Taiwan - Biotech Companies - Career Pages
| Brain Vision | Morrisville, NC | EEG Systems |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| GeneAssess | , | Gone |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Bioptimus | Paris, France | AI Drug Discovery |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Sanofi | Paris, France | Small Molecules |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| Coordination Therapeutics | , | Not Active |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Angelica Therapeutics | , | Gone 2018 |
| BioMAS | , | Ceased operating, Jul 2016 |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| GSL Biotech | , | Acquired by Dotmatics |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Purdue Pharma | Wilson, NC | Small Molecules |
| Accellacare | Raleigh, NC | Clinical Research |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| amcure | , | Liquidated Sep 2024 |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Inventa Biosciences | , | Not Active |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Steris | Mentor, OH | Contamination Control |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| , | Acquired by Xoma, Nov 2025 | |
| Vascular Technology | Nashua, NH | Surgical Devices |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| Wheaton | , | Renamed DWK Life Sciences |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| VM Discovery | , | 20 yr old company with no info on website |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| Mediso | Budapest, Hungary | Medical Imaging |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| Camurus | Lund, Sweden | Specialty medicines |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
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Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| Ganymede | Palo Alto, CA | Lab Automation |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Pivotal BioSciences | , | Shut down late 2018 |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| TamRx | , | Website taken over Aug 2020 |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| ARC Medical | , | Acquired by Typenex Medical |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| Neocis | Miami, FL | Dental Surgery Robots |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Best Vascular Novoste | , | Now Novoste |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| , | Renamed Benthic Genomics, Sep 2025 | |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| Cell Therapy Ltd | , | Renamed Celixir |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| AzurRx | , | Merged into First Wave Bio |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
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Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| RSSL | Reading, UK | Analytical Services |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| InCytu | , | Website gone Jul 2015 |
| Aliri | Loos, France | Contract Mass Spec |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Enovalife | Paris, France | Biometrics and medical writing services |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| Taxolog | , | Website gone, Nov 2015 |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Epigene Labs | Paris, France | Data Integration Platform |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| iBio | San Diego, CA | Antibody Therapies |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| numares | Regensburg, Germany | Clinical Diagnostics |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| , | Website down Dec 2025 - Apr 2026 | |
| IGF Oncology | , | Shut down 2022 |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| Arkios Biodevelopment | , | Business registration canceled in VA |
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Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| DNAtrix | , | Gone late 2023 |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| Purinomia Biotech | , | |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| , | Website down Aug 2025 - Jan 2026 | |
| , | Website gone Feb 2026 - Apr 2026 | |
| AbbVie | Dublin, Ireland | Medical Devices |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| SK Biotek | , | part of SK pharmteco |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Nuevolution | , | Bought by Amgen May 2019 |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Xcede Technologies | , | Gone Jun 2020 |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Omeros | Seattle, WA | Small Molecules |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| Cure Foreward | , | Services suspended, May 2017 |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Axplora | Chennai, India | API manufacturing |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
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Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| Regenerative Sciences | , | Took on Regenexx product name |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| MMI Genomics | , | Assets bought by Neogen |
| Diploid Genomics | , | |
| Newormics | , | Renamed vivoVerse, late 2022 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Amp Orthopedics | , | Shut down, 2012 |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| Biowarn | , | Gone |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| Ameridose | , | Shut Down 2012 |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| , | Filings late Jun 2025 | |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Weatherwax | , | Renamed General Proximity |
| Adlyfe | , | Gone, no info |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Accellacare | Salisbury, NC | Clinical Research |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Bioxene | , | Website gone, Company Presumed gone |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| NeurOptics | Irvine, CA | Pupillometry |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| Cydan Development | , | Shut down Sep 2021 |
| NsGene | , | Website gone |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Zai Lab | Cambridge, MA | Small Molecules |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| MSM Protein Technologies | , | Gone Jun 2019 |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Pathway Genomics | , | Renamed OmeCare |
| , | Renamed Edding, Feb 2026 | |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Cedilla Therapeutics | , | Shut down May 2023 |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Biorelate | Manchester, UK | AI Data Curation |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Tecomet | Wilmington, MA | Implant Components |
| Stemnovate | Cambridge, UK | Research Cells |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| , | Shutdown Oct 2025 | |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| EuBiologics | Seoul, Korea | Vaccines |
| Light Sciences Oncology | , | Shut down late 2020 |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| Ablacon | , | Shut down Mar 2024 |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Stada | Bad Vilbel, Germany | Generics |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| Conceptus | , | Bought by Bayer Apr 2013 |
| VB Spine | Leesburg, VA | Spinal Implants |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| Zai Lab | South SF, CA | Small Molecules |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Novonesis | Paraná, Brazil | Enzymes |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Cellanome | Foster City, CA | Multiomics Platform |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Birdotech | Shanghai, China | CDRMO |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| NovaDel Pharma | , | Business dissolved 2014 |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| , | Shut down Jan 2025 | |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| QT Vascular | , | Website gone Jan 2024 |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Kirax | , | Website Gone |
| Novonesis | Bangalore, India | Enzymes |
| Nexus Genomics | , | Gone 2001 |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Nanosonics | Manchester, UK | Ultrasound |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
 |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Adlon Therapeutics | , | |
| Sanofi | Frankfurt, Germany | Small Molecules |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| , | Website down Jun 2025 - Dec 2025 | |
| Gene Labs | , | Bought by GSk 2008 |
| SoftGenetics | State College, PA | Software for genetic analysis |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| Dey LP | , | Bought by Mylan 2007 |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Central Pharma | Bedford, UK | Filling, Packaging |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Xtuit | , | Gone Jul 2018 |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| , | Website down Nov 2025 - Apr 2026 | |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Biosion | Nanjing, China | Bispecific Antibody |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| ProCrysta Biologix | , | Shut down 2018 |
| SL Pharma Labs | , | Website gone May 2018 |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Medpace | Cincinnati, OH | Clinical Research |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
 |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Visitube | , | No website Mar 2020 |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Lumanity | London, UK | Consulting |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| , | Website taken over Feb 2026 | |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Sysmex | Tokyo, Japan | Diagnostics |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Barc Lab | , | Renamed Cerba Research |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Clearbridge Biomedics | , | Renamed Biolidics |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| Redoxis | Lund, Sweden | Drug development CRO |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| , | Acquired by Insphero, Nov 2025 | |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Aixa Bio | Cambridge, MA | AI genomics |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| , | Acquired by Sun Pharma, May 2025 | |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Serotiny | , | Acquired by J&J, 2023 |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| Bionode | , | Shut down Mar 2024 |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| Five Star Products | , | Liquidated |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| , | Renamed Indero | |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Apotech Consulting | London, UK | Life Science Consulting |
| , | Website down Nov 2025 - Apr 2026 | |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Perlegen | , | No Site |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Immunovaccine | , | Rebranded IMV, 2018 |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Percivia | , | Shut Down 2012 |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Xention | , | All programs halted or disposed of by 2016 |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Quanticate | Bangalore, India | Clinical Research |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
 |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| WiseGene | , | Website gone jan 2020 |
| AB Sciex | , | Renamed Sciex |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| Ally Therapeutics | , | Shut down early 2021 |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Liposonix | , | Bought by Medicis |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Xenikos | , | Shut down early 2023 |
| Abbott | Irving, TX | Devices |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| BridGE Genomics | , | Gone 2022 |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Mederi Therapeutics | , | Now Mederi-RF |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| , | Renamed Helus Pharma, Jan 2026 | |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| Virscio | New Haven, CT | Contract Research & Consulting |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Terumo Medical | Elkton, MD | Medical Devices |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Virtici | Seattle, WA | Product / Company Incubator |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| SARcode | , | Bought by Shire Mar 2013 |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
 |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Anergis | , | Liquidating, Jan 2021 |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Ikotech | , | Closed Dec 2015 |
| Healogix | Doylestown, PA | Consulting |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| Anaheim Clinical Trials | , | Now CenExelACT |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Animas | , | Shut down, Oct 2017 |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
 |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Jan 2026 - May 2026 | |
| Synergistix | Sunrise, FL | CRM software |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Organogenesis | Canton, MA | Biologics |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| , | Acquired by Waters, 2023 | |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| InnoCare | Shanghai, China | Cancer Treatments |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
 |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Luvak Lab | , | Dissolved 2013 |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| NeoVista | , | Gone 2011 |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| Clontech | , | Now Takara Bio |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Saniona | Glostrup, Denmark | Small Molecules |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| StemPar Sciences | , | Website disappeared, no news |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
 |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Gene Logic | , | Bankrupt |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Siga | New York, NY | Small Molecules |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Cytiva | Amersham, UK | Medical Devices |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| Rubix Device | , | Website gone, Aug 2017 |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| Jaleva Pharmaceuticals | , | Gone |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| BioVascular | , | 2007 website as of Mar 2019 |
| Biophytis | Paris, France | Therapies for aging diseases |
| Applied Molecular Genetics | , | Renamed Amgen |
| 7TM Pharma | , | Gone |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
 |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Cytiva | Marlborough, MA | Medical Devices |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Onorach | Dundee, UK | Clinical Trial Management |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Xenomics | , | Now TrovaGene |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| Osteologix | , | Liquidated, Sep 2015 |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| Ergomed | Mumbai, India | Clinical Research |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| CertiRx | , | Shut down |
| Sytera | , | Merged with Sirion Aug 2006 |
| Altair Therapeutics | , | Shut down Feb 2011 |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| Via Pharmaceuticals | , | Shell Company |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
 |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| , | Company gone Nov 2023, website taken by a game | |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| Erba MDX | , | Website gone Aug 2019 |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Vessel Biosciences | , | Shut down Mar 2023 |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Neurokos | , | Gone. No info |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Biological Dynamics | , | Shut down Jul 2024 |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Actome | Freiburg, Germany | Protein Quantification |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Artimplant | , | Bankrupt, 2013 |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| Blackfynn | , | Gone Apr 2022 |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| , | Renamed EarliPoint Health, Oct 2025 | |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| ArKal Medical | , | Gone 2012 |
| , | Acquired by AbbVie, Aug 2025 | |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| Promaxo | Oakland, CA | Small form MRI |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| AlphaGenix | , | Gone 2014 |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| , | Website taken over, Jan 2026 | |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Epic Sciences | , | Shut down May 2025 |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| Protelight Pharmaceuticals | Jiangyin, China | Peptide and Small Molecules Therapies |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| Aytu BioScience | , | now Aytu BioPharma |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| ions.bio | Planegg, Germany | Biomarkers |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| NorthLinks Bio | , | |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Molsid | Lyon, France | Fluorogenic Probes |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Angioslide | , | Gone, Oct 2009 |
| Metris Therapeutics | , | Presumed Gone |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| , | Website down Jan 2026 - May 2026 | |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
 |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| Celtaxsys | , | No longer active, Aug 2020 |
| Putney | , | Acquired by Dechra, Mar 2016 |
| Menarini | Firenze, Italy | Small Molecules |
 |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Cairn Research | Kent, UK | Scientific Instruments |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| MediLink Therapeutics | Suzhou, China | ADC |
| Cenix Biosciences | , | Website gone Jul 2015 |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Valneva | Livingston, UK | Biologics Manufacturing |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| , | Website down Dec 2025 | |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| OverT Bio | New York, NY | Cell Therapy |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Meta-Iq | , | Website gone Jun 2020 |
| Gensignia | , | Website Gone, Aug 2017 |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Opis Research | Desio, Italy | Clinical Research |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| Orexia | , | Acquired by Centessa |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| , | Renamed Alethio Therapeutics | |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| , | Acquired by Bruker, May 2024, €870M | |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Getinge | Mumbai, India | Medical Technology |
| WideCELLS | , | Shut down Nov 2019 |
| Akkadix | , | Gone 2001 |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| , | Website down Jan 2026 - May 2026 | |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Boston Biokeys | , | Gone June 2017 |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Apcer Life Sciences | London, UK | Consultants |
| ImmuneMed | , | Shut Down |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Topivert | , | Liquidating Jan 2021 |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Talis Biomedical | , | |
| ImmuneWorks | , | Website gone, Apr 2018 |
| , | Website down Jul 2025 - Mar 2026 | |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Innogenix | Amityville, NY | Generics |
| Avrin | Liverpool, UK | Clinical Research |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Aimmune Therapeutics | , | |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Morphochem | , | Acquired by Deinove, May 2018 |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| JAJ International | , | Website not working, redirecting strangely |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Virapur | , | Acquired by Microbiologics, 2017 |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Advangen | , | Acquired by Cellmid, May 2013 |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| ArisGen | , | Only employee has four other jobs |
| Nanosonics | Sydney, Australia | Ultrasound |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
 |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Institute for Drug Discovery | , | Gone |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| Journey Colab | , | Shut down Jan 2025 |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| Lupin | Coral Springs, FL | Generics |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| CohBar | , | Shut down, late 2023 |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Epigenos Biosciences | , | |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Accellacare | Wilmington, NC | Clinical Research |
| Santen | Tampere, Finland | Ophthalmics |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| , | Seems renamed to Lusis Biosciences | |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| MindRank | Shanghai, China | AI Drug Discovery |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| Pharmaron | Tianjin, China | R&D Services |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Patrin Pharma | Skokie, IL | Generics |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| PowderMed | , | Acquired by Pfizer 2006 |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Sanofi | Reading, UK | Small Molecules |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Prokarium | London, UK | Oral Vaccines |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| America Stem Cell | , | Changed name to Targazyme |
| Wetlin Research Associates | , | Centerwatch only |
| , | Website down May 2025 - Dec 2025 | |
| KangaBio | Shanghai, China | Multi-specific biologics |
| GMP-Orphan France | , | Renamed Orphalan |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| Exactech | Gainesville, FL | Medical Implants |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Actera Pharmaceuticals | , | Closed |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Protox Therapeutics | , | Now Sophiris Bio |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Trophea | , | Liquidated, Dec 2019 |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| NextGen Sciences | , | Defaulted, sued by employees |
| , | Part of Genesis | |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| British Biotech | , | Merged into Vernalis 2003 |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Acculysis | , | Website gone, sole employee with Agilent now |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Integra LifeSciences | Boston, MA | Medical Devices |
| CatSci | Cardiff, UK | Contract Research |
| , | No news Mar 2021 - Jan 2026 | |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Almac | Souderton, PA | Pharmaceutical Services |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| Pirche | Grünwald, Germany | Transplant Matching |
| Roche | Welwyn, UK | Small Molecules |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Velcura Therapeutics | , | Website Gone |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| Rhythm Health | , | Renamed Motus Therapeutics |
| , | Website taken over Jun 2026 | |
| Hemadvance | , | Gone |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| MabCo | , | Renamed Agenix |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Relion | , | Shut down 2015? |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| REPROMEDIX | , | Gone 2012 |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| Evofem Biosciences | San Diego, CA | Women's health |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Bora Biologics | San Diego, CA | Contract Biologics |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| Cellipse | , | Website taken over May 2020 |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| BioChain | Newark, CA | Sample Preparation |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| GenoSpace | Boston, MA | Platform for genomic data |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| , | No news 2019 - Oct 2025 | |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Zetra Biologicals | , | Gone |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| PhoreMost | Cambridge, UK | Biologics |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Northern Lipids | , | Renamed Transferra |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| Scion NeuroStim | , | Presumed gone |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| , | No news 2019 - Apr 2026 | |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| , | Website down Jul 2025 - Dec 2025 | |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| American Stem Cell | , | Changed name to Targazyme |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Sinovac Biotech | Beijing, China | Vaccines |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| Rallybio | New Haven, CT | Therapeutics |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
 |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Medicure | Princeton, NJ | Small Molecule |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| Piramal | Morpeth, UK | CDMO |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Belyntic | Berlin, Germany | Immunotherapies |
| MedCision | , | Assets bought by MedCision, May 2018 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| , | Website down Aug 2025 - Jan 2026 | |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| Originus | , | Gone |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| TCG GreenChem | Ewing, NJ | |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| Abbott | Sylmar, CA | Device Manufacturing |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Ipsen | Dublin, Ireland | Small Molecules |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| DoveTree Medicines | , | |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Ergomed | Moscow, Russia | Clinical Research |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| MediciNova | La Jolla, CA | Small Molecules |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| CytRx | , | Renamed LadRx Sep 2022 |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| ClearView | Newton, MA | Strategic Consulting |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| Galileo Research | , | No news since 2012, presumed gone |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Cam Med | , | Renamed Qlibrium |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| , | Website down Nov 2025 - Apr 2026 | |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| BioVolutions | , | Gone |
| Applied Integrin Sciences | , | Gone |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Lenire Biosciences | , | Shut down Nov 2023 |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Qynapse | Paris, France | Imaging Analysis |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Cromos Pharma | Portland, OR | Clinical Research |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| CureBiotech | , | Presumed gone |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| SteriTech | Sligo, Ireland | Process Equipment |
| Alchemia | , | Gone, late 2017 |
| Agenix | , | Gone, Website taken over |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| , | Website down May 2025 - Oct 2025 | |
| Roche | Penzberg, Germany | Diagnostics |
| Roowin | Riom, France | Chemical Synthesis |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Kylin Therapeutics | , | Sold |
| Lavipharm | Peania Attica, Greece | Small molecules |
| DC Biosciences | , | Shut down Jul 2023 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| CytoVera | , | Gone June 2017 |
| IQVIA | Durham, NC | Clinical Research |
| , | Seems to be News website, Jan 2026 | |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| , | Website down Dec 2025 - Apr 2026 | |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| VitalMedix | , | Out of Money 2010 |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| ViThera Pharmaceuticals | , | Gone 2017 |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| inDNA Research Labs | , | Shut down 2015 |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Sinusys | , | Shut down 2023 |
| InfraReDx | Bedford , MA | Medical Devices |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| , | Acquired by Alcon, Sep 2025 | |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| 206 Ortho | , | Shut down 2021 |
| ResVerlogiX | Calgary, AB | Small Molecules |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Gran Med | , | Gone |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| NeuTec Pharma | , | Shut down 2010 |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| KALA BIO | Arlington, MA | Drug Delivery |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Physical Sciences | Andover, MA | Retinal Imaging |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| Primera Biosystems | , | Now PrimeraDx |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Novonesis | North Rocks, Australia | Enzymes |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Formulatrix | Bedford, MA | Lab Automation |
| Theranostech | , | Renamed Sandia Biotech |
| Bonenta | , | Website gone |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Unither Pharmaceuticals | Paris, France | CDMO |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| Esoterix | , | Bought by LabCorp, May 2005 |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| Anthra Pharmaceutical | , | Gone |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| Texcell | Gronau, Germany | Contract Research |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Instylla | Bedford, MA | Embolization treatment |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Karykion | , | Website outdated, doesn't seem serious |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| TTP Labtech | , | Renamed SPT Labtech |
| , | Website down Dec 2025 - Apr 2026 | |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Novotech | Taipei, Taiwan | Clinical Research |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Arzeda | Seattle, WA | Computation protein design |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| Roche | Laval, QC | Diagnostics |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
 |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Fonar | Melville, NY | Upright MRI |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| Stemetix | , | Shut down Apr 2021 |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Covalent Bioscience | , | Shut down, 2025? |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| C/M/C Biologics | , | Now CMC Biologics |
| Cue Health | , | Shut down May 2024 |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| IBA Analytics | , | Website gone Jul 2015 |
| XO1 | , | Bought by J&J, Mar 2015 |
| Alderon Biosciences | , | Presumed gone |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| FluoroPharma | , | Shell Company |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| Axplora | Shanghai, China | Purification Systems |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| American Biooptics | , | Renamed Avivo BioOptics |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Therix Medical | , | Seems gone |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Biolab | São Paulo, Brazil | Small Molecules |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| Sonus Pharma | , | Merged with Oncogenex |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| BrainXell | Madison, WI | Neuronal Research products & services |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| ImmuneXcite | , | Closed Oct 2017 |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| Recensa Therapeutics | , | Only employee gone 2018 |
| Cytovale | South SF, CA | Sepsis Detection |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| AuraSense Therapeutics | , | Renamed Exicure |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Medtronic | Memphis, TN | Medical Devices |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| Gallus | , | Bought by Patheon, Aug 2014 |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| ClinArt | , | Now ClinArt MENA |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Berg Pharma | , | Now just Berg |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Neurosave | , | Gone 2018 |
| Vascular Genesis | , | Website gone Aug 2022 |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Refeyn | Oxford , UK | Mass Photometry |
| OSI Pharmaceuticals | , | Bought by Astellas |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| Epixis | , | Acquired by VBI Vaccines |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| , | Website down Jun 2025 - Dec 2025 | |
| Gerostate Alpha | , | Shut down Dec 2024 |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| , | Liquidating Feb 2025 | |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| NeuroSearch | , | Wound down 2012 |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| SomaServe | , | Renamed ViaNautis Bio |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Apollomics | Foster City, CA | Cancer medicines |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| , | No news 2021 - Apr 2026 | |
| Celvive | , | No news from 2012-2020 |
| Aspira Labs | , | Renamed Aspira Women's Health |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| , | No website updates since 2013 as of Dec 2025 | |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| Tangent Medical Systems | , | Closed |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Tychan | , | Liquidated early 2022 |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| , | Merged with Cohance, May 2025 | |
| SiliCycle | Québec, QC | Separation Technologies |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Neuromatters | , | Shut down Dec 2019 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| Sensys Medical | , | Old company, no website, presumed defunct |
| , | Renamed PKx Bio, 2026 | |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| OraPharma | , | Owned by Valeant |
| Mitos Pharmaceuticals | , | Website Gone |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| DynoSense | , | Shut down Sep 2022 |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| Genex Pharma | Mumbai , India | Generics |
| AlloThera | , | Gone, 2018 |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| , | Website down Jun 2025 - Dec 2025 | |
| StaphOff Biotech | , | Shut down 2017 |
| DxTerity | Torrance, CA | Genomic Testing |
| Baxter | Jayuya, PR | Medication Delivery |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| , | Website down Sep 2025 - Feb 2026 | |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| CytoMol (2) | , | SF-based, Looks gone |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| Baebies | Durham, NC | Newborn Diagnostic Device |
 |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Revolution Biomanufacturing | Canton, MA | mRNA, lipid nanoparticle CDMO |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Panacos | , | Believe they are inactive |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Mitokyne | , | Renamed Mitobridge |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Peplin | , | Acquired by Leo Pharma 2009 |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| Sentien Biotechnologies | , | Shut down late 2021 |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| , | Rebranded as VivoSim, Apr 2025 | |
| DNAe | London, UK | Next-gen Sequencing |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| TandemAI | New York, NY | AI to democratize the drug development process |
| Novosis | , | Acquired by Acino, 2006 |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| PKPD International | , | Attack website |
| Frenova | Waltham, MA | Renal clinical research |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| PrognosDx Health | , | Website gone Jun 2016 |
| , | Website down Jul 2025 - Jan 2026 | |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Imcyse | , | Liquidating, Jun 2025 |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| VieVax | , | Gone Jan 2007 |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| Getinge | Vendôme, France | Medical Technology |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| , | Website down Apr 2026, seems bankrupt | |
| Synlogic | , | Shut down Sep 2024 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Pathnostics | Irvine, CA | Diagnostics |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| Acylin Therapeutics | , | Assets sold 2014 |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| Salvat | Miami, FL | Small Molecules |
| Advancells | Noida, India | Stem Cell Treatments |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| HEC | , | Website down Dec 2024 - May 2025 |
| Vante BioPharm | , | Rebranded at Sebra |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| Retroject | , | Seems gone |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Symbollon | , | Gone |
| , | Website down Dec 2025 - Jun 2026 | |
| , | No news 2021 - Jan 2026 | |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| Guardion Health Sciences | , | Shut down |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| , | Shut down Oct 2023 | |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Accellacare | Downers Grove, IL | Clinical Research |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Apalexo Biotechnologie | , | No info, probably gone |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| Pharming Group | Leiden, Netherlands | Biologics |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| CellCarta | Montréal, QC | Clinical Research |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| Cymbiotics | , | Gone 2019-2020 |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| AblaCor | , | Shut down May 2019 |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| , | Website down Oct 2025 - Feb 2026 | |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Microbia-pe | , | Renamed Microbia |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Genuine Biosystem | Chennai, India | IVD Products |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Onyvax | , | Assets Apparently Acquired |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| Inference | Pune, India | Clinical Trial Services |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| Elite Research Institute | , | Gone, May 2018 |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Bio-Processing Alliance | , | Website now for a training company |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| , | Assets acquired by Alexion, Feb 2011 | |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| Entelos | , | Bankrupt |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| Nano Oncology | , | Gone |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Lexogen | Vienna, Austria | RNA kits |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| 3D Biomatrix | , | Closed down |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Helus Pharma | Toronto, ON | Psychedelics |
| Clario | Philadelphia, PA | Clinical Services |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| , | No news 2015 - Jan 2026 | |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Vaxart | South SF, CA | Oral Vaccines |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Tryton Medical | , | Shut down Jan 2021 |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| ChemRegen | , | Seems gone Jan 2022 |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Medtronic | Minneapolis, MN | Medical Devices |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| , | Acquired by Certara, Oct 2024 | |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| AFID Therapeutics | , | Gone 2012 |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| , | Website down Aug 2025 - Jan 2026 | |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| preclinics | Potsdam, Germany | Contract Research |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| , | Acquired by EPI, Mar 2022 | |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| , | Renamed Hubot, May 2026 | |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Syndexa Pharm | , | Closed Jul 2013 |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| CO.DON | Teltow, Germany | Cell Therapies |
| , | Liquidating, Mar 2025 | |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| OFD Biopharma | Albany, OR | Lyophilization |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| IMMY | Norman, OK | Fungal Diagnostics |
| Roche | Mannheim, Germany | Diagnostics |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Zephyr AI | McLean, VA | AI Data Analysis |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| , | Website down Nov 2025 - Mar 2026 | |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| Niramai | London, UK | AI-breast cancer detection device |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| DecImmune Therapeutics | , | Gone 2017 |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| Tempered Biosciences | , | Absurd website has to be gone |
| , | Renamed LeonaBio, Jan 2026 | |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| , | Part of Evogene | |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| Piramal | Pithampur, India | CDMO |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| LENSAR | Orlando, FL | Cataract Laser |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| MacuClear | , | Website gone Jan 2019 |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| Quentis Therapeutics | , | Shut down late 2020 |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| Seraph Biosciences | Detroit, MI | POC Pathogen Detection |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Cytiva | Freiburg, Germany | Medical Devices |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| ViroPharma | , | Bought by Shire Jan 2014 |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| , | Main person has four other jobs, Dec 2025 | |
| Quantamerix | , | No info since 2012, never registered in MA |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| BioRelix | , | Restructured. Unknown Status. |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Axium Pharmaceuticals | , | Dissolved |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Advanced Vision Science | , | |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Concordia Healthcare | , | Now Concordia International |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Bakhu Pharma | , | Bankrupt, location sold |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| , | Shut down Nov 2025, Tempus acquired assets | |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| AlphaVax | , | No employees on LI. Not sure active |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Correlogic | , | Assets bought by Vermillion 2011 |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Allergenics Inc | , | Closed Mar 2007 |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| Celerion | Belfast, UK | Clinical Research |
| Curevo Vaccine | Bothell, WA | Vaccines |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Martek Biosciences | , | Bought by DSM |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| Enci Therapeutics | , | No website, business suspended by NC |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| Biomatters | , | Renamed Geneious |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Doer Biologics | Hangzhou, China | Biologics |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Azad Pharma | Montreal, QC | APIs, generics |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| Mindflow Design | , | Now part of MPE |
| McGee Pharma | , | Merged with Pharmalex |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Minntech | , | Now Medivators |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| FIT Biotech | , | Bankrupt Feb 2019 |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| Zyagen | San Diego, CA | Life Science Reagents |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| InsightRX | San Francisco, CA | Dosing Model |
| , | Website down Oct 2025 - Feb 2026 | |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Recipharm | Strangnas, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| NeuroFx | , | Renamed Theratome Bio |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| Nephrion | , | Closed 2006? |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Centocor | , | Renamed Janssen Biotech |
| , | Website down Jan 2026 - May 2026 | |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Micrologix Biotech | , | Renamed Migenix |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| GeneTrol | , | Merged with CytoPharm |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Alcon | Houston, TX | Eye-Care Products |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| EmpowerPharm | , | Shut down |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| AllerMAbs | , | Website gone Oct 2022 |
| Allogene Therapeutics | South SF, CA | CAR-T |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| HistoIndex | Hangzhou, China | Digital Pathology |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| , | Acquired by Inizio, Dec 2025 | |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| Mankind Pharma | New Delhi, India | OTC? |
| Brightflow Medical | Paris, France | Heart Failure Device |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Roche | Basel, Switzerland | Small Molecules |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Gene Sciences | , | Shut Down Jul 2019 |
| Nasseo | , | Gone |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| MyoSyntax | , | Gone 2021 |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| TruGenomix | , | Renamed Polaris Genomics |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Apollomics | Xiaoshan, China | Cancer medicines |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| , | Merged with DefiniGEN to become pixl.bio | |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Velomedix | , | Shut down 2014 |
| NextImmune | , | Renamed NXI Therapeutics |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| Genomica | , | Shut down Sep 2022 |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| , | Liquidated 2024 | |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| , | Renamed Carvolix, Feb 2026 | |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Catalyz | , | Gone |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Xylo | Boulder, CO | Psychedelics |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| Fornax Biotech | , | Dissolved Jun 2021 |
| LunaDNA | , | Shutting down Jan 2024 |
| SVBio | , | Changed name to Lifecode |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Biocious Life Sciences | , | Now Agilent |
| BionX Medical | , | Acquired by Ottobock |
| VaxInnate | , | Dissolved Feb 2017 |
| Appia Bio | , | Shut down Aug 2025 |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| , | Website down May 2025 - Nov 2025 | |
| PhotoSonix Medical | , | Now a licensing outift |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| ApoVax | , | Shut down Jul 2014 |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| , | Website down Oct 2025 - Feb 2026 | |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| Theracos | , | Renamed TheracosBio |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Scientific Industries | Bohemia, NY | Lab equipment |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
 |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Stryker | San Jose, CA | Medical Devices |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| BRAND | Wertheim, Germany | Liquid Handling |
| , | Website taken over, Nov 2025 | |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| GSK | Hamilton, MT | Vaccine additive |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| 76Bio | , | Shut down Jan 2025 |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| Avaxia Biologics | , | IP acquired by Circle33 |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Boca Pharmacal | , | Bought by Qualitest |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Syneos Health | Morrisville, NC | Clinical Development |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| CLCbio | , | Acquired by Qiagen, 2013 |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| , | Website down Sep 2025 - Feb 2026 | |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| LumaBridge | San Antonio, TX | Clinical Research |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| QuantRx Biomedical | , | Shell company |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Inflammix | , | Renamed AnchorBio Solutions |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Hemanext | Lexington, MA | Transfusion Technologies |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| RadioRx | , | Now EpicentRx |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| Apolife | , | Renamed Biosavita |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| Pharmanovia | London, UK | Acquisition of Drugs |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Chrysalis | Burlington, MA | GMP Space |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Resilience | East Norriton, PA | Biomanufacturing |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| Avax Technologies | , | Gone |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| BioPhyZica | , | Gone 2016 |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Zenosense | , | No website, shell company Nov 2020 |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| , | Part of Greenpharma | |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| MSD | Leopardstown, Ireland | Small Molecules |
| , | Renamed Motive Health, Jul 2023 | |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Molecular Loop | Woburn, MA | NGS Technology |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| , | Acquired by IMA Group, Oct 2025 | |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| GEROPHARM | Moscow , Russia | Large drug maker |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| ModeX Therapeutics | Weston, MA | Biologics |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| SenzaGen | Lund, Sweden | Genomic Assays |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Sharp | Bethlehem, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Protypia | , | |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| CombImmune | , | Website Gone Jul 2015 |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| Conformis | , | |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Orthofix International | Lewisville, TX | Medical Devices |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| Macrocure | , | Merged into Leap Therapeutics |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| CoaguSense | Fremont, CA | Coagulation monitor |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Groton Biosystems | , | Gone before Jun 2015 |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| Vista.ai | Palo Alto, CA | MRI Software |
| ProPharma Group | Washington, DC | Consulting |
| Pharmaron | Coventry, RI | API Manufacturing |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Thermo Fisher | Bend, OR | CDMO |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Abiologics | Cambridge, MA | Synteins |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| ArunA Biomedical | , | |
| Stemnovate | Cambridge, UK | Research Cells |
| Amphora Medical | , | Shut down May 2019 |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| AbRegen | , | Website gone, Mar 2019 |
| ACROBiosystems | Basel, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Novacta | , | Website Gone, no info |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| Silktap | , | Liquid silk. Site gone |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| Tanai Therapeutics | , | Obesity Treatment |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Solventum | St. Paul, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Psomagen | Rockville, MD | Genetic Sequencing |
| , | Website down Jul 2025 - Jan 2026 | |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| E3X Bio | , | Shut Down Mar 2019 |
| AM2PAT | , | Trouble with contaminated products, gone |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| Hydra Biosciences | , | Website gone Mar 2019 |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| Inductive Bio | Virtual, US | Compound Optimization |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| SEQENS | Ecully, France | APIs, Ingredients |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| NuVascular Technologies | , | Shut down Nov 2021 |
| MicroPort | Saluggia, Italy | Medical Devices |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| Gentian USA | Moss, Norway | IVD Products |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Remedium Bio | Needham, MA | Gene Therapy |
| Cancer Insight | , | Renamed LumaBridge |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| , | Shut down late 2025 | |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| icometrix | Boston, MA | Imaging AI |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| , | Renamed BreezeBio, Feb 2026 | |
| Cherry Biotech | Paris, France | Organoid Culture |
| Coferon | , | Renamed BlinkBio |
| Meissner | Camarillo, CA | Lab Systems |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| Abbott | Mississauga, ON | Diagnostics |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| OBI Pharma | Taipei, Taiwan | Biologics |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| Squarex | , | Gone as of Oct 2021 |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| Mojave Therapeutics | , | Gone |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Synedgen | Claremont, CA | Biofilm Control |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| TumorGen | San Diego, CA | Cancer Treatments |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| , | Website down Sep 2025 - Jan 2026 | |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Predicine | Hayward, CA | Liquid Biopsy |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| Gilead | Edmonton, AB | Small Molecules |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Eden Biodesign | , | Bought by Watson |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| PluroGen Therapeutics | , | Gone 2013 |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| Scion Medical Technologies | , | Gone 2016 |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Humanyx | , | No website, Seems gone |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Clarapath | Hawthorne, NY | Pathology Device |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| InterX | , | Acquired by NeoTX, May 2022 |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Alfama | , | Merged into Proterris, May 2017 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| CompleGen | , | Shut down Aug 2021 |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Vectura | , | |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| HCW Biologics | Miramar, FL | Immunotherapy |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Orphan Therapeutics | , | Gone Mar 2010 |
| XaTek | , | No news 2021 - Feb 2025 |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| DFE Pharma | Goch, Germany | Excipients |
| Spear Bio | Woburn, MA | Immunoassays |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| nference | Cambridge, MA | Clinical AI |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| CardioCreate | , | Shut Down Jun 2020 |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| VedaLab | Cerisé, France | IVD rapid tests |
| Xegen | Gemenos, France | NGS Data Analysis |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| DDi | Princeton, NJ | Clinical Software |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| CTK Biotech | Poway, CA | Diagnostics |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| Pharmatrope | , | Absurd website 2020-2023 |
| Eternans | , | Shut down Jul 2022 |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Moon Surgical | Paris, France | Robotic Surgery System |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| Opsonix | , | Shut down May 2018 |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Protein Metrics | Boston, MA | Protein characterization software |
| PharmaVigilant | , | Gone 2014 |
| VLST Corp | , | Wound Down, Jun 2013 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| , | Part of Normec | |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| Beacle | , | Founder gone, no info |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| RS Medical | Vancouver, WA | Medical Devices |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| , | Website down Aug 2025 - Jan 2026 | |
| Greenstone Biosciences | Palo Alto, CA | |
| Novo Nordisk | Beijing, China | Inflammation Research |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| , | Shut down 2024 | |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| Innomab | , | Gone 2017 |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Stada | Belgrade, Serbia | Generics |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| Baxter | Marion, NC | Medication Delivery |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Gen Plus | Munich, Germany | Formulation |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| BioSpherex | , | Renamed Metabiomics |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Restek | Bellefonte, PA | LCGC Equipment |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Pfizer | McPherson, KS | Sterile Injectables |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| BioDot | Irvine, CA | Equipment |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| ProSci | Poway, CA | Antibodies, etc. |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Triage Wireless | , | Now named Sotera Wireless |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| Repco Development Technologies | , | Renamed 3Dispense |
| Baccuico | , | Renamed Bactobio |
| BinaryBio | , | Out of business Jul 2015 |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Talee Bio | , | Renamed Spirovant Sciences |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| SphynKx Therapeutics | , | Gone |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Stada | Vršac, Serbia | Generics |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| Accellacare | Bristol, TN | Clinical Research |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| VasoNova | , | Acquired by Teleflex Medical |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Zuma Biosciences | , | Company Gone |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Olon USA | Concord, OH | Contract Research |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Chrysalis | Waltham, MA | GMP Space |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| , | Shut down Feb 2026 | |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Jenken Biosciences | , | Shut down by 2014 |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Proscia | , | |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Celixir | , | Shell acquired Dec 2023 |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| BioDatomics | , | Website gone Jan 2019 |
| Celregen | Hangzhou, China | iPSC |
| , | Website down Jan 2026 - May 2026 | |
| mibe Arzneimittel | Brehna, Germany | Generics |
| ObvioHealth | New York, NY | Clinical Study Software |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| MiNA Therapeutics | London, UK | Small activating RNA |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| AVEO Oncology | Boston, MA | Small Molecules |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Metrics Inc | , | Renamed Metrics Contract Services |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| MyOme | Palo Alto, CA | Genomic Analysis |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Jet Life Sciences | Hyderabad, India | APIs |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| Proxygen | Vienna, Austria | Cancer Therapies |
| Zai Lab | Shanghai, China | Small Molecules |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| , | Website down Jul 2025 - Jan 2026 | |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| BioLegacy Research | San Diego, CA | Contract Research |
| Rx3 | , | Now Trius Therapeutics |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| Therics | , | Acquired by Integra |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| Plexanome | , | Gone 2018 |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Delpor | Brisbane, CA | Drug Delivery System |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Trillium Diagnostics | , | Closed Jul 2016 |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| Piramal | Mumbai, India | CDMO |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Alacrity Biosciences | , | Gone post-2011 |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| CEL-SCI | Vienna, VA | Biologics |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Avail Medsystems | , | Tech sold Mar 2024 |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Molecular Logix | , | Gone, Dec 2018 |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Sanovel | Silivri, Turkey | Generics |
| Clinical Microbiomics | , | Merged into cmbio |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| StemCell2MAX | , | Website gone Apr 2019 |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| Vyriad | Rochester, MN | Immunovirotherapy |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| MicroPort | Shanghai, China | Medical Devices |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| Innerpulse | , | Gone maybe 2013 |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Apobiologix | Toronto, ON | Biosimilars |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Eos Biotechnology | , | Gone 2005 |
| Endotis Pharma | , | Founded in 2003. No info |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Enesi Pharma | , | Renamed aVaxziPen |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Analiza | Cleveland, OH | Physicochemical Services |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| Simpirica Spine | , | Became Empirical Spine |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Cognosetta | , | Gone 2021 |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Slainte Bioceuticals | , | Gone |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Rosedale Medical | , | Now Intuity Medical |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| ReSync Bio | , | Acquired by Benchling 2025 |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Bracco | Monroe Township, NJ | Imaging |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Viva Biotech | Jiaxing , China | Contract Research |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| Medallion Therapeutics | , | Shut down 2018 |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| PluriSelect | El Cajon, CA | Cell Separation |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| Apath | , | No website update since 2014, Feb 2023 |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Metrochem | Hyderabad , India | APIs |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| icometrix | Leuven, Belgium | Imaging AI |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| XtalPi | Shenzhen, China | AI Drug Design |
| , | Renamed AtaiBeckley | |
| Palmaz Scientific | , | Bankrupt, 2016 |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| Revvity | Waltham, MA | Diagnostics, Services |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| South Coast Clinical Trials | , | |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| , | part of ElevateBio; fka LifeEDIT | |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| Santen | Emeryville, CA | Ophthalmics |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| NS Pharma | Paramus, NJ | Small Molecule |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Rafagen | , | Website redirecting to Rophibio |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Bio-ops | , | Now SVA |
| Quanta Biosciences | , | Renamed QuantaBio |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| NemaPharm | , | Defunct? |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| Axplora | Pompey, France | CDMO Services |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| , | No news 2018 - May 2026 | |
| myoscience | , | Renamed iovera |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| Akermin | , | Closed |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| CeNeRx | , | Shut Down, 2013 |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| , | Website down Aug 2025 - Jan 2026 | |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| CORONIS | Athens, Greece | Clinical Studies |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
 |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| TissueNetix | , | Gone Feb 2018 |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| Sophiris Bio | , | Shut down May 2020 |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| Cibiem | , | Shut down May 2021 |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| , | Shut down Apr 2026 | |
| Apollo Spine | , | Renamed G6 Spine |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| ReproSource | Marlborough, MA | Fertility Testing |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Echo | San Diego, CA | Microscopy |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| NantHealth | El Segundo, CA | Diagnostics |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| CyteGen | , | 2015 founded, website never active |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| , | Website down, COO gone Oct 2025 | |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| Cryoniss | Deeside, UK | Bio Banking |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Verasonics | Kirkland, WA | Research Ultrasound |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Elucid | Boston, MA | Arterial Analysis Software |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| RegenoCELL Therapeutics | , | Presumed gone |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Genomadix | Kanata, ON | Portable PCR |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Universal Precision Instruments, Inc. | , | |
| Bausch Health | Laval, QC | Small Molecules |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| Convalife Pharmaceuticals | Shanghai, China | Oncology, viruses and aging treatments; bispecific antibodies, small molecules |
| US Labs | , | Bought by Labcorp |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| Formation Bio | New York, NY | AI Drug Discovery |
| , | Website down Jul 2025 - Dec 2025 | |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Genexa | , | Shut down before Nov 2023 |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Alera Labs | Durham, NC | Contract Research & Services |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Validation Associates | Herndon, VA | Validation Consulting |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Agrisera | Vännäs, Sweden | Antibodies |
| VAXX | , | Not sure what happened to them |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| Protein Forest | , | Bought by Cell Biosciences |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Delpharm | Evreux, France | Contract Manufacturing |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| , | ||
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Suir Pharma | , | Bankrupt, May 2016 |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| Pierce | , | Part of Thermo Fisher |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Sunho Biologics | Nanjing, China | Biologics |
| Aureon Biosciences | , | Insolvency Proceedings |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Accium BioSciences | , | Shut down Oct 2024 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Theranos | , | Dissolving, Sep 2018 |
| QuA Vodis | , | Gone |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Mendelian | London, UK | Rare Disease Diagnosis |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Perlara PBC | , | Shut down Feb 2019 |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Medochemie | Limassol, Cyprus | Generics |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| GliaMed | , | Website copyright 2009, seems defunct |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| Elixir Pharmaceuticals | , | Gone |
| , | Now PamDx, May 2026 | |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| , | Acquired by Bruker, Sep 2020 | |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| NanoSort | , | Renamed NanoCellect |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Indocruit | , | Gone |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Imeka | Sherbrooke, QC | Neuroimaging |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| DDL | Edison, NJ | Device Testing |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| NeuroTherapeutics | , | Gone |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Chrysalis | Morrisville, NC | GMP Space |
| Roche | Tucson, AZ | Diagnostics |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| IQVIA | San Diego, CA | Clinical Research |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| , | Website down Dec 2025 - Jun 2026 | |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| BioGaia | Stockholm, Sweden | Probiotics |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Salus Bioscience | , | Forfeited in CA |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| Chiromics | , | Website now a penny stock shill |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| OP2 Drugs | , | Website gone Jan 2020 |
| Kumuda | , | Website gone Mar 2023 |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| QInstruments | Jena, Germany | Lab Instruments |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Autotelic | , | Gone 2022 |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| Keenova | Malvern, PA | Small Molecules |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| MedinCell | Jacou, France | API Delivery Gel |
| CoAxia | , | Closed down Spring 2013 |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Mitokine Bioscience | , | Seems to be a research library now |
| , | Website down Jun 2025 - Dec 2025 | |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| DMD Therapeutics | , | Gone Nov 2018 |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| VitaCyte | Indianapolis, IN | Collagenase |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Anumana | Cambridge, MA | AI ECG reading |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Dorphan | , | Shut down so owner could spend more time skiing |
| , | Inactive May 2025 | |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Assurance Scientific Laboratories | Austin, TX | Molecular Technologies |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| OncoQr | , | No news 2017 - Oct 2024 |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Telis Bioscience | , | Renamed Alvea |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Basecamp Research | London, UK | AI-Biology Data |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Oticon | Somerset, NJ | Hearing Aids |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| CanBas | Shizuoka, Japan | Small Molecules |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| METiS Technologies | , | |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Advarra | Columbia, MD | Regulatory Consulting |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Novometrics | , | Dissolved Dec 2019 |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Abnovel | , | Gone Jul 2010 |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Website down Oct 2025 - Feb 2026 | |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| , | Renamed Ensera, Oct 2025 | |
| Holloway America | Springfield, MO | Vessels, Tanks |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| CoRegen | Aspen, CO | Genetically Engineered T Reg Cells |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| Piramal | Ennore, India | CDMO |
| Ativa Medical | , | Renamed Immune IQ? |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Solano Pharmaceuticals | , | Website gone |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| ProteinLinks | , | Seem gone |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| AmProtein | , | Presumed Gone |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| , | Website down Sep 2025 - Feb 2026 | |
| Exodon | , | Website taken over, Jul 2014 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| Nuventra Pharma Sciences | , | Now Allucent |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Gene Techno Science | , | Renamed Kidswell Bio |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Ergomed | Kiev, Ukraine | Clinical Research |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| EnquBio | San Diego, CA | Contract Research & Services |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Enterin | , | Website taken over Feb 2025 |
| Life Couriers | Munich, Germany | Diagnostics |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| Hovione | Macau, China | Contract Manufacturing |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| Amrita Therapeutics | , | Seems gone |
| Photonion | Schwerin, Germany | Analytical Equipment |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Tequesta BioScience | , | Defunct |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| Stada | Bad Vilbel, Germany | Generics |
| AliveDx | Eysins, Switzerland | Diagnostics |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| Redpoint Research | , | Gone 2019 |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Getinge | Wayne, NJ | Medical Technology |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| , | Website down Nov 2025 - Apr 2026 | |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| , | Website down Jul 2025 - Dec 2025 | |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| Santen | Nara, Japan | Ophthalmics |
| Aracea Therapeutics | , | No website Aug 2022 |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| , | Acquired by hVIVO, Dec 2019 | |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Advantagene | , | Renamed Candel Therapeutics |
| Parexel | Sheffield, UK | Clinical Research |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Ipsen | Sumter, SC | Biologics |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| Afferon | , | Gone, no info |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| , | Shut down 2025 | |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Flux Biosciences | , | Shut down, ~2022 |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Cytoskeleton | Denver, CO | Research Products |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| ImmunoBiochem | , | No news 2018 -2023 |
| , | No news 2020 - Apr 2026 | |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| , | Website down Dec 2025 - Feb 2026 | |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Saghmos Therapeutics | , | |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Doctor Pack | Bangalore, India | Packaging |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Platelet BioGenesis | , | renamed PlateletBio |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Owkin | New York, NY | AI for Medical Research |
| SK Biotek | , | part of SK pharmteco |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| STC Biologics | Newton, MA | Services |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| COOL-BIO | , | Gone |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Celerion | Zurich, Switzerland | Clinical Research |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| RxGen | , | Renamed Virscio, Jan 2020 |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Compucyte | , | Sold Assets to Thor Labs |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Abnovo | , | Gone |
| Asuragen | Austin, TX | Diagnostics |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| PredxBio | Pittsburgh, PA | Image Analysis |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Altasciences | Overland Park, KS | Contract Research |
| Taligen Therapeutics | , | Acquired by Alexion |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
 |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| SR Pharma | , | Now Silence Therapeutics |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Tecomet | Kenosha, WI | Implant Components |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| Core Dynamics | , | Gone |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Sorbent Therapeutics | , | Gone post 2014 |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Curis | Lexington, MA | Small Molecules |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| Alchemgen | , | Gone |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| , | Website down Jan 2026 - May 2026 | |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Divergence | , | Bought by Monsanto |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| Angex Pharmaceuticals | , | Gone 2018 |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Sepiatec | Berlin, Germany | Separation Systems |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| BG medicine | , | Gone 2019 |
| Stimwave | , | Bankrupt, Oct 2022 |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Profluent | Emeryville, CA | AI Protein Creation |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| Abpro | Burlington, MA | Antibodies |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| Vyteris | , | Bankrupt 2012 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Raytone Bio | , | |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Simbex | Lebanon, NH | Biomechanical devices |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| Imstem Biotechnology | , | Website gone May 2021 |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Vericel | Cambridge, MA | Cellular Therapy |
| Quellthera | , | Subsumed into Liveleaf |
| SuperX | , | Gone |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Invectys | Paris, France | DNA Vaccine |
| EMS | Hortolândia, Brazil | Small Molecules |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Warnex | , | Merged into DIAGNOS Inc |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| Procertus | , | Website Gone, Apr 2016 |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| Hana Biosciences | , | Now Talon Therapeutics |
| Norac Pharma | Azusa, CA | API Manufacturing |
| Nanoferix | , | Renamed Pendant Biosciences |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Targeson | , | Website gone, Mar 2017 |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Neural Analytics | , | Renamed NovaSignal |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Glen Research | Sterling, VA | Oligos |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Baxter | Grosotto, Italy | Medication Delivery |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| Generex Biotechnology | , | Website gone Feb 2024 |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| , | Acquired by Sensei Biotherapeutics, Feb 2026 | |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| , | Website down Jul 2025 - Jan 2026 | |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| , | Website down Aug 2025 - Jan 2026 | |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| MiniMed | Northridge, CA | Diabetes Management |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| White Biotech Solutions | , | Shut Down 2019 |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Medtronic | Danvers, MA | Medical Devices |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| SilaGene | , | Gone |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| , | Dissolved, Apr 2024 | |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Lung Bioengineering | , | Part of United Therapeutics |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| , | Website down Oct 2025 - Jan 2026 | |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Gensia Sicor | , | Renamed Sicor |
| Chiron | , | Bought by Novartis |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Sirius Genomics | , | Gone |
| Acuvax | , | Pivoted to investments, 2014 |
| Boragen | , | Renamed Reactive Biosciences |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Hasten Pharma | Hefei, China | Small Molecules |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Veryan Medical | Horsham, UK | Helical Stent |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| Bioclinica | , | Merged with ERT, 2021 |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| Valsphere | , | Website gone Nov 2019 |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Senetek | , | Not sure what happened, no site, seem gone |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Ergomed | Frankfurt, Germany | Clinical Research |
| SCOLR Pharma | , | Closed Mar 2013 |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Anazen Diagnostics | , | Part of Cardiox |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Thyritope Biosciences | , | Closed Oct 2016 |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| , | Website down Nov 2025 - Mar 2026 | |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Delpharm | Huningue, France | Contract Manufacturing |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Karius | Redwood City, CA | Diagnostics |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| Provasculon | , | Website Gone, Apr 2014 |
| Amaranth Medical | , | Website gone, Apr 2019 |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| hC Bioscience | , | Shut down Mar 2025 |
| Celerion | Montreal, QC | Clinical Research |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| TocopheRx | , | Gone before 2019 |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| EyeCyte | , | Gone 2014 |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Tarsa Therapeutics | , | Product rights acquired |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| , | Website down Dec 2025 - Jun 2026 | |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Molecular Sensing | , | Business revoked Aug 2019 |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Genlantis | , | Acquired by AMSBIO |
| Splice Histology | Worcester, MA | Histopathology Services |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Precision Research Institute | , | Shut down Apr 2024 |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| Prognosys Bioscience | , | 10 years in stealth mode |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| CNS Research | , | Seem gone, 2020 |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| , | No news 2017 - Apr 2026 | |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Vernacare | Newtown, UK | Surgical Devices |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| , | Website down Sep 2025 - Feb 2026 | |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Ansata Therapeutics | , | Out of business 2007 |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| Molecular Detection Inc | , | Gone 2016 |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| Cyto360 | , | Website gone Aug 2018 |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Kona Medical | , | Closed, Dec 2016 |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| ProPharma Group | San Diego, CA | Consulting |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| Accellacare | Cary, NC | Clinical Research |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| Cdymax | Bangalore, India | APIs |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| PNP Therapeutics | Birmingham, AL | Outlicensed sole product Sep 2021 |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Almac | Durham, NC | Pharmaceutical Services |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| GT Biologics | , | Renamed 4D Pharma Research |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| CMP Pharma | Farmville, NC | Small Molecules |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Vadovations | , | No info. 2012 SBIR grant |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Chesapeake Biological Labs | , | Now known as Cangene |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| Cytokinetics | South SF, CA | Small Molecules |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| ICU Medical | San Clemente, CA | Disposable medical products |
| PhytoMedical | , | Apparently Gone |
| , | Acquired by Boston Scientific, Jan 2025 | |
| , | Website down Sep 2025 - Dec 2025 | |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Centricity Research | Toronto, ON | Clinical Research |
| , | business filings late Oct 2023 - Oct 2025 | |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| Oncodesign Services | Dijon, France | Preclinical services |
| Nensius Research | , | Website Gone |
| SIRGA Advanced Biopharma | , | Appears defunct |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| Medicure | Winnipeg, MB | Small Molecule |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| BioSyntech | , | Bought by Piramal |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Berlex | , | Now Bayer |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| AGILeBiotics | , | Shut down 2024? |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| Develco Pharma | Schopfheim, Germany | Generics |
| Aitia | Cambridge, MA | Analytics |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| CanCure | , | No news 2017 - 2024 |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| Boston Scientific | Cork, Ireland | Medical Devices |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| , | ||
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| PharmaDerm | , | Part of Sandoz |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Envision Genomics | , | Website gone Nov 2019 |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Accellacare | Knoxville, TN | Clinical Research |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| Zai Lab | Hong Kong, China | Small Molecules |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Octapharma | Vienna, Austria | Plasma Products |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Avivo BioOptics | , | Website down Dec 2022 |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Zensun | , | Website gone Jan 2019, Chinese company |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| , | Website down Dec 2025 - Apr 2026 | |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| , | Winding down Jan 2026 | |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Esculon | , | Seems defunct, employees gone |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| RhinoCyte | , | Website moved to a marketing agency domain |
| RelonChem | Cheshire, UK | Generics |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| , | ||
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| Roche | Pleasanton, CA | Diagnostics |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| Mabqi | Grabels, France | Antibody Discovery |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Orochem | Naperville, IL | Reagents, Automation |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| Grifols | Durham, NC | Biologics |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| Inno Biologics | , | Website gone Jun 2020 |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Amniox Medical | , | Folded into BioTissue |
| SynapDx | , | Shut down, Mar 2017 |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| , | Renamed Torpedo Therapeutics | |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| NEXGEL | Langhorne, PA | Hydrogels |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| SmartCells | , | Bought by Merck Dec 2010 |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Molecular Partners | Zurich, Switzerland | Biologics |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| ZyGEM | , | Renamed MicroGEM |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| Zila | , | Bought by Tolmar, Jul 2009 |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| TME Pharma | Berlin, Germany | L-aptamers |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Actavalon | , | Shut down Dec 2020 |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Ansaris | , | Gone |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Axcella Health | , | Renamed Axcella Therapeutics |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| EVA Pharma | Giza, Egypt | Branded Generics |
| Infectex | , | Website taken over May 2020 |
| Securecell | Urdorf, Switzerland | Lab automation |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| , | Website down Jun 2025 - Dec 2025 | |
| Genopis | , | Acquired by Wacker Feb 2021 |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Emergo by UL | Austin, TX | Medical device consulting |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| Unigene Laboratories | , | Closed 2013 |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| IncellDx | , | Renamed HealthBio AI |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| NovoLipid | , | Website Gone |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Regenicin | , | Residential address, three employees, no money |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| , | Website down Jan 2026 - May 2026 | |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| iWel | Exton, PA | Glucose Meters |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Alliqua | Langhorne, PA | Hydrogels |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Entropia Biosciences | , | Shut Down June 2019 |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Plaxgen | , | Shut Down 2019 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| , | Acquired by Medicover, Apr 2026 | |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Sequel Pharmaceuticals | , | Gone |
| NascaCell | , | German Aptamer company, not sure of fate |
| Predictive Biosciences | , | Closed 2013 |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| CYTOO Cell Architects | , | |
| Nexus Spine | Draper, UT | Spinal Implants |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Accera | , | Renamed Cerecin, Oct 2018 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Pace | San German, PR | Analytical Testing, CDMO |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| BalinBac Therapeutics | , | Gone 2018 |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Kailo Pharma | , | |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| Hemay Pharmaceutical | Tianjin, China | |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| BBB Therapeutics | , | Bankrupt 2015 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| 1CellBio | , | Gone Jun 2019 |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Jerini | , | Acquired by Shire, 2008 |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| AbGenomics | , | Renamed Altrubio |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Alxerion Biotech | , | Gone May 2021 |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| CoMind | London, UK | Non-invasive brain monitoring system |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| EQL Pharma | Lund, Sweden | Generics |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Chroma Medicine | , | |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| , | No news 2018 - Sep 2025 | |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| SanBio BV | Uden, Netherlands | Antibodies |
| SineuGene | Beijing, China | Gene Therapy |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| Spyryx Biosciences | , | Shut down 2019 |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| NKMax America | , | Renamed NKGEN Biotech |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| bioMerieux | Cambridge, MA | Diagnostics |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Alnis BioSciences | , | No info |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Kiecana Clinical Research | , | Now KCR |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Atherotech | , | Shut down Feb 2016 |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Accellacare | Winston-Salem, NC | Clinical Research |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| SuraMedical | , | Most employees left, not registered in MN |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| Antibiotice | Iasi, Romania | Generics |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| PulmoGeniX | , | No business filings 2016-2020 |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| R2M Pharma | South SF, CA | Drug Development Services |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Olymvax | Chengdu, China | Vaccines |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Parsolex | , | |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Innovagen | Lund, Sweden | Custom antibody development |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| Halloran Consulting Group | Boston, MA | Consulting |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| , | Website down Aug 2025 - Jan 2026 | |
| PeriCor Therapeutics | , | Website Gone |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Ascenta Therapeutics | , | Gone |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Cytoplex Biosciences | , | Gone |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Kulira Technologies | , | Website Gone Oct 2016 |
| GeneDx | Gaithersburg, MD | Genetic Data |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation psuedo-subsidiary | |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Ascend Genomics | , | Shut down |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Oncology Clinical Research | , | Gone |
| , | Part of SBO Hearing, Feb 2026 | |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Cytiva | Tokyo, Japan | Medical Devices |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Terpenoid Therapeutics | , | Gone |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Heart Tronics | , | Effectively defunct after scandal |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| C3 Jian | , | Now C3J Therapeutics |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Sundia | , | Part of BioDuro |
| , | Acquired by Sebia, Sep 2024 | |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Genova Clinical Research | , | Gone, 2014 |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| , | Subsumed into Synoptics | |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| BioFluentLabs | , | Shut down July 2012 |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Pathfinder Cell Therapy | , | Gone 2016 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Ascelegen | , | Closed |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| , | Acquired by Instem, Jul 2025 | |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| OperaCRO | , | Now part of Tigermed |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Celavie Biosciences | , | Shut down Mar 2024 |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Ribon Therapeutics | , | Shut down May 2024 |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| BGI | Hong Kong, China | Genetic Testing |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Avenir Pharma | , | No longer active |
| CSSi | , | |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| Biodel | , | Merged with Albireo, Oct 2016 |
| LinKinVax | , | Rebranded as EnnoDC |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Avatar Medical | Paris, France | Surgical Visualization |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| AxoGlia Therapeutics | , | Ran out of money |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| Neose | , | Gone |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| BZL Biologics | , | Gone 2003 |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Healx | Cambridge, UK | AI Drug Discovery |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| XellSmart | Suzhou, China | Cell Therapy |
| Grifols | Clayton, NC | Biologics |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Obenomics | , | No website Apr 2014 |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Oncofactor | , | Gone 2016 |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Acquired by Ligthouse Lab Services | |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| , | Website down Feb 2025 - Dec 2025 | |
| Covaris | Woburn, MA | DNA Sample Prep |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| Progenika | , | Bought by Grifols |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Intercytex | , | Liquidated |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| Cadex Genomics | , | Shut down Jul 2024 |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Bayer | Mexico City, Mexico | Small Molecules |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| Gentell | Yardley, PA | Wound Care |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Expression Patholgy | , | Now OncoPlexDx |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| , | Website down May 2025 - Dec 2025 | |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| , | No news 2017 - Apr 2026 | |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Trimeris | , | Merged with Synageva |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Biocoat | Horsham, PA | Medical Device Coatings |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Excelya | Boulogne, France | Clinical Research |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| DDL | Irvine, CA | Device Testing |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| Soletics | , | Website gone Jun 2021 |
| Terapio | , | Website Gone, Sep 2020 |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| MetaStat | , | Website gone May 2019; Shell Company |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| , | Website down Oct 2025 - Feb 2026 | |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Scholar Rock | Cambridge, MA | Biologics |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Bayer | Barcelona, Spain | Small Molecules |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| Texcell | Evry, France | Contract Research |
| TAI Diagnostics | , | Gone |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| Neuronax | , | Renamed Axoltis Pharma |
 |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Embecta | Parsippany, NJ | Diabetes Care |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Medistem | , | Bought by Intrexon Dec 2013 |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Boston Scientific | Galway, Ireland | Medical Devices |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| XtalPi | Cambridge, MA | AI Drug Design |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| TriVirix | , | Now Nortech Life Sciences |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| NK CellTech | Shanghai, China | Cell Therapies |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| Sequella | , | Ancient website ©2017, last news 2017 |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| DiObex | , | Shut Down 2009 |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| , | Website down Oct 2025 - Feb 2026 | |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| Artificial | Palo Alto, CA | AI Lab Platform |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Antigenics LLC | , | Now Agenus |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Caris Life Sciences | Irving, TX | Diagnostics |
| VasculoMedics | , | Gone 2019 |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Createrna Science | Wuhan, China | Small Molecules |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| , | Shut down May 2025 | |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Lean Biologix | Norfolk, MA | Consulting |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| , | Website down Dec 2025 - Apr 2026 | |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| BioArctic | Stockholm, Sweden | CNS treatments |
| Trinity Drug Partners | , | Gone |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Emulate | Boston, MA | Organs-on-chips |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| MIFCOR | , | Founders both gone Feb 2021 |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| Paige | New York, NY | AI Pathology |
| Quanticate | Raleigh, NC | Clinical Research |
| Lombard Medical | Didcot, UK | Medical Devices |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Bioquanta | , | Gone 2013 |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| Virco | , | Bought by J&J |
| Apotex | Toronto, ON | Small Molecule Generics |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| OmniGuide | Billerica, MA | Surgical technology |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| AbX Biologics | , | Renamed Abveris |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| ActivaTek | , | Acquired by North Coast Medical |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Bionas Discovery | , | Website gone Jun 2018 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Caidya | Shanghai, China | Clinical Research Organization |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Faze Medicines | , | Shutting down Nov 2022 |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Whole Biome | , | Renamed Pendulum Biosciences |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| , | No news 2020 - Nov 2025 | |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| MicrofluidX | , | Renamed MFX |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Proteintech | Wuhan, China | Research Antibodies |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Wyeth | , | Bought by Pfizer |
| Delpharm | Orléans, France | Contract Manufacturing |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| , | Renamed THX Pharma, Sep 2025 | |
| Akela Pharma | , | Now PharmaForm |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Primevera Therapeutics | , | |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| , | Renamed Mobia Medical, Feb 2026 | |
| Biotrofix | , | Gone, Dec 2014 |
| AstraZeneca | New Haven, CT | Biologics |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| KAI Research | , | Acquired by Navitas Life Sciences |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| Adepthera | , | Shut down 2014 |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| Daktari Diagnostics | , | Gone 2017 |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| Bard1 | , | Renamed INOVIQ |
| Coeptis | , | |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| , | Crypto Pivot, Nov 2025 | |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Zai Lab | Suzhou, China | Small Molecules |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| SegAna | , | Website down May 2021 - Sep 2021 |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| , | Website down Jul 2025 - Dec 2025 | |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Ecopharm | , | Website down Feb 2021 |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| , | Acquired by Frontage, Jul 2021 | |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| , | Acquired by Sartorius, Apr 2025 | |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Bracco | Milan, Italy | Imaging |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| , | Renamed Athens Bioscience, Mar 2026 | |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| tiakis Biotech | Kiel, Germany | Biologics |
| Amorsus | , | Website Gone 8-30-13 |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Altasciences | Everett, WA | Contract Research |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| Endogenx | , | Website Gone Dec 2013 |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| , | Website down Oct 2025 - Feb 2026 | |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Axial Biotech | , | Closed Mar 2013 |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| , | Acquired by Maverix Medical, Dec 2023 | |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| Opentrons | New York, NY | Lab Automation Robots |
| BioMS Medical | , | Gone? |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| Cogenics | , | Now Beckman Coulter Genomics |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Corza Medical | Somerset, UK | Surgical Devices |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| JK Biopharma Solutions | , | Founder gone |
| Creative Enzymes | Shirley, NY | Enzymes |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| EMD Serono | Boston, MA | Biologics |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Tikcro Technologies | , | Liquidating 2021 |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| EPD Biotherapeutics | , | |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| XStalBio | , | Folded |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| Intellimedix | , | Company founder/employee all moved on |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| Synfini | Menlo Park, CA | AI Drug Design |
| Relevant Bio | , | Shut Down Oct 2023 |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| , | Website down Dec 2025 - Apr 2026 | |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Alphatec Spine | , | Renamed Atec Spine |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| Inform Genomics | , | Website Gone Nov 2018 |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| MSD | Ballydine, Ireland | Small Molecules |
| Doloromics | , | Shut down Mar 2025 |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Phytomedics | , | Can't find info on it |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Anergix | , | Shut down Mar 2009 |
| Pevion Biotech | , | Gone, 2-19-14 |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Akubio | , | Bankrupt Sep 2007 |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Nymirum | , | Renamed Base4, Feb 2023 |
| Altus Biologics | , | Vertex Subsidiary |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Metronomia | Munich, Germany | Consulting & Data Management |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| , | Liquidated Jun 2025 | |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| QC Ware | Paris, France | Molecular Discovery Platform |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| Gensco Pharma | Doral, FL | Transdermals |
| , | Shut down Jan 2026 | |
| CovX Research | , | Bought by Pfizer |
| Curium | , | Dissolved, Mar 2015 |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Getinge | Solna, Sweden | Medical Technology |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Evozyne | Chicago, IL | Protein Design Platform |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Medivector | , | Gone late 2018 |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| , | Acquired by Chiesi, Apr 2023 | |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Alvotech | Zurich, Switzerland | Biosimilars |
| accuFD | , | Closed Dec 2017 |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Juno Diagnostics | , | Shut down Jul 2023 |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Epocal | , | Acquired by Alere, Feb 2013 |
| Ignis Therapeutics | Shanghai, China | |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| 4HF Biotec | Freiburg, Germany | Anti-cancer Treatments |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Corin | Cirencester , UK | Orthopedics |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| NKT Therapeutics | , | Shut down May 2021 |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| Celemics | , | Gone Jul 2018 |
| Tella | , | Website down May 2023 - Dec 2023 |
| PreDxion Bio | , | Renamed Refractal |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Piramal | Mahad, India | CDMO |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| OxOnc Development | , | Website gone Apr 2018 |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Abselion | Cambridge, UK | Biologics Quantification |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| Octane Biotech | Lucknow, India | Generics |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Arstasis | , | Appears Gone Sep 2017 |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| Hypromatrix | , | Gone 2007 |
| Allenex | , | Bought by CareDx, Apri 2016 |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Immunogen (1) | , | Renamed ImmunogenX |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Alkermes | Dublin, Ireland | Small Molecules |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| ActoBio Therapeutics | , | Brought into Precigen |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Accellacare | Hickory, NC | Clinical Research |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Celunol | , | Merged with Diversa to become Verenium |
| Cougar Biotechnology | , | Bought by J&J |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Helix | San Mateo , CA | Genetic Testing |
| , | No news 2016 - Sep 2025 | |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| Peritia | Morrisville, NC | Consulting |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Zomanex | , | Gone Oct 2019 |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| , | Website under construction Dec 2024 - May 2026 | |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Vista Scientific | , | Shut down Dec 2015 |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| , | Acquired by Instem, Jul 2025 | |
| Sharp | Hamont-Achel, Belgium | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| NeuroWave Systems | Beachwood, OH | EEG |
| ADispell | , | Website gone Apr 2018 |
| Sea Medical Systems | , | Gone |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| Akesis LLC | , | Bankrupt 2015 |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| BianoGMP | Gera, Germany | Oligonucleotides |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| , | Website down Jun 2025 - Dec 2025 | |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Commave Therapeutics | , | |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| Cellink | Gothenburg, Sweden | Bioprinting |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Scynexis | Jersey City, NJ | Small Molecules |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| GlycoRegImmune | , | Changed name to GRI |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| Niagara Biosciences | , | No info, Aug 2022 |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| ChunLab | , | Renamed CJ Bioscience |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Gilead | Foster City, CA | Small Molecules |
| GeNO | , | Renamed Vero Biotech, 2018 |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| imarc | , | Acquired by Avania, Jun 2021 |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Eisai | Nutley , NJ | Small Molecules |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Microfluidics | Westwood, MA | High shear fluid processors |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Stago | Gennevilliers, France | Diagnostics |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Premier Biomedical | , | Pivoted out of life science |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| SRI International | Menlo Park, CA | Independent Research |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Brighton Biotech | , | Only employee is an accountant |
| Totient | , | Acquired by Absci, Jul 2021 |
| , | Renamed Until Labs, Oct 2025 | |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| LabTwin | , | Merged with Labforward |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| ChronTech Pharma | , | Became real estate company |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Sermes | Madrid, Spain | Full Service CRO |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| Linical | Stuart, FL | Clinical Research |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Dharma Therapeutics | , | Gone, 2013 |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Hutchmed | Hong Kong, China | Oral drugs |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Rhaeos | Evanston, IL | Shunt Monitor |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Advanz Pharma | London, UK | Specialty Generics |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| Rytvel Biotechnology | , | |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| , | Website down Jan 2026 - Mar 2026 | |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| , | Renamed BTgen Bio, May 2026 | |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Kastle Therapeutics | , | Closed May 2018 |
| Ottobock | Vienna, Austria | Prosthetics |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Alkermes | Waltham, MA | Small Molecules |
| Solstice Oncology | , | |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Ufovax | , | Renamed Uvax Bio? |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| iThemba Pharmaceuticals | , | No information |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| Trigemina | , | Shut down Aug 2020 |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| MakroCare | San Francisco, CA | Drug Development Partner |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| ChemPacific | Baltimore, MD | Chemicals |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| , | Website taken over Mar 2026 | |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| BGI | Kobe, Japan | Genetic Testing |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| Proteintech | Manchester, UK | Research Antibodies |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Absynth Biologics | , | Website Gone Jan 2019 |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Brilliant Research | , | Website gone Dec 2018 |
| EPISONA | , | Gone Nov 2018 |
| ProtAffin | , | Winding Down |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Synosia Therapeutics | , | Acquired by Biotie |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Defyrus | , | Website gone Nov 2017 |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| GTX Medical | , | Renamed ONWARD |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| QT Ultrasound | , | Renamed QT Imaging |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| Cellenion | Lyon, France | Single Cell Testing |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| , | Website down Aug 2025 - Jan 2026 | |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| DNAMx | , | Renamed Adela |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| , | Winding down Apr 2026 | |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Flownamics | Madison, WI | Automated Sampling |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| SunMed | , | Renamed AirLife |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Pneumolabs | , | Dissolved Sep 2018 |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Affinimark Technologies | , | Gone |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Heraeus Medical | Dorado, PR | Medical Devices |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| Vesper Medical | Wayne, PA | Venous Stent |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| Compass Biotech | , | Defunct |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| Provecs Medical | , | Gone Nov 2019 |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| DDi | London, UK | Clinical Software |
| Ciphergen | , | Now Vermillion |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| Affitech | , | Gone |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Iconovo | Lund, Sweden | Inhalation Technology |
| , | Merged into Meridian Bioscience | |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Dropshot Therapeutics | , | |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Bruker | Billerica, MA | Scientific Instruments |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| Torpedo Bio | , | |
| Memento Medicines | , | |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| ReactDx | Melbourne, FL | Wireless Monitors |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Genera Medix | , | Apparently sold all products |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Gene ID inc | , | Website taken over |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| Stryker | Mahwah, NJ | Medical Devices |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| , | Website down Jul 2025 - Dec 2025 | |
| Cytiva | Piscataway, NJ | Medical Devices |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Leading Pharma | Fairfield, NJ | Generics |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| Nusano | Valencia, CA | Radioisotopes |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Cordis | Miami Lakes, FL | Medical Devices |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| MantaBio | Beverly, MA | Real-time PCR System |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| Xyntek | , | Segment of non-life science business |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Makefield Therapeutics | , | Website Gone |
| , | Website down Oct 2025 - Feb 2026 | |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Mologen | , | Liquidating, May 2020 |
| Getinge | Antalya, Turkey | Medical Technology |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Gossamer Bio | San Diego, CA | Small Molecules |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Trophea Development | , | Liquidated Dec 2019 |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Novotech | Hong Kong, China | Clinical Research |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Biotagenics | , | Renamed MedBiome |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Pharmaron | Beijing, China | R&D Services |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| QuatRx | , | Acquired by Shionogi, 2017 |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| , | Website down Dec 2025 - Apr 2026 | |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| GenturaDx | , | Bought by Luminex 2012 |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Selventa | , | Closed 2016 |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| CenterVue | , | Merged into iCare, Apr 2020 |
| , | Renamed FocalOne, Feb 2026 | |
| AMRI | , | Renamed Curia, Jul 2021 |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| , | No news 2019 - Sep 2025 | |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Menarini | Florence, Italy | Biologics |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| VG Life Sciences | , | Shell company |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Personalis | Fremont, CA | Genome Services |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Kurin | San Diego, CA | Blood Collection Technology |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Optovue | , | Renamed Visionix Sep 2021 |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| Immunovant | Durham, NC | Monoclonal Antibody |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| Ipsen | Wrexham, UK | Biologics |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| Balboa Biosciences | , | Gone 2010 |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| Accugent Laboratories | , | Website gone Sep 2017 |
| August Therapeutics | , | Shut down Dec 2024 |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| Gangagen | Bangalore , India | Ectolysins |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| ImmuNext | , | Website gone Feb 2025 |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| CombiGene | , | Stopped research Jan 2025 |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| Medicure | Holetown, Barbados | Small Molecule |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| One Drop | , | Gone Dec 2024 |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| Nile Therapeutics | , | Merged with Capricor |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Metrad Biosystems | , | Website gone |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Genfit | Cambridge, MA | Drug Discovery |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| Grove Instruments | , | Shut Down June 2017 |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Multerra Bio | , | Bankrupt May 2021 |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| , | Website taken over Mar 2026 - Apr 2026 | |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| Heraeus Medical | Changshu, China | Medical Devices |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| G6 Spine | , | Gone 2017 |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Knopp Biosciences | , | |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Cambridge Pharma | , | Rolled into parent, SMC |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Crown Bioscience | Taicang, China | Drug Development |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| OD-OS | Teltow, Germany | Retinal Laser |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| Zelos Therapeutics | , | No site |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Innovative BioTherapies | , | Gone |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Velia Therapeutics | , | Shut down Jan 2025 |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| Novelty Nobility | Seongnam, Korea | ADCs |
| hVIVO | London, UK | Viral Services |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Aerovance | , | Gone, don’t know where |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Y's Therapeutics | , | Website Gone |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Best Vascular | , | Now Best Vascular Novoste |
| Celsense | , | Shut down Dec 2021 |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| Sharp | Allentown, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Stasys Medical | , | Shut down Feb 2025 |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Pall | Port Washington, NY | Filtration |
| Enlibrium | , | Gone 2018 |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| TRPblue | , | Shut down Dec 2023 |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| Ortho Development | Draper, UT | Ortho Implants |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| Piramal | Aurora, ON | CDMO |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Greppo Technologies | , | Renamed Verix Health |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| OmniBiome Therapeutics | , | Gone 2014? |
| NX Development | Lexington, KY | Brain Imaging |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| Occam Design | Louisville, SS | Medical Device Development |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Dipharma | Baranzate, Italy | APIs, Generics |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Synovex | , | Renamed Adheron Therapeutics |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| , | Acquired by IQVIA | |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| GeneSeek | , | Bought by Neogen |
| Piramal | Sellersville, PA | CDMO |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| , | Winding down Jan 2026 | |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| SYNkinase | , | Shut down |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Septerna | South SF, CA | GPCR Drug Discovery |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Piramal | Riverview, MI | CDMO |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| Spherics | , | Bankrupt |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Eminent Services | Frederick, MD | Drug Services |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Hovione | Osaka, Japan | Contract Manufacturing |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| Ottobock | Duderstadt, Germany | Prosthetics |
| Clarivate | London, UK | Vascularized organoids |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Nesher Technologies | , | Shut down Oct 2017 |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| SFS | Madrid, Spain | Clinical Research Organization |
| Nanosens | , | Merged into Cardea Oct 2019 |
| , | Shut down Jan 2025 | |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Biotrin International | , | Renamed Diasorin? |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Global Cell Solutions | , | Gone Apr 2018 |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Alimentiv | San Diego, CA | Clinical Services |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Norgine | Hengoed, UK | Specialty Pharma |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| Omniseq | , | Acquired by LabCorp, 2021 |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| EcoSurg | , | Shut Down May 2017 |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| F2G | Cheshire, UK | Antifungals |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Amplyus | , | Renamed miniPCR |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| 3DBiopsy | , | Renamed Triopsy |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Neuro3 Therapeutics | Cambridge, | Small Molecules, siRNA |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Loop Therapeutics | , | Shut down Jan 2021 |
| MEDISPECTRA | , | Gone 2002 |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| Haini Pharmaceutical | Shanghai, China | Generics |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| Celerion | Vienna, Austria | Clinical Research |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| , | Website down Jul 2025 - Oct 2025 | |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| Centinel Spine | West Chester, PA | Spinal Implants |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Endologix | Irvine, CA | Medical Devices |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| EndoLogic | , | Seems inactive, Aug 2023 |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| , | No news 2019 - Jan 2026 | |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| , | Renamed Peritia, Jan 2026 | |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Scinomix | Earth City, MO | Lab Automation Products |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| Vision Medicines | , | Gone 2017 |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Medica | , | Gone before 2019 |
| Nano Science | , | Acquired by EAG, 2006 |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| , | Acquired by Olon, 2024 | |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| , | CEO left 2020, still on website Dec 2025 | |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Ennov | Paris, France | Software Solutions |
| Polpharma | Starogard Gdanski, Poland | Generics |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Novogene | Beijing, China | Genomic Services |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| Genomic Solutions | , | Acquired by Digilab |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Logan Medical Devices | , | Gone? |
| iCareDx | , | Renamed AcuamarkDx |
| Yao Pharma | Chongqing, China | APIs, Generics |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| Panther Orthopedics | , | Shut down Dec 2022 |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Axcend | Lehi, UT | Chromatography Services |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| , | Website down Jan 2026 - Apr 2026 | |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| , | Website down Dec 2025 - Apr 2026 | |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Diverse Genomics | , | Website gone Jul 2020 |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Apofore | , | Shut down, Dec 2015 |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Getinge | Ankara, Turkey | Medical Technology |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Reserva | , | Renamed NeurMedix, 2016 |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| , | Website down Jul 2025 - Dec 2025 | |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| , | Renamed Kapadi, Nov 2025 | |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Znomics | , | Bankrupt, Shell Company Now |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Hua Medicine | Shanghai, China | Small Molecules |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| RecomGenex | , | Renamed TargetEx Biosciences |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| Green Cross | , | Renamed GC Pharma |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| , | Renamed Cyaris, Apr 2026 | |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Sonavex | Baltimore, MD | Ultrasound |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Aspira Scientific | , | Gone Nov 2015 |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| LightMed | , | |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Cell Biosciences | , | Now ProteinSimple |
| Vivifi Life Sciences | Bangalore, India | Generics |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| La Jolla Biologics | , | Website gone Nov 2014 |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| MGI Tech | Shenzhen, China | Sequencing |
| EVerZom | Paris, France | Exosome Therapeutics |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| , | Website down Oct 2025 - Feb 2026 | |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Novahep | , | Website down, Oct-Dec 2017 |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| Catylix | , | Shut down Oct 2021 |
| Senseonics | Germantown, MD | Medical Devices |
| BioAMPS | , | Gone |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Profil | Neuss, Germany | Clinical Research Services |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Skylit Medical | , | Renamed Clarify medical |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| , | Website down Jul 2025 - Dec 2025 | |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Assay Designs | , | Now Enzo Life Sciences |
| Sania Therapeutics | London, UK | CNS Treatments |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| Evogene | Rehovot, Israel | Computational Biology |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| NeuroVasx | , | No website May 2019, founded 1997 |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Revvity | Boston, MA | Diagnostics, Services |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| GeneFab | Alameda, CA | Gene Therapy Services |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Avioq | Durham, NC | HIV Diagnostics |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | No news 2021 - Sep 2025 | |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| SomaLogic | Boulder, CO | Blood Analysis |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Cytheris | , | Out of business 2013 |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Arxspan | , | Renamed SciY |
| , | Renamed Verge Medical, Mar 2025 | |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Bioventus | Cordova, TN | Orthobiologics |
| AccelaPure | , | Bankrupt 2007 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| , | Renamed ExGen Dx, Jul 2025 | |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| , | Renamed Racura Oncology, Dec 2025 | |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| Avontec | , | Gone |
| Tecnimede | Lisbon, Portugal | Generics |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| Allez Health | Carlsbad, CA | Biosensors |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Hematogenix | Tinley Park, IL | Pharma Services |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| Quantificare | Biot, France | Medical Imaging |
| Mattson Jack | , | Now Kantar Health 2009 |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Azano Biotech | , | Now Sandia Biotech |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| , | Website down Jan 2026 - May 2026 | |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Urogenix | , | Acquired by Astellas |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| Ambu | Ballerup, Denmark | Medical Devices |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| Phenoquest | , | Website gone, Oct 2015 |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| Pfizer | Kalamazoo, MI | Manufacturing |
| Altos Therapeutics | , | Gone Jun 2019 |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| Sopherion | , | Website taken over, Mar 2017 |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| NIOX | Oxford, UK | Asthma management device |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| , | Renamed Envue, Feb 2026 | |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Catalent | Winchester, KY | Contract Manufacturing |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| Libra Clinical Research Associates | , | Gone |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Synairgen | Southampton, UK | Inhaled Biologics |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Amoytop Biotech | Xiamen, China | Biologics |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| ViaCord | , | Part of PerkinElmer |
| Evvy | New York, NY | At-home vaginal microbiome test |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Accelrys | , | Bought by Dassault, 2014 |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| Biocodex | Gentilly, France | Microbiota Treatments |
| Aplagen | , | No activity since 2008 |
| Vivacy | Archamps, France | Aesthetic Medicine |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Genfit | Loos, France | Drug Discovery |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Alper Biotechnology | , | Gone |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| NeoPharm | , | Merged with Insys Therapeutics |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| , | Renamed Numerion Labs, Oct 2025 | |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| , | Acquired by Collate, Aug 2025 | |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| Alexis Biotech | , | Dissolved May 2015 |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| Champions Biotechnology | , | Now Champions Oncology |
| Organix | Woburn, MA | Contract Research & Development |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Signatur Biosciences | London, UK | PCR Platform |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| Eurosequence | , | Website gone Jan 2020 |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| BEAT BioTherapeutics | , | Closed 2017 |
| United Immunoassay | , | Business revoked Jan 2022 |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| BioCrea | , | Website Gone, Feb 2018 |
| Getinge | Plewiska, Poland | Medical Technology |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| 121 Bio | , | Gone mid 2016 |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| Exelixis | Alameda, CA | Small Molecules |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| Cell Genesys | , | Merged with BioSante |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| MeiraGTx | London, UK | Gene Therapy |
| Spiden | , | Renamed Liom, Jul 2024 |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Kar Bioanalytical | , | Seem gone |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| United Neuroscience | , | Renamed Vaxxinity |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| Akrivis Technologies | , | Gone Jun 2021 |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| , | Website down Dec 2025 - Apr 2026 | |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Phasiq | , | Website gone Jul 2018 |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Medtronic | Mounds View, MN | Medical Devices |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| CBM Biopharma | , | Shut down Nov 2020 |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Synomics | , | Now Smithers Pharma Services |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| , | Website down Nov 2025 - Apr 2026 | |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| Aadigen | , | Renamed Aanastra |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Tigris Pharmaceuticals | , | Now Kirax |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| Rgene | , | Late business filings Aug 2021 |
| APCRA | , | Shut down 2020 |
| MSD | Carlow, Ireland | Vaccines |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| , | Website down Oct 2025 - Feb 2026 | |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| AerovectRx | , | No news since 2006, Website gone |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| , | Website down Oct 2025 - Feb 2026 | |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| AlloCure | , | Website Gone, Jul 2015 |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| Neoantigenics | , | Website gone Sep 2017 |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| Biopar | , | Gone? |
| T&T Scientific | , | Website gone May 2023 |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| UMN Pharma | , | Liquidating Apr 2025 |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| PeriGen | Cary, NC | Perinatal Devices |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| RION | Rochester, MN | Exosome Therapeutics |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Velquest | , | Bought by Accelrys Jan 2012 |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Affymax | , | Dissolved 2014 |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Medrio | San Francisco, CA | Clinical Trial Software |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| OXON | Madrid, Spain | Real World Evidence |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Blu Biotech | , | Website down May 2023, CEO gone |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Genomas | , | Website gone May 2020 |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Parexel | Durham, NC | Clinical Research |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| Cureport | Worcester, MA | Nanomedicines |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| , | ||
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| , | Acquired by HiRO, Aug 2023 | |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Pinnaxis | Noida, India | Pharmacovigilance |
| , | Acquired by Instem, Jul 2025 | |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| , | Website down Dec 2025 - Apr 2026 | |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Pharmaron | Hertfordshire , UK | R&D Services |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| OBDURO Biotechnologies | , | never a registered CA business |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| CanSino Biologics | Tianjin, China | Vaccines |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Gastrotech | , | Now Rose Pharma |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Omneuron | , | Closed |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Afaxys | Charleston, SC | Women's Health |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Biotheneum | , | Gone |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| bioTHER | , | Gone |
| Calyx Pharma | Mumbai, India | APIs |
| Tuevol Therapeutics | , | Gone by 2020 |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Catamaran Bio | , | Winding down Jan 2024 |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| ProPharma Group | Raleigh, NC | Consulting |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| , | Acquired by IQVIA | |
| Biohit | Helsinki, Finland | Diagnostics |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| Blue Cross Laboratories | Mumbai, India | Generics |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| JustRight Surgical | , | Renamed Bolder Surgical |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Phase Forward | , | Bought by oracle |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| , | Winding down Apr 2026 | |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| MicroPort | Clamart, France | Medical Devices |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Laborie | Portsmouth, NH | Medical Devices |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| GL Technologies | San Diego, CA | Calibration Services |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| Annova Chem | , | Gone, 2017 |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| Transdermal Technologies | , | Website Gone |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| , | Renamed Cytonome, Jul 2003 | |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| , | Gone Jan 2026 | |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| PPL Therapeutics | , | Sold in 2003 |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Nova Biomedical | Norwood, MA | Lab instruments |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| MabSpace Biosciences | , | Renamed Transcenta |
| Anoixis | Natick, MA | Pharmacometric Services |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| ProPharma Group | Fort Washington, PA | Consulting |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| , | Website down Jul 2025 - Dec 2025 | |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| , | Website down Nov 2025 - Apr 2026 | |
| Epigen | , | Renamed Egenix, 2002 |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| Calico | South SF, CA | Aging treatments |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Nanovelos | , | Subsumed into Nanogroup |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| Affivant | , | Part of Roivant |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| FFE Therapeutics | , | Shut down Dec 2013 |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| Lunit | Seoul, Korea | AI Image Analysis |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| Apoptos | , | Acquired by Receptos |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| Genaera | , | Dissolved |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| , | Winding down, Dec 2025 | |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| , | Acquired by Tecan, Aug 2021 | |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| SourceMDx | , | Assets Sold |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Maccine | , | Gone |
| , | Website down Oct 2025 - Feb 2026 | |
| Adynxx | , | Website taken over Sep 2020 |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| Indago | , | Renamed Lazurite |
| Metrohm | Houston, TX | Lab Data Management Software |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Monobind | Lake Forest, CA | IVD |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| Cogentis Therapeutics | , | No news 2017-2023 |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| VentriFlo | Pelham, NH | Blood Pumping System |
| DDi | Singapore, Singapore | Clinical Software |
| Altasciences | Cypress, CA | Contract Research |
| AlcaSynn | , | Renamed ChironWells |
| Rezolute | Redwood City, CA | Biologics |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Pharmexon | Prague, Czech Republic | Consulting |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| Viropro | , | Bankrupt 2015 |
| , | Acquired by Instem, Jul 2025 | |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| AntiOp | , | Tech sold Jun 2015 |
| Keenova | Bridgewater, NJ | Small Molecules |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Almirall | Barcelona, Spain | Small Molecules |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Veeva Systems | Toronto, ON | Life Science Software |
| Nanostream | , | Closed Mar 2008 |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| , | Became part of Accelerator, Dec 2025 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Rezolute | Bend, OR | Biologics |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| Tirupati | New Delhi, India | Generics |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| Curamir Therapeutics | , | Shut down 2020 |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Protein Design Labs | , | Renamed PDL Biopharma |
| Transcend Therapeutics | New York, NY | Psychedelics |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| , | Website down Dec 2025 - May 2026 | |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Safecor Medical | , | Shut down Apr 2021 |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Accutome | , | Now part of Keeler |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| VaxNewMo | , | Renamed Omiose |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Targanta | , | Bought by The Medicines Company |
| Athlon Pharma | , | No news since 2006 lawsuit |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Kerecis | Arlington, VA | Wound Healing |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| InVasc Therapeutics | , | Shut down 2012 |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| BioMarin Pharmaceutical | London, UK | Biologics |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Calchan | , | Shut down Dec 2020 |
| VB Spine | Allendale, NJ | Spinal Implants |
| Excalipoint Therapeutics | Shanghai, | |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Metamark Genetics | , | Shut down 2018 |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Promedior | , | Acquired by Roche, Feb 2020 |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| SironRx | , | Website gone Jul 2015 |
| Qbiogene | , | No website. Fisher sells their products |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| Advanced Peptides | , | No business filings since 2011 |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Cellworks | South SF, CA | Biosimulations |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| Jina Pharmaceuticals | , | |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| Octant Biotech | Emeryville, CA | Small Molecules |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Advaned Viral Research | , | Shut down 2009 |
| TFS | Lund, Sweden | Clinical Research |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| , | Acquired by Immedica, Feb 2025 | |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| PLC Medical Systems | , | Renamed RenalGuard |
| Medtronic | Cincinnati, OH | Medical Devices |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| SulfaGENIX | , | Website gone, Jan 2019 |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| Quratis | Cheongju, Korea | Vaccines |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| , | Website down Dec 2025 - Apr 2026 | |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Nura Bio | South SF, CA | Small Molecule |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| Admescope | Oulu, Finland | ADME-tox services |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| STB Lifesaving Technologies | , | Website gone |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| AccuVein | Medford, NY | Vein Visualization |
| ARTham Therapeutics | , | Shut Down late 2023 |
| BioWa | , | Part of Kyowa Kirin Group |
| , | Website down Jan 2026 - Mar 2026 | |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Cytera CellWorks | , | Renamed Mytos |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Cellenion | Berlin, Germany | Single Cell Testing |
| InterGenetics | , | Assets auctioned |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| CytoLogix | , | Gone, Sep 2012 |
| Angiosonics | , | Shut down 2002 |
| UniXell | Shanghai, China | Cell Therapy |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| Vivex Biologics | Atlanta, GA | Tissues |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| , | Website taken over, Jan 2026 | |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Novacea | , | Bought by Transcept |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| NovaLead Pharma | Pune, India | Small Molecules |
| Bach Pharma | , | Shut down late 2023 |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| , | Pivoted to food, Feb 2026 | |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| BioTeam | Middleton, MA | Scientific IT consulting |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Abbott | Des Plaines, IL | Diagnostics |
| , | Shut down Dec 2025 | |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| LexaMed | Toledo, OH | Life Science Consulting |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| GT Molecular | Fort Collins, CO | PCR Kits |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Ansh Labs | Webster, TX | Diagnostics Products |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Circadiance | Export, PA | CPAP Mask |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Barrier Therapeutics | , | Bought by Stiefel |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| TransGenRx | , | Bankrupt |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| Heritage Pharmaceuticals | , | Part of Emcure |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Genecare | , | Gone |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| SeqRight | , | Acquired by GE Apr 2012 |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| , | Seems inactive Jan 2026 | |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Persomics | , | Gone 2019 |
| , | Acquired by InformedDNA, Mar 2025 | |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| Bridge Laboratories | , | Gone 2013 |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| Pentapharm | Basel, Switzerland | APIs |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| , | Acquired by mining company; fka Anew Medical | |
| BioConsulting International | , | Ancient website, presumed defunct |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| AstronauTx | London, UK | Alzheimer's Treatments |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Nycomed | , | Acquired by Takeda 2011 |
| AsymBio | Jinshan, China | Biologics CDMO |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Librede | , | Acquired by Lygos, Jan 2020 |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| EpitoGenesis | , | Gone 2017 |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Fortrea | Durham, NC | Clinical Research |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| Madeira Therapeutics | , | Gone. No info |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| Celerion | Tempe, AZ | Clinical Research |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| , | Website down Sep 2025 - Dec 2025 | |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| , | Website down Jan 2026 - May 2026 | |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| Kuano | Cambridge, UK | AI Drug Discovery |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| , | Acquired by Instem, Jul 2025 | |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| Allelix | , | Merged with NPS |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| Vasade Biosciences | , | Gone |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| Biomax Informatics | , | Acquired by Labvantage |
| Genta | , | Liquidation 2012 |
| Empatica | Milan, Italy | Seizure Detection |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| Aves Labs | , | Now part of Antibodies Inc |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| Sanarus | , | Acquired by Hologic, 2020 |
| Gilead | Oceanside, CA | Small Molecules |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Boston Scientific | St. Paul, MN | Medical Devices |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| Genemod | Edmonds, WA | Lab management software |
| Gerard Biotech | , | Lab supplies, seems defunct |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Vision Genomics | , | Website Gone, Jul 2016 |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Envision Pharma | , | Merged with UBC |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| , | Liquidating, Sep 2025 | |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Getinge | Delft, Netherlands | Medical Technology |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Surgisense | , | Presumed gone |
| Acumed | Madrid, Spain | Medical Implants |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Insulete | , | Website gone, presumed inactive |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| Novian Health | Evry, France | Device for breast tumor ablation |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| Analog Pharma | Princeton, NJ | Generics |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| , | Website down Dec 2025 - Jun 2026 | |
| Semaphore Solutions | Victoria, BC | Lab Software |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Noble | Orlando, FL | Auto-injector Trainers |
| PRACS Institute | , | Bankrupt 2013 |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Osivax | Lyon, France | Universal Flu Vaccine |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| NextCure | Beltsville, MD | Immune Therapies |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Immagene | , | Renamed Flindr Therapeutics |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Diamed | , | Bought by Bio-rad |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| Novotech | Sydney, Australia | Clinical Research |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| , | Renamed Create Medicines, Oct 2025 | |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| , | Website down May 2025 - Dec 2025 | |
| BrainCells | , | Website gone Feb 2014 |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| Rubicon Research | Thane , India | Generics |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Rox Medical | , | Gone 2019 |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| Bellus Medical | , | Renamed Crown Aesthetics |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Carver Biosciences | , | |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Genesis Imaging Services | , | Renamed Pharmanest |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Glenmark | Mumbai, India | Generic Small Molecules |
| , | Acquired by Source BioScience, Apr 2025 | |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| Xeris Biopharma | Chicago, IL | Injectables |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Angiomics | , | Product being sold by another company |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Harmony Labs | , | Now Ei |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Agile EndoSurgery | , | Gone |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| , | Website down Jul 2025 - Dec 2025 | |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Amplifold | , | DNA origami nanotechnology |
| Sancilio | , | Now Micelle BioPharma |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| Avant Immunotherapeutics | , | Merged with Celldex |
| , | Website down May 2025 - Dec 2025 | |
| Vaccibody | , | Renamed Nykode Therapeutics |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Angel Biotechnology | , | Bankrupt, 2013 |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| Modular Medical | San Diego, CA | Insulin Pump |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Biowest Therapeutics | , | Website Gone |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Newgen Biopharma | , | Suspended trading due to scandal |
| MSD | Brinny, Ireland | Small Molecules |
| Lupin | Mandideep, India | Generics |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| ProteoVec | , | Website gone Jul 2015 |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Teva | West Chester, PA | Small Molecules |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| CBH ClinTrials | , | now CenExelCBH |
| Gamma Therapeutics | , | Gone |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Biomoles | , | Closed Sep 2017 |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| BA Sciences | Morrisville, NC | Analytical Services |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| NextPharma | London, UK | Contract Research & Development |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| LinaTech | Suzhou, China | Cancer treatment device |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| preclinics | Eystrup, Germany | Contract Research |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| Itero Biopharmaceuticals | , | Website Gone |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| GeneEx | , | Now RevDia |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| ViroMed | , | Renamed Helixmith |
| , | Website down Jan 2026 - May 2026 | |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| BIND Biosciences | , | Now BIND Therapeutics |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| , | Acquired by Eclipsebio, Jan 2026 | |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| Interdict | San Francisco, CA | Small Molecules |
| HeartVista | , | Renamed Vista.ai |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| Synostics | , | Gone 2014 |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Onkor Pharma | , | 10 year old company with no product or website |
| Anavex Life Sciences | New York, NY | Small Molecules |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| TR Biosurgical | , | Website Taken Over |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Grunenthal | Aachen, Germany | Small molecules |
| Pharos iBT | , | aka Pharos iBio |
| NeuroVia | , | Shut down 2019 |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| RetiPharma | , | Dissolved Nov 2019 |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| SOCIUM | Tokyo, Japan | Contract Research |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Hybrigenics Services | , | Renamed ATON Group |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Spring Discovery | , | Renamed Spring Science |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Esper Therapeutics | , | Shut down 2016 |
| Ergomed | Raleigh, NC | Clinical Research |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Labopharm | , | Bought by Paladin 2011 |
| Viravaxx | , | |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Delpharm | Milan, Italy | Contract Manufacturing |
| GenoMatix | , | Acquired by Intrexon |
| Nuvelution Pharma | , | Gone 2020 |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| MiRus | Marietta, GA | Spine Implants |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| InxMed | Beijing, China | Oncology Treatments |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Duramed | , | Acquired by Barr Labs 2001 |
| Xact Medical | , | Website down Mar 2024 |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Mentrik Biotech | , | Gone |
| , | Renamed Fareon, Feb 2025 | |
| Kallyope | New York, NY | Gut-brain axis focus |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Flen Pharma | , | Now Flen Health |
| , | Website down Oct 2025 - Feb 2026 | |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Kura Oncology | San Diego, CA | Small Molecules |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| Altravax | , | Shut down 2016 |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Monroe Research | Monroe, NC | Clinical Trials |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| CONMED | Largo, FL | Surgical, Medical Devices |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Neuron23 | South SF, CA | AI-drug discovery |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Nya Cell Therapeutics | , | No info |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Oncogen | , | Acquired by BMS, 1986 |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| Twistnostics | , | Renamed Scanogen |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Dynacare | , | Bought by LabCorp 2002 |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| Genialis | Boston, MA | Bioinformatics |
| Iomai | , | Bought by Intercell 2008 |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Islet Sciences | , | Gone |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| Attralus | Naples, FL | Amyloidosis Treatments |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| Nteryx | , | Changed name to Ardelyx |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Bafna | Chennai, India | Generics |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| GlycoSolutions | , | Closed Aug 2015 |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| Getinge | Englewood, CO | Medical Technology |
| , | Acquired by IQVIA | |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| Helsinn | Iselin, NJ | Small Molecules |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Ribopro | Oss, Netherlands | mRNA Services |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Integrated Genomics | , | Changed to Igenbio |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| Bioserv America | , | Shut down Aug 2024 |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Mousera | , | Renamed Vium |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Cell>Point | , | Cant find any confirmation they are active |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| , | Gone Mar 2024 | |
| Clinisys | Tucson, AZ | LIMS Platform |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Modern Biosciences | , | Renamed Istisso |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| Formex | , | Merged into BioDuro, Nov 2015 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| , | Website down Jul 2025 - Dec 2025 | |
| Avomeen | , | Acquired by Element, Mar 2021 |
| 2 Bridge | Zoersel, Belgium | Consulting |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| Genencor | , | Bought by DuPont |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| LC Technologies | , | Renamed EyeGaze |
| Norgine | Madrid, Spain | Specialty Pharma |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| MedGyn Products | Westmont, IL | OBG Devices |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| PRI Research | , | Renamed Wake Clinical |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Sopharma | Sofia, Bulgaria | Generics |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Solexa | , | Merged with Illumina 2006 |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Dante Labs | , | Seems to be Dante Genomics now |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| , | Acquired by Novacyt Group | |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| Soluble Systems | , | Renamed Solsys Medical |
| Alerchek | , | Closed late 2016 |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Aegea Biotechnologies | , | |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| , | Renamed Ribonexus, Nov 2021 | |
| Resilience | Mississauga, ON | Biomanufacturing |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| Alverix | , | Acquired by BD, Jan 2014 |
| MakroCare | Princeton, NJ | Drug Development Partner |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Lupin | Maharashtra, India | Generics |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Antios Therapeutics | , | Shut down Feb 2023 |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| APIE Therapeutics | , | Gone Jun 2025 |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| argenx | Boston, MA | Antibody therapies |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| , | Website down Jan 2026 - May 2026 | |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| Ocis Biotechnology | , | |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Niowave | Lansing, MI | Radioisotopes |
| , | Website down Dec 2025 - Jun 2026 | |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Getinge | Merrimack, NH | Medical Technology |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| NetBio | , | Renamed ANDE |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Proteologics | , | Apparently Gone |
| EhmetDx | , | Renamed Ehmet Health |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Corza Medical | Boulder, CO | Surgical Devices |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| , | Merged with Nova Biomedical | |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Mott | Farmington, CT | HPLC system components, Filtration |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| Anesiva | , | Bankrupt 2010 |
| Amarin | Dublin, Ireland | Small Molecules |
| Curadev | Kent, UK | Immuno-oncology |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Abbott | Alameda, CA | Diabetes Care |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Michrom | , | Bought by Bruker, Feb 2011 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| , | Acquired by MannKind, Oct 2025, $296M | |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| RegeneMed | , | No longer active in CA as of 2014 |
| Parker BioConsulting | , | Sole employee is a professional board member |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Medarex | , | Bought by BMS 2009 |
| Savage Medical | , | Renamed Averto Medical |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Assets Acquired by Klotho, Sep 2025 | |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Fluoxivid Diagnostics | , | Single person company with no location |
| AmCell Biosciences | , | Website gone Apr 2021 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Movetis | , | Acquired by Shire, Aug 2010 |
| CelerDx | , | Tiny startup that went nowhere |
| Delpharm | Reims, France | Contract Manufacturing |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| AdipoGenix | , | Gone Jun 2012 |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Atlas Genetics | , | Renamed Binx Health |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| Sanofi | Midrand, South Africa | Biologics |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Drugabilis | Villejust, France | Druggability Services |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Hovione | Loures, Portugal | Contract Manufacturing |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| HawkCell | Lyon, France | MRI Research Technology |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| VastBiome | , | Renamed PragmaBiome |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Altasciences | Laval, QC | Contract Research |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| , | Acquired by Syner-G BioPharma Group | |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| NTC | Milan, Italy | Generics |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| , | Website down Sep 2025 - Feb 2026 | |
| , | Website down Nov 2025 - Feb 2026 | |
| Gataca | , | Gone |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Ossur | Irvine, CA | Orthopedic Devices |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Diagast | Loos, France | Transfusion Reagents |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Cytomatrix | , | Gone, Jun 2013 |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Qynapse | Boston, MA | Imaging Analysis |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| IvWatch | Newport News, VA | IV infiltration detection |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| AndroBioSys | , | Presumed gone |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| US Genomics | , | Now PathoGenetix |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Gencove | New York, NY | Genome Sequencing |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Bio Processing | , | Bought by Bio-rad |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Phoresa | , | Shut down Mar 2018 |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| GlySens | , | Bankrupt Nov 2022 |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| Artera | Los Altos, CA | AI Diagnostics |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| AndroScience | , | Ancient website, no news 2014-2023 |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| DKP Genomics | , | Dissolved Jul 2025 |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| Abogen | Suzhou, China | mRNA |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| M2 Medical | , | Now Asante Solutions |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Gerinda Therapeutics | , | Gone 2009 |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| Simondr | , | Website gone, President has new job |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Nanogen | , | Now Epoch Biosciences |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Lacerta Therapeutics | , | Shut down May 2024 |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| MiniVax | , | Gone Jan 2016 |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Intelligent MDx | , | Shut down, Feb 2015 |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Idience | Seoul, Korea | Cancer Therapies |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Neotech | , | Website down Jan 2019 |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| DM Clinical Research | Houston, TX | Clinical Research |
| ChondroGene | , | Now GeneNews |
| SDIX | Newark, DE | Diagnostics |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Genoma | , | Website gone May 2021 |
| JD Bioscience | Seoul, Korea | Small Molecules |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Tensys Medical | , | Website gone Sep 2017 |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| Avexxin | , | Rebranded as Coegin Pharma |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Remo CRO | , | Seems to be rebranded as Supeira |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| Cyberval | , | Seems inactive Feb 2024 |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Virometix | Schlieren, Switzerland | Vaccines |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Medion Diagnostics | , | Bought by Grifols? |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| KXT bio | , | Shut down 2019 |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Cygene Labs | , | Gone |
| Elypta | Solna, Sweden | Liquid Biopsy |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Aspreva | , | Acquired by Vifor Pharma |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| , | Renamed Virchow | |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Medtronic | North Haven, CT | Medical Devices |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Genomics | Oxford, UK | Human Genetics Platform |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| , | Website down Jan 2026 - Mar 2026 | |
| , | Selling pipeline, winding down Jul 2025 | |
| , | Website down May 2025 - Dec 2025 | |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Abcam | Waltham, MA | Antibodies |
| Ipca Laboratories | Mumbai, India | APIs |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Elanex Pharmaceuticals | , | Gone |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| Lung LLC | , | Renamed Lung Biotechnology |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Grannus Biosciences | , | Gone |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| , | Acquired by StarFish Medical, Nov 2024 | |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| Virvio | , | Gone Feb 2020 |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Balance Therapeutics | , | Gone late 2020 |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| , | Pivoted to defense contracting, Jan 2026 | |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Merck KGaA | Singapore, Singapore | Small Molecules, Purification Equipment, etc. |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Actis Biologics | , | Gone |
| Patronus Biotech | Singapore, | |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| MicroVention | , | Now Terumo Neuro |
| , | Website 404 Sep 2025 - Apr 2026 | |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Tactic Pharma | , | Website gone, Apr 2018 |
| Ribomic | Tokyo , Japan | Aptamers |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Forge Biologics | Grove City, OH | Biologics |
| 89bio | San Francisco, CA | Liver Treatments |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Stryker | Flower Mound, TX | Medical Devices |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Chromocyte | , | |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| Apieron | , | Shut down, May 2010 |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| Cira Discovery | , | Website copyright 2003 |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Genestack | Cambridge, UK | Genomics operating system |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Extract Technology | Mauston, WI | Containment Equipment |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| Clina Research | , | Website gone Jul 2023 |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Uncover Therapeutics | , | |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Comac Medical | Sofia, Bulgaria | European CRO |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Diatos | , | No website, founded 1999 |
| Ergomed | Prague, Czech Republic | Clinical Research |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| , | Website down Dec 2025 - Apr 2026 | |
| Avistone | Beijing, China | Precision Oncology |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Micell Technologies | , | Seems shut down 2019 |
| Oxitope | , | Shut Down Feb 2019 |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Genedata | Basel, Switzerland | Bioinformatics |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| , | Pivoted to crypto Jan 2026 | |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| Kuroki Consulting | , | Shut down 2020 |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| , | Crypto Pivot, Oct 2025 | |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| Proveri | , | Gone 2016 |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| Neurophet | Seoul, Korea | AI-Image Processing |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Cellink | Blacksburg, VA | Bioprinting |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| MicroCam | , | Shut down 2015? |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Venta Medical | , | Gone, Apr 2017 |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| RJS Biologics | , | Shut down Feb 2019 |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| NeoTrail Therapeutics | , | |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| Sebra | Tucson, AZ | Tube Sealer |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| Validant | , | Renamed Eliquent Life Sciences |
| Soin Neuroscience | , | Seems like one guy |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| Interferon Source | , | Bought by PBL Assay Science |
| , | Acquired by Scantox, Sep 2024 | |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| Antyra | , | Gone |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| |
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| Genmab | Plainsboro, NJ | Biologics |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| ImmBio | , | Shut down Nov 2019 |
| , | No news 2020 - Dec 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| , | Website down Jun 2025 - Dec 2025 | |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| Antabio | Labège, France | Antibacterial drugs |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| AstraZeneca | Boston, MA | Biologics |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| GemacBio | , | Renamed PolyNeuroS |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| Novalar | , | Licensing agreement, essentially gone |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| , | No news 2021 - Sep 2025 | |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Kalypsys | , | Gone |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| IR2Dx | , | Gone, 2019 |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| AdvaStim | , | Shut down, Dec 2017 |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Nuvation Bio | New York, NY | Oncology Treatments |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| , | Stopped work Aug 2025, IP company | |
| Micropore Technologies | Hyderabad, India | Membrane-Based Process Equipment |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Okairos | , | Acquired by GSK, May 2013 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Biotia | Brooklyn, NY | AI Genomics |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| DDi | Basel, Switzerland | Clinical Software |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| , | Shut down Jan 2025 | |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| BA Sciences | Salem, NH | Analytical Services |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| ECI Biotech | , | Gone 2016 |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| , | Renamed Turing Medical | |
| Vernay | Griffin, GA | Fluid Control Solutions |
| rhealth | Bedford, MA | Diagnostics |
| Genetron Health | Beijing, China | Diagnostics |
| DiAthegen | , | Website Gone Oct 2015 |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| MindWalk | Victoria, BC | Custom Antibodies |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Ectycell | , | Part of Cellectis |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| ImmunArray | , | Shut Down, 2021 |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Bioasis Technologies | , | Closing down Jun 2023 |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Acumed | Hillsboro, OR | Medical Implants |
| In Cell Art | , | Website taken over Feb 2025 |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| Algenics | , | Website gone Dec 2015 |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| Alibion | , | Website down May 2021 - Sep 2021 |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| , | Website down May 2025 - Dec 2025 | |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| , | Website taken over, Feb 2026 | |
| TargeGen | , | Bought by Sanofi 2010 |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| , | Dissolved Jun 2019 | |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Manhattan Pharmaceuticals | , | Gone |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Stryker | Salt Lake City, UT | Medical Devices |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Odyssey Thera | , | Shut down 2014 |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| ViraCyte | , | Renamed AlloVir |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| X7 Research | , | Website hijacked Feb 2025 |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| , | Shut down Oct 2024 | |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| CombinatoRx | , | Now Zalicus |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| Pfizer | Ringaskiddy, Ireland | API production |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| , | Website down May 2025 - Dec 2025 | |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| , | Acquired by HB Fuller, Jul 2023 | |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| Essential Pharma | Egham, UK | Generics |
| MDQuest | , | Website Down Feb 2025 |
| GenEndeavor | Hayward, CA | Diagnostics |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| IDM Pharma | , | Acquired by Takeda |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| Raze Therapeutics | , | Closed due to complicated biology |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Lumen Bioscience | Seattle, WA | Biologics |
| InnoCare | Beijing, China | Cancer Treatments |
| NIOX | Morrisville, NC | Asthma management device |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| RepRegen | , | Gone, 2014 |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Kasocio | , | Liquidated, Dec 2019 |
| , | Renamed Aspen Neuroscience | |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| , | Acquired by Arterex, Jun 2023 | |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| Sixal | , | SBIR, Presumed defunct |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| Summation Bio | , | Shut down May 2023 |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| Sanovel | Istanbul, Turkey | Generics |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| XtalPi | Beijing, China | AI Drug Design |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| GenoImmune | , | |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| , | Website down Jul 2025 - Dec 2025 | |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Novaliq | Cambridge, MA | Drug Delivery |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Geron | Foster City, CA | Small Molecule |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| Purely Proteins | , | All employees gone, no info |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| ROKIT | Seoul, Korea | Organ Regeneration |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| Avema Pharma | , | Bought by PL Developments |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| , | Website down Jan 2026 - May 2026 | |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| , | Acquired by MMS, Feb 2025 | |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Chanelle Pharma | Amman, Jordan | Generics |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Lusochimica | , | Owned by Menarini |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| Groove Biopharma | , | Gone 2015 |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Glide Pharma | , | Renamed Glide Technologies |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| AMDL | , | Now Radient Pharmaceuticals |
| RSSL | Wokingham, UK | Analytical Services |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Weatherden | London, UK | Clinical Consulting |
| TissUse | Berlin, Germany | Multi Organ chip |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Nephros | South Orange, NJ | Dialysis Devices |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Lipid Genomics | , | Seems unserious |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Biotox Sciences | , | Renamed BTS Research |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| Neurologix | , | Bankrupt, Liquidation |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| , | Acquired by Lonza, Apr 2017 | |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| Therorna | Beijing, China | RNA Therapies |
| Ionpath | , | Shut down Feb 2025 |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Novartis | Emeryville, CA | Diagnostics |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| NIOX | Uppsala, Sweden | Asthma management device |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Hybrigenics | , | Renamed ATON |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| , | ||
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| Kegelbell | , | Shut down, Dec 2024 |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Pangenetics | , | Bought by Abbott |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| , | Website down Nov 2025 - Apr 2026 | |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| Gene Signal | , | Bankrupt, Apr 2021 |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Genetic Technologies Group | , | Renamed geneType |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| , | No news Aug 2019 - Jan 2026 | |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Instil Bio | Dallas, TX | Cell Therapy |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Smart Biosciences | , | Renamed sb-Peptide |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Baxter | Deerfield, IL | Medication Delivery |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Padagis | Allegan, MI | Generics |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| , | Website down Sep 2025 - Dec 2025 | |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| M3 Wake Research | Encino, CA | Clinical Research |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Biotel | , | Acquired by CardioNet, 2010 |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| Calibrant | , | Closed |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Nucryst | , | Bought by Smith & Nephew |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| Lyman Biopharma Consulting | , | Switched to writing |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| , | Acquired by Healx, Sep 2025 | |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Boston Neurosciences | , | Website down Jun 2020 |
| NewHeart Devices | , | Gone |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| TamuroBio | , | Shut Down Jun 2024 |
| , | Website down Jan 2026 - May 2026 | |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| , | Website down Dec 2025 - Jun 2026 | |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| NeuroVista | , | Website Gone, President has new job |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| , | Website down Dec 2025 - Apr 2026 | |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Starkey | Eden Prairie, MN | Hearing Aids |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Abviva | , | Gone, 2008 |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Intica Biomedical | , | Bankrupt 2014 |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| , | Shut down Oct 2025 | |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Medicomp | , | Renamed ReactDx |
| Techne | , | Part of R&D Systems |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| Strides Arcolab | , | Now just Strides |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| , | Now PiSA USA | |
| Saffron Therapeutics | , | Website down Oct 2021 |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Biotechnical Services | , | Shut down Apr 2019 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| TearScience | , | Acquired by J&J, Nov 2017 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| , | Founder, Principal gone Sep 2024 | |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| Curadev | Noida, India | Immuno-oncology |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| ExcelseBio | , | Part of IntegrityBio |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Omnitura | , | Website gone Jan 2022 |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| , | Website down Nov 2025 - Apr 2026 | |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| , | Website down May 2025 - Dec 2025 | |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| VGX Pharmaceuticals | , | Merged with Inovio |
| Bayer | Berlin, Germany | Small Molecules |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| PharmedArtis | , | Gone 2019 |
| , | 16 years in, CMO is CEO elsewhere Dec 2025; fka Glycoregimmune | |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| Carolus Therapeutics | , | Business revoked in CA |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Hologic | Beijing, China | Diagnostic, Imaging |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| , | Website down Sep 2025 - Dec 2025 | |
| , | Seems gone, Feb 2026 | |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Hepalink | Shenzhen, China | Heparin API |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Formycon | Martinsried, Germany | Biosimilars |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Formurex | Stockton, CA | Contract Research |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| mAbRx | , | Gone |
| SaluMedica | , | Website Gone Jul 2015 |
| vTv Therapeutics | High Point, NC | Small molecules |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| CGT Global | Folsom, CA | Tissue Sourcing |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| Elegen | San Carlos, CA | DNA writing |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Bluestar Genomics | , | Renamed ClearNote Health |
| Remora Therapeutics | , | Shut down 2021 |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Panaxia | Lod, Israel | Medical Cannabis |
| Kinaxo | , | Bought by Evotec |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Pharmaron | Ningbo, China | R&D Services |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| RegeneraTEch | , | Renamed Regencor |
| , | Bankrupt, ceased operations Mar 2026 | |
| Santen | Osaka, Japan | Ophthalmics |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| ARCBio | , | Shut down 2014 |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Intellirod Spine | , | Sold Assets late 2020 |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Vericel | Ann Arbor, MI | Cellular Products |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| TheraLogics | , | Been around since 2008, but no site or current info |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| Iproteos | , | Products now with Accure Therapeutics |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Altasciences | Auxvasse, MO | Contract Research |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| SutroVax | , | Renamed VaxCyte |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Integer | Chaska, MN | Medical & Surgical Devices |
| , | Renamed PsiThera, Dec 2025 | |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| DxTech | , | Seems gone. No info Dec 2015 |
| Launchpad Therapeutics | , | |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| , | Shut down May 2026, assets to Innoviva | |
| Surface Logix | , | Bought by Nano Terra |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| , | Website down Jan 2026 - Mar 2026 | |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| Serentrix | , | Seems gone Apr 2022 |
| Stiefel | , | Acquired by GSK |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Qlucore | Lund, Sweden | Visualization Software |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| , | Website down Nov 2025 - Dec 2025 | |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Core Prognostex | , | Seems inactive |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| FineHeart | Pessac, France | Heart Failure Device |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| , | Acquired by Crypto Group, Jan 2025 | |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| NantCell | , | Renamed ImmunityBio |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| GenomeKey | Bristol, UK | IVD Device |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Medtronic | Galway, Ireland | Medical Devices |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| QSV Biologics | , | Website Gone |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| Instapath | Houston , TX | Automated Digital Pathology |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Beta-Pro | , | Now Triangle Research Labs |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Keenova | Hazelwood, MO | Small Molecules |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Western Biologics | , | Dissolved, 1998 |
| Baxter | Singapore, Singapore | Medication Delivery |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Acelyrin | , | Merged into Alumis, May 2025 |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| Texcell | Shanghai, China | Contract Research |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Regulaxis | , | No news 2020-2024 |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| , | No news Sep 2010 - Oct 2025 | |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| Axbio | Santa Clara, CA | Biochips |
| Ximedica | Providence, RI | Medical Device Services |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Caidya | Raleigh, NC | Clinical Research Organization |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| Deinove | , | Bankrupt Mar 2023 |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Vodori | Chicago, IL | Commercial Content Software |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| Xencor | Pasadena, CA | Antibody Discovery |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| XellSmart | Shanghai, China | Cell Therapy |
| Optherion | , | Sold Assets, Still Exists |
| LyoGo | , | Website gone, all employees gone |
| Bioventus | Durham, NC | Orthobiologics |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| BenuBiopharma | , | Shut down Sep 2023 |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| OncoCell MDx | , | Renamed Immunis.AI |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| Veravas | Oakdale, MN | Diagnostics |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| Novartis Animal Health | , | Acquired by Lilly |
| , | Acquired by MasterControl, Mar 2025 | |
| Altasciences | Scott Township, PA | Contract Research |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Epiomed Therapeutics | , | Gone |
| ABgene | , | Bought by Apogent, Dec 2001 |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| Vrata Therapeutics | Cambridge, | |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| Stago | Franconville, France | Diagnostics |
| Lavipharm | East Windsor, NJ | Small molecules |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| neoSurgical | , | Shut down 2017 |
| , | Acquired by Stryker, Oct 2024 | |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Pion | Billerica, MA | Dissolution Data |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| BioMap | Palo Alto, CA | AI Models |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cunde Medical | , | mRNA Cell Therapy combo |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| Mustang Bio | Worcester, MA | Immunotherapies |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Ergomed | London, UK | Clinical Research |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| Pulse Biomedical | , | Distributor |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| TcLand Expression | , | Website Gone |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Partek | , | Acquired by Illumina, May 2024 |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Savant HWP | , | Gone 2019 |
| Geneffects | , | Shut down Feb 2020 |
| Molecular Throughput | , | Rebranded as mtibio |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Helsinn | Dublin, Ireland | Small Molecules |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| Staburo | Munich, Germany | Clinical Services |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| PathoGene | , | Website taken over, Oct 2017 |
| TrialStat Solutions | Montreal, QC | eClinical |
| , | Website down Jan 2026 - Apr 2026 | |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| GeneDx | Stamford, CT | Genetic Data |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| Elix | Tokyo, Japan | AI Drug Discovery |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Lux Biosciences | , | Gone |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Kate Therapeutics | , | |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| Kendle | , | Acquired by INC Research 2011 |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| BioTheryX | San Diego, CA | Small Molecules |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Qool Therapeutics | , | Gone Jan 2021 |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Organon (2) | Jersey City, NJ | Women's Health |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| CultureTrax | , | Shut Down Dec 2019 |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Penwest | , | Bought by Endo |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| DxNow | , | Renamed ZyMot fertility |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Trident Lifeline | Surat, India | Generics |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| ArgusEye | Linköping, Sweden | Biosensors |
| Steba Biotech | , | Renamed ImPact Biotech |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Action Pharma | , | Abbott acquired product, 2012 |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Rezo Therapeutics | San Francisco, CA | |
| Advena | Bromsgrove, UK | Medical Device Regulatory Consulting |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Derma-Cell Research | , | Website gone Nov 2019 |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Androclus Therapeutics | , | Closed, May 2007 |
| Synthon | , | |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Biomendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| iCeutica | , | Seems gone, Jan 2022 |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| LemnaGene | , | Acquired by Biolex 2005 |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| Aerogen | Galway, Ireland | Nebulizers |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| , | Website down Aug 2025 - Jan 2026 | |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Neurogene | New York, NY | Genetic Therapies |
| SpinalMotion | , | Website gone, 11-30-14 |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| ICN Pharmaceuticals | , | Now Valeant |
| , | Website down Jan 2026 - May 2026 | |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| , | Now part of Sanisure, Jun 2026 | |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Promethera Biosciences | , | Renamed Callaion |
| OptiVia Medical | , | Website looks pretty terrible |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| NanoTess | Calgary, AB | Biocatalysts |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| , | Website down Aug 2025 - Jan 2026 | |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| , | Renamed Novakand Pharma, Sep 2025 | |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| Molsoft | San Diego, CA | Drug Design Software |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| ImmuVen | , | Website gone, Dec 2015 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Pharminox | , | Website gone, Aug 2017 |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Avexa | , | Renamed Novita Healthcare |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| Proteotech | , | Website gone Jul 2015 |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| Cardeas Pharma | , | Gone, 2017 |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| , | No news 2021 - Jan 2026 | |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| , | Seems to have shut down mid 2025 | |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| Large Scale Biology | , | Shut Down |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Quartet Medicine | , | Wound down, Nov 2017 |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Aixlie Pharmaceuticals | , | No idea what happened |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Averion | , | Now Aptiv |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| , | Renamed Trace Biosciences | |
| ErVimmune | Lyon, France | Cancer Vaccines |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Purdue Pharma | Stamford, CT | Small Molecules |
| BGI | Shenzhen, China | Genetic Testing |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| Altan Pharma | , | Acquired by Ethypharm |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Nascent Biologics | , | Changed to Nascent Biotech |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| YMC Process Technologies | Devens, MA | Purification Technology |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Apic Bio | , | Shut down Jan 2024 |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| APT Therapeutics | , | Shut down Mar 2019 |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Apini Therapeutics | , | |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| WntResearch | , | Shell acquired by Opsy |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| GlycoEra | Boston, MA | Custom Glycan Platform |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Genocea Biosciences | , | Winding Down May 2022 |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Tisucor | , | Shut down Feb 2020 |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| Gentegra | , | Part of IntegenX |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Coley Pharma | , | Acquired by Pfizer |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Integer | Plano, TX | Medical & Surgical Devices |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Z-Factor | , | Centessa Company |
| , | Website down Jul 2025 - Nov 2025 | |
| RK Pharma | Pearl River, NJ | Generics |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| NeuralInk | Fremont, CA | Neural Implants |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| SemBioSys | , | Bankrupt, Jul 2012 |
| MLAB Biosciences | Needham, MA | Biologics |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Pharmexa | , | Merged into Affitech, May 2009 |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| BioClinical Solutions | Chicago, IL | Clinical Trial Solutions |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| PTM BioLabs | , | Renamed PTM BIO |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| , | Website down Nov 2025 - Apr 2026 | |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| Piramal | Grangemouth, UK | CDMO |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| nitec Pharma | , | Merged with Horizon Pharma |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| Amakem | , | Website gone Dec 2015 |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Synlab | Munich, Germany | Clinical Lab Services |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Stealth Therapeutics | , | Gone |
| Quantificare | Maringa, Brazil | Medical Imaging |
| GeneoDx | , | Website gone Oct 2019 |
| CP Life Science | , | Split and became Medvacon |
| Apollo Scientific | Manchester, UK | Research Products |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| Alms Therapeutics | , | Gone Jul 2022 |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| PMG Research | , | Now Acellacare |
| CATO SMS | , | Renamed Allucent, May 2022 |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| Pharmaron | Xi'an, China | R&D Services |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Orion Genomics | St. Louis, MO | Biomarkers |
| Trilations | New York, NY | Strategic Consulting |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Celsis | , | Now AAIPharma |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| Minakem | Dunkerque , France | API Manufacturing |
| Nostrum Laboratories | Kansas City, MO | Generics |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| algorithmRx | , | Now Venebio |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| EmpathBio | , | |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Regenica Biosciences | , | Gone Nov 2020 |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| BioPointe Scientific | , | Subsumed into parent |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| Cellf BIO | , | Website taken over Jan 2019 |
| Avecris | Singapore, Singapore | Gene Delivery |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| TRIA Bioscience | , | Shut down Aug 2021 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| Precise Bio | , | Gone 2023 |
| Medtronic | Shoreview, MN | Medical Devices |
| Michigan Clinical Research Institute | , | |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| Insamo | , | |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| MabPrex | , | Out of business, 2016 |
| , | Website down Oct 2025 - Jan 2026 | |
| New Brunswick Scientific | , | Merged into Eppendorf |
| , | Website down Jan 2026 - May 2026 | |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Optimata | , | Shut down May 2019 |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| DiaGenic | , | Switched to energy sector |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Allometra | , | Gone |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| ConquerX | , | Dissolved Jun 2021 |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| Prescos | , | Shut down Feb 2014 |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| A2IDEA | , | Only employee left Jan 2024 |
| Arraystar | Rockville, MD | Microarrays |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Koelis | Meylan, France | Prostate Biopsy System |
| Proteins and Peptide Management | , | Now Adocia |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| HackScience | , | Renamed Cytera, Nov 2018 |
| MOgene | St. Louis, MO | Genomic Services |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Atugen | , | Acquired by SR Pharma 2005 |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| Nanobiotix | Paris, France | Nanoparticles |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| Synergen | , | Bought by Amgen 1994 |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| , | Website down Sep 2025 - Feb 2026 | |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| CSL Behring | Bradley, IL | Biologics |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| Palingen | , | Renamed IGM Biosciences |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Genyro | San Francisco, CA | DNA Construction Technology |
| Inexia | , | Acquired by Centessa |
| Sharp | Conshohocken, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| SWITCH Biotech | , | Gone, 2020 |
| Digene | , | Merged with Qiagen |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| Prochon Biotech | , | Acquired by Histogenics |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| CTIBIOTECH | Philadelphia, PA | Tissue Sample |
| MaxThera | , | Shut Down Dec 2011 |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| AB ANALITICA | Padua, Italy | Sequencing products |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| Figure8 Surgical | , | Surrendered business in CA |
| SteriTech | Surrey, UK | Process Equipment |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Davol | , | Acquired by Bard, 1980 |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| CSL Behring | King of Prussia, PA | Biologics |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| , | Website down Aug 2025 - Jan 2026 | |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| ExThera Medical | Martinez, CA | Blood filtration |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| Carrington Labs | , | Changed Name to DelSite |
| Lavipharm | Paris, France | Small molecules |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| , | Website down May 2025 - Jan 2026 | |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| , | Acquired by hVIVO, Jan 2025 | |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| CereScan Corp | , | Renamed CereHealth |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Neurotronik | , | Most employees moved to InnerPulse |
| Gentel Bio | , | Ceased Operations 2012 |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| CyBio | , | Merged into Jena, Jul 2014 |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Cala Health | San Mateo, CA | Neurological Device |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Mardil Medical | , | Website gone Feb 2021 |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| Nido Surgical | , | Shut down Apr 2022 |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Abcam | Cambridge, UK | Antibodies |
| Endocare | , | Website down Jan 2021 - May 2021 |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| , | Website down Jan 2026 - May 2026 | |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| , | Acquired by Merit Medical, Jun 2023 | |
| Microsize | Quakertown, PA | Microionization CDMO |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| LinkChem | Shanghai, China | CDMO |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| Argolight | Pessac, France | Microscopes |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| MatTek | Ashland, MA | Cell Products, Services |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Advansta | San Jose, CA | Protein characterization products |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Biogenes | Berlin, Germany | Antibodies |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| , | No news 2020 - Apr 2026 | |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Cellex | , | Presumed Gone |
| Iontas | , | |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Java Clinical | , | Website gone Jun 2019 |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Getinge | Rastatt, Germany | Medical Technology |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Howfond | , | Website gone, Jul 2015 |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| Dharma Biomedical | , | Website gone Nov 2022 |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| Celest Therapeutics | , | |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| SereDigm | , | Gone Nov 2009 |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| FemtoVox | , | |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| TRIFARMA | Chennai, India | APIs |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Transmed Oncology | , | Gone? |
| Pharmion | , | Acquired by Celgene 2007 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Flow Eighteen38 | , | |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| , | Website down Aug 2025 - Jan 2026 | |
| Meissner | Castlebar, Ireland | Lab Systems |
| Alcon | Zug, Switzerland | Eye-Care Products |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Ambion | , | Bought by Applied Biosystems 2006 |
| Nodality | , | Gone |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| D-Pharm | , | Website Gone, Aug 2016 |
| Allux Medical | , | Shut down, Feb 2009 |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Lacer | Barcelona, Spain | Small Molecules |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Aresus Pharma | , | Seems folded in to Dermago |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| LivaNova | London, UK | Nerve stimulation therapy |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| VitamFero | , | Website gone Aug 2018 |
| Proteom | , | Acquired by Amura Ltd |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Alizyme | , | Bankrupt 2009 |
| Sierra Neuropharmaceuticals | , | Not active |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| Meabco | , | |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Élancé Therapeutics | , | Bispecific Antibodies |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Intellikine | , | Bought by Millennium 2011 |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| , | Acquired by Altaris, Mar 2025 | |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| Hemanext | Avon, MA | Transfusion Technologies |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Resprotect | , | No update since 2012 as of 2020 |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| Nereus | , | Website Gone late 2013, no info |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Medipacs | , | Shut down Jul 2024 |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| , | Website down Aug 2025 - Jan 2026 | |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| Stago | Clarkston, GA | Diagnostics |
| Tasso | Seattle, WA | Blood-collection products |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| Graybug | , | Now Graybug Vision |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Diversa | , | Merged with Celunol to become Verenium |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Precision Virologics | , | Precision Virologics |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Nina Biotherapeutics | , | Gone, after 2015 |
| CisThera | , | Shut down Jan 2023 |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| AC Diagnostics | , | Website from 2004 |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| CanTx | , | Website gone, Feb 2015 |
| , | Acquired by ETAP Group, Oct 2023 | |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Almac | Craigavon, UK | Pharmaceutical Services |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| , | Website down Dec 2025 - Feb 2026 | |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Novotech | Auckland , New Zealand | Clinical Research |
| , | Website down May 2025 - Sep 2025 | |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| MedShape | , | Acquired by DJO, Apr 2021 |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| , | Liquidation, Jun 2025 | |
| Immune Technology Corp | New York, NY | Virology research products |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Orros Therapeutics | , | gone 2018 |
| TaiwanBio | , | Website gone Oct 2021 |
| InBios International | Seattle, WA | Clinical Diagnostics |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| JCL Bioassay | , | Renamed CMIC |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| Cellink | Kyoto, Japan | Bioprinting |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| Niche Generics | Hitchin, UK | Contract Generics |
| Verséa Health | Tampa, FL | Diagnostics |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| Sharp | Macungie, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Corcym | London, UK | Implants, Instruments |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Zumutor Biologics | Bangalore, India | Biologics |
| Repligen | Waltham, MA | Protein Manufacturing |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| , | Website down Dec 2025 - Apr 2026 | |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| CardioEphEx | , | Shut down Dec 2020 |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| StromaCyte | , | Small time, no info. Defunct |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Piramal | Hyderabad, India | CDMO |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| Cuda Pharmaceuticals | , | Presumed gone |
| YishengBio | , | Now YS Biopharma |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Oncorus | , | Liquidated, Jun 2023 |
| , | Shut down Jul 2025 | |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Cellcion | , | Website gone, company going inactive |
| BGI | Copenhagen, Denmark | Diagnostics |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| Rheos Medicines | , | Shut down Dec 2022 |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| GliaGen | , | Renamed CaCy Therapeutics |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Cardima | , | Bankrupt Dec 2010 |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Acologix | , | Closed Aug 2011 |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Celula | , | Acquired by NeoSeq |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| Stago | Asnières sur Seine, France | Diagnostics |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| GnuBIO | , | Bought by Bio-rad |
| Venebio | Glen Allen, VA | Consultants |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| ResearchDx | Irvine, CA | Diagnostics |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| , | Acquired by Kite, Aug 2025 | |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| NeurAegis | , | Seems gone, Sep 2022 |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| X2 Pharma | , | Website Gone |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Glysantis | , | Shut down Late 2020 |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Osteolab | , | Spam site |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| AngioCure | , | Employees all gone, Nov 2017 |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| , | Website down Aug 2025 - Dec 2025 | |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Piramal | Ahmedabad, India | CDMO |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Kembiotix | , | No info, Aug 2022 |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| Hesperos | Orlando, FL | Human-on-a-chip |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| MilliporeSigma | Madison, WI | Small Molecules |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| , | Website down Jan 2026 - May 2026 | |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| Mabimmune | , | Merged with Neurimmune |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| CFL Biotech | , | Website gone Jul 2020 |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| Automata | London, UK | Lab workflow automation platform |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| OccuRx | , | Merged into Certa Therapeutics |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Life Stem Genetics | , | Basically gone |
| Syneos Health | Princeton, NJ | Clinical Development |
| Stada | Bad Vilbel, Germany | Generics |
| NewVac | , | |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| , | Acquired by Novanta, Jun 2026 | |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Audubon Bioscience | Houston, TX | Biospecimens |
| Curexsys | , | Dissolving, Jul 2024 |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| GNA Biosolutions | , | Now part of HP Health |
| TranS1 | , | Renamed Baxano Surgical |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| Proteome Sciences | Surrey, UK | Proteomics |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| , | Gone before Dec 2025 | |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Evolve BioSystems | , | Renamed Infinant Health |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Mytos | London, UK | Automated Cell Culture |
| , | Website hijacked Oct 2025 | |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| , | Website down Jun 2025 - Dec 2025 | |
| Cell Targeting Inc | , | Bought by Biotime |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| MeDiNova Research | , | Now part of Accelacare |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| IDRx | , | Acquired by GSK, Feb 2025 |
| Evocutis | , | Pivoted to investments |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| , | Website taken over Feb 2026 | |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| HebeCell | Natick, MA | Cell Therapies |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| TRIFARMA | Rozzano, Italy | APIs |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| Activ Surgical | Boston, MA | Surgical Software |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Castor | Claymont, DE | eClinical Trial Software |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Syncro Medical | Langhorne, PA | Software development |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| AbBaltis | Kent, UK | Plasmas & Sera |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Norgine | Uxbridge, UK | Specialty Pharma |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Encorium | , | Bankrupt |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| IQVIA | Durham, NC | Clinical Research |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| LifeSensors | , | Website hijacked Feb 2025 |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Obexia | , | Gone |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| BiOM | , | Now BionX Medical |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Optime Therapeutics | , | Acquired by Lippomix |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| , | No news 2019 - Sep 2025 | |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Genmab | Utrecht, Netherlands | Biologics |
| NeurAxon | , | No updates since 2008 |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Aztech Sciences | , | Website gone Jun 2021 |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Endovasc | , | Bankrupt 2008 |
| Transave | , | Merged with Insmed Dec 2010 |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| MetaMol Theranostics | , | Gone |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| Omnimmune | , | Shell company, trademark abandoned |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| Peptimmune | , | Liquidated 2011 |
| Affigen | , | Liquidating Fall 2019 |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Affinity Bio | , | Renamed MyriO Tx |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| CellASIC | , | Bought by Millipore, May 2012 |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Novasecta | London, UK | Pharma Consultancy |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| , | Website down Sep 2025 - Dec 2025 | |
| Symansis | Timaru, New Zealand | Reagents |
| , | Website down Oct 2025 - Jan 2026 | |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| Translational Bioscience | , | |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| SNBL | , | Acquired by Altasciences |
| |
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Beardsworth | , | Bought by TFS International 2013 |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Empatica | Cambridge, MA | Seizure Detection |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| Zylacta | , | No news 2015 - Oct 2024 |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Life Analytics Group | , | Gone |
| Viwit | Shanghai, China | APIs, Formulation |
| Incyte | Wilmington, DE | Small Molecules |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Korio | Doylestown, PA | RTSM Platform |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| Biocode Hycel | , | Website gone |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| MediWound | Yavne, Israel | Wound & Burn Care |
| , | No news 2019 - Sep 2025 | |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| , | Website taken over Feb 2026 | |
| Grunenthal | Origgio, Italy | Small molecules |
| , | Website down Jun 2025 - Dec 2025 | |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Elektrofi | Boston, MA | Biologics Formulation |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| Zyomyx | , | Closed as of 2014 |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| Proteorex | , | Gone Nov 2017 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| , | Website down Oct 2025 - Feb 2026 | |
| Glenveigh Medical | , | Website down Sep 2024 |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| BaseCure Therapeutics | , | |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| , | Filings late Mar 2025 - Feb 2026 | |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| Marical | , | Website Gone |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Genitope | , | Wound Down |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| , | Acquired by Galecto, Nov 2025 | |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| Peptone | London, UK | Translational Biophysics |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| 10BioSystems | , | Website Gone, Apr 2016 |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Nucleus Network | Herston, Australia | Clinical Research |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| , | Renamed ElisiGen, Dec 2025 | |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Grid Biosciences | New Territories, China | Vaccines |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Axxam | Milan, Italy | Drug discovery services |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| Dalex Biotech | , | Gone |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| Maplehurst Genetics International | , | Website gone |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Genuiti Therapeutics | , | |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Myrexis | , | Liquidating 2013 |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Ovation.io | Portland, ME | LIMS |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Anchen | , | Bought by Par Pharmaceutical |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| Maxwell Biosciences | Austin, TX | Antivirals |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Dendritix | , | Renamed Argos Therapeutics |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| MantraPharma | Lévis, QC | Generics |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Noscira | , | Liquidated |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| LifeQual Pharmaceuticals | , | Website Gone |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| seqWell | Beverly, MA | Sequencing Service |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| , | Website down Sep 2025 - Dec 2025 | |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Satya | Hyderabad, India | Small Molecule |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Novita Healthcare | , | Renamed TALi Digital |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Effipharma | , | Marked as closed by Google |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| Bayer | Bergkamen, Germany | Small Molecules |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| CovalX | Woburn, MA | Protein Complex Analysis |
| , | Website down Jan 2026 - May 2026 | |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Fabric Genomics | Oakland, CA | Computational genomics |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Lavipharm | Peania, Greece | Small molecules |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| ATON | Shanghai, China | CDMO |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| , | Renamed Valion Bio, Apr 2026 | |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| On-Q-Ity | , | Closed 2013 |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Statera Therapeutics | , | Shut down Jan 2022 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| XDx | , | Changed name to CareDx |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| Vernacare | Blackwood, UK | Surgical Devices |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| Mirador Biomedical | , | Shut Down 2019 |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Iktos | Paris, France | AI for New Drug Design |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Creative Bioinformatics Consultants | , | Gone |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| , | Website down Jan 2026 - May 2026 | |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Innexus Biotechnology | , | Gone |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| PreventAGE Health Care | , | fka Journey Biosciences |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| August Bioservices | Nashville, TN | Research & Development Services |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Avalyn Pharmaceuticals | Cambridge, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Recopharma | , | Seems gone |
| , | Website down Sep 2025 - Feb 2026 | |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| Tgen Tech | , | Renamed Annoviant |
| , | Website gone Feb 2026 - Jun 2026 | |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| , | Acquired by IQVIA | |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| Olio Labs | San francisco, CA | Software to de-risk clinical trials |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| Qurasense | , | Renamed Qvin |
| AlphaMab Oncology | Suzhou, China | Biologics |
| Körber | Hamburg, Germany | Production Monitoring Software |
| RheoSense | San Ramon, CA | Viscometers |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| XenaCare | , | Gone |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Curry Pharmaceuticals | , | Closed 2008 |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| Norganoid | Macclesfield, UK | Organoid Technology |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| SoBran | Falls Church, VA | Preclinical Services |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Apotex | Toronto, ON | Small Molecule Generics |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| AmplifyBio | , | Shut down Apr 2025 |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| , | Shut down Oct 2024 | |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Proxima | New York, NY | AI Protein Folding Platform |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Ionian Technologies | , | Gone Mar 2016 |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| , | Website down Aug 2025 - Jan 2026 | |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| InnoVoyce | Boston, MA | ENT Lasers |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Ileo Science | , | Seems gone Mar 2022 |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Clinnex | Ahmedabad, India | Clinical Research |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Xenova | , | Acquired by Celtic Pharma |
| Cellevolve Bio | , | Shut down Aug 2023 |
| , | Acquired by Fujirebio, 2022 | |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Sinotherapeutics | Shanghai, China | Generics |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| Evestra | San Antonio, TX | Women's Health |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| MSD | Dublin, Ireland | Women's Health Products |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| Pear Bio | London, UK | Cancer Treatment Selection |
| EndoStim | , | Shut down Jan 2020 |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| ProtonDx | London, UK | Diagnostics |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Attogene | Austin, TX | Rapid Diagnostics |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| TheraCoat | , | Renamed UroGen Pharma |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Ekteino | , | Closed, Dec 2016 |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| , | Pivoted to Crypto, Oct 2025 | |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| Meristem Therapeutics | , | Defunct |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Riboxx | Dresden, Germany | RNA Products |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| Gameto | New York, NY | Female Fertility Extension |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| Abbott | Clonmel, Ireland | Stents |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| AL-S Pharma AG | , | New Dec 2016, no site Aug 2018 |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Univfy | Los Altos, CA | IVF reports |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| , | Acquired by IQVIA | |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| GenSensor | Nantes, France | Process Analytical Technology |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| Mesoblast | New York , NY | Regenerative Medicine |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| West-Ward | , | Now part of Hikma |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| ISM Therapeutics | , | Website Gone, no response from employees |
| EuroAPI | Paris, France | API Production, CDMO |
| Iquum | , | Acquired by Roche, Apr 2014 |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Getinge | Hechingen, Germany | Medical Technology |
| CMD Bioscience | , | Closed, 2015 |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Sunol Molecular | , | Assets sold 2005 |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Vivamer | , | Shut down, Jul 2015 |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Synentec | Elmshorn, Germany | Cell Imaging |
| 3T Biosciences | South SF, CA | TCR Therapies |
| Pharmaron | Louisville, KY | R&D Services |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| , | Website down Jun 2025 - Dec 2025 | |
| Target Medicals | , | No news 2016 - Oct 2024 |
| Qardio | Covina, CA | Portable Heart Monitors |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| NovoKera | , | Merged into Longevity Biomedical |
| Pharsight | , | Merged with Tripos to become Certara |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| , | Redirecting to Siemens, Feb 2026 | |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| Ergomed | Geneva, Switzerland | Clinical Research |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| GenSure | Shijiazhuang, China | Diagnostics |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Mednoxa | , | Website gone Jan 2020 |
| STX-Med | , | Renamed Cefaly |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| , | Website down Jan 2026 - Mar 2026 | |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| BiVACOR | Houston, TX | Heart replacement |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| , | Website taken over May 2026 | |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| , | Renamed Stelexis BioSciences | |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| Heragen | , | Gone |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Boston Scientific | Spencer, IN | Medical Devices |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Sonosine | Kidlington, UK | Medical Imaging |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| CereSpir | , | No news 2020 - Nov 2024 |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| AstraZeneca | Baar, Switzerland | Biologics |
| Synthace | London, UK | Development Software |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Norton Scientific | , | Website Gone, Oct 2014 |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| Ocean Therapeutics | , | Shut down June 2013 |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| OrphoMed | , | Shut Down 2022 |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| Nuredis | , | Shut Down Apr 2021 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| , | Website down Oct 2025 - Feb 2026 | |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Solvanix | , | Shut down Nov 2023 |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| Stago | Tianjin, China | Diagnostics |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Spirox | , | Bought by Stryker, Jul 2017 |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Novotech | Melbourne, Australia | Clinical Research |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| , | Website taken over Feb 2026 | |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| Roche | Burgess Hill, UK | Diagnostics |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| Chanelle Pharma | London, UK | Generics |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| TauTaTis | , | Shut down 2011 |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| Imalux | , | Ceased Operations, Apr 2014 |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| bespark*bio | Vienna, Austria | Consulting |
| , | No news Jan 2021 - Jan 2026 | |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| yuFlu | , | No website, no info Feb 2021 |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Roche | Mississauga, ON | Small Molecules |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| SynAm Vaccine | , | Gone 2017 |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Proteonomix | , | Shell Company |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Seer | Redwood City, CA | Early Detection |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| Seneb Biosciences | , | Gone 2017 |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| AesRx | , | Bought by Baxter, Jul 2014 |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Upstate Biotechnology | , | Closed 2005 |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Appili Therapeutics | Halifax, NS | Small molecule |
| CeQur | Luzern, Switzerland | Insulin pump |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Lorantis | , | Merged with Celldex 2005 |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| Cerimon Pharmaceuticals | , | Gone |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| TransCellular Therapeutics | , | Gone 2019 |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| Strike Bio | , | Assets auction, Aug 2017 |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| GIVAX | Boston, MA | GI Vaccines |
| Synergx | , | Owned by Morphogenesis |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Pharmathen | Marousi, Greece | Generics |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Novocell | , | Renamed Viacyte |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| , | Website down May 2025 - Sep 2025 | |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| OvaGene Oncology | , | Gone Feb 2020 |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Ataia Medical | , | Website taken over Jan 2024 |
| Abazyme | , | Dissolved Jun 2017 |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| , | Part of ICE Pharma | |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Global BioDevelopment | , | Website gone |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| Medrobotics | , | Bankrupt Jun 2022 |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Applied Therapeutics | New York, NY | Small Molecules |
| SGS Quay Pharma | , | |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Angiosyn | , | Acquired by Pfizer 2005 |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| EpiFinder | , | Gone May 2025 |
| Hovione | Mumbai, India | Contract Manufacturing |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| Baxter | Alliston, ON | Medication Delivery |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| Moleac | Singapore, Singapore | Stroke Products |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| Bionsight | Chuncheon, Korea | Database For Research |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Eos Biosciences | , | Shut down Oct 2020 |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| MediQuest Therapeutics | , | Gone? |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| GemoPharm | , | No news 2017-2022 |
| Microphage | , | Bankrupt Jun 2013 |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| , | Website down Jun 2025 - Dec 2025 | |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Sarstedt | Nümbrecht, Germany | Lab products |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| Sanofi | North York, ON | Biologics, Vaccines |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| EmerVax | , | Renamed Circurna |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| , | Renamed Entirety Biomedical | |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Atanse | , | Website gone, May 2018 |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| Genometry | , | Shut down Dec 2019 |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
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| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Sanofi | Haverhill, UK | Small Molecules |
| Kesios Therapeutics | , | Closed down according to investors |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Berg | , | Acquired, Jan 2023 |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Mediatech | , | Now Cellgro |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| Cytosolix | , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| bioRASI | Aventura, FL | Clinical Research |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| GenQual | , | Inactive, Jun 2017 |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Boston Scientific | Valencia, CA | Medical Devices |
| , | Website down Nov 2025 - Apr 2026 | |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Ximedica | San Francisco, CA | Medical Device Services |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| MWG Biotech | , | Owned by Eurofins |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| Neurogene | Houston, TX | Genetic Therapies |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| Pfizer | Puurs, Belgium | Packaging |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Fusion Biopharma | , | Presumed gone |
| Domainex | Essex, UK | Drug Discovery Services |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Curl Bio | , | Shut down Feb 2020 |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| Neopeutics | South SF, CA | Drug discovery contract research |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| LipimetiX Development | , | Website gone, Jan 2020 |
| DesignMedix | , | Shut down Aug 2020 |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Abbott | Longford, Ireland | Diagnostics |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| ApoImmune | , | Gone 2014 |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| Cell Matrix | , | Acquired by Cancervax |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| NEC Oncoimmunity | , | Renamed NEC |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| Regulome | , | Gone 2006 |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| GlioCart | , | |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| Viral Genetics | , | Now VG Life Sciences |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| , | Website down Aug 2025 - Jan 2026 | |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| , | Website taken over Feb 2026 | |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| Hemaquest | , | Gone by 2017, No info |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Cipla | Verna, India | Generics, APIs, Formulation |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Lindus Health | London, UK | CRO |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| Veramed | London, UK | Biostatistics and programming services |
| Droice | New York, NY | AI Clinical Data |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| Orthogonal LLC | Chicago, IL | Medical device software |
| , | Shut down Sep 2025; fka GenoFAB | |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Pfizer | Surrey, UK | Consumer Healthcare |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| Alvea | , | Shut down Oct 2023 |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| Pharos Dx | , | Gone |
| Bayer | Mailand , Italy | Small Molecules |
| Partner Therapeutics | Lexington, MA | Biologics |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Oscor | , | Acquired by Integer, Dec 2021 |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Assurance Scientific Laboratories | Birmingham, AL | Molecular Technologies |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Cambria Biosciences | , | Gone Feb 2008 |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| PharmacoFore | , | Now Signature Therapeutics |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Alcon | Irvine, CA | Eye-Care Products |
| TheoremDx | , | Bankrupt Feb 2020 |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Niveus Medical | , | Closed Dec 2017 |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| , | Pivoted to blockchain, Sep 2025 | |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| Erbe | Tübingen , Germany | Surgical Systems |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| AGI Therapeutics | , | Bought by Videra |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| NormOxys | , | Gone |
| , | Website down Sep 2025 - Dec 2025 | |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Calmune | , | Liquidated |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| CeQur | Greenville, SC | Insulin pump |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| Singular Genomics | San Diego, CA | Genomics |
| Westat | Rockville, MD | Clinical trial design, management, services |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Biomedica | , | Now part of Oxford Biomedica |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| Procognia | , | Website Gone, Layoffs 2014 |
| Quest Clinical Research | , | Now part of eStudysite |
| MacroPore | , | Gone |
| Celerion | Lincoln, NE | Clinical Research |
| Veeva Systems | Shanghai, China | Life Science Software |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Abselion | Cambridge, MA | Biologics Quantification |
| Endomag | Cambridge, UK | Biopsy Tracer |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Lab Owl | , | Part of Inflexion Point |
| , | Acquired by Millipore, Dec 2010 | |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| PPD | Middleton, WI | Contract R & D, Consulting |
| Diassess | , | Renamed Lucira Health |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Adela | Toronto, ON | Liquid Biopsy |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Vascular Biogenics | , | Now VBL Therapeutics |
| , | Website down Sep 2025 - Dec 2025 | |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| Proteintech | Rosemont, IL | Research Antibodies |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| restor3d | Durham, NC | 3D printed implants and devices |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Leucid Bio | London, UK | Cell Therapy |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| Abbott | Singapore, Singapore | Diagnostics |
| Bastion Therapeutics | , | Shut down |
| BHR Pharma | , | Subsidiary of Besins |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| Bacthera | , | Liquidating, Feb 2025 |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Avance Clinical | Firle, Australia | Clinical Research |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| ZyStor | , | Bought by BioMarin, closed |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| , | Website down Oct 2025 - Feb 2026 | |
| Capsigen | Vancouver, WA | AAV Vectors |
| Advanced Genetic Technologies | , | No info |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| , | No news 2017 - Apr 2026 | |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| AtheroGenics | , | Assets Sold Off 2009 |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| CorWave | Clichy, France | Blood Pumps |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| DanPET | , | One guy, Feb 2024 |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Neuro Bio | Oxford, UK | T14 Blocker |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Existence Genetics | , | Bankrupt Dec 2012 |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Ceronco Biosciences | , | Gone 2015? |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| , | Shut down Mar 2026 | |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| Sierra Surgical | , | Shut down Feb 2019 |
| Trine Pharmaceuticals | , | Closed 2008 |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| Alkermes | Wilmington, OH | Small Molecules |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Kereos | , | Seems gone |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| , | Website down Sep 2025 - Dec 2025 | |
| QL Biopharm | Beijing, China | Biologics |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Compliment Corporation | , | Closed Dec 2011 |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| , | Gone Sep 2025 | |
| iBridge Medical | , | Website gone Jan 2020 |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Altiris Therapeutics | , | Presumed Gone |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| PhotoThera | , | Ceased operations Dec 2012 |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| ProUroCare Medical | , | Gone |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| Elixir Medical | Milpitas, CA | Stents |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Veeva Systems | Radnor, PA | Life Science Software |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| BBOT | South SF, CA | RAS-targeted small molecules |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Stat One | Morrisvile, NC | eClinical |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| , | Acquired by Xoma, Sep 2025 | |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Cirina | , | Merged with Grail, May 2017 |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| Calypte Biomedical | , | Gone |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Intelliseq | Kraków, Poland | Genome Informatics |
| V-gene | , | Website gone, Aug 2017 |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| GIPAM | Wismar, Germany | Market Access Consulting |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Akceli | , | Shut down, Sep 2004 |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Bionovica | , | Website gone Dec 2022 |
| , | Merged with ABX-CRO | |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| Catawba Research | Charlotte, NC | Clinical Research |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Roche | Buonas, Switzerland | Diagnostics |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| Cytochroma | , | Acquired by Opko Health |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| EDAP Technomed | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Medelis | Thompson's Station, TN | Clinical Research |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Siga | Corvallis, OR | Small Molecules |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| PolyMedix | , | Bankrupt Apr 2013 |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| genOway | Lyon, France | Rat and cell models |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| CorTechs Labs | , | Renamed Cortechs.ai |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Furong Biotech | , | |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| Xhale | , | Acquired by Philips, Aug 2018 |
| , | Website down Oct 2025 - Jan 2026 | |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Meditrial | New York, NY | Clinical Services, Software |
| HarkerBIO | , | Shut down Apr 2019 |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Jun 2025 - Dec 2025 | |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| DiaVax Biosciences | , | Renamed Helocyte |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Senzime | Uppsala, Sweden | Devices |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| Unilife | , | Bankrupt, Apr 2017 |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| SolaranRx | , | Website taken over |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Talima Therapeutics | , | Closed 2011 |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| BojiMed | Guangzhou, China | Clinical Research |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| NeoCura | Beijing, China | Personalized Vaccines |
| Smithers | Akron, OH | Contract Research |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| Pharma Medica | Toronto, ON | Clinical Services |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| , | Website down Jun 2025 - Dec 2025 | |
| Chrono Therapeutics | , | Shut Down 2019 |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| , | Website down Jul 2025 - Jan 2026 | |
| InteKrin | , | Owned by Coherus Biosciences |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| Norgine | Milan, Italy | Specialty Pharma |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| , | Renamed NeuraNova, Jan 2026 | |
| Silenseed | , | Renamed Silexion |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Inspirata | Tampa, FL | Cancer Insights |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Parcell Labs | , | Website Gone, Oct 2016 |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Arthus Biosystems | , | Shut down Oct 2015 |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| , | Acquired by Sebia, Dec 2022 | |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| , | Website down, Dec 2025 - Jun 2026 | |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Devsynthesis | Austin, TX | Chemistry CRO |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Tolmar | Fort Collins, CO | Small Molecules |
| Salgomed | , | Shut down Apr 2022 |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| , | Pivoted to crypto, Apr 2026 | |
| Zivena | , | Gone |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| , | Shut down Aug 2025 | |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Stryker | Portage, MI | Medical Devices |
| , | Renamed Algernon Health, Oct 2025 | |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Limerick Bio | , | Gone 2011 |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| , | Shut down Mar 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| PACT Pharma | , | Shut down Sep 2023 |
| Verana Health | San Francisco, CA | Clinical Database |
| Parexel | Newton, MA | Clinical Research |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| Metabasis | , | Bought by Ligand |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| DDL | Eden Prairie, MN | Device Testing |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| Piramal | Lexington, KY | CDMO |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Tripos | , | Bought by Certara |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| ApcinteX | , | Centessa Company |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Silence Therapeutics | London, UK | RNAi |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| Protalex | , | Failed 2018, shell |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| Signalife | , | Renamed Heart Tronics |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Alan Laboratories | , | Website gone, Jan 2019 |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Biovail | , | Merged with Valeant |
| Novoresearch | , | Gone 2014 |
| PreciThera | , | Website taken over, Dec 2021 |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| , | Acquired by Uniphar | |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| Avineuro | , | Website taken over Feb 2024 |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| , | Renamed Helyx Industries | |
| Able Labs | , | big FDA trouble, gone |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| Sprna | , | Website gone Jan 2020, no info |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Minimus Spine | , | Only real employee now full-time at another company |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| , | Renamed Cyclana Bio | |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| GeneVivo | , | Unknown Fate |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| CRI | , | Now BiomericsATL |
| Seeker Biologics | , | Shut down May 2023 |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| HpVac | , | Renamed Atopia Therapeutics |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| Astrum | Paris, France | Clinical Development CRO |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| Qualiber | , | Presumed inactive, website gone |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| CareDx | Brisbane, CA | Diagnostics |
| OpenClinica | Needham, MA | Clinical Study Software |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| AQEMIA | Paris, France | AI Drug Discovery |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| , | Acquired by BioIVT, Aug 2024 | |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Eurand | , | Now Aptalis |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| Biocorp | Issoire, France | Medical Devices |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| Sharp | Heerenveen, Netherlands | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| Medtronic | Warsaw, IN | Medical Devices |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| , | Website down Jan 2026 - May 2026 | |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Vega Therapeutics | , | Being acquired by Incyte, Jun 2026, $1.25B; Part of Star Therapeutics |
| Vanadis Laboratories | , | Gone 2018 |
| , | Acquired by Aptean, Oct 2016 | |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Coral Drugs | New Delhi, India | APIs |
| Evosep | Odense, Denmark | Automated Sample Prep |
| , | Renamed Silthera, Apr 2026 | |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| CRIO | Boston, MA | eClinical Software |
| Teva | Toronto, ON | Small Molecules |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| Zai Lab | Beijing, China | Small Molecules |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| Stago | Marseille, France | Diagnostics |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| Healionics | Seattle, WA | Biomaterials for devices |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| In Veritas Medical Diagnostics | , | Shell company |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Santen | Osaka, Japan | Ophthalmics |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| Lectus Therapeutics | , | Sold off product |
| Valitor | Berkeley, CA | Protein therapeutics |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| , | Merged with Vizgen, Oct 2024 | |
| PepVax | , | Gone 2024 |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Metabolex | , | Now CymaBay Therapeutics |
| Epigenetix | , | No annual report filed 2013-2019 |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Targenics | , | No website Mar 2020 |
| Eversana | Chicago, IL | Commercialization Consulting |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| Anacura | Evergem, Belgium | Analytical |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| ALTx Therapeutics | , | Small Molecule Therapies |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| ConjuChem | , | Bankrupt 2011 |
| Sage Science | Beverly, MA | DNA Fractionation |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Gone 2023, website taken over by a designer | |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| MikrobEX | , | Renamed Rebiotix |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Integer | Salem, VA | Medical & Surgical Devices |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| AxoTect | , | Phantom company |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Immunosyn | , | Charged with Securities Fraud |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Recon Therapeutics | , | Shut down Jun 2017 |
| RenovoRx | Mountain View, CA | Catheters |
| Roslin Cells | , | Renamed RoslinCT |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| REV Clinical | Bakersfield, CA | Clinical Trials |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| |
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Abbott | Princeton, NJ | Diagnostics |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Tapestry Pharmaceuticals | , | Gone |
| Calcionics | , | Shut down 2010 |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Apaxis Medical | , | Gone 2019 |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Station X | , | Website Gone Mar 2018 |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Sebia | Lisses, France | Electrophoresis |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| General Oncology | Brookline, MA | Cancer Therapies |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| , | Website down Dec 2025 - Mar 2026 | |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Aeres Biomedical | , | Gone Jul 2013 |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Cerimon | , | Gone |
| Origen Therapeutics | , | Gone |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| , | Acquired by Avania, Oct 2024 | |
| Medreich | Bengaluru, India | CDMO |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Lupin | Mumbai, India | Generics |
| Accellacare | Ames, IA | Clinical Research |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Compugen | Holon, Israel | Biologics |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| LifeMax | , | Part of AmMax |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Sure Genomics | , | Gone 2014? |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| G1 Therapeutics | , | |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| EsbaTech | , | Bought by Alcan |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Matritech | , | Assets bought by Matritech 2007 |
| Nizyme | , | Gone Jul 2015 |
| Proacta | , | Gone 2014 |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| DiagnoCure | , | Liquidated, Apr 2016 |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| , | Website taken over May 2026 | |
| Pharmazz | Greater Noida , India | Small Molecules |
| Nocimed | , | Renamed Aclarion |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| , | Website down Oct 2025 - Jan 2026 | |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Norgine | Vienna, Austria | Specialty Pharma |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Theramex | London, UK | Women's Health |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| Navinta | Ewing, NJ | Generics |
| Yposkesi | , | part of SK pharmteco |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| Nigra | , | Acquired by Vernalis |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| Supeira | , | Website gone Mar 2023 |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Eargo | San Jose, CA | Hearing Aids |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Locanabio | , | Shutting down late 2023 |
| Chaperone Therapeutics | , | Gone 2019 |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Western States Biopharmaceuticals | , | Website Taken Over |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Vernacare | Chorley, UK | Surgical Devices |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| FusionBio | , | Website down Sep 2025 |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| Excelimmune | , | Closed Jul 2016 |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| Genemo | , | Seems inactive, Jul 2024 |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Phenomyx | , | Gone Jun 2019 |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| |
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Breathometer | , | Product didn’t work, pivoted |
| SJ Pharma | , | Website gone, Nov 2018 |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Amplified Proteomics | , | Shut down Jan 2006 |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| , | Pivoted to defense, Feb 2026 | |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Facet Biotech | , | Bought by Abbott 2010 |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| Amadix | Valladolid, Spain | Diagnostic development |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| Targovax | , | Renamed Circio, Apr 2023 |
| Vistin Pharma | Oslo, Norway | Generics |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| OrthoData | , | Renamed Intellirod Spine |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Oncovista | , | Dormant 2016 |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Amstem | , | SEC problems |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| , | Renamed First Atom Therapeutics | |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| Calzada | , | Renamed Polynovo |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| CoreBiome | , | Merged into Diversigen |
| AB Science | Paris, France | Small Molecules |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| PolyTherics | , | Joined Antitope to become Abzena |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Acidophil | , | Gone late 2022 |
| TrueBinding | Foster City, CA | Biotherapeutics |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| Gilead | Mississauga, ON | Small Molecules |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| Integer | Alden, NY | Medical & Surgical Devices |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Triangle Insights Group | Durham, NC | Consulting |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| Heart Repair Technologies | , | |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| Asarina Pharma | , | Winding down Jul 2024 |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Phenomix | , | Shut Down 2011 |
| AddBIO | , | Gone Oct 2023 |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Diality | Irvine, CA | Hemodialysis System |
| 1859, Inc. | , | Shut down Jul 2023 |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| , | Renamed Cellixx, May 2026 | |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| AnaBioTec | , | Now Anacura |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| PregLem | , | Acquired by Richter, Oct 2010 |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| DyNAbind | , | Shut down Apr 2025 |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| Perceptive | Nottingham, UK | Medical Imaging |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| LeukoSite | , | Acquired by Millennium 1999 |
| Vanguard Therapeutics | , | |
| Novitium Pharma | East Windsor, NJ | Generics |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| , | Renamed Kyntra Bio, Jan 2026 | |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| QuantaBio | Beverly, MA | PCR equipment |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Ergomed | Zagreb, Croatia | Clinical Research |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| CranioVation | , | Shut down Jan 2022 |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| IQVIA | Parsippany, NJ | Clinical Research |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| FHC | Bowdoin, ME | Medical Devices |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| Mepha | Basel, Switzerland | Generics |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| Evidera | , | Acquired by PPD, 2016 |
| Mabcare Therapeutics | , | |
| American Regent | Shirley, NY | Generics |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Reach Separations | Nottingham, UK | Purification Services |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| Chromtech | Apple Valley, MN | Chromatography Products |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Spine View | , | Gone |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| , | Main employees gone for months as of Nov 2025 | |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Ventaleon | , | Shut down 2020 |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Niche Generics | Arlesey, UK | Contract Generics |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| , | Website down Jul 2025 - Dec 2025 | |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Menarini | L'Aquila, Italy | Small Molecules |
| BioParadox | , | Shut down Dec 2017 |
| Invibio | Cleveleys, UK | Implants |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| Medrobiotics | , | Bankrupt, May 2024 |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Quiescence Technologies | , | Website Gone |
| Immutics | , | Renamed TrueBinding |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| VersaPharm | , | |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Isis Biopolymer | , | Website taken over |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| , | ||
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Nesch, LLC | , | Website gone Oct 2018 |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Texcell | Frederick, MD | Contract Research |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| Nuvik Therapeutics | , | No website, very little info |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| Abbott | Altavista, VA | Nutrition |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Spirometrix | , | Renamed Spirosure |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| Analogic | Peabody, MA | Medical Imaging |
| VALOS | Genova, Italy | Clinical Statistics |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Alcon | Mississauga, ON | Eye Care Products |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| O-Ray pharma | , | Inactive Jun 2022 |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| Abgenix | , | Bought by Amgen 2006 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Refined Diagnostics | Münster, Germany | Lasers |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| Evoke Medical | , | Renamed DirectSync Surgical |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| GEROPHARM | Moscow, Russia | Large drug maker |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Ergomed | Surrey, UK | Clinical Research |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Turku Bioscience | Turku, Finland | Research Services |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Bioneeds | Bangalore , India | Contract Research |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| ASIT Biotech | , | Renamed DMS Imaging |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| Natera | San Carlos, CA | Prenatal Testing |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Aranscia | Houston, TX | Diagnostic Software |
| Cue Biopharma | Boston, MA | Immunotherapy |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| , | Acquired by QOL Medical, Nov 2025 | |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Roche | Schlieren, Switzerland | Small Molecules |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| TaliaPharm | , | Website gone, Jan 2018 |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| Elona Pharmaceuticals | , | Gone |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| DP Clinical | Rockville, MD | Clinical Research |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| , | Website down Jul 2025 - Jan 2026 | |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Riverain Technologies | Miamisburg, OH | Imaging |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| Tico Bio | , | Renamed Inso Biosciences |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| , | Renamed Cordica Medical, Jan 2026 | |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Delpharm | Tours , France | Contract Manufacturing |
| BioXpert | , | Website gone Mar 2017, employees gone |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| , | Acquired by Versiti, Jul 2023 | |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| LabConnect | Johnson City, TN | Lab Services |
| Kirgen | Shanghai, China | Lab Supplies |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| DNALite Therapeutics | , | Renamed Particella |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Bionsight | Seoul, Korea | Database For Research |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| Oxis International | , | Renamed GT Biopharma |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| Lucena | , | Failed |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| APSciences | , | Website gone Aug 2022 |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| , | Renamed Singulera, Nov 2025 | |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| Clinical Scientist Group | , | Website gone, employee gone |
| IQVIA | Lenexa, KS | Clinical Research |
| , | Website down Jan 2026 - May 2026 | |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| Arete Therapeutics | , | Out of Business |
| bioMerieux | Lombard, IL | Diagnostics |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| Quantificare | Suwanee, GA | Medical Imaging |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Biobase | , | Bought by Qiagen, May 2014 |
| iTherapeutics | , | Doubt they do anything |
| Aviv Biomedical | , | Shut down 2018 |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| , | Acquired by GNI Group, Jun 2026 | |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| Pathens | , | Website hijacked Sep 2020 |
| Sequoia Pharmaceuticals | , | Folded |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| NeuroNano Pharma | , | Gone 2018 |
| , | Liquidating Jan 2026 | |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Pristine Bioproduction | , | Not a going concern |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| ThauMDx | , | Closed down 2003, out of cash |
| Protara Therapeutics | New York, NY | Cell Therapy |
| , | Website down, CEO gone Apr 2026 | |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| South Coast Clinical Trials | , | Website gone |
| 149 Medical | , | Shut down Dec 2022 |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Archimedes Vascular | Birmingham, | Hypertension Devices |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| AdrenaCard | , | Gone 2019 |
| Verenium | , | Bought by BASF, Dec 2013 |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Nabla Bio | Cambridge, MA | Antibody Design |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Cerebroscience | , | One employee, website gone |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| Syneos Health | Newtown, PA | Clinical Development |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| Telephus Medical | , | Now Telephus Biosciences |
| NeoVentures | London, ON | Custom Aptamers |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Novonesis | Beijing, China | Enzymes |
| Vivid Genomics | , | Shut down Sep 2023 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Minimally Invasive Devices | , | Shut down |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| 14M Genomics | , | Shut down, Feb 2016 |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| Acumed | Beijing, China | Medical Implants |
| ImmuRx | , | Gone, not sure what happened |
| Alfasigma | Bologna, Italy | Small Molecules? |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| TumorEnd | , | Website gone Feb 2019 |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Applied NeuroSolutions | , | Gone |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Califia Bio | , | Shut down May 2020 |
| Curadigm | , | folded into Nanobiotix |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| DLK Medical Technologies | Dallas, TX | OTC |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Telo Genomics | Toronto, ON | Diagnostics |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| Masy Systems | , | fka Masy Biosystems |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| , | Website down Jun 2025 - Oct 2025 | |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| , | Website down Aug 2025 - Jan 2026 | |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| Protelica | , | Dissolved, Dec 2006 |
| Cetero Research | , | Renamed PRACS Institute |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| Silence Therapeutics | Berlin, Germany | RNAi |
| Lupin | Baltimore, MD | Generics |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| Ribocept | , | Defunct |
| Rad AI | San Francisco, CA | Radiology Software |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| Viatris (2) | Hyderabad, India | Small Molecules |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| , | Acquired by Lantheus, Jan 2025 | |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Roswell Biotechnologies | , | Shut down late 2022 |
| CTG Pharma | , | Gone |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| Cambrian Genomics | , | Shut down Dec 2017 |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| , | Shut down Jan 2024 | |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| Stago | Taverny, France | Diagnostics |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| SOLADIS | , | Acquired by Efor, 2021 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| AxioMed | , | President left in 2018, not registered in MA |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Endothelix | , | Now owned by American Heart technologies |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Snorx | , | Renamed Zelegent, May 2015 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| , | Website down Jan 2026 - May 2026 | |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Northstar Neuroscience | , | Dissolved |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| , | Website gone Feb 2026 | |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Omnia Biologics | , | Website gone Sep 2017 |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Divide and Conquer | , | Website gone Mar 2024 |
| 89bio | Rehovot, Israel | Liver Treatments |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Coating Place | Verona, WI | Drug Delivery Services |
| iKaryos Diagnostics | , | Gone |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| LyoTechnica | , | Gone |
| Sharp | Rhymney, UK | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| alphaSyx Therapeutics | , | Gone |
| Covenant Therapeutics | , | Gone |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| Sharp | Lee, MA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| ParinGenix | , | Gone, 2012? |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Stago | Maastricht, Netherlands | Diagnostics |
| Ventris Medical | Newport Beach, CA | Tissues |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| PDL BioPharma | , | Shut down early 2021 |
| Active Implants | , | Renamed NUsurface |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| Glialogix | , | Gone Nov 2017 |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| PredictImmune | , | Shut down Nov 2023 |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| Novotech | Seoul, Korea | Clinical Research |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| Piramal | Digwal, India | CDMO |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Bayer | Bitterfeld, Germany | Small Molecules |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Envisagenics | New York, NY | Software-based drug discovery |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Macrogen | , | Renamed Psomagen, 2019 |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Adheren | , | Gone, 2016 |
| PlaSalus | , | Amateurish looking |
| Outset Medical | San Jose, CA | Dialysis Device |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Eurogentec | Seraing, Belgium | Biologics |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Nvelop Therapeutics | , | |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| Karo Bio | , | Renamed Karo Pharma |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Conkwest | , | Website gone Dec 2015 |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| Gennova Bio | Pune, India | mRNA vaccine |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| , | Website down Sep 2025 - Dec 2025 | |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis la |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| Idience | San Francisco, CA | Cancer Therapies |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Apgene Bio | , | Shut down Oct 2020 |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| , | Website down Jul 2025 - Dec 2025 | |
| Medtronic | Minneapolis, MN | Medical Devices |
| GenEscence | , | Gone Jul 2013 |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Microsure | Son, Netherlands | Surgical Robots |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| , | Website down Aug 2025 - Jan 2026 | |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Syantra | Calgary, AB | Breast cancer blood test |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Cristers | Suresnes, France | Generics |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| Cilag | , | Joined J&J 1959 |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Vitrology | , | Acquired by SGS, May 2012 |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Genovis | Cambridge, MA | Nanoparticles |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Prolexys Pharmaceuticals | , | Website Gone |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| Certego Therapeutics | , | Seems gone May 2023 |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| CMC Biologics | , | Now part of AGC Biologics |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Ana-Gen Technologies | , | Gone post 2001 |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| Getinge | Fairfield , NJ | Medical Technology |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| , | No news Jun 2021 - Jan 2026 | |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Copley Scientific | Nottingham, UK | Test equipment |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Scintillant Bioscience | , | Gone May 2025 |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Vanquish Oncology | , | No news 2015-2021 |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Vernacare | Worksop, UK | Surgical Devices |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| , | Renamed Proxoma, Jan 2026 | |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| , | Acquired by Embecta, Mar 2026 | |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| , | Website down Oct 2025 - Feb 2026 | |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Redpoint Bio | , | Inactive |
| Vernacare | Bolton, UK | Surgical Devices |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Microislet | , | Bankrupt 2008 |
| Axenis | , | Acquired by genOway, Sep 2018 |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| AngioChem | , | All employees gone, no info, presumed gone |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| EXO Biologics | Liège, Belgium | Exosomes |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Piramal | Rabale, India | CDMO |
| Sinobioway | , | |
| , | Acquired by Canoa, Aug 2019 | |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| Alkem Labs | Mumbai, India | Generics |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| , | Renamed MindWalk, Sep 2025 | |
| Terumo Medical | Somerset, NJ | Medical Devices |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| , | Website down Nov 2025 - Apr 2026 | |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| , | Website down Oct 2025 - Feb 2026 | |
| BIOMODEX | , | Acquired by Mentice |
| Silere Medical Technology | , | Shut down Dec 2013 |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Biotix | San Diego, CA | Lab Consumables |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| Daré Bioscience | San Diego, CA | Women's Health |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Biokit | , | Rolled into Werfen |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| RNA Therapeutics | , | No website Mar 2020 |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| Maroon Biotech | , | Gone Sep 2010 |
| BioCydex | , | No info 2019 - Mar 2025 |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| Procos | Cameri, Italy | Contract Manufacturing |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| Ergomed | Krakow, Poland | Clinical Research |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Cytopeia | , | Acquired by BD, May 2008 |
| Avrygen | , | Website Gone, execs gone |
| Trek Therapeutics | , | Shut down Sep 2019 |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| AJES Life Sciences | , | Renamed L2P Research |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| MicroPort | Arlington, TN | Medical Devices |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| OriMAbs | , | Gone post 2022 |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Actium Biosystems | , | Gone 2013 |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| Sirana Pharma | , | Merged with Apexis Bio |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Adaptix | Oxford, UK | Medical imaging |
| , | Website down Oct 2025 - Feb 2026 | |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Antara Biosciences | , | Bankrupt 2007 |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| Accumed Systems | , | Dated website, cant find any employees |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| VIVUS | Campbell, CA | Small Molecules |
| Aliquot Solutions | , | Shut down Oct 2024 |
| TCXpress | , | Renamed BlueSphere Bio |
| Revotek | , | Website down May 2023 - Sep 2023 |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Trilations | Melbourne, Australia | Strategic Consulting |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Sitka Biopharma | , | Website gone Jan 2022 |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Medelis | Ypres, Belgium | Clinical Research |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Tribiosys | , | Appears defunct, likely late 2007 |
| Venclose | , | Acquired by BD, Dec 2021 |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| KynderMed | , | Renamed Prena |
| Ikano Therapeutics | , | Gone |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| ProPharma Group | Westlake, OH | Consulting |
| numares | Houston, TX | Clinical Diagnostics |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| Tarpon Biosystems | , | Gone by 2017 |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| XtalPi | Shanghai, China | AI Drug Design |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Genstruct | , | Now Selventa |
| , | Subsumed into Synoptics | |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| Santen | Osaka, Japan | Ophthalmics |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| Traversa Therapeutics | , | Bankrupt |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| X-Rx | , | Shut down Jun 2020 |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Axikin Pharmaceuticals | , | Closed per Google |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Proimmune | Oxford, UK | Immunology research products |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| Veracyte | South SF, CA | Cytology Diagnostics |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| Aviria Biosciences | , | Disappeared |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Pharmaron | Cardiff, UK | R&D Services |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| Accord Healthcare | Ahmedabad , India | Generics |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Ottobock | Königsee, Germany | Prosthetics |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| Hansa Medical | , | Renamed Hansa Biopharma |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Ximedica | Plymouth, MN | Medical Device Services |
| RxCelerate | Cambridge, UK | Contract Services |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| Ezose Sciences | , | Rebranded as S-bio |
| EndoInSight | , | Website taken over Sep 2021 |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Ho’ola Therapeutics | , | |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| Vernacare | Maple, ON | Surgical Devices |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Predictive Therapeutics | , | Renamed NeoTX |
| , | Renamed KadisBio | |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| Picoseq | , | Renamed Depixus |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Denk Pharma | Munich, Germany | Generics |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Cobalis | , | Basically Bust |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Nura | , | Acquired by Omeros |
| Resilience | San Diego, CA | Biomanufacturing |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| , | No info 2019 - Mar 2026 | |
| Laureate Pharma | , | Acquired by Gallus |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| , | Acquired by Epitype, Oct 2025 | |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| , | Website messed up, single employee, Dec 2025 | |
| Tecomet | Wilmington, MA | Implant Components |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| MURO PHARM | , | Dissolved, May 2007 |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| Allievex | , | Shut down Feb 2025 |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Prommune | , | |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Luye Pharma | Shanghai, China | Small Molecules |
| Otsuka | Rockville, MD | Small Molecules |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| Amivas | Waterford, Ireland | Antimalarial |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| , | Shut Down Dec 2024 | |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Commence Bio | , | Gone 2018 |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| Epigenesis Pharmaceuticals | , | Gone |
| , | Website down Dec 2025 - Apr 2026 | |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| , | Renamed Revr Jan 2026 | |
| Inspirata | North York, ON | Cancer Insights |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| AltaRex | , | Gone |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Voitheia Bioscience | , | |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Halo Genomics | , | Bought by Agilent |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| Getinge | Suzhou, China | Medical Technology |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| , | Reportedly Closed Mar 2026 | |
| Tethys Bioscience | , | Shut Down, late 2013 |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| UniteLabs | , | Shut Down |
| , | Shut down Jan 2024 | |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| , | Acquired by Altivera Medical, Mar 2026 | |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| Confer Health | , | Shut down 2021 |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| PharmaGap | , | Shut down 2013 |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Medtronic | Jacksonville, FL | Medical Devices |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Macusight | , | Effectively acquired by Santen, 2008 |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| JABio | , | Shut Down May 2021 |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Nexgenia | , | Gone Dec 2019 |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| SE3D | , | Renamed Seed Therapeutics |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| Accellix | Jerusalem, Israel | On-demand Assays |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Abcellute | , | Dissolved, Sep 2016 |
| , | Became part of Accelerator, Dec 2025 | |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Genecure | , | Shut down Sep 2021 |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| PegaOne | , | Centessa Company |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Viragen | , | Liquidated Oct 2007 |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| NNS Clinical Research | , | Gone |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| ZipBio | Seattle, WA | Compact Proteins |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Active Pass Pharmaceuticals | , | Gone |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| DL Develop | , | Website gone, Dec 2018 |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Avenge Bio | , | Shut Down Jul 2024 |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| InteguRx | , | Website taken over, Dec 2023 |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Ribonomics | , | Sold to MBL International |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| Fairway Medical Technologies | , | Website gone |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| Amigenics | , | Gone |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Ackley Hartnett | Moorestown, NJ | Tablet Machines |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Mendaera | San Mateo, CA | Medical Robotics |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| Vicus Therapeutics | , | Gone 2019 |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Auris Medical | , | Renamed Altamira Therapeutics |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Sciele Pharma | , | Bought by Shionogi |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Getinge | Växjö, Sweden | Medical Technology |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Keenova | Dublin, Ireland | Small Molecules |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Carticept Medical | , | Dissolved Feb 2020 |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| , | Website down Sep 2025 - Feb 2026 | |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| CTC | Uppsala, Sweden | Clinical Site Network |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Adrenergics | , | Gone Sep 2017 |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Orchestra BioMed | New Hope, PA | Medical devices |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Eleven P15 | , | Shut down |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| Ossis | , | 3D-printed orthopedic implants |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| Madera Biosciences | , | Shut down Aug 2020 |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Jetequip | Boucherville, QC | Fluid Handling |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| EpicGenetics | , | Seems gone Jan 2024 |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| Shionogi | Florham Park, NJ | Small Molecules |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Bicolor | Belfast, UK | Lab Assays |
| Omixon | Boston, MA | Next-gen sequencing products |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Theravance Biopharma | South SF, CA | Small Molecules |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| MJ Biopharma | Mumbai, India | Generics |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Altasciences | Harleysville, PA | Contract Research |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Elan | , | Bought by Perrigo, Dec 2013 |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Quartzy | Hayward, CA | Lab Management Software |
| , | Closed June 2024 | |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| Medispect | , | Shut Down 2013 |
| , | Filings late Jul 2022 - Jun 2026 | |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Semafore Pharmaceuticals | , | Gone? |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| NexMed | , | Now Apricus Bio |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| Alaeras | , | Dissolved Jan 2014 |
| COR Clinical Research | , | Shut down after owner passed |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| miR Scientific | , | Renamed miRNA Scientific |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| , | Renamed Aurevia | |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| TG Therapeutics | Morrisville, NC | Biologics |
| InvivoGen | San Diego, CA | Life Science Reagents |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| Roche | Basel, Switzerland | Diagnostics |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| , | Acquired by Generic Specialties, May 2016 | |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| , | Acquired by eurifins, Sep 2024 | |
| K2M | , | Acquired by Stryker, Nov 2018 |
| Acucela | , | folded into Kubota Vision |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| , | Website taken over, Nov 2025 | |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Medice | Iserlohn, Germany | Small Molecules |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Sojournix | , | Shut down Jun 2021 |
| Suvoda | Portland, OR | Clinical Trial Software |
| Codon Devices | , | Closed Apr 2009 |
| Syngene International | Bangalore, India | Contract Research |
| Hubot CDMO | South Bend, IN | Contract Filling |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| Bioenza | , | Website gone Sep 2017 |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| , | Pandemic era government spongers | |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| PnuVax | , | No news 2017 - Aug 2024 |
| , | Acquired by Xoma, Oct 2025 | |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| Antisoma | , | Became investment company |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| , | Website down Jun 2025 - Dec 2025 | |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Ergomed | Belgrade, Serbia | Clinical Research |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Pharmos | , | Gone |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| Salvat | Barcelona, Spain | Small Molecules |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| , | Shut down Jul 2025 | |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| , | Website down Jun 2025 - Dec 2025 | |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| , | Website down Dec 2025 - Apr 2026 | |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Intrexon | , | Renamed Precigen |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Veracyte | Austin, TX | Cytology Diagnostics |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Northfield Laboratories | , | Bankrupt 2009 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| MolPlex | , | Insolvent, 2016 |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Eco Quest | , | Now Cynata Therapeutics |
| Antitope | , | Now part of Abzena |
| Hygtia Therapeutics | , | |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| SelectX | , | Website hacked; No updates since 2011 |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| Avecia | , | Bought by Nitto Denko |
| , | Assets being sold off May 2026 | |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| , | Website down Jan 2026 - May 2026 | |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| Vie Diagnostics | , | Renamed Phoresa |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Hookipa Biotech | , | Now Hookipa Pharma |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Infinitopes | Oxford, UK | Vaccines |
| AbbVie | Waco, TX | Contract Manufacturing |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Borean Pharma | , | Gone |
| MerciaPharma | , | No updates 2014-2023 |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| NeuroproteXeon | , | Gone 2021 |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| KeraCure | , | Gone 2014 |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Acumed | Hampshire , UK | Medical Implants |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| Apharm | , | Now Biofarma Group |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Folia Biotech | , | Website Gone May 2018 |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Verus Pharmaceuticals | , | Dissolved |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| Profusa | Emeryville, CA | Real-time biosensors |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| , | Acquired by Glaukos, Aug 2025 | |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| Coldstream Laboratories | , | Bought by Piramal |
| Collgard Biopharmaceuticals | , | Gone |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Axonia Medical | , | Gone 2015 |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| , | Renamed Grey Matters Health, Apr 2026 | |
| Tides Medical | Lafayette, LA | Biologics |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| preclinics | Parma, Italy | Contract Research |
| AIBioTech | , | Assets auction, Aug 2017 |
| Lifebit | London, UK | Genetic Data Analysis |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| American Drug Co. | , | Renamed Five Star Products |
| Delpharm | Lille, France | Contract Manufacturing |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| 3B BlackBio | Bhopal, India | PCR products |
| Vedere Bio II | , | Shut down Mar 2023 |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Microbiotix | Worcester, MA | Small Molecules |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| Compugen | San Francisco, CA | Biologics |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Axplora | Mourenx, France | API manufacturing |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Verix Health | , | Renamed Serpex Medical |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| Piper Therapeutics | , | Website gone May 2020 |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| Sygene Technologies | , | Website gone Nov 2018 |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Website down Jan 2026 - May 2026 | |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Enzo Biochem | , | |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| Singulex | , | Shut down Jun 2019 |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| STARLIMS | Hollywood, FL | LIMS |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Haupt Pharma | , | Merged with Aenova |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Gilson | Middleton, WI | Lab Supplies |
| PsiThera | Watertown, MA | Oral Small Molecules |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Parexel | Harrow, UK | Clinical Research |
| Parabase Genomics | , | Presumed gone |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Neugenesis | , | Bought by Intrexon, 2011 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| Amachumu Bio | , | Shut down April 2021 |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| , | Renamed Orvida Pharma, Apr 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Huons | Seongnam, Korea | Small Molecules |
| Dynatherm Medical | , | Shut down 2012 or later |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Quintessence Biotech | , | Biomimetic Separation |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Algenix | , | MN Business revoked, Mar 2004 |
| Ergomed | Cologne, Germany | Clinical Research |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| R/D Clinical Research | , | Website Gone |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Oticon | Smørum, Denmark | Hearing Aids |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Intact Genomics | St. Louis, MO | PCR kits |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| AssureRx | , | Renamed Assurex Health |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Alte Biosciences | , | Gone, Apr 2016? |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| VistaMed | , | |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Avam | Odessa, FL | Clinical Diagnostics |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| , | Acquire by Savillex, Nov 2024 | |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| CO.DON | Leipzig, Germany | Cell Therapies |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| Amarin | Bridgewater, NJ | Small Molecules |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Batu Biologics | , | Gone 2019? |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Scios | , | Bought by JnJ, Feb 2003 |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| NeuMedics | , | Website taken over by massager sales |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| , | Renamed Hermes Biosciences | |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Getinge | Orléans, France | Medical Technology |
| Louisville Bioscience | , | Now LBIdx |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| Sicor Biotech | , | Bought by Teva 2004 |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| NuAire | Plymouth, MN | Lab Equipment |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Stromedix | , | Bought by Biogen Idec 2012 |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| , | Website down Dec 2025 - Apr 2026 | |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| ID Pharma | , | Acquired by I'rom Group |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| AAVLife | , | Renamed Annapurna |
| Deimos Biosciences | , | |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Arginox Pharmaceuticals | , | Apparently Gone |
| Pfizer | Clondalkin, Ireland | Biologics |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| Indero | Montréal, QC | Dermatology Clinical Research |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Lupin | Somerset, NJ | Generics |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Clinilabs | Eatontown, NJ | Clinical Research |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| Valneva | Lyon, France | Antibody Discovery |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| , | Website down Jul 2025 - Jan 2026 | |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Enterey | Irvine, CA | Life Science Consulting |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| , | Acquired by Hologic, Jan 2025, $350M | |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Waters | Milford, MA | Chromatography & Chemistry |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| , | being Acquired by Chugai, Oct 2025 | |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Clear Image Technology | , | Now CIT Ortho |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| Evonik Industries | Essen, Germany | API Manufacturing |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Boston Scientific | Marlborough, MA | Medical Devices |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Bio-Detail | , | Website gone Feb 2023 |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Human Genome Sciences | , | Bought by GSK |
| Typharm | Norwich, UK | Generics |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Activated Cell Therapy | , | Changed name to Dendreon |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Ampac Analytical | , | part of SK pharmteco |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| , | Renamed WallabyPhenox | |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| , | Renamed Solario Bio | |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Sampled | Motherwell, UK | Biostorage |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| MYcroarray | , | Renamed Arbor Biosciences |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Xcelthera | , | Shut down, Apr 2021 |
| QuantumBio | State College, PA | Protein characterization software |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| XBiotech | Austin, TX | Antibody Therapy |
| Alumis | South SF, CA | Autoimmune Treatments |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| Trilobio | San Francisco, CA | Lab Automation |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| Supratek Pharma | , | Website gone Sep 2017 |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| OD-OS | Irvine, CA | Retinal Laser |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Cognis Corp | , | Acquired by BASF 2010 |
| Salvat | Madrid, Spain | Small Molecules |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Getinge | Getinge, Sweden | Medical Technology |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| , | Part of Genesis Biotechnology Group | |
| DiagnoSearch | Thane, India | Clinical Research |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| May Health | Paris, France | Ovulation Restoration Therapy |
| Obecure | , | Inactive, no info |
| Cell Technology | , | Acquired by ICT |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Blansett Pharmacal | , | Gone Jan 2019 |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Indena | Milan, Italy | CDMO |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| GeoVax | Smyrna, GA | Vaccines |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Narus Development Solutions | , | Gone |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Infinity Bio | Baltimore, MD | Reactome Services |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Cytecs | Münster, Germany | Cell Analysis |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Horiba Instruments | Irvine, CA | Equipment |
| , | Website down Jan 2026 - May 2026 | |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| , | Acquired by Merck, May 2026, $6.67B | |
| Plureon | , | Website gone, one employee after 17 years |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| GeneProt | , | Shut down Apr 2005 |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| Grunenthal | Quito, Ecuador | Small molecules |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| , | Website down Sep 2025 - Dec 2025 | |
| Altheos | , | Closed |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Progyny | New York, NY | IVF products |
| Kentucky Bioprocessing | , | Now Kbio |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Par Health | St. Louis, MO | Generics |
| Ingenetix | Wien, Austria | PCR Products |
| Eyetech | , | Website Gone 6-16-12 |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Qualicaps | Whitsett, NC | Capsules |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Wepredic | Saint Gregorie, France | Cell Lines |
| Stelvio Oncology | , | Gone late 2019 |
| Calixar | Lyon, France | Membrane Proteins |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Tyrian Diagnostics | , | Gone 2012 |
| , | Website down Jul 2025 - Oct 2025 | |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Gene Express Inc | , | bankrupt? |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| Celerion | West Conshohocken, PA | Clinical Research |
| CureGene | Shanghai, China | |
| DNA Worldwide | Frome, UK | DNA Testing |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| NeuroPharm | , | Liquidated 2010 |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| Klogene Therapeutics | , | Gone 2019? |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| , | Renamed SylamoreBio | |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Alltrna | Cambridge, MA | tRNA therapies |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| Sepracor | , | Now Sunovion |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Actylis | Port Washington, NY | Raw Materials |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Emmes | Rockville, MD | Clinical Research Organization |
| Alliances Catalyst | , | Liquidated |
| bioMerieux | Durham, NC | Diagnostics |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| KBioSim | , | Website down Dec 2017-May 2018 |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| MitoStem | , | Seems gone |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| Lannett | Trevose, PA | Generic Small Molecules |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| Resilience | Alameda, CA | Biomanufacturing |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Iquity Labs | , | Merged into Decode Health |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Xencor | San Diego, CA | Antibody Discovery |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| Formation Biologics | , | Rebranded as Forbius |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| Nexus BioPharma | , | No news 2017-2022 |
| NeuClone | Sydney, Australia | Biosimilars |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| PRA International | , | Now PRA Health Sciences |
| Oxehealth | , | Pivoted to mental health platform |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| MeiRui Pharma | , | Bought by GSK |
| LFB | Paris, France | Plasma derived drug products |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Maxivax | , | Renamed Release Therapeutics |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| Biovays | , | Website Gone |
| , | Renamed Verge Labs, May 2026 | |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Biotium | Fremont, CA | Fluorescent Reagents |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| ClinOne | Needham, MA | Clinical Patient Platform |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| , | ||
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| , | Website down Oct 2025 - Jan 2026 | |
| Hikma | London, UK | Medication Delivery |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| ERT | , | Renamed Clario, Nov 2021 |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Moximed | Fremont, CA | Joint treatment |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| Rho | Durham, NC | Clinical Research |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| Pharmaron | Beijing, China | R&D Services |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| , | Website down Dec 2025 - Apr 2026 | |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| CG Therapeutics | , | Dissolved Jul 2013 |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Anvyl | , | Website gone Jan 2021 |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Dexcom | San Diego, CA | Glucose Monitors |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| OxStem | , | Shut down 2021; Oxford spinout |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Therabest | Seoul, Korea | iPSC |
| Createrna Science | Shanghai, China | Small Molecules |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| Tolerx | , | Shut Down 2011 |
| Solace Pharmaceuticals | , | Out of business 2011 |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| Sonexa Therapeutics | , | Closed 2013 |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Lusis | Hayward, CA | Diagnostics |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| EndoSphere | , | Gone pre-2011 |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| VasoRx | San Diego, CA | RNA delivery |
| LianBio | , | Winding down Feb 2024 |
| InnoCare | Nanjing, China | Cancer Treatments |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Pathwork Diagnostics | , | Closed 2013 |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| MILabs | Houten, Netherlands | Molecular Imaging |
| DelSite | , | Bankrupt |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| Convergen LifeSciences | , | Renamed Genprex |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| NuLife Sciences | , | Shell acquired for a security business |
| NTRC | , | Now Oncolines |
| Mithridion | , | Website Gone, Company appears to be as well |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Delta-Vir | , | Website down Mar 2023 |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| NeuMed | , | Website four years since update, no employees on LI |
| Inverness Medical | , | Renamed Alere 2011 |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Excaliard | , | Bought by Pfizer 2011 |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| Gennova Bio | Pune, India | mRNA vaccine |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Selten Pharma | , | Gone 2017 |
| NB Therapeutics | , | Gone |
| Kivu Bioscience | San Francisco, CA | ADCs |
| Kelliop | Newark, CA | Diagnostic Reader |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Convergen | , | |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| Isolagen | , | Reorganized as Fibrocell Science |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Dornier MedTech | Sillingy, France | Urology Devices |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| CMD Medtech | Columbus, OH | Medical Device Development |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| Streck | La Vista, NE | QC & Diagnostic Products |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| Inventiva | Daix, France | Small Molecules |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| , | Renamed Ladder Bio, Nov 2025 | |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Getinge | La Ciotat, France | Medical Technology |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| Abpro | Lexington, MA | Antibodies |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| Northway Biotech | Waltham, MA | Contract research |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| CardioCanary | , | Founders gone. Doubt it's active |
| Root Lines Technology | , | Renamed Samabriva |
| ProPharma Group | Bozeman, MT | Consulting |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Mindshare Medical | , | Renamed RevealDx |
| Combs Lab | , | Website gone Dec 2016 |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| ProPharma Group | Windsor, ON | Consulting |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| , | Shut down Mar 2026 | |
| Alfacell | , | Now Tamir Biotechnology |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| ObsEva | , | Shut down Feb 2024 |
| Serentis | , | Website Gone |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| , | Website down Jan 2026 - May 2026 | |
| MetaMorphix | , | Changed to Scidera Genomics |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Zambon | Bresso, Italy | Small Molecules |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Avatar Biotechnologies | , | Gone 2010 |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| ProPharma Group | Deerfield, IL | Consulting |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Novotech | Bangalore, India | Clinical Research |
| Tal Medical | , | Gone |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Genae Associates | , | Acquired by IQVIA |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| AniLocus | Germantown, MD | Preclinical CRO |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Epic Pharma | Laurelton, NY | Generics |
| Adroit Surgical | , | Defunct |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Samsara Sciences | , | Shut Down Mar 2020 |
| IntelligentMDx | , | Shut down Feb 2015 |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Leukosight | , | Gone, website is online pharmacy now |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Cytel | Pune, India | Clinical software, statistical services |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Myoposity Therapeutics | , | Gone |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Henderson Morley | , | Bankrupt |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Azopharma | , | Bankrupt, Apr 2010 |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| Resilience | Hamilton, OH | Biomanufacturing |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| PathAI | Boston, MA | AI Powered Pathology |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Crown Bioscience | Beijing, China | Drug Development |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| OraSure | Bethlehem, PA | Diagnostics |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| , | Acquired by Paradigm Health, Jan 2023 | |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| Oligasis | , | Changed named to Kodiak Sciences |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| , | Website down Jan 2026 - May 2026 | |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| nplex biosciences | , | Renamed Nomic Bio |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Velos | , | Acquired by WCG, Mar 2018 |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| Axplora | Raubling, Germany | API CDMO |
| Octapharma | Lingolsheim, France | Plasma Products |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Altasciences | Montréal, QC | Contract Research |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| Quanticate | Hitchin, UK | Clinical Research |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| NanoVector | , | Gone 2019 |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Recida Therapeutics | , | |
| , | Website down Nov 2025 - Apr 2026 | |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| , | Website down Jan 2026 - May 2026 | |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| Benchling | San Francisco, CA | Biotech Software |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Immerge BioTherapeutics | , | Founded 2000 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| Theragenics | Buford, GA | Medical Devices |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| , | Shut down Nov 2025 | |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| PluriCell | , | Renamed LizarBio |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| , | Now Nexus Spine | |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Orthologic | , | Now Capstone Therapeutics |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| Novotech | Shanghai, China | Clinical Research |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| Piramal | Turbhe, India | CDMO |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| , | Subsumed into Synoptics | |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Novarad | Provo, UT | Imaging Software and Technology |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Abbott | Donegal, Ireland | Diagnostics |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Prometheus Labs | San Diego, CA | Diagnostics |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| Genyous Biomedical International | , | Presumed Gone |
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| MSN Labs | Hyderabad, India | Generics |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Dundee Cell Products | , | Renamed DC Biosciences |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Gen-probe | , | Acquired by Hologic 2012 |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| BioTransplant Inc | , | Bankrupt, 2003 |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Inventprise | Redmond, WA | Vaccines |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| BostonGene | Waltham, MA | Biomedical Software |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| CD Genomics | Shirley, NY | Genomics Services |
| CorDx | San Diego, CA | Diagnostics |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Plexision | Pittsburgh, PA | Diagnostics |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Prime Biologics | , | Seems gone 2019 |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Cholestech | , | Now Alere |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| UVision 360 | , | Renamed Luminelle |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Abgent | , | Renamed Abcepta, 2019 |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Metenova | ZZ, Sweden | Mixers |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Takara Bio USA | San Jose, CA | Lab products |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Viva Biotech | Shanghai , China | Contract Research |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| , | ||
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Zars Pharma | , | Acquired by NuVo Research |
| Noeledge | , | Shut down Jul 2024 |
| OcuDyne | , | AMD Medical Device |
| StemBioSys | San Antonio, TX | Stem Cells |
| Noucor Health | Barcelona, Spain | Small Molecules |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| Anulex Technologies | , | Closed 2014 |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| , | Renamed Transcend, Feb 2022 | |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Arbovax | , | Gone |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Renamed Pixl.bio, Nov 2025 | |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| Agendia | Irvine, CA | Breast Cancer Assay |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| Lupin | Goa, India | Generics |
| TeutoCell | , | Renamed Xell, 2014 |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Corza Medical | Shanghai, China | Surgical Devices |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| Align Technology | Tempe, AZ | Teeth alignment |
| Ipsen | Signes, France | Small Molecules, Biologics |
| BrainScope | Bethesda, MD | EEG characterization |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Merix Bioscience | , | Renamed Dendrix |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Point Biomedical | , | Liquidated Jul 2008 |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Qrativ | , | Folded into nFerence |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Ketal Biomedical | , | Gone |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| , | Acquired by IQVIA | |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| Cambrian Bio | New York, NY | Small Molecules |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Hope Medicine | Pudong, China | Antibody Therapy |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Vali Nanomedical | , | Gone 2016 |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Anfiro | , | Shut down Dec 2019 |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Denizen Biologics | , | Shut down Mar 2023 |
| ApniCure | , | Gone 2017 |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| Revance | Nashville, TN | Movement Disorder Treatment |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| superDimension | , | Acquired by Covidien May 2012 |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| Serometrix | , | More of an aspiration than a company |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| , | Website down Jul 2025 - Jan 2026 | |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| Quench Bio | , | Wound down Mar 2021 |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| , | Acquired by Stryker, Sep 2024 | |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Protein Polymer Technologies | , | Basically Gone |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Spriaso | , | No news 2019 - May 2025 |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Otsuka | Tokushima, Japan | Small Molecules |
| PL Developments | , | Parts of website taken over |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Satoris | , | Bought by Rules-Based Medicine |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Scientia Advisors | , | Website gone Jul 2015 |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Roxall | , | No news 2019 - May 2025 |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| BioDevek | , | Formerly LabCentral, seems gone |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| SEQENS | Pune, India | Analytical method validation, API development |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| RFE Pharma | , | Gone 2019 |
| Polytherapeutics | , | Gone Jun 2018 |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| PepLib Biotech | Metuchen, NJ | Peptides |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| , | Shut down Sep 2025 | |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Metis Laboratories | , | |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Acrux | West Melbourne, Australia | Drug Delivery |
| PX Biosolutions | , | Gone |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Octapharma | Springe, Germany | Plasma Products |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Acretia | , | Gone |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| ERBC | Baugy, France | Non clinical CRO |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Kvvit Pharmaceutical | , | |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Invenra | Madison, WI | Antibodies and their derivatives |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Wacker | Munich, Germany | Polymers, Resins |
| MicroStem | , | Gone Jun 2017 |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| , | Acquired by BICO, Aug 2021, $15M | |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| NeuroTransit | , | Behind on taxes in CA |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| sRNA Dx | , | aka sRNAlytics |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| TetraScience | Boston, MA | Scientific Cloud Software |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| PsiOxus Therapeutics | , | |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| , | Gone Jan 2025 | |
| NanoBio Systems | , | Shut Down Jun 2022 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| , | Acquired by Takara Bio, Jan 2025 | |
| Biolab | Mississauga, ON | Small Molecules |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Tulyp Medical | , | Pressure-driven perfusion system |
| , | Website down Jan 2026 - May 2026 | |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| CTIBIOTECH | Meyzieu, France | Tissue Sample |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| , | Shut down Jul 2014 | |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| Cellnovo | , | Bankrupt, Jul 2019 |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Valor Biotechnology | , | Renamed Roivant |
| , | Website down Jan 2026 - May 2026 | |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Menarini | Dresden, Germany | Small Molecules |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Rinat | , | Bought by Pfizer 2006 |
| Duality Biologics | Shanghai, China | ADCs |
| Surepharm | , | Liquidating, Apr 2025 |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Veeva Systems | Dublin, OH | Life Science Software |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| EMKinetics | , | Seems inactive Feb 2021 |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| , | Website down Oct 2025 - Dec 2025 | |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| NovoMedix | San Diego, CA | Small molecules |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| tte laboratories | , | Acquired by Transcat |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Ceptyr | , | Out of business 2012 |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| Eccogene | Shanghai, China | Small Molecules |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Apnex Medical | , | Shut down, Aug 2013 |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Orbus Pharma | , | Website Gone |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Excelsyn | , | Bought by AMRI |
| Solvay | , | Bought by Abbott 2010 |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| ResMed | San Diego, CA | Medical Devices |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| Concerto HealthAI | , | Renamed ConcertAI |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Stellartech Research | Milpitas, CA | Electronic device development |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Cebix | , | Shut down, Feb 2015 |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| , | Shut down June 2024 | |
| Medley Genomics | , | Website for sale Feb 2021 |
| , | No news 2020 - Dec 2025 | |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| CellXplore | , | Gone |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Inovio Biomedical | , | Seems gone |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Serica Technologies | , | Bought by Allergan |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| CrelioHealth | Columbia, MD | LIMS |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Aikium | Berkeley, CA | AI Drug Discovery |
| VytronUS | , | Shut down Mar 2020 |
| Ebewe Pharma | , | Now Sandoz |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Claritas Genomics | , | Closed Jan 2018 |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Catalina Pharma | , | No info 2017-2022 |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| Trudell Medical | London, ON | Inhalation Devices |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Pangaea Pharmaceuticals | , | Became Zycos |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Alt Bioscience | , | Now PDx Biotech |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Axya medical | , | Gone 2012 |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Signant Health | Horsham, PA | eClinical Solutions |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Aethox Therapeutics | London, UK | Inhibitors |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Attenuon | , | Now Tactic |
| Promosome | , | Gone |
| Oak BioSciences | , | Shut down Nov 2024 |
| , | Website down Dec 2025 - Apr 2026 | |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| , | Website down Nov 2025 - Apr 2026 | |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| BioArra | , | Bought by VWR Nov 2016 |
| Getinge | Tournefeuille, France | Medical Technology |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| Ankon Technologies | Wuhan, China | Medical Devices |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Prominex | San Diego, CA | POC Diagnostics |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Dirui Industrial | Changchun, China | Automated Assays |
| arGEN-X | , | Older name for Argenx |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| NextPharma | Limay, France | Contract Research & Development |
| Neuroptix | , | Renamed Cognoptix |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Nanobac Pharmaceuticals | , | Gone |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| , | Website down Oct 2025 - Feb 2026 | |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Acrongenomics | , | No info since 2013, seems gone |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| , | No news 2022 - Mar 2026 | |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Alife | San Francisco, CA | AI-powered IVF |
| Indexus Biomedical | , | Shut down 2018 |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Apicore | Gujarat, India | API Development & Manufacturing |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| T-Ray Science | , | Renamed Verisante |
| CPI Global | , | Website gone Jun 2020 |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| Cato Research | , | Renamed CATO-SMS |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| Evalve | , | Owned by Abbot Vascular |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Madison Vaccines | , | Website gone Dec 2019 |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| KVK Tech | Newtown, PA | Generics |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| Recodagen | , | Gone Jun 2009 |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Lab901 | , | Bought by Agilent |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| NinePoint Medical | , | Seems gone Sep 2020 |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Ergomed | Madrid, Spain | Clinical Research |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| EyeTel Imaging | , | Gone Jul 2015 |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| Parion Sciences | Durham, NC | Mucosal Targets |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| XW Laboratories | , | Renamed XWPharma |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| JAMP Pharma | Boucherville, QC | Generics |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| CardiRen Biomedical | , | Gone Aug 2017 |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Novotech | Bangkok, Thailand | Clinical Research |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| AMR Bio | Brighton, UK | Antimicrobials |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| , | Shut down Oct 2025 | |
| Marpē Therapeutics | , | Professor sideline |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
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, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| , | Website down Oct 2025 - Feb 2026 | |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| AtCor Medical | , | Now part of CardieX |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| , | Website down Sep 2025 - Dec 2025 | |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Getinge | Mahwah, NJ | Medical Technology |
| Etubics | , | Rolled into ImmunityBio |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| ADS Biotechnology | , | Bankrupt 2014 |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
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Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| Crown Bioscience | San Diego, CA | Drug Development |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Pharmascience | Montréal, QC | Generics |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |