Taiwan - Biotech Companies - Career Pages
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
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Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Acucela | , | folded into Kubota Vision |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| Nanobiotix | Paris, France | Nanoparticles |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| VitamFero | , | Website gone Aug 2018 |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| Antyra | , | Gone |
| AstraZeneca | Boston, MA | Biologics |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| SVBio | , | Changed name to Lifecode |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
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Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| Kembiotix | , | No info, Aug 2022 |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| CG Therapeutics | , | Dissolved Jul 2013 |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| , | Website down Oct 2025 - Feb 2026 | |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
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Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Cellenion | Lyon, France | Single Cell Testing |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| Molsoft | San Diego, CA | Drug Design Software |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| TetraScience | Boston, MA | Scientific Cloud Software |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| Clinilabs | Eatontown, NJ | Clinical Research |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| LightMed | , | |
| Compass Biotech | , | Defunct |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| Amstem | , | SEC problems |
| Arecor | Little Chesterford, UK | Formulation Technology |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Hepalink | Shenzhen, China | Heparin API |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| , | Renamed Cyaris, Apr 2026 | |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| Mitokine Bioscience | , | Seems to be a research library now |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Apollo Scientific | Manchester, UK | Research Products |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Vista Scientific | , | Shut down Dec 2015 |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Leukosight | , | Gone, website is online pharmacy now |
| , | Website down Jun 2025 - Dec 2025 | |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Lunit | Seoul, Korea | AI Image Analysis |
| Epigen | , | Renamed Egenix, 2002 |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| ProPharma Group | Deerfield, IL | Consulting |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Prescos | , | Shut down Feb 2014 |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Biobase | , | Bought by Qiagen, May 2014 |
| NeuroPharm | , | Liquidated 2010 |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| Stryker | Salt Lake City, UT | Medical Devices |
| Elypta | Solna, Sweden | Liquid Biopsy |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| , | Renamed KadisBio | |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| Novahep | , | Website down, Oct-Dec 2017 |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Profil | Neuss, Germany | Clinical Research Services |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| , | Website down Oct 2025 - Feb 2026 | |
| Advaned Viral Research | , | Shut down 2009 |
| Siga | New York, NY | Small Molecules |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| Flux Biosciences | , | Shut down, ~2022 |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| Theracos | , | Renamed TheracosBio |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| AVEO Oncology | Boston, MA | Small Molecules |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Nascent Biologics | , | Changed to Nascent Biotech |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| CO.DON | Teltow, Germany | Cell Therapies |
| , | Acquired by Paradigm Health, Jan 2023 | |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| Octapharma | Lingolsheim, France | Plasma Products |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| BGI | Shenzhen, China | Genetic Testing |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| Curia | Hayward, CA | Contract Research |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| Amachumu Bio | , | Shut down April 2021 |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| , | Website down Jul 2025 - Dec 2025 | |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Indexus Biomedical | , | Shut down 2018 |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
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Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pharmexa | , | Merged into Affitech, May 2009 |
| , | Company gone Nov 2023, website taken by a game | |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| Meabco | , | |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| Endologix | Irvine, CA | Medical Devices |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| , | Website down Aug 2025 - Jan 2026 | |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| , | Shut down Sep 2025; fka GenoFAB | |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Z-Factor | , | Centessa Company |
| , | Website down Jan 2026 - May 2026 | |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| Covenant Therapeutics | , | Gone |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Atlas Genetics | , | Renamed Binx Health |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Alfasigma | Bologna, Italy | Small Molecules? |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| Bio-ops | , | Now SVA |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Diversa | , | Merged with Celunol to become Verenium |
| TransGenRx | , | Bankrupt |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
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Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| , | Acquired by Sebia, Sep 2024 | |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Berg | , | Acquired, Jan 2023 |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| , | Renamed BTgen Bio, May 2026 | |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Biomedica | , | Now part of Oxford Biomedica |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| , | Seems gone, Feb 2026 | |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Anazen Diagnostics | , | Part of Cardiox |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| , | Website down Jun 2025 - Dec 2025 | |
| Lumen Bioscience | Seattle, WA | Biologics |
| Modern Biosciences | , | Renamed Istisso |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| , | Renamed Cyclana Bio | |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| RFE Pharma | , | Gone 2019 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Totient | , | Acquired by Absci, Jul 2021 |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| One Drop | , | Gone Dec 2024 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Epic Sciences | , | Shut down May 2025 |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| Kentucky Bioprocessing | , | Now Kbio |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| SuperX | , | Gone |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| AccuVein | Medford, NY | Vein Visualization |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| , | No info 2019 - Mar 2026 | |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| restor3d | Durham, NC | 3D printed implants and devices |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| CEL-SCI | Vienna, VA | Biologics |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| Palo Alto, CA | Molecular Discovery Platform | |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Apath | , | No website update since 2014, Feb 2023 |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| , | Website down Jan 2026 - May 2026 | |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Haini Pharmaceutical | Shanghai, China | Generics |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| EGEN | , | Acquired by Celsion, Jun 2014 |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| , | Shut down 2024 | |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| Attenuon | , | Now Tactic |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Serotiny | , | Acquired by J&J, 2023 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| , | Acquired by Kite, Aug 2025 | |
| Novartis | Emeryville, CA | Diagnostics |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Nanobac Pharmaceuticals | , | Gone |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| Catalyz | , | Gone |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| CoaguSense | Fremont, CA | Coagulation monitor |
| LabTwin | , | Merged with Labforward |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| GeneTrol | , | Merged with CytoPharm |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| , | Website down Sep 2025 - Jan 2026 | |
| Frenova | Waltham, MA | Renal clinical research |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Corza Medical | Somerset, UK | Surgical Devices |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| Advanz Pharma | London, UK | Specialty Generics |
| Keenova | Bridgewater, NJ | Small Molecules |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| LabConnect | Johnson City, TN | Lab Services |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Cologne, Germany | Surgical Simulation | |
| SoftGenetics | State College, PA | Software for genetic analysis |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| Ho’ola Therapeutics | , | |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Delpharm | Orléans, France | Contract Manufacturing |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| Delta Pharma | , | Renamed Randstadt Pharma |
| ChronTech Pharma | , | Became real estate company |
| RecomGenex | , | Renamed TargetEx Biosciences |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| CTIBIOTECH | Philadelphia, PA | Tissue Sample |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| Alan Laboratories | , | Website gone, Jan 2019 |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| Curadigm | , | folded into Nanobiotix |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Sepracor | , | Now Sunovion |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
 |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Quintessence Biotech | , | Biomimetic Separation |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| Virvio | , | Gone Feb 2020 |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| X2 Pharma | , | Website Gone |
| Par Health | St. Louis, MO | Generics |
| Bioneeds | Bangalore , India | Contract Research |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Jerini | , | Acquired by Shire, 2008 |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Cognis Corp | , | Acquired by BASF 2010 |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| , | Acquired by Instem, Jul 2025 | |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| Pulse Biomedical | , | Distributor |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| Macrocure | , | Merged into Leap Therapeutics |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| PRI Research | , | Renamed Wake Clinical |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| , | Shut down June 2024 | |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Pristine Bioproduction | , | Not a going concern |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Axcend | Lehi, UT | Chromatography Services |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| , | Acquired by Collate, Aug 2025 | |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Abbott | Des Plaines, IL | Diagnostics |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| Genometry | , | Shut down Dec 2019 |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| , | Renamed Pixl.bio, Nov 2025 | |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| , | business filings late Oct 2023 - Oct 2025 | |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| Validation Associates | Herndon, VA | Validation Consulting |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| LexaMed | Toledo, OH | Life Science Consulting |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Creative Bioinformatics Consultants | , | Gone |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| ImmunArray | , | Shut Down, 2021 |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| , | Shut down Dec 2025 | |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Sermes | Madrid, Spain | Full Service CRO |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Evocutis | , | Pivoted to investments |
| COR Clinical Research | , | Shut down after owner passed |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| Arzeda | Seattle, WA | Computation protein design |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| , | Website down Jan 2026 - May 2026 | |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| Nanosonics | Indianapolis, IN | Ultrasound |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Niagara Biosciences | , | No info, Aug 2022 |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| Alerchek | , | Closed late 2016 |
| Proxima | New York, NY | AI Protein Folding Platform |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Noble | Orlando, FL | Auto-injector Trainers |
| Avam | Odessa, FL | Clinical Diagnostics |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Verus Pharmaceuticals | , | Dissolved |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| , | Acquired by Uniphar | |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Protein Polymer Technologies | , | Basically Gone |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Protein Forest | , | Bought by Cell Biosciences |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Onorach | Dundee, UK | Clinical Trial Management |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Gilson | Middleton, WI | Lab Supplies |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| OncoCell MDx | , | Renamed Immunis.AI |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| SeqRight | , | Acquired by GE Apr 2012 |
| Catamaran Bio | , | Winding down Jan 2024 |
| , | Gone Jan 2026 | |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| PluriCell | , | Renamed LizarBio |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| EnquBio | San Diego, CA | Contract Research & Services |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Apollomics | Foster City, CA | Cancer medicines |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| , | Website down Dec 2025 - Apr 2026 | |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| InteguRx | , | Website taken over, Dec 2023 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Microbiotix | Worcester, MA | Small Molecules |
| Reserva | , | Renamed NeurMedix, 2016 |
| , | Website down Jul 2025 - Jan 2026 | |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| , | Acquired by HB Fuller, Jul 2023 | |
| , | Website down Oct 2025 - Dec 2025 | |
| Scinomix | Earth City, MO | Lab Automation Products |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Alkem Labs | Mumbai, India | Generics |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| CNS Research | , | Seem gone, 2020 |
| Zenosense | , | No website, shell company Nov 2020 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| , | DNA origami nanotechnology | |
| , | Acquired by IQVIA | |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| Orthologic | , | Now Capstone Therapeutics |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| MWG Biotech | , | Owned by Eurofins |
| OmniBiome Therapeutics | , | Gone 2014? |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Cyto360 | , | Website gone Aug 2018 |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Caidya | Raleigh, NC | Clinical Research Organization |
| Qbiogene | , | No website. Fisher sells their products |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Website down Nov 2025 - Apr 2026 | |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| , | Website down Oct 2025 - Feb 2026 | |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Denk Pharma | Munich, Germany | Generics |
| PRACS Institute | , | Bankrupt 2013 |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
 |
Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Hematogenix | Tinley Park, IL | Pharma Services |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Angiosonics | , | Shut down 2002 |
| Amplified Proteomics | , | Shut down Jan 2006 |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| Emmes | Rockville, MD | Clinical Research Organization |
| Oxis International | , | Renamed GT Biopharma |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Takara Bio USA | San Jose, CA | Lab products |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Blue Cross Laboratories | Mumbai, India | Generics |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| , | Website down Jan 2026 - May 2026 | |
| Ipsen | Signes, France | Small Molecules, Biologics |
| , | Website down Sep 2025 - Feb 2026 | |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Devsynthesis | Austin, TX | Chemistry CRO |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
 |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Helsinn | Dublin, Ireland | Small Molecules |
| Ezose Sciences | , | Rebranded as S-bio |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| ClearView | Newton, MA | Strategic Consulting |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| , | Website down Jan 2026 - May 2026 | |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Bio Processing | , | Bought by Bio-rad |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| , | Shut down 2025 | |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Curia | Buffalo, NY | Contract Research |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| Tyrian Diagnostics | , | Gone 2012 |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Active Pass Pharmaceuticals | , | Gone |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| Hua Medicine | Shanghai, China | Small Molecules |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Abbott | Donegal, Ireland | Diagnostics |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| NetBio | , | Renamed ANDE |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| Grunenthal | Origgio, Italy | Small molecules |
| Carver Biosciences | , | |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Bracco | Monroe Township, NJ | Imaging |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| JustRight Surgical | , | Renamed Bolder Surgical |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Perceptive | Nottingham, UK | Medical Imaging |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
 |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Recensa Therapeutics | , | Only employee gone 2018 |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| Integer | Plano, TX | Medical & Surgical Devices |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Calmune | , | Liquidated |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Quanta Biosciences | , | Renamed QuantaBio |
| OD-OS | Irvine, CA | Retinal Laser |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Covaris | Woburn, MA | DNA Sample Prep |
| Hookipa Biotech | , | Now Hookipa Pharma |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| ProtonDx | London, UK | Diagnostics |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Prime Biologics | , | Seems gone 2019 |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Asuragen | Austin, TX | Diagnostics |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Reach Separations | Nottingham, UK | Purification Services |
| V-gene | , | Website gone, Aug 2017 |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| WestGene | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| COOL-BIO | , | Gone |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| , | No news 2019 - Sep 2025 | |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| BEAT BioTherapeutics | , | Closed 2017 |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Coldstream Laboratories | , | Bought by Piramal |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Exelixis | Alameda, CA | Small Molecules |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Neurogene | Houston, TX | Genetic Therapies |
| NIOX | Oxford, UK | Asthma management device |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| Champions Biotechnology | , | Now Champions Oncology |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Cellink | Gothenburg, Sweden | Bioprinting |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| , | ||
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Alvea | , | Shut down Oct 2023 |
| , | Dissolved Jun 2019 | |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| Affymax | , | Dissolved 2014 |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Abnovel | , | Gone Jul 2010 |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| BioChain | Newark, CA | Sample Preparation |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| Zumutor Biologics | Bangalore, India | Biologics |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| Kallyope | New York, NY | Gut-brain axis focus |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| Curadev | Kent, UK | Immuno-oncology |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Exactech | Gainesville, FL | Medical Implants |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| , | Renamed PKx Bio, 2026 | |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| Destiny Pharma | Brighton, UK | Antimicrobials |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| , | Website down Oct 2025 - Feb 2026 | |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| Ipsen | Sumter, SC | Biologics |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Axcella Health | , | Renamed Axcella Therapeutics |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| MiniVax | , | Gone Jan 2016 |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| DC Biosciences | , | Shut down Jul 2023 |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Greenstone Biosciences | Palo Alto, CA | |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| SYNkinase | , | Shut down |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Amigenics | , | Gone |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| SJ Pharma | , | Website gone, Nov 2018 |
| MiniMed | Northridge, CA | Diabetes Management |
 |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| , | Acquired by Merck, May 2026, $6.67B | |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
 |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Molecular Logix | , | Gone, Dec 2018 |
| AxioMed | , | President left in 2018, not registered in MA |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| Photonion | Schwerin, Germany | Analytical Equipment |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| Valitor | Berkeley, CA | Protein therapeutics |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Labopharm | , | Bought by Paladin 2011 |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| MSD | Brinny, Ireland | Small Molecules |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| SiliCycle | Québec, QC | Separation Technologies |
| Amaranth Medical | , | Website gone, Apr 2019 |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| , | Renamed ExGen Dx, Jul 2025 | |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| , | Renamed SylamoreBio | |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| APT Therapeutics | , | Shut down Mar 2019 |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| Penwest | , | Bought by Endo |
| HCW Biologics | Miramar, FL | Immunotherapy |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| In Veritas Medical Diagnostics | , | Shell company |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| Amakem | , | Website gone Dec 2015 |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| Castor | Claymont, DE | eClinical Trial Software |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Progenika | , | Bought by Grifols |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Regenica Biosciences | , | Gone Nov 2020 |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| BenuBiopharma | , | Shut down Sep 2023 |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Vega Therapeutics | , | Part of Star Therapeutics |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| MOgene | St. Louis, MO | Genomic Services |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Elucid | Boston, MA | Arterial Analysis Software |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| ImmBio | , | Shut down Nov 2019 |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| ObsEva | , | Shut down Feb 2024 |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Stelvio Oncology | , | Gone late 2019 |
| Rox Medical | , | Gone 2019 |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| amcure | , | Liquidated Sep 2024 |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Refeyn | Oxford , UK | Mass Photometry |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| Ocean Therapeutics | , | Shut down June 2013 |
| GlycoEra | Boston, MA | Custom Glycan Platform |
| Serentrix | , | Seems gone Apr 2022 |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| ModeX Therapeutics | Weston, MA | Biologics |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Celvive | , | No news from 2012-2020 |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| , | Shut down late 2025 | |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| Sanofi | Haverhill, UK | Small Molecules |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Cytecs | Münster, Germany | Cell Analysis |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| PsiOxus Therapeutics | , | |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Nanoferix | , | Renamed Pendant Biosciences |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| MilliporeSigma | Madison, WI | Small Molecules |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| Cydan Development | , | Shut down Sep 2021 |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| Alliances Catalyst | , | Liquidated |
| Novelty Nobility | Seongnam, Korea | ADCs |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| Calchan | , | Shut down Dec 2020 |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| Mepha | Basel, Switzerland | Generics |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| , | Acquired by StarFish Medical, Nov 2024 | |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| 3B BlackBio | Bhopal, India | PCR products |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| VALOS | Genova, Italy | Clinical Statistics |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Inductive Bio | Virtual, US | Compound Optimization |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| , | Website down Oct 2025 - Feb 2026 | |
| General Oncology | Brookline, MA | Cancer Therapies |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Medrio | San Francisco, CA | Clinical Trial Software |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| , | Website down Oct 2025 - Feb 2026 | |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| , | Website down Jun 2025 - Dec 2025 | |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| , | Website down Jan 2026 - May 2026 | |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| SE3D | , | Renamed Seed Therapeutics |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Curia | Buffalo, NY | Contract Research |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| Vernacare | Blackwood, UK | Surgical Devices |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| DP Clinical | Rockville, MD | Clinical Research |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Novotech | Taipei, Taiwan | Clinical Research |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| , | Acquired by BioIVT, Aug 2024 | |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| CultureTrax | , | Shut Down Dec 2019 |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Biovays | , | Website Gone |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| Xegen | Gemenos, France | NGS Data Analysis |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Vyriad | Rochester, MN | Immunovirotherapy |
| IQVIA | Durham, NC | Clinical Research |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| Lupin | Goa, India | Generics |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Medivector | , | Gone late 2018 |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| CBM Biopharma | , | Shut down Nov 2020 |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Ketal Biomedical | , | Gone |
| Genomas | , | Website gone May 2020 |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Abviva | , | Gone, 2008 |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Taxolog | , | Website gone, Nov 2015 |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| CorDx | San Diego, CA | Diagnostics |
| Squarex | , | Gone as of Oct 2021 |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| PharmatrophiX | , | No news 2015 - Sep 2025 |
| Algenics | , | Website gone Dec 2015 |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Grid Biosciences | New Territories, China | Vaccines |
| Accellacare | Downers Grove, IL | Clinical Research |
| Northstar Neuroscience | , | Dissolved |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| BionX Medical | , | Acquired by Ottobock |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Stada | Bad Vilbel, Germany | Generics |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Interferon Source | , | Bought by PBL Assay Science |
| Inexia | , | Acquired by Centessa |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| Cytopeia | , | Acquired by BD, May 2008 |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Delpharm | Tours , France | Contract Manufacturing |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| DL Develop | , | Website gone, Dec 2018 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| Curevo Vaccine | Bothell, WA | Vaccines |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| Ximedica | Plymouth, MN | Medical Device Services |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| , | Shut down Nov 2025, Tempus acquired assets | |
| Predictive Biosciences | , | Closed 2013 |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| Imeka | Sherbrooke, QC | Neuroimaging |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Gran Med | , | Gone |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Advansta | San Jose, CA | Protein characterization products |
| Aixa Bio | Cambridge, MA | AI genomics |
| Abiologics | Cambridge, MA | Synteins |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Silence Therapeutics | Berlin, Germany | RNAi |
| ADS Biotechnology | , | Bankrupt 2014 |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Roche | Buonas, Switzerland | Diagnostics |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| Qurasense | , | Renamed Qvin |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| , | Website down Jan 2026 - May 2026 | |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Advanced Genetic Technologies | , | No info |
| BioMarin Pharmaceutical | London, UK | Biologics |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| , | Website down Sep 2025 - Dec 2025 | |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| Biomax Informatics | , | Acquired by Labvantage |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Droice | New York, NY | AI Clinical Data |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| NanoSort | , | Renamed NanoCellect |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Curadev | Noida, India | Immuno-oncology |
| , | Website down Oct 2025 - Jan 2026 | |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Piramal | Mahad, India | CDMO |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| CranioVation | , | Shut down Jan 2022 |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| , | Acquired by hVIVO, Dec 2019 | |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| Alkermes | Dublin, Ireland | Small Molecules |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| Surface Logix | , | Bought by Nano Terra |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Terumo Medical | Elkton, MD | Medical Devices |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| Advancells | Noida, India | Stem Cell Treatments |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| , | Website down Aug 2025 - Jan 2026 | |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| GeneEx | , | Now RevDia |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
 |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| IQVIA | Lenexa, KS | Clinical Research |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| ApniCure | , | Gone 2017 |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Ablacon | , | Shut down Mar 2024 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| , | Winding down Apr 2026 | |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| BioGaia | Stockholm, Sweden | Probiotics |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Getinge | Mahwah, NJ | Medical Technology |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Prolexys Pharmaceuticals | , | Website Gone |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| TAI Diagnostics | , | Gone |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| , | Part of ICE Pharma | |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| Eversana | Chicago, IL | Commercialization Consulting |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Nanovelos | , | Subsumed into Nanogroup |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Tryton Medical | , | Shut down Jan 2021 |
| Beardsworth | , | Bought by TFS International 2013 |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| , | Website down Jun 2025 - Dec 2025 | |
| ProPharma Group | Washington, DC | Consulting |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| ParinGenix | , | Gone, 2012? |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Life Couriers | Munich, Germany | Diagnostics |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Cambria Biosciences | , | Gone Feb 2008 |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| Borean Pharma | , | Gone |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Otsuka | Rockville, MD | Small Molecules |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| Virometix | Schlieren, Switzerland | Vaccines |
| , | Website down May 2025 - Jan 2026 | |
| nference | Cambridge, MA | Clinical AI |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| , | Acquired by Altivera Medical, Mar 2026 | |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| , | Acquired by RTI Surgical , Nov 2024 | |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| Cobalis | , | Basically Bust |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| AmplifyBio | , | Shut down Apr 2025 |
| Glysantis | , | Shut down Late 2020 |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| Microphage | , | Bankrupt Jun 2013 |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Promaxo | Oakland, CA | Small form MRI |
| Diality | Irvine, CA | Hemodialysis System |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Kastle Therapeutics | , | Closed May 2018 |
| Avatar Biotechnologies | , | Gone 2010 |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| , | Gone Sep 2025 | |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Apollomics | Xiaoshan, China | Cancer medicines |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Rubix Device | , | Website gone, Aug 2017 |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| , | Gone before Dec 2025 | |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
 |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| Mediso | Budapest, Hungary | Medical Imaging |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Argolight | Pessac, France | Microscopes |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| SegAna | , | Website down May 2021 - Sep 2021 |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Phase Forward | , | Bought by oracle |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Gilead | Edmonton, AB | Small Molecules |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Parsolex | , | |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| BBB Therapeutics | , | Bankrupt 2015 |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Syndexa Pharm | , | Closed Jul 2013 |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| VG Life Sciences | , | Shell company |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| , | Pivoted to defense, Feb 2026 | |
| OD-OS | Teltow, Germany | Retinal Laser |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| Evofem Biosciences | San Diego, CA | Women's health |
| Bioxene | , | Website gone, Company Presumed gone |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| EsbaTech | , | Bought by Alcan |
| Axplora | Chennai, India | API manufacturing |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Inno Biologics | , | Website gone Jun 2020 |
| , | Website down Aug 2025 - Jan 2026 | |
| Cellf BIO | , | Website taken over Jan 2019 |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| NIOX | Morrisville, NC | Asthma management device |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| Ansh Labs | Webster, TX | Diagnostics Products |
| , | Website down Oct 2025 - Feb 2026 | |
| Universal Precision Instruments, Inc. | , | |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| GliaGen | , | Renamed CaCy Therapeutics |
| VitalMedix | , | Out of Money 2010 |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Menarini | Dresden, Germany | Small Molecules |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Celixir | , | Shell acquired Dec 2023 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Bakhu Pharma | , | Bankrupt, location sold |
| Alimentiv | San Diego, CA | Clinical Services |
| Nasseo | , | Gone |
| Logan Medical Devices | , | Gone? |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| Activated Cell Therapy | , | Changed name to Dendreon |
| , | Acquired by Syner-G BioPharma Group | |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| Genyro | San Francisco, CA | DNA Construction Technology |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| RION | Rochester, MN | Exosome Therapeutics |
| BioSyntech | , | Bought by Piramal |
| Cordis | Miami Lakes, FL | Medical Devices |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Ana-Gen Technologies | , | Gone post 2001 |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| , | Website down Jul 2025 - Dec 2025 | |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| TRIFARMA | Chennai, India | APIs |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| Zetra Biologicals | , | Gone |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Endogenx | , | Website Gone Dec 2013 |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Teva | Toronto, ON | Small Molecules |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Microbia-pe | , | Renamed Microbia |
| Medtronic | Cincinnati, OH | Medical Devices |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| SynAm Vaccine | , | Gone 2017 |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Laureate Pharma | , | Acquired by Gallus |
| , | Renamed Valion Bio, Apr 2026 | |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| Createrna Science | Shanghai, China | Small Molecules |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| MedCision | , | Assets bought by MedCision, May 2018 |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Tisucor | , | Shut down Feb 2020 |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| , | Website down Jan 2026 - May 2026 | |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| OBDURO Biotechnologies | , | never a registered CA business |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| AsymBio | Jinshan, China | Biologics CDMO |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| , | Acquired by AbbVie, Aug 2025 | |
| IQVIA | Durham, NC | Clinical Research |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Catawba Research | Charlotte, NC | Clinical Research |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Accugent Laboratories | , | Website gone Sep 2017 |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| Neuroptix | , | Renamed Cognoptix |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| , | Renamed Daisy Genomics, Dec 2025 | |
| SDIX | Newark, DE | Diagnostics |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| , | No news 2019 - Oct 2025 | |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Synfini | Menlo Park, CA | AI Drug Design |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Divide and Conquer | , | Website gone Mar 2024 |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| AGI Therapeutics | , | Bought by Videra |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Piramal | Turbhe, India | CDMO |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| Brilliant Research | , | Website gone Dec 2018 |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| PharmaDerm | , | Part of Sandoz |
| Roche | Tucson, AZ | Diagnostics |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| Alchemia | , | Gone, late 2017 |
| SolaranRx | , | Website taken over |
| Essential Pharma | Egham, UK | Generics |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Molecular Sensing | , | Business revoked Aug 2019 |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Dante Labs | , | Seems to be Dante Genomics now |
| DermBiont | Boston, MA | Topical Bacterial Products |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Veracyte | South SF, CA | Cytology Diagnostics |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| PrognosDx Health | , | Website gone Jun 2016 |
| Apobiologix | Toronto, ON | Biosimilars |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Maxwell Biosciences | Austin, TX | Antivirals |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Cytokinetics | South SF, CA | Small Molecules |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Integer | Chaska, MN | Medical & Surgical Devices |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Applied Molecular Genetics | , | Renamed Amgen |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| Ribonomics | , | Sold to MBL International |
| Altasciences | Overland Park, KS | Contract Research |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Mustang Bio | Worcester, MA | Immunotherapies |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Genitope | , | Wound Down |
| SOCIUM | Tokyo, Japan | Contract Research |
| Actera Pharmaceuticals | , | Closed |
| , | Acquired by Instem, Jul 2025 | |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| |
Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| , | Website down Jan 2026 - Apr 2026 | |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Apgene Bio | , | Shut down Oct 2020 |
| Curia | Hopkinton, MA | Contract Development, Manufacturing |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Acidophil | , | Gone late 2022 |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| , | Liquidation, Jun 2025 | |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Allometra | , | Gone |
| Pharmaron | Hertfordshire , UK | R&D Services |
| Chrysalis | Waltham, MA | GMP Space |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| , | Website down Oct 2025 - Feb 2026 | |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| Hikma | London, UK | Medication Delivery |
| Westat | Rockville, MD | Clinical trial design, management, services |
| , | Website down Oct 2025 - Feb 2026 | |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| Mendelian | London, UK | Rare Disease Diagnosis |
| Hoth Therapeutics | New York, NY | Small Molecules |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| , | Acquired by Instem, Jul 2025 | |
| Xtuit | , | Gone Jul 2018 |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Breathometer | , | Product didn’t work, pivoted |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| Proacta | , | Gone 2014 |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| STB Lifesaving Technologies | , | Website gone |
| Oncogen | , | Acquired by BMS, 1986 |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| BioRelix | , | Restructured. Unknown Status. |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| , | Website down Aug 2025 - Jan 2026 | |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| , | Website down Jun 2025 - Dec 2025 | |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Inspirata | Tampa, FL | Cancer Insights |
| GenEndeavor | Hayward, CA | Diagnostics |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| Medtronic | Mounds View, MN | Medical Devices |
| RegeneraTEch | , | Renamed Regencor |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| Ingenetix | Wien, Austria | PCR Products |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| August Bioservices | Nashville, TN | Research & Development Services |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| Martek Biosciences | , | Bought by DSM |
| AlphaGenix | , | Gone 2014 |
| Medtronic | Shoreview, MN | Medical Devices |
| Accelrys | , | Bought by Dassault, 2014 |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Sonosine | Kidlington, UK | Medical Imaging |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| Sanovel | Silivri, Turkey | Generics |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| Biocodex | Gentilly, France | Microbiota Treatments |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| Assay Designs | , | Now Enzo Life Sciences |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Bicolor | Belfast, UK | Lab Assays |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| C3 Jian | , | Now C3J Therapeutics |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| RetiPharma | , | Dissolved Nov 2019 |
| Liposonix | , | Bought by Medicis |
| HEC | , | Website down Dec 2024 - May 2025 |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Crown Bioscience | San Diego, CA | Drug Development |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| Excelsyn | , | Bought by AMRI |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| ExcelseBio | , | Part of IntegrityBio |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| ConquerX | , | Dissolved Jun 2021 |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| InteKrin | , | Owned by Coherus Biosciences |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| Intellikine | , | Bought by Millennium 2011 |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| , | Acquired by Novacyt Group | |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| SourceMDx | , | Assets Sold |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| MeiraGTx | London, UK | Gene Therapy |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Padagis | Allegan, MI | Generics |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Cedilla Therapeutics | , | Shut down May 2023 |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| nitec Pharma | , | Merged with Horizon Pharma |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| CellCarta | Montréal, QC | Clinical Research |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
 |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Adroit Surgical | , | Defunct |
| , | Website down Nov 2025 - Mar 2026 | |
| Niramai | London, UK | AI-breast cancer detection device |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Panther Orthopedics | , | Shut down Dec 2022 |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Verana Health | San Francisco, CA | Clinical Database |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Lectus Therapeutics | , | Sold off product |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| Tactic Pharma | , | Website gone, Apr 2018 |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Biogenes | Berlin, Germany | Antibodies |
| Hybrigenics | , | Renamed ATON |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| LinkChem | Shanghai, China | CDMO |
| Coordination Therapeutics | , | Not Active |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| Senzime | Uppsala, Sweden | Devices |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| MediLink Therapeutics | Suzhou, China | ADC |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| Hope Medicine | Pudong, China | Antibody Therapy |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| , | No news 2021 - Apr 2026 | |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| Ximedica | San Francisco, CA | Medical Device Services |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| bioTHER | , | Gone |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| Elan | , | Bought by Perrigo, Dec 2013 |
| Salvat | Madrid, Spain | Small Molecules |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| Organogenesis | Canton, MA | Biologics |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Piramal | Ennore, India | CDMO |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| , | Acquired by IQVIA | |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| TranS1 | , | Renamed Baxano Surgical |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Ativa Medical | , | Renamed Immune IQ? |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| Ipca Laboratories | Mumbai, India | APIs |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| OrthoData | , | Renamed Intellirod Spine |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Akela Pharma | , | Now PharmaForm |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Analogic | Peabody, MA | Medical Imaging |
| TRIFARMA | Rozzano, Italy | APIs |
| Celerion | Belfast, UK | Clinical Research |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| NextPharma | London, UK | Contract Research & Development |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| PregLem | , | Acquired by Richter, Oct 2010 |
| Panaxia | Lod, Israel | Medical Cannabis |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| Aytu BioScience | , | now Aytu BioPharma |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Nuvelution Pharma | , | Gone 2020 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| RQM+ | Monroeville, PA | Regulatory compliance consulting |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| , | No news 2021 - Sep 2025 | |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| , | part of ElevateBio; fka LifeEDIT | |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| SoBran | Falls Church, VA | Preclinical Services |
| QT Ultrasound | , | Renamed QT Imaging |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| SilaGene | , | Gone |
| MedinCell | Jacou, France | API Delivery Gel |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| Allelix | , | Merged with NPS |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| Chaperone Therapeutics | , | Gone 2019 |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Calypte Biomedical | , | Gone |
| Neoantigenics | , | Website gone Sep 2017 |
| Alfama | , | Merged into Proterris, May 2017 |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| AzurRx | , | Merged into First Wave Bio |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Bionovica | , | Website gone Dec 2022 |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| ABL | Lyon, France | Viral Vector CDMO |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| Stago | Taverny, France | Diagnostics |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| BioSpherex | , | Renamed Metabiomics |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Nabla Bio | Cambridge, MA | Antibody Design |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Nesher Technologies | , | Shut down Oct 2017 |
| Accellacare | Hickory, NC | Clinical Research |
| Roche | Mississauga, ON | Small Molecules |
| Panakeia | Cambridge, UK | in silico multi-omics |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Biodel | , | Merged with Albireo, Oct 2016 |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Carticept Medical | , | Dissolved Feb 2020 |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| , | 16 years in, CMO is CEO elsewhere Dec 2025; fka Glycoregimmune | |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| Navinta | Ewing, NJ | Generics |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| , | Acquired by Xoma, Nov 2025 | |
| Ackley Hartnett | Moorestown, NJ | Tablet Machines |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Purdue Pharma | Wilson, NC | Small Molecules |
| AbbVie | Dublin, Ireland | Medical Devices |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Origen Therapeutics | , | Gone |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| Clario | Philadelphia, PA | Clinical Services |
| Haupt Pharma | , | Merged with Aenova |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Piper Therapeutics | , | Website gone May 2020 |
| TandemAI | New York, NY | AI to democratize the drug development process |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Dipharma | Baranzate, Italy | APIs, Generics |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Qynapse | Boston, MA | Imaging Analysis |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
 |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| Helix | San Mateo , CA | Genetic Testing |
| , | Renamed Peritia, Jan 2026 | |
| Aikium | Berkeley, CA | AI Drug Discovery |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| ProtAffin | , | Winding Down |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Vivex Biologics | Atlanta, GA | Tissues |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| mAbRx | , | Gone |
| JCL Bioassay | , | Renamed CMIC |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Pharmaron | Tianjin, China | R&D Services |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Nensius Research | , | Website Gone |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Transmed Oncology | , | Gone? |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Accellacare | Salisbury, NC | Clinical Research |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| , | No news 2019 - Jan 2026 | |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| RJS Biologics | , | Shut down Feb 2019 |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Glenmark | Mumbai, India | Generic Small Molecules |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Innerpulse | , | Gone maybe 2013 |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| , | ||
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
 |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| American Regent | Shirley, NY | Generics |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| , | Website down Dec 2025 - Apr 2026 | |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| Stemnovate | Cambridge, UK | Research Cells |
 |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| R/D Clinical Research | , | Website Gone |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Auris Medical | , | Renamed Altamira Therapeutics |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Veeva Systems | Toronto, ON | Life Science Software |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| MediWound | Yavne, Israel | Wound & Burn Care |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| MitoStem | , | Seems gone |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| Bonenta | , | Website gone |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Analog Pharma | Princeton, NJ | Generics |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Alacrity Biosciences | , | Gone post-2011 |
| Gen-probe | , | Acquired by Hologic 2012 |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| TG Therapeutics | Morrisville, NC | Biologics |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| , | Website down Dec 2025 - Apr 2026 | |
| Maroon Biotech | , | Gone Sep 2010 |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| Resilience | Mississauga, ON | Biomanufacturing |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| TissUse | Berlin, Germany | Multi Organ chip |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| Interdict | San Francisco, CA | Small Molecules |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis la |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| Ganymede | Palo Alto, CA | Lab Automation |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| , | Website down Aug 2025 - Jan 2026 | |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| NEC Oncoimmunity | , | Renamed NEC |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Biotox Sciences | , | Renamed BTS Research |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| Amarin | Dublin, Ireland | Small Molecules |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Cellcion | , | Website gone, company going inactive |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Brain Vision | Morrisville, NC | EEG Systems |
| NormOxys | , | Gone |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Novoresearch | , | Gone 2014 |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| , | Website down Jan 2026 - May 2026 | |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| Vision Medicines | , | Gone 2017 |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| , | Website down Nov 2025 - Apr 2026 | |
| Eos Biotechnology | , | Gone 2005 |
| Concerto HealthAI | , | Renamed ConcertAI |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| iWel | Exton, PA | Glucose Meters |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Bionode | , | Shut down Mar 2024 |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| , | Liquidating, Sep 2025 | |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| Biosion | Nanjing, China | Bispecific Antibody |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Rhythmedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| , | Renamed Ribonexus, Nov 2021 | |
| |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| , | Part of Evogene | |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| Hologic | Beijing, China | Diagnostic, Imaging |
| NeuroTherapeutics | , | Gone |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| miR Scientific | , | Renamed miRNA Scientific |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| Ossis | , | 3D-printed orthopedic implants |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| DxTerity | Torrance, CA | Genomic Testing |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| Chanelle Pharma | London, UK | Generics |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| , | ||
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Assurance Scientific Laboratories | Austin, TX | Molecular Technologies |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Akubio | , | Bankrupt Sep 2007 |
| Novotech | Seoul, Korea | Clinical Research |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| Glen Research | Sterling, VA | Oligos |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| JABio | , | Shut Down May 2021 |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Rytvel Biotechnology | , | |
| Genfit | Loos, France | Drug Discovery |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Meissner | Camarillo, CA | Lab Systems |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| Bioenza | , | Website gone Sep 2017 |
| Talima Therapeutics | , | Closed 2011 |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| , | Acquired by Epitype, Oct 2025 | |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| AtriCure | Mason, OH | Cardiovascular Devices |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| Cytiva | Tokyo, Japan | Medical Devices |
| Bioserv America | , | Shut down Aug 2024 |
| Protein Design Labs | , | Renamed PDL Biopharma |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Heart Repair Technologies | , | |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Protypia | , | |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Virco | , | Bought by J&J |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| ISM Therapeutics | , | Website Gone, no response from employees |
| Sytera | , | Merged with Sirion Aug 2006 |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| , | Website down Jan 2026 - May 2026 | |
| Getinge | Växjö, Sweden | Medical Technology |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| Hansa Medical | , | Renamed Hansa Biopharma |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| Alverix | , | Acquired by BD, Jan 2014 |
| Xencor | Pasadena, CA | Antibody Discovery |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Avax Technologies | , | Gone |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| Gen Plus | Munich, Germany | Formulation |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| , | Acquired by mining company; fka Anew Medical | |
| AnaBioTec | , | Now Anacura |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Omnia Biologics | , | Website gone Sep 2017 |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| NovaLead Pharma | Pune, India | Small Molecules |
| SulfaGENIX | , | Website gone, Jan 2019 |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| Ergomed | Moscow, Russia | Clinical Research |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| SGC Pharma | , | Website taken over, Nov 2016 |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Remedium Bio | Needham, MA | Gene Therapy |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Cellipse | , | Website taken over May 2020 |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Correlogic | , | Assets bought by Vermillion 2011 |
| MatTek | Ashland, MA | Cell Products, Services |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| SenzaGen | Lund, Sweden | Genomic Assays |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| , | Website taken over Feb 2026 | |
| Revotek | , | Website down May 2023 - Sep 2023 |
| EuroAPI | Paris, France | API Production, CDMO |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Seer | Redwood City, CA | Early Detection |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Indena | Milan, Italy | CDMO |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Medicure | Winnipeg, MB | Small Molecule |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Anvyl | , | Website gone Jan 2021 |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| Axxam | Milan, Italy | Drug discovery services |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Autotelic | , | Gone 2022 |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Avomeen | , | Acquired by Element, Mar 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Cureport | Worcester, MA | Nanomedicines |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| MetaMorphix | , | Changed to Scidera Genomics |
| Cristers | Suresnes, France | Generics |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| , | Liquidated Jun 2025 | |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| , | Website down May 2025 - Sep 2025 | |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| Corza Medical | Boulder, CO | Surgical Devices |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| , | Now PiSA USA | |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| CereSpir | , | No news 2020 - Nov 2024 |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Bach Pharma | , | Shut down late 2023 |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Skylit Medical | , | Renamed Clarify medical |
| CareDx | Brisbane, CA | Diagnostics |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Bioventus | Cordova, TN | Orthobiologics |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| EMD Serono | Boston, MA | Biologics |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Noeledge | , | Shut down Jul 2024 |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Ileo Science | , | Seems gone Mar 2022 |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Iconovo | Lund, Sweden | Inhalation Technology |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Activ Surgical | Boston, MA | Surgical Software |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Aviv Biomedical | , | Shut down 2018 |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| TheoremDx | , | Bankrupt Feb 2020 |
| , | Website down Nov 2025 - Apr 2026 | |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| Shionogi | Florham Park, NJ | Small Molecules |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Aracea Therapeutics | , | No website Aug 2022 |
| EcoSurg | , | Shut Down May 2017 |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Artera | Los Altos, CA | AI Diagnostics |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| Align Technology | Tempe, AZ | Teeth alignment |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| Eos Biosciences | , | Shut down Oct 2020 |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| GeNO | , | Renamed Vero Biotech, 2018 |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| Biotrofix | , | Gone, Dec 2014 |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| Bayer | Bergkamen, Germany | Small Molecules |
| MerciaPharma | , | No updates 2014-2023 |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Ottobock | Duderstadt, Germany | Prosthetics |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| Apicore | Gujarat, India | API Development & Manufacturing |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| , | Shut down Jan 2026 | |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| , | Website down Aug 2025 - Jan 2026 | |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Idience | San Francisco, CA | Cancer Therapies |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Epocal | , | Acquired by Alere, Feb 2013 |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| Transdermal Technologies | , | Website Gone |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| , | Renamed AtaiBeckley | |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Biocorp | Issoire, France | Medical Devices |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| TrialStat Solutions | Montreal, QC | eClinical |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| Palingen | , | Renamed IGM Biosciences |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Erba MDX | , | Website gone Aug 2019 |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Dendritix | , | Renamed Argos Therapeutics |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| mibe Arzneimittel | Brehna, Germany | Generics |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Quest Clinical Research | , | Now part of eStudysite |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| Vernacare | Maple, ON | Surgical Devices |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| VitaCyte | Indianapolis, IN | Collagenase |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| Memento Medicines | , | |
| Theramex | London, UK | Women's Health |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Divergence | , | Bought by Monsanto |
| Altasciences | Cypress, CA | Contract Research |
| Gene Labs | , | Bought by GSk 2008 |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Medicure | Princeton, NJ | Small Molecule |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Novogene | Beijing, China | Genomic Services |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| , | Website down Oct 2025 - Feb 2026 | |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| Avadel Pharmaceuticals | Chesterfield, MO | 505(b)(2) product |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| Anulex Technologies | , | Closed 2014 |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Folia Biotech | , | Website Gone May 2018 |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| Lupin | Somerset, NJ | Generics |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| Biomatters | , | Renamed Geneious |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| VersaPharm | , | |
| BalinBac Therapeutics | , | Gone 2018 |
| Optical Imaging | , | Website taken over, Mar 2019 |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| Texcell | Shanghai, China | Contract Research |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| In-Depth Genomics | , | Shut down Jan 2021 |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Appia Bio | , | Shut down Aug 2025 |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| , | Seems to be News website, Jan 2026 | |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Innexus Biotechnology | , | Gone |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Crown Bioscience | Taicang, China | Drug Development |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| TCG GreenChem | Ewing, NJ | |
| TearScience | , | Acquired by J&J, Nov 2017 |
| Bakersfield, CA | Clinical Trials | |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| R-Pharm | Moscow, Russia | Medical Equipment |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Wetlin Research Associates | , | Centerwatch only |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| BGI | Hong Kong, China | Genetic Testing |
| , | Website down Dec 2025 - Apr 2026 | |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| ARTham Therapeutics | , | Shut Down late 2023 |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Intellirod Spine | , | Sold Assets late 2020 |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| DNA Worldwide | Frome, UK | DNA Testing |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| PreDxion Bio | , | Renamed Refractal |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Rgene | , | Late business filings Aug 2021 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| CMD Bioscience | , | Closed, 2015 |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| NB Therapeutics | , | Gone |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| Theravance Biopharma | South SF, CA | Small Molecules |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| AbbVie | Waco, TX | Contract Manufacturing |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| SWITCH Biotech | , | Gone, 2020 |
| RK Pharma | Pearl River, NJ | Generics |
| GeoVax | Smyrna, GA | Vaccines |
| Partek | , | Acquired by Illumina, May 2024 |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| , | Acquired by Insphero, Nov 2025 | |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Mediatech | , | Now Cellgro |
| Genuiti Therapeutics | , | |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| , | Gone Jan 2025 | |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| 14M Genomics | , | Shut down, Feb 2016 |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| Cellink | Blacksburg, VA | Bioprinting |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| PluriSelect | El Cajon, CA | Cell Separation |
| Glialogix | , | Gone Nov 2017 |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| RepRegen | , | Gone, 2014 |
| VB Spine | Leesburg, VA | Spinal Implants |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| ID Pharma | , | Acquired by I'rom Group |
| Gene Logic | , | Bankrupt |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Perlara PBC | , | Shut down Feb 2019 |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| , | Became part of Accelerator, Dec 2025 | |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Cromos Pharma | Portland, OR | Clinical Research |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Gennova Bio | Pune, India | mRNA vaccine |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| OFD Biopharma | Albany, OR | Lyophilization |
| Verséa Health | Tampa, FL | Diagnostics |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Psomagen | Rockville, MD | Genetic Sequencing |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| InnoCare | Nanjing, China | Cancer Treatments |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Ergomed | Zagreb, Croatia | Clinical Research |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| DiaVax Biosciences | , | Renamed Helocyte |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Xcede Technologies | , | Gone Jun 2020 |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| TreeFrog Therapeutics | Pessac, France | 3D Stem Cell Culture Technology |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Henderson Morley | , | Bankrupt |
| Pharmaron | Cardiff, UK | R&D Services |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| Steba Biotech | , | Renamed ImPact Biotech |
| Gallus | , | Bought by Patheon, Aug 2014 |
| SomaLogic | Boulder, CO | Blood Analysis |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Enterin | , | Website taken over Feb 2025 |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| , | CEO left 2020, still on website Dec 2025 | |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Anergis | , | Liquidating, Jan 2021 |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| , | Website down Aug 2025 - Jan 2026 | |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| PsiThera | Watertown, MA | Oral Small Molecules |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Compugen | San Francisco, CA | Biologics |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| , | No news 2017 - Apr 2026 | |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
 |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| Ottobock | Königsee, Germany | Prosthetics |
| McGee Pharma | , | Merged with Pharmalex |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| MantraPharma | Lévis, QC | Generics |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| VastBiome | , | Renamed PragmaBiome |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Relion | , | Shut down 2015? |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Norgine | Hengoed, UK | Specialty Pharma |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Venclose | , | Acquired by BD, Dec 2021 |
| Axium Pharmaceuticals | , | Dissolved |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| , | Website down, CEO gone Apr 2026 | |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| SomaServe | , | Renamed ViaNautis Bio |
| XaTek | , | No news 2021 - Feb 2025 |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Anacura | Evergem, Belgium | Analytical |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| ICU Medical | San Clemente, CA | Disposable medical products |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| Jetequip | Boucherville, QC | Fluid Handling |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| NeuClone | Sydney, Australia | Biosimilars |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| Hesperos | Orlando, FL | Human-on-a-chip |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| Doloromics | , | Shut down Mar 2025 |
| Tecomet | Kenosha, WI | Implant Components |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| Isolagen | , | Reorganized as Fibrocell Science |
| Life Stem Genetics | , | Basically gone |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| NovoKera | , | Merged into Longevity Biomedical |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| , | Website down Jan 2026 - Mar 2026 | |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Medreich | Bengaluru, India | CDMO |
| Plaxgen | , | Shut Down 2019 |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| Liverpool, UK | Clinical Research | |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| , | Website down Jan 2026 - May 2026 | |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Novaliq | Cambridge, MA | Drug Delivery |
| Validant | , | Renamed Eliquent Life Sciences |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Fortrea | Durham, NC | Clinical Research |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Afferon | , | Gone, no info |
| EVA Pharma | Giza, Egypt | Branded Generics |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| Torpedo Bio | , | |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| Lean Biologix | Norfolk, MA | Consulting |
| Raytone Bio | , | |
| Silere Medical Technology | , | Shut down Dec 2013 |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Apharm | , | Now Biofarma Group |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Peptone | London, UK | Translational Biophysics |
| Applied Therapeutics | New York, NY | Small Molecules |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| Eccogene | Shanghai, China | Small Molecules |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| AngioChem | , | All employees gone, no info, presumed gone |
| Duality Biologics | Shanghai, China | ADCs |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| , | Renamed NeuraNova, Jan 2026 | |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| BioCrea | , | Website Gone, Feb 2018 |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Valsphere | , | Website gone Nov 2019 |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Lung LLC | , | Renamed Lung Biotechnology |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Avioq | Durham, NC | HIV Diagnostics |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| South Coast Clinical Trials | , | |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| AltaRex | , | Gone |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| Immerge BioTherapeutics | , | Founded 2000 |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| , | CA filings late Jun 2024 - Oct 2025 | |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Sonavex | Baltimore, MD | Ultrasound |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| Plexision | Pittsburgh, PA | Diagnostics |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| Catalyst Clinical Research | Raleigh, NC | Clinical research solutions to the global biopharmaceutical industry |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| Safecor Medical | , | Shut down Apr 2021 |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Talis Biomedical | , | |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| Proteorex | , | Gone Nov 2017 |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Conformis | , | |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Grunenthal | Quito, Ecuador | Small molecules |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| Proteins and Peptide Management | , | Now Adocia |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Fabric Genomics | Oakland, CA | Computational genomics |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| ImmuNext | , | Website gone Feb 2025 |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| SNBL | , | Acquired by Altasciences |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| ChemPacific | Baltimore, MD | Chemicals |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Proveri | , | Gone 2016 |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| PlaSalus | , | Amateurish looking |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| , | Pivoted to food, Feb 2026 | |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Cygene Labs | , | Gone |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| Celerion | Montreal, QC | Clinical Research |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| Kumuda | , | Website gone Mar 2023 |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Sonus Pharma | , | Merged with Oncogenex |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Texcell | Gronau, Germany | Contract Research |
| Axikin Pharmaceuticals | , | Closed per Google |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| Antios Therapeutics | , | Shut down Feb 2023 |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| MolPlex | , | Insolvent, 2016 |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| DecImmune Therapeutics | , | Gone 2017 |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| , | Acquired by InformedDNA, Mar 2025 | |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| CSL Behring | Bradley, IL | Biologics |
| PMG Research | , | Now Acellacare |
| BianoGMP | Gera, Germany | Oligonucleotides |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Kivu Bioscience | San Francisco, CA | ADCs |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| Curia | Valladolid, Spain | Contract Development, Manufacturing |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Kiecana Clinical Research | , | Now KCR |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Optime Therapeutics | , | Acquired by Lippomix |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Targanta | , | Bought by The Medicines Company |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Jubilant Cadista | Salisbury, MD | Fully Integrated Contract Research, Generics |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Intellimedix | , | Company founder/employee all moved on |
| Qualicaps | Whitsett, NC | Capsules |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| FusionBio | , | Website down Sep 2025 |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Synthace | London, UK | Development Software |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Sterling | Barrie, ON | Medical Device Contract Manufacturing & Development |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Elite Research Institute | , | Gone, May 2018 |
| Avrygen | , | Website Gone, execs gone |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| GT Apeiron | Shanghai, China | AI Drug Development |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| Proscia | , | |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Pharmathen | Marousi, Greece | Generics |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Isis Biopolymer | , | Website taken over |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Novalar | , | Licensing agreement, essentially gone |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| Parexel | Newton, MA | Clinical Research |
| iThemba Pharmaceuticals | , | No information |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
 |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Sancilio | , | Now Micelle BioPharma |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Ovation.io | Portland, ME | LIMS |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Newormics | , | Renamed vivoVerse, late 2022 |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Syneos Health | Princeton, NJ | Clinical Development |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| , | Website down May 2025 - Dec 2025 | |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| OrphoMed | , | Shut Down 2022 |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| Enci Therapeutics | , | No website, business suspended by NC |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Seraph Biosciences | Detroit, MI | POC Pathogen Detection |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| CereScan Corp | , | Renamed CereHealth |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Repligen | Waltham, MA | Protein Manufacturing |
| |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| MetaStat | , | Website gone May 2019; Shell Company |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| AngioCure | , | Employees all gone, Nov 2017 |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Progyny | New York, NY | IVF products |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| Solvay | , | Bought by Abbott 2010 |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| , | Website down Jan 2026 - May 2026 | |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Znomics | , | Bankrupt, Shell Company Now |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| Inovio Biomedical | , | Seems gone |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| Ergomed | Raleigh, NC | Clinical Research |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| CD Genomics | Shirley, NY | Genomics Services |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Retroject | , | Seems gone |
| CRIO | Boston, MA | eClinical Software |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| White Biotech Solutions | , | Shut Down 2019 |
| Mabqi | Grabels, France | Antibody Discovery |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| , | Renamed ElisiGen, Dec 2025 | |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| Trophea Development | , | Liquidated Dec 2019 |
| AssureRx | , | Renamed Assurex Health |
| CyBio | , | Merged into Jena, Jul 2014 |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| , | Acquired by Canoa, Aug 2019 | |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Santen | Osaka, Japan | Ophthalmics |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| Intercytex | , | Liquidated |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Newcastle, WA | Contract Chemistry Services | |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Ceronco Biosciences | , | Gone 2015? |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Calcionics | , | Shut down 2010 |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| , | Website down Oct 2025 - Feb 2026 | |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| Optimata | , | Shut down May 2019 |
| CureBiotech | , | Presumed gone |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| CoRegen | Aspen, CO | Genetically Engineered T Reg Cells |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| , | Website down Jan 2026 - May 2026 | |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Promethera Biosciences | , | Renamed Callaion |
| HebeCell | Natick, MA | Cell Therapies |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Terapio | , | Website Gone, Sep 2020 |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Venta Medical | , | Gone, Apr 2017 |
| Clontech | , | Now Takara Bio |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| Nuvik Therapeutics | , | No website, very little info |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| TargeGen | , | Bought by Sanofi 2010 |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Kesios Therapeutics | , | Closed down according to investors |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| SineuGene | Beijing, China | Gene Therapy |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Cytomatrix | , | Gone, Jun 2013 |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| , | Website down Jul 2025 - Dec 2025 | |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| GeneAssess | , | Gone |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| CyberHeart | , | Acquired by Varian, May 2019 |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| Clarivate | London, UK | Vascularized organoids |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| AQEMIA | Paris, France | AI Drug Discovery |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Septerna | South SF, CA | GPCR Drug Discovery |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| , | Renamed Racura Oncology, Dec 2025 | |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| Gene Techno Science | , | Renamed Kidswell Bio |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| 10BioSystems | , | Website Gone, Apr 2016 |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Dundee Cell Products | , | Renamed DC Biosciences |
| , | Shut down Sep 2025 | |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Phenomix | , | Shut Down 2011 |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| Eurosequence | , | Website gone Jan 2020 |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| MacroPore | , | Gone |
| Thermo Fisher | Bend, OR | CDMO |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Gene ID inc | , | Website taken over |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| DyNAbind | , | Shut down Apr 2025 |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Stimwave | , | Bankrupt, Oct 2022 |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| MSD | Leopardstown, Ireland | Small Molecules |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| Indago | , | Renamed Lazurite |
| Roche | Welwyn, UK | Small Molecules |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Xhale | , | Acquired by Philips, Aug 2018 |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Guardion Health Sciences | , | Shut down |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| Optovue | , | Renamed Visionix Sep 2021 |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| , | Website down Jul 2025 - Dec 2025 | |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| JAMP Pharma | Boucherville, QC | Generics |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| ViroPharma | , | Bought by Shire Jan 2014 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Abbott | Longford, Ireland | Diagnostics |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| Oscor | , | Acquired by Integer, Dec 2021 |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Viva Biotech | Shanghai , China | Contract Research |
| Acologix | , | Closed Aug 2011 |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| , | Website down Dec 2025 - May 2026 | |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Proimmune | Oxford, UK | Immunology research products |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| EyeCyte | , | Gone 2014 |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Iontas | , | |
| Velos | , | Acquired by WCG, Mar 2018 |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Omnitura | , | Website gone Jan 2022 |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Innovative BioTherapies | , | Gone |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Vectura | , | |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Molecular Throughput | , | Rebranded as mtibio |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| ViThera Pharmaceuticals | , | Gone 2017 |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| BinaryBio | , | Out of business Jul 2015 |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| LemnaGene | , | Acquired by Biolex 2005 |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| , | Website gone Feb 2026 - Apr 2026 | |
| Artificial | Palo Alto, CA | AI Lab Platform |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Cuda Pharmaceuticals | , | Presumed gone |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| OmniGuide | Billerica, MA | Surgical technology |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| , | Website down Jul 2025 - Nov 2025 | |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| Promosome | , | Gone |
| Virax Biolabs | London, UK | Viral test Kits |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Ceptyr | , | Out of business 2012 |
| , | Acquired by Bruker, May 2024, €870M | |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Ansaris | , | Gone |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| Venebio | Glen Allen, VA | Consultants |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| InnoVoyce | Boston, MA | ENT Lasers |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Roche | Schlieren, Switzerland | Small Molecules |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Novacta | , | Website Gone, no info |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| CompleGen | , | Shut down Aug 2021 |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| AM2PAT | , | Trouble with contaminated products, gone |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| Life Analytics Group | , | Gone |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| Calzada | , | Renamed Polynovo |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Transnetyx | Cordova, TN | Automated PCR Services |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Valneva | Livingston, UK | Biologics Manufacturing |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Innomab | , | Gone 2017 |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Nina Biotherapeutics | , | Gone, after 2015 |
| , | No news 2018 - Sep 2025 | |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| , | Shut down Jan 2025 | |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| , | Website down Oct 2025 - Jan 2026 | |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Instapath | Houston , TX | Automated Digital Pathology |
| Evonetix | Cambridge , UK | Desktop Platform for DNA Synthesis |
| Stada | Bad Vilbel, Germany | Generics |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| QL Biopharm | Beijing, China | Biologics |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Salgomed | , | Shut down Apr 2022 |
| TrueBinding | Foster City, CA | Biotherapeutics |
| |
Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| Synomics | , | Now Smithers Pharma Services |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| NeuroVia | , | Shut down 2019 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Calibrant | , | Closed |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| , | Website down Jun 2025 - Dec 2025 | |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| MeDiNova Research | , | Now part of Accelacare |
| Pangaea Pharmaceuticals | , | Became Zycos |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| ImmuneWorks | , | Website gone, Apr 2018 |
| Aranscia | Houston, TX | Diagnostic Software |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| , | Renamed Mobia Medical, Feb 2026 | |
| Kalypsys | , | Gone |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Norgine | Milan, Italy | Specialty Pharma |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Wepredic | Saint Gregorie, France | Cell Lines |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| BioConsulting International | , | Ancient website, presumed defunct |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Velia Therapeutics | , | Shut down Jan 2025 |
| Cdymax | Bangalore, India | APIs |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| ProCrysta Biologix | , | Shut down 2018 |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| CombiGene | , | Stopped research Jan 2025 |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| , | Founder, Principal gone Sep 2024 | |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| Cato Research | , | Renamed CATO-SMS |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| Veravas | Oakdale, MN | Diagnostics |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Niche Generics | Arlesey, UK | Contract Generics |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Sinotherapeutics | Shanghai, China | Generics |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Centinel Spine | West Chester, PA | Spinal Implants |
| , | Acquired by Embecta, Mar 2026 | |
| Cognosetta | , | Gone 2021 |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Mobius Medical | Sydney, Australia | Clinical Research |
 |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| SynapDx | , | Shut down, Mar 2017 |
| Gilead | Oceanside, CA | Small Molecules |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Formulatrix | Bedford, MA | Lab Automation |
| PreventAGE Health Care | , | fka Journey Biosciences |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Cerimon Pharmaceuticals | , | Gone |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| AndroScience | , | Ancient website, no news 2014-2023 |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| Ergomed | Krakow, Poland | Clinical Research |
| NewVac | , | |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| Getinge | La Ciotat, France | Medical Technology |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Avontec | , | Gone |
| OcuDyne | , | AMD Medical Device |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Lumenis | Beijing, China | Energy-based medical treatments |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Asarina Pharma | , | Winding down Jul 2024 |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Protalex | , | Failed 2018, shell |
| Recida Therapeutics | , | |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Genovis | Cambridge, MA | Nanoparticles |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| Ximedica | Providence, RI | Medical Device Services |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Supratek Pharma | , | Website gone Sep 2017 |
| AtCor Medical | , | Now part of CardieX |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| Accelsiors | Budapest, Hungary | Clinical Research |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Entropia Biosciences | , | Shut Down June 2019 |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Ribomic | Tokyo , Japan | Aptamers |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Immunome | Exton, PA | Cancer Immunotherapy |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Hemaquest | , | Gone by 2017, No info |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| Drugabilis | Villejust, France | Druggability Services |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Procognia | , | Website Gone, Layoffs 2014 |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| , | Website down Oct 2025 - Feb 2026 | |
| Santen | Emeryville, CA | Ophthalmics |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| Lusis | Hayward, CA | Diagnostics |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| ImmuRx | , | Gone, not sure what happened |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| Trilations | New York, NY | Strategic Consulting |
| New Brunswick Scientific | , | Merged into Eppendorf |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| , | Website down Oct 2025 - Jan 2026 | |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| Courante Oncology | Excelsior, MN | Clinical Research |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| CPI Global | , | Website gone Jun 2020 |
| , | Website down Jul 2025 - Oct 2025 | |
| Stealth Therapeutics | , | Gone |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Adlyfe | , | Gone, no info |
| Gennova Bio | Pune, India | mRNA vaccine |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Chrysalis | Burlington, MA | GMP Space |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| CenterVue | , | Merged into iCare, Apr 2020 |
| DM Clinical Research | Houston, TX | Clinical Research |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| StemBioSys | San Antonio, TX | Stem Cells |
| Myoposity Therapeutics | , | Gone |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Xcelthera | , | Shut down, Apr 2021 |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| Apnex Medical | , | Shut down, Aug 2013 |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Alltrna | Cambridge, MA | tRNA therapies |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| MabPrex | , | Out of business, 2016 |
| Genomadix | Kanata, ON | Portable PCR |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Corin | Cirencester , UK | Orthopedics |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Faze Medicines | , | Shutting down Nov 2022 |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| Dharma Biomedical | , | Website gone Nov 2022 |
| , | Shut down Jul 2025 | |
| BioPointe Scientific | , | Subsumed into parent |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| BGI | Copenhagen, Denmark | Diagnostics |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Parker BioConsulting | , | Sole employee is a professional board member |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| Targenics | , | No website Mar 2020 |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| British Biotech | , | Merged into Vernalis 2003 |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| , | Website down Sep 2025 - Dec 2025 | |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| , | Liquidating Feb 2025 | |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Locanabio | , | Shutting down late 2023 |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| MetaMol Theranostics | , | Gone |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| Figure8 Surgical | , | Surrendered business in CA |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| , | Renamed LeonaBio, Jan 2026 | |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Fonar | Melville, NY | Upright MRI |
| , | Renamed Singulera, Nov 2025 | |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Phenoquest | , | Website gone, Oct 2015 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| Grifols | Clayton, NC | Biologics |
| Extract Technology | Mauston, WI | Containment Equipment |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Medtronic | Jacksonville, FL | Medical Devices |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| AllerMAbs | , | Website gone Oct 2022 |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Altasciences | Scott Township, PA | Contract Research |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| Develco Pharma | Schopfheim, Germany | Generics |
| Aethox Therapeutics | London, UK | Inhibitors |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| Veeva Systems | Shanghai, China | Life Science Software |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Genera Medix | , | Apparently sold all products |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| Lux Biosciences | , | Gone |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Trillium Diagnostics | , | Closed Jul 2016 |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| imarc | , | Acquired by Avania, Jun 2021 |
| X7 Research | , | Website hijacked Feb 2025 |
| Owkin | New York, NY | AI for Medical Research |
| Core Dynamics | , | Gone |
| CellASIC | , | Bought by Millipore, May 2012 |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| MyoSyntax | , | Gone 2021 |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Catalent | Winchester, KY | Contract Manufacturing |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| ROKIT | Seoul, Korea | Organ Regeneration |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| Huons | Seongnam, Korea | Small Molecules |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| GnuBIO | , | Bought by Bio-rad |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| Masy Systems | , | fka Masy Biosystems |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Recon Therapeutics | , | Shut down Jun 2017 |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| CeQur | Greenville, SC | Insulin pump |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| MEDISPECTRA | , | Gone 2002 |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| CYTOO Cell Architects | , | |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| TME Pharma | Berlin, Germany | L-aptamers |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Hemay Pharmaceutical | Tianjin, China | |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| , | Website taken over, Feb 2026 | |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| Lindus Health | London, UK | CRO |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| LyoGo | , | Website gone, all employees gone |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Xylo | Boulder, CO | Psychedelics |
| , | Website down Jan 2026 - May 2026 | |
| Anfiro | , | Shut down Dec 2019 |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| , | ||
| Boston Scientific | Valencia, CA | Medical Devices |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| Symbollon | , | Gone |
| Cytera CellWorks | , | Renamed Mytos |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| PhotoSonix Medical | , | Now a licensing outift |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| , | Website down Jan 2026 - May 2026 | |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Lab901 | , | Bought by Agilent |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| Niche Generics | Hitchin, UK | Contract Generics |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Sunho Biologics | Nanjing, China | Biologics |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| Atugen | , | Acquired by SR Pharma 2005 |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| GTX Medical | , | Renamed ONWARD |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Tal Medical | , | Gone |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| ImmunoBiochem | , | No news 2018 -2023 |
| Epigenetix | , | No annual report filed 2013-2019 |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Tri-Pac | South Bend, IN | Contract Filling |
| UniteLabs | , | Shut Down |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| , | Website down Aug 2025 - Jan 2026 | |
| Limerick Bio | , | Gone 2011 |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| , | Merged with ABX-CRO | |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| BA Sciences | Salem, NH | Analytical Services |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| GeneProt | , | Shut down Apr 2005 |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| DNAtrix | , | Gone late 2023 |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| Accellix | Jerusalem, Israel | On-demand Assays |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Pierce | , | Part of Thermo Fisher |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| Eco Quest | , | Now Cynata Therapeutics |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| Vie Diagnostics | , | Renamed Phoresa |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Curia | Camarillo, CA | Contract Development, Manufacturing |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Revvity | Waltham, MA | Diagnostics, Services |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| Empatica | Cambridge, MA | Seizure Detection |
| BioDot | Irvine, CA | Equipment |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| ApoImmune | , | Gone 2014 |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| Lacer | Barcelona, Spain | Small Molecules |
| Quanticate | Bangalore, India | Clinical Research |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| TamuroBio | , | Shut Down Jun 2024 |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| Nexus Genomics | , | Gone 2001 |
| Vistin Pharma | Oslo, Norway | Generics |
| , | No news 2020 - Dec 2025 | |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Gameto | New York, NY | Female Fertility Extension |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| , | Acquired by Sun Pharma, May 2025 | |
| Pharmexon | Prague, Czech Republic | Consulting |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| CardioEphEx | , | Shut down Dec 2020 |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Genopis | , | Acquired by Wacker Feb 2021 |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Biopticon | Princeton, NJ | Tumor Imaging |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| Digene | , | Merged with Qiagen |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| LivaNova | London, UK | Nerve stimulation therapy |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Cerebroscience | , | One employee, website gone |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Elanex Pharmaceuticals | , | Gone |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| Heraeus Medical | Dorado, PR | Medical Devices |
| DynoSense | , | Shut down Sep 2022 |
| Bio-Detail | , | Website gone Feb 2023 |
| GEROPHARM | Moscow , Russia | Large drug maker |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| GenoSpace | Boston, MA | Platform for genomic data |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Science 37 | Morrisville, NC | CRO Recruitment |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| CyteGen | , | 2015 founded, website never active |
| Ascenta Therapeutics | , | Gone |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| , | Website down Jul 2025 - Jan 2026 | |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Mitos Pharmaceuticals | , | Website Gone |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| Genetron Health | Beijing, China | Diagnostics |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| Mesoblast | New York , NY | Regenerative Medicine |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Silenseed | , | Renamed Silexion |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| , | Website down Jan 2026 - Mar 2026 | |
| Microislet | , | Bankrupt 2008 |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| Roslin Cells | , | Renamed RoslinCT |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Athens Bioscience | Athens, GA | Purified human proteins |
| , | Part of SBO Hearing, Feb 2026 | |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| Regenicin | , | Residential address, three employees, no money |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Smart Biosciences | , | Renamed sb-Peptide |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Optherion | , | Sold Assets, Still Exists |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Roche | Basel, Switzerland | Diagnostics |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Sonexa Therapeutics | , | Closed 2013 |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Accord Healthcare | Ahmedabad , India | Generics |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| Selten Pharma | , | Gone 2017 |
| NKMax America | , | Renamed NKGEN Biotech |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Viravaxx | , | |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| VGX Pharmaceuticals | , | Merged with Inovio |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Mabcare Therapeutics | , | |
| Alt Bioscience | , | Now PDx Biotech |
| KALA BIO | Arlington, MA | Drug Delivery |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Rx3 | , | Now Trius Therapeutics |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Vyteris | , | Bankrupt 2012 |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| SemBioSys | , | Bankrupt, Jul 2012 |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| Nvelop Therapeutics | , | |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| CATO SMS | , | Renamed Allucent, May 2022 |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Accium BioSciences | , | Shut down Oct 2024 |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| SIMR (Australia) Biotech | Shanghai, China | CNS Small Molecules |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Cellenion | Berlin, Germany | Single Cell Testing |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Tripos | , | Bought by Certara |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| CTC | Uppsala, Sweden | Clinical Site Network |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Prognosys Bioscience | , | 10 years in stealth mode |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Redoxis | Lund, Sweden | Drug development CRO |
| hC Bioscience | , | Shut down Mar 2025 |
| Batu Biologics | , | Gone 2019? |
| Nuvation Bio | New York, NY | Oncology Treatments |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| Novonesis | North Rocks, Australia | Enzymes |
| Biotechnical Services | , | Shut down Apr 2019 |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Okairos | , | Acquired by GSK, May 2013 |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| STARLIMS | Hollywood, FL | LIMS |
| Accellacare | Raleigh, NC | Clinical Research |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| MacuClear | , | Website gone Jan 2019 |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Kendle | , | Acquired by INC Research 2011 |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| VistaMed | , | |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| Cytiva | Freiburg, Germany | Medical Devices |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Jenken Biosciences | , | Shut down by 2014 |
| Enterey | Irvine, CA | Life Science Consulting |
| Medelis | Thompson's Station, TN | Clinical Research |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| Camurus | Lund, Sweden | Specialty medicines |
| GeneVivo | , | Unknown Fate |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| LifeSensors | , | Website hijacked Feb 2025 |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| Texcell | Frederick, MD | Contract Research |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Sanarus | , | Acquired by Hologic, 2020 |
| , | Website under construction, Feb 2024 - Nov 2025 | |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| , | Acquired by Waters, 2023 | |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| iKaryos Diagnostics | , | Gone |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| ProPharma Group | San Diego, CA | Consulting |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| EuBiologics | Seoul, Korea | Vaccines |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| Abcellute | , | Dissolved, Sep 2016 |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| Advangen | , | Acquired by Cellmid, May 2013 |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Corza Medical | Shanghai, China | Surgical Devices |
| , | Website down Dec 2025 - Apr 2026 | |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Nura | , | Acquired by Omeros |
| Silktap | , | Liquid silk. Site gone |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| InnoCare | Beijing, China | Cancer Treatments |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Nano Oncology | , | Gone |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| STX-Med | , | Renamed Cefaly |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Linical | Stuart, FL | Clinical Research |
| , | Website down Dec 2025 - Apr 2026 | |
| Marical | , | Website Gone |
| Angex Pharmaceuticals | , | Gone 2018 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| Resprotect | , | No update since 2012 as of 2020 |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Cambridge Pharma | , | Rolled into parent, SMC |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Orexia | , | Acquired by Centessa |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| , | Renamed Benthic Genomics, Sep 2025 | |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Cytosolix | , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed |
| Saffron Therapeutics | , | Website down Oct 2021 |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| RS Medical | Vancouver, WA | Medical Devices |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Ionpath | , | Shut down Feb 2025 |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Via Pharmaceuticals | , | Shell Company |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Emergo by UL | Austin, TX | Medical device consulting |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| GenomeKey | Bristol, UK | IVD Device |
| RNA Therapeutics | , | No website Mar 2020 |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| NexMed | , | Now Apricus Bio |
| , | Shut down Mar 2026 | |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| South Coast Clinical Trials | , | Website gone |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| Orion Genomics | St. Louis, MO | Biomarkers |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Resilience | Alameda, CA | Biomanufacturing |
| PepLib Biotech | Metuchen, NJ | Peptides |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Aztech Sciences | , | Website gone Jun 2021 |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Nanostream | , | Closed Mar 2008 |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Terumo Medical | Somerset, NJ | Medical Devices |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| In Cell Art | , | Website taken over Feb 2025 |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| |
Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Website hijacked Oct 2025 | |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| Ally Therapeutics | , | Shut down early 2021 |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| AstronauTx | London, UK | Alzheimer's Treatments |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| Ipsen | Dublin, Ireland | Small Molecules |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| Synergx | , | Owned by Morphogenesis |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| GenturaDx | , | Bought by Luminex 2012 |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| , | Stopped work Aug 2025, IP company | |
| , | Acquired by Instem, Jul 2025 | |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Aliquot Solutions | , | Shut down Oct 2024 |
| IQVIA | San Diego, CA | Clinical Research |
| DDL | Edison, NJ | Device Testing |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| Novonesis | Beijing, China | Enzymes |
| Imcyse | , | Liquidating, Jun 2025 |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Pharmaron | Beijing, China | R&D Services |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Bayer | Mexico City, Mexico | Small Molecules |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Biocoat | Horsham, PA | Medical Device Coatings |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| , | Website down Sep 2025 - Dec 2025 | |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Eden Biodesign | , | Bought by Watson |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Catylix | , | Shut down Oct 2021 |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| Createrna Science | Wuhan, China | Small Molecules |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| , | Website down Oct 2025 - Feb 2026 | |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| , | Shut down Oct 2025 | |
| Anesiva | , | Bankrupt 2010 |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| DiaGenic | , | Switched to energy sector |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Spiden | , | Renamed Liom, Jul 2024 |
| Kasocio | , | Liquidated, Dec 2019 |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Ataia Medical | , | Website taken over Jan 2024 |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| PDL BioPharma | , | Shut down early 2021 |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| Madeira Therapeutics | , | Gone. No info |
| Curia | Rozzano, Italy | Contract Development, Manufacturing |
| FHC | Bowdoin, ME | Medical Devices |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| , | ||
| Valor Biotechnology | , | Renamed Roivant |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| , | Website down Nov 2025 - Apr 2026 | |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| EyeTel Imaging | , | Gone Jul 2015 |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Verix Health | , | Renamed Serpex Medical |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| Cytiva | Marlborough, MA | Medical Devices |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| InCytu | , | Website gone Jul 2015 |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Xact Medical | , | Website down Mar 2024 |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Active Implants | , | Renamed NUsurface |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| VaxInnate | , | Dissolved Feb 2017 |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Élancé Therapeutics | , | Bispecific Antibodies |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Tigris Pharmaceuticals | , | Now Kirax |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Journey Colab | , | Shut down Jan 2025 |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| TumorEnd | , | Website gone Feb 2019 |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Hypromatrix | , | Gone 2007 |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| GNA Biosolutions | , | Now part of HP Health |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Claritas Genomics | , | Closed Jan 2018 |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| Sojournix | , | Shut down Jun 2021 |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Omixon | Boston, MA | Next-gen sequencing products |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| , | Website down May 2025 - Dec 2025 | |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Recodagen | , | Gone Jun 2009 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| Medrobotics | , | Bankrupt Jun 2022 |
| NantHealth | El Segundo, CA | Diagnostics |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| |
Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| XenaCare | , | Gone |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| IQVIA | Parsippany, NJ | Clinical Research |
| Lupin | Mumbai, India | Generics |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Xyntek | , | Segment of non-life science business |
| , | Acquired by MasterControl, Mar 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| GT Molecular | Fort Collins, CO | PCR Kits |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Telis Bioscience | , | Renamed Alvea |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| CardioCreate | , | Shut Down Jun 2020 |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Healogix | Doylestown, PA | Consulting |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| , | Website down Oct 2025 - Jan 2026 | |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Strike Bio | , | Assets auction, Aug 2017 |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| Quellthera | , | Subsumed into Liveleaf |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Delta-Vir | , | Website down Mar 2023 |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Telephus Medical | , | Now Telephus Biosciences |
| Mattson Jack | , | Now Kantar Health 2009 |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Profusa | Emeryville, CA | Real-time biosensors |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| , | Acquired by Bruker, Sep 2020 | |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Pharmaron | Coventry, RI | API Manufacturing |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Beta Pharma | Princeton, NJ | Small Molecules |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| Cilag | , | Joined J&J 1959 |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Alcon | Houston, TX | Eye-Care Products |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Onyvax | , | Assets Apparently Acquired |
| Defyrus | , | Website gone Nov 2017 |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Gentel Bio | , | Ceased Operations 2012 |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| InterGenetics | , | Assets auctioned |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| , | Became part of Accelerator, Dec 2025 | |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Corcym | London, UK | Implants, Instruments |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Cardeas Pharma | , | Gone, 2017 |
| Apini Therapeutics | , | |
| Scientia Advisors | , | Website gone Jul 2015 |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Aeres Biomedical | , | Gone Jul 2013 |
| PnuVax | , | No news 2017 - Aug 2024 |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Kegelbell | , | Shut down, Dec 2024 |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| Xenova | , | Acquired by Celtic Pharma |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| Cure Foreward | , | Services suspended, May 2017 |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| Protelica | , | Dissolved, Dec 2006 |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| NextCure | Beltsville, MD | Immune Therapies |
| CertiRx | , | Shut down |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Norganoid | Macclesfield, UK | Organoid Technology |
| preclinics | Parma, Italy | Contract Research |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| Axial Biotech | , | Closed Mar 2013 |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| Minakem | Dunkerque , France | API Manufacturing |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| VAXX | , | Not sure what happened to them |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| IvWatch | Newport News, VA | IV infiltration detection |
| Nexgenia | , | Gone Dec 2019 |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Piramal | Rabale, India | CDMO |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| Getinge | Antalya, Turkey | Medical Technology |
| Biotix | San Diego, CA | Lab Consumables |
| , | Website down May 2025 - Dec 2025 | |
| , | Acquired by eurifins, Sep 2024 | |
| Gene Express Inc | , | bankrupt? |
| SIRGA Advanced Biopharma | , | Appears defunct |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| QuantRx Biomedical | , | Shell company |
| Targinta | Lund, Sweden | Antibodies for Cancer |
| Affinity Bio | , | Renamed MyriO Tx |
| SOLADIS | , | Acquired by Efor, 2021 |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Bridge Laboratories | , | Gone 2013 |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| LeukoSite | , | Acquired by Millennium 1999 |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| , | No news 2020 - Nov 2025 | |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| Merck KGaA | Singapore, Singapore | |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| 89bio | Rehovot, Israel | Liver Treatments |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Heraeus Medical | Changshu, China | Medical Devices |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Persomics | , | Gone 2019 |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Phasiq | , | Website gone Jul 2018 |
| Evestra | San Antonio, TX | Women's Health |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| HackScience | , | Renamed Cytera, Nov 2018 |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| Rubicon Research | Thane , India | Generics |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Surepharm | , | Liquidating, Apr 2025 |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| Certego Therapeutics | , | Seems gone May 2023 |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| , | Crypto Pivot, Nov 2025 | |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| HarkerBIO | , | Shut down Apr 2019 |
| Agenix | , | Gone, Website taken over |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Delpharm | Evreux, France | Contract Manufacturing |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| , | ||
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| , | Renamed Indero | |
| MIFCOR | , | Founders both gone Feb 2021 |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| , | Website down Jan 2026 - May 2026 | |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| GeneDx | Stamford, CT | Genetic Data |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| Incyte | Wilmington, DE | Small Molecules |
| Celerion | West Conshohocken, PA | Clinical Research |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| Phoresa | , | Shut down Mar 2018 |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| , | Website down May 2025 - Oct 2025 | |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| InxMed | Beijing, China | Oncology Treatments |
| Kereos | , | Seems gone |
| Ergomed | London, UK | Clinical Research |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Bayer | Berlin, Germany | Small Molecules |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| Esper Therapeutics | , | Shut down 2016 |
| , | Renamed Entirety Biomedical | |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Dynatherm Medical | , | Shut down 2012 or later |
| MantaBio | Beverly, MA | Real-time PCR System |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Riverain Technologies | Miamisburg, OH | Imaging |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Nephrion | , | Closed 2006? |
| IONETIX | Lansing, MI | Radiopharmaceutical |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Zelos Therapeutics | , | No site |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| yuFlu | , | No website, no info Feb 2021 |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Microsure | Son, Netherlands | Surgical Robots |
| Singulex | , | Shut down Jun 2019 |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| Teva | West Chester, PA | Small Molecules |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Viral Genetics | , | Now VG Life Sciences |
| , | Shut down Oct 2024 | |
| Immunogen (1) | , | Renamed ImmunogenX |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| Eminent Services | Frederick, MD | Drug Services |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| Chromocyte | , | |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| CardioCanary | , | Founders gone. Doubt it's active |
| , | Acquired by Avania, Oct 2024 | |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| MindWalk | Victoria, BC | Custom Antibodies |
| Coley Pharma | , | Acquired by Pfizer |
| SunMed | , | Renamed AirLife |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| Oncofactor | , | Gone 2016 |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| CoAxia | , | Closed down Spring 2013 |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| Primera Biosystems | , | Now PrimeraDx |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Aves Labs | , | Now part of Antibodies Inc |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| NS Pharma | Paramus, NJ | Small Molecule |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Altair Therapeutics | , | Shut down Feb 2011 |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| , | Acquired by Crypto Group, Jan 2025 | |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| SEQENS | Ecully, France | APIs, Ingredients |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| , | Website down Jan 2026 - May 2026 | |
| |
Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| , | Website down Jan 2026 - May 2026 | |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Baccuico | , | Renamed Bactobio |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| Roche | Pleasanton, CA | Diagnostics |
| Minimus Spine | , | Only real employee now full-time at another company |
| Rafagen | , | Website redirecting to Rophibio |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Rezolute | Redwood City, CA | Biologics |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| EVerZom | Paris, France | Exosome Therapeutics |
| Comac Medical | Sofia, Bulgaria | European CRO |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| NeurOptics | Irvine, CA | Pupillometry |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| icometrix | Boston, MA | Imaging AI |
| Ansata Therapeutics | , | Out of business 2007 |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| Oticon | Somerset, NJ | Hearing Aids |
| Multerra Bio | , | Bankrupt May 2021 |
| Axplora | Mourenx, France | API manufacturing |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| , | Winding down, Dec 2025 | |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Biolab Pharma | Mississauga, ON | Small Molecules |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Excaliard | , | Bought by Pfizer 2011 |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| , | Seems inactive Jan 2026 | |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Holloway America | Springfield, MO | Vessels, Tanks |
| nplex biosciences | , | Renamed Nomic Bio |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| 89bio | San Francisco, CA | Liver Treatments |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Oticon | Smørum, Denmark | Hearing Aids |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| Visitube | , | No website Mar 2020 |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Cellworks | South SF, CA | Biosimulations |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Mologen | , | Liquidating, May 2020 |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Phytomedics | , | Can't find info on it |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| , | Gone 2023, website taken over by a designer | |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| Excelimmune | , | Closed Jul 2016 |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Embecta | Parsippany, NJ | Diabetes Care |
| BioArctic | Stockholm, Sweden | CNS treatments |
| AB Science | Paris, France | Small Molecules |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Kylin Therapeutics | , | Sold |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| CMC Biologics | , | Now part of AGC Biologics |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Almac | Craigavon, UK | Pharmaceutical Services |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Nodality | , | Gone |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Anavex Life Sciences | New York, NY | Small Molecules |
| Zai Lab | South SF, CA | Small Molecules |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| , | Website down Jun 2025 - Dec 2025 | |
| Kona Medical | , | Closed, Dec 2016 |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Enlibrium | , | Gone 2018 |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| HeartVista | , | Renamed Vista.ai |
| GeneoDx | , | Website gone Oct 2019 |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| G1 Therapeutics | , | |
| Micropore Technologies | Hyderabad, India | Membrane-Based Process Equipment |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| , | Renamed EarliPoint Health, Oct 2025 | |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Antabio | Labège, France | Antibacterial drugs |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| Coferon | , | Renamed BlinkBio |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| BostonGene | Waltham, MA | Biomedical Software |
| Sequella | , | Ancient website ©2017, last news 2017 |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| Virtici | Seattle, WA | Product / Company Incubator |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| Ascelegen | , | Closed |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Viragen | , | Liquidated Oct 2007 |
| , | Acquired by Olon, 2024 | |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Abbott | Singapore, Singapore | Diagnostics |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Recipharm | Strangnas, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| PolyTherics | , | Joined Antitope to become Abzena |
| , | Website down Dec 2025 - Apr 2026 | |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| LC Technologies | , | Renamed EyeGaze |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| MLAB Biosciences | Needham, MA | Biologics |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Insulete | , | Website gone, presumed inactive |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Epigenos Biosciences | , | |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Proteintech | Manchester, UK | Research Antibodies |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Genocea Biosciences | , | Winding Down May 2022 |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Cogenics | , | Now Beckman Coulter Genomics |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Talecris Biotherapeutics | , | Merged with Grifols |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Core Prognostex | , | Seems inactive |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Sanofi | North York, ON | Biologics, Vaccines |
| Verge Genomics | South SF, CA | Algorithm-based Drug Discovery |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Theranostech | , | Renamed Sandia Biotech |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| , | Website taken over, Jan 2026 | |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| LunaDNA | , | Shutting down Jan 2024 |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| Azano Biotech | , | Now Sandia Biotech |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Getinge | Suzhou, China | Medical Technology |
| Apotech Consulting | London, UK | Life Science Consulting |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| StromaCyte | , | Small time, no info. Defunct |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Eurogentec | Seraing, Belgium | Biologics |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Getinge | Delft, Netherlands | Medical Technology |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| Baxter | Singapore, Singapore | Medication Delivery |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| Intrexon | , | Renamed Precigen |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Staburo | Munich, Germany | Clinical Services |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| , | Small Molecule Therapies | |
| OXON | Madrid, Spain | Real World Evidence |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Bionsight | Chuncheon, Korea | Database For Research |
| AbRegen | , | Website gone, Mar 2019 |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| |
Fontenilles, France | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Nephros | South Orange, NJ | Dialysis Devices |
| Absynth Biologics | , | Website Gone Jan 2019 |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Stada | Vršac, Serbia | Generics |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Metrochem | Hyderabad , India | APIs |
| Urogenix | , | Acquired by Astellas |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| AlcaSynn | , | Renamed ChironWells |
| Viant Medical | Upland, CA | Contract Medical Devices |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Starkey | Eden Prairie, MN | Hearing Aids |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| , | Acquired by Chiesi, Apr 2023 | |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Akttyva Therapeutics | Mansfield, MA | AI-based Drug Discovery |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| , | Website under construction Dec 2024 - May 2026 | |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| QuantumBio | State College, PA | Protein characterization software |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Quartzy | Hayward, CA | Lab Management Software |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| Blansett Pharmacal | , | Gone Jan 2019 |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| NuLife Sciences | , | Shell acquired for a security business |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Obenomics | , | No website Apr 2014 |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Almac | Durham, NC | Pharmaceutical Services |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Santen | Tampere, Finland | Ophthalmics |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Genfit | Cambridge, MA | Drug Discovery |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| , | Website taken over Feb 2026 | |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Integer | Alden, NY | Medical & Surgical Devices |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| XDx | , | Changed name to CareDx |
| CanTx | , | Website gone, Feb 2015 |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| Alms Therapeutics | , | Gone Jul 2022 |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| CanBas | Shizuoka, Japan | Small Molecules |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| BridGE Genomics | , | Gone 2022 |
| Enesi Pharma | , | Renamed aVaxziPen |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Chesapeake Biological Labs | , | Now known as Cangene |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| MSD | Carlow, Ireland | Vaccines |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| , | Website down Oct 2025 - Feb 2026 | |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| Quantificare | Suwanee, GA | Medical Imaging |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Meta-Iq | , | Website gone Jun 2020 |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Stiefel | , | Acquired by GSK |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Xencor | San Diego, CA | Antibody Discovery |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| Chiron | , | Bought by Novartis |
| RadioRx | , | Now EpicentRx |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Topivert | , | Liquidating Jan 2021 |
 |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Tecomet | Wilmington, MA | Implant Components |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| , | No news Sep 2010 - Oct 2025 | |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| DiagnoSearch | Thane, India | Clinical Research |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Baxter | Jayuya, PR | Medication Delivery |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| PACT Pharma | , | Shut down Sep 2023 |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Recopharma | , | Seems gone |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| , | Renamed FocalOne, Feb 2026 | |
| AlloCure | , | Website Gone, Jul 2015 |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| , | Website down Oct 2025 - Feb 2026 | |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| Whole Biome | , | Renamed Pendulum Biosciences |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| , | Acquired by IMA Group, Oct 2025 | |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| NeuroFx | , | Renamed Theratome Bio |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Moon Surgical | Paris, France | Robotic Surgery System |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Accellacare | Wilmington, NC | Clinical Research |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| Flen Pharma | , | Now Flen Health |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| CGT Global | Folsom, CA | Tissue Sourcing |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| NeuroproteXeon | , | Gone 2021 |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Sirius Genomics | , | Gone |
| Androclus Therapeutics | , | Closed, May 2007 |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| Avalyn Pharmaceuticals | Cambridge, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Orochem | Naperville, IL | Reagents, Automation |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| PKPD International | , | Attack website |
| AB Sciex | , | Renamed Sciex |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Furong Biotech | , | |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| Verenium | , | Bought by BASF, Dec 2013 |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| VB Spine | Allendale, NJ | Spinal Implants |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| , | Website down May 2025 - Sep 2025 | |
| Metamark Genetics | , | Shut down 2018 |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Viatris (2) | Hyderabad, India | Small Molecules |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| ChemRegen | , | Seems gone Jan 2022 |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| , | Website down Jul 2025 - Dec 2025 | |
| SARcode | , | Bought by Shire Mar 2013 |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Apic Bio | , | Shut down Jan 2024 |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| , | Website down Jan 2026 - May 2026 | |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| Medochemie | Limassol, Cyprus | Generics |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Vernay | Griffin, GA | Fluid Control Solutions |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Smithers | Akron, OH | Contract Research |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Medallion Therapeutics | , | Shut down 2018 |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Stago | Franconville, France | Diagnostics |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| NextImmune | , | Renamed NXI Therapeutics |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| Procertus | , | Website Gone, Apr 2016 |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Evolve BioSystems | , | Renamed Infinant Health |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| NeuroWave Systems | Beachwood, OH | EEG |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| NTRC | , | Now Oncolines |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| , | Shut down May 2025 | |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Advanced Peptides | , | No business filings since 2011 |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Vericel | Cambridge, MA | Cellular Therapy |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Tensys Medical | , | Website gone Sep 2017 |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| Balboa Biosciences | , | Gone 2010 |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| Novometrics | , | Dissolved Dec 2019 |
| DanPET | , | One guy, Feb 2024 |
| NovaDel Pharma | , | Business dissolved 2014 |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| , | Renamed Grey Matters Health, Apr 2026 | |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| XtalPi | Cambridge, MA | AI Drug Design |
| Gentegra | , | Part of IntegenX |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Zuma Biosciences | , | Company Gone |
| Quanticate | Hitchin, UK | Clinical Research |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| NanoVector | , | Gone 2019 |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| PharmacoFore | , | Now Signature Therapeutics |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| , | Shut down Feb 2026 | |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| Putney | , | Acquired by Dechra, Mar 2016 |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| AC Diagnostics | , | Website from 2004 |
| Capsigen | Vancouver, WA | AAV Vectors |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Novonesis | Paraná, Brazil | Enzymes |
| Weatherden | London, UK | Clinical Consulting |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| Piramal | Grangemouth, UK | CDMO |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| , | Acquired by Immedica, Feb 2025 | |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Librede | , | Acquired by Lygos, Jan 2020 |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Menarini | L'Aquila, Italy | Small Molecules |
| Evogene | Rehovot, Israel | Computational Biology |
| CrelioHealth | Columbia, MD | LIMS |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| May Health | Paris, France | Ovulation Restoration Therapy |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| Qynapse | Paris, France | Imaging Analysis |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Ectycell | , | Part of Cellectis |
| , | ||
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| iBridge Medical | , | Website gone Jan 2020 |
| Pangenetics | , | Bought by Abbott |
| , | Merged with Nova Biomedical | |
| Osteologix | , | Liquidated, Sep 2015 |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| Altos Therapeutics | , | Gone Jun 2019 |
| BioParadox | , | Shut down Dec 2017 |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Elona Pharmaceuticals | , | Gone |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Curium | , | Dissolved, Mar 2015 |
| EmerVax | , | Renamed Circurna |
| Diverse Genomics | , | Website gone Jul 2020 |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| , | Website taken over, Nov 2025 | |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
 |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Statera Therapeutics | , | Shut down Jan 2022 |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| , | Acquired by Tecan, Aug 2021 | |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Redpoint Research | , | Gone 2019 |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| Altasciences | Auxvasse, MO | Contract Research |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| , | Website down Nov 2025 - Apr 2026 | |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| TTP Labtech | , | Renamed SPT Labtech |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| X-Rx | , | Shut down Jun 2020 |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Anoixis | Natick, MA | Pharmacometric Services |
| Ergomed | Geneva, Switzerland | Clinical Research |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| UMN Pharma | , | Liquidating Apr 2025 |
| Allux Medical | , | Shut down, Feb 2009 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Bioptimus | Paris, France | AI Drug Discovery |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| , | Website down Jul 2025 - Jan 2026 | |
| Scholar Rock | Cambridge, MA | Biologics |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| , | Renamed Solario Bio | |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Etubics | , | Rolled into ImmunityBio |
| Kuroki Consulting | , | Shut down 2020 |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| Osteolab | , | Spam site |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| Formation Biologics | , | Rebranded as Forbius |
| Accutome | , | Now part of Keeler |
| ACROBiosystems | Basel, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| CompanyLogo | City, State | Business |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| Idience | Seoul, Korea | Cancer Therapies |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| Ecopharm | , | Website down Feb 2021 |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Agendia | Irvine, CA | Breast Cancer Assay |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Savant HWP | , | Gone 2019 |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| , | Renamed Proxoma, Jan 2026 | |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| EPISONA | , | Gone Nov 2018 |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| RheoSense | San Ramon, CA | Viscometers |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Santen | Osaka, Japan | Ophthalmics |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| Silence Therapeutics | London, UK | RNAi |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Bracco | Milan, Italy | Imaging |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| OverT Bio | New York, NY | Cell Therapy |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Trigemina | , | Shut down Aug 2020 |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Lexogen | Vienna, Austria | RNA kits |
| GIVAX | Boston, MA | GI Vaccines |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| Pace | San German, PR | Analytical Testing, CDMO |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Medpace | Cincinnati, OH | Clinical Research |
| Daré Bioscience | San Diego, CA | Women's Health |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| , | Pivoted to blockchain, Sep 2025 | |
| Astrum | Paris, France | Clinical Development CRO |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| Cell Matrix | , | Acquired by Cancervax |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| CanSino Biologics | Tianjin, China | Vaccines |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| Ignis Therapeutics | Shanghai, China | |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| , | Website down Jul 2025 - Dec 2025 | |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| ARCBio | , | Shut down 2014 |
| EpitoGenesis | , | Gone 2017 |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| , | Website gone Feb 2026 | |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| , | Website taken over May 2026 | |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Noscira | , | Liquidated |
| AAVLife | , | Renamed Annapurna |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| Byonoy | Hamburg, Germany | Microplate Readers |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| Stromedix | , | Bought by Biogen Idec 2012 |
| Trinity Drug Partners | , | Gone |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| MaxThera | , | Shut Down Dec 2011 |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Targovax | , | Renamed Circio, Apr 2023 |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| Chrysalis | Morrisville, NC | GMP Space |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| Automata | London, UK | Lab workflow automation platform |
| , | Website down May 2025 - Dec 2025 | |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Zila | , | Bought by Tolmar, Jul 2009 |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Mindshare Medical | , | Renamed RevealDx |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| , | Shut down Nov 2025 | |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Genemo | , | Seems inactive, Jul 2024 |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| SRI International | Menlo Park, CA | Independent Research |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| Tarsa Therapeutics | , | Product rights acquired |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| inDNA Research Labs | , | Shut down 2015 |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Singular Genomics | San Diego, CA | Genomics |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| DxNow | , | Renamed ZyMot fertility |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| Almirall | Barcelona, Spain | Small Molecules |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Large Scale Biology | , | Shut Down |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| , | No news 2017 - Apr 2026 | |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| Amp Orthopedics | , | Shut down, 2012 |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Hydra Biosciences | , | Website gone Mar 2019 |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Genoma | , | Website gone May 2021 |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| , | Subsumed into Synoptics | |
| SL Pharma Labs | , | Website gone May 2018 |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| Gene Sciences | , | Shut Down Jul 2019 |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Suir Pharma | , | Bankrupt, May 2016 |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| , | Main person has four other jobs, Dec 2025 | |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Vadovations | , | No info. 2012 SBIR grant |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| , | No news 2020 - Apr 2026 | |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| SR Pharma | , | Now Silence Therapeutics |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| Rezolute | Bend, OR | Biologics |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Streck | La Vista, NE | QC & Diagnostic Products |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Applied Integrin Sciences | , | Gone |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Revance | Nashville, TN | Movement Disorder Treatment |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| KVK Tech | Newtown, PA | Generics |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| Acculysis | , | Website gone, sole employee with Agilent now |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Alvotech | Zurich, Switzerland | Biosimilars |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| Advanced Vision Science | , | |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| InvivoGen | San Diego, CA | Life Science Reagents |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| Piramal | Lexington, KY | CDMO |
| Central Pharma | Bedford, UK | Filling, Packaging |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| PLC Medical Systems | , | Renamed RenalGuard |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Zai Lab | Cambridge, MA | Small Molecules |
| NanoTess | Calgary, AB | Biocatalysts |
| SpinalMotion | , | Website gone, 11-30-14 |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| DMD Therapeutics | , | Gone Nov 2018 |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| BioXpert | , | Website gone Mar 2017, employees gone |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| Stemetix | , | Shut down Apr 2021 |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Synthon | , | |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| , | Renamed Athens Bioscience, Mar 2026 | |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| Celsense | , | Shut down Dec 2021 |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Belyntic | Berlin, Germany | Immunotherapies |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| Simbex | Lebanon, NH | Biomechanical devices |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| , | Merged with DefiniGEN to become pixl.bio | |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| InVasc Therapeutics | , | Shut down 2012 |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| , | Acquired by Galecto, Nov 2025 | |
| Quentis Therapeutics | , | Shut down late 2020 |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| Bioquanta | , | Gone 2013 |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| CLCbio | , | Acquired by Qiagen, 2013 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| Geneffects | , | Shut down Feb 2020 |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| Anthra Pharmaceutical | , | Gone |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| Entelos | , | Bankrupt |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| Meristem Therapeutics | , | Defunct |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| , | Acquired by Eclipsebio, Jan 2026 | |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| Cougar Biotechnology | , | Bought by J&J |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Purely Proteins | , | All employees gone, no info |
| Texcell | Evry, France | Contract Research |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| NTC | Milan, Italy | Generics |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Pneumolabs | , | Dissolved Sep 2018 |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Parexel | Harrow, UK | Clinical Research |
| FemtoVox | , | |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Covalent Bioscience | , | Shut down, 2025? |
| Circadiance | Export, PA | CPAP Mask |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Acquired by Healx, Sep 2025 | |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Genex Pharma | Mumbai , India | Generics |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Carolus Therapeutics | , | Business revoked in CA |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Celerion | Vienna, Austria | Clinical Research |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| , | Website down Sep 2025 - Feb 2026 | |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Cytoskeleton | Denver, CO | Research Products |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| VytronUS | , | Shut down Mar 2020 |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Niche Generics | Dublin, Ireland | Contract Generics |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Agile EndoSurgery | , | Gone |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Glenveigh Medical | , | Website down Sep 2024 |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| Acrongenomics | , | No info since 2013, seems gone |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| 3DBiopsy | , | Renamed Triopsy |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| Mousera | , | Renamed Vium |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| Epigene Labs | Paris, France | Data Integration Platform |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Pharmos | , | Gone |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| |
Conshohocken, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Website down Jun 2025 - Dec 2025 | |
| Medica | , | Gone before 2019 |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| , | Website down Oct 2025 - Jan 2026 | |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Selventa | , | Closed 2016 |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Acumed | Hillsboro, OR | Medical Implants |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Novocell | , | Renamed Viacyte |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| Amrita Therapeutics | , | Seems gone |
| Synosia Therapeutics | , | Acquired by Biotie |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| OvaGene Oncology | , | Gone Feb 2020 |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| Acumed | Beijing, China | Medical Implants |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| , | Website down Jun 2025 - Dec 2025 | |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| Collgard Biopharmaceuticals | , | Gone |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Baxter | Deerfield, IL | Medication Delivery |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| , | No news Jan 2021 - Jan 2026 | |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| Semaphore Solutions | Victoria, BC | Lab Software |
| Tolmar | Fort Collins, CO | Small Molecules |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Vivid Genomics | , | Shut down Sep 2023 |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Stellartech Research | Milpitas, CA | Electronic device development |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| Proteonomix | , | Shell Company |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| Mojave Therapeutics | , | Gone |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| CohBar | , | Shut down, late 2023 |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| , | Shut down Mar 2026 | |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Heidelberg, Germany | Scalable Protein Production | |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| , | Renamed MindWalk, Sep 2025 | |
| Pharmanovia | London, UK | Acquisition of Drugs |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| , | Website down Nov 2025 - Apr 2026 | |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| , | Website down Nov 2025 - Dec 2025 | |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| seqWell | Beverly, MA | Sequencing Service |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| TamRx | , | Website taken over Aug 2020 |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| SironRx | , | Website gone Jul 2015 |
| Doylestown, PA | RTSM Platform | |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| MURO PHARM | , | Dissolved, May 2007 |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| , | Website taken over Feb 2026 | |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| Mankind Pharma | New Delhi, India | OTC? |
| OP2 Drugs | , | Website gone Jan 2020 |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| PhoreMost | Cambridge, UK | Biologics |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| DKP Genomics | , | Dissolved Jul 2025 |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Triage Wireless | , | Now named Sotera Wireless |
| Sinobioway | , | |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Avexa | , | Renamed Novita Healthcare |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| KynderMed | , | Renamed Prena |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Norgine | Vienna, Austria | Specialty Pharma |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Galileo Research | , | No news since 2012, presumed gone |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Accellacare | Bristol, TN | Clinical Research |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Website down Jul 2025 - Dec 2025 | |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Avail Medsystems | , | Tech sold Mar 2024 |
| Revolution Biomanufacturing | Canton, MA | mRNA, lipid nanoparticle CDMO |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Able Labs | , | big FDA trouble, gone |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| EpicGenetics | , | Seems gone Jan 2024 |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Genemod | Edmonds, WA | Lab management software |
| NemaPharm | , | Defunct? |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Gangagen | Bangalore , India | Ectolysins |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Genomica | , | Shut down Sep 2022 |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Bioclinica | , | Merged with ERT, 2021 |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Allenex | , | Bought by CareDx, Apri 2016 |
| Exodon | , | Website taken over, Jul 2014 |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| , | No news 2015 - Jan 2026 | |
| ASIT Biotech | , | Renamed DMS Imaging |
| Qlucore | Lund, Sweden | Visualization Software |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| GenoMatix | , | Acquired by Intrexon |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| , | Website down Oct 2025 - Feb 2026 | |
| , | Website down Aug 2025 - Jan 2026 | |
| DiagnoCure | , | Liquidated, Apr 2016 |
| Medtronic | Galway, Ireland | Medical Devices |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| BrainCells | , | Website gone Feb 2014 |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Roche | Burgess Hill, UK | Diagnostics |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Integer | Trenton, GA | Medical & Surgical Devices |
| CureGene | Shanghai, China | |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Calixar | Lyon, France | Membrane Proteins |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Aureon Biosciences | , | Insolvency Proceedings |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| GemacBio | , | Renamed PolyNeuroS |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Niveus Medical | , | Closed Dec 2017 |
| Pfizer | McPherson, KS | Sterile Injectables |
| Elix | Tokyo, Japan | AI Drug Discovery |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| APCRA | , | Shut down 2020 |
| Halo Genomics | , | Bought by Agilent |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Arstasis | , | Appears Gone Sep 2017 |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Securecell | Urdorf, Switzerland | Lab automation |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Pharos iBT | , | aka Pharos iBio |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Annova Chem | , | Gone, 2017 |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| Abbott | Sylmar, CA | Device Manufacturing |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Epigenesis Pharmaceuticals | , | Gone |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| CoreBiome | , | Merged into Diversigen |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Salvat | Miami, FL | Small Molecules |
| Parion Sciences | Durham, NC | Mucosal Targets |
| , | Website down Jun 2025 - Dec 2025 | |
| ClinArt | , | Now ClinArt MENA |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Trilations | Tokyo, Japan | Strategic Consulting |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Avance Clinical | Firle, Australia | Clinical Research |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| , | Website down Aug 2025 - Jan 2026 | |
| , | Website down Jun 2025 - Dec 2025 | |
| Sinovac Biotech | Beijing, China | Vaccines |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Sepiatec | Berlin, Germany | Separation Systems |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Stago | Asnières sur Seine, France | Diagnostics |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Opis Research | Desio, Italy | Clinical Research |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| ATON | Shanghai, China | CDMO |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Purinomia Biotech | , | |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Neuromatters | , | Shut down Dec 2019 |
| TRIA Bioscience | , | Shut down Aug 2021 |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Solace Pharmaceuticals | , | Out of business 2011 |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| AbX Biologics | , | Renamed Abveris |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Tecomet | Wilmington, MA | Implant Components |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| NinePoint Medical | , | Seems gone Sep 2020 |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Abpro | Woburn, MA | Antibodies |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Medarex | , | Bought by BMS 2009 |
| APIE Therapeutics | , | Gone Jun 2025 |
| Pion | Billerica, MA | Dissolution Data |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| DNAe | London, UK | Next-gen Sequencing |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Tides Medical | Lafayette, LA | Biologics |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Avatar Medical | Paris, France | Surgical Visualization |
| Instil Bio | Dallas, TX | Cell Therapy |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Endotis Pharma | , | Founded in 2003. No info |
| Stago | Maastricht, Netherlands | Diagnostics |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| ABD Bioquest | , | Renamed AAT Bioquest |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Stago | Tianjin, China | Diagnostics |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Solano Pharmaceuticals | , | Website gone |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| , | Website down Jul 2025 - Dec 2025 | |
| Iproteos | , | Products now with Accure Therapeutics |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Mithridion | , | Website Gone, Company appears to be as well |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Vanadis Laboratories | , | Gone 2018 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Translational Bioscience | , | |
| PPD | Middleton, WI | Contract R & D, Consulting |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| bioMerieux | Durham, NC | Diagnostics |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Lombard Medical | Didcot, UK | Medical Devices |
| Novotech | Shanghai, China | Clinical Research |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Celerion | Zurich, Switzerland | Clinical Research |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| Ikano Therapeutics | , | Gone |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Norton Scientific | , | Website Gone, Oct 2014 |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Mentrik Biotech | , | Gone |
| Voitheia Bioscience | , | |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| Pharmatrope | , | Absurd website 2020-2023 |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| , | No news 2019 - Sep 2025 | |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Cellevolve Bio | , | Shut down Aug 2023 |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| Zambon | Bresso, Italy | Small Molecules |
| Sampled | Motherwell, UK | Biostorage |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| , | Website taken over, Jan 2026 | |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Allez Health | Carlsbad, CA | Biosensors |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Amphora Medical | , | Shut down May 2019 |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Advena | Bromsgrove, UK | Medical Device Regulatory Consulting |
| KXT bio | , | Shut down 2019 |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| Avadel Pharmaceuticals | Dublin, Ireland | 505(b)(2) product |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Patrin Pharma | Skokie, IL | Generics |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| Profluent | Emeryville, CA | AI Protein Creation |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Veeva Systems | Radnor, PA | Life Science Software |
| Fairway Medical Technologies | , | Website gone |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Summation Bio | , | Shut down May 2023 |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| 1859, Inc. | , | Shut down Jul 2023 |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| Cytoplex Biosciences | , | Gone |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Lumanity | London, UK | Consulting |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Ottobock | Vienna, Austria | Prosthetics |
| Vaxart | South SF, CA | Oral Vaccines |
| Epiomed Therapeutics | , | Gone |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Seeker Biologics | , | Shut down May 2023 |
| , | Reportedly Closed Mar 2026 | |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| Remora Therapeutics | , | Shut down 2021 |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| , | Now PamDx, May 2026 | |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| Gentell | Yardley, PA | Wound Care |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| , | Liquidated 2024 | |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| , | Renamed Edding, Feb 2026 | |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| , | Shut Down Dec 2024 | |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| Five Star Products | , | Liquidated |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Immagene | , | Renamed Flindr Therapeutics |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Beta-Pro | , | Now Triangle Research Labs |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Jet Life Sciences | Hyderabad, India | APIs |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| TR Biosurgical | , | Website Taken Over |
| Sygene Technologies | , | Website gone Nov 2018 |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Stago | Gennevilliers, France | Diagnostics |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| YishengBio | , | Now YS Biopharma |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Apotex | Toronto, ON | Small Molecule Generics |
| Global BioDevelopment | , | Website gone |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| , | Part of Greenpharma | |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| , | Acquired by BICO, Aug 2021, $15M | |
| Novita Healthcare | , | Renamed TALi Digital |
| MicroPort | Shanghai, China | Medical Devices |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| TriVirix | , | Now Nortech Life Sciences |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Omeros | Seattle, WA | Small Molecules |
| , | Acquired by Stryker, Sep 2024 | |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| StemPar Sciences | , | Website disappeared, no news |
| , | Acquired, now a copper & silver explorer in Morocco | |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Sysmex | Tokyo, Japan | Diagnostics |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Theragenics | Buford, GA | Medical Devices |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| Patronus Biotech | Singapore, | |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Sophiris Bio | , | Shut down May 2020 |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| , | Website down Aug 2025 - Jan 2026 | |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| Pharos Dx | , | Gone |
| ions.bio | Planegg, Germany | Biomarkers |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| Biolab Pharma | São Paulo, Brazil | Small Molecules |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| Vanquish Oncology | , | No news 2015-2021 |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Alaeras | , | Dissolved Jan 2014 |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Intact Genomics | St. Louis, MO | PCR kits |
| XellSmart | Shanghai, China | Cell Therapy |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Aegea Biotechnologies | , | |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| EMKinetics | , | Seems inactive Feb 2021 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Almac | Souderton, PA | Pharmaceutical Services |
| Thyritope Biosciences | , | Closed Oct 2016 |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Harmony Labs | , | Now Ei |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Soletics | , | Website gone Jun 2021 |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Synergistix | Sunrise, FL | CRM software |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| Mabimmune | , | Merged with Neurimmune |
| , | Renamed Aurevia | |
| DNALite Therapeutics | , | Renamed Particella |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| , | Website down Sep 2025 - Dec 2025 | |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Enovalife | Paris, France | Biometrics and medical writing services |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| Formex | , | Merged into BioDuro, Nov 2015 |
| , | Renamed Fareon, Feb 2025 | |
| NovoLipid | , | Website Gone |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Altheos | , | Closed |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| , | Acquired by Hologic, Jan 2025, $350M | |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| NX Development | Lexington, KY | Brain Imaging |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Bioventus | Durham, NC | Orthobiologics |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| 1CellBio | , | Gone Jun 2019 |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| Rinat | , | Bought by Pfizer 2006 |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Diassess | , | Renamed Lucira Health |
| NeuroVista | , | Website Gone, President has new job |
| Stat One | Morrisvile, NC | eClinical |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| EndoLogic | , | Seems inactive, Aug 2023 |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Genexa | , | Shut down before Nov 2023 |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| , | Subsumed into Synoptics | |
| NovoMedix | San Diego, CA | Small molecules |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Endomag | Cambridge, UK | Biopsy Tracer |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| NsGene | , | Website gone |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Reading, UK | Analytical Services | |
| , | Website down Apr 2026, seems bankrupt | |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| CTK Biotech | Poway, CA | Diagnostics |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| , | Acquired by Millipore, Dec 2010 | |
| , | Website down Dec 2025 - Feb 2026 | |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| Nya Cell Therapeutics | , | No info |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| Scynexis | Jersey City, NJ | Small Molecules |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Tangent Medical Systems | , | Closed |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Adrenergics | , | Gone Sep 2017 |
| ProPharma Group | Fort Washington, PA | Consulting |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Genstruct | , | Now Selventa |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| NEXGEL | Langhorne, PA | Hydrogels |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| Alderon Biosciences | , | Presumed gone |
| Avivo BioOptics | , | Website down Dec 2022 |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Amivas | Waterford, Ireland | Antimalarial |
| Parexel | Durham, NC | Clinical Research |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| , | No news Jun 2021 - Jan 2026 | |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| Medtronic | Memphis, TN | Medical Devices |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Spyryx Biosciences | , | Shut down 2019 |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Tecnimede | Lisbon, Portugal | Generics |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| BZL Biologics | , | Gone 2003 |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Mardil Medical | , | Website gone Feb 2021 |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Alibion | , | Website down May 2021 - Sep 2021 |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Neuron23 | South SF, CA | AI-drug discovery |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Wokingham, UK | Analytical Services | |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| Avecris | Singapore, Singapore | Gene Delivery |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| EndoInSight | , | Website taken over Sep 2021 |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| United Immunoassay | , | Business revoked Jan 2022 |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| Outset Medical | San Jose, CA | Dialysis Device |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| Afaxys | Charleston, SC | Women's Health |
| , | Website down Dec 2025 - Apr 2026 | |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| AblaCor | , | Shut down May 2019 |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| Diamed | , | Bought by Bio-rad |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Cambrian Genomics | , | Shut down Dec 2017 |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| Curia | San Cristóbal, Spain | Contract Development, Manufacturing |
| VentriFlo | Pelham, NH | Blood Pumping System |
| Adela | Toronto, ON | Liquid Biopsy |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| IGF Oncology | , | Shut down 2022 |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| , | Website down Dec 2025 - Feb 2026 | |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| BioTheryX | San Diego, CA | Small Molecules |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Predicine | Hayward, CA | Liquid Biopsy |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| , | Acquired by Inizio, Dec 2025 | |
| Orchestra BioMed | New Hope, PA | Medical devices |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| DDi | Singapore, Singapore | Clinical Software |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| On-Q-Ity | , | Closed 2013 |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| Curl Bio | , | Shut down Feb 2020 |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| , | Shut down Aug 2025 | |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Indocruit | , | Gone |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Root Lines Technology | , | Renamed Samabriva |
| Personalis | Fremont, CA | Genome Services |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| AdipoGenix | , | Gone Jun 2012 |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| , | Acquired by IQVIA | |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| Coating Place | Verona, WI | Drug Delivery Services |
| Biowest Therapeutics | , | Website Gone |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| , | Website down Jul 2025 - Jan 2026 | |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| Pentapharm | Basel, Switzerland | APIs |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| , | Renamed Algernon Health, Oct 2025 | |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Algenix | , | MN Business revoked, Mar 2004 |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| Esculon | , | Seems defunct, employees gone |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| , | being Acquired by Chugai, Oct 2025 | |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| JK Biopharma Solutions | , | Founder gone |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| Ergomed | Mumbai, India | Clinical Research |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| , | ||
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| Heritage Pharmaceuticals | , | Part of Emcure |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| , | Acquired by Certara, Oct 2024 | |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Biomoles | , | Closed Sep 2017 |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Imstem Biotechnology | , | Website gone May 2021 |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| ApcinteX | , | Centessa Company |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Curia | Springfield, MO | Contract Development, Manufacturing |
| Formycon | Martinsried, Germany | Biosimilars |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Oncodesign Services | Dijon, France | Preclinical services |
| , | Website down Dec 2025 - Apr 2026 | |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| Acrux | West Melbourne, Australia | Drug Delivery |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| Synostics | , | Gone 2014 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Enzo Biochem | , | |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Medice | Iserlohn, Germany | Small Molecules |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Leading Pharma | Fairfield, NJ | Generics |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| Aspreva | , | Acquired by Vifor Pharma |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| Inflammix | , | Renamed AnchorBio Solutions |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Apotex | Toronto, ON | Small Molecule Generics |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| , | Shut down Jan 2025 | |
| , | No news 2022 - Mar 2026 | |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| EndoStim | , | Shut down Jan 2020 |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| NascaCell | , | German Aptamer company, not sure of fate |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Celregen | Hangzhou, China | iPSC |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| Molsid | Lyon, France | Fluorogenic Probes |
| MicroPort | Saluggia, Italy | Medical Devices |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Nigra | , | Acquired by Vernalis |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| Abbott | Alameda, CA | Diabetes Care |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Cardima | , | Bankrupt Dec 2010 |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| MSD | Ballydine, Ireland | Small Molecules |
| Avexxin | , | Rebranded as Coegin Pharma |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| SteriTech | Surrey, UK | Process Equipment |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Denizen Biologics | , | Shut down Mar 2023 |
| Spirometrix | , | Renamed Spirosure |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| PNP Therapeutics | Birmingham, AL | Outlicensed sole product Sep 2021 |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Piramal | Ahmedabad, India | CDMO |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| BBOT | South SF, CA | RAS-targeted small molecules |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Dorphan | , | Shut down so owner could spend more time skiing |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Adepthera | , | Shut down 2014 |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Actavalon | , | Shut down Dec 2020 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| EmpathBio | , | |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| PRA International | , | Now PRA Health Sciences |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| |
Macungie, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Accellacare | Ames, IA | Clinical Research |
| RegeneMed | , | No longer active in CA as of 2014 |
| Therabest | Seoul, Korea | iPSC |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Angel Biotechnology | , | Bankrupt, 2013 |
| , | Website down Aug 2025 - Jan 2026 | |
| Bluestar Genomics | , | Renamed ClearNote Health |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| Koelis | Meylan, France | Prostate Biopsy System |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| , | Winding down Apr 2026 | |
| Delpharm | Lille, France | Contract Manufacturing |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| , | Website down Jul 2025 - Dec 2025 | |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| ActoBio Therapeutics | , | Brought into Precigen |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Syncro Medical | Langhorne, PA | Software development |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| Revvity | Boston, MA | Diagnostics, Services |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| Roche | Laval, QC | Diagnostics |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| Excelya | Boulogne, France | Clinical Research |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| FluoroPharma | , | Shell Company |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| Molecular Loop | Woburn, MA | NGS Technology |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Abbott | Princeton, NJ | Diagnostics |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Cytel | Pune, India | Clinical software, statistical services |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Obecure | , | Inactive, no info |
| Genetic Technologies Group | , | Renamed geneType |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Hunterian Medicine | Cambridge, MA | CRISPR-based drug discovery |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| Metenova | ZZ, Sweden | Mixers |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Flow Eighteen38 | , | |
| Verasonics | Kirkland, WA | Research Ultrasound |
| MicroStem | , | Gone Jun 2017 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| , | Website down Nov 2025 - Feb 2026 | |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| 3D Biomatrix | , | Closed down |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| |
Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| Ribocept | , | Defunct |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| Clina Research | , | Website gone Jul 2023 |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| G6 Spine | , | Gone 2017 |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| , | No news 2021 - Jan 2026 | |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| Originus | , | Gone |
| , | Website taken over May 2026 | |
| Chrono Therapeutics | , | Shut Down 2019 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| WideCELLS | , | Shut down Nov 2019 |
| Kurin | San Diego, CA | Blood Collection Technology |
| Assurance Scientific Laboratories | Birmingham, AL | Molecular Technologies |
| Signalife | , | Renamed Heart Tronics |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| Centricity Research | Toronto, ON | Clinical Research |
| Pharminox | , | Website gone, Aug 2017 |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| , | Liquidating Jan 2026 | |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Envision Genomics | , | Website gone Nov 2019 |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| RelonChem | Cheshire, UK | Generics |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| Akrivis Technologies | , | Gone Jun 2021 |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Rad AI | San Francisco, CA | Radiology Software |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| Celemics | , | Gone Jul 2018 |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Soluble Systems | , | Renamed Solsys Medical |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Velcura Therapeutics | , | Website Gone |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| Pevion Biotech | , | Gone, 2-19-14 |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Brightflow Medical | Paris, France | Heart Failure Device |
| , | No news 2021 - Sep 2025 | |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Akceli | , | Shut down, Sep 2004 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| DiObex | , | Shut Down 2009 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Kelliop | Newark, CA | Diagnostic Reader |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| MYcroarray | , | Renamed Arbor Biosciences |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Elegen | San Carlos, CA | DNA writing |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| Mednoxa | , | Website gone Jan 2020 |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| GenEscence | , | Gone Jul 2013 |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| , | Renamed Torpedo Therapeutics | |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Actis Biologics | , | Gone |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| SaluMedica | , | Website Gone Jul 2015 |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| Medtronic | North Haven, CT | Medical Devices |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| TaiwanBio | , | Website gone Oct 2021 |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| PredxBio | Pittsburgh, PA | Image Analysis |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Knopp Biosciences | , | |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| MDQuest | , | Website Down Feb 2025 |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Pharmaron | Louisville, KY | R&D Services |
| PTM BioLabs | , | Renamed PTM BIO |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| bioMerieux | Lombard, IL | Diagnostics |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| RxGen | , | Renamed Virscio, Jan 2020 |
| BioMS Medical | , | Gone? |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| , | Renamed Until Labs, Oct 2025 | |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Novotech | Melbourne, Australia | Clinical Research |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| ZyGEM | , | Renamed MicroGEM |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Altus Biologics | , | Vertex Subsidiary |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| BiVACOR | Houston, TX | Heart replacement |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| Altiris Therapeutics | , | Presumed Gone |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Station X | , | Website Gone Mar 2018 |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| DDL | Eden Prairie, MN | Device Testing |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| Plexanome | , | Gone 2018 |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Genomic Solutions | , | Acquired by Digilab |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Athlon Pharma | , | No news since 2006 lawsuit |
| , | Crypto Pivot, Oct 2025 | |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Cell Biosciences | , | Now ProteinSimple |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| Grunenthal | Aachen, Germany | Small molecules |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Dexcom | San Diego, CA | Glucose Monitors |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Aliri | Loos, France | Contract Mass Spec |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| M2 Medical | , | Now Asante Solutions |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Caidya | Shanghai, China | Clinical Research Organization |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| OccuRx | , | Merged into Certa Therapeutics |
| Abbott | Irving, TX | Devices |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| RoslinCT | Edinburgh, UK | Stem Cells |
| , | Renamed Kyntra Bio, Jan 2026 | |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| BHR Pharma | , | Subsidiary of Besins |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| Solvanix | , | Shut down Nov 2023 |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Islet Sciences | , | Gone |
| Doctor Pack | Bangalore, India | Packaging |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| AlphaMab Oncology | Suzhou, China | Biologics |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| MedGyn Products | Westmont, IL | OBG Devices |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| TFS | Lund, Sweden | Clinical Research |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| , | Website messed up, single employee, Dec 2025 | |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Regulome | , | Gone 2006 |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| Zai Lab | Suzhou, China | Small Molecules |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| Calyx Pharma | Mumbai, India | APIs |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Confer Health | , | Shut down 2021 |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Boragen | , | Renamed Reactive Biosciences |
| Zensun | , | Website gone Jan 2019, Chinese company |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Vivifi Life Sciences | Bangalore, India | Generics |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Sprna | , | Website gone Jan 2020, no info |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| , | Shut down Oct 2025 | |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| IncellDx | , | Renamed HealthBio AI |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Ona Therapeutics | Barcelona, Spain | Cancer Therapies |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| Karo Bio | , | Renamed Karo Pharma |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Jaleva Pharmaceuticals | , | Gone |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| , | Renamed Novakand Pharma, Sep 2025 | |
| Global Cell Solutions | , | Gone Apr 2018 |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| QuantaBio | Beverly, MA | PCR equipment |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| , | Website down Jan 2026 - May 2026 | |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Noucor Health | Barcelona, Spain | Small Molecules |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| OriMAbs | , | Gone post 2022 |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| , | Website down Dec 2025 - Apr 2026 | |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| numares | Houston, TX | Clinical Diagnostics |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| , | Pivoted to Crypto, Oct 2025 | |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| Omniseq | , | Acquired by LabCorp, 2021 |
| NewHeart Devices | , | Gone |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Maplehurst Genetics International | , | Website gone |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| , | Assets being sold off May 2026 | |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| RegenoCELL Therapeutics | , | Presumed gone |
| Eargo | San Jose, CA | Hearing Aids |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Getinge | Wayne, NJ | Medical Technology |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Vante BioPharm | , | Rebranded at Sebra |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| Lyndra | Lexington, MA | Month-long Drug Delivery |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Baxter | Marion, NC | Medication Delivery |
| , | Website down Feb 2025 - Dec 2025 | |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Deinove | , | Bankrupt Mar 2023 |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| , | Shut down Oct 2024 | |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Twistnostics | , | Renamed Scanogen |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| EndoSphere | , | Gone pre-2011 |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Monobind | Lake Forest, CA | IVD |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| Axbio | Santa Clara, CA | Biochips |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| GeneSeek | , | Bought by Neogen |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| , | Renamed Numerion Labs, Oct 2025 | |
| OraPharma | , | Owned by Valeant |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| Convergen LifeSciences | , | Renamed Genprex |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| Trophea | , | Liquidated, Dec 2019 |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| BioAMPS | , | Gone |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| TeutoCell | , | Renamed Xell, 2014 |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| Roxall | , | No news 2019 - May 2025 |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Infectex | , | Website taken over May 2020 |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| , | Website down Aug 2025 - Jan 2026 | |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| Virscio | New Haven, CT | Contract Research & Consulting |
| , | Shut down Jul 2014 | |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Howfond | , | Website gone, Jul 2015 |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| GemoPharm | , | No news 2017-2022 |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Grannus Biosciences | , | Gone |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| pHion Therapeutics | , | Winding down Mar 2025 |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| ViaCord | , | Part of PerkinElmer |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| Leucid Bio | London, UK | Cell Therapy |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Getinge | Plewiska, Poland | Medical Technology |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| GlycoRegImmune | , | Changed name to GRI |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| Cytovale | South SF, CA | Sepsis Detection |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Bangalore, India | Contract Chemistry Services | |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| LinaTech | Suzhou, China | Cancer treatment device |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| DelSite | , | Bankrupt |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| , | Acquired by IQVIA | |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| NeuMedics | , | Website taken over by massager sales |
| Redpoint Bio | , | Inactive |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| AMRI | , | Renamed Curia, Jul 2021 |
| LipimetiX Development | , | Website gone, Jan 2020 |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Ribon Therapeutics | , | Shut down May 2024 |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| Vanguard Therapeutics | , | |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Rallybio | New Haven, CT | Therapeutics |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Wheaton | , | Renamed DWK Life Sciences |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Telo Genomics | Toronto, ON | Diagnostics |
| Biovertis | , | Acquired by Deinove, May 2018 |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| , | Renamed Helyx Industries | |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| Avineuro | , | Website taken over Feb 2024 |
| PreciThera | , | Website taken over, Dec 2021 |
| OperaCRO | , | Now part of Tigermed |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Genta | , | Liquidation 2012 |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| Calico | South SF, CA | Aging treatments |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Animas | , | Shut down, Oct 2017 |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Karykion | , | Website outdated, doesn't seem serious |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| Spring Discovery | , | Renamed Spring Science |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Alliqua | Langhorne, PA | Hydrogels |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Vernacare | Newtown, UK | Surgical Devices |
| Vernacare | Worksop, UK | Surgical Devices |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Lupin | Maharashtra, India | Generics |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Advantagene | , | Renamed Candel Therapeutics |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Oxitope | , | Shut Down Feb 2019 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Neuro3 Therapeutics | Cambridge, | Small Molecules, siRNA |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Getinge | Fairfield , NJ | Medical Technology |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| Adynxx | , | Website taken over Sep 2020 |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Opentrons | New York, NY | Lab Automation Robots |
| , | Website down Jan 2026 - May 2026 | |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| Celula | , | Acquired by NeoSeq |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Keenova | Hazelwood, MO | Small Molecules |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Zomanex | , | Gone Oct 2019 |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| Madera Biosciences | , | Shut down Aug 2020 |
| Repco Development Technologies | , | Renamed 3Dispense |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| ProSci | Poway, CA | Antibodies, etc. |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| Tempered Biosciences | , | Absurd website has to be gone |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Angelica Therapeutics | , | Gone 2018 |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| Luvak Lab | , | Dissolved 2013 |
| CelerDx | , | Tiny startup that went nowhere |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Pharmascience | Montréal, QC | Generics |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| ClinOne | Needham, MA | Clinical Patient Platform |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| TRPblue | , | Shut down Dec 2023 |
| Alnis BioSciences | , | No info |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| MakroCare | San Francisco, CA | Drug Development Partner |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Spine View | , | Gone |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| TissueNetix | , | Gone Feb 2018 |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Bard1 | , | Renamed INOVIQ |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| OncoQr | , | No news 2017 - Oct 2024 |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Zars Pharma | , | Acquired by NuVo Research |
| PX Biosolutions | , | Gone |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| Roche | Penzberg, Germany | Diagnostics |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| , | Renamed Trace Biosciences | |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Anaheim Clinical Trials | , | Now CenExelACT |
| Attralus | Naples, FL | Amyloidosis Treatments |
| MGI Tech | Shenzhen, China | Sequencing |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| , | Website down Dec 2025 - Apr 2026 | |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| CorWave | Clichy, France | Blood Pumps |
| US Genomics | , | Now PathoGenetix |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| , | Website down Jan 2026 - May 2026 | |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Pathens | , | Website hijacked Sep 2020 |
| Waters | Milford, MA | Chromatography & Chemistry |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| T-Ray Science | , | Renamed Verisante |
| Qualiber | , | Presumed inactive, website gone |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| AniLocus | Germantown, MD | Preclinical CRO |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Curexsys | , | Dissolving, Jul 2024 |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| Biocious Life Sciences | , | Now Agilent |
| EMS | Hortolândia, Brazil | Small Molecules |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| , | Renamed Ensera, Oct 2025 | |
| Genestack | Cambridge, UK | Genomics operating system |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| Adlon Therapeutics | , | |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| Soin Neuroscience | , | Seems like one guy |
| Avistone | Beijing, China | Precision Oncology |
| DDi | Princeton, NJ | Clinical Software |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| ERT | , | Renamed Clario, Nov 2021 |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| A2IDEA | , | Only employee left Jan 2024 |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| Simondr | , | Website gone, President has new job |
| , | Website down Sep 2025 - Dec 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| BioMAS | , | Ceased operating, Jul 2016 |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Lacerta Therapeutics | , | Shut down May 2024 |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Olio Labs | San francisco, CA | Software to de-risk clinical trials |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Boston Biokeys | , | Gone June 2017 |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| , | Acquired by Maverix Medical, Dec 2023 | |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Gerostate Alpha | , | Shut down Dec 2024 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| Compugen | Holon, Israel | Biologics |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| , | Winding down Jan 2026 | |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| , | Filings late Mar 2025 - Feb 2026 | |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| ImmuVen | , | Website gone, Dec 2015 |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Nuevolution | , | Bought by Amgen May 2019 |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Protox Therapeutics | , | Now Sophiris Bio |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Acumed | Madrid, Spain | Medical Implants |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| American Biooptics | , | Renamed Avivo BioOptics |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Ambu | Ballerup, Denmark | Medical Devices |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| Effipharma | , | Marked as closed by Google |
| ProPharma Group | Raleigh, NC | Consulting |
| KAI Research | , | Acquired by Navitas Life Sciences |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| Invectys | Paris, France | DNA Vaccine |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Seneb Biosciences | , | Gone 2017 |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| BioPhyZica | , | Gone 2016 |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Resilience | San Diego, CA | Biomanufacturing |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Axplora | Shanghai, China | Purification Systems |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| CTG Pharma | , | Gone |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| Resilience | Hamilton, OH | Biomanufacturing |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| Protelight Pharmaceuticals | Jiangyin, China | Peptide and Small Molecules Therapies |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Scientific Industries | Bohemia, NY | Lab equipment |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Cebix | , | Shut down, Feb 2015 |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Gataca | , | Gone |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Website down Dec 2025 - Apr 2026 | |
| NKT Therapeutics | , | Shut down May 2021 |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| K2M | , | Acquired by Stryker, Nov 2018 |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| , | Acquired by Scantox, Sep 2024 | |
| , | Renamed Hermes Biosciences | |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| AntiOp | , | Tech sold Jun 2015 |
| CanCure | , | No news 2017 - 2024 |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| , | Acquired by EPI, Mar 2022 | |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| ChondroGene | , | Now GeneNews |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Forge Biologics | Grove City, OH | Biologics |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| HpVac | , | Renamed Atopia Therapeutics |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Xeris Biopharma | Chicago, IL | Injectables |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| InterX | , | Acquired by NeoTX, May 2022 |
| Medtronic | Danvers, MA | Medical Devices |
| Bacthera | , | Liquidating, Feb 2025 |
| Salus Bioscience | , | Forfeited in CA |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Celerion | Tempe, AZ | Clinical Research |
| Ergomed | Cologne, Germany | Clinical Research |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| , | Website down Jan 2026 - May 2026 | |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Veryan Medical | Galway, Ireland | Helical Stent |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Hovione | Macau, China | Contract Manufacturing |
| Abbott | Altavista, VA | Nutrition |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| West-Ward | , | Now part of Hikma |
| VieVax | , | Gone Jan 2007 |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| CytRx | , | Renamed LadRx Sep 2022 |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Procos | Cameri, Italy | Contract Manufacturing |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Abselion | Cambridge, MA | Biologics Quantification |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| CoMind | London, UK | Non-invasive brain monitoring system |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| 4HF Biotec | Freiburg, Germany | Anti-cancer Treatments |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| SanBio BV | Uden, Netherlands | Antibodies |
| QuA Vodis | , | Gone |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| Getinge | Vendôme, France | Medical Technology |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| ICN Pharmaceuticals | , | Now Valeant |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Oncovista | , | Dormant 2016 |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Senetek | , | Not sure what happened, no site, seem gone |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| Medelis | Ypres, Belgium | Clinical Research |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Piramal | Hyderabad, India | CDMO |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Nile Therapeutics | , | Merged with Capricor |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| VIVUS | Campbell, CA | Small Molecules |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| O-Ray pharma | , | Inactive Jun 2022 |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Gilead | Mississauga, ON | Small Molecules |
| Lavipharm | East Windsor, NJ | Small molecules |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| , | Liquidating, Mar 2025 | |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| APSciences | , | Website gone Aug 2022 |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| Signant Health | Horsham, PA | eClinical Solutions |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Getinge | Orléans, France | Medical Technology |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Avenge Bio | , | Shut Down Jul 2024 |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| Analiza | Cleveland, OH | Physicochemical Services |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Inventiva | Daix, France | Small Molecules |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Heart Tronics | , | Effectively defunct after scandal |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Aerogen | Galway, Ireland | Nebulizers |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| , | Website down Jan 2026 - May 2026 | |
| Vascular Genesis | , | Website gone Aug 2022 |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Genmab | Plainsboro, NJ | Biologics |
| Sage Science | Beverly, MA | DNA Fractionation |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| Iquity Labs | , | Merged into Decode Health |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| Piramal | Morpeth, UK | CDMO |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| Vision Genomics | , | Website Gone, Jul 2016 |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| Cira Discovery | , | Website copyright 2003 |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Roche | Mannheim, Germany | Diagnostics |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| Saghmos Therapeutics | , | |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Envision Pharma | , | Merged with UBC |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| Eternans | , | Shut down Jul 2022 |
| Neurosave | , | Gone 2018 |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Antisoma | , | Became investment company |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| , | Gone Mar 2024 | |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Vernacare | Bolton, UK | Surgical Devices |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Azad Pharma | Montreal, QC | APIs, generics |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| CeQur | Luzern, Switzerland | Insulin pump |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Proteome Sciences | Surrey, UK | Proteomics |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Parexel | Sheffield, UK | Clinical Research |
| genOway | Lyon, France | Rat and cell models |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Gene Signal | , | Bankrupt, Apr 2021 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| IMMY | Norman, OK | Fungal Diagnostics |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Groove Biopharma | , | Gone 2015 |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Lusochimica | , | Owned by Menarini |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| Commence Bio | , | Gone 2018 |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| Combs Lab | , | Website gone Dec 2016 |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| Palmaz Scientific | , | Bankrupt, 2016 |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Lannett | Trevose, PA | Generic Small Molecules |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| , | mRNA Cell Therapy combo | |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Pharmaron | Xi'an, China | R&D Services |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| Califia Bio | , | Shut down May 2020 |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| , | Website down Oct 2025 - Feb 2026 | |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| ReactDx | Melbourne, FL | Wireless Monitors |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| Excalipoint Therapeutics | Shanghai, | |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| ProPharma Group | Westlake, OH | Consulting |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| , | Shutdown Oct 2025 | |
| Allievex | , | Shut down Feb 2025 |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Bausch Health | Laval, QC | Small Molecules |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| Vesper Medical | Wayne, PA | Venous Stent |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Neural Analytics | , | Renamed NovaSignal |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| algorithmRx | , | Now Venebio |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| Serometrix | , | More of an aspiration than a company |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| Lyman Biopharma Consulting | , | Switched to writing |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Histide | Montpellier, France | Cell Recoding Molecules |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Evvy | New York, NY | At-home vaginal microbiome test |
| Relevant Bio | , | Shut Down Oct 2023 |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Minimally Invasive Devices | , | Shut down |
| preclinics | Eystrup, Germany | Contract Research |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Metrohm | Houston, TX | Lab Data Management Software |
| OraSure | Bethlehem, PA | Diagnostics |
| Prokarium | London, UK | Oral Vaccines |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Kulira Technologies | , | Website Gone Oct 2016 |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| Vodori | Chicago, IL | Commercial Content Software |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| IDM Pharma | , | Acquired by Takeda |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| , | Acquired by Fujirebio, 2022 | |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| XO1 | , | Bought by J&J, Mar 2015 |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Unilife | , | Bankrupt, Apr 2017 |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| , | Acquired by Versiti, Jul 2023 | |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| VaxNewMo | , | Renamed Omiose |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Balance Therapeutics | , | Gone late 2020 |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| Coeptis | , | |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| , | Website down Jun 2025 - Dec 2025 | |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Alumis | South SF, CA | Autoimmune Treatments |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Ebewe Pharma | , | Now Sandoz |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Immune Technology Corp | New York, NY | Virology research products |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| , | Website taken over Mar 2026 - Apr 2026 | |
| Precision Research Institute | , | Shut down Apr 2024 |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| Gensia Sicor | , | Renamed Sicor |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| Abbott | Mississauga, ON | Diagnostics |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Qardio | Covina, CA | Portable Heart Monitors |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Maxivax | , | Renamed Release Therapeutics |
| Gensco Pharma | Doral, FL | Transdermals |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Averion | , | Now Aptiv |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Epixis | , | Acquired by VBI Vaccines |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| MabCo | , | Renamed Agenix |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Oncology Clinical Research | , | Gone |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Vista.ai | Palo Alto, CA | MRI Software |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| Proteotech | , | Website gone Jul 2015 |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Biomendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| MabSpace Biosciences | , | Renamed Transcenta |
| Curia | Aurengabad, India | Contract Development, Manufacturing |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| CSSi | , | |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Slainte Bioceuticals | , | Gone |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| Blu Biotech | , | Website down May 2023, CEO gone |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Sanofi | Paris, France | Small Molecules |
| Gerinda Therapeutics | , | Gone 2009 |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| ArKal Medical | , | Gone 2012 |
| Pharma Medica | Toronto, ON | Clinical Services |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Cibiem | , | Shut down May 2021 |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| ProPharma Group | Windsor, ON | Consulting |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| Splice Histology | Worcester, MA | Histopathology Services |
| Lung Bioengineering | , | Part of United Therapeutics |
| Terpenoid Therapeutics | , | Gone |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| OSI Pharmaceuticals | , | Bought by Astellas |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| Serentis | , | Website Gone |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Surgisense | , | Presumed gone |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Actome | Freiburg, Germany | Protein Quantification |
| ApoVax | , | Shut down Jul 2014 |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Nuredis | , | Shut Down Apr 2021 |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Restek | Bellefonte, PA | LCGC Equipment |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| Proteintech | Rosemont, IL | Research Antibodies |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Satoris | , | Bought by Rules-Based Medicine |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Weave | St. Louis, MO | Regulatory Submission Consulting |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Institute for Drug Discovery | , | Gone |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Hemadvance | , | Gone |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Cellink | Kyoto, Japan | Bioprinting |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| Trilobio | San Francisco, CA | Lab Automation |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Techne | , | Part of R&D Systems |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| MMI Genomics | , | Assets bought by Neogen |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| Medipacs | , | Shut down Jul 2024 |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Johari Medtech | Jodhpur, India | Medical Devices |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| Meditrial | New York, NY | Clinical Services, Software |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| Lavipharm | Peania Attica, Greece | Small molecules |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Cell Genesys | , | Merged with BioSante |
| Hybrigenics Services | , | Renamed ATON Group |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Norac Pharma | Azusa, CA | API Manufacturing |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| AxoGlia Therapeutics | , | Ran out of money |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| , | Seems renamed to Lusis Biosciences | |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| IDRx | , | Acquired by GSK, Feb 2025 |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Altasciences | Harleysville, PA | Contract Research |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Part of Genesis | |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| Lucena | , | Failed |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| Acumed | Hampshire , UK | Medical Implants |
| hVIVO | London, UK | Viral Services |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Existence Genetics | , | Bankrupt Dec 2012 |
| , | Website down Oct 2025 - Feb 2026 | |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Celavie Biosciences | , | Shut down Mar 2024 |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Vascular Biogenics | , | Now VBL Therapeutics |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| Ventaleon | , | Shut down 2020 |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Kerecis | Arlington, VA | Wound Healing |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Otsuka | Tokushima, Japan | Small Molecules |
| , | Acquired by Sartorius, Apr 2025 | |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| , | Website down Oct 2025 - Feb 2026 | |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Synlogic | , | Shut down Sep 2024 |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| CardiRen Biomedical | , | Gone Aug 2017 |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| XtalPi | Shenzhen, China | AI Drug Design |
| , | Inactive May 2025 | |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| Apoptos | , | Acquired by Receptos |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| , | Website down Dec 2025 - Apr 2026 | |
| Kura Oncology | San Diego, CA | Small Molecules |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Kuano | Cambridge, UK | AI Drug Discovery |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| Santen | Nara, Japan | Ophthalmics |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| Carrington Labs | , | Changed Name to DelSite |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| Graybug | , | Now Graybug Vision |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| VLST Corp | , | Wound Down, Jun 2013 |
| Ahmedabad, India | Clinical Trials | |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| Endothelix | , | Now owned by American Heart technologies |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| , | Website down Dec 2025 - Apr 2026 | |
| Acylin Therapeutics | , | Assets sold 2014 |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Rheos Medicines | , | Shut down Dec 2022 |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Altasciences | Laval, QC | Contract Research |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| Celunol | , | Merged with Diversa to become Verenium |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| AL-S Pharma AG | , | New Dec 2016, no site Aug 2018 |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Biovail | , | Merged with Valeant |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Accellacare | Rocky Mount, NC | Clinical Research |
| , | Selling pipeline, winding down Jul 2025 | |
| Prochon Biotech | , | Acquired by Histogenics |
| , | Website down Jun 2025 - Dec 2025 | |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| BioDevek | , | Formerly LabCentral, seems gone |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| US Labs | , | Bought by Labcorp |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| , | Website down Jan 2026 - May 2026 | |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| Pharmion | , | Acquired by Celgene 2007 |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Celerion | Lincoln, NE | Clinical Research |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| Altan Pharma | , | Acquired by Ethypharm |
| Biotel | , | Acquired by CardioNet, 2010 |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Artimplant | , | Bankrupt, 2013 |
| Alphatec Spine | , | Renamed Atec Spine |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Unigene Laboratories | , | Closed 2013 |
| , | Website down Jan 2026 - Apr 2026 | |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| Vrata Therapeutics | Cambridge, | |
| Univfy | Los Altos, CA | IVF reports |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| , | No news 2020 - Apr 2026 | |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| Formurex | Stockton, CA | Contract Research |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| RenovoRx | Mountain View, CA | Catheters |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Marpē Therapeutics | , | Professor sideline |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| , | Shut down Jul 2025 | |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Warnex | , | Merged into DIAGNOS Inc |
| VasculoMedics | , | Gone 2019 |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Spirox | , | Bought by Stryker, Jul 2017 |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| , | Winding down Jan 2026 | |
| Moximed | Fremont, CA | Joint treatment |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| , | Renamed Verge Medical, Mar 2025 | |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| CONMED | Largo, FL | Surgical, Medical Devices |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| , | Website down Oct 2025 - Jan 2026 | |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| NIOX | Uppsala, Sweden | Asthma management device |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| , | Acquired by Stryker, Oct 2024 | |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Northway Biotech | Waltham, MA | Contract research |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| American Stem Cell | , | Changed name to Targazyme |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| CO.DON | Leipzig, Germany | Cell Therapies |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| Hemanext | Lexington, MA | Transfusion Technologies |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| Obexia | , | Gone |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| MiNA Therapeutics | London, UK | Small activating RNA |
| SteriTech | Sligo, Ireland | Process Equipment |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Veryan Medical | Horsham, UK | Helical Stent |
| Typharm | Norwich, UK | Generics |
| Novotech | Bangkok, Thailand | Clinical Research |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| Curia | Bon-Encontre, France | Contract Development, Manufacturing |
| , | Website down Dec 2025 | |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| , | Renamed Kapadi, Nov 2025 | |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| ProUroCare Medical | , | Gone |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| , | Website down Aug 2025 - Jan 2026 | |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| Organix | Woburn, MA | Contract Research & Development |
| Ufovax | , | Renamed Uvax Bio? |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| , | Website down Oct 2025 - Feb 2026 | |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| CisThera | , | Shut down Jan 2023 |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Centocor | , | Renamed Janssen Biotech |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| RhinoCyte | , | Website moved to a marketing agency domain |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| , | Acquired by Source BioScience, Apr 2025 | |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| Pfizer | Clondalkin, Ireland | Biologics |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Kirgen | Shanghai, China | Lab Supplies |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Copley Scientific | Nottingham, UK | Test equipment |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Emulate | Boston, MA | Organs-on-chips |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| Upstate Biotechnology | , | Closed 2005 |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Getinge | Mumbai, India | Medical Technology |
| Amarin | Bridgewater, NJ | Small Molecules |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| , | Website down Jul 2025 - Dec 2025 | |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| Amniox Medical | , | Folded into BioTissue |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| Targeson | , | Website gone, Mar 2017 |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Sterling | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Ionian Technologies | , | Gone Mar 2016 |
| Getinge | Englewood, CO | Medical Technology |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Biophytis | Paris, France | Therapies for aging diseases |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Amoytop Biotech | Xiamen, China | Biologics |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Biotrin International | , | Renamed Diasorin? |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Loop Therapeutics | , | Shut down Jan 2021 |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| OxOnc Development | , | Website gone Apr 2018 |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Acuvax | , | Pivoted to investments, 2014 |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Iktos | Paris, France | AI for New Drug Design |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| Stryker | San Jose, CA | Medical Devices |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Meissner | Castlebar, Ireland | Lab Systems |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| Nostrum Laboratories | Kansas City, MO | Generics |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| GenoImmune | , | |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| Nexus BioPharma | , | No news 2017-2022 |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Intica Biomedical | , | Bankrupt 2014 |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Delta4 AI | Schindellegi, Switzerland | AI Drug Discovery |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| Spear Bio | Woburn, MA | Immunoassays |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Trudell Medical | London, ON | Inhalation Devices |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| NK CellTech | Shanghai, China | Cell Therapies |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Mirador Biomedical | , | Shut Down 2019 |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| LinKinVax | , | Rebranded as EnnoDC |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| Crown Bioscience | Beijing, China | Drug Development |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Oct 2025 - Feb 2026 | |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| , | Website down, COO gone Oct 2025 | |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| Traversa Therapeutics | , | Bankrupt |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Admescope | Oulu, Finland | ADME-tox services |
| , | ||
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| arGEN-X | , | Older name for Argenx |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| , | Website down Aug 2025 - Jan 2026 | |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| , | Website down Sep 2025 - Dec 2025 | |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| rhealth | Bedford, MA | Diagnostics |
| FFE Therapeutics | , | Shut down Dec 2013 |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| BioArra | , | Bought by VWR Nov 2016 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Sania Therapeutics | London, UK | CNS Treatments |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Antigenics LLC | , | Now Agenus |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| Oak BioSciences | , | Shut down Nov 2024 |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| Cancer Insight | , | Renamed LumaBridge |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Cadex Genomics | , | Shut down Jul 2024 |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Virapur | , | Acquired by Microbiologics, 2017 |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| FocalOne | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| Medion Diagnostics | , | Bought by Grifols? |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Nido Surgical | , | Shut down Apr 2022 |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Predictive Therapeutics | , | Renamed NeoTX |
| Esoterix | , | Bought by LabCorp, May 2005 |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| BG medicine | , | Gone 2019 |
| Dey LP | , | Bought by Mylan 2007 |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| Piramal | Pithampur, India | CDMO |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| , | Website down May 2025 - Dec 2025 | |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| , | Website down Jul 2025 - Dec 2025 | |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| , | Rebranded as VivoSim, Apr 2025 | |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| Sicor Biotech | , | Bought by Teva 2004 |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Chennai, India | Contract Development Organization | |
| Curamir Therapeutics | , | Shut down 2020 |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Perlegen | , | No Site |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| Adheren | , | Gone, 2016 |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| Point Biomedical | , | Liquidated Jul 2008 |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| Cytochroma | , | Acquired by Opko Health |
| Hasten Pharma | Hefei, China | Small Molecules |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Neuroservices-Alliance | Aix-en-Provence, France | Contract Research Organization |
| Xenomics | , | Now TrovaGene |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| , | Renamed Envue, Feb 2026 | |
| Novotech | Bangalore, India | Clinical Research |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Sequel Pharmaceuticals | , | Gone |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| , | Acquired by Aptean, Oct 2016 | |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| Pharming Group | Leiden, Netherlands | Biologics |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Grove Instruments | , | Shut Down June 2017 |
| Hemanext | Avon, MA | Transfusion Technologies |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| BioDatomics | , | Website gone Jan 2019 |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Karius | Redwood City, CA | Diagnostics |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Odyssey Thera | , | Shut down 2014 |
| Hutchmed | Hong Kong, China | Oral drugs |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| XW Laboratories | , | Renamed XWPharma |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| StaphOff Biotech | , | Shut down 2017 |
| Quench Bio | , | Wound down Mar 2021 |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| F2G | Cheshire, UK | Antifungals |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Getinge | Gothenburg, Sweden | Medical Technology |
| , | Renamed Alethio Therapeutics | |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| , | Website down Jan 2026 - May 2026 | |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Remo CRO | , | Seems to be rebranded as Supeira |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| Gentian USA | Moss, Norway | IVD Products |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| , | Website down Jun 2025 - Oct 2025 | |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| Indero | Montréal, QC | Dermatology Clinical Research |
| ExThera Medical | Martinez, CA | Blood filtration |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Zai Lab | Shanghai, China | Small Molecules |
| Getinge | Tournefeuille, France | Medical Technology |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| ThauMDx | , | Closed down 2003, out of cash |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| NeuroTransit | , | Behind on taxes in CA |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Vedere Bio II | , | Shut down Mar 2023 |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Nanosonics | Manchester, UK | Ultrasound |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Genmab | Utrecht, Netherlands | Biologics |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Vascular Technology | Nashua, NH | Surgical Devices |
| Siga | Corvallis, OR | Small Molecules |
| Tychan | , | Liquidated early 2022 |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| , | Website down Aug 2025 - Jan 2026 | |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Quakertown, PA | Microionization CDMO | |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Nexus Spine | Draper, UT | Spinal Implants |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Zyagen | San Diego, CA | Life Science Reagents |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| AuraSense Therapeutics | , | Renamed Exicure |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| , | Renamed Cordica Medical, Jan 2026 | |
| HawkCell | Lyon, France | MRI Research Technology |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| AlphaVax | , | No employees on LI. Not sure active |
| GliaMed | , | Website copyright 2009, seems defunct |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Launchpad Therapeutics | , | |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Onkor Pharma | , | 10 year old company with no product or website |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| Elixir Pharmaceuticals | , | Gone |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Baxter | Alliston, ON | Medication Delivery |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| GlycoSolutions | , | Closed Aug 2015 |
| PolyMedix | , | Bankrupt Apr 2013 |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| PathAI | Boston, MA | AI Powered Pathology |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Boston Scientific | St. Paul, MN | Medical Devices |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Medrobiotics | , | Bankrupt, May 2024 |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| DesignMedix | , | Shut down Aug 2020 |
| Zylacta | , | No news 2015 - Oct 2024 |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Cue Biopharma | Boston, MA | Immunotherapy |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| , | Renamed Carvolix, Feb 2026 | |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| Cryoniss | Deeside, UK | Bio Banking |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Kirax | , | Website Gone |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Pinnaxis | Noida, India | Pharmacovigilance |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| Curry Pharmaceuticals | , | Closed 2008 |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Dirui Industrial | Changchun, China | Automated Assays |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| iBio | San Diego, CA | Antibody Therapies |
| Sirana Pharma | , | Merged with Apexis Bio |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Intelliseq | Kraków, Poland | Genome Informatics |
| CytoVera | , | Gone June 2017 |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| ObvioHealth | New York, NY | Clinical Study Software |
| Applied NeuroSolutions | , | Gone |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Synaptrix | New York, NY | Brain-Computer Interface |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| EpiFinder | , | Gone May 2025 |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Octapharma | Vienna, Austria | Plasma Products |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| AlloThera | , | Gone, 2018 |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| CTIBIOTECH | Meyzieu, France | Tissue Sample |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Piramal | Mumbai, India | CDMO |
| Lavipharm | Paris, France | Small molecules |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Rosedale Medical | , | Now Intuity Medical |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| Roowin | Riom, France | Chemical Synthesis |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| Cellex | , | Presumed Gone |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| PROGEN | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Octane Biotech | Lucknow, India | Generics |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| Nocimed | , | Renamed Aclarion |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| XellSmart | Suzhou, China | Cell Therapy |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Oncorus | , | Liquidated, Jun 2023 |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Quantificare | Maringa, Brazil | Medical Imaging |
| Bayer | Mailand , Italy | Small Molecules |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Cellnovo | , | Bankrupt, Jul 2019 |
| CytoLogix | , | Gone, Sep 2012 |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| BIOMODEX | , | Acquired by Mentice |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| PathoGene | , | Website taken over, Oct 2017 |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| Basecamp Research | London, UK | AI-Biology Data |
| Elixir Medical | Milpitas, CA | Stents |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| WiseGene | , | Website gone jan 2020 |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Abgenix | , | Bought by Amgen 2006 |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| Aadigen | , | Renamed Aanastra |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Metabolex | , | Now CymaBay Therapeutics |
| Kar Bioanalytical | , | Seem gone |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| PhotoThera | , | Ceased operations Dec 2012 |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Novotech | Sydney, Australia | Clinical Research |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| , | Website down Jul 2025 - Dec 2025 | |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| JD Bioscience | Seoul, Korea | Small Molecules |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Atherotech | , | Shut down Feb 2016 |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| sRNA Dx | , | aka sRNAlytics |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| bioRASI | Aventura, FL | Clinical Research |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| Nura Bio | South SF, CA | Small Molecule |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| Cholestech | , | Now Alere |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| MikrobEX | , | Renamed Rebiotix |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Hana Biosciences | , | Now Talon Therapeutics |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Integrated Genomics | , | Changed to Igenbio |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| Dharma Therapeutics | , | Gone, 2013 |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| InsightRX | San Francisco, CA | Dosing Model |
| Therorna | Beijing, China | RNA Therapies |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Medistem | , | Bought by Intrexon Dec 2013 |
| AliveDx | Eysins, Switzerland | Diagnostics |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| , | Website taken over Mar 2026 | |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| , | Merged with Vizgen, Oct 2024 | |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| Jina Pharmaceuticals | , | |
| Novartis Animal Health | , | Acquired by Lilly |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| , | Website down Jul 2025 - Oct 2025 | |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| Greppo Technologies | , | Renamed Verix Health |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| Apalexo Biotechnologie | , | No info, probably gone |
| TransCellular Therapeutics | , | Gone 2019 |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| PharmaGap | , | Shut down 2013 |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| BioLegacy Research | San Diego, CA | Contract Research |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| Therics | , | Acquired by Integra |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| , | Redirecting to Siemens, Feb 2026 | |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| LifeQual Pharmaceuticals | , | Website Gone |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Sanovel | Istanbul, Turkey | Generics |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Hovione | Mumbai, India | Contract Manufacturing |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Sequoia Pharmaceuticals | , | Folded |
| , | Acquired by MannKind, Oct 2025, $296M | |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| Eyetech | , | Website Gone 6-16-12 |
| , | Website down Oct 2025 - Feb 2026 | |
| Curia | León, Spain | Contract Development, Manufacturing |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Spriaso | , | No news 2019 - May 2025 |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Target Medicals | , | No news 2016 - Oct 2024 |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Acretia | , | Gone |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| IR2Dx | , | Gone, 2019 |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Ergomed | Prague, Czech Republic | Clinical Research |
| , | Website down Jul 2025 - Jan 2026 | |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| Sunol Molecular | , | Assets sold 2005 |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Cytheris | , | Out of business 2013 |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Getinge | Feldkirchen, Germany | Medical Technology |
| FineHeart | Pessac, France | Heart Failure Device |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| ImmuneMed | , | Shut Down |
| Genaera | , | Dissolved |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Sanofi | Midrand, South Africa | Biologics |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| , | ||
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Azopharma | , | Bankrupt, Apr 2010 |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Kinaxo | , | Bought by Evotec |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Rhaeos | Evanston, IL | Shunt Monitor |
| , | Acquired by Ligthouse Lab Services | |
| GMP-Orphan France | , | Renamed Orphalan |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Getinge | Merrimack, NH | Medical Technology |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| Salvat | Barcelona, Spain | Small Molecules |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| EmpowerPharm | , | Shut down |
| , | Acquired by Alcon, Sep 2025 | |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Novitium Pharma | East Windsor, NJ | Generics |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Pfizer | Puurs, Belgium | Packaging |
| CBH ClinTrials | , | now CenExelCBH |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| Ipsen | Wrexham, UK | Biologics |
| , | Website down Jul 2025 - Jan 2026 | |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| Provecs Medical | , | Gone Nov 2019 |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Stryker | Flower Mound, TX | Medical Devices |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Catalyst Clinical Research | Schiphol, Netherlands | Clinical research solutions to the global biopharmaceutical industry |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| Pfizer | Kalamazoo, MI | Manufacturing |
| MyOme | Palo Alto, CA | Genomic Analysis |
| Medicomp | , | Renamed ReactDx |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| Imalux | , | Ceased Operations, Apr 2014 |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| 76Bio | , | Shut down Jan 2025 |
| , | Website down Jan 2026 - Mar 2026 | |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Louisville Bioscience | , | Now LBIdx |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Nucryst | , | Bought by Smith & Nephew |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| AIBioTech | , | Assets auction, Aug 2017 |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Xori | , | Antibody Platform sold between 2011-2014 |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Ikotech | , | Closed Dec 2015 |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| Octapharma | Springe, Germany | Plasma Products |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| LFB | Paris, France | Plasma derived drug products |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Akermin | , | Closed |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| , | Website down Jan 2026 - Mar 2026 | |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| NextGen Sciences | , | Defaulted, sued by employees |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| , | No website updates since 2013 as of Dec 2025 | |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Geron | Foster City, CA | Small Molecule |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Santen | Osaka, Japan | Ophthalmics |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Metris Therapeutics | , | Presumed Gone |
| Alte Biosciences | , | Gone, Apr 2016? |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Sebra | Tucson, AZ | Tube Sealer |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| , | Website down May 2025 - Dec 2025 | |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Alxerion Biotech | , | Gone May 2021 |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| Neurokos | , | Gone. No info |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Trek Therapeutics | , | Shut down Sep 2019 |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Halloran Consulting Group | Boston, MA | Consulting |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| PegaOne | , | Centessa Company |
| GeneFab | Alameda, CA | Gene Therapy Services |
| Veramed | London, UK | Biostatistics and programming services |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Endocare | , | Website down Jan 2021 - May 2021 |
| TaliaPharm | , | Website gone, Jan 2018 |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| Alexis Biotech | , | Dissolved May 2015 |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| Lupin | Mandideep, India | Generics |
| Mindflow Design | , | Now part of MPE |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Trilations | Kontich, Belgium | Strategic Consulting |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Ampac Analytical | , | part of SK pharmteco |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Sentien Biotechnologies | , | Shut down late 2021 |
| BrainScope | Bethesda, MD | EEG characterization |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| Tikcro Technologies | , | Liquidating 2021 |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Codon Devices | , | Closed Apr 2009 |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| , | Renamed WallabyPhenox | |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Viva Biotech | Jiaxing , China | Contract Research |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Inform Genomics | , | Website Gone Nov 2018 |
| , | No news 2017 - Apr 2026 | |
| , | Pivoted to crypto, Apr 2026 | |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| Parcell Labs | , | Website Gone, Oct 2016 |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| accuFD | , | Closed Dec 2017 |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Biowarn | , | Gone |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Audubon Bioscience | Houston, TX | Biospecimens |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| NNS Clinical Research | , | Gone |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| Klogene Therapeutics | , | Gone 2019? |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| , | Website down Dec 2025 - Apr 2026 | |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| Lipid Genomics | , | Seems unserious |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Vernacare | Chorley, UK | Surgical Devices |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| AstraZeneca | New Haven, CT | Biologics |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| Nesch, LLC | , | Website gone Oct 2018 |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| , | Filings late Jun 2025 | |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| Medicure | Holetown, Barbados | Small Molecule |
| Catalyst Clinical Research | Clinton, CT | Clinical research solutions to the global biopharmaceutical industry |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| , | Shut down Mar 2026 | |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| C/M/C Biologics | , | Now CMC Biologics |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| Pirche | Grünwald, Germany | Transplant Matching |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| CellXplore | , | Gone |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Abcam | Waltham, MA | Antibodies |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| |
Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| NeoVentures | London, ON | Custom Aptamers |
| Yao Pharma | Chongqing, China | APIs, Generics |
| CytoMol (2) | , | SF-based, Looks gone |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| Lorantis | , | Merged with Celldex 2005 |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| GSL Biotech | , | Acquired by Dotmatics |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Clearbridge Biomedics | , | Renamed Biolidics |
| Roche | Basel, Switzerland | Small Molecules |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Opsonix | , | Shut down May 2018 |
| InfraReDx | Bedford , MA | Medical Devices |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Laborie | Portsmouth, NH | Medical Devices |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Trident Lifeline | Surat, India | Generics |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| , | Website taken over Feb 2026 | |
| Aplagen | , | No activity since 2008 |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| Alcon | Mississauga, ON | Eye Care Products |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| Mytos | London, UK | Automated Cell Culture |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| , | Acquired by Lonza, Apr 2017 | |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| YMC Process Technologies | Devens, MA | Purification Technology |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Sarstedt | Nümbrecht, Germany | Lab products |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| GL Technologies | San Diego, CA | Calibration Services |
| Green Cross | , | Renamed GC Pharma |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| , | Subsumed into Synoptics | |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Piramal | Aurora, ON | CDMO |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| Western Biologics | , | Dissolved, 1998 |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| , | ||
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| Cell Therapy Ltd | , | Renamed Celixir |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Altasciences | Everett, WA | Contract Research |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Axplora | Pompey, France | CDMO Services |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| Pear Bio | London, UK | Cancer Treatment Selection |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Evalve | , | Owned by Abbot Vascular |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Nteryx | , | Changed name to Ardelyx |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| CorTechs Labs | , | Renamed Cortechs.ai |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| Uncover Therapeutics | , | |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| , | Website down Nov 2025 - Apr 2026 | |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| Metis Laboratories | , | |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Curia | Origgio, Italy | Contract Development, Manufacturing |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Stryker | Mahwah, NJ | Medical Devices |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| Orthofix International | Lewisville, TX | Medical Devices |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| Getinge | Getinge, Sweden | Medical Technology |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Peptimmune | , | Liquidated 2011 |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Arginox Pharmaceuticals | , | Apparently Gone |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| SGS Quay Pharma | , | |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| Scion NeuroStim | , | Presumed gone |
| Alkermes | Waltham, MA | Small Molecules |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| Ergomed | Kiev, Ukraine | Clinical Research |
| BioTeam | Middleton, MA | Scientific IT consulting |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Nova Biomedical | Norwood, MA | Lab instruments |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Tequesta BioScience | , | Defunct |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Duramed | , | Acquired by Barr Labs 2001 |
| Biotagenics | , | Renamed MedBiome |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| , | Now Nexus Spine | |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| , | Website down Dec 2025 - Apr 2026 | |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| , | Renamed Aspen Neuroscience | |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| BioFluentLabs | , | Shut down July 2012 |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| , | Renamed Helus Pharma, Jan 2026 | |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| , | Assets Acquired by Klotho, Sep 2025 | |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| OxStem | , | Shut down 2021; Oxford spinout |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Nereus | , | Website Gone late 2013, no info |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| ImmuneXcite | , | Closed Oct 2017 |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| Makefield Therapeutics | , | Website Gone |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| 3T Biosciences | South SF, CA | TCR Therapies |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Wyeth | , | Bought by Pfizer |
| Cell>Point | , | Cant find any confirmation they are active |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Inspirata | North York, ON | Cancer Insights |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Satya | Hyderabad, India | Small Molecule |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Berlex | , | Now Bayer |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Savage Medical | , | Renamed Averto Medical |
| Clinisys | Tucson, AZ | LIMS Platform |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| PowderMed | , | Acquired by Pfizer 2006 |
| Grifols | Durham, NC | Biologics |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Apofore | , | Shut down, Dec 2015 |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| Aviria Biosciences | , | Disappeared |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| NeoPharm | , | Merged with Insys Therapeutics |
| Nano Science | , | Acquired by EAG, 2006 |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| METiS Technologies | , | |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| BA Sciences | Morrisville, NC | Analytical Services |
| , | Website down Aug 2025 - Jan 2026 | |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| MicrofluidX | , | Renamed MFX |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Avenir Pharma | , | No longer active |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Archimedes Vascular | Birmingham, | Hypertension Devices |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Accellacare | Knoxville, TN | Clinical Research |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| , | Website down Sep 2025 - Dec 2025 | |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Bioasis Technologies | , | Closing down Jun 2023 |
| Molecular Detection Inc | , | Gone 2016 |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Neocis | Miami, FL | Dental Surgery Robots |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Groton Biosystems | , | Gone before Jun 2015 |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| Adaptix | Oxford, UK | Medical imaging |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| BioCydex | , | No info 2019 - Mar 2025 |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| CatSci | Cardiff, UK | Contract Research |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Microfluidics | Westwood, MA | High shear fluid processors |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| , | Website taken over Feb 2026 | |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| Syantra | Calgary, AB | Breast cancer blood test |
| , | Website down Dec 2025 - Apr 2026 | |
| Ozgene | Bentley, Australia | Genetically modified mice |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Getinge | Rastatt, Germany | Medical Technology |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| Peritia | Morrisville, NC | Consulting |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Curia | Albuquerque, NM | Contract Research |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Zydus Cadila | Ahmedabad, India | Generics |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Boca Pharmacal | , | Bought by Qualitest |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| MediciNova | La Jolla, CA | Small Molecules |
| Pharmazz | Greater Noida , India | Small Molecules |
| Sierra Surgical | , | Shut down Feb 2019 |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| AMDL | , | Now Radient Pharmaceuticals |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| XtalPi | Shanghai, China | AI Drug Design |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Sciele Pharma | , | Bought by Shionogi |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| Cogentis Therapeutics | , | No news 2017-2023 |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation psuedo-subsidiary | |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| , | ||
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Proteom | , | Acquired by Amura Ltd |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| ZipBio | Seattle, WA | Compact Proteins |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Aspira Scientific | , | Gone Nov 2015 |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Inventa Biosciences | , | Not Active |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Cue Health | , | Shut down May 2024 |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| , | Renamed Create Medicines, Oct 2025 | |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Ortho Development | Draper, UT | Ortho Implants |
| Actylis | Port Washington, NY | Raw Materials |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| SK Biotek | , | part of SK pharmteco |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Regenerative Sciences | , | Took on Regenexx product name |
| BRAND | Wertheim, Germany | Liquid Handling |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Pathnostics | Irvine, CA | Diagnostics |
| ImmunityBio | San Diego, CA | Cellular therapy |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| , | No news 2020 - Dec 2025 | |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Waterford, UK | Medical Device Contract Manufacturing | |
| Getinge | Hechingen, Germany | Medical Technology |
| , | No news 2019 - Apr 2026 | |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Lab Owl | , | Part of Inflexion Point |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Serica Technologies | , | Bought by Allergan |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| Avecia | , | Bought by Nitto Denko |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| Allogene Therapeutics | South SF, CA | CAR-T |
| VedaLab | Cerisé, France | IVD rapid tests |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| Appili Therapeutics | Halifax, NS | Small molecule |
| ARC Medical | , | Acquired by Typenex Medical |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| , | Website down Sep 2025 - Feb 2026 | |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| , | ||
| 149 Medical | , | Shut down Dec 2022 |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| Sinusys | , | Shut down 2023 |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| XtalPi | Beijing, China | AI Drug Design |
| Peplin | , | Acquired by Leo Pharma 2009 |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| Epic Pharma | Laurelton, NY | Generics |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Itero Biopharmaceuticals | , | Website Gone |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| MindRank | Shanghai, China | AI Drug Discovery |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| SutroVax | , | Renamed VaxCyte |
| ArisGen | , | Only employee has four other jobs |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Sierra Neuropharmaceuticals | , | Not active |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| Nizyme | , | Gone Jul 2015 |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| ProteoVec | , | Website gone Jul 2015 |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| argenx | Boston, MA | Antibody therapies |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| WntResearch | , | Shell acquired by Opsy |
| Aresus Pharma | , | Seems folded in to Dermago |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Wacker | Munich, Germany | Polymers, Resins |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| Curia | Glasgow, UK | Contract Research, Development, Manufacturing |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Syneos Health | Newtown, PA | Clinical Development |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Sterling | Concord, ON | Medical Device Contract Manufacturing & Development |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| Unither Pharmaceuticals | Paris, France | CDMO |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| Delpharm | Reims, France | Contract Manufacturing |
| , | Website down Nov 2025 - Apr 2026 | |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| , | Bankrupt, ceased operations Mar 2026 | |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| Supeira | , | Website gone Mar 2023 |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Piramal | Digwal, India | CDMO |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Occam Design | Louisville, SS | Medical Device Development |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Iquum | , | Acquired by Roche, Apr 2014 |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Biokit | , | Rolled into Werfen |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Benchling | San Francisco, CA | Biotech Software |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Helsinn | Iselin, NJ | Small Molecules |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Dropshot Therapeutics | , | |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| , | Assets acquired by Alexion, Feb 2011 | |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| RapidTrials | , | Pivoted to staffing, 2017 |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| America Stem Cell | , | Changed name to Targazyme |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| OpenClinica | Needham, MA | Clinical Study Software |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Abnovo | , | Gone |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| , | ||
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Rho | Durham, NC | Clinical Research |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Expression Patholgy | , | Now OncoPlexDx |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Ciphergen | , | Now Vermillion |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Boston Scientific | Spencer, IN | Medical Devices |
| Abcam | Cambridge, UK | Antibodies |
| Bafna | Chennai, India | Generics |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Barrier Therapeutics | , | Bought by Stiefel |
| Berkshire, UK | Clinical Trial Solutions | |
| , | Website down Aug 2025 - Dec 2025 | |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Cytonome | , | Shut down Nov 2009 |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Iomai | , | Bought by Intercell 2008 |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| , | Website down Dec 2025 - Apr 2026 | |
| UVision 360 | , | Renamed Luminelle |
| Affigen | , | Liquidating Fall 2019 |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Zivena | , | Gone |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| Mott | Farmington, CT | HPLC system components, Filtration |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Clarapath | Hawthorne, NY | Pathology Device |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Neugenesis | , | Bought by Intrexon, 2011 |
| NuAire | Plymouth, MN | Lab Equipment |
| Theranos | , | Dissolving, Sep 2018 |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| Ergomed | Surrey, UK | Clinical Research |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| Valneva | Lyon, France | Antibody Discovery |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| NeuroNano Pharma | , | Gone 2018 |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| AB ANALITICA | Padua, Italy | Sequencing products |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Stada | Bad Vilbel, Germany | Generics |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| , | Website down Nov 2025 - Mar 2026 | |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Neuronax | , | Renamed Axoltis Pharma |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| PROGEN | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| Tarpon Biosystems | , | Gone by 2017 |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| , | Renamed Revr Jan 2026 | |
| Synovex | , | Renamed Adheron Therapeutics |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| LyoTechnica | , | Gone |
| Clinical Scientist Group | , | Website gone, employee gone |
| STC Biologics | Newton, MA | Services |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| , | Acquired by Lantheus, Jan 2025 | |
| Avema Pharma | , | Bought by PL Developments |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| , | ||
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Pharmaron | Beijing, China | R&D Services |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| Antitope | , | Now part of Abzena |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Formation Bio | New York, NY | AI Drug Discovery |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| T&T Scientific | , | Website gone May 2023 |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Riboxx | Dresden, Germany | RNA Products |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Olymvax | Chengdu, China | Vaccines |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| Zai Lab | Beijing, China | Small Molecules |
| IntelligentMDx | , | Shut down Feb 2015 |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Catalina Pharma | , | No info 2017-2022 |
| Novarad | Provo, UT | Imaging Software and Technology |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Invibio | Cleveleys, UK | Implants |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| MicroPort | Clamart, France | Medical Devices |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Cetero Research | , | Renamed PRACS Institute |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| AbGenomics | , | Renamed Altrubio |
| VasoRx | San Diego, CA | RNA delivery |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Cytiva | Amersham, UK | Medical Devices |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| ReproSource | Marlborough, MA | Fertility Testing |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Celest Therapeutics | , | |
| Solventum | St. Paul, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| Augmenta Biologicals | , | Website Gone May 2014 |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Curia | Tonneins, France | Contract Development, Manufacturing |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Medley Genomics | , | Website for sale Feb 2021 |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| Apolife | , | Renamed Biosavita |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| Healx | Cambridge, UK | AI Drug Discovery |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| Genlantis | , | Acquired by AMSBIO |
| , | No news 2019 - Sep 2025 | |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Rezo Therapeutics | San Francisco, CA | |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| , | Website down Jan 2026 - May 2026 | |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| , | Website down Jul 2025 - Dec 2025 | |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| BioVascular | , | 2007 website as of Mar 2019 |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| Angiosyn | , | Acquired by Pfizer 2005 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| EhmetDx | , | Renamed Ehmet Health |
| , | Seems to have shut down mid 2025 | |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| Micell Technologies | , | Seems shut down 2019 |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| Compucyte | , | Sold Assets to Thor Labs |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| Nanosonics | Sydney, Australia | Ultrasound |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| CORONIS | Athens, Greece | Clinical Studies |
| myoscience | , | Renamed iovera |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Percivia | , | Shut Down 2012 |
| LifeMax | , | Part of AmMax |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Dynacare | , | Bought by LabCorp 2002 |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Chromtech | Apple Valley, MN | Chromatography Products |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Nusano | Valencia, CA | Radioisotopes |
| BioNanomatrix | , | Renamed BioNano Genomics |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Cerba Research | Ghent, Belgium | Lab Testing |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| GenSensor | Nantes, France | Process Analytical Technology |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| PluroGen Therapeutics | , | Gone 2013 |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Sixal | , | SBIR, Presumed defunct |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| Strides Arcolab | , | Now just Strides |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| Echo | San Diego, CA | Microscopy |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Orbus Pharma | , | Website Gone |
| UniXell | Shanghai, China | Cell Therapy |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Resilience | East Norriton, PA | Biomanufacturing |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| Therix Medical | , | Seems gone |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Apollo Spine | , | Renamed G6 Spine |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| , | Acquired by Glaukos, Aug 2025 | |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| Baxter | Grosotto, Italy | Medication Delivery |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| Endovasc | , | Bankrupt 2008 |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Sorbent Therapeutics | , | Gone post 2014 |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Olon USA | Concord, OH | Contract Research |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| Inverness Medical | , | Renamed Alere 2011 |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Micrologix Biotech | , | Renamed Migenix |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Deimos Biosciences | , | |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| XBiotech | Austin, TX | Antibody Therapy |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Keenova | Dublin, Ireland | Small Molecules |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Genecure | , | Shut down Sep 2021 |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| MeiRui Pharma | , | Bought by GSK |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| CP Life Science | , | Split and became Medvacon |
| Promedior | , | Acquired by Roche, Feb 2020 |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Abazyme | , | Dissolved Jun 2017 |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Piramal | Sellersville, PA | CDMO |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| Simpirica Spine | , | Became Empirical Spine |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Accellacare | Cary, NC | Clinical Research |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Heragen | , | Gone |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| Biocode Hycel | , | Website gone |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Boston Neurosciences | , | Website down Jun 2020 |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| Sopharma | Sofia, Bulgaria | Generics |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| PhytoMedical | , | Apparently Gone |
| Aitia | Cambridge, MA | Analytics |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| DDi | Basel, Switzerland | Clinical Software |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| OptiVia Medical | , | Website looks pretty terrible |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Abogen | Suzhou, China | mRNA |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Symansis | Timaru, New Zealand | Reagents |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| Concordia Healthcare | , | Now Concordia International |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| , | Dissolved, Apr 2024 | |
| AGILeBiotics | , | Shut down 2024? |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Axonia Medical | , | Gone 2015 |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| PredictImmune | , | Shut down Nov 2023 |
| Monroe Research | Monroe, NC | Clinical Trials |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| , | Website down Dec 2025 - Apr 2026 | |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| , | ||
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Sopherion | , | Website taken over, Mar 2017 |
| Nanogen | , | Now Epoch Biosciences |
| Luye Pharma | Shanghai, China | Small Molecules |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Spinafx Medical | Toronto, ON | Steroid Injection Device |
| Ribopro | Oss, Netherlands | mRNA Services |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Bluegrass Vascular | San Antonio, TX | Vascular access system |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| Manhattan Pharmaceuticals | , | Gone |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Stada | Belgrade, Serbia | Generics |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Chiromics | , | Website now a penny stock shill |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| ArgusEye | Linköping, Sweden | Biosensors |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| SEQENS | Pune, India | Analytical method validation, API development |
| REPROMEDIX | , | Gone 2012 |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Vicus Therapeutics | , | Gone 2019 |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Neuroservices-Alliance | San Diego, CA | Contract Research Organization |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Pfizer | Surrey, UK | Consumer Healthcare |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| AFID Therapeutics | , | Gone 2012 |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| Light Sciences Oncology | , | Shut down late 2020 |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Menarini | Florence, Italy | Biologics |
| DDi | London, UK | Clinical Software |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Genomics | Oxford, UK | Human Genetics Platform |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| AtheroGenics | , | Assets Sold Off 2009 |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Affitech | , | Gone |
| Infinity Bio | Baltimore, MD | Reactome Services |
| Bayer | Bitterfeld, Germany | Small Molecules |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Tirupati | New Delhi, India | Generics |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| ViroMed | , | Renamed Helixmith |
| Merix Bioscience | , | Renamed Dendrix |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Purdue Pharma | Stamford, CT | Small Molecules |
| Nycomed | , | Acquired by Takeda 2011 |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Evoke Medical | , | Renamed DirectSync Surgical |
| Diatos | , | No website, founded 1999 |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| Plureon | , | Website gone, one employee after 17 years |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Immunosyn | , | Charged with Securities Fraud |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| Macusight | , | Effectively acquired by Santen, 2008 |
| Qool Therapeutics | , | Gone Jan 2021 |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| Myrexis | , | Liquidating 2013 |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Amorsus | , | Website Gone 8-30-13 |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| , | Renamed Motive Health, Jul 2023 | |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| Omnimmune | , | Shell company, trademark abandoned |
| SFS | Madrid, Spain | Clinical Research Organization |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Tribiosys | , | Appears defunct, likely late 2007 |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| Evidera | , | Acquired by PPD, 2016 |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| , | Acquired by hVIVO, Jan 2025 | |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Tolerx | , | Shut Down 2011 |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| 7TM Pharma | , | Gone |
| , | No news 2018 - May 2026 | |
| Orthogonal LLC | Chicago, IL | Medical device software |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| vTv Therapeutics | High Point, NC | Small molecules |
| , | Website down Nov 2025 - Apr 2026 | |
| Matritech | , | Assets bought by Matritech 2007 |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Cannabis Science | , | Seems inactive Nov 2023 |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| , | Renamed BreezeBio, Feb 2026 | |
| RxCelerate | Cambridge, UK | Contract Services |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| TauTaTis | , | Shut down 2011 |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Affivant | , | Part of Roivant |
| ADispell | , | Website gone Apr 2018 |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Generex Biotechnology | , | Website gone Feb 2024 |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| Ambion | , | Bought by Applied Biosystems 2006 |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| , | Website down Oct 2025 - Feb 2026 | |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Catalyst Clinical Research | Wilmington , NC | Clinical research solutions to the global biopharmaceutical industry |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| Bayer | Barcelona, Spain | Small Molecules |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| , | ||
| , | Website down Jun 2025 - Dec 2025 | |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| GIPAM | Wismar, Germany | Market Access Consulting |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| Partner Therapeutics | Lexington, MA | Biologics |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Northern Lipids | , | Renamed Transferra |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| SCOLR Pharma | , | Closed Mar 2013 |
| Diagast | Loos, France | Transfusion Reagents |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| , | Website down Sep 2025 - Dec 2025 | |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| Libra Clinical Research Associates | , | Gone |
| Helsinn | Lugano, Switzerland | Small Molecules |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Gerard Biotech | , | Lab supplies, seems defunct |
| SmartCells | , | Bought by Merck Dec 2010 |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| Attogene | Austin, TX | Rapid Diagnostics |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| AdvaStim | , | Shut down, Dec 2017 |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Abselion | Cambridge, UK | Biologics Quantification |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| MiRus | Marietta, GA | Spine Implants |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| Clear Image Technology | , | Now CIT Ortho |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| CovX Research | , | Bought by Pfizer |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| , | Website taken over Nov 2025 - Mar 2026 | |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Neurophet | Seoul, Korea | AI-Image Processing |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Lupin | Baltimore, MD | Generics |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Davol | , | Acquired by Bard, 1980 |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| ResMed | San Diego, CA | Medical Devices |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| Celsis | , | Now AAIPharma |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| Spherics | , | Bankrupt |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| XStalBio | , | Folded |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| , | Website down Dec 2025 - Apr 2026 | |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| Turku Bioscience | Turku, Finland | Research Services |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| CMD Medtech | Columbus, OH | Medical Device Development |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| THORASYS | Montréal, QC | Lung Function Measurement |
| , | Renamed PsiThera, Dec 2025 | |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| Saniona | Glostrup, Denmark | Small Molecules |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| Brighton Biotech | , | Only employee is an accountant |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| Tasso | Seattle, WA | Blood-collection products |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| , | Acquired by IQVIA | |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| Innovagen | Lund, Sweden | Custom antibody development |
| FIT Biotech | , | Bankrupt Feb 2019 |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Novacea | , | Bought by Transcept |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| , | Acquired by Xoma, Sep 2025 | |
| PharmedArtis | , | Gone 2019 |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| Lavipharm | Peania, Greece | Small molecules |
| Guangzhou, China | Clinical Research | |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| SelectX | , | Website hacked; No updates since 2011 |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Provasculon | , | Website Gone, Apr 2014 |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Metrad Biosystems | , | Website gone |
| Synedgen | Claremont, CA | Biofilm Control |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Apcer Life Sciences | London, UK | Consultants |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| Stemnovate | Cambridge, UK | Research Cells |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Tella | , | Website down May 2023 - Dec 2023 |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Helus Pharma | Toronto, ON | Psychedelics |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| Senseonics | Germantown, MD | Medical Devices |
| DoveTree Medicines | , | |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| CombImmune | , | Website Gone Jul 2015 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Panacos | , | Believe they are inactive |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| Genencor | , | Bought by DuPont |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Arcellx | Rockville, MD | Adaptive Immune Cell Therapies |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Chanelle Pharma | Amman, Jordan | Generics |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Amadix | Valladolid, Spain | Diagnostic development |
| BioVolutions | , | Gone |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| Oxehealth | , | Pivoted to mental health platform |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| ViraCyte | , | Renamed AlloVir |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| Nucleus Network | Herston, Australia | Clinical Research |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| MediQuest Therapeutics | , | Gone? |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Orros Therapeutics | , | gone 2018 |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| , | Part of Genesis Biotechnology Group | |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Gastrotech | , | Now Rose Pharma |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| numares | Regensburg, Germany | Clinical Diagnostics |
| , | Merged with Cohance, May 2025 | |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Premier Biomedical | , | Pivoted out of life science |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| , | Website down Jan 2026 - May 2026 | |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| Genuine Biosystem | Chennai, India | IVD Products |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Accellacare | Winston-Salem, NC | Clinical Research |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Alera Labs | Durham, NC | Contract Research & Services |
| Gamma Therapeutics | , | Gone |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| BioWa | , | Part of Kyowa Kirin Group |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| NeuTec Pharma | , | Shut down 2010 |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Pivotal BioSciences | , | Shut down late 2018 |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| AddBIO | , | Gone Oct 2023 |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Allergenics Inc | , | Closed Mar 2007 |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| Boston Scientific | Galway, Ireland | Medical Devices |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| Western States Biopharmaceuticals | , | Website Taken Over |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Cyberval | , | Seems inactive Feb 2024 |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| GSK | Hamilton, MT | Vaccine additive |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| ArunA Biomedical | , | |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Best Vascular | , | Now Best Vascular Novoste |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Omneuron | , | Closed |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| Criterium | Saratoga Springs, NY | Clinical Research |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| AbBaltis | Kent, UK | Plasmas & Sera |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| , | Main employees gone for months as of Nov 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Proteintech | Wuhan, China | Research Antibodies |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Samsara Sciences | , | Shut Down Mar 2020 |
| |
Mississauga, ON | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| NeuMed | , | Website four years since update, no employees on LI |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Proteologics | , | Apparently Gone |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Best Vascular Novoste | , | Now Novoste |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| TcLand Expression | , | Website Gone |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Prommune | , | |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| Angioslide | , | Gone, Oct 2009 |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| Biological Dynamics | , | Shut down Jul 2024 |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| Tuevol Therapeutics | , | Gone by 2020 |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| , | Website down Sep 2025 - Feb 2026 | |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Sure Genomics | , | Gone 2014? |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Birdotech | Shanghai, China | CDRMO |
| Encorium | , | Bankrupt |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| AdrenaCard | , | Gone 2019 |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| , | Acquired by MMS, Feb 2025 | |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| , | Website down Sep 2025 - Feb 2026 | |
| , | Renamed THX Pharma, Sep 2025 | |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| , | Renamed Imviva Biotech, Oct 2025 | |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| Genomics PLC | Oxford, UK | Genomic algorithms |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| NorthLinks Bio | , | |
| TocopheRx | , | Gone before 2019 |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| preclinics | Potsdam, Germany | Contract Research |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| NeuroSearch | , | Wound down 2012 |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Trine Pharmaceuticals | , | Closed 2008 |
| KeraCure | , | Gone 2014 |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| Envisagenics | New York, NY | Software-based drug discovery |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| NeuralInk | Fremont, CA | Neural Implants |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Innogenix | Amityville, NY | Generics |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| QInstruments | Jena, Germany | Lab Instruments |
| Vivamer | , | Shut down, Jul 2015 |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| GenSure | Shijiazhuang, China | Diagnostics |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| , | Website down Oct 2025 - Feb 2026 | |
| Pfizer | Ringaskiddy, Ireland | API production |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Invenra | Madison, WI | Antibodies and their derivatives |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| 206 Ortho | , | Shut down 2021 |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| TumorGen | San Diego, CA | Cancer Treatments |
| NeurAegis | , | Seems gone, Sep 2022 |
| NextPharma | Limay, France | Contract Research & Development |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| Ergomed | Madrid, Spain | Clinical Research |
| alphaSyx Therapeutics | , | Gone |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Gossamer Bio | San Diego, CA | Small Molecules |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Taligen Therapeutics | , | Acquired by Alexion |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| AndroBioSys | , | Presumed gone |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| , | No news 2016 - Sep 2025 | |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| , | Shut down Apr 2026 | |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Medtronic | Minneapolis, MN | Medical Devices |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| Catalyst Clinical Research | Cheshire, UK | Clinical research solutions to the global biopharmaceutical industry |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| , | ||
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Asensus Surgical | Durham, NC | Robot surgical system |
| Velquest | , | Bought by Accelrys Jan 2012 |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| Genae Associates | , | Acquired by IQVIA |
| Viwit | Shanghai, China | APIs, Formulation |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Apieron | , | Shut down, May 2010 |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| , | Website down Jul 2025 - Dec 2025 | |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Immunovaccine | , | Rebranded IMV, 2018 |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| LKC Technologies | Gaithersburg, MD | Electrophysiology Systems |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Chroma Medicine | , | |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| , | Website down Sep 2025 - Feb 2026 | |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Solexa | , | Merged with Illumina 2006 |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| Novonesis | Bangalore, India | Enzymes |
| , | Acquired by Instem, Jul 2025 | |
| Alizyme | , | Bankrupt 2009 |
| , | Website down Jan 2026 - May 2026 | |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Metronomia | Munich, Germany | Consulting & Data Management |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Pharmaron | Ningbo, China | R&D Services |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Eurand | , | Now Aptalis |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Vitrology | , | Acquired by SGS, May 2012 |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| , | Acquired by IQVIA | |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| Biohit | Helsinki, Finland | Diagnostics |
| Getinge | Ankara, Turkey | Medical Technology |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Immutics | , | Renamed TrueBinding |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| Novosis | , | Acquired by Acino, 2006 |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| Arraystar | Rockville, MD | Microarrays |
| Metabasis | , | Bought by Ligand |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Rhythm Health | , | Renamed Motus Therapeutics |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| , | Renamed Turing Medical | |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Dornier MedTech | Sillingy, France | Urology Devices |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Genedata | Basel, Switzerland | Bioinformatics |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| La Jolla Biologics | , | Website gone Nov 2014 |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| AxoTect | , | Phantom company |
| TCXpress | , | Renamed BlueSphere Bio |
| , | Acquired by Generic Specialties, May 2016 | |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Menarini | Firenze, Italy | Small Molecules |
| Talee Bio | , | Renamed Spirovant Sciences |
| , | Website down Oct 2025 - Feb 2026 | |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| Eleven P15 | , | Shut down |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Atanse | , | Website gone, May 2018 |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Angiomics | , | Product being sold by another company |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Regulaxis | , | No news 2020-2024 |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Biotheneum | , | Gone |
| , | Website down May 2025 - Dec 2025 | |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| E3X Bio | , | Shut Down Mar 2019 |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Cymbiotics | , | Gone 2019-2020 |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| Platelet BioGenesis | , | renamed PlateletBio |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| United Neuroscience | , | Renamed Vaxxinity |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| GlySens | , | Bankrupt Nov 2022 |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Ameridose | , | Shut Down 2012 |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| , | Website down Jul 2025 - Jan 2026 | |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Narus Development Solutions | , | Gone |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Abgent | , | Renamed Abcepta, 2019 |
| , | Website down Jul 2025 - Jan 2026 | |
| Inventprise | Redmond, WA | Vaccines |
| Neurotronik | , | Most employees moved to InnerPulse |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| Biopar | , | Gone? |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| American Drug Co. | , | Renamed Five Star Products |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Novotech | Hong Kong, China | Clinical Research |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Doer Biologics | Hangzhou, China | Biologics |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| Akkadix | , | Gone 2001 |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| superDimension | , | Acquired by Covidien May 2012 |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| , | Pivoted to defense contracting, Jan 2026 | |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| , | Website down Jan 2026 - Mar 2026 | |
| Polytherapeutics | , | Gone Jun 2018 |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Avaxia Biologics | , | IP acquired by Circle33 |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| Empatica | Milan, Italy | Seizure Detection |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| D-Pharm | , | Website Gone, Aug 2016 |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| CSL Behring | King of Prussia, PA | Biologics |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| SereDigm | , | Gone Nov 2009 |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| MJ Biopharma | Mumbai, India | Generics |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| CMP Pharma | Farmville, NC | Small Molecules |
| Arbovax | , | Gone |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| Transave | , | Merged with Insmed Dec 2010 |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| , | Website down Jun 2025 - Dec 2025 | |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| DxTech | , | Seems gone. No info Dec 2015 |
| ERBC | Baugy, France | Non clinical CRO |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| , | Acquired by Affluent Medical, Feb 2026 | |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| InnoCare | Shanghai, China | Cancer Treatments |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Paige | New York, NY | AI Pathology |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| Sanofi | Reading, UK | Small Molecules |
| Neurologix | , | Bankrupt, Liquidation |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Human Genome Sciences | , | Bought by GSK |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| Newgen Biopharma | , | Suspended trading due to scandal |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| , | Acquired by Sensei Biotherapeutics, Feb 2026 | |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Veeva Systems | Dublin, OH | Life Science Software |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Proxygen | Vienna, Austria | Cancer Therapies |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Globe Life Sciences | London, UK | Strategy Consulting |
| PeriGen | Cary, NC | Perinatal Devices |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Zephyr AI | McLean, VA | AI Data Analysis |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| Lifebit | London, UK | Genetic Data Analysis |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Scios | , | Bought by JnJ, Feb 2003 |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| NuVascular Technologies | , | Shut down Nov 2021 |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| , | Acquired by QOL Medical, Nov 2025 | |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Arete Therapeutics | , | Out of Business |
| Dalex Biotech | , | Gone |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| MicroPort | Arlington, TN | Medical Devices |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| AccelaPure | , | Bankrupt 2007 |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Anchen | , | Bought by Par Pharmaceutical |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Apaxis Medical | , | Gone 2019 |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| Elektrofi | Boston, MA | Biologics Formulation |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| 121 Bio | , | Gone mid 2016 |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| Tanai Therapeutics | , | Obesity Treatment |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| Coral Drugs | New Delhi, India | APIs |
| SphynKx Therapeutics | , | Gone |
| Natera | San Carlos, CA | Prenatal Testing |
| Curia | Albany, NY | Contract Research, Development, Manufacturing |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Novasecta | London, UK | Pharma Consultancy |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Phenomyx | , | Gone Jun 2019 |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| CombinatoRx | , | Now Zalicus |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| ProPharma Group | Bozeman, MT | Consulting |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Cambrian Bio | New York, NY | Small Molecules |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| , | Part of Normec | |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| Compliment Corporation | , | Closed Dec 2011 |
| Alfacell | , | Now Tamir Biotechnology |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Agrisera | Vännäs, Sweden | Antibodies |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| Cytiva | Piscataway, NJ | Medical Devices |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| Gilead | Foster City, CA | Small Molecules |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Mitokyne | , | Renamed Mitobridge |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| , | Acquired by Altaris, Mar 2025 | |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Alkermes | Wilmington, OH | Small Molecules |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| Quanticate | Raleigh, NC | Clinical Research |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| ErVimmune | Lyon, France | Cancer Vaccines |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| |
Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| Integer | Salem, VA | Medical & Surgical Devices |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Instylla | Bedford, MA | Embolization treatment |
| ChunLab | , | Renamed CJ Bioscience |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Genecare | , | Gone |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Medispect | , | Shut Down 2013 |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| GT Biologics | , | Renamed 4D Pharma Research |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| Genyous Biomedical International | , | Presumed Gone |
| Cam Med | , | Renamed Qlibrium |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| tiakis Biotech | Kiel, Germany | Biologics |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Gencove | New York, NY | Genome Sequencing |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| Delpharm | Huningue, France | Contract Manufacturing |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| PeriCor Therapeutics | , | Website Gone |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| BGI | Kobe, Japan | Genetic Testing |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| Vali Nanomedical | , | Gone 2016 |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| August Therapeutics | , | Shut down Dec 2024 |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| , | Renamed Virchow | |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Clinical Microbiomics | , | Merged into cmbio |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Boston Scientific | Marlborough, MA | Medical Devices |
| , | Website down Sep 2025 - Feb 2026 | |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| Keenova | Malvern, PA | Small Molecules |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Sterling | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Syneos Health | Morrisville, NC | Clinical Development |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Daktari Diagnostics | , | Gone 2017 |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Aixlie Pharmaceuticals | , | No idea what happened |
| Cairn Research | Kent, UK | Scientific Instruments |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| , | Shut down Oct 2023 | |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Nuventra Pharma Sciences | , | Now Allucent |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Evozyne | Chicago, IL | Protein Design Platform |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| Aimmune Therapeutics | , | |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Sea Medical Systems | , | Gone |
| Biotia | Brooklyn, NY | AI Genomics |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Modular Medical | San Diego, CA | Insulin Pump |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| TheraCoat | , | Renamed UroGen Pharma |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Vaccibody | , | Renamed Nykode Therapeutics |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Ossur | Irvine, CA | Orthopedic Devices |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| SYNCROSOME | Marseille, France | Preclinical contract research |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| neoSurgical | , | Shut down 2017 |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| Tapestry Pharmaceuticals | , | Gone |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| LumaBridge | San Antonio, TX | Clinical Research |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| Ocis Biotechnology | , | |
| MSD | Dublin, Ireland | Women's Health Products |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| Triangle Insights Group | Durham, NC | Consulting |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Advarra | Columbia, MD | Regulatory Consulting |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| Pharsight | , | Merged with Tripos to become Certara |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Alchemgen | , | Gone |
| EPD Biotherapeutics | , | |
| Protein Metrics | Boston, MA | Protein characterization software |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| TruGenomix | , | Renamed Polaris Genomics |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Altasciences | Montréal, QC | Contract Research |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Ekteino | , | Closed, Dec 2016 |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Creative Enzymes | Shirley, NY | Enzymes |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Semafore Pharmaceuticals | , | Gone? |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| MicroVention | , | Now Terumo Neuro |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| BIND Biosciences | , | Now BIND Therapeutics |
| QSV Biologics | , | Website Gone |
| Gensignia | , | Website Gone, Aug 2017 |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Novo Nordisk | Beijing, China | Inflammation Research |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Lupin | Coral Springs, FL | Generics |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| , | Website down Jan 2026 - May 2026 | |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Novotech | Auckland , New Zealand | Clinical Research |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Xention | , | All programs halted or disposed of by 2016 |
| , | Website down Dec 2025 - Mar 2026 | |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| |
Bethlehem, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| , | Website 404 Sep 2025 - Apr 2026 | |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| iCareDx | , | Renamed AcuamarkDx |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Bruker | Billerica, MA | Scientific Instruments |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| ABgene | , | Bought by Apogent, Dec 2001 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| Clinnex | Ahmedabad, India | Clinical Research |
| Crystal Bio Solutions | Cranbury, NJ | Bioanalytical services, biomarker discovery, CMC analytical services, and quantitative clinical pharmacology |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| CRI | , | Now BiomericsATL |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| StemCell2MAX | , | Website gone Apr 2019 |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Prominex | San Diego, CA | POC Diagnostics |
| NantCell | , | Renamed ImmunityBio |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| Sanofi | Frankfurt, Germany | Small Molecules |
| , | Website down May 2025 - Dec 2025 | |
| Boston Scientific | Cork, Ireland | Medical Devices |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Bionsight | Seoul, Korea | Database For Research |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| Java Clinical | , | Website gone Jun 2019 |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Infinitopes | Oxford, UK | Vaccines |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| Maccine | , | Gone |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| Stryker | Portage, MI | Medical Devices |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Raze Therapeutics | , | Closed due to complicated biology |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| , | Acquired by Medicover, Apr 2026 | |
| Cell Technology | , | Acquired by ICT |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Axplora | Raubling, Germany | API CDMO |
| PPL Therapeutics | , | Sold in 2003 |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Biorelate | Manchester, UK | AI Data Curation |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| , | Website taken over, Nov 2025 | |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Zai Lab | Hong Kong, China | Small Molecules |
| CFL Biotech | , | Website gone Jul 2020 |
| , | Merged into Meridian Bioscience | |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Neurogene | New York, NY | Genetic Therapies |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| , | Acquire by Savillex, Nov 2024 | |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Norgine | Madrid, Spain | Specialty Pharma |
| M3 Wake Research | Encino, CA | Clinical Research |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| Berg Pharma | , | Now just Berg |
| Alife | San Francisco, CA | AI-powered IVF |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Erbe | Tübingen , Germany | Surgical Systems |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Genialis | Boston, MA | Bioinformatics |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Picoseq | , | Renamed Depixus |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Macrogen | , | Renamed Psomagen, 2019 |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| Organon (2) | Jersey City, NJ | Women's Health |
| Torrington, CT | Animal Research Equipment | |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| , | Website down Nov 2025 - Apr 2026 | |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Glide Pharma | , | Renamed Glide Technologies |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Action Pharma | , | Abbott acquired product, 2012 |
| AstraZeneca | Baar, Switzerland | Biologics |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| GenQual | , | Inactive, Jun 2017 |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| Barc Lab | , | Renamed Cerba Research |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Amplyus | , | Renamed miniPCR |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| AerovectRx | , | No news since 2006, Website gone |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| Hologic | Newark, DE | Diagnostic, Imaging |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Curia | Frankfurt, Germany | Contract Development, Manufacturing |
| LENSAR | Orlando, FL | Cataract Laser |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Curia | Rensselaer, NY | Contract Research, Development, Manufacturing |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| ResearchDx | Irvine, CA | Diagnostics |
| , | No news 2021 - Jan 2026 | |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| Steris | Mentor, OH | Contamination Control |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| icometrix | Leuven, Belgium | Imaging AI |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| QT Vascular | , | Website gone Jan 2024 |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| tte laboratories | , | Acquired by Transcat |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Flownamics | Madison, WI | Automated Sampling |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Cell Targeting Inc | , | Bought by Biotime |
| Cherry Biotech | Paris, France | Organoid Culture |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| SK Biotek | , | part of SK pharmteco |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| , | Acquired by Frontage, Jul 2021 | |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| DiAthegen | , | Website Gone Oct 2015 |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| , | Website down Dec 2025 - Apr 2026 | |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| Northfield Laboratories | , | Bankrupt 2009 |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| Octapharma | Stockholm, Sweden | Plasma Products |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Neose | , | Gone |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| PulmoGeniX | , | No business filings 2016-2020 |
| Synergen | , | Bought by Amgen 1994 |
| Nymirum | , | Renamed Base4, Feb 2023 |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| , | Website down Nov 2025 - Apr 2026 | |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Niowave | Lansing, MI | Radioisotopes |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| VasoNova | , | Acquired by Teleflex Medical |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| ActivaTek | , | Acquired by North Coast Medical |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| Derma-Cell Research | , | Website gone Nov 2019 |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| Bionas Discovery | , | Website gone Jun 2018 |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Facet Biotech | , | Bought by Abbott 2010 |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Moleac | Singapore, Singapore | Stroke Products |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Neuro Bio | Oxford, UK | T14 Blocker |
| DNAMx | , | Renamed Adela |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Yposkesi | , | part of SK pharmteco |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Antibiotice | Iasi, Romania | Generics |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| Getinge | Solna, Sweden | Medical Technology |
| AmProtein | , | Presumed Gone |
| Tgen Tech | , | Renamed Annoviant |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| BioClinical Solutions | Chicago, IL | Clinical Trial Solutions |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| Alcon | Irvine, CA | Eye-Care Products |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Tico Bio | , | Renamed Inso Biosciences |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| R2M Pharma | South SF, CA | Drug Development Services |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| , | Website down Sep 2025 - Dec 2025 | |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| QuatRx | , | Acquired by Shionogi, 2017 |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| Quantamerix | , | No info since 2012, never registered in MA |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| Trimeris | , | Merged with Synageva |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Synlab | Munich, Germany | Clinical Lab Services |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| DFE Pharma | Goch, Germany | Excipients |
| Axya medical | , | Gone 2012 |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| NeuroVasx | , | No website May 2019, founded 1997 |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| , | Renamed Ladder Bio, Nov 2025 | |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| , | Website down Dec 2025 - Apr 2026 | |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| iLeadBMS | Gyeonggi, Korea | Small Molecules |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| Eisai | Nutley , NJ | Small Molecules |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| |
Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Curis | Lexington, MA | Small Molecules |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Cellanome | Foster City, CA | Multiomics Platform |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Kate Therapeutics | , | |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Healionics | Seattle, WA | Biomaterials for devices |
| Vericel | Ann Arbor, MI | Cellular Products |
| Michigan Clinical Research Institute | , | |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| , | Pivoted to crypto Jan 2026 | |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| Mendaera | San Mateo, CA | Medical Robotics |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| , | No news Mar 2021 - Jan 2026 | |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Pall | Port Washington, NY | Filtration |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| JAJ International | , | Website not working, redirecting strangely |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| Sitka Biopharma | , | Website gone Jan 2022 |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| Sebia | Lisses, France | Electrophoresis |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| Genova Clinical Research | , | Gone, 2014 |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| ReSync Bio | , | Acquired by Benchling 2025 |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Precision Virologics | , | Precision Virologics |
| , | Website down Sep 2025 - Dec 2025 | |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Parabase Genomics | , | Presumed gone |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Viropro | , | Bankrupt 2015 |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Cirina | , | Merged with Grail, May 2017 |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| Cala Health | San Mateo, CA | Neurological Device |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| , | Website down May 2025 - Nov 2025 | |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Pathfinder Cell Therapy | , | Gone 2016 |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| 2 Bridge | Zoersel, Belgium | Consulting |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| PepVax | , | Gone 2024 |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Minntech | , | Now Medivators |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| Ergomed | Frankfurt, Germany | Clinical Research |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Solace Therapeutics | , | Shut down Sep 2022 |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Cerimon | , | Gone |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| NeurAxon | , | No updates since 2008 |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Ventris Medical | Newport Beach, CA | Tissues |
| Acelyrin | , | Merged into Alumis, May 2025 |
| Qrativ | , | Folded into nFerence |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| Suvoda | Portland, OR | Clinical Trial Software |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| MSN Labs | Hyderabad, India | Generics |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Madison Vaccines | , | Website gone Dec 2019 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Sensys Medical | , | Old company, no website, presumed defunct |
| , | Website down Sep 2025 - Dec 2025 | |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| Snorx | , | Renamed Zelegent, May 2015 |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| , | Shut down Jan 2024 | |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| , | Shut down Jan 2024 | |
| AJES Life Sciences | , | Renamed L2P Research |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| Vivacy | Archamps, France | Aesthetic Medicine |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| , | Website down Jan 2026 - May 2026 | |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| BiOM | , | Now BionX Medical |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| , | Acquired by Xoma, Oct 2025 | |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| CeNeRx | , | Shut Down, 2013 |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| MedShape | , | Acquired by DJO, Apr 2021 |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Conkwest | , | Website gone Dec 2015 |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| , | Acquired by Arterex, Jun 2023 | |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| ProteinLinks | , | Seem gone |
| Altravax | , | Shut down 2016 |
| Curia | Hyderabad, India | Contract Research |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| Quiescence Technologies | , | Website Gone |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| Aerovance | , | Gone, don’t know where |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| Ascend Genomics | , | Shut down |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| BioMap | Palo Alto, CA | AI Models |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Domainex | Essex, UK | Drug Discovery Services |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Beacle | , | Founder gone, no info |
| ZyStor | , | Bought by BioMarin, closed |
| Actium Biosystems | , | Gone 2013 |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| Sundia | , | Part of BioDuro |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Blackfynn | , | Gone Apr 2022 |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| , | Renamed First Atom Therapeutics | |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| , | Website down Jul 2025 - Dec 2025 | |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| Bio-Processing Alliance | , | Website now for a training company |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Syngene International | Bangalore, India | Contract Research |
| MicroCam | , | Shut down 2015? |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| Oligasis | , | Changed named to Kodiak Sciences |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| bespark*bio | Vienna, Austria | Consulting |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Aspira Labs | , | Renamed Aspira Women's Health |
| ECI Biotech | , | Gone 2016 |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| , | No news Aug 2019 - Jan 2026 | |
| Delpor | Brisbane, CA | Drug Delivery System |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| iCeutica | , | Seems gone, Jan 2022 |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| , | ||
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Horiba Instruments | Irvine, CA | Equipment |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Paris, France | Molecular Discovery Platform | |
| Scion Medical Technologies | , | Gone 2016 |
| NeoVista | , | Gone 2011 |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Akesis LLC | , | Bankrupt 2015 |
| Michrom | , | Bought by Bruker, Feb 2011 |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| BaseCure Therapeutics | , | |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Velomedix | , | Shut down 2014 |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Anumana | Cambridge, MA | AI ECG reading |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| , | Website down Sep 2025 - Feb 2026 | |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| ConjuChem | , | Bankrupt 2011 |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Convalife Pharmaceuticals | Shanghai, China | Oncology, viruses and aging treatments; bispecific antibodies, small molecules |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| PharmaVigilant | , | Gone 2014 |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Signatur Biosciences | London, UK | PCR Platform |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Stasys Medical | , | Shut down Feb 2025 |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| Affinimark Technologies | , | Gone |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| CONMED | Utica, NY | Surgical, Medical Devices |
| VM Discovery | , | 20 yr old company with no info on website |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| Mederi Therapeutics | , | Now Mederi-RF |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Neotech | , | Website down Jan 2019 |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Refined Diagnostics | Münster, Germany | Lasers |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| EQL Pharma | Lund, Sweden | Generics |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Curio Bioscience | Palo Alto, CA | High Resolution Spatial Biology |
| Precise Bio | , | Gone 2023 |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Pathway Genomics | , | Renamed OmeCare |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| NeoCura | Beijing, China | Personalized Vaccines |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| , | Renamed Silthera, Apr 2026 | |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Neuroservices-Alliance | Bordeaux, France | Contract Research Organization |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Xenikos | , | Shut down early 2023 |
| Stago | Marseille, France | Diagnostics |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| , | Shut down Jan 2025 | |
| Tethys Bioscience | , | Shut Down, late 2013 |
| Weatherwax | , | Renamed General Proximity |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Glenmark | Monroe, NC | Generic Small Molecules |
| |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Quratis | Cheongju, Korea | Vaccines |
| Alper Biotechnology | , | Gone |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Bastion Therapeutics | , | Shut down |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| bioMerieux | Cambridge, MA | Diagnostics |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| IBA Analytics | , | Website gone Jul 2015 |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| Quantificare | Biot, France | Medical Imaging |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| AmCell Biosciences | , | Website gone Apr 2021 |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Medtronic | Warsaw, IN | Medical Devices |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| MSM Protein Technologies | , | Gone Jun 2019 |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| DLK Medical Technologies | Dallas, TX | OTC |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Stago | Clarkston, GA | Diagnostics |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Celtaxsys | , | No longer active, Aug 2020 |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Ankon Technologies | Wuhan, China | Medical Devices |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| Scintillant Bioscience | , | Gone May 2025 |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| EXO Biologics | Liège, Belgium | Exosomes |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| LianBio | , | Winding down Feb 2024 |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| Antara Biosciences | , | Bankrupt 2007 |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Y's Therapeutics | , | Website Gone |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Accumed Systems | , | Dated website, cant find any employees |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| , | Website down Sep 2025 - Dec 2025 | |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Inference | Pune, India | Clinical Trial Services |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| Quartet Medicine | , | Wound down, Nov 2017 |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| Vessel Biosciences | , | Shut down Mar 2023 |
| Arxspan | , | Renamed SciY |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| SuraMedical | , | Most employees left, not registered in MN |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Anergix | , | Shut down Mar 2009 |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Pathwork Diagnostics | , | Closed 2013 |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| DDL | Irvine, CA | Device Testing |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| iTherapeutics | , | Doubt they do anything |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Zyomyx | , | Closed as of 2014 |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| PL Developments | , | Parts of website taken over |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Ennov | Paris, France | Software Solutions |
| Humanyx | , | No website, Seems gone |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Fusion Biopharma | , | Presumed gone |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Vasade Biosciences | , | Gone |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Renamed Transcend, Feb 2022 | |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| Abbott | Clonmel, Ireland | Stents |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Piramal | Riverview, MI | CDMO |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |