 2025 - Jan 2026 | |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Wetlin Research Associates | , | Centerwatch only |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| PepLib Biotech | Metuchen, NJ | Peptides |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Baxter | Deerfield, IL | Medication Delivery |
| Stago | Asnières sur Seine, France | Diagnostics |
| Corin | Cirencester , UK | Orthopedics |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Astrum | Paris, France | Clinical Development CRO |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| Aliquot Solutions | , | Shut down Oct 2024 |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| KVK Tech | Newtown, PA | Generics |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| seqWell | Beverly, MA | Sequencing Service |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| , | Renamed Turing Medical | |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Inventprise | Redmond, WA | Vaccines |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| CardioCreate | , | Shut Down Jun 2020 |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Tripos | , | Bought by Certara |
| PluroGen Therapeutics | , | Gone 2013 |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| QuantaBio | Beverly, MA | PCR equipment |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| SFS | Madrid, Spain | Clinical Research Organization |
| SphynKx Therapeutics | , | Gone |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Vante BioPharm | , | Rebranded at Sebra |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| APCRA | , | Shut down 2020 |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| Genomics | Oxford, UK | Human Genetics Platform |
| AJES Life Sciences | , | Renamed L2P Research |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Centricity Research | Toronto, ON | Clinical Research |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| , | Website down May 2025 - Jan 2026 | |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| DoveTree Medicines | , | |
| Menarini | Florence, Italy | Biologics |
| Sophiris Bio | , | Shut down May 2020 |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| TumorEnd | , | Website gone Feb 2019 |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| bioTHER | , | Gone |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| Etubics | , | Rolled into ImmunityBio |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| , | Acquired by Galecto, Nov 2025 | |
| Alkermes | Waltham, MA | Small Molecules |
| SNBL | , | Acquired by Altasciences |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Anaheim Clinical Trials | , | Now CenExelACT |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| TissUse | Berlin, Germany | Multi Organ chip |
| , | Filings late Jul 2022 - Jun 2026 | |
| NNS Clinical Research | , | Gone |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Ribon Therapeutics | , | Shut down May 2024 |
| Alchemgen | , | Gone |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| , | Website down Dec 2025 - Apr 2026 | |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
 |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| ProPharma Group | Windsor, ON | Consulting |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| Imeka | Sherbrooke, QC | Neuroimaging |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Celerion | Tempe, AZ | Clinical Research |
| VersaPharm | , | |
| Gravidas Diagnostics | , | preeclampsia POC test |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Station X | , | Website Gone Mar 2018 |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| Rafagen | , | Website redirecting to Rophibio |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Monobind | Lake Forest, CA | IVD |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Diality | Irvine, CA | Hemodialysis System |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Cellf BIO | , | Website taken over Jan 2019 |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Advanz Pharma | London, UK | Specialty Generics |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| McGee Pharma | , | Merged with Pharmalex |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Invibio | Cleveleys, UK | Implants |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Curexsys | , | Dissolving, Jul 2024 |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Aethox Therapeutics | London, UK | Inhibitors |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| HebeCell | Natick, MA | Cell Therapies |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| , | Website down Dec 2025 - Jun 2026 | |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Onyvax | , | Assets Apparently Acquired |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| ProtonDx | London, UK | Diagnostics |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| , | Bankrupt, ceased operations Mar 2026 | |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Pathfinder Cell Therapy | , | Gone 2016 |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Anergix | , | Shut down Mar 2009 |
| Hematogenix | Tinley Park, IL | Pharma Services |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Roche | Welwyn, UK | Small Molecules |
| Acucela | , | folded into Kubota Vision |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| EVerZom | Paris, France | Exosome Therapeutics |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| GenomeKey | Bristol, UK | IVD Device |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Tempered Biosciences | , | Absurd website has to be gone |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Soletics | , | Website gone Jun 2021 |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Xcede Technologies | , | Gone Jun 2020 |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Comac Medical | Sofia, Bulgaria | European CRO |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| , | No news 2022 - Mar 2026 | |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| Elektrofi | Boston, MA | Biologics Formulation |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Grifols | Durham, NC | Biologics |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| PegaOne | , | Centessa Company |
| Axplora | Pompey, France | CDMO Services |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Protein Forest | , | Bought by Cell Biosciences |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Octapharma | Vienna, Austria | Plasma Products |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Pharmaron | Beijing, China | R&D Services |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| RSSL | Reading, UK | Analytical Services |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Existence Genetics | , | Bankrupt Dec 2012 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Agile EndoSurgery | , | Gone |
| Novotech | Auckland , New Zealand | Clinical Research |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| BGI | Shenzhen, China | Genetic Testing |
| Anulex Technologies | , | Closed 2014 |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Paige | New York, NY | AI Pathology |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| , | Shut down Jan 2024 | |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Biolab | São Paulo, Brazil | Small Molecules |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| TumorGen | San Diego, CA | Cancer Treatments |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| Facet Biotech | , | Bought by Abbott 2010 |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| TCXpress | , | Renamed BlueSphere Bio |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Ergomed | Geneva, Switzerland | Clinical Research |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| NantCell | , | Renamed ImmunityBio |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| tiakis Biotech | Kiel, Germany | Biologics |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Scion NeuroStim | , | Presumed gone |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| CSL Behring | King of Prussia, PA | Biologics |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Protox Therapeutics | , | Now Sophiris Bio |
| ProPharma Group | Raleigh, NC | Consulting |
| Aureon Biosciences | , | Insolvency Proceedings |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| Concerto HealthAI | , | Renamed ConcertAI |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| MLAB Biosciences | Needham, MA | Biologics |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Genuine Biosystem | Chennai, India | IVD Products |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| , | Acquired by Instem, Jul 2025 | |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| , | Website down Dec 2025 - Apr 2026 | |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Savant HWP | , | Gone 2019 |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Collgard Biopharmaceuticals | , | Gone |
| Novahep | , | Website down, Oct-Dec 2017 |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Arbovax | , | Gone |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Benchling | San Francisco, CA | Biotech Software |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| ICON plc. | Farmingdale, NY | Clinical Research |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| Antabio | Labège, France | Antibacterial drugs |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Purdue Pharma | Stamford, CT | Small Molecules |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Singular Genomics | San Diego, CA | Genomics |
| Proacta | , | Gone 2014 |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| , | Renamed Indero | |
| Nymirum | , | Renamed Base4, Feb 2023 |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| AddBIO | , | Gone Oct 2023 |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| X2 Pharma | , | Website Gone |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Gensia Sicor | , | Renamed Sicor |
| Vernacare | Chorley, UK | Surgical Devices |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| nplex biosciences | , | Renamed Nomic Bio |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Abbott | Princeton, NJ | Diagnostics |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Elixir Medical | Milpitas, CA | Stents |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| Tactic Pharma | , | Website gone, Apr 2018 |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| , | Renamed ExGen Dx, Jul 2025 | |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| Vanguard Therapeutics | , | |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Chiromics | , | Website now a penny stock shill |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Celerion | Vienna, Austria | Clinical Research |
| BIOMODEX | , | Acquired by Mentice |
| Targanta | , | Bought by The Medicines Company |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Cytheris | , | Out of business 2013 |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Nostrum Laboratories | Kansas City, MO | Generics |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| OrphoMed | , | Shut Down 2022 |
| Celsis | , | Now AAIPharma |
| DiagnoSearch | Thane, India | Clinical Research |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| Amakem | , | Website gone Dec 2015 |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| , | Renamed WallabyPhenox | |
| Nycomed | , | Acquired by Takeda 2011 |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
 |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Acrux | West Melbourne, Australia | Drug Delivery |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Carticept Medical | , | Dissolved Feb 2020 |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| CMC Biologics | , | Now part of AGC Biologics |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Appia Bio | , | Shut down Aug 2025 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| Enesi Pharma | , | Renamed aVaxziPen |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| AlphaGenix | , | Gone 2014 |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Meabco | , | |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Diamed | , | Bought by Bio-rad |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Redpoint Bio | , | Inactive |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| Ergomed | Cologne, Germany | Clinical Research |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Gamma Therapeutics | , | Gone |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| , | Shut down Jul 2025 | |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Roche | Mannheim, Germany | Diagnostics |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Sanofi | Reading, UK | Small Molecules |
| Stada | Bad Vilbel, Germany | Generics |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| Quest Clinical Research | , | Now part of eStudysite |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Lorantis | , | Merged with Celldex 2005 |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Ottobock | Duderstadt, Germany | Prosthetics |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| RadioRx | , | Now EpicentRx |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| vTv Therapeutics | High Point, NC | Small molecules |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| , | Seems to be News website, Jan 2026 | |
| Unither Pharmaceuticals | Paris, France | CDMO |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| XStalBio | , | Folded |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Stada | Bad Vilbel, Germany | Generics |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| Ectycell | , | Part of Cellectis |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| LinKinVax | , | Rebranded as EnnoDC |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| Pharos Dx | , | Gone |
| PhoreMost | Cambridge, UK | Biologics |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| CFL Biotech | , | Website gone Jul 2020 |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| Pfizer | Clondalkin, Ireland | Biologics |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Rezolute | Bend, OR | Biologics |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| Anergis | , | Liquidating, Jan 2021 |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Raze Therapeutics | , | Closed due to complicated biology |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| NeuroSearch | , | Wound down 2012 |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| ObvioHealth | New York, NY | Clinical Study Software |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Metronomia | Munich, Germany | Consulting & Data Management |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Omneuron | , | Closed |
| Okairos | , | Acquired by GSK, May 2013 |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| BioParadox | , | Shut down Dec 2017 |
| ProUroCare Medical | , | Gone |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| Alkem Labs | Mumbai, India | Generics |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| Traversa Therapeutics | , | Bankrupt |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Genedata | Basel, Switzerland | Bioinformatics |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Mitokine Bioscience | , | Seems to be a research library now |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| VGX Pharmaceuticals | , | Merged with Inovio |
| Tychan | , | Liquidated early 2022 |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Alliqua | Langhorne, PA | Hydrogels |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| , | Website down Nov 2025 - Apr 2026 | |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| Merix Bioscience | , | Renamed Dendrix |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Lacer | Barcelona, Spain | Small Molecules |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| , | Acquired by BICO, Aug 2021, $15M | |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Stada | Belgrade, Serbia | Generics |
| CellASIC | , | Bought by Millipore, May 2012 |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Stago | Clarkston, GA | Diagnostics |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Hovione | Mumbai, India | Contract Manufacturing |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| , | Website down Sep 2025 - Feb 2026 | |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Affigen | , | Liquidating Fall 2019 |
| DelSite | , | Bankrupt |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Domainex | Essex, UK | Drug Discovery Services |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Proteintech | Wuhan, China | Research Antibodies |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Getinge | Vendôme, France | Medical Technology |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Sopherion | , | Website taken over, Mar 2017 |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| Ikano Therapeutics | , | Gone |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Azano Biotech | , | Now Sandia Biotech |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| IQVIA | San Diego, CA | Clinical Research |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| Zyagen | San Diego, CA | Life Science Reagents |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Streck | La Vista, NE | QC & Diagnostic Products |
| , | No news 2019 - Oct 2025 | |
| , | Website down Jan 2026 - Mar 2026 | |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| Nuevolution | , | Bought by Amgen May 2019 |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Qynapse | Boston, MA | Imaging Analysis |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Rose Research Center | Raleigh, NC | Clinical Research |
| , | Website down Jan 2026 - May 2026 | |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| GenoImmune | , | |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Qool Therapeutics | , | Gone Jan 2021 |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| , | Website down Oct 2025 - Feb 2026 | |
| Akceli | , | Shut down, Sep 2004 |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Enovalife | Paris, France | Biometrics and medical writing services |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Antara Biosciences | , | Bankrupt 2007 |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| Epiomed Therapeutics | , | Gone |
| Nodality | , | Gone |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| OraPharma | , | Owned by Valeant |
| SomaServe | , | Renamed ViaNautis Bio |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Epic Pharma | Laurelton, NY | Generics |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| , | Now PamDx, May 2026 | |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| CYTOO Cell Architects | , | |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| Synfini | Menlo Park, CA | AI Drug Design |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Validant | , | Renamed Eliquent Life Sciences |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| ProteoVec | , | Website gone Jul 2015 |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| GenSensor | Nantes, France | Process Analytical Technology |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| |
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Jetequip | Boucherville, QC | Fluid Handling |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Zambon | Bresso, Italy | Small Molecules |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Stago | Maastricht, Netherlands | Diagnostics |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| US Genomics | , | Now PathoGenetix |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Rhaeos | Evanston, IL | Shunt Monitor |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Vernacare | Bolton, UK | Surgical Devices |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Promaxo | Oakland, CA | Small form MRI |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| SmartCells | , | Bought by Merck Dec 2010 |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| Yposkesi | , | part of SK pharmteco |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| MicroStem | , | Gone Jun 2017 |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| Angex Pharmaceuticals | , | Gone 2018 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Partner Therapeutics | Lexington, MA | Biologics |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Xyntek | , | Segment of non-life science business |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Clinisys | Tucson, AZ | LIMS Platform |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| ImmuneWorks | , | Website gone, Apr 2018 |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| CereSpir | , | No news 2020 - Nov 2024 |
| Cerebroscience | , | One employee, website gone |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| MSN Labs | Hyderabad, India | Generics |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| Gerard Biotech | , | Lab supplies, seems defunct |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Stago | Tianjin, China | Diagnostics |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Genta | , | Liquidation 2012 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| UniXell | Shanghai, China | Cell Therapy |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| PharmaGap | , | Shut down 2013 |
| SiliCycle | Québec, QC | Separation Technologies |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| Chrono Therapeutics | , | Shut Down 2019 |
| , | Renamed Algernon Health, Oct 2025 | |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| PeriCor Therapeutics | , | Website Gone |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| MicroPort | Arlington, TN | Medical Devices |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Morphochem | , | Acquired by Deinove, May 2018 |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Alcon | Mississauga, ON | Eye Care Products |
| MantaBio | Beverly, MA | Real-time PCR System |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Invectys | Paris, France | DNA Vaccine |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| , | Acquired by Healx, Sep 2025 | |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| ReSync Bio | , | Acquired by Benchling 2025 |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| , | Website down Dec 2025 - Apr 2026 | |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Sinusys | , | Shut down 2023 |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Deimos Biosciences | , | |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Teva | Toronto, ON | Small Molecules |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Surepharm | , | Liquidating, Apr 2025 |
| Vadovations | , | No info. 2012 SBIR grant |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| HackScience | , | Renamed Cytera, Nov 2018 |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| Silence Therapeutics | Berlin, Germany | RNAi |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| BioRelix | , | Restructured. Unknown Status. |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| Aplagen | , | No activity since 2008 |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Metrohm | Riverview, FL | Lab Data Management Software |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Seer | Redwood City, CA | Early Detection |
| AlphaMab Oncology | Suzhou, China | Biologics |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Precise Bio | , | Gone 2023 |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| Xeris Biopharma | Chicago, IL | Injectables |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Novelty Nobility | Seongnam, Korea | ADCs |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| , | Renamed Trace Biosciences | |
| , | Website down Jan 2026 - May 2026 | |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Cellink | Blacksburg, VA | Bioprinting |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| Nano Science | , | Acquired by EAG, 2006 |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| Repligen | Waltham, MA | Protein Manufacturing |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| Abbott | Irving, TX | Devices |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| VitamFero | , | Website gone Aug 2018 |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Pfizer | McPherson, KS | Sterile Injectables |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| PKPD International | , | Attack website |
| Verus Pharmaceuticals | , | Dissolved |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| , | Website down Aug 2025 - Jan 2026 | |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| , | Acquired by IQVIA | |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| , | Website down Jul 2025 - Oct 2025 | |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| Roche | Laval, QC | Diagnostics |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Shionogi | Florham Park, NJ | Small Molecules |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| Chaperone Therapeutics | , | Gone 2019 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| , | Website down Nov 2025 - Apr 2026 | |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| ProSci | Poway, CA | Antibodies, etc. |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| Rechon Life Science | , | Ancient website Dec 2020 |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| Getinge | Orléans, France | Medical Technology |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| QuA Vodis | , | Gone |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Urogenix | , | Acquired by Astellas |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| ApoImmune | , | Gone 2014 |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Typharm | Norwich, UK | Generics |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Cogenics | , | Now Beckman Coulter Genomics |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Newgen Biopharma | , | Suspended trading due to scandal |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Pfizer | Ringaskiddy, Ireland | API production |
| Ergomed | Prague, Czech Republic | Clinical Research |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Quratis | Cheongju, Korea | Vaccines |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Coley Pharma | , | Acquired by Pfizer |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| GenoMatix | , | Acquired by Intrexon |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| JAMP Pharma | Boucherville, QC | Generics |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| Neurotronik | , | Most employees moved to InnerPulse |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| Tulyp Medical | , | Pressure-driven perfusion system |
| Medtronic | North Haven, CT | Medical Devices |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Evalve | , | Owned by Abbot Vascular |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Creative Enzymes | Shirley, NY | Enzymes |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Amplyus | , | Renamed miniPCR |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Chiron | , | Bought by Novartis |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| , | Filings late Mar 2025 - Feb 2026 | |
| Genomadix | Kanata, ON | Portable PCR |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| Syneos Health | Morrisville, NC | Clinical Development |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| Genomic Solutions | , | Acquired by Digilab |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Qualicaps | Whitsett, NC | Capsules |
| , | Shut down Nov 2025, Tempus acquired assets | |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Celixir | , | Shell acquired Dec 2023 |
| , | Acquired by Olon, 2024 | |
| Brilliant Research | , | Website gone Dec 2018 |
| Syngene International | Bangalore, India | Contract Research |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| , | Website down Sep 2025 - Dec 2025 | |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| , | Website down Dec 2025 - Apr 2026 | |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Revvity | Boston, MA | Diagnostics, Services |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Lyman Biopharma Consulting | , | Switched to writing |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Balboa Biosciences | , | Gone 2010 |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| LifeMax | , | Part of AmMax |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| TrialStat Solutions | Montreal, QC | eClinical |
| OxStem | , | Shut down 2021; Oxford spinout |
| Novita Healthcare | , | Renamed TALi Digital |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| , | Acquired by Generic Specialties, May 2016 | |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| Mepha | Basel, Switzerland | Generics |
| BioSpherex | , | Renamed Metabiomics |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Pharmexa | , | Merged into Affitech, May 2009 |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| , | Website taken over, Feb 2026 | |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| Abselion | Cambridge, UK | Biologics Quantification |
| NeoTrail Therapeutics | , | |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| InnoVoyce | Boston, MA | ENT Lasers |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| ViroPharma | , | Bought by Shire Jan 2014 |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Baccuico | , | Renamed Bactobio |
| Qualiber | , | Presumed inactive, website gone |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| BostonGene | Waltham, MA | Biomedical Software |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Hikma | London, UK | Medication Delivery |
| Accugent Laboratories | , | Website gone Sep 2017 |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| , | Acquired by IQVIA | |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| IQVIA | Parsippany, NJ | Clinical Research |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| , | No news 2019 - Sep 2025 | |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| TocopheRx | , | Gone before 2019 |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Delpharm | Orléans, France | Contract Manufacturing |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Moleac | Singapore, Singapore | Stroke Products |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Cygene Labs | , | Gone |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| Gameto | New York, NY | Female Fertility Extension |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| C3 Jian | , | Now C3J Therapeutics |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| MediQuest Therapeutics | , | Gone? |
| Medley Genomics | , | Website for sale Feb 2021 |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| , | Renamed Aspen Neuroscience | |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| Insulete | , | Website gone, presumed inactive |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| Olon USA | Concord, OH | Contract Research |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Microbiotix | Worcester, MA | Small Molecules |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Core Prognostex | , | Seems inactive |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| AFID Therapeutics | , | Gone 2012 |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Locanabio | , | Shutting down late 2023 |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Syantra | Calgary, AB | Breast cancer blood test |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| Mesoblast | New York , NY | Regenerative Medicine |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| IBA Analytics | , | Website gone Jul 2015 |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Entropia Biosciences | , | Shut Down June 2019 |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Karius | Redwood City, CA | Diagnostics |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| Solace Pharmaceuticals | , | Out of business 2011 |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Aspira Scientific | , | Gone Nov 2015 |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Norgine | Milan, Italy | Specialty Pharma |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| Horiba Instruments | Irvine, CA | Equipment |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Grunenthal | Aachen, Germany | Small molecules |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Satoris | , | Bought by Rules-Based Medicine |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Kurin | San Diego, CA | Blood Collection Technology |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Tuevol Therapeutics | , | Gone by 2020 |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| AndroBioSys | , | Presumed gone |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Telis Bioscience | , | Renamed Alvea |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| MedinCell | Jacou, France | API Delivery Gel |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Nereus | , | Website Gone late 2013, no info |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| , | Seems gone, Feb 2026 | |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Semaphore Solutions | Victoria, BC | Lab Software |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| Accumed Systems | , | Dated website, cant find any employees |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| Ceronco Biosciences | , | Gone 2015? |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| , | Acquired by Instem, Jul 2025 | |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Medtronic | Warsaw, IN | Medical Devices |
| Medistem | , | Bought by Intrexon Dec 2013 |
| MicroPort | Saluggia, Italy | Medical Devices |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| Sharp | Bethlehem, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Abcam | Waltham, MA | Antibodies |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Chromtech | Apple Valley, MN | Chromatography Products |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Omniseq | , | Acquired by LabCorp, 2021 |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| Calyx Pharma | Mumbai, India | APIs |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| Apotech Consulting | London, UK | Life Science Consulting |
| Novocell | , | Renamed Viacyte |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Camurus | Lund, Sweden | Specialty medicines |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Mitokyne | , | Renamed Mitobridge |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Biotrofix | , | Gone, Dec 2014 |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| Genopis | , | Acquired by Wacker Feb 2021 |
 |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Wepredic | Saint Gregorie, France | Cell Lines |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| Helsinn | Iselin, NJ | Small Molecules |
| DDi | Basel, Switzerland | Clinical Software |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| TandemAI | New York, NY | AI to democratize the drug development process |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Getinge | Wayne, NJ | Medical Technology |
| OvaGene Oncology | , | Gone Feb 2020 |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Steba Biotech | , | Renamed ImPact Biotech |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| Mankind Pharma | New Delhi, India | OTC? |
| Confer Health | , | Shut down 2021 |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| ImmunArray | , | Shut Down, 2021 |
| Gene Techno Science | , | Renamed Kidswell Bio |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| DDi | Princeton, NJ | Clinical Software |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| Hydra Biosciences | , | Website gone Mar 2019 |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| LynxDx | Ann Arbor, MI | Diagnostics |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Torpedo Bio | , | |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| Oligasis | , | Changed named to Kodiak Sciences |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| InterGenetics | , | Assets auctioned |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| Best Vascular Novoste | , | Now Novoste |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Monroe Research | Monroe, NC | Clinical Trials |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Ipsen | Dublin, Ireland | Small Molecules |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Hasten Pharma | Hefei, China | Small Molecules |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Xention | , | All programs halted or disposed of by 2016 |
| AdvaStim | , | Shut down, Dec 2017 |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Neuron23 | South SF, CA | AI-drug discovery |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Proteintech | Manchester, UK | Research Antibodies |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Oscor | , | Acquired by Integer, Dec 2021 |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| EMS | Hortolândia, Brazil | Small Molecules |
| Adheren | , | Gone, 2016 |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Klogene Therapeutics | , | Gone 2019? |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Silere Medical Technology | , | Shut down Dec 2013 |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| , | Website down Jan 2026 - May 2026 | |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Calzada | , | Renamed Polynovo |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| , | Website down, Dec 2025 - Jun 2026 | |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Stellartech Research | Milpitas, CA | Electronic device development |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Henderson Morley | , | Bankrupt |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| Ampac Analytical | , | part of SK pharmteco |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| 3DBiopsy | , | Renamed Triopsy |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| ProPharma Group | Bozeman, MT | Consulting |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| Life Stem Genetics | , | Basically gone |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| , | Acquired by Takara Bio, Jan 2025 | |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Lunit | Seoul, Korea | AI Image Analysis |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| InsightRX | San Francisco, CA | Dosing Model |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| MEDISPECTRA | , | Gone 2002 |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| Getinge | Merrimack, NH | Medical Technology |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Applied NeuroSolutions | , | Gone |
| OP2 Drugs | , | Website gone Jan 2020 |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Lectus Therapeutics | , | Sold off product |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| Amorsus | , | Website Gone 8-30-13 |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Entelos | , | Bankrupt |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| Orochem | Naperville, IL | Reagents, Automation |
| OD-OS | Teltow, Germany | Retinal Laser |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Neurophet | Seoul, Korea | AI-Image Processing |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Stada | Bad Vilbel, Germany | Generics |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Signant Health | Horsham, PA | eClinical Solutions |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Biocoat | Horsham, PA | Medical Device Coatings |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| 7TM Pharma | , | Gone |
| Ergomed | London, UK | Clinical Research |
| Denizen Biologics | , | Shut down Mar 2023 |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Cytecs | Münster, Germany | Cell Analysis |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| , | Website down Jan 2026 - May 2026 | |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| Covalent Bioscience | , | Shut down, 2025? |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| , | ||
| Curis | Lexington, MA | Small Molecules |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Biocode Hycel | , | Website gone |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Genyro | San Francisco, CA | DNA Construction Technology |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Copley Scientific | Nottingham, UK | Test equipment |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Dynacare | , | Bought by LabCorp 2002 |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| QuatRx | , | Acquired by Shionogi, 2017 |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Genova Clinical Research | , | Gone, 2014 |
| Cellanome | Foster City, CA | Multiomics Platform |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| Akero Therapeutics | South SF, CA | NASH therapy |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| LeukoSite | , | Acquired by Millennium 1999 |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| CorTechs Labs | , | Renamed Cortechs.ai |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Aviria Biosciences | , | Disappeared |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| , | Website down Nov 2025 - Apr 2026 | |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| Intelliseq | Kraków, Poland | Genome Informatics |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Biogenes | Berlin, Germany | Antibodies |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| Islet Sciences | , | Gone |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| StemBioSys | San Antonio, TX | Stem Cells |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| On-Q-Ity | , | Closed 2013 |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Cambridge Pharma | , | Rolled into parent, SMC |
| Recida Therapeutics | , | |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Verenium | , | Bought by BASF, Dec 2013 |
| Plaxgen | , | Shut Down 2019 |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
 |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| MantraPharma | Lévis, QC | Generics |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Resilience | Alameda, CA | Biomanufacturing |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Avatar Biotechnologies | , | Gone 2010 |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| NextImmune | , | Renamed NXI Therapeutics |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| Pharmathen | Marousi, Greece | Generics |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| 1859, Inc. | , | Shut down Jul 2023 |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| MolPlex | , | Insolvent, 2016 |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Excelya | Boulogne, France | Clinical Research |
| , | Renamed Hubot, May 2026 | |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Scynexis | Jersey City, NJ | Small Molecules |
| MYcroarray | , | Renamed Arbor Biosciences |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Allometra | , | Gone |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| Neuromatters | , | Shut down Dec 2019 |
| , | Acquired by Medicover, Apr 2026 | |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| Abgent | , | Renamed Abcepta, 2019 |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| Ingenetix | Wien, Austria | PCR Products |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| Avontec | , | Gone |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Global Cell Solutions | , | Gone Apr 2018 |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Avistone | Beijing, China | Precision Oncology |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| RepRegen | , | Gone, 2014 |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Gilead | Foster City, CA | Small Molecules |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| CTG Pharma | , | Gone |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| Alper Biotechnology | , | Gone |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| Emergo by UL | Austin, TX | Medical device consulting |
| Vodori | Chicago, IL | Commercial Content Software |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| , | Acquired by Stryker, Sep 2024 | |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| CATO SMS | , | Renamed Allucent, May 2022 |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Roche | Schlieren, Switzerland | Small Molecules |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| BA Sciences | Salem, NH | Analytical Services |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| BrainCells | , | Website gone Feb 2014 |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Allez Health | Carlsbad, CA | Biosensors |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Endologix | Irvine, CA | Medical Devices |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Nuventra Pharma Sciences | , | Now Allucent |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Keenova | Bridgewater, NJ | Small Molecules |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Cuda Pharmaceuticals | , | Presumed gone |
| BioPointe Scientific | , | Subsumed into parent |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Evvy | New York, NY | At-home vaginal microbiome test |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| , | Website down Jul 2025 - Dec 2025 | |
| SVBio | , | Changed name to Lifecode |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Kuano | Cambridge, UK | AI Drug Discovery |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Valitor | Berkeley, CA | Protein therapeutics |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| Macrogen | , | Renamed Psomagen, 2019 |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| , | Gone Jan 2025 | |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Absynth Biologics | , | Website Gone Jan 2019 |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| , | Website hijacked Oct 2025 | |
| Getinge | Växjö, Sweden | Medical Technology |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Owkin | New York, NY | AI for Medical Research |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Satya | Hyderabad, India | Small Molecule |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| CLCbio | , | Acquired by Qiagen, 2013 |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Photonion | Schwerin, Germany | Analytical Equipment |
| Sopharma | Sofia, Bulgaria | Generics |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Persomics | , | Gone 2019 |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Genfit | Loos, France | Drug Discovery |
| PulmoGeniX | , | No business filings 2016-2020 |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| XW Laboratories | , | Renamed XWPharma |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Digene | , | Merged with Qiagen |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Regenicin | , | Residential address, three employees, no money |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Balance Therapeutics | , | Gone late 2020 |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| AGI Therapeutics | , | Bought by Videra |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| SemBioSys | , | Bankrupt, Jul 2012 |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Large Scale Biology | , | Shut Down |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Libra Clinical Research Associates | , | Gone |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| BGI | Kobe, Japan | Genetic Testing |
| GSL Biotech | , | Acquired by Dotmatics |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| SulfaGENIX | , | Website gone, Jan 2019 |
| InterX | , | Acquired by NeoTX, May 2022 |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Corcym | London, UK | Implants, Instruments |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| Sirius Genomics | , | Gone |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| GliaMed | , | Website copyright 2009, seems defunct |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| Pharmascience | Montréal, QC | Generics |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Elan | , | Bought by Perrigo, Dec 2013 |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| Syncro Medical | Langhorne, PA | Software development |
| NeuralInk | Fremont, CA | Neural Implants |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Lean Biologix | Norfolk, MA | Consulting |
| Genae Associates | , | Acquired by IQVIA |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| EuBiologics | Seoul, Korea | Vaccines |
| , | Website down Jan 2026 - May 2026 | |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| ProPharma Group | Fort Washington, PA | Consulting |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Transdermal Technologies | , | Website Gone |
| Abogen | Suzhou, China | mRNA |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| GT Molecular | Fort Collins, CO | PCR Kits |
| Trimeris | , | Merged with Synageva |
| Apoptos | , | Acquired by Receptos |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| Alms Therapeutics | , | Gone Jul 2022 |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| Sciele Pharma | , | Bought by Shionogi |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| , | Acquired by hVIVO, Dec 2019 | |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| VM Discovery | , | 20 yr old company with no info on website |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| CyBio | , | Merged into Jena, Jul 2014 |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| , | Acquired by Novanta, Jun 2026 | |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| New Brunswick Scientific | , | Merged into Eppendorf |
| Avrygen | , | Website Gone, execs gone |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Gensignia | , | Website Gone, Aug 2017 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| Dalex Biotech | , | Gone |
| Biovail | , | Merged with Valeant |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| icometrix | Boston, MA | Imaging AI |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| CBM Biopharma | , | Shut down Nov 2020 |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Catamaran Bio | , | Winding down Jan 2024 |
| , | Renamed PsiThera, Dec 2025 | |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Regulaxis | , | No news 2020-2024 |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Metrohm | Houston, TX | Lab Data Management Software |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| Sytera | , | Merged with Sirion Aug 2006 |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Integrated Genomics | , | Changed to Igenbio |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| Parexel | Sheffield, UK | Clinical Research |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| InteguRx | , | Website taken over, Dec 2023 |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| Omeros | Seattle, WA | Small Molecules |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| Flux Biosciences | , | Shut down, ~2022 |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| Optovue | , | Renamed Visionix Sep 2021 |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| , | Website taken over Feb 2026 | |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| Mardil Medical | , | Website gone Feb 2021 |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| CombImmune | , | Website Gone Jul 2015 |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Vernacare | Blackwood, UK | Surgical Devices |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Grifols | Clayton, NC | Biologics |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Multerra Bio | , | Bankrupt May 2021 |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Cambria Biosciences | , | Gone Feb 2008 |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| Exodon | , | Website taken over, Jul 2014 |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| MaxThera | , | Shut Down Dec 2011 |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| , | Website down Nov 2025 - Apr 2026 | |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Remedium Bio | Needham, MA | Gene Therapy |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| , | Acquired by Xoma, Sep 2025 | |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Point Biomedical | , | Liquidated Jul 2008 |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| DP Clinical | Rockville, MD | Clinical Research |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Fusion Biopharma | , | Presumed gone |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Molsoft | San Diego, CA | Drug Design Software |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| NanoSort | , | Renamed NanoCellect |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| ions.bio | Planegg, Germany | Biomarkers |
| , | Acquired by Affluent Medical, Feb 2026 | |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| restor3d | Durham, NC | 3D printed implants and devices |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| , | Website down Dec 2025 - Feb 2026 | |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| , | Website 404 Sep 2025 - Apr 2026 | |
| Ataia Medical | , | Website taken over Jan 2024 |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Jina Pharmaceuticals | , | |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Novoresearch | , | Gone 2014 |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Claritas Genomics | , | Closed Jan 2018 |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| BianoGMP | Gera, Germany | Oligonucleotides |
| QuantRx Biomedical | , | Shell company |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| , | Winding down, Dec 2025 | |
| InfraReDx | Bedford , MA | Medical Devices |
| , | Now PiSA USA | |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Prolexys Pharmaceuticals | , | Website Gone |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| Vivex Biologics | Atlanta, GA | Tissues |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Immunogen (1) | , | Renamed ImmunogenX |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| RecomGenex | , | Renamed TargetEx Biosciences |
| , | Renamed Motive Health, Jul 2023 | |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Sygene Technologies | , | Website gone Nov 2018 |
| XtalPi | Shenzhen, China | AI Drug Design |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| GeneSeek | , | Bought by Neogen |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Apollo Scientific | Manchester, UK | Research Products |
| Arraystar | Rockville, MD | Microarrays |
| VentriFlo | Pelham, NH | Blood Pumping System |
| , | Website taken over, Nov 2025 | |
| CorDx | San Diego, CA | Diagnostics |
| IDM Pharma | , | Acquired by Takeda |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| GT Apeiron | Shanghai, China | AI Drug Development |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| Piramal | Ennore, India | CDMO |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Biobase | , | Bought by Qiagen, May 2014 |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| , | Renamed BTgen Bio, May 2026 | |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| , | Website down May 2025 - Dec 2025 | |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Viatris (2) | Hyderabad, India | Small Molecules |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Novacta | , | Website Gone, no info |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| Alera Labs | Durham, NC | Contract Research & Services |
| Parker BioConsulting | , | Sole employee is a professional board member |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Excelsyn | , | Bought by AMRI |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| Athlon Pharma | , | No news since 2006 lawsuit |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Patronus Biotech | Singapore, | |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| Neuro3 Therapeutics | Cambridge, | Small Molecules, siRNA |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| GeneDx | Stamford, CT | Genetic Data |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| , | Acquired by Crypto Group, Jan 2025 | |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| Kar Bioanalytical | , | Seem gone |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Phenomyx | , | Gone Jun 2019 |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Prochon Biotech | , | Acquired by Histogenics |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Parexel | Durham, NC | Clinical Research |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| , | Website down Aug 2025 - Jan 2026 | |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Procept BioRobotics | San Jose, CA | Aquablation |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| OriMAbs | , | Gone post 2022 |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| QC Ware | Paris, France | Molecular Discovery Platform |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Spiden | , | Renamed Liom, Jul 2024 |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Agenix | , | Gone, Website taken over |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| , | Renamed Revr Jan 2026 | |
| Cira Discovery | , | Website copyright 2003 |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Apini Therapeutics | , | |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Galileo Research | , | No news since 2012, presumed gone |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| Transave | , | Merged with Insmed Dec 2010 |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| NeuroVista | , | Website Gone, President has new job |
| , | Reportedly Closed Mar 2026 | |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| NexMed | , | Now Apricus Bio |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Lupin | Mandideep, India | Generics |
| Cyto360 | , | Website gone Aug 2018 |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| , | Website down Jun 2025 - Dec 2025 | |
| GlycoRegImmune | , | Changed name to GRI |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Vista Scientific | , | Shut down Dec 2015 |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| DDL | Irvine, CA | Device Testing |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| Helix | San Mateo , CA | Genetic Testing |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| , | Website down, COO gone Oct 2025 | |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Venta Medical | , | Gone, Apr 2017 |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| VitalMedix | , | Out of Money 2010 |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Enlibrium | , | Gone 2018 |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| GeneTrol | , | Merged with CytoPharm |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| AlloThera | , | Gone, 2018 |
| Evolve BioSystems | , | Renamed Infinant Health |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| SourceMDx | , | Assets Sold |
| Kumuda | , | Website gone Mar 2023 |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| , | Website down Jul 2025 - Oct 2025 | |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Insamo | , | |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Valneva | Livingston, UK | Biologics Manufacturing |
| WiseGene | , | Website gone jan 2020 |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Nesher Technologies | , | Shut down Oct 2017 |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| SynapDx | , | Shut down, Mar 2017 |
| Aspira Labs | , | Renamed Aspira Women's Health |
| MetaMorphix | , | Changed to Scidera Genomics |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Anesiva | , | Bankrupt 2010 |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| , | Renamed Verge Labs, May 2026 | |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Hovione | Macau, China | Contract Manufacturing |
| Medivector | , | Gone late 2018 |
| Cebix | , | Shut down, Feb 2015 |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| Piramal | Morpeth, UK | CDMO |
| GlycoEra | Boston, MA | Custom Glycan Platform |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Kirax | , | Website Gone |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| Bioasis Technologies | , | Closing down Jun 2023 |
| August Bioservices | Nashville, TN | Research & Development Services |
| Roche | Basel, Switzerland | Small Molecules |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| Pentapharm | Basel, Switzerland | APIs |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Blu Biotech | , | Website down May 2023, CEO gone |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| NeuMedics | , | Website taken over by massager sales |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| CRIO | Boston, MA | eClinical Software |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| Artera | Los Altos, CA | AI Diagnostics |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Genfit | Cambridge, MA | Drug Discovery |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Maxwell Biosciences | Austin, TX | Antivirals |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Procos | Cameri, Italy | Contract Manufacturing |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| AB ANALITICA | Padua, Italy | Sequencing products |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| Primera Biosystems | , | Now PrimeraDx |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| , | Acquired by Collate, Aug 2025 | |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| , | Website down Sep 2025 - Dec 2025 | |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Vasade Biosciences | , | Gone |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| BioArctic | Stockholm, Sweden | CNS treatments |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Ipsen | Sumter, SC | Biologics |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Bio-Detail | , | Website gone Feb 2023 |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Cyberval | , | Seems inactive Feb 2024 |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| ApniCure | , | Gone 2017 |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| Biomoles | , | Closed Sep 2017 |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| , | Website down Dec 2025 - Apr 2026 | |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| SuraMedical | , | Most employees left, not registered in MN |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Bio-Processing Alliance | , | Website now for a training company |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Semafore Pharmaceuticals | , | Gone? |
| PredxBio | Pittsburgh, PA | Image Analysis |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Amplified Proteomics | , | Shut down Jan 2006 |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| Endovasc | , | Bankrupt 2008 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Palmaz Scientific | , | Bankrupt, 2016 |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Actera Pharmaceuticals | , | Closed |
| Serotiny | , | Acquired by J&J, 2023 |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Delpharm | Evreux, France | Contract Manufacturing |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Bruker | Billerica, MA | Scientific Instruments |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| , | Website down Oct 2025 - Feb 2026 | |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| Resilience | Hamilton, OH | Biomanufacturing |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| Palingen | , | Renamed IGM Biosciences |
| Eisai | Nutley , NJ | Small Molecules |
| Ally Therapeutics | , | Shut down early 2021 |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| Immutics | , | Renamed TrueBinding |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| RFE Pharma | , | Gone 2019 |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| LinkChem | Shanghai, China | CDMO |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Otsuka | Rockville, MD | Small Molecules |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| United Immunoassay | , | Business revoked Jan 2022 |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Barrier Therapeutics | , | Bought by Stiefel |
| Bayer | Mailand , Italy | Small Molecules |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Spear Bio | Woburn, MA | Immunoassays |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| , | Website down Jan 2026 - May 2026 | |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Nexus Genomics | , | Gone 2001 |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| , | Acquired by Arterex, Jun 2023 | |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| DL Develop | , | Website gone, Dec 2018 |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| OBI Pharma | Taipei, Taiwan | Biologics |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Medion Diagnostics | , | Bought by Grifols? |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| PRI Research | , | Renamed Wake Clinical |
| Cytokinetics | South SF, CA | Small Molecules |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| Synergx | , | Owned by Morphogenesis |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| , | No news 2020 - Dec 2025 | |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Qrativ | , | Folded into nFerence |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Avineuro | , | Website taken over Feb 2024 |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Logan Medical Devices | , | Gone? |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Mitos Pharmaceuticals | , | Website Gone |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| MOgene | St. Louis, MO | Genomic Services |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| Y's Therapeutics | , | Website Gone |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| , | Renamed Edding, Feb 2026 | |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| , | Website down Sep 2025 - Feb 2026 | |
| Acculysis | , | Website gone, sole employee with Agilent now |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| IncellDx | , | Renamed HealthBio AI |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| StemPar Sciences | , | Website disappeared, no news |
| TissueNetix | , | Gone Feb 2018 |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| SironRx | , | Website gone Jul 2015 |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| ChondroGene | , | Now GeneNews |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| Cellipse | , | Website taken over May 2020 |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| , | Acquired by Sebia, Dec 2022 | |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| M2 Medical | , | Now Asante Solutions |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| , | Website down Jul 2025 - Dec 2025 | |
| AB Sciex | , | Renamed Sciex |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| May Health | Paris, France | Ovulation Restoration Therapy |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| Obexia | , | Gone |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| Roxall | , | No news 2019 - May 2025 |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Gran Med | , | Gone |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| , | Website down Nov 2025 - Feb 2026 | |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| Arginox Pharmaceuticals | , | Apparently Gone |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| BalinBac Therapeutics | , | Gone 2018 |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| CORONIS | Athens, Greece | Clinical Studies |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| , | Website down Dec 2025 - Apr 2026 | |
| Apollo Spine | , | Renamed G6 Spine |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| DNAe | London, UK | Next-gen Sequencing |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Core Dynamics | , | Gone |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| GeneCopoeia | Rockville, MD | Lab reagents |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| PowderMed | , | Acquired by Pfizer 2006 |
| Heart Repair Technologies | , | |
| Bioenza | , | Website gone Sep 2017 |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Pfizer | Surrey, UK | Consumer Healthcare |
| , | Acquired by Kite, Aug 2025 | |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| ClinOne | Needham, MA | Clinical Patient Platform |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| SK Biotek | , | part of SK pharmteco |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| Castor | Claymont, DE | eClinical Trial Software |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Amarin | Bridgewater, NJ | Small Molecules |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| Esper Therapeutics | , | Shut down 2016 |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| , | Shut down Oct 2025 | |
| SIRGA Advanced Biopharma | , | Appears defunct |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| , | Website down Dec 2025 - Jun 2026 | |
| Prommune | , | |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Sinotherapeutics | Shanghai, China | Generics |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| VasoNova | , | Acquired by Teleflex Medical |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| SoftGenetics | State College, PA | Software for genetic analysis |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| Panacos | , | Believe they are inactive |
| Turku Bioscience | Turku, Finland | Research Services |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| CardioEphEx | , | Shut down Dec 2020 |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| Novotech | Bangkok, Thailand | Clinical Research |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| Abpro | Burlington, MA | Antibodies |
| Noble | Orlando, FL | Auto-injector Trainers |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| NextPharma | London, UK | Contract Research & Development |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| , | Seems inactive Jan 2026 | |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Lindus Health | London, UK | CRO |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| LipimetiX Development | , | Website gone, Jan 2020 |
| DxTerity | Torrance, CA | Genomic Testing |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| GTX Medical | , | Renamed ONWARD |
| NeuroVia | , | Shut down 2019 |
| MeDiNova Research | , | Now part of Accelacare |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| Ablacon | , | Shut down Mar 2024 |
| TB-Stopper | , | Website hijacked Oct 2020 |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Totient | , | Acquired by Absci, Jul 2021 |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| Purdue Pharma | Wilson, NC | Small Molecules |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| Allergenics Inc | , | Closed Mar 2007 |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Green Cross | , | Renamed GC Pharma |
| Avenir Pharma | , | No longer active |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Sinobioway | , | |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Oak BioSciences | , | Shut down Nov 2024 |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| Sepiatec | Berlin, Germany | Separation Systems |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| , | Website down May 2025 - Dec 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| GeneDx | Gaithersburg, MD | Genetic Data |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Greenstone Biosciences | Palo Alto, CA | |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Lab901 | , | Bought by Agilent |
| Rho | Durham, NC | Clinical Research |
| Kesios Therapeutics | , | Closed down according to investors |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| , | Website down Jan 2026 - Mar 2026 | |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| PhotoThera | , | Ceased operations Dec 2012 |
| Akermin | , | Closed |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| , | Website down, CEO gone Apr 2026 | |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| CRI | , | Now BiomericsATL |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| Heritage Pharmaceuticals | , | Part of Emcure |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Theranostech | , | Renamed Sandia Biotech |
| CranioVation | , | Shut down Jan 2022 |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| Cherry Biotech | Paris, France | Organoid Culture |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Algenix | , | MN Business revoked, Mar 2004 |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| , | Acquired by Bruker, May 2024, €870M | |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| Acrongenomics | , | No info since 2013, seems gone |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| EDAP Technomed | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Alt Bioscience | , | Now PDx Biotech |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| , | Website down Aug 2025 - Jan 2026 | |
| Envision Genomics | , | Website gone Nov 2019 |
| Hygtia Therapeutics | , | |
| , | Acquired by Uniphar | |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Amphora Medical | , | Shut down May 2019 |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| ID Pharma | , | Acquired by I'rom Group |
| Stryker | San Jose, CA | Medical Devices |
| Heart Tronics | , | Effectively defunct after scandal |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Ossis | , | 3D-printed orthopedic implants |
| Proteorex | , | Gone Nov 2017 |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| SilaGene | , | Gone |
| Viropro | , | Bankrupt 2015 |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Kiecana Clinical Research | , | Now KCR |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| , | Website down Oct 2025 - Feb 2026 | |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| Biotest Labs | , | Acquired by/Merged with Steris |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| Biotrin International | , | Renamed Diasorin? |
| Quanticate | Raleigh, NC | Clinical Research |
| Gen-probe | , | Acquired by Hologic 2012 |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Nuvik Therapeutics | , | No website, very little info |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| CTC | Uppsala, Sweden | Clinical Site Network |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| Blade Therapeutics | , | Shut down Dec 2022 |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| Glen Research | Sterling, VA | Oligos |
| Genyous Biomedical International | , | Presumed Gone |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Rheos Medicines | , | Shut down Dec 2022 |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Spring Discovery | , | Renamed Spring Science |
| Adela | Toronto, ON | Liquid Biopsy |
| , | Renamed Virchow | |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| tte laboratories | , | Acquired by Transcat |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| Bioventus | Durham, NC | Orthobiologics |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Helix3 | Morrisville, NC | Contract Research Lab |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| Dornier MedTech | Rome, Italy | Urology Devices |
| AssureRx | , | Renamed Assurex Health |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| TRIFARMA | Rozzano, Italy | APIs |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| bioMerieux | Durham, NC | Diagnostics |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| Azopharma | , | Bankrupt, Apr 2010 |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Chesapeake Biological Labs | , | Now known as Cangene |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Norganoid | Macclesfield, UK | Organoid Technology |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| , | No info 2019 - Mar 2026 | |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| Boston Scientific | Spencer, IN | Medical Devices |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| , | Website down Jan 2026 - May 2026 | |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Texcell | Frederick, MD | Contract Research |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| Alte Biosciences | , | Gone, Apr 2016? |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| Raytone Bio | , | |
| Protelight Pharmaceuticals | Jiangyin, China | Peptide and Small Molecules Therapies |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Biotix | San Diego, CA | Lab Consumables |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| , | Acquired by Eclipsebio, Jan 2026 | |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| Akrivis Technologies | , | Gone Jun 2021 |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| SL Pharma Labs | , | Website gone May 2018 |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Mednoxa | , | Website gone Jan 2020 |
| Wheaton | , | Renamed DWK Life Sciences |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Singulex | , | Shut down Jun 2019 |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Lavipharm | Peania, Greece | Small molecules |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| 2 Bridge | Zoersel, Belgium | Consulting |
| Synomics | , | Now Smithers Pharma Services |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| CombiGene | , | Stopped research Jan 2025 |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Organix | Woburn, MA | Contract Research & Development |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| Modern Biosciences | , | Renamed Istisso |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| Orros Therapeutics | , | gone 2018 |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| Peplin | , | Acquired by Leo Pharma 2009 |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| BioWa | , | Part of Kyowa Kirin Group |
| Jet Life Sciences | Hyderabad, India | APIs |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Duality Biologics | Shanghai, China | ADCs |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| Molecular Detection Inc | , | Gone 2016 |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| eZono | Jena, Germany | Virtual Needle Guidance |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| Genomica | , | Shut down Sep 2022 |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| Apalexo Biotechnologie | , | No info, probably gone |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| Platelet BioGenesis | , | renamed PlateletBio |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Molecular Throughput | , | Rebranded as mtibio |
| Almac | Penicuik, UK | Pharmaceutical Services |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| BioMap | Palo Alto, CA | AI Models |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| RION | Rochester, MN | Exosome Therapeutics |
| AxoGlia Therapeutics | , | Ran out of money |
| Novitium Pharma | East Windsor, NJ | Generics |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Roche | Tucson, AZ | Diagnostics |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| , | Acquired by Hologic, Jan 2025, $350M | |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Medelis | Ypres, Belgium | Clinical Research |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| CytoMol (2) | , | SF-based, Looks gone |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Daré Bioscience | San Diego, CA | Women's Health |
| Mithridion | , | Website Gone, Company appears to be as well |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| Accellacare | Hickory, NC | Clinical Research |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| Gentian USA | Moss, Norway | IVD Products |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| BiomerTechnology | , | Ancient website, never registered in CA |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| EpiFinder | , | Gone May 2025 |
| Viwit | Shanghai, China | APIs, Formulation |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Therabest | Seoul, Korea | iPSC |
| Virscio | New Haven, CT | Contract Research & Consulting |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Altus Biologics | , | Vertex Subsidiary |
| Innogenix | Amityville, NY | Generics |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Macusight | , | Effectively acquired by Santen, 2008 |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Novarad | Provo, UT | Imaging Software and Technology |
| Pivotal BioSciences | , | Shut down late 2018 |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Alumis | South SF, CA | Autoimmune Treatments |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| PX Biosolutions | , | Gone |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| UMN Pharma | , | Liquidating Apr 2025 |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Appili Therapeutics | Halifax, NS | Small molecule |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| Norac Pharma | Azusa, CA | API Manufacturing |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| AbGenomics | , | Renamed Altrubio |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| Holloway America | Springfield, MO | Vessels, Tanks |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| Western States Biopharmaceuticals | , | Website Taken Over |
| Sarstedt | Nümbrecht, Germany | Lab products |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| , | Website down Oct 2025 - Dec 2025 | |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| LyoGo | , | Website gone, all employees gone |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| Lipid Genomics | , | Seems unserious |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Viva Biotech | Shanghai , China | Contract Research |
| , | Website down Oct 2025 - Feb 2026 | |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Genlantis | , | Acquired by AMSBIO |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Eleven P15 | , | Shut down |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Microfluidics | Westwood, MA | High shear fluid processors |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| XBiotech | Austin, TX | Antibody Therapy |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Regenica Biosciences | , | Gone Nov 2020 |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| , | Renamed Transcend, Feb 2022 | |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| , | Renamed Cyaris, Apr 2026 | |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Ergomed | Moscow, Russia | Clinical Research |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Veeva Systems | Radnor, PA | Life Science Software |
| hVIVO | London, UK | Viral Services |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Vanquish Oncology | , | No news 2015-2021 |
| Mojave Therapeutics | , | Gone |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| GeoVax | Smyrna, GA | Vaccines |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| PredictImmune | , | Shut down Nov 2023 |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| , | No news 2019 - Apr 2026 | |
| preclinics | Parma, Italy | Contract Research |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Strides Arcolab | , | Now just Strides |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Abbott | Altavista, VA | Nutrition |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| Indexus Biomedical | , | Shut down 2018 |
| Mentrik Biotech | , | Gone |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| ADS Biotechnology | , | Bankrupt 2014 |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| AltaRex | , | Gone |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| MedShape | , | Acquired by DJO, Apr 2021 |
| yuFlu | , | No website, no info Feb 2021 |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| Glenmark | Mumbai, India | Generic Small Molecules |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| , | Website down Dec 2025 - Mar 2026 | |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| , | Website down Jun 2025 - Dec 2025 | |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Doer Biologics | Hangzhou, China | Biologics |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| Cholestech | , | Now Alere |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Accellacare | Bristol, TN | Clinical Research |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Lavipharm | Paris, France | Small molecules |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| Genitope | , | Wound Down |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| , | Acquired by Tecan, Aug 2021 | |
| DDL | Eden Prairie, MN | Device Testing |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| , | Website down Dec 2025 | |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| FluoroPharma | , | Shell Company |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Dante Labs | , | Seems to be Dante Genomics now |
| , | Acquired by Sun Pharma, May 2025 | |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| AmProtein | , | Presumed Gone |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| Medicure | Holetown, Barbados | Small Molecule |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| Prokarium | London, UK | Oral Vaccines |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| FemtoVox | , | |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| Repco Development Technologies | , | Renamed 3Dispense |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| Lung LLC | , | Renamed Lung Biotechnology |
| , | Renamed Peritia, Jan 2026 | |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Kivu Bioscience | San Francisco, CA | ADCs |
| Sharp | Hamont-Achel, Belgium | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| FHC | Bowdoin, ME | Medical Devices |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Siga | Corvallis, OR | Small Molecules |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| BioMS Medical | , | Gone? |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| , | Closed June 2024 | |
| Ovation.io | Portland, ME | LIMS |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Novacea | , | Bought by Transcept |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Dexcom | San Diego, CA | Glucose Monitors |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| Meristem Therapeutics | , | Defunct |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| GNA Biosolutions | , | Now part of HP Health |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Phoresa | , | Shut down Mar 2018 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| IvWatch | Newport News, VA | IV infiltration detection |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| Celerion | Belfast, UK | Clinical Research |
| Delpor | Brisbane, CA | Drug Delivery System |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Protein Polymer Technologies | , | Basically Gone |
| Qurasense | , | Renamed Qvin |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| YMC Process Technologies | Devens, MA | Purification Technology |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| Accellacare | Ames, IA | Clinical Research |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| TherOptix | , | No website Oct 2021 - May 2023 |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Molecular Sensing | , | Business revoked Aug 2019 |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| HeartVista | , | Renamed Vista.ai |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| Pinnaxis | Noida, India | Pharmacovigilance |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| Peritia | Morrisville, NC | Consulting |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| InteRNA Technologies | , | Shut down Mar 2023 |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Epigenetix | , | No annual report filed 2013-2019 |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| EyeCyte | , | Gone 2014 |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| Cellink | Kyoto, Japan | Bioprinting |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Evonik Industries | Essen, Germany | API Manufacturing |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| Pierce | , | Part of Thermo Fisher |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| Gentegra | , | Part of IntegenX |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| American Stem Cell | , | Changed name to Targazyme |
| , | Website down Jul 2025 - Jan 2026 | |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Adams Clinical | Watertown, MA | Clinical Facility |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Cytochroma | , | Acquired by Opko Health |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| ViThera Pharmaceuticals | , | Gone 2017 |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| Patrin Pharma | Skokie, IL | Generics |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Delpharm | Lille, France | Contract Manufacturing |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| Molsid | Lyon, France | Fluorogenic Probes |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| bespark*bio | Vienna, Austria | Consulting |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| BHR Pharma | , | Subsidiary of Besins |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| NTC | Milan, Italy | Generics |
| Corza Medical | Somerset, UK | Surgical Devices |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Itero Biopharmaceuticals | , | Website Gone |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| algorithmRx | , | Now Venebio |
| Forge Biologics | Grove City, OH | Biologics |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| CanBas | Shizuoka, Japan | Small Molecules |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Axplora | Chennai, India | API manufacturing |
| , | Pivoted to blockchain, Sep 2025 | |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| Atugen | , | Acquired by SR Pharma 2005 |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Cerimon | , | Gone |
| Prescos | , | Shut down Feb 2014 |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| SCOLR Pharma | , | Closed Mar 2013 |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| AntiOp | , | Tech sold Jun 2015 |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| Norgine | Vienna, Austria | Specialty Pharma |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Lung Bioengineering | , | Part of United Therapeutics |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| VieVax | , | Gone Jan 2007 |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Genometry | , | Shut down Dec 2019 |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| , | Company gone Nov 2023, website taken by a game | |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| , | Winding down Apr 2026 | |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| KynderMed | , | Renamed Prena |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| DLK Medical Technologies | Dallas, TX | OTC |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Lucena | , | Failed |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| BiVACOR | Houston, TX | Heart replacement |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Pion | Billerica, MA | Dissolution Data |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| PeriGen | Cary, NC | Perinatal Devices |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Serometrix | , | More of an aspiration than a company |
| MacuClear | , | Website gone Jan 2019 |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Renamed Numerion Labs, Oct 2025 | |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Warnex | , | Merged into DIAGNOS Inc |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Refined Diagnostics | Münster, Germany | Lasers |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| Berlex | , | Now Bayer |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| , | Part of Genesis Biotechnology Group | |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| NeuTec Pharma | , | Shut down 2010 |
| Nile Therapeutics | , | Merged with Capricor |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Nvelop Therapeutics | , | |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| Getinge | Mumbai, India | Medical Technology |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Rallybio | New Haven, CT | Therapeutics |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| BaseCure Therapeutics | , | |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| RenovoRx | Mountain View, CA | Catheters |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| , | Shut down 2024 | |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Lupin | Mumbai, India | Generics |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| Iconovo | Lund, Sweden | Inhalation Technology |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| ErVimmune | Lyon, France | Cancer Vaccines |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| Italchimici | , | Acquired by Recordati, May 2016 |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| , | Acquired by IQVIA | |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| Advanced Vision Science | , | |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
 |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| , | Website down Jul 2025 - Jan 2026 | |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Glysantis | , | Shut down Late 2020 |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Aytu BioScience | , | now Aytu BioPharma |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| , | Website down Oct 2025 - Feb 2026 | |
| Kuroki Consulting | , | Shut down 2020 |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Aitia | Cambridge, MA | Analytics |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| , | Website down Sep 2025 - Feb 2026 | |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Zai Lab | Cambridge, MA | Small Molecules |
| American Regent | Shirley, NY | Generics |
| Vision Medicines | , | Gone 2017 |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| COOL-BIO | , | Gone |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| ImmunoBiochem | , | No news 2018 -2023 |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| , | Website down Nov 2025 - Apr 2026 | |
| Createrna Science | Shanghai, China | Small Molecules |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| , | Renamed Until Labs, Oct 2025 | |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| OverT Bio | New York, NY | Cell Therapy |
| Sebra | Tucson, AZ | Tube Sealer |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| BioTeam | Middleton, MA | Scientific IT consulting |
| Leucid Bio | London, UK | Cell Therapy |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| PDL BioPharma | , | Shut down early 2021 |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| , | Shut Down Dec 2024 | |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Progenika | , | Bought by Grifols |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Phenoquest | , | Website gone, Oct 2015 |
| Veeva Systems | Shanghai, China | Life Science Software |
| Stemnovate | Cambridge, UK | Research Cells |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| , | Liquidation, Jun 2025 | |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| Axplora | Raubling, Germany | API CDMO |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Haini Pharmaceutical | Shanghai, China | Generics |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Tella | , | Website down May 2023 - Dec 2023 |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Cadex Genomics | , | Shut down Jul 2024 |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| Western Biologics | , | Dissolved, 1998 |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| Accellix | Jerusalem, Israel | On-demand Assays |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| Zumutor Biologics | Bangalore, India | Biologics |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| PsiOxus Therapeutics | , | |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Nexus BioPharma | , | No news 2017-2022 |
| Intellirod Spine | , | Sold Assets late 2020 |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| Faze Medicines | , | Shutting down Nov 2022 |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| Aves Labs | , | Now part of Antibodies Inc |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| , | Website down Nov 2025 - Apr 2026 | |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| Nanosonics | Sydney, Australia | Ultrasound |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| Synthace | London, UK | Development Software |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Chrysalis | Burlington, MA | GMP Space |
| Compass Biotech | , | Defunct |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Synostics | , | Gone 2014 |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| , | Website gone Feb 2026 | |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| Weatherden | London, UK | Clinical Consulting |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| Androclus Therapeutics | , | Closed, May 2007 |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| , | Subsumed into Synoptics | |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Leukosight | , | Gone, website is online pharmacy now |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Medpace | Cincinnati, OH | Clinical Research |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| JCL Bioassay | , | Renamed CMIC |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| BioLegacy Research | San Diego, CA | Contract Research |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Proteologics | , | Apparently Gone |
| Avomeen | , | Acquired by Element, Mar 2021 |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| imarc | , | Acquired by Avania, Jun 2021 |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Beacle | , | Founder gone, no info |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| Neuronax | , | Renamed Axoltis Pharma |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Evofem Biosciences | San Diego, CA | Women's health |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| M3 Wake Research | Encino, CA | Clinical Research |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Biorelate | Manchester, UK | AI Data Curation |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| , | Acquired by Canoa, Aug 2019 | |
| Protypia | , | |
| Zenosense | , | No website, shell company Nov 2020 |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| , | Website down Nov 2025 - Apr 2026 | |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Starkey | Eden Prairie, MN | Hearing Aids |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Pharmadax | New Taipei City, Taiwan | Generics |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| , | Part of SBO Hearing, Feb 2026 | |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Rx3 | , | Now Trius Therapeutics |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| MabPrex | , | Out of business, 2016 |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Quench Bio | , | Wound down Mar 2021 |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Coldstream Laboratories | , | Bought by Piramal |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Mabimmune | , | Merged with Neurimmune |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Mendelian | London, UK | Rare Disease Diagnosis |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Promedior | , | Acquired by Roche, Feb 2020 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| , | Renamed Helus Pharma, Jan 2026 | |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| Triangle Insights Group | Durham, NC | Consulting |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| SVA | Madison, WI | Biotechnology Management Consulting |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Ikotech | , | Closed Dec 2015 |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| Instapath | Houston , TX | Automated Digital Pathology |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Trine Pharmaceuticals | , | Closed 2008 |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Coferon | , | Renamed BlinkBio |
| , | Renamed Pixl.bio, Nov 2025 | |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| Retroject | , | Seems gone |
| , | Website down Jun 2025 - Dec 2025 | |
| Padagis | Allegan, MI | Generics |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Accellacare | Salisbury, NC | Clinical Research |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| MDQuest | , | Website Down Feb 2025 |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| ArKal Medical | , | Gone 2012 |
| , | Renamed Ensera, Oct 2025 | |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| , | Merged with Nova Biomedical | |
| MiRus | Marietta, GA | Spine Implants |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Signalife | , | Renamed Heart Tronics |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| CellCarta | Montréal, QC | Clinical Research |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Anthra Pharmaceutical | , | Gone |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| , | Liquidating Jan 2026 | |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| Alliances Catalyst | , | Liquidated |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Altasciences | Montréal, QC | Contract Research |
| Piramal | Riverview, MI | CDMO |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| Nanostream | , | Closed Mar 2008 |
| Maroon Biotech | , | Gone Sep 2010 |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| Launchpad Therapeutics | , | |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| SunMed | , | Renamed AirLife |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Genera Medix | , | Apparently sold all products |
| Xact Medical | , | Website down Mar 2024 |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| Vaxart | South SF, CA | Oral Vaccines |
| Ebewe Pharma | , | Now Sandoz |
| Lannett | Trevose, PA | Generic Small Molecules |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| VasculoMedics | , | Gone 2019 |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Zai Lab | Shanghai, China | Small Molecules |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Moon Surgical | Paris, France | Robotic Surgery System |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Anchen | , | Bought by Par Pharmaceutical |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| , | Website down Jan 2026 - May 2026 | |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| Apic Bio | , | Shut down Jan 2024 |
| Fairway Medical Technologies | , | Website gone |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| BioPhyZica | , | Gone 2016 |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Advarra | Columbia, MD | Regulatory Consulting |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| NeoVentures | London, ON | Custom Aptamers |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Grove Instruments | , | Shut Down June 2017 |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Biomatters | , | Renamed Geneious |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| , | Website down Oct 2025 - Feb 2026 | |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| Java Clinical | , | Website gone Jun 2019 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Almirall | Barcelona, Spain | Small Molecules |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Bausch Health | Laval, QC | Small Molecules |
| Mattson Jack | , | Now Kantar Health 2009 |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| Cytiva | Amersham, UK | Medical Devices |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| Cam Med | , | Renamed Qlibrium |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Quell Therapeutics | London, UK | Treg cell therapies |
| , | Website down Jan 2026 - May 2026 | |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| EmerVax | , | Renamed Circurna |
| Mott | Farmington, CT | HPLC system components, Filtration |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| , | Website down Jun 2025 - Dec 2025 | |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| White Biotech Solutions | , | Shut Down 2019 |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Divergence | , | Bought by Monsanto |
| Lumanity | London, UK | Consulting |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Zai Lab | Beijing, China | Small Molecules |
| Pathens | , | Website hijacked Sep 2020 |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Saghmos Therapeutics | , | |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Niagara Biosciences | , | No info, Aug 2022 |
| , | Website down Jul 2025 - Dec 2025 | |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Novotech | Shanghai, China | Clinical Research |
| , | Renamed MindWalk, Sep 2025 | |
| Ximedica | San Francisco, CA | Medical Device Services |
| Origen Therapeutics | , | Gone |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Alife | San Francisco, CA | AI-powered IVF |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Labopharm | , | Bought by Paladin 2011 |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Pathnostics | Irvine, CA | Diagnostics |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Afferon | , | Gone, no info |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| Neuroptix | , | Renamed Cognoptix |
| Active Implants | , | Renamed NUsurface |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Cytomatrix | , | Gone, Jun 2013 |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Onorach | Dundee, UK | Clinical Trial Management |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| , | Website down Sep 2025 - Dec 2025 | |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| Ventris Medical | Newport Beach, CA | Tissues |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Life Analytics Group | , | Gone |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| AbBaltis | Kent, UK | Plasmas & Sera |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Breathometer | , | Product didn’t work, pivoted |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| Tecnimede | Lisbon, Portugal | Generics |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| , | Renamed Silthera, Apr 2026 | |
| Gene Sciences | , | Shut Down Jul 2019 |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| BinaryBio | , | Out of business Jul 2015 |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Omnimmune | , | Shell company, trademark abandoned |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| ACROBiosystems | Basel, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| EcoSurg | , | Shut Down May 2017 |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Senseonics | Germantown, MD | Medical Devices |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| , | part of ElevateBio; fka LifeEDIT | |
| Stemnovate | Cambridge, UK | Research Cells |
| Mediso | Budapest, Hungary | Medical Imaging |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Metrics Inc | , | Renamed Metrics Contract Services |
| iTherapeutics | , | Doubt they do anything |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Biotox Sciences | , | Renamed BTS Research |
| Genuiti Therapeutics | , | |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Clarivate | London, UK | Vascularized organoids |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| CoRegen | Aspen, CO | Genetically Engineered T Reg Cells |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Nanovelos | , | Subsumed into Nanogroup |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Remora Therapeutics | , | Shut down 2021 |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Dharma Therapeutics | , | Gone, 2013 |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Beardsworth | , | Bought by TFS International 2013 |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Baxter | Singapore, Singapore | Medication Delivery |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| Geron | Foster City, CA | Small Molecule |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| Integer | El Paso, TX | Medical & Surgical Devices |
| , | Website down Aug 2025 - Jan 2026 | |
| Immerge BioTherapeutics | , | Founded 2000 |
| Axplora | Mourenx, France | API manufacturing |
| Luye Pharma | Shanghai, China | Small Molecules |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| MJ Biopharma | Mumbai, India | Generics |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Pharmion | , | Acquired by Celgene 2007 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Selten Pharma | , | Gone 2017 |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| DiAthegen | , | Website Gone Oct 2015 |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Celavie Biosciences | , | Shut down Mar 2024 |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Attenuon | , | Now Tactic |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| , | Website down Jan 2026 - May 2026 | |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Tecomet | Wilmington, MA | Implant Components |
| Syneos Health | Newtown, PA | Clinical Development |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| Stada | Vršac, Serbia | Generics |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| AbbVie | Waco, TX | Contract Manufacturing |
| Barc Lab | , | Renamed Cerba Research |
| NeuroVasx | , | No website May 2019, founded 1997 |
| iThemba Pharmaceuticals | , | No information |
| Pharmos | , | Gone |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Vascular Genesis | , | Website gone Aug 2022 |
| Enterey | Irvine, CA | Life Science Consulting |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| F2G | Cheshire, UK | Antifungals |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| Boston Scientific | Cork, Ireland | Medical Devices |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Chanelle Pharma | London, UK | Generics |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| , | Renamed Kyntra Bio, Jan 2026 | |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| , | Now part of Sanisure, Jun 2026 | |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Clarapath | Hawthorne, NY | Pathology Device |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| , | Website down Jun 2025 - Dec 2025 | |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Septerna | South SF, CA | GPCR Drug Discovery |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Takara Bio USA | San Jose, CA | Lab products |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Kulira Technologies | , | Website Gone Oct 2016 |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| K2M | , | Acquired by Stryker, Nov 2018 |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| AAVLife | , | Renamed Annapurna |
| Tethys Bioscience | , | Shut Down, late 2013 |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| CytoLogix | , | Gone, Sep 2012 |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| G6 Spine | , | Gone 2017 |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| OBDURO Biotechnologies | , | never a registered CA business |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Clontech | , | Now Takara Bio |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Supeira | , | Website gone Mar 2023 |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| , | Website down Oct 2025 - Feb 2026 | |
| Zyomyx | , | Closed as of 2014 |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| , | Shut down late 2025 | |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| Carver Biosciences | , | |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| Quentis Therapeutics | , | Shut down late 2020 |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| SDIX | Newark, DE | Diagnostics |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| Covaris | Woburn, MA | DNA Sample Prep |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Xtuit | , | Gone Jul 2018 |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Minimus Spine | , | Only real employee now full-time at another company |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Effipharma | , | Marked as closed by Google |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| InCytu | , | Website gone Jul 2015 |
| , | Assets Acquired by Klotho, Sep 2025 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| Soluble Systems | , | Renamed Solsys Medical |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| , | No news 2018 - Sep 2025 | |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Viravaxx | , | |
| Terpenoid Therapeutics | , | Gone |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| , | Liquidating, Mar 2025 | |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| , | Pivoted to Crypto, Oct 2025 | |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| Hana Biosciences | , | Now Talon Therapeutics |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| , | Website down Oct 2025 - Jan 2026 | |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Ezose Sciences | , | Rebranded as S-bio |
| Adynxx | , | Website taken over Sep 2020 |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Roslin Cells | , | Renamed RoslinCT |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| TR Biosurgical | , | Website Taken Over |
| EndoStim | , | Shut down Jan 2020 |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| LENSAR | Orlando, FL | Cataract Laser |
| TheoremDx | , | Bankrupt Feb 2020 |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Plexision | Pittsburgh, PA | Diagnostics |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Aliri | Loos, France | Contract Mass Spec |
| Primevera Therapeutics | , | |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| NascaCell | , | German Aptamer company, not sure of fate |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Nascent Biologics | , | Changed to Nascent Biotech |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| Gentell | Yardley, PA | Wound Care |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| , | No news 2017 - Apr 2026 | |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| Getinge | Getinge, Sweden | Medical Technology |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Abviva | , | Gone, 2008 |
| , | Acquired by Altivera Medical, Mar 2026 | |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Allenex | , | Bought by CareDx, Apri 2016 |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Samsara Sciences | , | Shut Down Mar 2020 |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| , | Website down Sep 2025 - Dec 2025 | |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Acumed | Hillsboro, OR | Medical Implants |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Supratek Pharma | , | Website gone Sep 2017 |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Innomab | , | Gone 2017 |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| Biocorp | Issoire, France | Medical Devices |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| , | No news Jun 2021 - Jan 2026 | |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| CeQur | Greenville, SC | Insulin pump |
| NeuroNano Pharma | , | Gone 2018 |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| Stiefel | , | Acquired by GSK |
| Lusis | Hayward, CA | Diagnostics |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| , | Shut down Feb 2026 | |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Align Technology | Tempe, AZ | Teeth alignment |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| Vivamer | , | Shut down, Jul 2015 |
| AmplifyBio | , | Shut down Apr 2025 |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Cato Research | , | Renamed CATO-SMS |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Anazen Diagnostics | , | Part of Cardiox |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| TargeGen | , | Bought by Sanofi 2010 |
| numares | Regensburg, Germany | Clinical Diagnostics |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Compucyte | , | Sold Assets to Thor Labs |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Orthologic | , | Now Capstone Therapeutics |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| Curium | , | Dissolved, Mar 2015 |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Heragen | , | Gone |
| OperaCRO | , | Now part of Tigermed |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Getinge | Englewood, CO | Medical Technology |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| , | Acquired by InformedDNA, Mar 2025 | |
| nference | Cambridge, MA | Clinical AI |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Epigen | , | Renamed Egenix, 2002 |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Zars Pharma | , | Acquired by NuVo Research |
| Procertus | , | Website Gone, Apr 2016 |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Pharmaron | Ningbo, China | R&D Services |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Optherion | , | Sold Assets, Still Exists |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| Pharminox | , | Website gone, Aug 2017 |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| Diploid Genomics | , | |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Veramed | London, UK | Biostatistics and programming services |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Vivifi Life Sciences | Bangalore, India | Generics |
| Sanofi | Haverhill, UK | Small Molecules |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| Nuvation Bio | New York, NY | Oncology Treatments |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Sonosine | Kidlington, UK | Medical Imaging |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Lifebit | London, UK | Genetic Data Analysis |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Capsigen | Vancouver, WA | AAV Vectors |
| IGF Oncology | , | Shut down 2022 |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| , | Website down Jan 2026 - May 2026 | |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| Calibrant | , | Closed |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| , | Website down Jan 2026 - May 2026 | |
| Oncology Clinical Research | , | Gone |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| Vanadis Laboratories | , | Gone 2018 |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| CovX Research | , | Bought by Pfizer |
| LightMed | , | |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| Iquum | , | Acquired by Roche, Apr 2014 |
| , | Website taken over May 2026 | |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| VitaCyte | Indianapolis, IN | Collagenase |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| , | Website down Dec 2025 - Apr 2026 | |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| NeoPharm | , | Merged with Insys Therapeutics |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Terapio | , | Website Gone, Sep 2020 |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Twistnostics | , | Renamed Scanogen |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Santen | Osaka, Japan | Ophthalmics |
| , | Acquired by Sebia, Sep 2024 | |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| NetBio | , | Renamed ANDE |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| Eurand | , | Now Aptalis |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| , | Website down Sep 2025 - Dec 2025 | |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| EndoSphere | , | Gone pre-2011 |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| Grunenthal | Quito, Ecuador | Small molecules |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Genecare | , | Gone |
| , | Website down May 2025 - Nov 2025 | |
| DDL | Edison, NJ | Device Testing |
| Recopharma | , | Seems gone |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Kereos | , | Seems gone |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Actome | Freiburg, Germany | Protein Quantification |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Biopar | , | Gone? |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Promosome | , | Gone |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Epigenesis Pharmaceuticals | , | Gone |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Batu Biologics | , | Gone 2019? |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| , | Website down Jan 2026 - May 2026 | |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| AmCell Biosciences | , | Website gone Apr 2021 |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Affitech | , | Gone |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| V-gene | , | Website gone, Aug 2017 |
| ImmuRx | , | Gone, not sure what happened |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| HawkCell | Lyon, France | MRI Research Technology |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| Integer | Plano, TX | Medical & Surgical Devices |
| , | Renamed Ribonexus, Nov 2021 | |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Clinical Microbiomics | , | Merged into cmbio |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| , | Website down Oct 2025 - Jan 2026 | |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| Isis Biopolymer | , | Website taken over |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| Protein Design Labs | , | Renamed PDL Biopharma |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Summation Bio | , | Shut down May 2023 |
| , | Crypto Pivot, Nov 2025 | |
| Rox Medical | , | Gone 2019 |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| KALA BIO | Arlington, MA | Drug Delivery |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Profil | Neuss, Germany | Clinical Research Services |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Codon Devices | , | Closed Apr 2009 |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| Talee Bio | , | Renamed Spirovant Sciences |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| , | Website down Jul 2025 - Nov 2025 | |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| NorthLinks Bio | , | |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Proteonomix | , | Shell Company |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| DiaGenic | , | Switched to energy sector |
| Ecopharm | , | Website down Feb 2021 |
| Sinovac Biotech | Beijing, China | Vaccines |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| PACT Pharma | , | Shut down Sep 2023 |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| X-Rx | , | Shut down Jun 2020 |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Oxis International | , | Renamed GT Biopharma |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Kallyope | New York, NY | Gut-brain axis focus |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Quanticate | Hitchin, UK | Clinical Research |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| EMD Serono | Boston, MA | Biologics |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| Inductive Bio | Virtual, US | Compound Optimization |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Abcellute | , | Dissolved, Sep 2016 |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| STB Lifesaving Technologies | , | Website gone |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| Sanovel | Istanbul, Turkey | Generics |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| Atanse | , | Website gone, May 2018 |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| TG Therapeutics | Morrisville, NC | Biologics |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| ASIT Biotech | , | Renamed DMS Imaging |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Optime Therapeutics | , | Acquired by Lippomix |
| Resilience | San Diego, CA | Biomanufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| Root Lines Technology | , | Renamed Samabriva |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| ZyGEM | , | Renamed MicroGEM |
| Vernay | Griffin, GA | Fluid Control Solutions |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| OmniBiome Therapeutics | , | Gone 2014? |
| Piramal | Lexington, KY | CDMO |
| ICU Medical | San Clemente, CA | Disposable medical products |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Pharma Medica | Toronto, ON | Clinical Services |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| Cerimon Pharmaceuticals | , | Gone |
| , | Renamed EarliPoint Health, Oct 2025 | |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Bayer | Bitterfeld, Germany | Small Molecules |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| , | Website down Jul 2025 - Jan 2026 | |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Belyntic | Berlin, Germany | Immunotherapies |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Genetic Technologies Group | , | Renamed geneType |
| Abbott | Singapore, Singapore | Diagnostics |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Healogix | Doylestown, PA | Consulting |
| , | Website down Aug 2025 - Jan 2026 | |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Valneva | Lyon, France | Antibody Discovery |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| , | Renamed Alethio Therapeutics | |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| Northfield Laboratories | , | Bankrupt 2009 |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Arxspan | , | Renamed SciY |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Cymbiotics | , | Gone 2019-2020 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| XaTek | , | No news 2021 - Feb 2025 |
| Abselion | Cambridge, MA | Biologics Quantification |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Immunosyn | , | Charged with Securities Fraud |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| Expression Patholgy | , | Now OncoPlexDx |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Allogene Therapeutics | South SF, CA | CAR-T |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Pharsight | , | Merged with Tripos to become Certara |
| Proteotech | , | Website gone Jul 2015 |
| Antisoma | , | Became investment company |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| Vectura | , | |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| , | No news 2021 - Sep 2025 | |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| Alphatec Spine | , | Renamed Atec Spine |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Duramed | , | Acquired by Barr Labs 2001 |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| InnoCare | Shanghai, China | Cancer Treatments |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| OFD Biopharma | Albany, OR | Lyophilization |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Maxivax | , | Renamed Release Therapeutics |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| BionX Medical | , | Acquired by Ottobock |
| , | Website down Oct 2025 - Jan 2026 | |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Arzeda | Seattle, WA | Computation protein design |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Gentel Bio | , | Ceased Operations 2012 |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| Metrochem | Hyderabad , India | APIs |
| , | Acquired by mining company; fka Anew Medical | |
| Conformis | , | |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| Nova Biomedical | Norwood, MA | Lab instruments |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| , | Website down Jan 2026 - May 2026 | |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| GemacBio | , | Renamed PolyNeuroS |
| Diatos | , | No website, founded 1999 |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| Hybrigenics Services | , | Renamed ATON Group |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| Targovax | , | Renamed Circio, Apr 2023 |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Cognosci | , | CEO has another job, doesn't seem serious |
| NovoLipid | , | Website Gone |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Stago | Franconville, France | Diagnostics |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| MiniMed | Northridge, CA | Diabetes Management |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| NIOX | Morrisville, NC | Asthma management device |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Wacker | Munich, Germany | Polymers, Resins |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Micell Technologies | , | Seems shut down 2019 |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Ansh Labs | Webster, TX | Diagnostics Products |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Ankon Technologies | Wuhan, China | Medical Devices |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Tolmar | Fort Collins, CO | Small Molecules |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Protalex | , | Failed 2018, shell |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Delta-Vir | , | Website down Mar 2023 |
| Thyritope Biosciences | , | Closed Oct 2016 |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Getinge | Plewiska, Poland | Medical Technology |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| , | Merged with Vizgen, Oct 2024 | |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| ALTx Therapeutics | , | Small Molecule Therapies |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| Xcelthera | , | Shut down, Apr 2021 |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Sure Genomics | , | Gone 2014? |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Virvio | , | Gone Feb 2020 |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Chrysalis | Waltham, MA | GMP Space |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Oncodesign Services | Dijon, France | Preclinical services |
| inDNA Research Labs | , | Shut down 2015 |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Visitube | , | No website Mar 2020 |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Suvoda | Portland, OR | Clinical Trial Software |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Peptimmune | , | Liquidated 2011 |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| X7 Research | , | Website hijacked Feb 2025 |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| , | Shut down Jan 2025 | |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| , | No news Aug 2019 - Jan 2026 | |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Par Health | St. Louis, MO | Generics |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| NS Pharma | Paramus, NJ | Small Molecule |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Alacrity Biosciences | , | Gone post-2011 |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| RetiPharma | , | Dissolved Nov 2019 |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Life Couriers | Munich, Germany | Diagnostics |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Clinnex | Ahmedabad, India | Clinical Research |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| AstraZeneca | New Haven, CT | Biologics |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| PMG Research | , | Now Acellacare |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| NX Development | Lexington, KY | Brain Imaging |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| , | Gone 2023, website taken over by a designer | |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Korio | Doylestown, PA | RTSM Platform |
| Solano Pharmaceuticals | , | Website gone |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| Trophea | , | Liquidated, Dec 2019 |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| 4HF Biotec | Freiburg, Germany | Anti-cancer Treatments |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Alfasigma | Bologna, Italy | Small Molecules? |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| VALOS | Genova, Italy | Clinical Statistics |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Medrio | San Francisco, CA | Clinical Trial Software |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Isolagen | , | Reorganized as Fibrocell Science |
| Sensys Medical | , | Old company, no website, presumed defunct |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Niveus Medical | , | Closed Dec 2017 |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| , | Acquire by Savillex, Nov 2024 | |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| Formycon | Martinsried, Germany | Biosimilars |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| , | No news 2021 - Sep 2025 | |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| Lexogen | Vienna, Austria | RNA kits |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| CytoVera | , | Gone June 2017 |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| Uncover Therapeutics | , | |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Essential Pharma | Egham, UK | Generics |
| , | No news Jan 2021 - Jan 2026 | |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| SYNkinase | , | Shut down |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Celerion | Montreal, QC | Clinical Research |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Stelvio Oncology | , | Gone late 2019 |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Archimedes Vascular | Birmingham, | Hypertension Devices |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| AMR Bio | Brighton, UK | Antimicrobials |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Hemanext | Lexington, MA | Transfusion Technologies |
| Aspreva | , | Acquired by Vifor Pharma |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| TamuroBio | , | Shut Down Jun 2024 |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Clina Research | , | Website gone Jul 2023 |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| Clario | Philadelphia, PA | Clinical Services |
| Salvat | Madrid, Spain | Small Molecules |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Nido Surgical | , | Shut down Apr 2022 |
| , | Renamed Mobia Medical, Feb 2026 | |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| Limerick Bio | , | Gone 2011 |
| Neocis | Miami, FL | Dental Surgery Robots |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| Evocutis | , | Pivoted to investments |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| AngioChem | , | All employees gone, no info, presumed gone |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| Biophytis | Paris, France | Therapies for aging diseases |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Retroscreen Virology Group | , | Renamed hVIVO |
| , | Website down Sep 2025 - Feb 2026 | |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Coeptis | , | |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| Qlucore | Lund, Sweden | Visualization Software |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Ceptyr | , | Out of business 2012 |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| Resilience | Mississauga, ON | Biomanufacturing |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| Tangent Medical Systems | , | Closed |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Aerovance | , | Gone, don’t know where |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| , | Website messed up, single employee, Dec 2025 | |
| Recodagen | , | Gone Jun 2009 |
| Perlegen | , | No Site |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| MetaMol Theranostics | , | Gone |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Solvay | , | Bought by Abbott 2010 |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Novaliq | Cambridge, MA | Drug Delivery |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Skylit Medical | , | Renamed Clarify medical |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| , | Shut down Nov 2025 | |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Bionas Discovery | , | Website gone Jun 2018 |
| Acidophil | , | Gone late 2022 |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Mindshare Medical | , | Renamed RevealDx |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| Getinge | Rastatt, Germany | Medical Technology |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| TauTaTis | , | Shut down 2011 |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Avaxia Biologics | , | IP acquired by Circle33 |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Neurokos | , | Gone. No info |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Synthon | , | |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| Ribocept | , | Defunct |
| Instylla | Bedford, MA | Embolization treatment |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Echo | San Diego, CA | Microscopy |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Calico | South SF, CA | Aging treatments |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Loop Therapeutics | , | Shut down Jan 2021 |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| , | Pivoted to crypto Jan 2026 | |
| C/M/C Biologics | , | Now CMC Biologics |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| , | Acquired by Versiti, Jul 2023 | |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| CanSino Biologics | Tianjin, China | Vaccines |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| MacroPore | , | Gone |
| 1CellBio | , | Gone Jun 2019 |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Neose | , | Gone |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Zila | , | Bought by Tolmar, Jul 2009 |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Opsonix | , | Shut down May 2018 |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Flen Pharma | , | Now Flen Health |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| , | Website down May 2025 - Sep 2025 | |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| Perceptive | Nottingham, UK | Medical Imaging |
| , | Main person has four other jobs, Dec 2025 | |
| Piramal | Sellersville, PA | CDMO |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Alcon | Irvine, CA | Eye-Care Products |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| ERBC | Baugy, France | Non clinical CRO |
| Virtici | Seattle, WA | Product / Company Incubator |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Biodel | , | Merged with Albireo, Oct 2016 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| , | Website down Jan 2026 - May 2026 | |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| , | Website down Sep 2025 - Feb 2026 | |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| NuAire | Plymouth, MN | Lab Equipment |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| AMRI | , | Renamed Curia, Jul 2021 |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| Molecular Logix | , | Gone, Dec 2018 |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Sea Medical Systems | , | Gone |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| , | Acquired by AbbVie, Aug 2025 | |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| Madeira Therapeutics | , | Gone. No info |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| Natera | San Carlos, CA | Prenatal Testing |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Vernacare | Worksop, UK | Surgical Devices |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Progyny | New York, NY | IVF products |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| MabCo | , | Renamed Agenix |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| , | Renamed Fareon, Feb 2025 | |
| Mabcare Therapeutics | , | |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| BASF Bioservices | , | Exited business, Sep 2025? |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| Apollomics | Foster City, CA | Cancer medicines |
| CohBar | , | Shut down, late 2023 |
| AliveDx | Eysins, Switzerland | Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| SanBio BV | Uden, Netherlands | Antibodies |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| Gencove | New York, NY | Genome Sequencing |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Exelixis | Alameda, CA | Small Molecules |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Intrexon | , | Renamed Precigen |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Celula | , | Acquired by NeoSeq |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| OccuRx | , | Merged into Certa Therapeutics |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Panaxia | Lod, Israel | Medical Cannabis |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| NeoCura | Beijing, China | Personalized Vaccines |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| , | Acquired by Embecta, Mar 2026 | |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| AbX Biologics | , | Renamed Abveris |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Cedilla Therapeutics | , | Shut down May 2023 |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| , | Part of Greenpharma | |
| Healx | Cambridge, UK | AI Drug Discovery |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| VastBiome | , | Renamed PragmaBiome |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Piramal | Grangemouth, UK | CDMO |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| Novosis | , | Acquired by Acino, 2006 |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| , | Shut down Jul 2025 | |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| , | Acquired by Alcon, Sep 2025 | |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| , | Website down Dec 2025 - Apr 2026 | |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| BioConsulting International | , | Ancient website, presumed defunct |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| NK CellTech | Shanghai, China | Cell Therapies |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| ProPharma Group | Washington, DC | Consulting |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| mibe Arzneimittel | Brehna, Germany | Generics |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| , | Main employees gone for months as of Nov 2025 | |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| Celvive | , | No news from 2012-2020 |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| ReproSource | Marlborough, MA | Fertility Testing |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| Aerogen | Galway, Ireland | Nebulizers |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Piramal | Turbhe, India | CDMO |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| ZipBio | Seattle, WA | Compact Proteins |
| Avexa | , | Renamed Novita Healthcare |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| , | Website down Dec 2025 - Apr 2026 | |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| Bayer | Barcelona, Spain | Small Molecules |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| Aeson Therapeutics | , | Gone Mar 2006 |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Mediatech | , | Now Cellgro |
| MiniVax | , | Gone Jan 2016 |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| PNP Therapeutics | Birmingham, AL | Outlicensed sole product Sep 2021 |
| EPISONA | , | Gone Nov 2018 |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| Glenveigh Medical | , | Website down Sep 2024 |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Kirgen | Shanghai, China | Lab Supplies |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Concordia Healthcare | , | Now Concordia International |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Noucor Health | Barcelona, Spain | Small Molecules |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Caidya | Shanghai, China | Clinical Research Organization |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| Stat One | Morrisvile, NC | eClinical |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| Axxam | Milan, Italy | Drug discovery services |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Boston Scientific | Marlborough, MA | Medical Devices |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| LemnaGene | , | Acquired by Biolex 2005 |
| Fonar | Melville, NY | Upright MRI |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| CreaGen | Woburn, MA | Drug Discovery Services |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| BEAT BioTherapeutics | , | Closed 2017 |
| , | No news 2019 - Sep 2025 | |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Novotech | Sydney, Australia | Clinical Research |
| Axonia Medical | , | Gone 2015 |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| LivaNova | London, UK | Nerve stimulation therapy |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| VistaMed | , | |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| KAI Research | , | Acquired by Navitas Life Sciences |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| Affinimark Technologies | , | Gone |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Ribomic | Tokyo , Japan | Aptamers |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| , | Website down Jul 2025 - Dec 2025 | |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| ApoVax | , | Shut down Jul 2014 |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Champions Biotechnology | , | Now Champions Oncology |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| DxTech | , | Seems gone. No info Dec 2015 |
| FFE Therapeutics | , | Shut down Dec 2013 |
| Mousera | , | Renamed Vium |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| OxOnc Development | , | Website gone Apr 2018 |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| Orthofix International | Lewisville, TX | Medical Devices |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Quantificare | Biot, France | Medical Imaging |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| , | Website down Dec 2025 - Jun 2026 | |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Cromos Pharma | Portland, OR | Clinical Research |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| , | Acquired by GNI Group, Jun 2026 | |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Cellnovo | , | Bankrupt, Jul 2019 |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| Avam | Odessa, FL | Clinical Diagnostics |
| NEXGEL | Langhorne, PA | Hydrogels |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| ICN Pharmaceuticals | , | Now Valeant |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| Innerpulse | , | Gone maybe 2013 |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| , | Website down Jan 2026 - May 2026 | |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| , | Website taken over Mar 2026 | |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Createrna Science | Wuhan, China | Small Molecules |
| Advanced Peptides | , | No business filings since 2011 |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| Terumo Medical | Somerset, NJ | Medical Devices |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Roche | Burgess Hill, UK | Diagnostics |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| ECI Biotech | , | Gone 2016 |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| Medelis | Thompson's Station, TN | Clinical Research |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Pharmatrope | , | Absurd website 2020-2023 |
| Alxerion Biotech | , | Gone May 2021 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| Axplora | Shanghai, China | Purification Systems |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| CPI Global | , | Website gone Jun 2020 |
| , | Pivoted to food, Feb 2026 | |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Getinge | Fairfield , NJ | Medical Technology |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Veryan Medical | Horsham, UK | Helical Stent |
| Weatherwax | , | Renamed General Proximity |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Phase Forward | , | Bought by oracle |
| Hybrigenics | , | Renamed ATON |
| Catylix | , | Shut down Oct 2021 |
| LumaBridge | San Antonio, TX | Clinical Research |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| Menarini | Firenze, Italy | Small Molecules |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| , | Website down Jan 2026 - May 2026 | |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| , | Acquired by EPI, Mar 2022 | |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| ProtAffin | , | Winding Down |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Active Pass Pharmaceuticals | , | Gone |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Immagene | , | Renamed Flindr Therapeutics |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Piper Therapeutics | , | Website gone May 2020 |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Smart Biosciences | , | Renamed sb-Peptide |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| BZL Biologics | , | Gone 2003 |
| Wyeth | , | Bought by Pfizer |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| Arstasis | , | Appears Gone Sep 2017 |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| Vesper Medical | Wayne, PA | Venous Stent |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| LinaTech | Suzhou, China | Cancer treatment device |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| Lavipharm | East Windsor, NJ | Small molecules |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| , | Merged with DefiniGEN to become pixl.bio | |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| , | Renamed Novakand Pharma, Sep 2025 | |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| PL Developments | , | Parts of website taken over |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Imstem Biotechnology | , | Website gone May 2021 |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Piramal | Mumbai, India | CDMO |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Xenova | , | Acquired by Celtic Pharma |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Metris Therapeutics | , | Presumed Gone |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| Vericel | Ann Arbor, MI | Cellular Products |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Therics | , | Acquired by Integra |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Assurance Scientific Laboratories | Birmingham, AL | Molecular Technologies |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Kembiotix | , | No info, Aug 2022 |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Sprna | , | Website gone Jan 2020, no info |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| Universal Precision Instruments, Inc. | , | |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| BioSyntech | , | Bought by Piramal |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Bio-ops | , | Now SVA |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Outset Medical | San Jose, CA | Dialysis Device |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| Biocious Life Sciences | , | Now Agilent |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Akela Pharma | , | Now PharmaForm |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| JK Biopharma Solutions | , | Founder gone |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| TCG GreenChem | Ewing, NJ | |
| , | Website down May 2025 - Sep 2025 | |
| HarkerBIO | , | Shut down Apr 2019 |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| PreDxion Bio | , | Renamed Refractal |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| TeutoCell | , | Renamed Xell, 2014 |
| Oncogen | , | Acquired by BMS, 1986 |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| , | No news 2017 - Apr 2026 | |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| Kona Medical | , | Closed, Dec 2016 |
| Xhale | , | Acquired by Philips, Aug 2018 |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| NewHeart Devices | , | Gone |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Novotech | Melbourne, Australia | Clinical Research |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| , | Website down Dec 2025 - Apr 2026 | |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Guardion Health Sciences | , | Shut down |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Transnetyx | Cordova, TN | Automated PCR Services |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Velos | , | Acquired by WCG, Mar 2018 |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Amarin | Dublin, Ireland | Small Molecules |
| Ana-Gen Technologies | , | Gone post 2001 |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| CSSi | , | |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Lupin | Maharashtra, India | Generics |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| GemoPharm | , | No news 2017-2022 |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Avema Pharma | , | Bought by PL Developments |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| , | Website down Jun 2025 - Dec 2025 | |
| Altravax | , | Shut down 2016 |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Parion Sciences | Durham, NC | Mucosal Targets |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Ambion | , | Bought by Applied Biosystems 2006 |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| AblaCare | , | Renamed May Health, Sep 2022 |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| Altasciences | Overland Park, KS | Contract Research |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| Spyryx Biosciences | , | Shut down 2019 |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Bionsight | Chuncheon, Korea | Database For Research |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Sequoia Pharmaceuticals | , | Folded |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Evestra | San Antonio, TX | Women's Health |
| Institute for Drug Discovery | , | Gone |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Biohit | Helsinki, Finland | Diagnostics |
| Adrenergics | , | Gone Sep 2017 |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| Infinitopes | Oxford, UK | Vaccines |
| Elucid | Boston, MA | Arterial Analysis Software |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| BRAND | Wertheim, Germany | Liquid Handling |
| Meta-Iq | , | Website gone Jun 2020 |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| Best Vascular | , | Now Best Vascular Novoste |
| Sharp | Rhymney, UK | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Calmune | , | Liquidated |
| DFE Pharma | Goch, Germany | Excipients |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Pharmaron | Louisville, KY | R&D Services |
| Accellacare | Wilmington, NC | Clinical Research |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Macrocure | , | Merged into Leap Therapeutics |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| , | business filings late Oct 2023 - Oct 2025 | |
| Picoseq | , | Renamed Depixus |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Vivid Genomics | , | Shut down Sep 2023 |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Provecs Medical | , | Gone Nov 2019 |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Akkadix | , | Gone 2001 |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Pharmaron | Coventry, RI | API Manufacturing |
| Hesperos | Orlando, FL | Human-on-a-chip |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| MSD | Leopardstown, Ireland | Small Molecules |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| Dorphan | , | Shut down so owner could spend more time skiing |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Santen | Emeryville, CA | Ophthalmics |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Apcer Life Sciences | London, UK | Consultants |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Saniona | Glostrup, Denmark | Small Molecules |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Bastion Therapeutics | , | Shut down |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Antibiotice | Iasi, Romania | Generics |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| WntResearch | , | Shell acquired by Opsy |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| CoMind | London, UK | Non-invasive brain monitoring system |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| Novartis Animal Health | , | Acquired by Lilly |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| preclinics | Eystrup, Germany | Contract Research |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| Commence Bio | , | Gone 2018 |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| , | Acquired by ETAP Group, Oct 2023 | |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Cougar Biotechnology | , | Bought by J&J |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Senetek | , | Not sure what happened, no site, seem gone |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| , | Website down Jul 2025 - Dec 2025 | |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| CTIBIOTECH | Philadelphia, PA | Tissue Sample |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Orchestra BioMed | New Hope, PA | Medical devices |
| Bioneeds | Bangalore , India | Contract Research |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| Proteome Sciences | Surrey, UK | Proteomics |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| Predicine | Hayward, CA | Liquid Biopsy |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| , | Website under construction Dec 2024 - May 2026 | |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| CertiRx | , | Shut down |
| Ansaris | , | Gone |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Cambrian Genomics | , | Shut down Dec 2017 |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Birdotech | Shanghai, China | CDRMO |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| BioChain | Newark, CA | Sample Preparation |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| ConjuChem | , | Bankrupt 2011 |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| ViaCord | , | Part of PerkinElmer |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| Biolab | Mississauga, ON | Small Molecules |
| Synovex | , | Renamed Adheron Therapeutics |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Ileo Science | , | Seems gone Mar 2022 |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| CultureTrax | , | Shut Down Dec 2019 |
| Qardio | Covina, CA | Portable Heart Monitors |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| R/D Clinical Research | , | Website Gone |
| Elona Pharmaceuticals | , | Gone |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Targeson | , | Website gone, Mar 2017 |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| Nura Bio | South SF, CA | Small Molecule |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Siga | New York, NY | Small Molecules |
| Vivacy | Archamps, France | Aesthetic Medicine |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| GnuBIO | , | Bought by Bio-rad |
| Rinat | , | Bought by Pfizer 2006 |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| , | Acquired by Stryker, Oct 2024 | |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| TearScience | , | Acquired by J&J, Nov 2017 |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| GSK | Hamilton, MT | Vaccine additive |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| TransCellular Therapeutics | , | Gone 2019 |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Prognosys Bioscience | , | 10 years in stealth mode |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| Sage Science | Beverly, MA | DNA Fractionation |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Pneumolabs | , | Dissolved Sep 2018 |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| CareDx | Brisbane, CA | Diagnostics |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| West-Ward | , | Now part of Hikma |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| , | Shut down May 2025 | |
| Convergen LifeSciences | , | Renamed Genprex |
| Doloromics | , | Shut down Mar 2025 |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Rubicon Research | Thane , India | Generics |
| Biocodex | Gentilly, France | Microbiota Treatments |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Mendaera | San Mateo, CA | Medical Robotics |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Sancilio | , | Now Micelle BioPharma |
| AC Diagnostics | , | Website from 2004 |
| Neotech | , | Website down Jan 2019 |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation psuedo-subsidiary | |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| , | Website down Oct 2025 - Jan 2026 | |
| , | Renamed AtaiBeckley | |
| Catalyz | , | Gone |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| |
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Website down Jan 2026 - May 2026 | |
| Immune Technology Corp | New York, NY | Virology research products |
| Akubio | , | Bankrupt Sep 2007 |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Matritech | , | Assets bought by Matritech 2007 |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| , | Assets being sold off May 2026 | |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| Viva Biotech | Jiaxing , China | Contract Research |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| Halloran Consulting Group | Boston, MA | Consulting |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| Revvity | Waltham, MA | Diagnostics, Services |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Obenomics | , | No website Apr 2014 |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| Vicus Therapeutics | , | Gone 2019 |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Avance Clinical | Firle, Australia | Clinical Research |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| , | Website down Dec 2025 - Apr 2026 | |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Pharmexon | Prague, Czech Republic | Consulting |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Marical | , | Website Gone |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Elix | Tokyo, Japan | AI Drug Discovery |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| sRNA Dx | , | aka sRNAlytics |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| , | Shut down Oct 2024 | |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Promethera Biosciences | , | Renamed Callaion |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| , | Website down Nov 2025 - Apr 2026 | |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| Aadigen | , | Renamed Aanastra |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Mustang Bio | Worcester, MA | Immunotherapies |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| BioDevek | , | Formerly LabCentral, seems gone |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| , | Shut down Sep 2025 | |
| Allievex | , | Shut down Feb 2025 |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Esculon | , | Seems defunct, employees gone |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Tyrian Diagnostics | , | Gone 2012 |
| Celerion | West Conshohocken, PA | Clinical Research |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| iBridge Medical | , | Website gone Jan 2020 |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| Osteologix | , | Liquidated, Sep 2015 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| T&T Scientific | , | Website gone May 2023 |
| Piramal | Hyderabad, India | CDMO |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| , | Pivoted to defense, Feb 2026 | |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Calypte Biomedical | , | Gone |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| , | Website down Oct 2025 - Feb 2026 | |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Transmed Oncology | , | Gone? |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Valsphere | , | Website gone Nov 2019 |
| ImmuneXcite | , | Closed Oct 2017 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| Snorx | , | Renamed Zelegent, May 2015 |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Antigenics LLC | , | Now Agenus |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Ozgene | Bentley, Australia | Genetically modified mice |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| 121 Bio | , | Gone mid 2016 |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Medrobiotics | , | Bankrupt, May 2024 |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Genomas | , | Website gone May 2020 |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Getinge | Mahwah, NJ | Medical Technology |
| LifeScience PLUS | Mountain View, CA | Wound care |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| Intica Biomedical | , | Bankrupt 2014 |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Analogic | Peabody, MA | Medical Imaging |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| hC Bioscience | , | Shut down Mar 2025 |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Revance | Nashville, TN | Movement Disorder Treatment |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Cryoniss | Deeside, UK | Bio Banking |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Evogene | Rehovot, Israel | Computational Biology |
| MakroCare | San Francisco, CA | Drug Development Partner |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| iWel | Exton, PA | Glucose Meters |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| Afaxys | Charleston, SC | Women's Health |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Liposonix | , | Bought by Medicis |
| Getinge | Delft, Netherlands | Medical Technology |
| , | ||
| , | Renamed Create Medicines, Oct 2025 | |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| RegeneraTEch | , | Renamed Regencor |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Westat | Rockville, MD | Clinical trial design, management, services |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| ProteinLinks | , | Seem gone |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Trigemina | , | Shut down Aug 2020 |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Brain Vision | Morrisville, NC | EEG Systems |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| , | Renamed Grey Matters Health, Apr 2026 | |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| AllerMAbs | , | Website gone Oct 2022 |
| , | Website down Jan 2026 - Mar 2026 | |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Genexa | , | Shut down before Nov 2023 |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| R2M Pharma | South SF, CA | Drug Development Services |
| PhotoSonix Medical | , | Now a licensing outift |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| BGI | Hong Kong, China | Genetic Testing |
| |
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| DiagnoCure | , | Liquidated, Apr 2016 |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| Solvanix | , | Shut down Nov 2023 |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Trek Therapeutics | , | Shut down Sep 2019 |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| Aixlie Pharmaceuticals | , | No idea what happened |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Excelimmune | , | Closed Jul 2016 |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| US Labs | , | Bought by Labcorp |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Abnovo | , | Gone |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| SJ Pharma | , | Website gone, Nov 2018 |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Bafna | Chennai, India | Generics |
| Vericel | Cambridge, MA | Cellular Therapy |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Venebio | Glen Allen, VA | Consultants |
| Cellenion | Lyon, France | Single Cell Testing |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| Geneffects | , | Shut down Feb 2020 |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| Validation Associates | Herndon, VA | Validation Consulting |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| Splice Histology | Worcester, MA | Histopathology Services |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Celerion | Lincoln, NE | Clinical Research |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| , | Renamed Ladder Bio, Nov 2025 | |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Revolution Biomanufacturing | Canton, MA | mRNA, lipid nanoparticle CDMO |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| GliaGen | , | Renamed CaCy Therapeutics |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Nanogen | , | Now Epoch Biosciences |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| , | Website down Oct 2025 - Feb 2026 | |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Procognia | , | Website Gone, Layoffs 2014 |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| Ascend Genomics | , | Shut down |
| Carrington Labs | , | Changed Name to DelSite |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| Gataca | , | Gone |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website down Aug 2025 - Jan 2026 | |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| CereScan Corp | , | Renamed CereHealth |
| Kura Oncology | San Diego, CA | Small Molecules |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| , | Website down Nov 2025 - Dec 2025 | |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| NeuroWave Systems | Beachwood, OH | EEG |
| AlphaVax | , | No employees on LI. Not sure active |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Acuvax | , | Pivoted to investments, 2014 |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Putney | , | Acquired by Dechra, Mar 2016 |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Chrysalis | Morrisville, NC | GMP Space |
| , | Acquired by Merck, May 2026, $6.67B | |
| Percivia | , | Shut Down 2012 |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| ProPharma Group | Deerfield, IL | Consulting |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Santen | Nara, Japan | Ophthalmics |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cydan Development | , | Shut down Sep 2021 |
| OrthoData | , | Renamed Intellirod Spine |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| , | Website down Jul 2025 - Dec 2025 | |
| Groton Biosystems | , | Gone before Jun 2015 |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| NuLife Sciences | , | Shell acquired for a security business |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Norgine | Hengoed, UK | Specialty Pharma |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| MSD | Dublin, Ireland | Women's Health Products |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Curl Bio | , | Shut down Feb 2020 |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Medrobotics | , | Bankrupt Jun 2022 |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| Sanarus | , | Acquired by Hologic, 2020 |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Dipharma | Baranzate, Italy | APIs, Generics |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| XtalPi | Beijing, China | AI Drug Design |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Avail Medsystems | , | Tech sold Mar 2024 |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Boston Scientific | Valencia, CA | Medical Devices |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Koelis | Meylan, France | Prostate Biopsy System |
| Ergomed | Raleigh, NC | Clinical Research |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Norgine | Madrid, Spain | Specialty Pharma |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| Karo Bio | , | Renamed Karo Pharma |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| CSL Behring | Bradley, IL | Biologics |
| Hemanext | Avon, MA | Transfusion Technologies |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| AzurRx | , | Merged into First Wave Bio |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| MURO PHARM | , | Dissolved, May 2007 |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| IQVIA | Durham, NC | Clinical Research |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| Basecamp Research | London, UK | AI-Biology Data |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| MyoSyntax | , | Gone 2021 |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| , | Website down Jul 2025 - Dec 2025 | |
| , | Liquidated Jun 2025 | |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Medtronic | Cincinnati, OH | Medical Devices |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Novotech | Hong Kong, China | Clinical Research |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Verasonics | Kirkland, WA | Research Ultrasound |
| Cell Therapy Ltd | , | Renamed Celixir |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| SR Pharma | , | Now Silence Therapeutics |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Advaned Viral Research | , | Shut down 2009 |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Pangenetics | , | Bought by Abbott |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| Eccogene | Shanghai, China | Small Molecules |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| DanPET | , | One guy, Feb 2024 |
| AB Science | Paris, France | Small Molecules |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| , | Shut down Jan 2025 | |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| Neurogene | New York, NY | Genetic Therapies |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| LyoTechnica | , | Gone |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Parsolex | , | |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| Tisucor | , | Shut down Feb 2020 |
| Nanobiotix | Paris, France | Nanoparticles |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| , | Renamed Valion Bio, Apr 2026 | |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| Amoytop Biotech | Xiamen, China | Biologics |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Elanex Pharmaceuticals | , | Gone |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| August Therapeutics | , | Shut down Dec 2024 |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Virometix | Schlieren, Switzerland | Vaccines |
| , | Inactive May 2025 | |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| GenEscence | , | Gone Jul 2013 |
| Gene Signal | , | Bankrupt, Apr 2021 |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Cairn Research | Kent, UK | Scientific Instruments |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| Flownamics | Madison, WI | Automated Sampling |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| XtalPi | Cambridge, MA | AI Drug Design |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Recon Therapeutics | , | Shut down Jun 2017 |
| RxGen | , | Renamed Virscio, Jan 2020 |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Veeva Systems | Toronto, ON | Life Science Software |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Northern Lipids | , | Renamed Transferra |
| , | Merged with Cohance, May 2025 | |
| In Cell Art | , | Website taken over Feb 2025 |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| NemaPharm | , | Defunct? |
| GenSure | Shijiazhuang, China | Diagnostics |
| Greppo Technologies | , | Renamed Verix Health |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| , | No news 2020 - Dec 2025 | |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| Modular Medical | San Diego, CA | Insulin Pump |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Stasys Medical | , | Shut down Feb 2025 |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| , | Shut down Jan 2026 | |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| CoAxia | , | Closed down Spring 2013 |
| Trilations | New York, NY | Strategic Consulting |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Abpro | Lexington, MA | Antibodies |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| NeuroTherapeutics | , | Gone |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Dendritix | , | Renamed Argos Therapeutics |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Provasculon | , | Website Gone, Apr 2014 |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| Cognis Corp | , | Acquired by BASF 2010 |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| Alltrna | Cambridge, MA | tRNA therapies |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| Whole Biome | , | Renamed Pendulum Biosciences |
| Bach Pharma | , | Shut down late 2023 |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Allux Medical | , | Shut down, Feb 2009 |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Abnovel | , | Gone Jul 2010 |
| InteKrin | , | Owned by Coherus Biosciences |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| , | Acquired by Certara, Oct 2024 | |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| Tides Medical | Lafayette, LA | Biologics |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| Curadev | Kent, UK | Immuno-oncology |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Velquest | , | Bought by Accelrys Jan 2012 |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| JustRight Surgical | , | Renamed Bolder Surgical |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| Anumana | Cambridge, MA | AI ECG reading |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Acretia | , | Gone |
| MSD | Brinny, Ireland | Small Molecules |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| BrainScope | Bethesda, MD | EEG characterization |
| Medical Device Usability | , | Acquired by UL, 2018 |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| Molecular Loop | Woburn, MA | NGS Technology |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Gensco Pharma | Doral, FL | Transdermals |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Symbollon | , | Gone |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| , | Renamed Solario Bio | |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Defyrus | , | Website gone Nov 2017 |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Neugenesis | , | Bought by Intrexon, 2011 |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Analog Pharma | Princeton, NJ | Generics |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| Vaccibody | , | Renamed Nykode Therapeutics |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| IMS Health | , | Merged with Quintiles, May 2016 |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Hubot CDMO | South Bend, IN | Contract Filling |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| AdipoGenix | , | Gone Jun 2012 |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Topivert | , | Liquidating Jan 2021 |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| PreciThera | , | Website taken over, Dec 2021 |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Aranscia | Houston, TX | Diagnostic Software |
| CardioCanary | , | Founders gone. Doubt it's active |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| OncoQr | , | No news 2017 - Oct 2024 |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| , | Gone Jan 2026 | |
| AsymBio | Jinshan, China | Biologics CDMO |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| preclinics | Potsdam, Germany | Contract Research |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Tensys Medical | , | Website gone Sep 2017 |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| Organon (2) | Jersey City, NJ | Women's Health |
| , | Website down Dec 2025 - Jun 2026 | |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| , | Acquired by Syner-G BioPharma Group | |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| , | Website down May 2025 - Oct 2025 | |
| Groove Biopharma | , | Gone 2015 |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| , | ||
| Alfama | , | Merged into Proterris, May 2017 |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| JABio | , | Shut Down May 2021 |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Redpoint Research | , | Gone 2019 |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Genex Pharma | Mumbai , India | Generics |
| Roche | Penzberg, Germany | Diagnostics |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Ennov | Paris, France | Software Solutions |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| , | No news 2015 - Jan 2026 | |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| Advancells | Noida, India | Stem Cell Treatments |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Biowarn | , | Gone |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Senzime | Uppsala, Sweden | Devices |
| XtalPi | Shanghai, China | AI Drug Design |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| Amstem | , | SEC problems |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| IDRx | , | Acquired by GSK, Feb 2025 |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| MMI Genomics | , | Assets bought by Neogen |
| , | Shut down 2025 | |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| , | Subsumed into Synoptics | |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| TruGenomix | , | Renamed Polaris Genomics |
| Blackfynn | , | Gone Apr 2022 |
| mAbRx | , | Gone |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Applied Therapeutics | New York, NY | Small Molecules |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| Cytiva | Marlborough, MA | Medical Devices |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Ergomed | Krakow, Poland | Clinical Research |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Delpharm | Reims, France | Contract Manufacturing |
| Oxehealth | , | Pivoted to mental health platform |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| CNS Research | , | Seem gone, 2020 |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Cell Genesys | , | Merged with BioSante |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Velcura Therapeutics | , | Website Gone |
| Genmab | Plainsboro, NJ | Biologics |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| ParinGenix | , | Gone, 2012? |
| Microphage | , | Bankrupt Jun 2013 |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Enci Therapeutics | , | No website, business suspended by NC |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| , | Website down Dec 2025 - Jun 2026 | |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| Apobiologix | Toronto, ON | Biosimilars |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| QInstruments | Jena, Germany | Lab Instruments |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Bioventus | Cordova, TN | Orthobiologics |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| Apofore | , | Shut down, Dec 2015 |
| IMMY | Norman, OK | Fungal Diagnostics |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| amcure | , | Liquidated Sep 2024 |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| Ipca Laboratories | Mumbai, India | APIs |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| Altos Therapeutics | , | Gone Jun 2019 |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Stryker | Mahwah, NJ | Medical Devices |
| Reserva | , | Renamed NeurMedix, 2016 |
| , | Website down Oct 2025 - Jan 2026 | |
| Audubon Bioscience | Houston, TX | Biospecimens |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| TheraCoat | , | Renamed UroGen Pharma |
| Excaliard | , | Bought by Pfizer 2011 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Telo Genomics | Toronto, ON | Diagnostics |
| Cue Biopharma | Boston, MA | Immunotherapy |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Formation Biologics | , | Rebranded as Forbius |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| AniLocus | Germantown, MD | Preclinical CRO |
| General Oncology | Brookline, MA | Cancer Therapies |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Correlogic | , | Assets bought by Vermillion 2011 |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Medtronic | Memphis, TN | Medical Devices |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| Moximed | Fremont, CA | Joint treatment |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Stryker | Salt Lake City, UT | Medical Devices |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Quintessence Biotech | , | Biomimetic Separation |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| , | Liquidating, Sep 2025 | |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Divide and Conquer | , | Website gone Mar 2024 |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| Lupin | Goa, India | Generics |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| Bionode | , | Shut down Mar 2024 |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| NextGen Sciences | , | Defaulted, sued by employees |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| , | Website down Nov 2025 - Mar 2026 | |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Able Labs | , | big FDA trouble, gone |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| PathAI | Boston, MA | AI Powered Pathology |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| GenEndeavor | Hayward, CA | Diagnostics |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| Accellacare | Knoxville, TN | Clinical Research |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| Aixa Bio | Cambridge, MA | AI genomics |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| PluriCell | , | Renamed LizarBio |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| miR Scientific | , | Renamed miRNA Scientific |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| , | Website down Oct 2025 - Feb 2026 | |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| UniteLabs | , | Shut Down |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Bio Processing | , | Bought by Bio-rad |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| Diagast | Loos, France | Transfusion Reagents |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Minakem | Dunkerque , France | API Manufacturing |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| CanCure | , | No news 2017 - 2024 |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| ARCBio | , | Shut down 2014 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| , | Website down Aug 2025 - Jan 2026 | |
| Teva | West Chester, PA | Small Molecules |
| ResearchDx | Irvine, CA | Diagnostics |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| , | Acquired by IQVIA | |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| Pevion Biotech | , | Gone, 2-19-14 |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| AccuVein | Medford, NY | Vein Visualization |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| , | Acquired by Paradigm Health, Jan 2023 | |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| LabConnect | Johnson City, TN | Lab Services |
| Keenova | Hazelwood, MO | Small Molecules |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| Stago | Marseille, France | Diagnostics |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| , | Website down Oct 2025 - Jan 2026 | |
| CMD Bioscience | , | Closed, 2015 |
| , | Website down Oct 2025 - Feb 2026 | |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Cytel | Pune, India | Clinical software, statistical services |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| La Jolla Biologics | , | Website gone Nov 2014 |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Quantamerix | , | No info since 2012, never registered in MA |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Alerchek | , | Closed late 2016 |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| , | Website down Jul 2025 - Jan 2026 | |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| AxoTect | , | Phantom company |
| Alverix | , | Acquired by BD, Jan 2014 |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| NKT Therapeutics | , | Shut down May 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Cala Health | San Mateo, CA | Neurological Device |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| , | Renamed Hermes Biosciences | |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| Ventaleon | , | Shut down 2020 |
| Clinilabs | Eatontown, NJ | Clinical Research |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Coral Drugs | New Delhi, India | APIs |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Kailo Pharma | , | |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| Catawba Research | Charlotte, NC | Clinical Research |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| NeurOptics | Irvine, CA | Pupillometry |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| EndoLogic | , | Seems inactive, Aug 2023 |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| Sicor Biotech | , | Bought by Teva 2004 |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Manhattan Pharmaceuticals | , | Gone |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| United Neuroscience | , | Renamed Vaxxinity |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Cytosolix | , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| nitec Pharma | , | Merged with Horizon Pharma |
| BioClinical Solutions | Chicago, IL | Clinical Trial Solutions |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Soin Neuroscience | , | Seems like one guy |
| Odyssey Thera | , | Shut down 2014 |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Clear Image Technology | , | Now CIT Ortho |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| Noeledge | , | Shut down Jul 2024 |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| , | Acquired by StarFish Medical, Nov 2024 | |
| Zylacta | , | No news 2015 - Oct 2024 |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| , | Seems renamed to Lusis Biosciences | |
| CeQur | Luzern, Switzerland | Insulin pump |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| Dornier MedTech | Sillingy, France | Urology Devices |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Ciphergen | , | Now Vermillion |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| , | Shut down Jan 2025 | |
| Mindflow Design | , | Now part of MPE |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Automata | London, UK | Lab workflow automation platform |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| argenx | Boston, MA | Antibody therapies |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| StaphOff Biotech | , | Shut down 2017 |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Attogene | Austin, TX | Rapid Diagnostics |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| SARcode | , | Bought by Shire Mar 2013 |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Ergomed | Mumbai, India | Clinical Research |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| , | Acquired by Scantox, Sep 2024 | |
| Medispect | , | Shut Down 2013 |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| Trident Lifeline | Surat, India | Generics |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| Oticon | Smørum, Denmark | Hearing Aids |
| Scinomix | Earth City, MO | Lab Automation Products |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Precision Research Institute | , | Shut down Apr 2024 |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| , | Founder, Principal gone Sep 2024 | |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Iomai | , | Bought by Intercell 2008 |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| , | Website down May 2025 - Dec 2025 | |
| Central Pharma | Bedford, UK | Filling, Packaging |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| Clearbridge Biomedics | , | Renamed Biolidics |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| , | No news 2018 - May 2026 | |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| BBOT | South SF, CA | RAS-targeted small molecules |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| APSciences | , | Website gone Aug 2022 |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Zuma Biosciences | , | Company Gone |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Getinge | Ankara, Turkey | Medical Technology |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Cue Health | , | Shut down May 2024 |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| InnoCare | Nanjing, China | Cancer Treatments |
| Santen | Tampere, Finland | Ophthalmics |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Inspirata | Tampa, FL | Cancer Insights |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| Bakhu Pharma | , | Bankrupt, location sold |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Nura | , | Acquired by Omeros |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| iCeutica | , | Seems gone, Jan 2022 |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| Daktari Diagnostics | , | Gone 2017 |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| Signatur Biosciences | London, UK | PCR Platform |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| BIND Biosciences | , | Now BIND Therapeutics |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Getinge | La Ciotat, France | Medical Technology |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| PluriSelect | El Cajon, CA | Cell Separation |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| DyNAbind | , | Shut down Apr 2025 |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| AtCor Medical | , | Now part of CardieX |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Medipacs | , | Shut down Jul 2024 |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| PolyTherics | , | Joined Antitope to become Abzena |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Envision Pharma | , | Merged with UBC |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| , | Acquired by Bruker, Sep 2020 | |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Nabla Bio | Cambridge, MA | Antibody Design |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| , | Acquired by Immedica, Feb 2025 | |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Hua Medicine | Shanghai, China | Small Molecules |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Axikin Pharmaceuticals | , | Closed per Google |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Microsize | Quakertown, PA | Microionization CDMO |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| Antitope | , | Now part of Abzena |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| VG Life Sciences | , | Shell company |
| , | Winding down Apr 2026 | |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| AstraZeneca | Boston, MA | Biologics |
| Novonesis | Beijing, China | Enzymes |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Inventiva | Daix, France | Small Molecules |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| Cordis | Miami Lakes, FL | Medical Devices |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Ipsen | Wrexham, UK | Biologics |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| , | Renamed LeonaBio, Jan 2026 | |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Affinity Bio | , | Renamed MyriO Tx |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Gene Labs | , | Bought by GSk 2008 |
| Metenova | ZZ, Sweden | Mixers |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| DM Clinical Research | Houston, TX | Clinical Research |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| , | Website down Aug 2025 - Jan 2026 | |
| DynoSense | , | Shut down Sep 2022 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Texcell | Shanghai, China | Contract Research |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Starpharma | Abbotsford, Australia | Antibacterial |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| CBH ClinTrials | , | now CenExelCBH |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| Smithers | Akron, OH | Contract Research |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Trudell Medical | London, ON | Inhalation Devices |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| DesignMedix | , | Shut down Aug 2020 |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| Alexis Biotech | , | Dissolved May 2015 |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Laureate Pharma | , | Acquired by Gallus |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Corza Medical | Shanghai, China | Surgical Devices |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| NTRC | , | Now Oncolines |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| ImmuVen | , | Website gone, Dec 2015 |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Penwest | , | Bought by Endo |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| , | Website down Aug 2025 - Jan 2026 | |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| BridGE Genomics | , | Gone 2022 |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| SteriTech | Sligo, Ireland | Process Equipment |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Crown Bioscience | San Diego, CA | Drug Development |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| , | Website taken over, Jan 2026 | |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| bioRASI | Aventura, FL | Clinical Research |
| Helsinn | Dublin, Ireland | Small Molecules |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| Eternans | , | Shut down Jul 2022 |
| Perlara PBC | , | Shut down Feb 2019 |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Genialis | Boston, MA | Bioinformatics |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| iBio | San Diego, CA | Antibody Therapies |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| Amachumu Bio | , | Shut down April 2021 |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Ionian Technologies | , | Gone Mar 2016 |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| EuroAPI | Paris, France | API Production, CDMO |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Predictive Biosciences | , | Closed 2013 |
| Rhombus Pharma | Gandhinagar, India | Generics |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Kastle Therapeutics | , | Closed May 2018 |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| Altasciences | Everett, WA | Contract Research |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Adaptix | Oxford, UK | Medical imaging |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| GenoSpace | Boston, MA | Platform for genomic data |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| PRA International | , | Now PRA Health Sciences |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Personalis | Fremont, CA | Genome Services |
| CureGene | Shanghai, China | |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| Cibiem | , | Shut down May 2021 |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| , | Website down Oct 2025 - Feb 2026 | |
| Stryker | Flower Mound, TX | Medical Devices |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Newormics | , | Renamed vivoVerse, late 2022 |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Lombard Medical | Didcot, UK | Medical Devices |
| LexaMed | Toledo, OH | Life Science Consulting |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| MeiRui Pharma | , | Bought by GSK |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| , | Acquired by Lantheus, Jan 2025 | |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Almac | Craigavon, UK | Pharmaceutical Services |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| Calcionics | , | Shut down 2010 |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Roowin | Riom, France | Chemical Synthesis |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Proveri | , | Gone 2016 |
| Qbiogene | , | No website. Fisher sells their products |
| Peptone | London, UK | Translational Biophysics |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| , | Website down Sep 2025 - Dec 2025 | |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| , | Website down May 2025 - Dec 2025 | |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| AbbVie | Dublin, Ireland | Medical Devices |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| CONMED | Largo, FL | Surgical, Medical Devices |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| NeuroPharm | , | Liquidated 2010 |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| GeneEx | , | Now RevDia |
| Sharp | Heerenveen, Netherlands | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Graybug | , | Now Graybug Vision |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| FusionBio | , | Website down Sep 2025 |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Linical | Stuart, FL | Clinical Research |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Veravas | Oakdale, MN | Diagnostics |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| , | Acquired by Epitype, Oct 2025 | |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| Parexel | Newton, MA | Clinical Research |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| PreventAGE Health Care | , | fka Journey Biosciences |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| Nigra | , | Acquired by Vernalis |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Idience | San Francisco, CA | Cancer Therapies |
| Tolerx | , | Shut Down 2011 |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Precision Virologics | , | Precision Virologics |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| BG medicine | , | Gone 2019 |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Simondr | , | Website gone, President has new job |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Bioptimus | Paris, France | AI Drug Discovery |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| BioVascular | , | 2007 website as of Mar 2019 |
| Minimally Invasive Devices | , | Shut down |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| , | Website taken over Feb 2026 | |
| Niche Generics | Hitchin, UK | Contract Generics |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| Circadiance | Export, PA | CPAP Mask |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| NeoVista | , | Gone 2011 |
| Imalux | , | Ceased Operations, Apr 2014 |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| Bioquanta | , | Gone 2013 |
| , | Acquired by Lonza, Apr 2017 | |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| NuVascular Technologies | , | Shut down Nov 2021 |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| ArunA Biomedical | , | |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Metrad Biosystems | , | Website gone |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Hemaquest | , | Gone by 2017, No info |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| , | Website down Oct 2025 - Feb 2026 | |
| Humanyx | , | No website, Seems gone |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| BioCydex | , | No info 2019 - Mar 2025 |
| Vascular Technology | Nashua, NH | Surgical Devices |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| Archimedic | West Chester, PA | Medical Device Consulting |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Sharp | Conshohocken, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Almac | Souderton, PA | Pharmaceutical Services |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| Embecta | Parsippany, NJ | Diabetes Care |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Epigene Labs | Paris, France | Data Integration Platform |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| LifeQual Pharmaceuticals | , | Website Gone |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Sunho Biologics | Nanjing, China | Biologics |
| MWG Biotech | , | Owned by Eurofins |
| , | Acquired by MMS, Feb 2025 | |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Ocean Therapeutics | , | Shut down June 2013 |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| Light Sciences Oncology | , | Shut down late 2020 |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Chanelle Pharma | Amman, Jordan | Generics |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Amaranth Medical | , | Website gone, Apr 2019 |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Medtronic | Shoreview, MN | Medical Devices |
| Biokit | , | Rolled into Werfen |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Eurosequence | , | Website gone Jan 2020 |
| NovaLead Pharma | Pune, India | Small Molecules |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Tanai Therapeutics | , | Obesity Treatment |
| Ottobock | Königsee, Germany | Prosthetics |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| LFB | Paris, France | Plasma derived drug products |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| Accium BioSciences | , | Shut down Oct 2024 |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Recipharm | Strangnas, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Tarsa Therapeutics | , | Product rights acquired |
| Angiosonics | , | Shut down 2002 |
| , | No news 2020 - Apr 2026 | |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Theramex | London, UK | Women's Health |
| Gerostate Alpha | , | Shut down Dec 2024 |
| BioFluentLabs | , | Shut down July 2012 |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| APIE Therapeutics | , | Gone Jun 2025 |
| Theracos | , | Renamed TheracosBio |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| MIFCOR | , | Founders both gone Feb 2021 |
| Folia Biotech | , | Website Gone May 2018 |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| accuFD | , | Closed Dec 2017 |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| FineHeart | Pessac, France | Heart Failure Device |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| Mederi Therapeutics | , | Now Mederi-RF |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| Aikium | Berkeley, CA | AI Drug Discovery |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Novotech | Taipei, Taiwan | Clinical Research |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| SomaLogic | Boulder, CO | Blood Analysis |
| DiObex | , | Shut Down 2009 |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| SteriTech | Surrey, UK | Process Equipment |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Niramai | London, UK | AI-breast cancer detection device |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Biomendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Covenant Therapeutics | , | Gone |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| GL Technologies | San Diego, CA | Calibration Services |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Tapestry Pharmaceuticals | , | Gone |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| TTP Labtech | , | Renamed SPT Labtech |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Medtronic | Jacksonville, FL | Medical Devices |
| PharmaVigilant | , | Gone 2014 |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Cytovale | South SF, CA | Sepsis Detection |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Mabqi | Grabels, France | Antibody Discovery |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| RS Medical | Vancouver, WA | Medical Devices |
| Zivena | , | Gone |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Amplifold | , | DNA origami nanotechnology |
| American Biooptics | , | Renamed Avivo BioOptics |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| CellXplore | , | Gone |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| Bioserve | , | Acquired by ReproCell, 2014 |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Proxima | New York, NY | AI Protein Folding Platform |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| NinePoint Medical | , | Seems gone Sep 2020 |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| , | Winding down Jan 2026 | |
| , | Website taken over, Jan 2026 | |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| Vernacare | Newtown, UK | Surgical Devices |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| , | Website down Dec 2025 - Apr 2026 | |
| Quanticate | Bangalore, India | Clinical Research |
| Gennova Bio | Pune, India | mRNA vaccine |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| , | Website down Sep 2025 - Feb 2026 | |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Altasciences | Auxvasse, MO | Contract Research |
| |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| , | Acquired by eurifins, Sep 2024 | |
| Elite Research Institute | , | Gone, May 2018 |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Pfizer | Puurs, Belgium | Packaging |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| EsbaTech | , | Bought by Alcan |
| Eos Biosciences | , | Shut down Oct 2020 |
| PregLem | , | Acquired by Richter, Oct 2010 |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| Kegelbell | , | Shut down, Dec 2024 |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| Avenge Bio | , | Shut Down Jul 2024 |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| BioVolutions | , | Gone |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| ARC Medical | , | Acquired by Typenex Medical |
| Arete Therapeutics | , | Out of Business |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| Lab Owl | , | Part of Inflexion Point |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Celsense | , | Shut down Dec 2021 |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| , | Website down Jul 2025 - Dec 2025 | |
| Trophea Development | , | Liquidated Dec 2019 |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Avexxin | , | Rebranded as Coegin Pharma |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| MicroPort | Clamart, France | Medical Devices |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Accellacare | Winston-Salem, NC | Clinical Research |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| , | Website down Jan 2026 - May 2026 | |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| VasoRx | San Diego, CA | RNA delivery |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| Altheos | , | Closed |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Altasciences | Cypress, CA | Contract Research |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Cognosetta | , | Gone 2021 |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| , | Website down Feb 2025 - Dec 2025 | |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| Delpharm | Huningue, France | Contract Manufacturing |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| CytRx | , | Renamed LadRx Sep 2022 |
| QT Ultrasound | , | Renamed QT Imaging |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| AdrenaCard | , | Gone 2019 |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Northway Biotech | Waltham, MA | Contract research |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| IR2Dx | , | Gone, 2019 |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| Integer | Alden, NY | Medical & Surgical Devices |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Lusaris Therapeutics | , | Shut down May 2023 |
| 14M Genomics | , | Shut down, Feb 2016 |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Jenken Biosciences | , | Shut down by 2014 |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Nteryx | , | Changed name to Ardelyx |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Abbott | Alameda, CA | Diabetes Care |
| Catalina Pharma | , | No info 2017-2022 |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Stromedix | , | Bought by Biogen Idec 2012 |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Dey LP | , | Bought by Mylan 2007 |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| Predictive Therapeutics | , | Renamed NeoTX |
| , | Acquired by Novacyt Group | |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| SenzaGen | Lund, Sweden | Genomic Assays |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| , | Website down Jan 2026 - Apr 2026 | |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cellenion | Berlin, Germany | Single Cell Testing |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| SRI International | Menlo Park, CA | Independent Research |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| , | Acquired by Sensei Biotherapeutics, Feb 2026 | |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| Inverness Medical | , | Renamed Alere 2011 |
| Onodera | Kanagawa, Japan | Gene Therapy |
| 3D Biomatrix | , | Closed down |
| Myoposity Therapeutics | , | Gone |
| , | Acquired by Instem, Jul 2025 | |
| Coordination Therapeutics | , | Not Active |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Blansett Pharmacal | , | Gone Jan 2019 |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Sixal | , | SBIR, Presumed defunct |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Grunenthal | Origgio, Italy | Small molecules |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Solexa | , | Merged with Illumina 2006 |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Biosion | Nanjing, China | Bispecific Antibody |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| , | Website down Sep 2025 - Dec 2025 | |
| Applied Molecular Genetics | , | Renamed Amgen |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| Aztech Sciences | , | Website gone Jun 2021 |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| DDi | Singapore, Singapore | Clinical Software |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Alibion | , | Website down May 2021 - Sep 2021 |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| VLST Corp | , | Wound Down, Jun 2013 |
| Kelliop | Newark, CA | Diagnostic Reader |
| Proscia | , | |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Synlab | Munich, Germany | Clinical Lab Services |
| Xegen | Gemenos, France | NGS Data Analysis |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| Davol | , | Acquired by Bard, 1980 |
| HpVac | , | Renamed Atopia Therapeutics |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Acologix | , | Closed Aug 2011 |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| Evidera | , | Acquired by PPD, 2016 |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| EndoInSight | , | Website taken over Sep 2021 |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| , | Website down Jun 2025 - Dec 2025 | |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| Sonexa Therapeutics | , | Closed 2013 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Roche | Mississauga, ON | Small Molecules |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| NsGene | , | Website gone |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Metabolex | , | Now CymaBay Therapeutics |
| Oticon | Somerset, NJ | Hearing Aids |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| , | Shut down June 2024 | |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| Agrisera | Vännäs, Sweden | Antibodies |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| , | Shut down Jan 2024 | |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| , | Website down Apr 2026, seems bankrupt | |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| Aracea Therapeutics | , | No website Aug 2022 |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| Suir Pharma | , | Bankrupt, May 2016 |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Delpharm | Tours , France | Contract Manufacturing |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| Synlogic | , | Shut down Sep 2024 |
| AndroScience | , | Ancient website, no news 2014-2023 |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| Baxter | Grosotto, Italy | Medication Delivery |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Selventa | , | Closed 2016 |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| ProCrysta Biologix | , | Shut down 2018 |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Devsynthesis | Austin, TX | Chemistry CRO |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| Actis Biologics | , | Gone |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Gilead | Oceanside, CA | Small Molecules |
| , | Website down Dec 2025 - Apr 2026 | |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| Pharmaron | Beijing, China | R&D Services |
| Voitheia Bioscience | , | |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| DNAtrix | , | Gone late 2023 |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Xenikos | , | Shut down early 2023 |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Tal Medical | , | Gone |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| MetaStat | , | Website gone May 2019; Shell Company |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| , | Website down Sep 2025 - Dec 2025 | |
| Anoixis | Natick, MA | Pharmacometric Services |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Atherotech | , | Shut down Feb 2016 |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Celerion | Zurich, Switzerland | Clinical Research |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Stimwave | , | Bankrupt, Oct 2022 |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Indero | Montréal, QC | Dermatology Clinical Research |
| , | Shut down Oct 2024 | |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| Valor Biotechnology | , | Renamed Roivant |
| Neoantigenics | , | Website gone Sep 2017 |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Meditrial | New York, NY | Clinical Services, Software |
| Sierra Surgical | , | Shut down Feb 2019 |
| Obecure | , | Inactive, no info |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Sanofi | Midrand, South Africa | Biologics |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| ImmBio | , | Shut down Nov 2019 |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Roche | Basel, Switzerland | Diagnostics |
| Menarini | L'Aquila, Italy | Small Molecules |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| MabSpace Biosciences | , | Renamed Transcenta |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Oncofactor | , | Gone 2016 |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| Epocal | , | Acquired by Alere, Feb 2013 |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Abiologics | Cambridge, MA | Synteins |
| Evozyne | Chicago, IL | Protein Design Platform |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| , | Website down Dec 2025 - Apr 2026 | |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| VAXX | , | Not sure what happened to them |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Averion | , | Now Aptiv |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| RxCelerate | Cambridge, UK | Contract Services |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| XenaCare | , | Gone |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| GigaGen | San Carlos, CA | Immune therapeutics |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| Bionsight | Seoul, Korea | Database For Research |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| Celregen | Hangzhou, China | iPSC |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Axya medical | , | Gone 2012 |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| Zai Lab | Hong Kong, China | Small Molecules |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| , | Acquired by Aptean, Oct 2016 | |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| CardiRen Biomedical | , | Gone Aug 2017 |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| Targenics | , | No website Mar 2020 |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Sania Therapeutics | London, UK | CNS Treatments |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| Biological Dynamics | , | Shut down Jul 2024 |
| Abbott | Donegal, Ireland | Diagnostics |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| Harmony Labs | , | Now Ei |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Generex Biotechnology | , | Website gone Feb 2024 |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| EXO Biologics | Liège, Belgium | Exosomes |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| Epic Sciences | , | Shut down May 2025 |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| , | Website down Dec 2025 - Apr 2026 | |
| Reach Separations | Nottingham, UK | Purification Services |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Amrita Therapeutics | , | Seems gone |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Medtronic | Galway, Ireland | Medical Devices |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| 3B BlackBio | Bhopal, India | PCR products |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Getinge | Hechingen, Germany | Medical Technology |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Curadigm | , | folded into Nanobiotix |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Centocor | , | Renamed Janssen Biotech |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| InVasc Therapeutics | , | Shut down 2012 |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Biomax Informatics | , | Acquired by Labvantage |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| Micropore Technologies | Hyderabad, India | Membrane-Based Process Equipment |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Stago | Gennevilliers, France | Diagnostics |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Nephros | South Orange, NJ | Dialysis Devices |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Iontas | , | |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Nanobac Pharmaceuticals | , | Gone |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Annova Chem | , | Gone, 2017 |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| NovoMedix | San Diego, CA | Small molecules |
| JAJ International | , | Website not working, redirecting strangely |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| genOway | Lyon, France | Rat and cell models |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Getinge | Suzhou, China | Medical Technology |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| Syneos Health | Princeton, NJ | Clinical Development |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Abbott | Sylmar, CA | Device Manufacturing |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| Protelica | , | Dissolved, Dec 2006 |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Novartis | Emeryville, CA | Diagnostics |
| CEL-SCI | Vienna, VA | Biologics |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| MicroCam | , | Shut down 2015? |
| , | Website down Nov 2025 - Apr 2026 | |
| Medica | , | Gone before 2019 |
| Formulatrix | Bedford, MA | Lab Automation |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| Tryton Medical | , | Shut down Jan 2021 |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| 89bio | San Francisco, CA | Liver Treatments |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| , | Shut down Sep 2025; fka GenoFAB | |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| T-Ray Science | , | Renamed Verisante |
| Serentis | , | Website Gone |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| ClinArt | , | Now ClinArt MENA |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Resilience | East Norriton, PA | Biomanufacturing |
| Maccine | , | Gone |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| NeuroTransit | , | Behind on taxes in CA |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Catalent | Winchester, KY | Contract Manufacturing |
| Biotagenics | , | Renamed MedBiome |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| GlySens | , | Bankrupt Nov 2022 |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Plureon | , | Website gone, one employee after 17 years |
| Extract Technology | Mauston, WI | Containment Equipment |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Trillium Diagnostics | , | Closed Jul 2016 |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| , | ||
| Cetero Research | , | Renamed PRACS Institute |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Squarex | , | Gone as of Oct 2021 |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Intellikine | , | Bought by Millennium 2011 |
| Pace | San German, PR | Analytical Testing, CDMO |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| CoreBiome | , | Merged into Diversigen |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| , | Website down Oct 2025 - Feb 2026 | |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| Keenova | Dublin, Ireland | Small Molecules |
| Alcon | Zug, Switzerland | Eye-Care Products |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Santen | Osaka, Japan | Ophthalmics |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| Verix Health | , | Renamed Serpex Medical |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Getinge | Antalya, Turkey | Medical Technology |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| GeNO | , | Renamed Vero Biotech, 2018 |
| SEQENS | Ecully, France | APIs, Ingredients |
| Michigan Clinical Research Institute | , | |
| iCareDx | , | Renamed AcuamarkDx |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| Iquity Labs | , | Merged into Decode Health |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Nexgenia | , | Gone Dec 2019 |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| Purely Proteins | , | All employees gone, no info |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| , | 16 years in, CMO is CEO elsewhere Dec 2025; fka Glycoregimmune | |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| D-Pharm | , | Website Gone, Aug 2016 |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| , | Website down Jul 2025 - Jan 2026 | |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| , | Acquired by Avania, Oct 2024 | |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| IQVIA | Lenexa, KS | Clinical Research |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| Knopp Biosciences | , | |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| STX-Med | , | Renamed Cefaly |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Sirana Pharma | , | Merged with Apexis Bio |
| GeneProt | , | Shut down Apr 2005 |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| , | Website down Jul 2025 - Dec 2025 | |
| Cearna Aesthetics | , | Product acquired by Allergan |
| One Drop | , | Gone Dec 2024 |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Immunovaccine | , | Rebranded IMV, 2018 |
| BGI | Copenhagen, Denmark | Diagnostics |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Zetra Biologicals | , | Gone |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| Osteolab | , | Spam site |
| Integer | Chaska, MN | Medical & Surgical Devices |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| , | Pivoted to crypto, Apr 2026 | |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| NovoKera | , | Merged into Longevity Biomedical |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Menarini | Dresden, Germany | Small Molecules |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| Ortho Development | Draper, UT | Ortho Implants |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| , | Website gone Feb 2026 - Jun 2026 | |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Sepracor | , | Now Sunovion |
| Invenra | Madison, WI | Antibodies and their derivatives |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Anavex Life Sciences | New York, NY | Small Molecules |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| Boca Pharmacal | , | Bought by Qualitest |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| Glialogix | , | Gone Nov 2017 |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Gilson | Middleton, WI | Lab Supplies |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| SineuGene | Beijing, China | Gene Therapy |
| Cytopeia | , | Acquired by BD, May 2008 |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| , | Acquired by Maverix Medical, Dec 2023 | |
| , | Website down Jan 2026 - May 2026 | |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| Bracco | Milan, Italy | Imaging |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| bioMerieux | Cambridge, MA | Diagnostics |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Spirometrix | , | Renamed Spirosure |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| SpinalMotion | , | Website gone, 11-30-14 |
| Abbott | Mississauga, ON | Diagnostics |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
| Purinomia Biotech | , | |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| , | Website down Oct 2025 - Feb 2026 | |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Interferon Source | , | Bought by PBL Assay Science |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Metamark Genetics | , | Shut down 2018 |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Applied Integrin Sciences | , | Gone |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| Cobalis | , | Basically Bust |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Angelica Therapeutics | , | Gone 2018 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| STARLIMS | Hollywood, FL | LIMS |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| Inspirata | North York, ON | Cancer Insights |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Quartet Medicine | , | Wound down, Nov 2017 |
| , | Acquired by IMA Group, Oct 2025 | |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| BioDot | Irvine, CA | Equipment |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Niche Generics | Dublin, Ireland | Contract Generics |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| Brightflow Medical | Paris, France | Heart Failure Device |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| OcuDyne | , | AMD Medical Device |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Terumo Medical | Elkton, MD | Medical Devices |
| ClearView | Newton, MA | Strategic Consulting |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Micrologix Biotech | , | Renamed Migenix |
| Ketal Biomedical | , | Gone |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| , | Acquired by Glaukos, Aug 2025 | |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| Molecular Partners | Zurich, Switzerland | Biologics |
| RapidTrials | , | Pivoted to staffing, 2017 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| Spine View | , | Gone |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Aeres Biomedical | , | Gone Jul 2013 |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Idience | Seoul, Korea | Cancer Therapies |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| TaiwanBio | , | Website gone Oct 2021 |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Apaxis Medical | , | Gone 2019 |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| DNAMx | , | Renamed Adela |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| BioDatomics | , | Website gone Jan 2019 |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| Medallion Therapeutics | , | Shut down 2018 |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| neoSurgical | , | Shut down 2017 |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| Novotech | Seoul, Korea | Clinical Research |
| MicroVention | , | Now Terumo Neuro |
| Michrom | , | Bought by Bruker, Feb 2011 |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| Avivo BioOptics | , | Website down Dec 2022 |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Quanta Biosciences | , | Renamed QuantaBio |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Cell Technology | , | Acquired by ICT |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Accutome | , | Now part of Keeler |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Avalyn Pharmaceuticals | Cambridge, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| , | No news 2016 - Sep 2025 | |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| Octapharma | Springe, Germany | Plasma Products |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Masy Systems | , | fka Masy Biosystems |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| , | Website down Dec 2025 - Apr 2026 | |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| , | Acquired by Altaris, Mar 2025 | |
| Rhythm Health | , | Renamed Motus Therapeutics |
| , | Acquired by BioIVT, Aug 2024 | |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Trilobio | San Francisco, CA | Lab Automation |
| Mirador Biomedical | , | Shut Down 2019 |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| Exactech | Gainesville, FL | Medical Implants |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Proteom | , | Acquired by Amura Ltd |
| 89bio | Rehovot, Israel | Liver Treatments |
| Ameridose | , | Shut Down 2012 |
| Savage Medical | , | Renamed Averto Medical |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| SoBran | Falls Church, VA | Preclinical Services |
| Cellworks | South SF, CA | Biosimulations |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| Actavalon | , | Shut down Dec 2020 |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| AuraSense Therapeutics | , | Renamed Exicure |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Occam Design | Louisville, SS | Medical Device Development |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Genestack | Cambridge, UK | Genomics operating system |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| , | Website down Jan 2026 - May 2026 | |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Simpirica Spine | , | Became Empirical Spine |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| Regenerative Sciences | , | Took on Regenexx product name |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Iproteos | , | Products now with Accure Therapeutics |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Cellcion | , | Website gone, company going inactive |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Cancer Insight | , | Renamed LumaBridge |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| NIOX | Oxford, UK | Asthma management device |
| MSD | Ballydine, Ireland | Small Molecules |
| Nanosonics | Manchester, UK | Ultrasound |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Novo Nordisk | Beijing, China | Inflammation Research |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| , | Acquired by MasterControl, Mar 2025 | |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Auris Medical | , | Renamed Altamira Therapeutics |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Lupin | Baltimore, MD | Generics |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| , | Part of Genesis | |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Hypromatrix | , | Gone 2007 |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| Parabase Genomics | , | Presumed gone |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| AstraZeneca | Baar, Switzerland | Biologics |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| Kymanox | Morrisville, NC | Life Science Consulting |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| AVEO Oncology | Boston, MA | Small Molecules |
| ViraCyte | , | Renamed AlloVir |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| Beta-Pro | , | Now Triangle Research Labs |
| Surface Logix | , | Bought by Nano Terra |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| , | No news 2020 - Nov 2025 | |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Ascenta Therapeutics | , | Gone |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| Ekteino | , | Closed, Dec 2016 |
| Sharp | Allentown, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| , | Renamed Cellixx, May 2026 | |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| , | Website down Dec 2025 - May 2026 | |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| Furong Biotech | , | |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| Genoma | , | Website gone May 2021 |
| Nya Cell Therapeutics | , | No info |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Polytherapeutics | , | Gone Jun 2018 |
| Acumed | Beijing, China | Medical Implants |
| Riboxx | Dresden, Germany | RNA Products |
| Intact Genomics | St. Louis, MO | PCR kits |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Verséa Health | Tampa, FL | Diagnostics |
| DNALite Therapeutics | , | Renamed Particella |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| , | Website down Sep 2025 - Dec 2025 | |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| ATON | Shanghai, China | CDMO |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Huons | Seongnam, Korea | Small Molecules |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| Getinge | Feldkirchen, Germany | Medical Technology |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| , | Renamed Torpedo Therapeutics | |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| TRIFARMA | Chennai, India | APIs |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| Zephyr AI | McLean, VA | AI Data Analysis |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| Bacthera | , | Liquidating, Feb 2025 |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Ansata Therapeutics | , | Out of business 2007 |
| Iktos | Paris, France | AI for New Drug Design |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Cytiva | Tokyo, Japan | Medical Devices |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| Innovative BioTherapies | , | Gone |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Vessel Biosciences | , | Shut down Mar 2023 |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Chroma Medicine | , | |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MeiraGTx | London, UK | Gene Therapy |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Angel Biotechnology | , | Bankrupt, 2013 |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| , | Acquired by Xoma, Oct 2025 | |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| Alan Laboratories | , | Website gone, Jan 2019 |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| , | Seems to have shut down mid 2025 | |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Enzo Biochem | , | |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| Stemetix | , | Shut down Apr 2021 |
| , | Pandemic era government spongers | |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Endothelix | , | Now owned by American Heart technologies |
| , | Website down Aug 2025 - Jan 2026 | |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Sermes | Madrid, Spain | Full Service CRO |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| 206 Ortho | , | Shut down 2021 |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| ViroMed | , | Renamed Helixmith |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Develco Pharma | Schopfheim, Germany | Generics |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Grid Biosciences | New Territories, China | Vaccines |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| Compugen | Holon, Israel | Biologics |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Olio Labs | San francisco, CA | Software to de-risk clinical trials |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| , | Dissolved, Apr 2024 | |
| BioXpert | , | Website gone Mar 2017, employees gone |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Hope Medicine | Pudong, China | Antibody Therapy |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Medtronic | Mounds View, MN | Medical Devices |
| Ocis Biotechnology | , | |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| CTK Biotech | Poway, CA | Diagnostics |
| Emulate | Boston, MA | Organs-on-chips |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Alkermes | Wilmington, OH | Small Molecules |
| , | Website down Sep 2025 - Dec 2025 | |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| StemCell2MAX | , | Website gone Apr 2019 |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Cytoskeleton | Denver, CO | Research Products |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| , | Website down May 2025 - Dec 2025 | |
| Celemics | , | Gone Jul 2018 |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Phasiq | , | Website gone Jul 2018 |
| AccelaPure | , | Bankrupt 2007 |
| Thermo Fisher | Bend, OR | CDMO |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| Frenova | Waltham, MA | Renal clinical research |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Eyetech | , | Website Gone 6-16-12 |
| Omnia Biologics | , | Website gone Sep 2017 |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Therix Medical | , | Seems gone |
| Redoxis | Lund, Sweden | Drug development CRO |
| NantHealth | El Segundo, CA | Diagnostics |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Gengine | , | Renamed Editas Medicine, 2013 |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| , | Renamed Helyx Industries | |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Genencor | , | Bought by DuPont |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| LianBio | , | Winding down Feb 2024 |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Otsuka | Tokushima, Japan | Small Molecules |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| CP Life Science | , | Split and became Medvacon |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| Sequel Pharmaceuticals | , | Gone |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| Commave Therapeutics | , | |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| , | Website down Oct 2025 - Feb 2026 | |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Sharp | Lee, MA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| Hansa Medical | , | Renamed Hansa Biopharma |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| VaxInnate | , | Dissolved Feb 2017 |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Rgene | , | Late business filings Aug 2021 |
| MindRank | Shanghai, China | AI Drug Discovery |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| , | No news 2019 - Sep 2025 | |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Simbex | Lebanon, NH | Biomechanical devices |
| , | Dissolved Jun 2019 | |
| Intellimedix | , | Company founder/employee all moved on |
| Epigenos Biosciences | , | |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| , | Acquired by Instem, Jul 2025 | |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| Noscira | , | Liquidated |
| Avioq | Durham, NC | HIV Diagnostics |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| PrognosDx Health | , | Website gone Jun 2016 |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| rhealth | Bedford, MA | Diagnostics |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| Leading Pharma | Fairfield, NJ | Generics |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| SaluMedica | , | Website Gone Jul 2015 |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| DxNow | , | Renamed ZyMot fertility |
| Sundia | , | Part of BioDuro |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| , | Acquired by Millipore, Dec 2010 | |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| Infinity Bio | Baltimore, MD | Reactome Services |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| , | Acquired by Chiesi, Apr 2023 | |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| QT Vascular | , | Website gone Jan 2024 |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| CisThera | , | Shut down Jan 2023 |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Inno Biologics | , | Website gone Jun 2020 |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| BA Sciences | Morrisville, NC | Analytical Services |
| Emmes | Rockville, MD | Clinical Research Organization |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Bicolor | Belfast, UK | Lab Assays |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Univfy | Los Altos, CA | IVF reports |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| , | Renamed Carvolix, Feb 2026 | |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Artificial | Palo Alto, CA | AI Lab Platform |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| MitoStem | , | Seems gone |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Silktap | , | Liquid silk. Site gone |
| Cell Biosciences | , | Now ProteinSimple |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Adlyfe | , | Gone, no info |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| , | Website down Jul 2025 - Dec 2025 | |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Acumed | Madrid, Spain | Medical Implants |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| TaliaPharm | , | Website gone, Jan 2018 |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| ActivaTek | , | Acquired by North Coast Medical |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| OXON | Madrid, Spain | Real World Evidence |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| MicroPort | Shanghai, China | Medical Devices |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| VaxNewMo | , | Renamed Omiose |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Novasecta | London, UK | Pharma Consultancy |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Salvat | Miami, FL | Small Molecules |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| Alnis BioSciences | , | No info |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Curadev | Noida, India | Immuno-oncology |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| , | Acquired by Source BioScience, Apr 2025 | |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| , | Renamed First Atom Therapeutics | |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Viragen | , | Liquidated Oct 2007 |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Sonavex | Baltimore, MD | Ultrasound |
| , | Website down Oct 2025 - Feb 2026 | |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Myrexis | , | Liquidating 2013 |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Diverse Genomics | , | Website gone Jul 2020 |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| CMP Pharma | Farmville, NC | Small Molecules |
| PathoGene | , | Website taken over, Oct 2017 |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Zomanex | , | Gone Oct 2019 |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| METiS Technologies | , | |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| SutroVax | , | Renamed VaxCyte |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| Sentien Biotechnologies | , | Shut down late 2021 |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| CG Therapeutics | , | Dissolved Jul 2013 |
| , | Acquired by Fujirebio, 2022 | |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Kvvit Pharmaceutical | , | |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| ChemPacific | Baltimore, MD | Chemicals |
| Genemo | , | Seems inactive, Jul 2024 |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| Norton Scientific | , | Website Gone, Oct 2014 |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| Drugabilis | Villejust, France | Druggability Services |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Human Genome Sciences | , | Bought by GSK |
| , | Website down Jun 2025 - Dec 2025 | |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| SOLADIS | , | Acquired by Efor, 2021 |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| , | No news 2020 - Apr 2026 | |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| RegenoCELL Therapeutics | , | Presumed gone |
| Prominex | San Diego, CA | POC Diagnostics |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Élancé Therapeutics | , | Bispecific Antibodies |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| NeurAxon | , | No updates since 2008 |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Cardeas Pharma | , | Gone, 2017 |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| , | Acquired by HB Fuller, Jul 2023 | |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| , | Renamed Athens Bioscience, Mar 2026 | |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| , | Filings late Jun 2025 | |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Zai Lab | South SF, CA | Small Molecules |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Aresus Pharma | , | Seems folded in to Dermago |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Boston Scientific | St. Paul, MN | Medical Devices |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Avecris | Singapore, Singapore | Gene Delivery |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Gallus | , | Bought by Patheon, Aug 2014 |
| GIVAX | Boston, MA | GI Vaccines |
| , | Website down Jan 2026 - May 2026 | |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| Cytiva | Freiburg, Germany | Medical Devices |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| PLC Medical Systems | , | Renamed RenalGuard |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Sonus Pharma | , | Merged with Oncogenex |
| , | Shut down Dec 2025 | |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| Epixis | , | Acquired by VBI Vaccines |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| Pall | Port Washington, NY | Filtration |
| MilliporeSigma | Madison, WI | Small Molecules |
| Dynatherm Medical | , | Shut down 2012 or later |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| Santen | Osaka, Japan | Ophthalmics |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| Synedgen | Claremont, CA | Biofilm Control |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Aegea Biotechnologies | , | |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| Caidya | Raleigh, NC | Clinical Research Organization |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| STC Biologics | Newton, MA | Services |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Cirina | , | Merged with Grail, May 2017 |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| CoaguSense | Fremont, CA | Coagulation monitor |
| Taligen Therapeutics | , | Acquired by Alexion |
| , | Website down Dec 2025 - Feb 2026 | |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| Pear Bio | London, UK | Cancer Treatment Selection |
| Sorbent Therapeutics | , | Gone post 2014 |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Apotex | Toronto, ON | Small Molecule Generics |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Gilead | Mississauga, ON | Small Molecules |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Pirche | Grünwald, Germany | Transplant Matching |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| , | Renamed NeuraNova, Jan 2026 | |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| Novogene | Beijing, China | Genomic Services |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Bayer | Mexico City, Mexico | Small Molecules |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| , | Website down Aug 2025 - Jan 2026 | |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| , | Website down Jul 2025 - Jan 2026 | |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| ERT | , | Renamed Clario, Nov 2021 |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| BioMarin Pharmaceutical | London, UK | Biologics |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| Accellacare | Raleigh, NC | Clinical Research |
| Organogenesis | Canton, MA | Biologics |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| ECM Biosurgery | , | Website gone Sep 2022 |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| PharmacoFore | , | Now Signature Therapeutics |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Droice | New York, NY | AI Clinical Data |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| InvivoGen | San Diego, CA | Life Science Reagents |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Renamed ElisiGen, Dec 2025 | |
| Proxygen | Vienna, Austria | Cancer Therapies |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| KeraCure | , | Gone 2014 |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| TAI Diagnostics | , | Gone |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| Eversana | Chicago, IL | Commercialization Consulting |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| ISM Therapeutics | , | Website Gone, no response from employees |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| MerciaPharma | , | No updates 2014-2023 |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Hepalink | Shenzhen, China | Heparin API |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Bayer | Berlin, Germany | Small Molecules |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Apollomics | Xiaoshan, China | Cancer medicines |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Affymax | , | Dissolved 2014 |
| Adlon Therapeutics | , | |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Avax Technologies | , | Gone |
| , | Website taken over Jun 2026 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Marpē Therapeutics | , | Professor sideline |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Cure Foreward | , | Services suspended, May 2017 |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Altasciences | Laval, QC | Contract Research |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Quiescence Technologies | , | Website Gone |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Apieron | , | Shut down, May 2010 |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| Sanofi | Frankfurt, Germany | Small Molecules |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| Doctor Pack | Bangalore, India | Packaging |
| Alchemia | , | Gone, late 2017 |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| Abbott | Des Plaines, IL | Diagnostics |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| Bridge Laboratories | , | Gone 2013 |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| Climedo Health | Munich, Germany | Clinical Study Software |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| EyeTel Imaging | , | Gone Jul 2015 |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Indena | Milan, Italy | CDMO |
| Oxitope | , | Shut Down Feb 2019 |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| , | Renamed FocalOne, Feb 2026 | |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| ExcelseBio | , | Part of IntegrityBio |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| , | Renamed KadisBio | |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Kalypsys | , | Gone |
| Gene Logic | , | Bankrupt |
| Boston Neurosciences | , | Website down Jun 2020 |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Sampled | Motherwell, UK | Biostorage |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |