Taiwan - Biotech Companies - Career Pages
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Orochem | Naperville, IL | Reagents, Automation |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Minntech | , | Now Medivators |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
 |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| ThauMDx | , | Closed down 2003, out of cash |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| Alacrity Biosciences | , | Gone post-2011 |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| Westat | Rockville, MD | Clinical trial design, management, services |
| Orchestra BioMed | New Hope, PA | Medical devices |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Regenicin | , | Residential address, three employees, no money |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Northfield Laboratories | , | Bankrupt 2009 |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| Adheren | , | Gone, 2016 |
| Afferon | , | Gone, no info |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
 |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| Tethys Bioscience | , | Shut Down, late 2013 |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| , | Website down Jan 2026 - May 2026 | |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| Excaliard | , | Bought by Pfizer 2011 |
| , | Website down Feb 2026 - Aug 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| InterX | , | Acquired by NeoTX, May 2022 |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Imalux | , | Ceased Operations, Apr 2014 |
| Acumed | Madrid, Spain | Medical Implants |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Partner Therapeutics | Lexington, MA | Biologics |
 |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Cedilla Therapeutics | , | Shut down May 2023 |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Orthologic | , | Now Capstone Therapeutics |
| , | Website down Sep 2025 - Feb 2026 | |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Crown Bioscience | Taicang, China | Drug Development |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| Avivo BioOptics | , | Website down Dec 2022 |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| Theragenics | Buford, GA | Medical Devices |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
 |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Wacker | Amsterdam, Netherlands | Biologics CDMO |
| Senlang Biotechnology | Hebei, China | Cell Therapy |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| , | ||
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
 |
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| , | Website down Jul 2026; Linkedin gone Jul 2026; Filings late Aug 2025; fka AilseVax | |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Serica Technologies | , | Bought by Allergan |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| OraPharma | , | Owned by Valeant |
| , | Website down Dec 2025 - Apr 2026 | |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| AlphaMab Oncology | Suzhou, China | Biologics |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| Perlara PBC | , | Shut down Feb 2019 |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| Mindshare Medical | , | Renamed RevealDx |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Vante BioPharm | , | Rebranded at Sebra |
| , | Acquired by BICO, Aug 2021, $15M | |
| NascaCell | , | German Aptamer company, not sure of fate |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Capsigen | Vancouver, WA | AAV Vectors |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Orthofix International | Lewisville, TX | Medical Devices |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Nexgenia | , | Gone Dec 2019 |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| CorWave | Clichy, France | Blood Pumps |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| Grifols | Clayton, NC | Biologics |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Generex Biotechnology | , | Website gone Feb 2024 |
| DesignMedix | , | Shut down Aug 2020 |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Apoptos | , | Acquired by Receptos |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| , | Website down Dec 2025 - Apr 2026 | |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| Aspira Scientific | , | Gone Nov 2015 |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
 |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| Cerebroscience | , | One employee, website gone |
| Berg Pharma | , | Now just Berg |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| Optimata | , | Shut down May 2019 |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Bayer | Berlin, Germany | Small Molecules |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Ergomed | Frankfurt, Germany | Clinical Research |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| Ignis Therapeutics | Shanghai, China | |
| Abgent | , | Renamed Abcepta, 2019 |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Clarivate | London, UK | Vascularized organoids |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| ExcelseBio | , | Part of IntegrityBio |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Chaperone Therapeutics | , | Gone 2019 |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Coldstream Laboratories | , | Bought by Piramal |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Jet Life Sciences | Hyderabad, India | APIs |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| ADS Biotechnology | , | Bankrupt 2014 |
| Gangagen | Bangalore , India | Ectolysins |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
 |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| LC Technologies | , | Renamed EyeGaze |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| Trine Pharmaceuticals | , | Closed 2008 |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| Niramai | London, UK | AI-breast cancer detection device |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| NeuClone | Sydney, Australia | Biosimilars |
| Eleven P15 | , | Shut down |
| , | Website down Feb 2026 - Jul 2026 | |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| SFS | Madrid, Spain | Clinical Research Organization |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Ribonomics | , | Sold to MBL International |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Catawba Research | Charlotte, NC | Clinical Research |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| Octapharma | Vienna, Austria | Plasma Products |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| , | Website down Nov 2025 - Apr 2026 | |
| Bonenta | , | Website gone |
| Mendaera | San Mateo, CA | Medical Robotics |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
 |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| Slainte Bioceuticals | , | Gone |
| Lexogen | Vienna, Austria | RNA kits |
| Glenmark | Mumbai, India | Generic Small Molecules |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| , | Website down Jan 2026 - Mar 2026 | |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| CNCure | Jeollanam, Korea | Tumor-targeting Bacteria |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Apini Therapeutics | , | |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Flash website Jul 2026; LI gone Jul 2026 | |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| Masy Systems | , | fka Masy Biosystems |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Ablacon | , | Shut down Mar 2024 |
| , | Seems gone, Feb 2026 | |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| OriMAbs | , | Gone post 2022 |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| , | Website down Oct 2025 - Feb 2026 | |
| NutrigeneAI Biotech | Hong Kong, China | Vascular Regeneration Platform |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| , | Pivoted to defense, Feb 2026 | |
| Myrexis | , | Liquidating 2013 |
| Ameridose | , | Shut Down 2012 |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Genedata | Basel, Switzerland | Bioinformatics |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Baxter | Grosotto, Italy | Medication Delivery |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| GeneFab | Alameda, CA | Gene Therapy Services |
| , | No news 2021 - Sep 2025 | |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| , | Acquired by Tarsus Pharmaceuticals, Jul 2026, $75M + $490M milestones | |
| , | Website down Oct 2025 - Feb 2026 | |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
 |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| , | Acquired by Versiti, Jul 2023 | |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Artimplant | , | Bankrupt, 2013 |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Via Pharmaceuticals | , | Shell Company |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| Agile EndoSurgery | , | Gone |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| BINEX | Chungcheongbukdo, Korea | Biologics CDMO |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Biocoat | Horsham, PA | Medical Device Coatings |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Pharming Group | Leiden, Netherlands | Biologics |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| Alphatec Spine | , | Renamed Atec Spine |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| AlcaSynn | , | Renamed ChironWells |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Raze Therapeutics | , | Closed due to complicated biology |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| AdvaStim | , | Shut down, Dec 2017 |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| , | Now part of Exalta | |
| , | Stopped work Aug 2025, IP company | |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| , | Website down Mar 2026 - Aug 2026 | |
| Ingenix | Warsaw, Poland | AI Engine Connection |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| Cognosci | , | CEO has another job, doesn't seem serious |
| , | Acquired by Bruker, May 2024, €870M | |
| , | Website down Jul 2025 - Jan 2026 | |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Pharmaron | Xi'an, China | R&D Services |
| Calyx Pharma | Mumbai, India | APIs |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Indero | Montréal, QC | Dermatology Clinical Research |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| RS Medical | Vancouver, WA | Medical Devices |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| BrainScope | Bethesda, MD | EEG characterization |
| , | Acquired by HiRO, Aug 2023 | |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| HeartVista | , | Renamed Vista.ai |
| Kailo Pharma | , | |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Atanse | , | Website gone, May 2018 |
| MantraPharma | Lévis, QC | Generics |
| Piramal | Morpeth, UK | CDMO |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| CD Genomics | Shirley, NY | Genomics Services |
 |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| , | Acquired by BD, Feb 2022 | |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| NeuroTherapeutics | , | Gone |
| Adynxx | , | Website taken over Sep 2020 |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Merck KGaA | Singapore, Singapore | |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| AstraZeneca | New Haven, CT | Biologics |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Fuse Diagnostics | Cambridge, MA | Molecular Diagnostics |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| United Immunoassay | , | Business revoked Jan 2022 |
| , | Liquidated Jun 2025 | |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| Eargo | San Jose, CA | Hearing Aids |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Wepredic | Saint Gregorie, France | Cell Lines |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| Celixir | , | Shell acquired Dec 2023 |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Genometry | , | Shut down Dec 2019 |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| Immunogen (1) | , | Renamed ImmunogenX |
| Abbott | Altavista, VA | Nutrition |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| Medelis | Ypres, Belgium | Clinical Research |
| Accellacare | Downers Grove, IL | Clinical Research |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Abbott | Des Plaines, IL | Diagnostics |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| , | Website down Dec 2025 - Apr 2026 | |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| , | Outlicensed sole product Sep 2021 | |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Owkin | New York, NY | AI for Medical Research |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| nference | Cambridge, MA | Clinical AI |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Aeres Biomedical | , | Gone Jul 2013 |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Validant | , | Renamed Eliquent Life Sciences |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| , | Website down May 2025 - Jan 2026 | |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Sprna | , | Website gone Jan 2020, no info |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| , | Website down Aug 2025 - Jan 2026 | |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| TissueNetix | , | Gone Feb 2018 |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Cytokinetics | South SF, CA | Small Molecules |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Foghorn Therapeutics | Watertown, MA | Cancer Drug Discovery, Protein Degradation |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| , | Website down Nov 2025 - Apr 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| OD-OS | Teltow, Germany | Retinal Laser |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Vision Medicines | , | Gone 2017 |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| , | Acquired by Bora Pharmaceuticals, Oct 2024 | |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| , | Website down Mar 2026 - Jul 2026; LI gone Jul 2026 | |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| Cue Health | , | Shut down May 2024 |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Medistem | , | Bought by Intrexon Dec 2013 |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| Indocruit | , | Gone |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| Alumis | South SF, CA | Autoimmune Treatments |
| , | Seems unserious, Jul 2026; fka Cetazam Therapeutics | |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| , | No news Jan 2021 - Jan 2026 | |
| BioCydex | , | No info 2019 - Mar 2025 |
| PumasAI | Dover, DE | Pharmacology, Modeling Software |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| Delta-Vir | , | Website down Mar 2023 |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| DDL | Eden Prairie, MN | Device Testing |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| , | Website down Aug 2025 - Jan 2026 | |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| RFE Pharma | , | Gone 2019 |
| Predictive Biosciences | , | Closed 2013 |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Ankon Technologies | Wuhan, China | Medical Devices |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Elucid | Boston, MA | Arterial Analysis Software |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| NEC Oncoimmunity | , | Renamed NEC |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Resilience | East Norriton, PA | Biomanufacturing |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| , | Website down Dec 2025 - Mar 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| iovera | Tampa, FL | Cold-treatment for nerves |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| Hubot CDMO | South Bend, IN | Contract Filling |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| Abolis Biotechnologies | Evry-Courcouronnes, France | Microbial engineering to produce biosourced small molecules |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Divergence | , | Bought by Monsanto |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| , | No news Nov 2021 - Jul 2026 | |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Cytel | Pune, India | Clinical software, statistical services |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| Tasso | Seattle, WA | Blood-collection products |
| Kembiotix | , | No info, Aug 2022 |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Genetic Technologies Group | , | Renamed geneType |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Macrocure | , | Merged into Leap Therapeutics |
| , | Website down Aug 2026; LI gone Jul 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| BostonGene | Waltham, MA | Biomedical Software |
| , | Acquired by Xoma, Sep 2025 | |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| , | Acquired by Millipore, Dec 2010 | |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| JAMP Pharma | Boucherville, QC | Generics |
| Alte Biosciences | , | Gone, Apr 2016? |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Nano Oncology | , | Gone |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Tikva Allocell | Proteos, Singapore | Cancer and autoimmune therapies |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Getinge | Orléans, France | Medical Technology |
| Cell>Point | , | Cant find any confirmation they are active |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| Signalife | , | Renamed Heart Tronics |
| Saghmos Therapeutics | , | |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Cambridge Pharma | , | Rolled into parent, SMC |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| AbGenomics | , | Renamed Altrubio |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Hemanext | Avon, MA | Transfusion Technologies |
| restor3d | Durham, NC | 3D printed implants and devices |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Ergomed | Raleigh, NC | Clinical Research |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| SuraMedical | , | Most employees left, not registered in MN |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| , | ||
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| , | No news Mar 2021 - Jan 2026 | |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| Rho | Durham, NC | Clinical Research |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| XBiotech | Austin, TX | Antibody Therapy |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Sharp | Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Pharmaron | Tianjin, China | R&D Services |
 |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Vaxart | South SF, CA | Oral Vaccines |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| Novahep | , | Website down, Oct-Dec 2017 |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| MDQuest | , | Website Down Feb 2025 |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| , | Renamed Renew Biotechnologies, Jul 2026 | |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| SGS Quay Pharma | , | |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| MedinCell | Jacou, France | API Delivery Gel |
| EndoStim | , | Shut down Jan 2020 |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| Genemod | Edmonds, WA | Lab management software |
| , | Website down Sep 2025 - Dec 2025 | |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| , | Acquired by Sebia, Sep 2024 | |
| May Health | Paris, France | Ovulation Restoration Therapy |
| Sensys Medical | , | Old company, no website, presumed defunct |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| , | Part of Normec | |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| , | Renamed Aurevia | |
| , | Acquired by Adial Pharmaceuticals, Jun 2026 | |
| Inspirata | North York, ON | Cancer Insights |
| , | Acquired by IQVIA | |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| SteriTech | Sligo, Ireland | Process Equipment |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| , | Renamed Yicura, Jun 2026 | |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| InfraReDx | Bedford , MA | Medical Devices |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| Quantificare | Suwanee, GA | Medical Imaging |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Medrobotics | , | Bankrupt Jun 2022 |
| Ikano Therapeutics | , | Gone |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Bracco | Milan, Italy | Imaging |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| CoRegen | Houston, TX | Genetically Engineered T Reg Cells |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| Infectex | , | Website taken over May 2020 |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| , | Acquired by IQVIA | |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| YMC Process Technologies | Devens, MA | Purification Technology |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| , | No news Sep 2010 - Oct 2025 | |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Tolerx | , | Shut Down 2011 |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Ottobock | Duderstadt, Germany | Prosthetics |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Novotech | Hong Kong, China | Clinical Research |
| Theravance Biopharma | South SF, CA | Small Molecules |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| , | Acquired by MannKind, Oct 2025, $296M | |
| CombiGene | , | Stopped research Jan 2025 |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| , | Renamed BTgen Bio, May 2026 | |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| Epixis | , | Acquired by VBI Vaccines |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| , | No news 2021 - Jan 2026 | |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| Intercytex | , | Liquidated |
| Emergo by UL | Austin, TX | Medical device consulting |
| Protein Design Labs | , | Renamed PDL Biopharma |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| Piramal | Lexington, KY | CDMO |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Azkarra Therapeutics | South SF, CA | Small molecule modulators of DNA damage response (DDR) pathways |
| Castor | Claymont, DE | eClinical Trial Software |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| , | Acquired by Lonza, Apr 2017 | |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| Veryan Medical | Horsham, UK | Helical Stent |
| Octapharma | Springe, Germany | Plasma Products |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| , | Website down Aug 2026; LI gone Jul 2026; Co-work space/Residential Address, Sep 2022 | |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Immagene | , | Renamed Flindr Therapeutics |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Bhami's Research Laboratory | Mangaluru, India | Monoclonal Antibody Excipients |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| , | No news 2021 - Jul 2026 | |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| NextPharma | London, UK | Contract Research & Development |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Genialis | Boston, MA | Bioinformatics |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Valerio Therapeutics | Villejuif, France | Orphan Diseases, Decoy Oligonucleotides |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Novotech | Sydney, Australia | Clinical Research |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| SphynKx Therapeutics | , | Gone |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Boehringer Ingelheim | Shanghai, China | Small Molecules, Biologics, CDMO |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| Celerion | Vienna, Austria | Clinical Research |
| Natera | San Carlos, CA | Prenatal Testing |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| , | Assets bought by Bruker during restructuring, Jul 2026 | |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Getinge | Merrimack, NH | Medical Technology |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Sharp | Conshohocken, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Synergen | , | Bought by Amgen 1994 |
| Celula | , | Acquired by NeoSeq |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| , | No news 2019 - Jan 2026 | |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| BEAT BioTherapeutics | , | Closed 2017 |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| GT Molecular | Fort Collins, CO | PCR Kits |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| , | Owner gone, filings late Nov 2023 - Aug 2026 | |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| , | Acquired by Altaris, Mar 2025 | |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| Tensys Medical | , | Website gone Sep 2017 |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| NeuroVista | , | Website Gone, President has new job |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| , | Renamed Cerenome, Aug 2026 | |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| neoSurgical | , | Shut down 2017 |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| ImmuVen | , | Website gone, Dec 2015 |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Cytovale | South SF, CA | Sepsis Detection |
| , | No news 2019 - Sep 2025 | |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| Oxis International | , | Renamed GT Biopharma |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| ReactDx | Melbourne, FL | Wireless Monitors |
| , | Website down Dec 2025 - Apr 2026 | |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Remo CRO | , | Seems to be rebranded as Supeira |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| Anulex Technologies | , | Closed 2014 |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Oncology Clinical Research | , | Gone |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Galileo Research | , | No news since 2012, presumed gone |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| Velia Therapeutics | , | Shut down Jan 2025 |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| ImmuneXcite | , | Closed Oct 2017 |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Analog Pharma | Princeton, NJ | Generics |
| Axium Pharmaceuticals | , | Dissolved |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Tecomet | Bridgeport, MI | CNC Machining, Cutting Instruments, Orthopedics |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| , | Crypto Pivot, Nov 2025 | |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| MiNA Therapeutics | London, UK | Small activating RNA |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| Endotis Pharma | , | Founded in 2003. No info |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Attralus | Naples, FL | Amyloidosis Treatments |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| , | Renamed Novakand Pharma, Sep 2025 | |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Azano Biotech | , | Now Sandia Biotech |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Passage Bio | Philadelphia, PA | Gene Therapy |
 |
Cambridge, UK | Isogenica: VHH antibody discovery CRO. World's largest synthetic libraries, 100+ programmes, clinical candidates, discovery timelines cut in half. |
| Handa Pharmaceuticals | Tainan City, Taiwan | Specialty pharmaceutical development - generic and 505(b)(2) |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Chiromics | , | Website now a penny stock shill |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Constantiam Biosciences | Houston, TX | Clinical Interpretation Software |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Sea Medical Systems | , | Gone |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Bio-Processing Alliance | , | Website now for a training company |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| Neuroptix | , | Renamed Cognoptix |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Islet Sciences | , | Gone |
| SRI International | Menlo Park, CA | Independent Research |
| , | Website down Feb 2026 - Jul 2026 | |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| AniLocus | Germantown, MD | Preclinical CRO |
| TumorGen | San Diego, CA | Cancer Treatments |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| , | Website down Aug 2025 - Jan 2026 | |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| BioVascular | , | 2007 website as of Mar 2019 |
| , | Became part of Accelerator, Dec 2025 | |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| Gameto | New York, NY | Female Fertility Extension |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| Cato Research | , | Renamed CATO-SMS |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| , | Renamed Axiom Biosciences, Jun 2026 | |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Greppo Technologies | , | Renamed Verix Health |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Website down Jan 2026 - May 2026 | |
| Hepalink | Shenzhen, China | Heparin API |
| Apgene Bio | , | Shut down Oct 2020 |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Aimsn Medical | Beijing, China | Devices, Implants, First Aid |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| Drugabilis | Villejust, France | Druggability Services |
| Neural Analytics | , | Renamed NovaSignal |
| , | Website down, Dec 2025 - Jun 2026 | |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| TandemAI | New York, NY | AI to democratize the drug development process |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| GSK | Rueil-Malmaison, France | Small Molecules, Vaccines, Biologics |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| AxoGlia Therapeutics | , | Ran out of money |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| AbBaltis | Kent, UK | Plasmas & Sera |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| , | Website down Aug 2025 - Jan 2026 | |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| OncoQr | , | No news 2017 - Oct 2024 |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| , | Acquired by Eclipsebio, Jan 2026 | |
| SEQENS | Pune, India | Analytical method validation, API development |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Resprotect | , | No update since 2012 as of 2020 |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| , | Shut down Oct 2024 | |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| Pulse Biomedical | , | Distributor |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| , | Website down Mar 2026 - Jul 2026, LI gone Jul 2026 | |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Altan Pharma | , | Acquired by Ethypharm |
| Limerick Bio | , | Gone 2011 |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| , | Pivoted to AI Jul 2026; SenlangBio is subsidiary that does drug work | |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Piramal | Riverview, MI | CDMO |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| , | No news Jun 2021 - Jul 2026 | |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Senzime | Uppsala, Sweden | Devices |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| iBridge Medical | , | Website gone Jan 2020 |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| Macleods Pharmaceuticals | Gangtok, India | Generics |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| EndoSphere | , | Gone pre-2011 |
| Lavipharm | Peania Attica, Greece | Small molecules |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Syantra | Calgary, AB | Breast cancer blood test |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| STX-Med | , | Renamed Cefaly |
| Curadev | Noida, India | Immuno-oncology |
| ClearView | Newton, MA | Strategic Consulting |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Helix | San Mateo , CA | Genetic Testing |
| , | No news 2019 - Jul 2026 | |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| , | Acquired by Agilent, Sep 2024; Mallinckrodt sold unit to Private Equity, Sep 2019, $135M + $40M note + $75M contingents | |
| , | Website down Sep 2025 - Dec 2025 | |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| , | Website down Jun 2025 - Dec 2025 | |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Allermed Laboratories | , | Greer now responsible for all their products |
| CYTOO Cell Architects | , | |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Belmont Medical | Billerica, MA | Body Temperature Management Devices |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| Innerpulse | , | Gone maybe 2013 |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Tikcro Technologies | , | Liquidating 2021 |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Aixlie Pharmaceuticals | , | No idea what happened |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Acumed | Hillsboro, OR | Medical Implants |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Novo Nordisk | Tokyo, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| MSD | Ballydine, Ireland | Small Molecules |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| Ceptyr | , | Out of business 2012 |
| Solstice Oncology | , | |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| , | Website down Dec 2025 - Apr 2026 | |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Tecomet | Woburn, MA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Virscio | New Haven, CT | Contract Research & Consulting |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| Altasciences | Laval, QC | Contract Research |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| , | Website down Jan 2026 - May 2026 | |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| Meditrial | New York, NY | Clinical Services, Software |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| TrialStat Solutions | Montreal, QC | eClinical |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| , | Website down Jul 2025 - Jan 2026 | |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
 |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Angelica Therapeutics | , | Gone 2018 |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
 |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Strides Arcolab | , | Now just Strides |
| Neoneuron | San Antonio, TX | Neural Stem Cell Products for Brain Repair |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| Summation Bio | , | Shut down May 2023 |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Acologix | , | Closed Aug 2011 |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Biokit | , | Rolled into Werfen |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| Kastle Therapeutics | , | Closed May 2018 |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| TocopheRx | , | Gone before 2019 |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| LivaNova | London, UK | Nerve stimulation therapy |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| Fusion Biopharma | , | Presumed gone |
| Navinta | Ewing, NJ | Generics |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| Medochemie | Limassol, Cyprus | Generics |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| AB Science | Paris, France | Small Molecules |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Trinity Drug Partners | , | Gone |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| , | CEO, Li gone Aug 2026 | |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Diassess | , | Renamed Lucira Health |
| , | Renamed Cytonome, Jul 2003 | |
| , | Company gone Nov 2023, website taken by a game | |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| Proteintech | Manchester, UK | Research Antibodies |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics, CDMO |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| PrognosDx Health | , | Website gone Jun 2016 |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
 |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Altasciences | Cypress, CA | Contract Research |
| SYNkinase | , | Shut down |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| , | Website down Feb 2026 - Jul 2026 | |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| , | ||
| Advangen | , | Acquired by Cellmid, May 2013 |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| Antibiotice | Iasi, Romania | Generics |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| Tecomet | Wilmington, MA | EDM, Ultrasonics, Electrical Beam Welding, Vacuum Brazing |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Integer | Chaska, MN | Medical & Surgical Devices |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| HCW Biologics | Miramar, FL | Immunotherapy |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| SWITCH Biotech | , | Gone, 2020 |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Metronomia | Munich, Germany | Consulting & Data Management |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| Caidya | Shanghai, China | Clinical Research Organization |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| Lacerta Therapeutics | , | Shut down May 2024 |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| NeuTec Pharma | , | Shut down 2010 |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| MEDISPECTRA | , | Gone 2002 |
| Wacker | Halle, Germany | Biologics CDMO |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Pristine Bioproduction | , | Not a going concern |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| , | Website down Oct 2025 - Dec 2025 | |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| Squarex | , | Gone as of Oct 2021 |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Empatica | Milan, Italy | Seizure Detection |
| Cytoskeleton | Denver, CO | Research Products |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Prana Therapies | , | |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Gallus | , | Bought by Patheon, Aug 2014 |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| , | Acquired by Castle Biosciences, May 2025 | |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| AGI Therapeutics | , | Bought by Videra |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
 |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| PLC Medical Systems | , | Renamed RenalGuard |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| , | Renamed PKx Bio, 2026 | |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| Lupin | Maharashtra, India | Generics |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Acrux | West Melbourne, Australia | Drug Delivery |
| EPD Biotherapeutics | , | |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| Procognia | , | Website Gone, Layoffs 2014 |
| Proteologics | , | Apparently Gone |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| LifeSensors | , | Website hijacked Feb 2025 |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Northway Biotech | Waltham, MA | Contract research |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| , | Website down Apr 2026 - Aug 2026 | |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| , | Acquired by Eli Lilly, Jun 2026, up to $300M | |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
 |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SERB Pharmaceuticals | West Conshohocken, PA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Genomic Solutions | , | Acquired by Digilab |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| , | Website down Nov 2025 - Apr 2026 | |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Nanobiotix | Paris, France | Nanoparticles |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| APIE Therapeutics | , | Gone Jun 2025 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Almac | Souderton, PA | Pharmaceutical Services |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Epocal | , | Acquired by Alere, Feb 2013 |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Able Labs | , | big FDA trouble, gone |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Piramal | Sellersville, PA | CDMO |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| , | Website messed up, single employee, Dec 2025 | |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| LinaTech | Suzhou, China | Cancer treatment device |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| , | Subsumed into Cumulus Oncology | |
| CBH ClinTrials | , | now CenExelCBH |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| Martek Biosciences | , | Bought by DSM |
| , | No news 2019 - Aug 2026 | |
| Getinge | La Ciotat, France | Medical Technology |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Tecomet | Bristol, PA | CNC Machining, EDM, Finishing, Special Processes, Injection Molding |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| PolyMedix | , | Bankrupt Apr 2013 |
| Hybrigenics Services | , | Renamed ATON Group |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| TRIFARMA | Rozzano, Italy | APIs |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| , | Website down Jan 2026 - May 2026 | |
| Cytochroma | , | Acquired by Opko Health |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| Xtuit | , | Gone Jul 2018 |
| Silence Therapeutics | London, UK | RNAi |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| , | Website down Apr 2026 - Jul 2026, LI gone Jul 2026 | |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| , | Website down Oct 2025 - Feb 2026 | |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| Marpē Therapeutics | , | Professor sideline |
| , | Renamed Cyllene Therapeutics, Jul 2026 | |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Novita Healthcare | , | Renamed TALi Digital |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Qbiogene | , | No website. Fisher sells their products |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| TransCellular Therapeutics | , | Gone 2019 |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Global BioDevelopment | , | Website gone |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Mindflow Design | , | Now part of MPE |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| EpicGenetics | , | Seems gone Jan 2024 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| Graybug | , | Now Graybug Vision |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Alcon | Irvine, CA | Eye-Care Products |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Epana Bio | Berkeley, CA | Autoimmune Treatments |
| , | No news 2021 - Sep 2025 | |
| , | Website down Apr 2026 - Aug 2026 | |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Karo Bio | , | Renamed Karo Pharma |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Amplifold | , | DNA origami nanotechnology |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Alexis Biotech | , | Dissolved May 2015 |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| SpinalMotion | , | Website gone, 11-30-14 |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Elixir Pharmaceuticals | , | Gone |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Quench Bio | , | Wound down Mar 2021 |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| Padagis | Allegan, MI | Generics |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| , | Shut down Feb 2026 | |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| GliaMed | , | Website copyright 2009, seems defunct |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| British Biotech | , | Merged into Vernalis 2003 |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| InterShunt | Maple Grove, MN | Minimally Invasive Interarterial Shunts |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| XtalPi | Shenzhen, China | AI Drug Design |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| Orexia | , | Acquired by Centessa |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Formycon | Martinsried, Germany | Biosimilars |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| Ocean Therapeutics | , | Shut down June 2013 |
| Kentucky Bioprocessing | , | Now Kbio |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| , | Website down Feb 2026 - Jul 2026; aka Integrity Implants | |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Qool Therapeutics | , | Gone Jan 2021 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| Flownamics | Madison, WI | Automated Sampling |
| X2 Pharma | , | Website Gone |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| SCOLR Pharma | , | Closed Mar 2013 |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| , | LI gone Jul 2026; Website down Jun 2026 - Jul 2026 | |
| IMMY | Norman, OK | Fungal Diagnostics |
| Curamir Therapeutics | , | Shut down 2020 |
| Synergx | , | Owned by Morphogenesis |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| , | War company as of Aug 2026; Merged into purpose-created public shell Jul 2019 | |
| Epiomed Therapeutics | , | Gone |
| , | Website down Oct 2025 - Feb 2026 | |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Indago | , | Renamed Lazurite |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Plaxgen | , | Shut Down 2019 |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| Aethox Therapeutics | London, UK | Inhibitors |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Cambrian Genomics | , | Shut down Dec 2017 |
| , | Bankrupt May 2025 | |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Pharma Medica | Toronto, ON | Clinical Services |
| TTP Labtech | , | Renamed SPT Labtech |
| Ekteino | , | Closed, Dec 2016 |
| Biomax Informatics | , | Acquired by Labvantage |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Getinge | Mahwah, NJ | Medical Technology |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| Recopharma | , | Seems gone |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| , | Website down Jul 2025 - Dec 2025 | |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| , | Renamed Transcend, Feb 2022 | |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Cellution Biologics | Roswell, GA | Human Placental-based Tissue Allografts |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Baccuico | , | Renamed Bactobio |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| UMN Pharma | , | Liquidating Apr 2025 |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| , | Shut Down Dec 2024 | |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
 |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
 |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Prime Biologics | , | Seems gone 2019 |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| QC Ware | Paris, France | Molecular Discovery Platform |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Nile Therapeutics | , | Merged with Capricor |
 |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Genestack | Cambridge, UK | Genomics operating system |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Arcadia Science | Emeryville, CA | Evolution-based Drug Discovery Model |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| BGI | Copenhagen, Denmark | Diagnostics |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Mitos Pharmaceuticals | , | Website Gone |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Avontec | , | Gone |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Crown Bioscience | Loughborough , UK | Drug Development |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| , | Acquired by SERB Specialty, May 2020 | |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| UniteLabs | , | Shut Down |
| Univfy | Los Altos, CA | IVF reports |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| icometrix | Boston, MA | Imaging AI |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| FusionBio | , | Website down Sep 2025 |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| Bard1 | , | Renamed INOVIQ |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Radical Numerics | San Francisco, CA | Generative genomics |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Getinge | Delft, Netherlands | Medical Technology |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| Scinomix | Earth City, MO | Lab Automation Products |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Target Medicals | , | No news 2016 - Oct 2024 |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| Menarini | Dresden, Germany | Small Molecules |
| Altasciences | Auxvasse, MO | Contract Research |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Prominex | San Diego, CA | POC Diagnostics |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| PhytoMedical | , | Apparently Gone |
| , | Website down Jan 2026 - May 2026 | |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Davol | , | Acquired by Bard, 1980 |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Alliances Catalyst | , | Liquidated |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| , | Website down Jun 2025 - Dec 2025 | |
| AMR Bio | Brighton, UK | Antimicrobials |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| Stago | Taverny, France | Diagnostics |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| SineuGene | Beijing, China | Gene Therapy |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| AbbVie | Waco, TX | Contract Manufacturing |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Nocimed | , | Renamed Aclarion |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| , | Website taken over May 2026 | |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cerimon | , | Gone |
| , | Merged with Tecomet, Jan 2026 | |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| REV Clinical | Bakersfield, CA | Clinical Trials |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| Biotheneum | , | Gone |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| VersaPharm | , | |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Envisagenics | New York, NY | Software-based drug discovery |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| SL Pharma Labs | , | Website gone May 2018 |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| Boston Scientific | Marlborough, MA | Medical Devices |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| Waters | Milford, MA | Chromatography & Chemistry |
| Cytiva | Tokyo, Japan | Medical Devices |
| Lavipharm | Paris, France | Small molecules |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Curl Bio | , | Shut down Feb 2020 |
| , | Website down Jan 2026 - Mar 2026 | |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| , | Renamed Vaxanix, Jul 2026 | |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Nexus Genomics | , | Gone 2001 |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Agrisera | Vännäs, Sweden | Antibodies |
| Chromtech | Apple Valley, MN | Chromatography Products |
| , | Website down Oct 2025 - Feb 2026 | |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Librede | , | Acquired by Lygos, Jan 2020 |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Proteins and Peptide Management | , | Now Adocia |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| , | Website down Feb 2026 - Jul 2026 | |
| Reach Separations | Nottingham, UK | Purification Services |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| Existence Genetics | , | Bankrupt Dec 2012 |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| Stat One | Morrisvile, NC | eClinical |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Inspirata | Tampa, FL | Cancer Insights |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Helsinn | Dublin, Ireland | Small Molecules |
| Vernacare | Maple, ON | Surgical Devices |
| Global Cell Solutions | , | Gone Apr 2018 |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Vyriad | Rochester, MN | Immunovirotherapy |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| AtheroGenics | , | Assets Sold Off 2009 |
| Life Couriers | Munich, Germany | Diagnostics |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| CrelioHealth | Columbia, MD | LIMS |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| Seneb Biosciences | , | Gone 2017 |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| , | Shut down Sep 2025 | |
| PathAI | Boston, MA | AI Powered Pathology |
| , | Website down Apr 2026 - Aug 2026; aka Yuansisheng Peptide | |
| Acelyrin | , | Merged into Alumis, May 2025 |
| , | Merged with ABX-CRO | |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| BioMarin Pharmaceutical | London, UK | Biologics |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| , | Acquired by IQVIA | |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| icometrix | Leuven, Belgium | Imaging AI |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| Biogenes | Berlin, Germany | Antibodies |
| , | Website down Aug 2025 - Jan 2026 | |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| , | Shut down Oct 2024 | |
| Keenova | Hazelwood, MO | Small Molecules |
| Infinity Bio | Baltimore, MD | Reactome Services |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| , | Acquired by Viatris, Oct 2025 | |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| TRPblue | , | Shut down Dec 2023 |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| , | Became part of Accelerator, Dec 2025 | |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| Teva | West Chester, PA | Small Molecules |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Staburo | Munich, Germany | Clinical Services |
| , | Now Nexus Spine | |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| Genmab | Utrecht, Netherlands | Biologics |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| In Veritas Medical Diagnostics | , | Shell company |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| , | Pivoted to food, Feb 2026 | |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| OXON | Madrid, Spain | Real World Evidence |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| BioXpert | , | Website gone Mar 2017, employees gone |
| Advanced Genetic Technologies | , | No info |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| |
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| , | Website down Sep 2025 - Dec 2025 | |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| LunaDNA | , | Shutting down Jan 2024 |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| Verix Health | , | Renamed Serpex Medical |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| AC Diagnostics | , | Website from 2004 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Tolmar | Fort Collins, CO | Small Molecules |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| SOCIUM | Tokyo, Japan | Contract Research |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| Summit Therapeutics | Dublin, Ireland | Utrophin modulation technology |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| oRF Biologics | Tiffin, IA | Custom biologics, cells, media, antibodies, resins |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| , | Website down Jan 2026 - May 2026 | |
| Lab901 | , | Bought by Agilent |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| , | Percutaneous ventricular assist device | |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Genfit | Loos, France | Drug Discovery |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| Batu Biologics | , | Gone 2019? |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| , | Subsumed into parent, Intermountain Healthcare, Jun 2026 | |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| Forge Biologics | Grove City, OH | Biologics |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Cognosetta | , | Gone 2021 |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Altasciences | Everett, WA | Contract Research |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| MediLink Therapeutics | Suzhou, China | ADC |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Altasciences | Scott Township, PA | Contract Research |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| , | Winding down Jan 2026 | |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Evidera | , | Acquired by PPD, 2016 |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Genencor | , | Bought by DuPont |
| Tribiosys | , | Appears defunct, likely late 2007 |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| ChemRegen | , | Seems gone Jan 2022 |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Fortrea | Durham, NC | Clinical Research |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| , | Acquired by Cell Return, Dec 2019 | |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Nanosonics | Sydney, Australia | Ultrasound |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| Affivant | , | Part of Roivant |
 |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| , | Website down Sep 2025 - Dec 2025 | |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
 |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Gerostate Alpha | , | Shut down Dec 2024 |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| , | Website down, COO gone Oct 2025 | |
| InnoVoyce | Boston, MA | ENT Lasers |
| GenoMatix | , | Acquired by Intrexon |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| ModeX Therapeutics | Weston, MA | Biologics |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| ID Pharma | , | Acquired by I'rom Group |
| Xcede Technologies | , | Gone Jun 2020 |
| , | Website down Jun 2025 - Dec 2025 | |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| |
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Adela | Toronto, ON | Liquid Biopsy |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| NanoTess | Calgary, AB | Biocatalysts |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| , | Website down Dec 2025 - Jun 2026 | |
| RegenoCELL Therapeutics | , | Presumed gone |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Pear Bio | London, UK | Cancer Treatment Selection |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Vedere Bio II | , | Shut down Mar 2023 |
| Launchpad Therapeutics | , | |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Cibiem | , | Shut down May 2021 |
| Johari Medtech | Jodhpur, India | Medical Devices |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Mabcare Therapeutics | , | |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| , | Seems renamed to Lusis Biosciences | |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Dharma Biomedical | , | Website gone Nov 2022 |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Claryx | Long Island, NY | Hospital Infection Management Platform |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| ActivX Biosciences | , | Shut down Mar 2023 |
| Tulyp Medical | , | Pressure-driven perfusion system |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Sierra Neuropharmaceuticals | , | Not active |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Cilag | , | Joined J&J 1959 |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| , | Acquired by hVIVO, Jan 2025 | |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Verasonics | Kirkland, WA | Research Ultrasound |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| , | Shut down Oct 2023 | |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| , | Renamed Numerion Labs, Oct 2025 | |
| Vernacare | Chorley, UK | Surgical Devices |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| , | Renamed Iditarod Bio | |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Apalexo Biotechnologie | , | No info, probably gone |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| , | Website down Dec 2025 - Jun 2026 | |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| , | No business filings Feb 2014 - Jul 2026 | |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Siga | Corvallis, OR | Small Molecules |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| AMRI | , | Renamed Curia, Jul 2021 |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Novotech | Melbourne, Australia | Clinical Research |
| Northstar Neuroscience | , | Dissolved |
| Gennova Bio | Pune, India | mRNA vaccine |
| CoaguSense | Fremont, CA | Coagulation monitor |
| , | Website down Mar 2026 - Aug 2026 | |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| Neotech | , | Website down Jan 2019 |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| , | Website taken over Jun 2026 - Aug 2026 | |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| EhmetDx | , | Renamed Ehmet Health |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Champions Biotechnology | , | Now Champions Oncology |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Clinilabs | Eatontown, NJ | Clinical Research |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| Stada | Bad Vilbel, Germany | Generics |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| Talima Therapeutics | , | Closed 2011 |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Bestat Pharmaservices | Taipei, Taiwan | Clinical Consulting |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| AlloCure | , | Website Gone, Jul 2015 |
| Verici Dx | Cardiff, UK | Kidney Transplant Technology |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| Endologix | Irvine, CA | Medical Devices |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Nucryst | , | Bought by Smith & Nephew |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| , | Acquired by IASO Biotechnology, Jul 2026 | |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| Appili Therapeutics | Halifax, NS | Small molecule |
| Gentell | Yardley, PA | Wound Care |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| BiVACOR | Houston, TX | Heart replacement |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| BGI | Kobe, Japan | Genetic Testing |
| , | No news 2016 - Sep 2025 | |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| EndoInSight | , | Website taken over Sep 2021 |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Lombard Medical | Didcot, UK | Medical Devices |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| NexMed | , | Now Apricus Bio |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| Nuredis | , | Shut Down Apr 2021 |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Indexus Biomedical | , | Shut down 2018 |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Revvity | Waltham, MA | Diagnostics, Services |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Cellink | Blacksburg, VA | Bioprinting |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| US Labs | , | Bought by Labcorp |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Genuiti Therapeutics | , | |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| GNA Biosolutions | , | Now part of HP Health |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| , | Pivoted to Crypto, Oct 2025 | |
| Autotelic | , | Gone 2022 |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Macleods Pharmaceuticals | Pithampur, India | Generics |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| TRIFARMA | Chennai, India | APIs |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| GT Biologics | , | Renamed 4D Pharma Research |
| Clearbridge Biomedics | , | Renamed Biolidics |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| , | Acquired by Merit Medical, Jun 2023 | |
| Emmes | Rockville, MD | Clinical Research Organization |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| , | Website down Feb 2026 - Jul 2026 | |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| SDIX | Newark, DE | Diagnostics |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| , | Filings late Jun 2025 | |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Alizyme | , | Bankrupt 2009 |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| VasculoMedics | , | Gone 2019 |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| , | LI gone Jul 2026; Website emptied Jul 2026 | |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| |
Hamburg, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| bioMerieux | Durham, NC | Diagnostics |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| ZyStor | , | Bought by BioMarin, closed |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| , | Shut down Jul 2014 | |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| Norton Scientific | , | Website Gone, Oct 2014 |
| , | Renamed Ensera, Oct 2025 | |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Stryker | Mahwah, NJ | Medical Devices |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| , | Acquired by Uniphar | |
| Aviv Biomedical | , | Shut down 2018 |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| Station X | , | Website Gone Mar 2018 |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| Bacthera | , | Liquidating, Feb 2025 |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| NextGen Sciences | , | Defaulted, sued by employees |
| Entropia Biosciences | , | Shut Down June 2019 |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| , | Website down Oct 2025 - Jan 2026 | |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| , | New Apr 2023, website not ready Aug 2023 - Jun 2026 | |
| Piper Therapeutics | , | Website gone May 2020 |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| , | Shut down Dec 2024; aka ADITXT | |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| , | LI gone Jul 2026; Website down May 2026 - Jul 2026 | |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| , | Website taken over Aug 2026; fka Bioheart? | |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Stemnovate | Cambridge, UK | Research Cells |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| CellXplore | , | Gone |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| , | Acquired by Besins Healthcare, Jun 2026 | |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| TranS1 | , | Renamed Baxano Surgical |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| 121 Bio | , | Gone mid 2016 |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Avatar Biotechnologies | , | Gone 2010 |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| BA Sciences | Salem, NH | Analytical Services |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| , | Website taken over Jun 2026 - Aug 2026 | |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| Altheos | , | Closed |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Cellenion | Lyon, France | Single Cell Testing |
| Green Cross | , | Renamed GC Pharma |
| , | Website down Feb 2026 - Jul 2026 | |
| VitaCyte | Indianapolis, IN | Collagenase |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| Tecnimede | Lisbon, Portugal | Generics |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| Hematogenix | Tinley Park, IL | Pharma Services |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| NeuMedics | , | Website taken over by massager sales |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Spine View | , | Gone |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Topivert | , | Liquidating Jan 2021 |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Tripos | , | Bought by Certara |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| ATON | Shanghai, China | CDMO |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| Kirax | , | Website Gone |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Medtronic | Galway, Ireland | Medical Devices |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| Lifescience Dynamics | Toronto, ON | Clinical & Commercial Strategy |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Genyous Biomedical International | , | Presumed Gone |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| BenuBiopharma | , | Shut down Sep 2023 |
| , | Website down Mar 2026 - Aug 2026 | |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| Madeira Therapeutics | , | Gone. No info |
| Getinge | Ankara, Turkey | Medical Technology |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| Biotox Sciences | , | Renamed BTS Research |
| , | No news 2018 - May 2026 | |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| Lupin | Coral Springs, FL | Generics |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| Bionsight | Chuncheon, Korea | Database For Research |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| , | Website down Apr 2026 - Jul 2026, LI gone Jul 2026 | |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| BaseCure Therapeutics | , | |
| sRNA Dx | , | aka sRNAlytics |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| ParinGenix | , | Gone, 2012? |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| NEXGEL | Langhorne, PA | Hydrogels |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| Tecomet | Baden-Dattwil, Switzerland | Bone In-Growth Coating, Bearing Surface Solutions, Polymer Machining, Sterilized Packaging |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| , | Website down Oct 2025 - Feb 2026 | |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| Oak BioSciences | , | Shut down Nov 2024 |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| , | No news 2021 - Apr 2026 | |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| BioFluentLabs | , | Shut down July 2012 |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| Apotex | Toronto, ON | Small Molecule Generics |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| , | Website hijacked, LI gone Jul 2026 | |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| Aytu BioScience | , | now Aytu BioPharma |
| Ergomed | Zagreb, Croatia | Clinical Research |
| , | Website down Oct 2025 - Feb 2026 | |
| , | Website down Feb 2026 - Jul 2026; Virtual, US/Hong Kong | |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| Novotech | Taipei, Taiwan | Clinical Research |
| Vistin Pharma | Oslo, Norway | Generics |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Virtici | Seattle, WA | Product / Company Incubator |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| Mitokyne | , | Renamed Mitobridge |
| Mitokine Bioscience | , | Seems to be a research library now |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| SynAm Vaccine | , | Gone 2017 |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Bioclinica | , | Merged with ERT, 2021 |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| , | Seems to have shut down mid 2025 | |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| , | Website down Aug 2025 - Jan 2026 | |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| Pharminox | , | Website gone, Aug 2017 |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| Metrohm | Houston, TX | Lab Data Management Software |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| ApniCure | , | Gone 2017 |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Vega Therapeutics | , | Acquired by Incyte, Jul 2026, $1.25B; Part of Star Therapeutics |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| , | Website down Jan 2026 - May 2026 | |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Gensia Sicor | , | Renamed Sicor |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| , | Acquired by J&J, Dec 2025, $3.05B | |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| , | Merged with Vizgen, Oct 2024 | |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| Semafore Pharmaceuticals | , | Gone? |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| , | Website down Feb 2026 - Jul 2026 | |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Sokol GxP Services | Bensalem, PA | Equipment Qualification Services |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Omneuron | , | Closed |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| , | Renamed Athens Bioscience, Mar 2026 | |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| Veravas | Oakdale, MN | Diagnostics |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Newgen Biopharma | , | Suspended trading due to scandal |
| , | Acquired by Inizio, Dec 2025 | |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| , | Acquired by Collate, Aug 2025 | |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Lifescience Dynamics | London, UK | Clinical & Commercial Strategy |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| Smart Biosciences | , | Renamed sb-Peptide |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| Cryoniss | Deeside, UK | Bio Banking |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| , | Renamed NeuraNova, Jan 2026 | |
| , | Gone Jan 2025 | |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Makefield Therapeutics | , | Website Gone |
| Viva Biotech | Jiaxing , China | Contract Research |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| , | Renamed Solario Bio | |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Kimer Med | Nelson , New Zealand | Antivirals |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| Hemadvance | , | Gone |
| Accellacare | Knoxville, TN | Clinical Research |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Inventiva | Daix, France | Small Molecules |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Esper Therapeutics | , | Shut down 2016 |
| South Coast Clinical Trials | , | Website gone |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Oncodesign Services | Dijon, France | Preclinical services |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| BINEX | Seoul, Korea | Biologics CDMO |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| Pathwork Diagnostics | , | Closed 2013 |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| , | Acquired by Waters, 2023 | |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| Techne | , | Part of R&D Systems |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| , | ||
| CRI | , | Now BiomericsATL |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| NeoPharm | , | Merged with Insys Therapeutics |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| Stiefel | , | Acquired by GSK |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Immunosyn | , | Charged with Securities Fraud |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Stealth Therapeutics | , | Gone |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Kurin | San Diego, CA | Blood Collection Technology |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation pseudo-subsidiary | |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Cytopeia | , | Acquired by BD, May 2008 |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Doer Biologics | Hangzhou, China | Biologics |
| ROKIT | Seoul, Korea | Organ Regeneration |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| BioSyntech | , | Bought by Piramal |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Monobind | Lake Forest, CA | IVD |
| Zars Pharma | , | Acquired by NuVo Research |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Bioserv America | , | Shut down Aug 2024 |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| Akrivis Technologies | , | Gone Jun 2021 |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| , | Renamed Esco Healthcare, Jul 2026 | |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Boston Scientific | Galway, Ireland | Medical Devices |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| Protein Forest | , | Bought by Cell Biosciences |
| Apotech Consulting | London, UK | Life Science Consulting |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Marical | , | Website Gone |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| Alverix | , | Acquired by BD, Jan 2014 |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| PurMa Biologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| Adalid Sciences | Prague, Czech Republic | Nanoparticles for Drug Delivery |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| OmniBiome Therapeutics | , | Gone 2014? |
| Xenova | , | Acquired by Celtic Pharma |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| DP Clinical | Rockville, MD | Clinical Research |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| , | Shut down May 2026; Filed Chapter 11 bankruptcy Sep 2019 | |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| GemoPharm | , | No news 2017-2022 |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Aresus Pharma | , | Seems folded in to Dermago |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| , | Acquired by Generic Specialties, May 2016 | |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Acucela | , | folded into Kubota Vision |
| MakroCare | San Francisco, CA | Drug Development Partner |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| , | Closed June 2024 | |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Biotrofix | , | Gone, Dec 2014 |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| , | Acquired by GeneDx, May 2025, $33M + $18M Milestones | |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Suir Pharma | , | Bankrupt, May 2016 |
| Sharp | Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Supratek Pharma | , | Website gone Sep 2017 |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| NovoKera | , | Merged into Longevity Biomedical |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Amp Orthopedics | , | Shut down, 2012 |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| AdrenaCard | , | Gone 2019 |
| SVBio | , | Changed name to Lifecode |
| Stryker | Portage, MI | Medical Devices |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Lux Biosciences | , | Gone |
| MicroVention | , | Now Terumo Neuro |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Exalta | Bethlehem, PA | Orthopedic Devices |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Ergomed | Moscow, Russia | Clinical Research |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| TearScience | , | Acquired by J&J, Nov 2017 |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| , | Acquired by GNI Group, Jun 2026 | |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| Cyllene Therapeutics | Paris, France | Pinpoint Gene Therapy |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| SE3D | , | Renamed Seed Therapeutics |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| Medtronic | Shoreview, MN | Medical Devices |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| , | Renamed Motive Health, Jul 2023 | |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Calico | South SF, CA | Aging treatments |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| , | part of ElevateBio; fka LifeEDIT | |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | Website down Feb 2026 - Aug 2026 | |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Carver Biosciences | , | |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Zambon | Bresso, Italy | Small Molecules |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Anchen | , | Bought by Par Pharmaceutical |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| HpVac | , | Renamed Atopia Therapeutics |
| , | Acquired by Biogen, May 2026, $5.6B | |
| , | Website down Feb 2026 - Aug 2026 | |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| KXT bio | , | Shut down 2019 |
| ImmunoBiochem | , | No news 2018 -2023 |
| SaluMedica | , | Website Gone Jul 2015 |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Jetequip | Boucherville, QC | Fluid Handling |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Norgine | Milan, Italy | Specialty Pharma |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
 |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| Lung Bioengineering | , | Part of United Therapeutics |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Infinitopes | Oxford, UK | Vaccines |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| |
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| HackScience | , | Renamed Cytera, Nov 2018 |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Nanoferix | , | Renamed Pendant Biosciences |
| iCeutica | , | Seems gone, Jan 2022 |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Novo Nordisk | Bohumil, Czech Republic | Diabetes, obesity, liver disease and other therapeutic areas |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| Hepta | San Francisco, CA | Liquid Biopsy |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| Lenire Biosciences | , | Shut down Nov 2023 |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| PharmacoFore | , | Now Signature Therapeutics |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| , | Renamed Biocult, Jul 2026 | |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| DNALite Therapeutics | , | Renamed Particella |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| Agenix | , | Gone, Website taken over |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| , | Acquired by IQVIA | |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| , | Website hijacked Oct 2025 | |
| Abbott | Princeton, NJ | Diagnostics |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Sequoia Pharmaceuticals | , | Folded |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| Hypromatrix | , | Gone 2007 |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Aliquot Solutions | , | Shut down Oct 2024 |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| Sequel Pharmaceuticals | , | Gone |
| , | Liquidating, May 2026 | |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| GenQual | , | Inactive, Jun 2017 |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| Dendritix | , | Renamed Argos Therapeutics |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| , | Sold off assets Jun 2026; Filed bankruptcy, Mar 2026 | |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Exodon | , | Website taken over, Jul 2014 |
| Cogenics | , | Now Beckman Coulter Genomics |
| Locanabio | , | Shutting down late 2023 |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Alchemgen | , | Gone |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| AlloThera | , | Gone, 2018 |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| AB ANALITICA | Padua, Italy | Sequencing products |
| , | Website down Dec 2025 - Apr 2026 | |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Lung LLC | , | Renamed Lung Biotechnology |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Website down Aug 2025 - Jan 2026 | |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| amcure | , | Liquidated Sep 2024 |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Pharos Dx | , | Gone |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| AstraZeneca | Baar, Switzerland | Biologics |
| Medrio | San Francisco, CA | Clinical Trial Software |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Getinge | Englewood, CO | Medical Technology |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| , | No news 2021 - Jul 2026 | |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| Insulete | , | Website gone, presumed inactive |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Interdict | San Francisco, CA | Small Molecules |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| AmProtein | , | Presumed Gone |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Biophytis | Paris, France | Therapies for aging diseases |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| , | Acquired by Xoma, Oct 2025 | |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| DiObex | , | Shut Down 2009 |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| , | No news 2019 - Apr 2026 | |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| Immune Technology Corp | New York, NY | Virology research products |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| Satellos Bioscience | Markham, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| accuFD | , | Closed Dec 2017 |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing, CMO |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Eurosequence | , | Website gone Jan 2020 |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| Synthon | , | |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Curadev | Kent, UK | Immuno-oncology |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| , | Acquired by AstraZeneca, Dec 2025 | |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| CBM Biopharma | , | Shut down Nov 2020 |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Algenix | , | MN Business revoked, Mar 2004 |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Histide | Montpellier, France | Cell Recoding Molecules |
| KyooBe Tech | Leinfelden-Echterdingen, Germany | Contract Vaccines, Cell, Gene Therapy Manufacturing |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Vericel | Ann Arbor, MI | Cellular Products |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| Advantagene | , | Renamed Candel Therapeutics |
| Palleos | Wiesbaden, Germany | Clinical Services and Consulting |
| AbbVie | Dublin, Ireland | Medical Devices |
| InteguRx | , | Website taken over, Dec 2023 |
| Quratis | Cheongju, Korea | Vaccines |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Sure Genomics | , | Gone 2014? |
| Raytone Bio | , | |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Develco Pharma | Schopfheim, Germany | Generics |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| Amaranth Medical | , | Website gone, Apr 2019 |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Kendle | , | Acquired by INC Research 2011 |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| , | Liquidating Feb 2025 | |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| Nodality | , | Gone |
| , | Website down Dec 2025 - Jun 2026 | |
| Altair Therapeutics | , | Shut down Feb 2011 |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Adepthera | , | Shut down 2014 |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| Applied NeuroSolutions | , | Gone |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Bionovica | , | Website gone Dec 2022 |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Novonesis | Bangalore, India | Enzymes |
| Mytos | London, UK | Automated Cell Culture |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| Ortho Development | Draper, UT | Ortho Implants |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| C3 Jian | , | Now C3J Therapeutics |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| ProSci | Poway, CA | Antibodies, etc. |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| PegaOne | , | Centessa Company |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Algenics | , | Website gone Dec 2015 |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| Knopp Biosciences | , | |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Apcer Life Sciences | London, UK | Consultants |
| AbX Biologics | , | Renamed Abveris |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Biomedica | , | Now part of Oxford Biomedica |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| , | Gone Mar 2024 | |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| , | Website redirecting to Talon Group, Jul 2026 | |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| Sharp | Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| , | Renamed Cyclana Bio | |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| , | Seems to be News website, Jan 2026 | |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Stryker | Salt Lake City, UT | Medical Devices |
| Valor Biotechnology | , | Renamed Roivant |
| GeneEx | , | Now RevDia |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| RenovoRx | Mountain View, CA | Catheters |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| Ativa Medical | , | Renamed Immune IQ? |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Affinity Bio | , | Renamed MyriO Tx |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| IvWatch | Newport News, VA | IV infiltration detection |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| AcroCyte Therapeutics | San Carlos, CA | Scaffold-free 3D Cell Culture |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| , | Renamed Verge Medical, Mar 2025 | |
| Argolight | Pessac, France | Microscopes |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| , | Website down Nov 2025 - Mar 2026 | |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Ixchel Scientific | , | Renamed zPREDICTA |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| ExThera Medical | Martinez, CA | Blood filtration |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| TG Therapeutics | Morrisville, NC | Biologics |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Inventa Biosciences | , | Not Active |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Hemaquest | , | Gone by 2017, No info |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Saffron Therapeutics | , | Website down Oct 2021 |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Brain Vision | Morrisville, NC | EEG Systems |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| Instapath | Houston , TX | Automated Digital Pathology |
| , | Website down Feb 2026 - Jul 2026 | |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Streck | La Vista, NE | QC & Diagnostic Products |
| , | Website down Oct 2025 - Feb 2026 | |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| , | Product sold to Biodexa, Nov 2023 | |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| SeqRight | , | Acquired by GE Apr 2012 |
| Piramal | Hyderabad, India | CDMO |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Vascular Technology | Nashua, NH | Surgical Devices |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Avistone | Beijing, China | Precision Oncology |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| Smithers | Akron, OH | Contract Research |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| SGC Pharma | , | Website taken over, Nov 2016 |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| Sophiris Bio | , | Shut down May 2020 |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| PreDxion Bio | , | Renamed Refractal |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| Synteract | , | Website down May 2022 - Oct 2022 |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| ARCBio | , | Shut down 2014 |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Humanyx | , | No website, Seems gone |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Howfond | , | Website gone, Jul 2015 |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Ergomed | Cologne, Germany | Clinical Research |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| , | Website down May 2025 - Dec 2025 | |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| , | Website down Sep 2025 - Jan 2026 | |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Aplagen | , | No activity since 2008 |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| , | Acquired by Instem, Jul 2025 | |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| CardiRen Biomedical | , | Gone Aug 2017 |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Modern Biosciences | , | Renamed Istisso |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Xylo | Boulder, CO | Psychedelics |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Revance | Nashville, TN | Movement Disorder Treatment |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| CoMind | London, UK | Non-invasive brain monitoring system |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Amphora Medical | , | Shut down May 2019 |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| bespark*bio | Vienna, Austria | Consulting |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| JD Bioscience | Seoul, Korea | Small Molecules |
| X-Rx | , | Shut down Jun 2020 |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Sopharma | Sofia, Bulgaria | Generics |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| , | Website down Feb 2026 - Jul 2026 | |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| , | Website down Feb 2026 - Jul 2026 | |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Manhattan Pharmaceuticals | , | Gone |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| FocalTherics | Vaulx-en-Velin, France | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| Cadex Genomics | , | Shut down Jul 2024 |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| ChronTech Pharma | , | Became real estate company |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Noeledge | , | Shut down Jul 2024 |
| , | Acquired by Tecan, Aug 2021 | |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
 |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| Oncogen | , | Acquired by BMS, 1986 |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Promosome | , | Gone |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| 2 Bridge | Zoersel, Belgium | Consulting |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| , | ||
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Chromocyte | , | |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Biopar | , | Gone? |
| RecoRNA | Guangzhou, China | RNA-based Precision Medicine |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| CyBio | , | Merged into Jena, Jul 2014 |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Ambion | , | Bought by Applied Biosystems 2006 |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Avenir Pharma | , | No longer active |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| , | Filings late Mar 2025 - Feb 2026 | |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Novocell | , | Renamed Viacyte |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| , | Website down Dec 2025 - Apr 2026 | |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Neurologix | , | Bankrupt, Liquidation |
| Simbex | Lebanon, NH | Biomechanical devices |
| Medreich | Bengaluru, India | CDMO |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| , | Acquired by Stryker, Sep 2024 | |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Devsynthesis | Austin, TX | Chemistry CRO |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Terpenoid Therapeutics | , | Gone |
| Vericel | Cambridge, MA | Cellular Therapy |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| PreciThera | , | Website taken over, Dec 2021 |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Znomics | , | Bankrupt, Shell Company Now |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Metenova | ZZ, Sweden | Mixers |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| Menarini | L'Aquila, Italy | Small Molecules |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| RxGen | , | Renamed Virscio, Jan 2020 |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Enci Therapeutics | , | No website, business suspended by NC |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Élancé Therapeutics | , | Bispecific Antibodies |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Norgine | Hengoed, UK | Specialty Pharma |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| , | Website down Jul 2025 - Jan 2026 | |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Trek Therapeutics | , | Shut down Sep 2019 |
| , | Website down Nov 2025 - Apr 2026 | |
| CeQur | Greenville, SC | Insulin pump |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| AAVLife | , | Renamed Annapurna |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| Precision Virologics | , | Precision Virologics |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| , | ||
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Relevant Bio | , | Shut Down Oct 2023 |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| Yao Pharma | Chongqing, China | APIs, Generics |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| EmpowerPharm | , | Shut down |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| Genemo | , | Seems inactive, Jul 2024 |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Targovax | , | Renamed Circio, Apr 2023 |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| , | Website down Nov 2025 - Feb 2026 | |
 |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Allumiqs | Halifax, NS | Multiomics CRO delivering NULISA, LC-MS/MS, biomarker discovery and data insights. |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| Delpharm | Huningue, France | Contract Manufacturing |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Abcam | Waltham, MA | Antibodies |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Tecomet | Wilmington, MA | EDM, FPI, Passivation, Ultrasonics, Forging |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| Neurogene | Houston, TX | Genetic Therapies |
| Proscia | , | |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| , | Website down Oct 2025 - Feb 2026 | |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Lucena | , | Failed |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| OSI Pharmaceuticals | , | Bought by Astellas |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| MIFCOR | , | Founders both gone Feb 2021 |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| , | Website down Sep 2025 - Dec 2025 | |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| yuFlu | , | No website, no info Feb 2021 |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| , | Website down Dec 2025 - Apr 2026 | |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Delpor | Brisbane, CA | Drug Delivery System |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| Hemay Pharmaceutical | Tianjin, China | |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| , | Website down Apr 2026 - Aug 2026 | |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Takara Bio USA | San Jose, CA | Lab products |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| , | Website down Apr 2026 - Aug 2026 | |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Genta | , | Liquidation 2012 |
| Monroe Research | Monroe, NC | Clinical Trials |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| , | Acquired by Certara, Oct 2024 | |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Vodori | Chicago, IL | Commercial Content Software |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Moon Surgical | Paris, France | Robotic Surgery System |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| LyoGo | , | Website gone, all employees gone |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| , | Renamed WallabyPhenox | |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| , | Acquired by Alfasigma, Nov 2023, $800M | |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| IQVIA | Parsippany, NJ | Clinical Research |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| Mattson Jack | , | Now Kantar Health 2009 |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| EMKinetics | , | Seems inactive Feb 2021 |
| Sixal | , | SBIR, Presumed defunct |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| Emulate | Boston, MA | Organs-on-chips |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Septerna | South SF, CA | GPCR Drug Discovery |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| Neurophet | Seoul, Korea | AI-Image Processing |
| , | Website gone Feb 2026 - Jun 2026 | |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Profil | Neuss, Germany | Clinical Research Services |
| BioMS Medical | , | Gone? |
| Ultragenyx Pharmaceutical | South SF, CA | Small Molecules, Biologics |
| Pharsight | , | Merged with Tripos to become Certara |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| Nanogen | , | Now Epoch Biosciences |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Pathens | , | Website hijacked Sep 2020 |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Diploid Genomics | San Diego, CA | Diploid genome sequencing for AI Diagnostics |
| Biotrin International | , | Renamed Diasorin? |
| , | Assets acquired by Alexion, Feb 2011 | |
| Silence Therapeutics | Berlin, Germany | RNAi |
| Heraeus Medical | Dorado, PR | Medical Devices |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Berg | , | Acquired, Jan 2023 |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Revolver Therapeutics | Bath, UK | Transcription Block Survival Screen |
| tiakis Biotech | Kiel, Germany | Biologics |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Senseonics | Germantown, MD | Medical Devices |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| Jenken Biosciences | , | Shut down by 2014 |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| , | Website down Feb 2026 - Jul 2026 | |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| , | No news Aug 2019 - Jan 2026 | |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| Dorphan | , | Shut down so owner could spend more time skiing |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Tirupati | New Delhi, India | Generics |
| , | Merged with Nova Biomedical | |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| Synomics | , | Now Smithers Pharma Services |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| UniXell Biotechnology | Shanghai, China | Cell Therapy |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| Matritech | , | Assets bought by Matritech 2007 |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| , | Part of ICE Pharma | |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| Angiosyn | , | Acquired by Pfizer 2005 |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| , | Website taken over by compounding pharmacy, May 2026 | |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Angex Pharmaceuticals | , | Gone 2018 |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Hemanext | Lexington, MA | Transfusion Technologies |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Serotiny | , | Acquired by J&J, 2023 |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| , | Website down Aug 2026; Acquired by Novo Nordisk, May 2024, $1.1B | |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Gensignia | , | Website Gone, Aug 2017 |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| , | Acquired by Cambridge Bioscience, Feb 2026 | |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| , | ||
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| , | Website down Sep 2025 - Feb 2026 | |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| MeiRui Pharma | , | Bought by GSK |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| , | Renamed Turing Medical | |
| , | Acquired by Fujirebio, 2022 | |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| , | Renamed Fareon, Feb 2025 | |
| Serentrix | , | Seems gone Apr 2022 |
| UVision 360 | , | Renamed Luminelle |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Delpharm | Orléans, France | Contract Manufacturing |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Gerinda Therapeutics | , | Gone 2009 |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| , | Sold product Jul 2024; VP Sales gone Jun 2024 still on website Aug 2026 | |
| Repco Development Technologies | , | Renamed 3Dispense |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| , | Acquired by OraSure Technologies, Dec 2024, $25M | |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| Aerovance | , | Gone, don’t know where |
| Omnimmune | , | Shell company, trademark abandoned |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| Centricity Research | Toronto, ON | Clinical Research |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| ISM Therapeutics | , | Website Gone, no response from employees |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| , | Acquired by BioIVT, Aug 2024 | |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| , | Winding down Jan 2026 | |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| arGEN-X | , | Older name for Argenx |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Alchemia | , | Gone, late 2017 |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Xenomics | , | Now TrovaGene |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Gentel Bio | , | Ceased Operations 2012 |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Genecare | , | Gone |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| Icarus Medical | Charlottesville, VA | Knee Braces |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Profusa | Emeryville, CA | Real-time biosensors |
| Accium BioSciences | , | Shut down Oct 2024 |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Agendia | Irvine, CA | Breast Cancer Assay |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| EQL Pharma | Lund, Sweden | Generics |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| , | Filings late Jan 2026; No website May 2023 - Mar 2026 | |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Tecomet | Riviera Beach, FL | CNC Machining, EDM, Special Processes |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| MiRus | Marietta, GA | Spine Implants |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| , | Website down Jun 2025 - Dec 2025 | |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| Acidophil | , | Gone late 2022 |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Ribomic | Tokyo , Japan | Aptamers |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| HIPRA Biotech Services | Girona, Spain | Biologics CDMO |
| , | Renamed Novarna, Jul 2026 | |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Micell Technologies | , | Seems shut down 2019 |
| Aerogen | Galway, Ireland | Nebulizers |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| DoveTree Medicines | , | |
| , | Pivoted to defense contracting, Jan 2026 | |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Echo | San Diego, CA | Microscopy |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| Macleods Pharmaceuticals | Valsad, India | Generics |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Axcend | Lehi, UT | Chromatography Services |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Glen Research | Sterling, VA | Oligos |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Cellnovo | , | Bankrupt, Jul 2019 |
| |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Ergomed | Geneva, Switzerland | Clinical Research |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Avail Medsystems | , | Tech sold Mar 2024 |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| Veeva Systems | Dublin, OH | Life Science Software |
| Chrono Therapeutics | , | Shut Down 2019 |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Panther Orthopedics | , | Shut down Dec 2022 |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Medicomp | , | Renamed ReactDx |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Akela Pharma | , | Now PharmaForm |
| Accord Healthcare | Ahmedabad , India | Generics |
| Cellipse | , | Website taken over May 2020 |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| QuantumBio | State College, PA | Protein characterization software |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| , | Renamed Kyntra Bio, Jan 2026 | |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| Convergen | , | |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Amniox Medical | , | Folded into BioTissue |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| Vernacare | Worksop, UK | Surgical Devices |
| MSD | Brinny, Ireland | Small Molecules |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| , | Redirecting to Siemens, Feb 2026 | |
| , | Acquired by Aurinia Pharmaceuticals, Mar 2026; Assets spun out of Onyx Pharmaceuticals | |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Paige | New York, NY | AI Pathology |
| CoreBiome | , | Merged into Diversigen |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Liposonix | , | Bought by Medicis |
| Idience | Seoul, Korea | Cancer Therapies |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| , | Shut down Nov 2025, Tempus acquired assets | |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Vernacare | Newtown, UK | Surgical Devices |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| , | Gone Sep 2025 | |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| Actavalon | , | Shut down Dec 2020 |
| , | Acquired by Insphero, Nov 2025 | |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Innovative BioTherapies | , | Gone |
| HydroCision | North Billerica, MA | Saline Jet Device |
| Enzo Biochem | , | |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Securecell | Urdorf, Switzerland | Lab automation |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| CFL Biotech | , | Website gone Jul 2020 |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Dynacare | , | Bought by LabCorp 2002 |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| BRAND | Wertheim, Germany | Liquid Handling |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Mousera | , | Renamed Vium |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| DDi | Basel, Switzerland | Clinical Software |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| Phase Forward | , | Bought by oracle |
| ARTham Therapeutics | , | Shut Down late 2023 |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Averion | , | Now Aptiv |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| , | Website down Sep 2025 - Dec 2025 | |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Norgine | Madrid, Spain | Specialty Pharma |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| 7TM Pharma | , | Gone |
| OraSure | Bethlehem, PA | Diagnostics |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Lian Medical | Shanghai, China | Medical Devices |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Tecomet | Oregon City, OR | Contract Medical Device Work |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| NantCell | , | Renamed ImmunityBio |
| , | Website down Oct 2025 - Feb 2026 | |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Recodagen | , | Gone Jun 2009 |
| , | Website taken over Jun 2026 - Aug 2026; LI gone Jul 2026 | |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Createrna Science | Wuhan, China | Small Molecules |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| Cunde Medical | , | mRNA Cell Therapy combo |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| Bafna | Chennai, India | Generics |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| Bioquanta | , | Gone 2013 |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Sampled | Motherwell, UK | Biostorage |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| CONMED | Largo, FL | Surgical, Medical Devices |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| DNAMx | , | Renamed Adela |
| Pharmanovia | London, UK | Acquisition of Drugs |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Axplora | Raubling, Germany | API CDMO |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Maxivax | , | Renamed Release Therapeutics |
| Iomai | , | Bought by Intercell 2008 |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| BINEX | Incheon, Korea | Biologics CDMO |
| 3DBiopsy | , | Renamed Triopsy |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| CNCure | Seoul, Korea | Tumor-targeting Bacteria |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Tecomet | Arab, AL | Orthopedics CNC Machining |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Meissner | Castlebar, Ireland | Lab Systems |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Cure Foreward | , | Services suspended, May 2017 |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| ViraCyte | , | Renamed AlloVir |
| Sunol Molecular | , | Assets sold 2005 |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| Bio Processing | , | Bought by Bio-rad |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| , | Acquired by hVIVO, Dec 2019 | |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| AQEMIA | Paris, France | AI Drug Discovery |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Synlab | Munich, Germany | Clinical Lab Services |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| , | Now part of BioVendor | |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| Stago | Clarkston, GA | Diagnostics |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| , | Website taken over Feb 2026 | |
| Amakem | , | Website gone Dec 2015 |
| Sinovac Biotech | Beijing, China | Vaccines |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| QuantRx Biomedical | , | Shell company |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Celerion | Zurich, Switzerland | Clinical Research |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| , | Acquired by Eli Lilly, Jul 2026, $3.25B + $3.75M milestones | |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| Sinobioway | , | |
| , | Shut down Mar 2026 | |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Inimmune | Missoula, MT | Immunotherapeutics |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| MicroCam | , | Shut down 2015? |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Triage Wireless | , | Now named Sotera Wireless |
| Logan Medical Devices | , | Gone? |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| , | Acquired by mining company; fka Anew Medical | |
| Abbott | Irving, TX | Devices |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| , | Website down May 2025 - Nov 2025 | |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| GL Technologies | San Diego, CA | Calibration Services |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| , | Acquired by Paradigm Health, Jan 2023 | |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| , | Renamed LeonaBio, Jan 2026 | |
| Microfluidics | Westwood, MA | High shear fluid processors |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| VieVax | , | Gone Jan 2007 |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| , | Website down Dec 2025 - Apr 2026 | |
| Hookipa Biotech | , | Now Hookipa Pharma |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| AxioMed | , | President left in 2018, not registered in MA |
| Ennov | Paris, France | Software Solutions |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Silenseed | , | Renamed Silexion |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| , | Website gone Jan 2026 - Jul 2026; fka Sun BioPharma | |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| Korio | Doylestown, PA | RTSM Platform |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| XO1 | , | Bought by J&J, Mar 2015 |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| SNBL | , | Acquired by Altasciences |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Nereus | , | Website Gone late 2013, no info |
| Restek | Bellefonte, PA | LCGC Equipment |
| rhealth | Bedford, MA | Diagnostics |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| PeriGen | Cary, NC | Perinatal Devices |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Valneva | Lyon, France | Antibody Discovery |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Western Biologics | , | Dissolved, 1998 |
| GSK | Hamilton, MT | Vaccine additive |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Allsino Pharmaceutical | Hangzhou, China | Synthetic Pharma Manufacturing |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| Tal Medical | , | Gone |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| VWR | Radnor, PA | Lab Products & Chemicals |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| IncellDx | , | Renamed HealthBio AI |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| InnoCare | Shanghai, China | Cancer Treatments |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| , | No news 2019 - Oct 2025 | |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| , | Acquired by Sartorius, Apr 2025 | |
| Henderson Morley | , | Bankrupt |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| Altasciences | Overland Park, KS | Contract Research |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| MacuClear | , | Website gone Jan 2019 |
| Zetra Biologicals | , | Gone |
| Elix | Tokyo, Japan | AI Drug Discovery |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| TumorEnd | , | Website gone Feb 2019 |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| Dalex Biotech | , | Gone |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| DDL | Edison, NJ | Device Testing |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| Intellirod Spine | , | Sold Assets late 2020 |
| PharmAbcine | Daejeon, Korea | Antibodies |
| NeoCura | Beijing, China | Personalized Vaccines |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Zai Lab | Hong Kong, China | Small Molecules |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| Ally Therapeutics | , | Shut down early 2021 |
| , | No news 2017 - Apr 2026 | |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| Mirador Biomedical | , | Shut Down 2019 |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Chrysalis | Waltham, MA | GMP Space |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| , | Acquired by Medtronic, Jun 2026, $550M | |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| ProPharma Group | Bozeman, MT | Consulting |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| , | Website down Jan 2026 - May 2026 | |
| Roche | Penzberg, Germany | Diagnostics |
| Persomics | , | Gone 2019 |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Lumanity | London, UK | Consulting |
| , | Website down Jan 2026 - Apr 2026 | |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Telo Genomics | Toronto, ON | Diagnostics |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Niche Generics | Arlesey, UK | Contract Generics |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Kiecana Clinical Research | , | Now KCR |
| , | Acquired by IQVIA | |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| , | Acquired by Glaukos, Aug 2025 | |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Renamed Septal Solutions, Jul 2026 | |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| , | Website down Feb 2026 - Jul 2026 | |
| Gilead | Mississauga, ON | Small Molecules |
| , | Website down Jan 2026 - May 2026 | |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| Novonesis | Paraná, Brazil | Enzymes |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Vascular Genesis | , | Website gone Aug 2022 |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Genopis | , | Acquired by Wacker Feb 2021 |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| GlySens | , | Bankrupt Nov 2022 |
| Precision Research Institute | , | Shut down Apr 2024 |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| DelSite | , | Bankrupt |
| Sylentis | Madrid, Spain | RNAi Treatments |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Encorium | , | Bankrupt |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Concerto HealthAI | , | Renamed ConcertAI |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Luye Pharma | Shanghai, China | Small Molecules |
| OrthoData | , | Renamed Intellirod Spine |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Starkey | Eden Prairie, MN | Hearing Aids |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Aimsn Medical | Hong Kong, China | Devices, Implants, First Aid |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| Mabimmune | , | Merged with Neurimmune |
| In-Depth Genomics | , | Shut down Jan 2021 |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| , | Merged with Yarrow Bioscience, Jul 2026; fka Menlo Therapeutics | |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| Dipharma | Baranzate, Italy | APIs, Generics |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| Birdotech | Shanghai, China | CDRMO |
| Kumuda | , | Website gone Mar 2023 |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| Facet Biotech | , | Bought by Abbott 2010 |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| Aikium | Berkeley, CA | AI Drug Discovery |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| TaliaPharm | , | Website gone, Jan 2018 |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| VaxInnate | , | Dissolved Feb 2017 |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| TFS | Lund, Sweden | Clinical Research |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| NeuralInk | Fremont, CA | Neural Implants |
| Syndax Pharmaceuticals | New York, NY | Tumor Phenotype Modification |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Baxter | Jayuya, PR | Medication Delivery |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Promedior | , | Acquired by Roche, Feb 2020 |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| 1CellBio | , | Gone Jun 2019 |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| Sharp | Macungie, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| , | Shut down Fall 2025 | |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| CEL-SCI | Vienna, VA | Biologics |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Metabolex | , | Now CymaBay Therapeutics |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| , | Renamed Cordica Medical, Jan 2026 | |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Dey LP | , | Bought by Mylan 2007 |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| nplex biosciences | , | Renamed Nomic Bio |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Pharmaron | Cardiff, UK | R&D Services |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Cytecs | Münster, Germany | Cell Analysis |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| Eos Biotechnology | , | Gone 2005 |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| , | Acquired by Lilly, Feb 2026, up to $2.4B; fka Oroboros Bio | |
| Oticon | Somerset, NJ | Hearing Aids |
| , | ||
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| Intica Biomedical | , | Bankrupt 2014 |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| Macleods Pharmaceuticals | Himachal Pradesh, India | Generics |
| MSD | Carlow, Ireland | Vaccines |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Sharp | Bethlehem, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Delpharm | Reims, France | Contract Manufacturing |
| Ipsen | Dublin, Ireland | Small Molecules |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Apotex | Toronto, ON | Small Molecule Generics |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| OcuDyne | , | AMD Medical Device |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Spiriplex | , | Bankrupt, Mar 2023 |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Alper Biotechnology | , | Gone |
| Lupin | Somerset, NJ | Generics |
| Qardio | Covina, CA | Portable Heart Monitors |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| Anatomise Biostats | London, UK | Biostatistics |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| Sepiatec | Berlin, Germany | Separation Systems |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| CranioVation | , | Shut down Jan 2022 |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Lusaris Therapeutics | , | Shut down May 2023 |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Senetek | , | Not sure what happened, no site, seem gone |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| EMD Serono | Boston, MA | Biologics |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| TR Biosurgical | , | Website Taken Over |
| Santen | Nara, Japan | Ophthalmics |
| Epic Sciences | , | Shut down May 2025 |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| Excelya | Boulogne, France | Clinical Research |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| PhotoSonix Medical | , | Now a licensing outift |
| MaxThera | , | Shut Down Dec 2011 |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| , | Acquired by Frontage, Jul 2021 | |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| MilliporeSigma | Madison, WI | Small Molecules |
| Healx | Cambridge, UK | AI Drug Discovery |
| Balboa Biosciences | , | Gone 2010 |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| Optime Therapeutics | , | Acquired by Lippomix |
| Patronus Biotech | Singapore, | |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| , | Website down Oct 2025 - Feb 2026 | |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Sharp | Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| , | Website taken over Feb 2026 | |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Bayer | Barcelona, Spain | Small Molecules |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| DDi | London, UK | Clinical Software |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| ASIT Biotech | , | Renamed DMS Imaging |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Endogenx | , | Website Gone Dec 2013 |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| Sancilio | , | Now Micelle BioPharma |
| Viral Genetics | , | Now VG Life Sciences |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| GigaGen | San Carlos, CA | Immune therapeutics |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Cytheris | , | Out of business 2013 |
| Cytomatrix | , | Gone, Jun 2013 |
| , | Renamed SylamoreBio | |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| Balance Therapeutics | , | Gone late 2020 |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| Nuvation Bio | New York, NY | Oncology Treatments |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| , | No website updates since 2013 as of Dec 2025 | |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| HarkerBIO | , | Shut down Apr 2019 |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| algorithmRx | , | Now Venebio |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| Nura | , | Acquired by Omeros |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Snorx | , | Renamed Zelegent, May 2015 |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| Grove Instruments | , | Shut Down June 2017 |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| Engitix | London, UK | Human Organ Decellularization Technology |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| AcroCyte Therapeutics | New Taipei, Taiwan | Scaffold-free 3D Cell Culture |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| Tecomet | Santa Ana, CA | Orthopedics CNC Machining |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Innogen Pharmaceuticals | Shanghai, China | GLP-1, Biologics |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| LightMed | , | |
| Vernacare | Bolton, UK | Surgical Devices |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| Qurasense | , | Renamed Qvin |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| , | ||
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Advancells | Noida, India | Stem Cell Treatments |
| Apic Bio | , | Shut down Jan 2024 |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| , | Website down Jul 2025 - Dec 2025 | |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Baxter | Marion, NC | Medication Delivery |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Octane Biotech | Lucknow, India | Generics |
| American Drug Co. | , | Renamed Five Star Products |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| Cellworks | South SF, CA | Biosimulations |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| American Regent | Shirley, NY | Generics |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| Nya Cell Therapeutics | , | No info |
| Diagast | Loos, France | Transfusion Reagents |
| Inno Biologics | , | Website gone Jun 2020 |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| Dundee Cell Products | , | Renamed DC Biosciences |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| , | Website down Dec 2025 - Feb 2026 | |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| ProUroCare Medical | , | Gone |
| Deimos Biosciences | , | |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| Kirgen | Shanghai, China | Lab Supplies |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Octapharma | Stockholm, Sweden | Plasma Products |
| , | Renamed Revr Jan 2026 | |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Ximedica | Plymouth, MN | Medical Device Services |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| BioCrea | , | Website Gone, Feb 2018 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Parker BioConsulting | , | Sole employee is a professional board member |
| Fujifilm Biotechnologies | College Station, TX | Biologics Development & Manufacturing |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| Medrobiotics | , | Bankrupt, May 2024 |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| , | No news 2019 - Sep 2025 | |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| , | Renamed Medici Therapeutics, Dec 2024 | |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| Cytoplex Biosciences | , | Gone |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| , | Acquired by Siegfried, Jan 2026; Bought by J&J, resold Jul 2016 | |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Solexa | , | Merged with Illumina 2006 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Medtronic | Jacksonville, FL | Medical Devices |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| SIRGA Advanced Biopharma | , | Appears defunct |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Bayer | Mailand , Italy | Small Molecules |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| Celunol | , | Merged with Diversa to become Verenium |
| Avema Pharma | , | Bought by PL Developments |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Avecia | , | Bought by Nitto Denko |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Axonia Medical | , | Gone 2015 |
| , | Website down Feb 2025 - Dec 2025 | |
| NormOxys | , | Gone |
| OrphoMed | , | Shut Down 2022 |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| ICN Pharmaceuticals | , | Now Valeant |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| G6 Spine | , | Gone 2017 |
| Cyberval | , | Seems inactive Feb 2024 |
| Invenra | Madison, WI | Antibodies and their derivatives |
| Axcella Health | , | Renamed Axcella Therapeutics |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| , | ||
| Therics | , | Acquired by Integra |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Turku Bioscience | Turku, Finland | Research Services |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| , | Website gone Jan 2026 - Jul 2026; aka Weimou Biotechnologies? | |
| , | Website down Dec 2025 - Apr 2026 | |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| Acretia | , | Gone |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Surepharm | , | Liquidating, Apr 2025 |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| , | Website down Aug 2025 - Jan 2026 | |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Fujifilm Biotechnologies | Billingham, UK | Biologics Development & Manufacturing |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Altravax | , | Shut down 2016 |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| Cell Targeting Inc | , | Bought by Biotime |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| InCytu | , | Website gone Jul 2015 |
| Annova Chem | , | Gone, 2017 |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| SenzaGen | Lund, Sweden | Genomic Assays |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| Proxygen | Vienna, Austria | Cancer Therapies |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Medtronic | Memphis, TN | Medical Devices |
| Sermes | Madrid, Spain | Full Service CRO |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Actium Biosystems | , | Gone 2013 |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| PathoGene | , | Website taken over, Oct 2017 |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| , | Listed as shutdown on Google, Linkedin gone Jul 2026 | |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| LifeQual Pharmaceuticals | , | Website Gone |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Nephrion | , | Closed 2006? |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Sania Therapeutics | London, UK | CNS Treatments |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Hovione | Macau, China | Contract Manufacturing |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Sundia | , | Part of BioDuro |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| Circadiance | Export, PA | CPAP Mask |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Sarstedt | Nümbrecht, Germany | Lab products |
| OmniGuide | Billerica, MA | Surgical technology |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| EpiFinder | , | Gone May 2025 |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| STC Biologics | Newton, MA | Services |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Targenics | , | No website Mar 2020 |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Apollomics | Xiaoshan, China | Cancer medicines |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| Hasten Pharma | Hefei, China | Small Molecules |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Putney | , | Acquired by Dechra, Mar 2016 |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Avecris | Singapore, Singapore | Gene Delivery |
| , | Acquired by IMA Group, Oct 2025 | |
| Genocea Biosciences | , | Winding Down May 2022 |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Texcell | Frederick, MD | Contract Research |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| GIVAX | Boston, MA | GI Vaccines |
| Haini Pharmaceutical | Shanghai, China | Generics |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| CMC Biologics | , | Now part of AGC Biologics |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| CytoVera | , | Gone June 2017 |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| Aadigen | , | Renamed Aanastra |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| PharmedArtis | , | Gone 2019 |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| DC Biosciences | , | Shut down Jul 2023 |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Endovasc | , | Bankrupt 2008 |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Laureate Pharma | , | Acquired by Gallus |
| RegeneMed | , | No longer active in CA as of 2014 |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Moleac | Singapore, Singapore | Stroke Products |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| InvivoGen | San Diego, CA | Life Science Reagents |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Synovex | , | Renamed Adheron Therapeutics |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| , | Website down Mar 2026 - Aug 2026 | |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Borean Pharma | , | Gone |
| Bach Pharma | , | Shut down late 2023 |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| Aixa Bio | Cambridge, MA | AI genomics |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Alnis BioSciences | , | No info |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| , | No info 2019 - Mar 2026 | |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| METiS Technologies | , | |
| MerciaPharma | , | No updates 2014-2023 |
| Heraeus Medical | Changshu, China | Medical Devices |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| Ribopro | Oss, Netherlands | mRNA Services |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| Envision Genomics | , | Website gone Nov 2019 |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| Mardil Medical | , | Website gone Feb 2021 |
| inDNA Research Labs | , | Shut down 2015 |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| BridGE Genomics | , | Gone 2022 |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| Recon Therapeutics | , | Shut down Jun 2017 |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| Coating Place | Verona, WI | Drug Delivery Services |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| MicroPort | Clamart, France | Medical Devices |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| Attenuon | , | Now Tactic |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Allotera Therapeutics | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| Summit Therapeutics | Princeton, NJ | Utrophin modulation technology |
| Ectycell | , | Part of Cellectis |
| Pall | Port Washington, NY | Filtration |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Texcell | Evry, France | Contract Research |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| , | Website down Feb 2026 - Jul 2026 | |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Biobase | , | Bought by Qiagen, May 2014 |
| Trilobio | San Francisco, CA | Lab Automation |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| BioArctic | Stockholm, Sweden | CNS treatments |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Ergomed | London, UK | Clinical Research |
| Cromos Pharma | Portland, OR | Clinical Research |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Allelix | , | Merged with NPS |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Ottobock | Königsee, Germany | Prosthetics |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| , | Website taken over Mar 2026 | |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| Occam Design | Louisville, SS | Medical Device Development |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Tecomet | Oregon City, OR | Casting, Bone In-Growth Coating |
| Opsonix | , | Shut down May 2018 |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| CSSi | , | |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| Validation Associates | Herndon, VA | Validation Consulting |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Wiener lab | Capital Federal, Argentina | Reagents, Instruments, Software |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| AxoTect | , | Phantom company |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| , | Website down Mar 2026 - Aug 2026 | |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Mederi Therapeutics | , | Now Mederi-RF |
| GEROPHARM | Moscow , Russia | Large drug maker |
| Tecomet | Chelsea, MI | CNC Machining, Polymer Machining, Orthopedics |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| , | Renamed Precursion Biosciences, Jun 2026 | |
| Apofore | , | Shut down, Dec 2015 |
| , | Shut down Jan 2026 | |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| ClinArt | , | Now ClinArt MENA |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Caidya | Raleigh, NC | Clinical Research Organization |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| Roche | Schlieren, Switzerland | Small Molecules |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Verici Dx | Franklin, TN | Kidney Transplant Technology |
| Ximedica | San Francisco, CA | Medical Device Services |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| , | Website down Jan 2026 - May 2026 | |
| Keenova | Dublin, Ireland | Small Molecules |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Applied Molecular Genetics | , | Renamed Amgen |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Celerion | Tempe, AZ | Clinical Research |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| Core Dynamics | , | Gone |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| VAXX | , | Not sure what happened to them |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| BioPhyZica | , | Gone 2016 |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| preclinics | Parma, Italy | Contract Research |
| Texcell | Shanghai, China | Contract Research |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Daktari Diagnostics | , | Gone 2017 |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Celregen | Hangzhou, China | iPSC |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Newormics | , | Renamed vivoVerse, late 2022 |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| , | Website down Feb 2026 - Jul 2026 | |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| Valneva | Livingston, UK | Biologics Manufacturing |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Stemetix | , | Shut down Apr 2021 |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| Boston Scientific | Spencer, IN | Medical Devices |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| Summit Therapeutics | Miami, FL | Utrophin modulation technology |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| LipimetiX Development | , | Website gone, Jan 2020 |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| EpitoGenesis | , | Gone 2017 |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Spiden | , | Renamed Liom, Jul 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Mustang Bio | Worcester, MA | Immunotherapies |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Biodel | , | Merged with Albireo, Oct 2016 |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| Satya | Hyderabad, India | Small Molecule |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| , | Acquired by Instem, Jul 2025 | |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Jaleva Pharmaceuticals | , | Gone |
| JustRight Surgical | , | Renamed Bolder Surgical |
| PPD | Middleton, WI | Contract R & D, Consulting |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| Etubics | , | Rolled into ImmunityBio |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| , | Website taken over Jul 2026 - Aug 2026 | |
| Opentrons | New York, NY | Lab Automation Robots |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Novarad | Provo, UT | Imaging Software and Technology |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| PlaSalus | , | Amateurish looking |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Recensa Therapeutics | , | Only employee gone 2018 |
| HebeCell | Natick, MA | Cell Therapies |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| , | Acquired by StarFish Medical, Nov 2024 | |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Imeka | Sherbrooke, QC | Neuroimaging |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Lorantis | , | Merged with Celldex 2005 |
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Cala Health | San Mateo, CA | Neurological Device |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| SolaranRx | , | Website taken over |
| , | Shut down Mar 2026 | |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| , | Acquired by Vaxanix, May 2024 | |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| BioSpherex | , | Renamed Metabiomics |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Applied Therapeutics | New York, NY | Small Molecules |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Olymvax | Chengdu, China | Vaccines |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| Evinco Therapeutics | , Australia | NK cell-derived extracellular vesicles for Alzheimer's and neuroimmune diseases |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| VictoGen | Simi Valley, CA | Analytical, Formulation Development, Regulatory |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Nostrum Laboratories | Kansas City, MO | Generics |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| Bionode | , | Shut down Mar 2024 |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| , | Linkedin gone Jul 2026; Website down Jun 2026 - Jul 2026; Cyrus Biotechnology spinout | |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| Clear Image Technology | , | Now CIT Ortho |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| JK Biopharma Solutions | , | Founder gone |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Ho’ola Therapeutics | , | |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| SERB Pharmaceuticals | West Conshohocken, PA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| |
Abingdon, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Qynapse | Boston, MA | Imaging Analysis |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| Primera Biosystems | , | Now PrimeraDx |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Veracyte | South SF, CA | Cytology Diagnostics |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| , | Website down May 2025 - Dec 2025 | |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Allometra | , | Gone |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| VLST Corp | , | Wound Down, Jun 2013 |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| CareDx | Brisbane, CA | Diagnostics |
| |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| EcoSurg | , | Shut Down May 2017 |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Alsinova | Boulogne-Billancourt, France | Clinical & Regulatory Consulting |
| Taxolog | , | Website gone, Nov 2015 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| , | Website down Aug 2025 - Jan 2026 | |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| , | No news 2018 - Sep 2025 | |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Altus Biologics | , | Vertex Subsidiary |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| Nascent Biologics | , | Changed to Nascent Biotech |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| , | Acquired by Biogen, Nov 2025, $85M; fka Alcyone Lifesciences | |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| Synergistix | Sunrise, FL | CRM software |
| Anergis | , | Liquidating, Jan 2021 |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Genova Clinical Research | , | Gone, 2014 |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| , | Merged with DefiniGEN to become pixl.bio | |
| , | Renamed First Atom Therapeutics | |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Prescos | , | Shut down Feb 2014 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| Cytera CellWorks | , | Renamed Mytos |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| Quest Clinical Research | , | Now part of eStudysite |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Shionogi | Florham Park, NJ | Small Molecules |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| Comac Medical | Sofia, Bulgaria | European CRO |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| , | Renamed PsiThera, Dec 2025 | |
| Tempered Biosciences | , | Absurd website has to be gone |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| MediQuest Therapeutics | , | Gone? |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| Avrygen | , | Website Gone, execs gone |
| ADispell | , | Website gone Apr 2018 |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| GenEndeavor | Hayward, CA | Diagnostics |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| Geneffects | , | Shut down Feb 2020 |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Katalyst Healthcare and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Nova Biomedical | Norwood, MA | Lab instruments |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| Accelrys | , | Bought by Dassault, 2014 |
| Fonar | Melville, NY | Upright MRI |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Velcura Therapeutics | , | Website Gone |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| , | Renamed Verge Labs, May 2026 | |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| EmerVax | , | Renamed Circurna |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Empatica | Cambridge, MA | Seizure Detection |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Odyssey Thera | , | Shut down 2014 |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| Hansa Medical | , | Renamed Hansa Biopharma |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| Bioptimus | Paris, France | AI Drug Discovery |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| ProPharma Group | Raleigh, NC | Consulting |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Celavie Biosciences | , | Shut down Mar 2024 |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| Accugent Laboratories | , | Website gone Sep 2017 |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| PDL BioPharma | , | Shut down early 2021 |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Alaeras | , | Dissolved Jan 2014 |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| Getinge | Rastatt, Germany | Medical Technology |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| Premier Biomedical | , | Pivoted out of life science |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| BHR Pharma | , | Subsidiary of Besins |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Mediatech | , | Now Cellgro |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| GNQ Insilico | Pleasanton, CA | In Silico Genomics |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Furong Biotech | , | |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| , | Liquidated 2024 | |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| , | Website down Aug 2025 - Jan 2026 | |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| Metrochem | Hyderabad , India | APIs |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Ansata Therapeutics | , | Out of business 2007 |
| Cordis | Miami Lakes, FL | Medical Devices |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| , | Renamed Entirety Biomedical | |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Autonomic Technologies | , | IP acquired by Unity HA |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| Cambria Biosciences | , | Gone Feb 2008 |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Sanarus | , | Acquired by Hologic, 2020 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| GlycoEra | Newton, MA | Custom Glycan Platform |
| , | Website taken over May 2026 - Jun 2026 | |
| Aimmune Therapeutics | , | |
| , | Acquired by Maverix Medical, Dec 2023 | |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| Ganymede | Palo Alto, CA | Lab Automation |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Catamaran Bio | , | Winding down Jan 2024 |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| TAI Diagnostics | , | Gone |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| Michrom | , | Bought by Bruker, Feb 2011 |
| Sanofi | North York, ON | Biologics, Vaccines |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| Terumo Medical | Elkton, MD | Medical Devices |
| WideCELLS | , | Shut down Nov 2019 |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| , | Website down Dec 2025 - Jun 2026 | |
| Ciphergen | , | Now Vermillion |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| , | ||
| , | Insolvent, sold off Jan 2024 | |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| Integer | Alden, NY | Medical & Surgical Devices |
| Celsis | , | Now AAIPharma |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| MyoSyntax | , | Gone 2021 |
| , | Liquidating, Sep 2025 | |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| IQVIA | Durham, NC | Clinical Research |
| Excelsyn | , | Bought by AMRI |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| , | ||
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| NeoRx | , | Changed name to Poniard, May 2006 |
| hC Bioscience | , | Shut down Mar 2025 |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| , | Founder left Jul 2025, still on website Jul 2026; LI gone Jul 2026 | |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| FocalTherics | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Grannus Biosciences | , | Gone |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| R/D Clinical Research | , | Website Gone |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Evozyne | Chicago, IL | Protein Design Platform |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| NantHealth | El Segundo, CA | Diagnostics |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| , | Acquired by InformedDNA, Mar 2025 | |
| LianBio | , | Winding down Feb 2024, came back Jul 2026 as LianMedical |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| Magnendo | Newton, MA | Neurovascular Access with Robotic Navigation |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Delpharm | Milan, Italy | Contract Manufacturing |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| Simondr | , | Website gone, President has new job |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Nasseo | , | Gone |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| , | Renamed Stelexis BioSciences | |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Sysmex | Tokyo, Japan | Diagnostics |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| , | Acquired by eurofins, Jun 2019 | |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| Inexia | , | Acquired by Centessa |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Pharmaron | Hertfordshire , UK | R&D Services |
| , | Website taken over May 2026 | |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Convergen LifeSciences | , | Renamed Genprex |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Orion Genomics | St. Louis, MO | Biomarkers |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| ViaCord | , | Part of PerkinElmer |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| Erba MDX | , | Website gone Aug 2019 |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Antara Biosciences | , | Bankrupt 2007 |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| Gen Plus | Munich, Germany | Formulation |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Abgenix | , | Bought by Amgen 2006 |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Rubicon Research | Thane , India | Generics |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| Abiologics | Cambridge, MA | Synteins |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| Provecs Medical | , | Gone Nov 2019 |
| DecImmune Therapeutics | , | Gone 2017 |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Biotel | , | Acquired by CardioNet, 2010 |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| , | Acquired by Artis Jun 2026 | |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| NovoLipid | , | Website Gone |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| Quartzy | Hayward, CA | Lab Management Software |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| Gene Techno Science | , | Renamed Kidswell Bio |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Aimsn Medical | Shanghai, China | Devices, Implants, First Aid |
| Ebewe Pharma | , | Now Sandoz |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| AstraZeneca | Boston, MA | Biologics |
| Redpoint Bio | , | Inactive |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| VitalMedix | , | Out of Money 2010 |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| Orange Biotech | Hong Kong, China | Microfluidic nucleic acid detection system empowered with CRISPR |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| Sortis Pharma | Hyderabad, India | Contract Services |
| NKMax America | , | Renamed NKGEN Biotech |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| American Stem Cell | , | Changed name to Targazyme |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| MJ Biopharma | Mumbai, India | Generics |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| , | Website taken over Feb 2026 | |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| Proteonomix | , | Shell Company |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| MicroPort | Saluggia, Italy | Medical Devices |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| SERB Pharmaceuticals | Dubai, UAE | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| GTX Medical | , | Renamed ONWARD |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| VitamFero | , | Website gone Aug 2018 |
| McGee Pharma | , | Merged with Pharmalex |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Sepracor | , | Now Sunovion |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| , | Shut down Jul 2025 | |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Cogentis Therapeutics | , | No news 2017-2023 |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| Celvive | , | No news from 2012-2020 |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| CanTx | , | Website gone, Feb 2015 |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Repligen | Waltham, MA | Protein Manufacturing Equipment |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| KynderMed | , | Renamed Prena |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| TME Pharma | Berlin, Germany | L-aptamers |
| |
Verona, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| Elektrofi | Boston, MA | Biologics Formulation |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Aptamer Group | York, UK | Aptamer selection and development services |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Gentegra | , | Part of IntegenX |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| , | Shut down Jul 2025 | |
| JAJ International | , | Website not working, redirecting strangely |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Axikin Pharmaceuticals | , | Closed per Google |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Spear Bio | Woburn, MA | Immunoassays |
| Altasciences | Montréal, QC | Contract Research |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| Ackley Hartnett | Langhorne, PA | Tablet Machines |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Jerini | , | Acquired by Shire, 2008 |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Boragen | , | Renamed Reactive Biosciences |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| , | Acquired by Instem, Jul 2025 | |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| Rubix Device | , | Website gone, Aug 2017 |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Agilent | Longmont, CO | High-Throughput Screening Equipment, Imaging instruments |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Sonexa Therapeutics | , | Closed 2013 |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| preclinics | Eystrup, Germany | Contract Research |
| GSL Biotech | , | Acquired by Dotmatics |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| AnaBioTec | , | Now Anacura |
| Network Bio | Palo Alto, CA | Disease-specific AI models from human biological data |
| BINEX | Busan, Korea | Biologics CDMO |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| Protein Metrics | Boston, MA | Protein characterization software |
| Qlucore | Lund, Sweden | Visualization Software |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| GenSure | Shijiazhuang, China | Diagnostics |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Satoris | , | Bought by Rules-Based Medicine |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Hologic | Beijing, China | Diagnostic, Imaging |
| AIBioTech | , | Assets auction, Aug 2017 |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| |
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Miami Cardiovascular Innovations | , | Gone Sep 2009 |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Light Sciences Oncology | , | Shut down late 2020 |
| PluriCell | , | Renamed LizarBio |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Tychan | , | Liquidated early 2022 |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| Brilliant Research | , | Website gone Dec 2018 |
| Sanofi | Paris, France | Small Molecules |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Protalex | , | Failed 2018, shell |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Madison Vaccines | , | Website gone Dec 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| CG Therapeutics | , | Dissolved Jul 2013 |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| Avexxin | , | Rebranded as Coegin Pharma |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Aranscia | Houston, TX | Diagnostic Software |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| Optherion | , | Sold Assets, Still Exists |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| Brighton Biotech | , | Only employee is an accountant |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| , | Renamed Mobia Medical, Feb 2026 | |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| Lavipharm | East Windsor, NJ | Small molecules |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Covenant Therapeutics | , | Gone |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Parsolex | , | |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Meristem Therapeutics | , | Defunct |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Spirox | , | Bought by Stryker, Jul 2017 |
| Verenium | , | Bought by BASF, Dec 2013 |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Viwit | Shanghai, China | APIs, Formulation |
| FluoroPharma | , | Shell Company |
| Yicura | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| Omnia Biologics | , | Website gone Sep 2017 |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| NIOX | Morrisville, NC | Asthma management device |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Novalar | , | Licensing agreement, essentially gone |
| AssureRx | , | Renamed Assurex Health |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Urogenix | , | Acquired by Astellas |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| EMS | Hortolândia, Brazil | Small Molecules |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Lavipharm | Peania, Greece | Small molecules |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| Ventaleon | , | Shut down 2020 |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| , | Acquired by Merck, Oct 2025, $10B | |
| Arzeda | Seattle, WA | Computation protein design |
| XaTek | , | No news 2021 - Feb 2025 |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Gentian USA | Moss, Norway | IVD Products |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Veramed | London, UK | Biostatistics and programming services |
| Zila | , | Bought by Tolmar, Jul 2009 |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Getinge | Getinge, Sweden | Medical Technology |
| United Neuroscience | , | Renamed Vaxxinity |
| Alcon | Houston, TX | Eye-Care Products |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| Singular Genomics | San Diego, CA | Genomics |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| , | Website down Aug 2025 - Jan 2026 | |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| , | Website down Jun 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Pharmaron | Beijing, China | R&D Services |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Compass Biotech | , | Defunct |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| Nizyme | , | Gone Jul 2015 |
| Solace Pharmaceuticals | , | Out of business 2011 |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Novosis | , | Acquired by Acino, 2006 |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Excalipoint Therapeutics | Shanghai, China | Cell Therapy, Antibodies |
| Automata | London, UK | Lab workflow automation platform |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| Noucor Health | Barcelona, Spain | Small Molecules |
| , | Acquired by Epitype, Oct 2025 | |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| Dopl Technologies | Seattle, WA | Imaging |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| Medipacs | , | Shut down Jul 2024 |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Progenika | , | Bought by Grifols |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Delpharm | Tours , France | Contract Manufacturing |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Vernacare | Blackwood, UK | Surgical Devices |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| DiAthegen | , | Website Gone Oct 2015 |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Abpro | Lexington, MA | Antibodies |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| , | Acquired by Azenta, Feb 2023 | |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Triangle Insights Group | Durham, NC | Consulting |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Avomeen | , | Acquired by Element, Mar 2021 |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| Affitech | , | Gone |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| vTv Therapeutics | High Point, NC | Small molecules |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Piramal | Grangemouth, UK | CDMO |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Otsuka | Rockville, MD | Small Molecules |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| Alan Laboratories | , | Website gone, Jan 2019 |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Nabla Bio | Cambridge, MA | Antibody Design |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Cenix Biosciences | , | Website gone Jul 2015 |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Zecui Biotech | , | Cell Therapy |
| Semaphore Solutions | Victoria, BC | Lab Software |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| CORONIS | Athens, Greece | Clinical Studies |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| , | Acquired by Novartis, Oct 2025, $1.4B; Merged with Talaris Therapeutics, Oct 2023 | |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| , | Shell used for reverse merger by Serapha Bio, Jun 2026 | |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Nura Bio | South SF, CA | Small Molecule |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Heart Tronics | , | Effectively defunct after scandal |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| Aureon Biosciences | , | Insolvency Proceedings |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| , | Acquired by Xoma, Nov 2025 | |
| Cellevolve Bio | , | Shut down Aug 2023 |
| Intellimedix | , | Company founder/employee all moved on |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| ProteinLinks | , | Seem gone |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| , | Renamed Grey Matters Health, Apr 2026 | |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| , | ||
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| , | ||
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Northern Lipids | , | Renamed Transferra |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| , | Website down Feb 2026 - Jul 2026 | |
| DxTerity | Torrance, CA | Genomic Testing |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Inflammix | , | Renamed AnchorBio Solutions |
| CPI Global | , | Website gone Jun 2020 |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Institute for Drug Discovery | , | Gone |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Accumed Systems | , | Dated website, cant find any employees |
| DDL | Irvine, CA | Device Testing |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Vasade Biosciences | , | Gone |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| , | Website down Mar 2026 - Aug 2026 | |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| iThemba Pharmaceuticals | , | No information |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| Huons | Seongnam, Korea | Small Molecules |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| GenomeKey | Bristol, UK | IVD Device |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Acrongenomics | , | No info since 2013, seems gone |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| , | Acquired by MasterControl, Mar 2025 | |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| Soluble Systems | , | Renamed Solsys Medical |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| , | Renamed Indero | |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Gene Sciences | , | Shut Down Jul 2019 |
| T-Ray Science | , | Renamed Verisante |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Acculysis | , | Website gone, sole employee with Agilent now |
| Cebix | , | Shut down, Feb 2015 |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| , | Inactive 2025 | |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| PhotoThera | , | Ceased operations Dec 2012 |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| NIOX | Uppsala, Sweden | Asthma management device |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| Azopharma | , | Bankrupt, Apr 2010 |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Genitope | , | Wound Down |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| Sytera | , | Merged with Sirion Aug 2006 |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| Veeva Systems | Radnor, PA | Life Science Software |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| |
Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| |
Redmond, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| Correlogic | , | Assets bought by Vermillion 2011 |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| RhinoCyte | , | Website moved to a marketing agency domain |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| Pharmexon | Prague, Czech Republic | Consulting |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| , | ||
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| NKT Therapeutics | , | Shut down May 2021 |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Streamline Scientific | Austin, TX | Molecular Technologies |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Leucid Bio | London, UK | Cell Therapy |
| Vivid Genomics | , | Shut down Sep 2023 |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Viragen | , | Liquidated Oct 2007 |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| Eisai | Nutley , NJ | Small Molecules |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Pangea Pharmaceuticals | Fort Lauderdale, FL | Generics, B2 |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Apaxis Medical | , | Gone 2019 |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Apollo Scientific | Manchester, UK | Research Products |
| , | one page website ©2020 in Jul 2026 | |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Biolab | São Paulo, Brazil | Small Molecules |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| Intact Genomics | St. Louis, MO | PCR kits |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| Psomagen | Rockville, MD | Genetic Sequencing |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Active Pass Pharmaceuticals | , | Gone |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| NewHeart Devices | , | Gone |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Abpro | Burlington, MA | Antibodies |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| , | Part of Genesis | |
| Amstem | , | SEC problems |
| BioMendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| , | Shut down Jan 2025 | |
| |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| AB Sciex | , | Renamed Sciex |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| Avaxia Biologics | , | IP acquired by Circle33 |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| |
Seattle, WA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| Molsid | Lyon, France | Fluorogenic Probes |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| Soin Neuroscience | , | Seems like one guy, sold tech Jul 2026 |
| Iproteos | , | Products now with Accure Therapeutics |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| , | Acquired by Affluent Medical, Feb 2026 | |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| SOLADIS | , | Acquired by Efor, 2021 |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| , | Shut down Aug 2025 | |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| , | Website taken over, Nov 2025 | |
| , | Winding down, Dec 2025 | |
| Ipsen | Sumter, SC | Biologics |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| Molecular Loop | Woburn, MA | NGS Technology |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Lab Owl | , | Part of Inflexion Point |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| , | Subsumed into GSK, Jun 2026 | |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| Meabco | , | |
| , | Website down Oct 2025 - Feb 2026 | |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Eccogene | Shanghai, China | Small Molecules |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Roslin Cells | , | Renamed RoslinCT |
| Xencor | Pasadena, CA | Antibody Discovery |
| Scintillant Bioscience | , | Gone May 2025 |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| CanCure | , | No news 2017 - 2024 |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| BA Sciences | Morrisville, NC | Analytical Services |
| Hana Biosciences | , | Now Talon Therapeutics |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Renamed BreezeBio, Feb 2026 | |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| Stada | Bad Vilbel, Germany | Generics |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Fujifilm Biotechnologies | Thousand Oaks, CA | Biologics Development & Manufacturing |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| Sojournix | , | Shut down Jun 2021 |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| MSD | Leopardstown, Ireland | Small Molecules |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| NNS Clinical Research | , | Gone |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| , | Website down Jun 2025 - Dec 2025 | |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| CombinatoRx | , | Now Zalicus |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| , | Acquired by Again, Aug 2026 | |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| Opis Research | Desio, Italy | Clinical Research |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| Endo Tools Therapeutics | Gosselies, Belgium | Triangulation platform for tissue piercing |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| , | Website down Jan 2026 - May 2026 | |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| OneSource Specialty Pharma | Bengaluru , India | CDMO |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| ApcinteX | , | Centessa Company |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Parabase Genomics | , | Presumed gone |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| SynapDx | , | Shut down, Mar 2017 |
| Immerge BioTherapeutics | , | Founded 2000 |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Celerion | Belfast, UK | Clinical Research |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Photonion | Schwerin, Germany | Analytical Equipment |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Salvat | Barcelona, Spain | Small Molecules |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| Sierra Surgical | , | Shut down Feb 2019 |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Silere Medical Technology | , | Shut down Dec 2013 |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| Claritas Genomics | , | Closed Jan 2018 |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Audubon Bioscience | Houston, TX | Biospecimens |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| Tecomet | Warsaw, IN | Finishing, CNC Machining, Additive Manufacturing, Grinding |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Denk Pharma | Munich, Germany | Generics |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Neuronax | , | Renamed Axoltis Pharma |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| Tanai Therapeutics | , | Obesity Treatment |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Therabest | Seoul, Korea | iPSC |
| Tigris Pharmaceuticals | , | Now Kirax |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| Glyphic Biotechnologies | Berkeley, CA | Protein Sequencing Platform |
| Alcon | Fort Worth, TX | Eye-Care Products |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| ImmuRx | , | Gone, not sure what happened |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Excelimmune | , | Closed Jul 2016 |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| EVerZom | Paris, France | Exosome Therapeutics |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| NeuroSearch | , | Wound down 2012 |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Roche | Basel, Switzerland | Small Molecules |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| AN2 Therapeutics | Menlo Park, CA | Boron-based medicines targeting infectious diseases |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Sharp | Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Scynexis | Jersey City, NJ | Small Molecules |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| Getinge | Solna, Sweden | Medical Technology |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| Vista Scientific | , | Shut down Dec 2015 |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| Quanticate | Bangalore, India | Clinical Research |
| Genecure | , | Shut down Sep 2021 |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| , | Shutdown Oct 2025 | |
| GenSensor | Nantes, France | Process Analytical Technology |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Zuma Biosciences | , | Company Gone |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| , | Website taken over, Feb 2026 | |
| Wheaton | , | Renamed DWK Life Sciences |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Phenomyx | , | Gone Jun 2019 |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| , | Website down Jun 2025 - Dec 2025 | |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Partek | , | Acquired by Illumina, May 2024 |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| QInstruments | Jena, Germany | Lab Instruments |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| Roche | Basel, Switzerland | Diagnostics |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| mAbRx | , | Gone |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| Genex Pharma | Mumbai , India | Generics |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| , | Website down Dec 2025 - Apr 2026 | |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Geron | Foster City, CA | Small Molecule |
| , | Gone Aug 2026; Medigene spinout | |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| Mott | Farmington, CT | HPLC system components, Filtration |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| Tecomet | Manchester, NH | Case Design, CNC Machining, Injection Molding, Metal Forming, Vacuum Forming |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| Denizen Biologics | , | Shut down Mar 2023 |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| K2M | , | Acquired by Stryker, Nov 2018 |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| R2M Pharma | South SF, CA | Drug Development Services |
| Core Prognostex | , | Seems inactive |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| Eyetech | , | Website Gone 6-16-12 |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| MicroPort | Shanghai, China | Medical Devices |
| Oticon | Smørum, Denmark | Hearing Aids |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Stago | Marseille, France | Diagnostics |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| bioTHER | , | Gone |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Proteorex | , | Gone Nov 2017 |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Santen | Osaka, Japan | Ophthalmics |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| , | Website down May 2025 - Dec 2025 | |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Allux Medical | , | Shut down, Feb 2009 |
| Trophea | , | Liquidated, Dec 2019 |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| MikrobEX | , | Renamed Rebiotix |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Tecomet | Memphis, TN | Bone In-Growth Coating |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| , | Shut down Sep 2025; fka GenoFAB | |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| iKaryos Diagnostics | , | Gone |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| MSN Labs | Hyderabad, India | Generics |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| GeneVivo | , | Unknown Fate |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Grunenthal | Origgio, Italy | Small molecules |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| MicroStem | , | Gone Jun 2017 |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Axplora | Chennai, India | API manufacturing |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| VALOS | Genova, Italy | Clinical Statistics |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| RSSL | Reading, UK | Analytical Services |
| , | Website down Nov 2025 - Apr 2026 | |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| Z-Factor | , | Centessa Company |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| NeuroVia | , | Shut down 2019 |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| Theranostech | , | Renamed Sandia Biotech |
| , | Renamed Carvolix, Feb 2026 | |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| Ossis | , | 3D-printed orthopedic implants |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| ProPharma Group | London, UK | Consulting |
| Synthace | London, UK | Development Software |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| , | Acquired by Healx, Sep 2025 | |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| XRlabs | Albacete, Spain | Surgical Intelligence, Visualization |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Amorsus | , | Website Gone 8-30-13 |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Ansaris | , | Gone |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| , | Renamed Ribonexus, Nov 2021 | |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| DDi | Monmouth Junction, NJ | Clinical Software |
| Amplyus | , | Renamed miniPCR |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| XW Laboratories | , | Renamed XWPharma |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Aegea Biotechnologies | , | |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Dynatherm Medical | , | Shut down 2012 or later |
| Coordination Therapeutics | , | Not Active |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| In Cell Art | , | Website taken over Feb 2025 |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| SK Biotek | , | part of SK pharmteco |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| , | Website down Jan 2026 - May 2026 | |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| , | Website down Nov 2025 - Apr 2026 | |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| IDM Pharma | , | Acquired by Takeda |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Ceronco Biosciences | , | Gone 2015? |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| ReproSource | Marlborough, MA | Fertility Testing |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| VIVUS | Campbell, CA | Small Molecules |
| NeuroPharm | , | Liquidated 2010 |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Reserva | , | Renamed NeurMedix, 2016 |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| myoscience | , | Renamed iovera |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| , | Acquired by Ligthouse Lab Services | |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Yung Shin Pharm | Taichung, Taiwan | Small Molecules, Generics |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| Veeva Systems | Toronto, ON | Life Science Software |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| Life Stem Genetics | , | Basically gone |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| , | Now PamDx, May 2026 | |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| , | Website down Nov 2025 - Apr 2026 | |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| Arbovax | , | Gone |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| Getinge | Wayne, NJ | Medical Technology |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| Abbott | Singapore, Singapore | Diagnostics |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| CereSpir | , | No news 2020 - Nov 2024 |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Bioventus | Durham, NC | Orthobiologics |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| Celerion | Lincoln, NE | Clinical Research |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| IDRx | , | Acquired by GSK, Feb 2025 |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Advanced Peptides | , | No business filings since 2011 |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| MediWound | Yavne, Israel | Wound & Burn Care |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Ergomed | Krakow, Poland | Clinical Research |
| Angiomics | , | Product being sold by another company |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| DxNow | , | Renamed ZyMot fertility |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| , | Website down Jul 2025 - Dec 2025 | |
| , | Acquired by Takara Bio, Jan 2025 | |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| MindWalk | Victoria, BC | Custom Antibodies |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Obexia | , | Gone |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| Oligasis | , | Changed named to Kodiak Sciences |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| superDimension | , | Acquired by Covidien May 2012 |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Accellacare | Bristol, TN | Clinical Research |
| Figure8 Surgical | , | Surrendered business in CA |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| , | Acquired by Principal Technologies, Dec 2024 | |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Catalent | Winchester, KY | Contract Manufacturing |
| Integer | Plano, TX | Medical & Surgical Devices |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Azad Pharma | Montreal, QC | APIs, generics |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Blansett Pharmacal | , | Gone Jan 2019 |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| , | Shut down Jan 2025 | |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Ikotech | , | Closed Dec 2015 |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| SERB Pharmaceuticals | Rosedale, Australia | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Peplin | , | Acquired by Leo Pharma 2009 |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| White Biotech Solutions | , | Shut Down 2019 |
| SERB Pharmaceuticals | Ceredigion, UK | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| LFB | Paris, France | Plasma derived drug products |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| M3 Wake Research | Encino, CA | Clinical Research |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Groton Biosystems | , | Gone before Jun 2015 |
| Axbio | Santa Clara, CA | Biochips |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| Transave | , | Merged with Insmed Dec 2010 |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Innomab | , | Gone 2017 |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| , | Website down Dec 2025 - Apr 2026 | |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Kelliop | Newark, CA | Diagnostic Reader |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Sanofi | Frankfurt, Germany | Small Molecules |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Aves Labs | , | Now part of Antibodies Inc |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Cuda Pharmaceuticals | , | Presumed gone |
| HiMedia Laboratories | Kennett Square, PA | Microbiology Products |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| Niveus Medical | , | Closed Dec 2017 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| Obenomics | , | No website Apr 2014 |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Human Genome Sciences | , | Bought by GSK |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| , | Bankrupt, ceased operations Mar 2026 | |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| IQVIA | San Diego, CA | Clinical Research |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Kvvit Pharmaceutical | , | |
| Biotagenics | , | Renamed MedBiome |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| NeurOptics | Irvine, CA | Pupillometry |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| E3X Bio | , | Shut Down Mar 2019 |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| Veeva Systems | Shanghai, China | Life Science Software |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Rezolute | Redwood City, CA | Biologics |
| Attogene | Austin, TX | Rapid Diagnostics |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Tangent Medical Systems | , | Closed |
| , | Bankrupt Jun 2025 | |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Ambu | Ballerup, Denmark | Medical Devices |
| , | Website down Jan 2026 - Mar 2026 | |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| Iktos | Paris, France | AI for New Drug Design |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| VasoRx | San Diego, CA | RNA delivery |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| MiniMed | Northridge, CA | Diabetes Management |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| On-Q-Ity | , | Closed 2013 |
| , | Website down Apr 2026, seems bankrupt | |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| Pathfinder Cell Therapy | , | Gone 2016 |
| , | Website down Sep 2025 - Dec 2025 | |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Grunenthal | Quito, Ecuador | Small molecules |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Microsure | Son, Netherlands | Surgical Robots |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Domainex | Essex, UK | Drug Discovery Services |
| Defyrus | , | Website gone Nov 2017 |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| Lotte Biologics | East Syracuse, NY | Biologics CDMO |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Saniona | Glostrup, Denmark | Small Molecules |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| , | CEO left 2020, still on website Dec 2025 | |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| Salvat | Miami, FL | Small Molecules |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| Invenio Imaging | San Jose, CA | Histology, Cavity Sampling |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| PACT Pharma | , | Shut down Sep 2023 |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| Sage Science | Beverly, MA | DNA Fractionation |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| Rhythm Health | , | Renamed Motus Therapeutics |
| MeiraGTx | London, UK | Gene Therapy |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Hutchmed | Hong Kong, China | Oral drugs |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| Frenova | Waltham, MA | Renal clinical research |
| BioDot | Irvine, CA | Equipment |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| Noble | Orlando, FL | Auto-injector Trainers |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| NTRC | , | Now Oncolines |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Central Pharma | Bedford, UK | Filling, Packaging |
| OncoCell MDx | , | Renamed Immunis.AI |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| Ossur | Irvine, CA | Orthopedic Devices |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| , | Acquired by Scantox, Sep 2024 | |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| VistaMed | , | |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| , | No news 2021 - Jan 2026 | |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| Molecular Logix | , | Gone, Dec 2018 |
| BIOMODEX | , | Acquired by Mentice |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| , | Acquired by BMS, Dec 2025, $1.5B | |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Alkem Labs | Mumbai, India | Generics |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| , | ||
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Bastion Therapeutics | , | Shut down |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| , | ||
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| ABS Bio | New Castle, DE | Custom Bioreagents |
| Revvity | Boston, MA | Diagnostics, Services |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| 3D Biomatrix | , | Closed down |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Remora Therapeutics | , | Shut down 2021 |
| Genetron Health | Beijing, China | Diagnostics |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| Cardeas Pharma | , | Gone, 2017 |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Carticept Medical | , | Dissolved Feb 2020 |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Kalypsys | , | Gone |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| , | Renamed Algernon Health, Oct 2025 | |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| Piramal | Pithampur, India | CDMO |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| , | Acquired by Sensei Biotherapeutics, Feb 2026, took name Jun 2026 | |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Cognis Corp | , | Acquired by BASF 2010 |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Proteotech | , | Website gone Jul 2015 |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Biocious Life Sciences | , | Now Agilent |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Zyomyx | , | Closed as of 2014 |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| Selah Genomics | , | Seems gone after being sold back to founder |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| CatSci | Cardiff, UK | Contract Research |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Tapestry Pharmaceuticals | , | Gone |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| Biowarn | , | Gone |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Ingenetix | Wien, Austria | PCR Products |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| , | Website down Oct 2025 - Feb 2026 | |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| , | Acquired by Kite, Aug 2025 | |
| , | Acquired by Repligen, Sep 2021, $150M | |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| Ginkgo Bioworks | Boston, MA | Autonomous Labs |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Calypte Biomedical | , | Gone |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| Mithridion | , | Website Gone, Company appears to be as well |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Sygene Technologies | , | Website gone Nov 2018 |
| , | Acquired by R-Biopharm, Jun 2022 | |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| Griffin Laboratories | , | Acquired by Atos Medical |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| Velomedix | , | Shut down 2014 |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| Heritage Pharmaceuticals | , | Part of Emcure |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Statera Therapeutics | , | Shut down Jan 2022 |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| BrainCells | , | Website gone Feb 2014 |
| Anfiro | , | Shut down Dec 2019 |
| , | Renamed Racura Oncology, Dec 2025 | |
| Sanovel | Istanbul, Turkey | Generics |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| Elanex Pharmaceuticals | , | Gone |
| Indomo | Virtual, US | Acne Treatment |
| Esoterix | , | Bought by LabCorp, May 2005 |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| DMD Therapeutics | , | Gone Nov 2018 |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Inovio Biomedical | , | Seems gone |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Solventum | Eagan, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| , | Renamed Trace Biosciences | |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Cell Biosciences | , | Now ProteinSimple |
| EVA Pharma | Giza, Egypt | Branded Generics |
| , | Website down Nov 2025 - Dec 2025 | |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| Biotechnical Services | , | Shut down Apr 2019 |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| , | Main person has four other jobs, Dec 2025 | |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| , | Now part of Sanisure, Jun 2026 | |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| , | ||
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| , | Website down May 2025 - Dec 2025 | |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Molsoft | San Diego, CA | Drug Design Software |
| Streamline Scientific | Birmingham, AL | Molecular Technologies |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Palmaz Scientific | , | Bankrupt, 2016 |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| , | Renamed Cellixx, May 2026 | |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| , | Renamed Flourish Biologics, Jul 2026 | |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Zevra Therapeutics | Boston, MA | Modifications of Existing Drugs |
| TRIA Bioscience | , | Shut down Aug 2021 |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Altasciences | Harleysville, PA | Contract Research |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Calixar | Lyon, France | Membrane Proteins |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Labopharm | , | Bought by Paladin 2011 |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Thermo Fisher | Bend, OR | CDMO |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| America Stem Cell | , | Changed name to Targazyme |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| InnoCare | Nanjing, China | Cancer Treatments |
| Clina Research | , | Website gone Jul 2023 |
| TheoremDx | , | Bankrupt Feb 2020 |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| NeuroproteXeon | , | Gone 2021 |
| Perceptive | Nottingham, UK | Medical Imaging |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| Valitor | Berkeley, CA | Protein therapeutics |
| MabSpace Biosciences | , | Renamed Transcenta |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| Profluent | Emeryville, CA | AI Protein Creation |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Formation Biologics | , | Rebranded as Forbius |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| iCareDx | , | Renamed AcuamarkDx |
| Sciele Pharma | , | Bought by Shionogi |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Doloromics | , | Shut down Mar 2025 |
| SERB Pharmaceuticals | Luxembourg, Luxembourg | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| Synfini | Menlo Park, CA | AI Drug Design |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Stago | Maastricht, Netherlands | Diagnostics |
| , | Acquired by Avania, Oct 2024 | |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Tactic Pharma | , | Website gone, Apr 2018 |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| , | Website down Jul 2025 - Nov 2025 | |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| , | Acquired by Teva, Jun 2026, $700M | |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| Apieron | , | Shut down, May 2010 |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| Xegen | Gemenos, France | NGS Data Analysis |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Faze Medicines | , | Shutting down Nov 2022 |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| CellCarta | Montréal, QC | Clinical Research |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| ConquerX | , | Dissolved Jun 2021 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| , | Renamed FocalTherics, May 2026 | |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Cytiva | Burnaby, BC | Cell Culture Products |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| BiomerTechnology | , | Ancient website, never registered in CA |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Warnex | , | Merged into DIAGNOS Inc |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| BioRelix | , | Restructured. Unknown Status. |
| Totient | , | Acquired by Absci, Jul 2021 |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| medac pharma production | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| BGI | Shenzhen, China | Genetic Testing |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| , | Website down Jun 2025 - Dec 2025 | |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| , | Website down Mar 2026 - Aug 2026 | |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Strike Bio | , | Assets auction, Aug 2017 |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| , | Renamed Envue, Feb 2026 | |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| , | Website down Feb 2026 - Jul 2026 | |
| Calcionics | , | Shut down 2010 |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Alderon Biosciences | , | Presumed gone |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| , | Now Hilo, Jul 2026 | |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| Qualiber | , | Presumed inactive, website gone |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| Cholestech | , | Now Alere |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| Cell Therapy Ltd | , | Renamed Celixir |
| Bionsight | Seoul, Korea | Database For Research |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Dropshot Therapeutics | , | |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Cyto360 | , | Website gone Aug 2018 |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| XtalPi | Cambridge, MA | AI Drug Design |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| Chroma Medicine | , | |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| Fairway Medical Technologies | , | Website gone |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Activated Cell Therapy | , | Changed name to Dendreon |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Eternans | , | Shut down Jul 2022 |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| Meta-Iq | , | Website gone Jun 2020 |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Ergomed | Madrid, Spain | Clinical Research |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Alimentiv | San Diego, CA | Clinical Services |
| Michigan Clinical Research Institute | , | |
| , | Website down Feb 2026 - Aug 2026 | |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| , | Bankruptcy Oct 2024 | |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Traversa Therapeutics | , | Bankrupt |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| Collgard Biopharmaceuticals | , | Gone |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| , | Website down Sep 2025 - Feb 2026 | |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Kura Oncology | San Diego, CA | Small Molecules |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Omnitura | , | Website gone Jan 2022 |
| Chanelle Pharma | London, UK | Generics |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| Heraeus Medical | Yardley, PA | Medical Devices |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| , | Website down Oct 2025 - Feb 2026 | |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Itero Biopharmaceuticals | , | Website Gone |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Getinge | Plewiska, Poland | Medical Technology |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Medivector | , | Gone late 2018 |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Zai Lab | Cambridge, MA | Small Molecules |
| OFD Biopharma | Albany, OR | Lyophilization |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Ottobock | Vienna, Austria | Prosthetics |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Orion | Espoo, Finland | Drugs, Diagnostics, Veterinary medicine, etc. |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| , | Renamed Arpelos Biosciences | |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| Epic Pharma | Laurelton, NY | Generics |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| , | Dissolved, Apr 2024 | |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| Pangaea Pharmaceuticals | , | Became Zycos |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| Imstem Biotechnology | , | Website gone May 2021 |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Spring Discovery | , | Renamed Spring Science |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| , | Renamed Hermes Biosciences | |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Abselion | Cambridge, UK | Biologics Quantification |
| Alxerion Biotech | , | Gone May 2021 |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Accellacare | Raleigh, NC | Clinical Research |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Cerimon Pharmaceuticals | , | Gone |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| , | Website down Jan 2026 - May 2026 | |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Chrysalis | Morrisville, NC | GMP Space |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Genmab | Plainsboro, NJ | Biologics |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Adaptix | Oxford, UK | Medical imaging |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Neugenesis | , | Bought by Intrexon, 2011 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| Corza Medical | Somerset, UK | Surgical Devices |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| Pfizer | Puurs, Belgium | Packaging |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| Axplora | Mourenx, France | API manufacturing |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Aspira Labs | , | Renamed Aspira Women's Health |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| SilaGene | , | Gone |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| Idience | San Francisco, CA | Cancer Therapies |
| Alcon | Zug, Switzerland | Eye-Care Products |
| , | Acquired by Arterex, Jun 2023 | |
| , | ||
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| , | Main employees gone for months as of Nov 2025 | |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| MSM Protein Technologies | , | Gone Jun 2019 |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Halo Genomics | , | Bought by Agilent |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| , | Website down Jul 2025 - Dec 2025 | |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Stago | Asnières sur Seine, France | Diagnostics |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Lyman Biopharma Consulting | , | Switched to writing |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| , | No news Jun 2021 - Jan 2026 | |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| , | Renamed AtaiBeckley | |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| Akermin | , | Closed |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| imarc | , | Acquired by Avania, Jun 2021 |
| Quartet Medicine | , | Wound down, Nov 2017 |
| Integrated Genomics | , | Changed to Igenbio |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Vascular Biogenics | , | Now VBL Therapeutics |
| Glysantis | , | Shut down Late 2020 |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Genfit | Cambridge, MA | Drug Discovery |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Getinge | Vendôme, France | Medical Technology |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| TCXpress | , | Renamed BlueSphere Bio |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| AtCor Medical | , | Now part of CardieX |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| Regentys | , | Acquired by Generex, Jan 2019 |
| , | No news 2019 - Jul 2026 | |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| SomaServe | , | Renamed ViaNautis Bio |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| Biocode Hycel | , | Website gone |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Roowin | Riom, France | Chemical Synthesis |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| , | Website down Dec 2025 - Apr 2026 | |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Retroject | , | Seems gone |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Rezolute | Bend, OR | Biologics |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| , | Website down Aug 2025 - Jan 2026 | |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| Cell Technology | , | Acquired by ICT |
| Absynth Biologics | , | Website Gone Jan 2019 |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Whole Biome | , | Renamed Pendulum Biosciences |
| NetBio | , | Renamed ANDE |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| |
Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| Stago | Gennevilliers, France | Diagnostics |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Stada | Belgrade, Serbia | Generics |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| Phenoquest | , | Website gone, Oct 2015 |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Akesis LLC | , | Bankrupt 2015 |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| AmplifyBio | , | Shut down Apr 2025 |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Scion NeuroStim | , | Presumed gone |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| Pneumolabs | , | Dissolved Sep 2018 |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| , | Renamed ElisiGen, Dec 2025 | |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| Novogene | Beijing, China | Genomic Services |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| 3T Biosciences | South SF, CA | TCR Therapies |
| , | Website down Feb 2026 - Aug 2026 | |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Eco Quest | , | Now Cynata Therapeutics |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| GlycoRegImmune | , | Changed name to GRI |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| One Drop | , | Gone Dec 2024 |
| Amachumu Bio | , | Shut down April 2021 |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| , | Renamed ExGen Dx, Jul 2025 | |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Commence Bio | , | Gone 2018 |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| RxCelerate | Cambridge, UK | Contract Services |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| , | Renamed Ladder Bio, Nov 2025 | |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Endogene.bio | Paris, France | Data Platform for Uterine Health |
| Bracco | Plainsboro, NJ | Imaging |
| Minimally Invasive Devices | , | Shut down |
| TesoRx | Menlo Park, CA | Formulations platforms |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| Mandrake Bio | Bengaluru, India | AI-native protein design and gene editing infrastructure |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Almac | Durham, NC | Pharmaceutical Services |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| , | Website down Apr 2026 - Aug 2026 | |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Hybrigenics | , | Renamed ATON |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| AzurRx | , | Merged into First Wave Bio |
| Narus Development Solutions | , | Gone |
| GeneTrol | , | Merged with CytoPharm |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| Synosia Therapeutics | , | Acquired by Biotie |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| CardioCreate | , | Shut Down Jun 2020 |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| SunMed | , | Renamed AirLife |
| RJS Biologics | , | Shut down Feb 2019 |
| Parion Sciences | Durham, NC | Mucosal Targets |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| ResVerlogiX | Calgary, AB | Small Molecules |
| , | Website down Oct 2025 - Jan 2026 | |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| Alliqua | Langhorne, PA | Hydrogels |
| PRI Research | , | Renamed Wake Clinical |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Zensun | , | Website gone Jan 2019, Chinese company |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Ansh Labs | Webster, TX | Diagnostics Products |
| , | No news 2020 - Apr 2026 | |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| Riverain Technologies | Miamisburg, OH | Imaging |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| , | Website down Jan 2026 - May 2026 | |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| Progyny | New York, NY | IVF products |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Collate Software | San Francisco, CA | Paperwork Streamlining |
| Intellikine | , | Bought by Millennium 2011 |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| ions.bio | Planegg, Germany | Biomarkers |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| Suvoda | Portland, OR | Clinical Trial Software |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Boston Scientific | St. Paul, MN | Medical Devices |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| TauTaTis | , | Shut down 2011 |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Refined Diagnostics | Münster, Germany | Lasers |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Macrogen | , | Renamed Psomagen, 2019 |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| Alife | San Francisco, CA | AI-powered IVF |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| BojiMed | Guangzhou, China | Clinical Research |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Therix Medical | , | Seems gone |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| TriVirix | , | Now Nortech Life Sciences |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| Cimple Biotechnology | Hong Kong, China | Rapid POC Diagnostics |
| Alfasigma | Bologna, Italy | Small Molecules? |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| NeurAegis | , | Seems gone, Sep 2022 |
| , | No news 2017 - Apr 2026 | |
| Alt Bioscience | , | Now PDx Biotech |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| LinKinVax | , | Rebranded as EnnoDC |
| Admescope | Oulu, Finland | ADME-tox services |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Website down Jan 2026 - May 2026 | |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Avrin | Liverpool, UK | Clinical Research |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Regis Chromatography | Morton Grove, IL | Synthesis & Separations |
| DL Develop | , | Website gone, Dec 2018 |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Active Implants | , | Renamed NUsurface |
| , | Inactive May 2025 | |
| Entelos | , | Bankrupt |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Piramal | Digwal, India | CDMO |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Vesper Medical | Wayne, PA | Venous Stent |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Elixir Medical | Milpitas, CA | Stents |
| Sapient Discovery | , | Shut down, Jan 2018 |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| Large Scale Biology | , | Shut Down |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| Cambrian Bio | New York, NY | Small Molecules |
| Theracos | , | Renamed TheracosBio |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| , | Acquired by Medicover, Apr 2026 | |
| RecomGenex | , | Renamed TargetEx Biosciences |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Outset Medical | San Jose, CA | Dialysis Device |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Minakem | Dunkerque , France | API Manufacturing |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| Recida Therapeutics | , | |
| , | Liquidating, Mar 2025 | |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| , | Winding down Apr 2026 | |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| , | Renamed Ceryvyn Therapeutics, Jul 2026 | |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Novotech | Seoul, Korea | Clinical Research |
| Resilience | Blue Ash, OH | Biomanufacturing |
| Innogenix | Amityville, NY | Generics |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Ovation.io | Portland, ME | LIMS |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Avalyn Pharmaceuticals | Boston, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Iontas | , | |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| West-Ward | , | Now part of Hikma |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| |
Neuried, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Inscopix | Mountain View, CA | Miniature Microscope |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| , | Acquired by UCB, Jun 2026, $2B | |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Nexus BioPharma | , | No news 2017-2022 |
| , | Website down Jan 2026 - May 2026 | |
| BZL Biologics | , | Gone 2003 |
| CeNeRx | , | Shut Down, 2013 |
| Aspreva | , | Acquired by Vifor Pharma |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| AlphaGenix | , | Gone 2014 |
| Transmed Oncology | , | Gone? |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| , | Website redirecting to Tedan Surgical Systems, Jul 2026 | |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| Ascend Genomics | , | Shut down |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| , | Acquired by Bausch + Lomb, Mar 2026 | |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Scilucent | Fairfax, VA | Regulatory Consulting |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Tuevol Therapeutics | , | Gone by 2020 |
| Predictive Therapeutics | , | Renamed NeoTX |
| DermaRite | North Bergen, NJ | Foam Dressing |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| Clontech | , | Now Takara Bio |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| BioPointe Scientific | , | Subsumed into parent |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| XtalPi | Shanghai, China | AI Drug Design |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| Nanobac Pharmaceuticals | , | Gone |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| LENSAR | Orlando, FL | Cataract Laser |
| Amivas | Waterford, Ireland | Antimalarial |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| VedaLab | Cerisé, France | IVD rapid tests |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| , | Reportedly Closed Mar 2026 | |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| , | Acquired by Instem, Jul 2025 | |
| Incyte | Wilmington, DE | Small Molecules |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Sebia | Lisses, France | Electrophoresis |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| Immutics | , | Renamed TrueBinding |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Arraystar | Rockville, MD | Microarrays |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| , | Gone 2023, website taken over by a designer | |
| Abselion | Cambridge, MA | Biologics Quantification |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| , | Website down Feb 2026 - Aug 2026 | |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| Altiris Therapeutics | , | Presumed Gone |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| argenx | Boston, MA | Antibody therapies |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| AccuVein | Medford, NY | Vein Visualization |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Stellartech Research | Milpitas, CA | Electronic device development |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| Pfizer | Clondalkin, Ireland | Biologics |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| Medicure | Winnipeg, MB | Small Molecule |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| Metamark Genetics | , | Shut down 2018 |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Axial3D | Belfast , UK | 3D printing for medical use |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| , | Website down Oct 2025 - Feb 2026 | |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| , | Acquired, Jun 2025 | |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Alliance Spine | San Antonio, TX | Spinal implants |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| , | Website down Jul 2025 - Jan 2026 | |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| GMP-Orphan France | , | Renamed Orphalan |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| PregLem | , | Acquired by Richter, Oct 2010 |
| Analiza | Cleveland, OH | Physicochemical Services |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Kasocio | , | Liquidated, Dec 2019 |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Advanced Vision Science | , | |
| NeuroTransit | , | Behind on taxes in CA |
| Ribon Therapeutics | , | Shut down May 2024 |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Hygtia Therapeutics | , | |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| Trigemina | , | Shut down Aug 2020 |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| Tisucor | , | Shut down Feb 2020 |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Grifols | Durham, NC | Biologics |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Salvat | Madrid, Spain | Small Molecules |
| , | Website down Dec 2025 - Apr 2026 | |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| Pfizer | Kalamazoo, MI | Manufacturing |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Clinical Microbiomics | , | Merged into cmbio |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Alibion | , | Website down May 2021 - Sep 2021 |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| , | Liquidation, Jun 2025 | |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| Phasiq | , | Website gone Jul 2018 |
| Aliri | Loos, France | Contract Mass Spec |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Apharm | , | Now Biofarma Group |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| Antabio | Labège, France | Antibacterial drugs |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| Stada | Vršac, Serbia | Generics |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| PharmaGap | , | Shut down 2013 |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Kegelbell | , | Shut down, Dec 2024 |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Quanta Biosciences | , | Renamed QuantaBio |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| , | Website down Jun 2025 - Dec 2025 | |
| Prommune | , | |
| Vrata Therapeutics | Cambridge, | |
| Alkermes | Waltham, MA | Small Molecules |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| LabTwin | , | Merged with Labforward |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| ArisGen | , | Only employee has four other jobs |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| PolyTherics | , | Joined Antitope to become Abzena |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| MolPlex | , | Insolvent, 2016 |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| , | Renamed Cyaris, Apr 2026 | |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Mepha | Basel, Switzerland | Generics |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| , | Now PiSA USA | |
| Acrosian | Princeton, NJ | Biometrics CRO |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Oncorus | , | Liquidated, Jun 2023 |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| , | Liquidating Jul 2026 | |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Quanticate | Hitchin, UK | Clinical Research |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| Axplora | Shanghai, China | Purification Systems |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| Neurokos | , | Gone. No info |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| Antitope | , | Now part of Abzena |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Pharmaron | Louisville, KY | R&D Services |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| Gilead | Oceanside, CA | Small Molecules |
| APCRA | , | Shut down 2020 |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| , | Website down Jun 2025 - Dec 2025 | |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| , | Website down Jan 2026 - May 2026 | |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| NextPharma | Limay, France | Contract Research & Development |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| Maplehurst Genetics International | , | Website gone |
| PPL Therapeutics | , | Sold in 2003 |
| Getinge | Gothenburg, Sweden | Medical Technology |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| RetiPharma | , | Dissolved Nov 2019 |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Patrin Pharma | Skokie, IL | Generics |
| Palingen | , | Renamed IGM Biosciences |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Lunit | Seoul, Korea | AI Image Analysis |
| , | Renamed EarliPoint Health, Oct 2025 | |
| Novotech | Bangalore, India | Clinical Research |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| , | No news 2019 - Aug 2026; Residential Address, Jun 2025 | |
| Solvay | , | Bought by Abbott 2010 |
| Wacker | San Diego, CA | Biologics CDMO |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| CorDx | San Diego, CA | Diagnostics |
| Getinge | Suzhou, China | Medical Technology |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Artera | Los Altos, CA | AI Diagnostics |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| RegeneraTEch | , | Renamed Regencor |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| YishengBio | , | Now YS Biopharma |
| , | ||
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| A2IDEA | , | Only employee left Jan 2024 |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Spyryx Biosciences | , | Shut down 2019 |
| CMD Bioscience | , | Closed, 2015 |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| , | Shut down Jan 2024 | |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Macleods Pharmaceuticals | Mumbai, India | Generics |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Novo Nordisk | Beijing, China | Inflammation Research |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Blau Farmaceutica | São Paulo, Brazil | Biosimilars |
| SereDigm | , | Gone Nov 2009 |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| , | Acquired by Lantheus, Jan 2025 | |
| Meissner | Camarillo, CA | Lab Systems |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Proacta | , | Gone 2014 |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| PepVax | , | Gone 2024 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Spherics | , | Bankrupt |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| SemBioSys | , | Bankrupt, Jul 2012 |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| IQVIA | Lenexa, KS | Clinical Research |
| NeoDiagnostix | , | Website Down Feb 2025 |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Zeto | Raleigh, NC | Dry Electrode EEG System |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| AsymBio | Jinshan, China | Biologics CDMO |
| Spriaso | , | No news 2019 - May 2025 |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| , | Gone Jul 2026, portions acquired by Axol Bioscience | |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| Predicine | Hayward, CA | Liquid Biopsy |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| , | Renamed KadisBio | |
| Cobalis | , | Basically Bust |
| Accutome | , | Now part of Keeler |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| LyoTechnica | , | Gone |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Genoma | , | Website gone May 2021 |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Aviria Biosciences | , | Disappeared |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| , | Assets Acquired by Synaptiq Therapeutics, Jul 2026 | |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| VM Discovery | , | 20 yr old company with no info on website |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| Protypia | , | |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| Evvy | New York, NY | At-home vaginal microbiome test |
| MicroPort | Arlington, TN | Medical Devices |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Adlon Therapeutics | , | |
| Protox Therapeutics | , | Now Sophiris Bio |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| Bionas Discovery | , | Website gone Jun 2018 |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Surface Logix | , | Bought by Nano Terra |
| Vicus Therapeutics | , | Gone 2019 |
| Integer | Salem, VA | Medical & Surgical Devices |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| , | Acquired by DEC Group 2021 | |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| Sirana Pharma | , | Merged with Apexis Bio |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Bioneeds | Bangalore , India | Contract Research |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Abcellute | , | Dissolved, Sep 2016 |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Best Vascular | , | Now Best Vascular Novoste |
| Genstruct | , | Now Selventa |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| , | Acquired by CorMedix, Sep 2025, $300M; Filed bankruptcy Dec 2019, acquired out of bankruptcy outright by Deerfield Mar 2020; fka Rib-x | |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Artivila Biopharma | Shenzhen, China | Artificial Intelligence-Driven Drug Discovery |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Lupin | Baltimore, MD | Generics |
| NeuroFx | , | Renamed Theratome Bio |
| , | Acquired by Sun Pharma, May 2025 | |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| AniTech Limited | Hong Kong, China | AI-EEG Platform |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Bayer | Bergkamen, Germany | Small Molecules |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| QuA Vodis | , | Gone |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| ProteoVec | , | Website gone Jul 2015 |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| , | Acquired by Axora Medical, Jan 2026 | |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Medtronic | Warsaw, IN | Medical Devices |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| Accellacare | Hickory, NC | Clinical Research |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Selten Pharma | , | Gone 2017 |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Biotia | Long Island City, NY | AI Genomics |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Vie Diagnostics | , | Renamed Phoresa |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| seqWell | Beverly, MA | Sequencing Service |
| , | Website down Jan 2026 - May 2026 | |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| D-Pharm | , | Website Gone, Aug 2016 |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| RSSL | Wokingham, UK | Analytical Services |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Pfizer | Surrey, UK | Consumer Healthcare |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| |
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Healionics | Seattle, WA | Biomaterials for devices |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| , | Website down Oct 2025 - Feb 2026 | |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| NeuroNano Pharma | , | Gone 2018 |
| MacroPore | , | Gone |
| , | Merged with Avere Therapeutics, Jul 2026 | |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| SR Pharma | , | Now Silence Therapeutics |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| AVEO Oncology | Boston, MA | Small Molecules |
| , | Website down Feb 2026 - Jul 2026 | |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| SERB Pharmaceuticals | Paris, France | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| TaiwanBio | , | Website gone Oct 2021 |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| Targanta | , | Bought by The Medicines Company |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| ImmBio | , | Shut down Nov 2019 |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Genera Medix | , | Apparently sold all products |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| Delpharm | Lille, France | Contract Manufacturing |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| Thyritope Biosciences | , | Closed Oct 2016 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| Adrenergics | , | Gone Sep 2017 |
| , | No news 2020 - Nov 2025 | |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| SK Biotek | , | part of SK pharmteco |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| Nuvik Therapeutics | , | No website, very little info |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| OP2 Drugs | , | Website gone Jan 2020 |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Ergomed | Prague, Czech Republic | Clinical Research |
| Scientia Advisors | , | Website gone Jul 2015 |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| Align Technology | Tempe, AZ | Teeth alignment |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| Action Pharma | , | Abbott acquired product, 2012 |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Unither Pharmaceuticals | Paris, France | CDMO |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| Boehringer Ingelheim | Vienna, Austria | Small Molecules, Biologics, CDMO |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| eZono | Jena, Germany | Virtual Needle Guidance |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Proteintech | Wuhan, China | Research Antibodies |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| , | Shut down late 2025 | |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Eos Biosciences | , | Shut down Oct 2020 |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Baxter | Alliston, ON | Medication Delivery |
| Confer Health | , | Shut down 2021 |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Sinotherapeutics | Shanghai, China | Generics |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Hovione | Osaka, Japan | Contract Manufacturing |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Getinge | Tournefeuille, France | Medical Technology |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Abbott | Donegal, Ireland | Diagnostics |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| Accellacare | Wilmington, NC | Clinical Research |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Pharmexa | , | Merged into Affitech, May 2009 |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| preclinics | Potsdam, Germany | Contract Research |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Angiosonics | , | Shut down 2002 |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| AddBIO | , | Gone Oct 2023 |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| Bio-Detail | , | Website gone Feb 2023 |
| CGT Global | Folsom, CA | Tissue Sourcing |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| ActoBio Therapeutics | , | Brought into Precigen |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Hope Medicine | Pudong, China | Antibody Therapy |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| Cell Matrix | , | Acquired by Cancervax |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Celtaxsys | , | No longer active, Aug 2020 |
| AuraSense Therapeutics | , | Renamed Exicure |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Trillium Diagnostics | , | Closed Jul 2016 |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| , | No news 2015 - Jan 2026 | |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| Phoresa | , | Shut down Mar 2018 |
| Zivena | , | Gone |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| LexaMed | Toledo, OH | Life Science Consulting |
| , | Website down Oct 2025 - Jan 2026 | |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Remedium Bio | Needham, MA | Gene Therapy |
| Vivex Biologics | Atlanta, GA | Tissues |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| ERT | , | Renamed Clario, Nov 2021 |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Tella | , | Website down May 2023 - Dec 2023 |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| NuVascular Technologies | , | Shut down Nov 2021 |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| , | No news 2019 - Jul 2026; Residential Address, Mar 2020 - Sep 2024 | |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Applied Integrin Sciences | , | Gone |
| MLAB Biosciences | Needham, MA | Biologics |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| Cydan Development | , | Shut down Sep 2021 |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| , | Shut down Dec 2023 | |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| MURO PHARM | , | Dissolved, May 2007 |
| Coferon | , | Renamed BlinkBio |
| Oscor | , | Acquired by Integer, Dec 2021 |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| Trimeris | , | Merged with Synageva |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Orbus Pharma | , | Website Gone |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Weatherwax | , | Renamed General Proximity |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Yposkesi | , | part of SK pharmteco |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Lifebit | London, UK | Genetic Data Analysis |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| Avenge Bio | , | Shut Down Jul 2024 |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Flen Pharma | , | Now Flen Health |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Rgene | , | Late business filings Aug 2021 |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| New Brunswick Scientific | , | Merged into Eppendorf |
| Nido Surgical | , | Shut down Apr 2022 |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Kesios Therapeutics | , | Closed down according to investors |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Myoposity Therapeutics | , | Gone |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| , | Website down Jan 2026 - May 2026 | |
| Evolve BioSystems | , | Renamed Infinant Health |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Copley Scientific | Nottingham, UK | Test equipment |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| COR Clinical Research | , | Shut down after owner passed |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Nano Science | , | Acquired by EAG, 2006 |
| NextImmune | , | Renamed NXI Therapeutics |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Octagen | , | Assets bought by Ipsen, 2008 |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| CTG Pharma | , | Gone |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Atlas Genetics | , | Renamed Binx Health |
| GeneAssess | , | Gone |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Elite Research Institute | , | Gone, May 2018 |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Beardsworth | , | Bought by TFS International 2013 |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| , | Assets Acquired by Klotho, Sep 2025 | |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Inform Genomics | , | Website Gone Nov 2018 |
| Y's Therapeutics | , | Website Gone |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Real Research | Krakow, Poland | 3D Cell Culture |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Medtronic | North Haven, CT | Medical Devices |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| QL Biopharm | Beijing, China | Biologics |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Analogic | Canton, MA | Medical Imaging |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| OD-OS | Irvine, CA | Retinal Laser |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| PeriCor Therapeutics | , | Website Gone |
| Kylin Therapeutics | , | Sold |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| Xencor | San Diego, CA | Antibody Discovery |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Taligen Therapeutics | , | Acquired by Alexion |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Precise Bio | , | Gone 2023 |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| , | Website down Jun 2025 - Dec 2025 | |
| Prochon Biotech | , | Acquired by Histogenics |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| Tecomet | Kenosha, WI | CNC Machining, EDM, Finishing, Special Processes, Orthopedics, SET, Advanced Surgical |
| Calibrant | , | Closed |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| , | Website down Nov 2025 - Apr 2026 | |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| Osteolab | , | Spam site |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| QT Ultrasound | , | Renamed QT Imaging |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| Zenosense | , | No website, shell company Nov 2020 |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Medicure | Holetown, Barbados | Small Molecule |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Ecopharm | , | Website down Feb 2021 |
| BBB Therapeutics | , | Bankrupt 2015 |
| PKPD International | , | Attack website |
| Helus Pharma | Toronto, ON | Psychedelics |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| Dante Labs | , | Seems to be Dante Genomics now |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| , | Website taken over, Nov 2025 | |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| EsbaTech | , | Bought by Alcan |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| , | Acquired by Instem, Jul 2025 | |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| PepLib Biotech | Metuchen, NJ | Peptides |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Bruker | Billerica, MA | Scientific Instruments |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| JCL Bioassay | , | Renamed CMIC |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| Tarsa Therapeutics | , | Product rights acquired |
| Biohit | Helsinki, Finland | Diagnostics |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| , | Website down Feb 2026 - Jul 2026 | |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| Zai Lab | Beijing, China | Small Molecules |
| , | Website down Jan 2026 - Mar 2026 | |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| NeuMed | , | Website four years since update, no employees on LI |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Instil Bio | Dallas, TX | Cell Therapy |
| Roche | Welwyn, UK | Small Molecules |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Bionorica | Neumarkt, Germany | Plant-derived Medicines |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| OxStem | , | Shut down 2021; Oxford spinout |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Fornax Biotech | , | Dissolved Jun 2021 |
| deCODE Biostructures | , | Now Emerald Biostructures |
| Stryker | San Jose, CA | Medical Devices |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| , | Website down Nov 2025 - Apr 2026 | |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Actis Biologics | , | Gone |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Lusochimica | , | Owned by Menarini |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Centinel Spine | West Chester, PA | Spinal Implants |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| Pace | San German, PR | Analytical Testing, CDMO |
| ViroMed | , | Renamed Helixmith |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| , | Website down Mar 2026 - Aug 2026 | |
| Amarox | Riyadh, Saudi Arabia | Generics |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| , | Acquired by Sun Pharma, May 2025 | |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Rytvel Biotechnology | , | |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| , | Website taken over, Jan 2026 | |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Lindus Health | London, UK | CRO |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Genexa | , | Shut down before Nov 2023 |
| Sinusys | , | Shut down 2023 |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| |
Branford, CT | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| , | Website down Jan 2026 - May 2026 | |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Tenomix | London, ON | Robotic Tissue Grossing |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Redpoint Research | , | Gone 2019 |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| Piramal | Mumbai, India | CDMO |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| , | Website down Aug 2025 - Jan 2026 | |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| Evestra | San Antonio, TX | Women's Health |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| IntelliGenome | Houston, TX | CRISPR Diagnostics |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Onyvax | , | Assets Apparently Acquired |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| , | Acquired by Merck, May 2026, $6.67B | |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Allsino | Hangzhou, China | APIs, Excipients |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| Breathometer | , | Product didn’t work, pivoted |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Silktap | , | Liquid silk. Site gone |
| Barc Lab | , | Renamed Cerba Research |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Rheos Medicines | , | Shut down Dec 2022 |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| InsightRX | San Francisco, CA | Dosing Model |
| , | Website down Dec 2025 - May 2026 | |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Terapio | , | Website Gone, Sep 2020 |
| Biocodex | Gentilly, France | Microbiota Treatments |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Curry Pharmaceuticals | , | Closed 2008 |
| BianoGMP | Gera, Germany | Oligonucleotides |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Bone's Technology | Shenzhen, China | Bone Density Analysis, Surgical Planning |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| Quanticate | Raleigh, NC | Clinical Research |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Nanometrix | London, UK | Nanoscale Data on Extracellular Vesicles |
| Neuromatters | , | Shut down Dec 2019 |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| US Genomics | , | Now PathoGenetix |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Point Biomedical | , | Liquidated Jul 2008 |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Gencove | Long Island, NY | Genome Sequencing |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| Xyntek | , | Segment of non-life science business |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| , | Website down Feb 2026 - Jun 2026 | |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| Biowest Therapeutics | , | Website Gone |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Fujifilm Biotechnologies | Morrisville, NC | Biologics Development & Manufacturing |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Grid Biosciences | New Territories, China | Vaccines |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| TargeGen | , | Bought by Sanofi 2010 |
| Compugen | Holon, Israel | Biologics |
| , | Renamed Allotera Therapeutics, Jul 2026 | |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| , | Acquired by Bio-Techne, Apr 2021, $215M + $105M milestones | |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Allez Health | Carlsbad, CA | Biosensors |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| Gen-probe | , | Acquired by Hologic 2012 |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Virco | , | Bought by J&J |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Sequella | , | Ancient website ©2017, last news 2017 |
| , | No news 2021 - Jul 2026 | |
| Phenomix | , | Shut Down 2011 |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Pharmaron | Coventry, RI | API Manufacturing |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| BioAMPS | , | Gone |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| Anacalypsis Therapeutics | Spata, Greece | LRRK2 Targeting Therapies |
| Gerard Biotech | , | Lab supplies, seems defunct |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| , | Website down Dec 2025 - Apr 2026 | |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| BioAro | Calgary, AB | LIMS, Omics software |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| Proteintech | Rosemont, IL | Research Antibodies |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| Catalyz | , | Gone |
| bioRASI | Aventura, FL | Clinical Research |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| CO.DON | Leipzig, Germany | Cell Therapies |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Cellenion | Berlin, Germany | Single Cell Testing |
| OpenClinica | Needham, MA | Clinical Study Software |
| Endomag | Cambridge, UK | Biopsy Tracer |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| , | Pivoted to blockchain, Sep 2025 | |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| NTC | Milan, Italy | Generics |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| , | Shut down Oct 2025 | |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| Theramex | London, UK | Women's Health |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| |
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| Organon (2) | Jersey City, NJ | Women's Health |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| Protelica | , | Dissolved, Dec 2006 |
| CanSino Biologics | Tianjin, China | Vaccines |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| CRIO | Boston, MA | eClinical Software |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| Corza Medical | Boulder, CO | Surgical Devices |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| Skylit Medical | , | Renamed Clarify medical |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| , | Website down Jan 2026 - May 2026 | |
| Benchling | San Francisco, CA | Biotech Software |
| Allergenics Inc | , | Closed Mar 2007 |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Molecular Throughput | , | Rebranded as mtibio |
| RelonChem | Cheshire, UK | Generics |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| CytRx | , | Renamed LadRx Sep 2022 |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| , | Merged with Cohance, May 2025 | |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| Abbott | Longford, Ireland | Diagnostics |
| Formurex | Stockton, CA | Contract Research |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| , | Shut down 2025 | |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| PulmoGeniX | , | No business filings 2016-2020 |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| , | Website down Feb 2026 - Aug 2026 | |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sunho Biologics | Nanjing, China | Biologics |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| CompleGen | , | Shut down Aug 2021 |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Roche | Burgess Hill, UK | Diagnostics |
| Akkadix | , | Gone 2001 |
| Quantificare | Maringa, Brazil | Medical Imaging |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| , | Website down Jul 2025 - Mar 2026 | |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Parexel | Durham, NC | Clinical Research |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Novometrics | , | Dissolved Dec 2019 |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Transdermal Technologies | , | Website Gone |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Commave Therapeutics | , | |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| Abnovo | , | Gone |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| Moximed | Fremont, CA | Joint treatment |
| Labshire | Cambridge, MA | Laboratory Consulting |
| MiNK Therapeutics | New York, NY | Cell Therapy, CAR-T |
| Bicolor | Belfast, UK | Lab Assays |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Haupt Pharma | , | Merged with Aenova |
| Jade Biosciences | Virtual, US | Biologics for Autoimmune Diseases |
| Neurotronik | , | Most employees moved to InnerPulse |
| , | Renamed PICO BioScience, Jun 2026 | |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Bankruptcy, Jun 2026 | |
| ViThera Pharmaceuticals | , | Gone 2017 |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| BalinBac Therapeutics | , | Gone 2018 |
| Nesher Technologies | , | Shut down Oct 2017 |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Stemnovate | Cambridge, UK | Research Cells |
| LeukoSite | , | Acquired by Millennium 1999 |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| , | Acquired by Beacon Biosignals, Apr 2025 | |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Bioxene | , | Website gone, Company Presumed gone |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Diatos | , | No website, founded 1999 |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| , | Shut down Jan 2025 | |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| Venclose | , | Acquired by BD, Dec 2021 |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| Oxehealth | , | Pivoted to mental health platform |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| PsiThera | Watertown, MA | Oral Small Molecules |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| , | Website down Oct 2025 - Feb 2026 | |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| Journey Colab | , | Shut down Jan 2025 |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| , | Dissolved Jun 2019 | |
| Siga | New York, NY | Small Molecules |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| Sightera Biosciences | Antwerp, Belgium | Generative Drug Design |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| Ana-Gen Technologies | , | Gone post 2001 |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| , | Website down Nov 2025 - Apr 2026 | |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| Envision Pharma | , | Merged with UBC |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Niagara Biosciences | , | No info, Aug 2022 |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| EuBiologics | Seoul, Korea | Vaccines |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| C/M/C Biologics | , | Now CMC Biologics |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| Mediso | Budapest, Hungary | Medical Imaging |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| BiOM | , | Now BionX Medical |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| , | Website down May 2025 - Dec 2025 | |
| PX Biosolutions | , | Gone |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| GeoVax | Smyrna, GA | Vaccines |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Tgen Tech | , | Renamed Annoviant |
| GenEscence | , | Gone Jul 2013 |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Tecomet | Farmington Hills, MI | Bone In-Growth Coating, Bearing Surface Solutions |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Calchan | , | Shut down Dec 2020 |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| , | No news 2020 - Jul 2026 | |
| AblaCor | , | Shut down May 2019 |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Diamante | Trento, Italy | Immunotherapies Manufacured in Plants |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| 14M Genomics | , | Shut down, Feb 2016 |
| Intrexon | , | Renamed Precigen |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| FHC | Bowdoin, ME | Medical Devices |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| AndroBioSys | , | Presumed gone |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Genopraxis | , | Founder has new job, Jul 2021 |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| InnoCare | Beijing, China | Cancer Treatments |
| |
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| ImmunArray | , | Shut Down, 2021 |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| BioGaia | Stockholm, Sweden | Probiotics |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Apicore | Gujarat, India | API Development & Manufacturing |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Holloway America | Springfield, MO | Vessels, Tanks |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Pion | Billerica, MA | Dissolution Data |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| , | Acquired by Chiesi, Apr 2023 | |
| Trident Lifeline | Surat, India | Generics |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| AstronauTx | London, UK | Alzheimer's Treatments |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| Vyaire Medical | , | Acquired by Trudell Medical, rebranded as Jaeger medical Nov 2024; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Guardion Health Sciences | , | Shut down |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Stryker | Flower Mound, TX | Medical Devices |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| BioVolutions | , | Gone |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Essential Pharma | Egham, UK | Generics |
| Zylacta | , | No news 2015 - Oct 2024 |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Broken String Biosciences | England, UK | Gene Edited Cell & Gene Therapy |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Syneos Health | Morrisville, NC | Clinical Development |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| Relion | , | Shut down 2015? |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| Novitium Pharma | East Windsor, NJ | Generics |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| , | Website gone Aug 2026; All execs gone, Sep 2025 | |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Pfizer | McPherson, KS | Sterile Injectables |
| bioMerieux | Cambridge, MA | Diagnostics |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| Genomics | Oxford, UK | Human Genetics Platform |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| , | Subsumed into Synoptics | |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Novonesis | North Rocks, Australia | Enzymes |
| Cytiva | Piscataway, NJ | Medical Devices |
| Luvak Lab | , | Dissolved 2013 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Zephyr AI | McLean, VA | AI Data Analysis |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Onkor Pharma | , | 10 year old company with no product or website |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Getinge | Mumbai, India | Medical Technology |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| NovaDel Pharma | , | Business dissolved 2014 |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| GnuBIO | , | Bought by Bio-rad |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| Amrita Therapeutics | , | Seems gone |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Anthra Pharmaceutical | , | Gone |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pentapharm | Basel, Switzerland | APIs |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| CSL Behring | King of Prussia, PA | Biologics |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| VivoSphere | Auburn, AL | Human-like Research Tissue |
| Gilson | Middleton, WI | Lab Supplies |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| ALX Oncology | South SF, CA | Immuno-oncology |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| MatTek | Ashland, MA | Cell Products, Services |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| OptiVia Medical | , | Website looks pretty terrible |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Angioslide | , | Gone, Oct 2009 |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Quantum SI | Branford, CT | Single-molecule NGS |
| ArKal Medical | , | Gone 2012 |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| PepLib Biotech | ZhuZhou, China | Peptides |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Macusight | , | Effectively acquired by Santen, 2008 |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Virapur | , | Acquired by Microbiologics, 2017 |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| |
Cheshire, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| , | Website down Jan 2026 - May 2026 | |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| , | Abbott alums in Sioux Falls, ID, none on Linkedin Mar 2025 | |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| GeNO | , | Renamed Vero Biotech, 2018 |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| , | Website down Jul 2025 - Dec 2025 | |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Genaera | , | Dissolved |
| ALTx Therapeutics | , | Small Molecule Therapies |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| OPIS | Milan, Italy | Clinical Research, Consulting |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Par Health | St. Louis, MO | Generics |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| LifeMax | , | Part of AmMax |
| Tecomet | Sheffield, UK | Casting, CNC Machining, EDM, Finishing, Forging, Heat Treatment |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| Abbott | Sylmar, CA | Device Manufacturing |
| , | Shut down Dec 2025 | |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Ximedica | Providence, RI | Medical Device Services |
| Dharma Therapeutics | , | Gone, 2013 |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Loop Therapeutics | , | Shut down Jan 2021 |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Curium | , | Dissolved, Mar 2015 |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| Creative Enzymes | Shirley, NY | Enzymes |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| CelerDx | , | Tiny startup that went nowhere |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| Pharmazz | Greater Noida , India | Small Molecules |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| Androclus Therapeutics | , | Closed, May 2007 |
| August Bioservices | Nashville, TN | Research & Development Services |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| Metis Laboratories | , | |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Eversana | Chicago, IL | Commercialization Consulting |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Beacle | , | Founder gone, no info |
| , | Acquired by Olon, 2024 | |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| AngioChem | , | All employees gone, no info, presumed gone |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| Enesi Pharma | , | Renamed aVaxziPen |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| Sanofi | Reading, UK | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| , | Website down May 2025 - Dec 2025 | |
| Vernay | Griffin, GA | Fluid Control Solutions |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| OccuRx | , | Merged into Certa Therapeutics |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| Nusano | Valencia, CA | Radioisotopes |
| , | Website down Oct 2025 - Feb 2026 | |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| , | Gone before Dec 2025 | |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Dirui Industrial | Changchun, China | Automated Assays |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| Amerging Biotechnolgies | Mohali, India | Bioprocess Equipment |
| Cetero Research | , | Renamed PRACS Institute |
| EPISONA | , | Gone Nov 2018 |
| Arete Therapeutics | , | Out of Business |
| Interferon Source | , | Bought by PBL Assay Science |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| PreventAGE Health Care | , | fka Journey Biosciences |
| ResearchDx | Irvine, CA | Diagnostics |
| , | Website down May 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| , | Shut down Oct 2025 | |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Califia Bio | , | Shut down May 2020 |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Texcell | Gronau, Germany | Contract Research |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| VB Spine | Allendale, NJ | Spinal Implants |
| Roche | Mississauga, ON | Small Molecules |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| Flux Biosciences | , | Shut down, ~2022 |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| CytoLogix | , | Gone, Sep 2012 |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| |
Medolla, Italy | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Getinge | Antalya, Turkey | Medical Technology |
| Evopoint Biosciences | Waltham, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Gene Express Inc | , | bankrupt? |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| genOway | Lyon, France | Rat and cell models |
| Coley Pharma | , | Acquired by Pfizer |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| APSciences | , | Website gone Aug 2022 |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Compliment Corporation | , | Closed Dec 2011 |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| AGILeBiotics | , | Shut down 2024? |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Starpharma | Abbotsford, Australia | Antibacterial |
| ResMed | San Diego, CA | Medical Devices |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Lian Medical | Beijing, China | Medical Devices |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| CoAxia | , | Closed down Spring 2013 |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Macleods Pharmaceuticals | Vagra, India | Generics |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| Archimedic | West Chester, PA | Medical Device Consulting |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Cellex | , | Presumed Gone |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| Lean Biologix | Norfolk, MA | Consulting |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| Solvanix | , | Shut down Nov 2023 |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Neocis | Miami, FL | Dental Surgery Robots |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Nephros | South Orange, NJ | Dialysis Devices |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| , | Website down Jul 2025 - Dec 2025 | |
| Microsize | Quakertown, PA | Microionization CDMO |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| bioMerieux | Lombard, IL | Diagnostics |
| Neurogene | New York, NY | Genetic Therapies |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| , | No news 2015 - Aug 2026 | |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| Cellink | Kyoto, Japan | Bioprinting |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Oxitope | , | Shut Down Feb 2019 |
| Ribocept | , | Defunct |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| Accellix | Jerusalem, Israel | On-demand Assays |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Duramed | , | Acquired by Barr Labs 2001 |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| Centocor | , | Renamed Janssen Biotech |
| GeneProt | , | Shut down Apr 2005 |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| DDi | Singapore, Singapore | Clinical Software |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| , | Website down Jul 2025 - Dec 2025 | |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| , | Acquired by Altivera Medical, Mar 2026 | |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| ScionxBio | Cambridge, UK | Extended-release RNA |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Calmune | , | Liquidated |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Genomadix | Kanata, ON | Portable PCR |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Personalis | Fremont, CA | Genome Services |
| , | Renamed Mighty Therapeutics, Jun 2026 | |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| , | Website down Sep 2025 - Feb 2026 | |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| PluriSelect | El Cajon, CA | Cell Separation |
| Okairos | , | Acquired by GSK, May 2013 |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| ProPharma Group | Washington, DC | Consulting |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| Angel Biotechnology | , | Bankrupt, 2013 |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Medice | Iserlohn, Germany | Small Molecules |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Baxter | Singapore, Singapore | Medication Delivery |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| Microbia-pe | , | Renamed Microbia |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| Bicycle Therapeutics | Lexington, MA | Peptides |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Bridge Laboratories | , | Gone 2013 |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| VB Spine | Leesburg, VA | Spinal Implants |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| TidalSense | Cambridge, UK | Respiratory Diagnostics Platform |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| , | Website down Feb 2026 - Jul 2026 | |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Alkermes | Wilmington, OH | Small Molecules |
| Metris Therapeutics | , | Presumed Gone |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| NuAire | Plymouth, MN | Lab Equipment |
| SelectX | , | Website hacked; No updates since 2011 |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| , | Shut down Mar 2026 | |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Combs Lab | , | Website gone Dec 2016 |
| , | Website 404 Sep 2025 - Apr 2026 | |
| GenturaDx | , | Bought by Luminex 2012 |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Assay Designs | , | Now Enzo Life Sciences |
| , | Shut down Jan 2024 | |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| Axplora | Pompey, France | CDMO Services |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| , | Renamed Virchow | |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| , | Liquidating Jul 2025 | |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Genae Associates | , | Acquired by IQVIA |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| Samil Pharmaceutical | Seoul, Korea | Eye Drops, Aseptic Filling, Formulation |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Antisoma | , | Became investment company |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| , | Acquired by CQ Medical, Oct 2023 | |
| , | Website down Jan 2026 - Apr 2026 | |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Novaliq | Cambridge, MA | Drug Delivery |
| , | Renamed Nexalis Therapeutics, Jan 2026 | |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| , | Acquired by Biogen, Jun 2026, $1B milestones | |
| , | No news 2019 - Jul 2026 | |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| AJES Life Sciences | , | Renamed L2P Research |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| , | Acquired by Aptean, Oct 2016 | |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| , | Website down Sep 2025 - Dec 2025 | |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Chesapeake Biological Labs | , | Now known as Cangene |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| Microphage | , | Bankrupt Jun 2013 |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| DiagnoCure | , | Liquidated, Apr 2016 |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Boston Scientific | Valencia, CA | Medical Devices |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| MiniVax | , | Gone Jan 2016 |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Iquum | , | Acquired by Roche, Apr 2014 |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Zai Lab | Suzhou, China | Small Molecules |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| Stago | Franconville, France | Diagnostics |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| Solano Pharmaceuticals | , | Website gone |
| Vanquish Oncology | , | No news 2015-2021 |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Verana Health | San Francisco, CA | Clinical Database |
| Dexcom | San Diego, CA | Glucose Monitors |
| PluroGen Therapeutics | , | Gone 2013 |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| Metrad Biosystems | , | Website gone |
| MyOme | Palo Alto, CA | Genomic Analysis |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| , | Subsumed into Synoptics | |
| Blackfynn | , | Gone Apr 2022 |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| Kerecis | Arlington, VA | Wound Healing |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| , | Now part of LTS, Dec 2025; fka Renaissance Pharma | |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Olema Oncology | San Francisco, CA | CAR T brake |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Genomas | , | Website gone May 2020 |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| , | Acquired by ETAP Group, Oct 2023 | |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Macleods Pharmaceuticals | Daman, India | Generics |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Sorbent Therapeutics | , | Gone post 2014 |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| AltaRex | , | Gone |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Ascenta Therapeutics | , | Gone |
| Symbollon | , | Gone |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| Argonaut Manufacturing Services | Carlsbad, CA | CMO specializing in formulation, filling, finishing and final kitting. |
| O-Ray pharma | , | Inactive Jun 2022 |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Gran Med | , | Gone |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| , | Website down Jan 2026 - Mar 2026 | |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| , | Renamed Torpedo Therapeutics | |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Biovail | , | Merged with Valeant |
| ViroPharma | , | Bought by Shire Jan 2014 |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| VaxNewMo | , | Renamed Omiose |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| Ataia Medical | , | Website taken over Jan 2024 |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Medpace | Cincinnati, OH | Clinical Research |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| , | Subsumed into parent, Jul 2026 | |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Piramal | Rabale, India | CDMO |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| South Coast Clinical Trials | , | |
| , | Website down Aug 2025 - Jan 2026 | |
| Pharmathen | Marousi, Greece | Generics |
| NeurAxon | , | No updates since 2008 |
| SERB Pharmaceuticals | Cambridge, MA | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| , | Website taken over Feb 2026 | |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| Hemab Therapeutics | Frederiksberg, Denmark | Bleeding Disorder Treatments |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| , | Rebranded as VivoSim, Apr 2025 | |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Biorelate | Manchester, UK | AI Data Curation |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Astek Diagnostics | Baltimore, MD | UTI Diagnostic |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| Formulatrix | Bedford, MA | Lab Automation |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Derma-Cell Research | , | Website gone Nov 2019 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| GlycoSolutions | , | Closed Aug 2015 |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Samsara Sciences | , | Shut Down Mar 2020 |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| , | Shut down 2024 | |
| Immunovaccine | , | Rebranded IMV, 2018 |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| TheraCoat | , | Renamed UroGen Pharma |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Xcelthera | , | Shut down, Apr 2021 |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| , | Website down Dec 2025 - Apr 2026 | |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Onorach | Dundee, UK | Clinical Trial Management |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Greenstone Biosciences | Palo Alto, CA | |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| Acuvax | , | Pivoted to investments, 2014 |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| , | Liquidating, May 2026 | |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| Seeker Biologics | , | Shut down May 2023 |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Quantamerix | , | No info since 2012, never registered in MA |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| Xhale | , | Acquired by Philips, Aug 2018 |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| KALA BIO | Arlington, MA | Drug Delivery |
| Baxter | Deerfield, IL | Medication Delivery |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Avax Technologies | , | Gone |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| NewVac | , | |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Ymir Genomics | , | Dissolved Jun 2021 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| NemaPharm | , | Defunct? |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Enterin | , | Website taken over Feb 2025 |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Tryton Medical | , | Shut down Jan 2021 |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Biosion | Nanjing, China | Bispecific Antibody |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| Axial Biotech | , | Closed Mar 2013 |
| Lupin | Mandideep, India | Generics |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Tico Bio | , | Renamed Inso Biosciences |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| , | Website gone Feb 2026 | |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| SJ Pharma | , | Website gone, Nov 2018 |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| Medelis | Thompson's Station, TN | Clinical Research |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| CardioCanary | , | Founders gone. Doubt it's active |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Stimwave | , | Bankrupt, Oct 2022 |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Fujifilm Biotechnologies | Hillerød, Denmark | Biologics Development & Manufacturing |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| , | Acquired by Genesis Biotechnology Group, Mar 2017 | |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Multerra Bio | , | Bankrupt May 2021 |
| Optovue | , | Renamed Visionix Sep 2021 |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| Sopherion | , | Website taken over, Mar 2017 |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Corcym | London, UK | Implants, Instruments |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| , | Website down Aug 2025 - Jan 2026 | |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Penwest | , | Bought by Endo |
| Santen | Emeryville, CA | Ophthalmics |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| , | Website down May 2026 - Jul 2026; LI gone Jul 2026 | |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| ECI Biotech | , | Gone 2016 |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| Cambridge, | Small Molecules for bacterial infections | |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Bausch Health | Laval, QC | Small Molecules |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Nymirum | , | Renamed Base4, Feb 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| , | Acquired by Processa Pharmaceuticals, Jul 2026 | |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| , | Merged into Meridian Bioscience | |
| Curexsys | , | Dissolving, Jul 2024 |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| , | Website down Aug 2025 - Jan 2026 | |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| Perlegen | , | No Site |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| , | Acquired by Immedica, Feb 2025 | |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| Carolus Therapeutics | , | Business revoked in CA |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| La Jolla Biologics | , | Website gone Nov 2014 |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| , | Acquired by Source BioScience, Apr 2025 | |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| , | Renamed Alethio Therapeutics | |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| ArunA Biomedical | , | |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Salgomed | , | Shut down Apr 2022 |
| , | No news 2020 - Jun 2026 | |
| nitec Pharma | , | Merged with Horizon Pharma |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| QT Vascular | , | Website gone Jan 2024 |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Mighty Therapeutics | Needham, MA | Mitochondrial disease therapies |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Syneos Health | Princeton, NJ | Clinical Development |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| , | Website down Dec 2025 | |
| Spirometrix | , | Renamed Spirosure |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| Altos Therapeutics | , | Gone Jun 2019 |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| RheoSense | San Ramon, CA | Viscometers |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| Kereos | , | Seems gone |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| Cardima | , | Bankrupt Dec 2010 |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| Stromedix | , | Bought by Biogen Idec 2012 |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Pharos iBT | , | aka Pharos iBio |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Qualicaps | Whitsett, NC | Capsules |
| Medtronic | Cincinnati, OH | Medical Devices |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| MSD | Dublin, Ireland | Women's Health Products |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| Viravaxx | , | |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| Kulira Technologies | , | Website Gone Oct 2016 |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| Laborie | Portsmouth, NH | Medical Devices |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| Piramal | Aurora, ON | CDMO |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| , | Website down Dec 2025 - Apr 2026 | |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| PRA International | , | Now PRA Health Sciences |
| Kar Bioanalytical | , | Seem gone |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| , | Crypto Pivot, Oct 2025 | |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| EndoLogic | , | Seems inactive, Aug 2023 |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| Panacos | , | Believe they are inactive |
| ImmuneMed | , | Shut Down |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Zomanex | , | Gone Oct 2019 |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Inductive Bio | Virtual, US | Compound Optimization |
| Sonus Pharma | , | Merged with Oncogenex |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Neoantigenics | , | Website gone Sep 2017 |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| , | Now a Genovis product/service, Jul 2026 | |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| V-gene | , | Website gone, Aug 2017 |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Lacer | Barcelona, Spain | Small Molecules |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Imcyse | , | Liquidating, Jun 2025 |
| , | Shut down Jan 2026 | |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| , | Liquidating Jun 2026 | |
| , | ||
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| DNAtrix | , | Gone late 2023 |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| GenoImmune | , | |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| FemtoVox | , | |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| , | Website down Nov 2025 - Apr 2026 | |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Avam | Odessa, FL | Clinical Diagnostics |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Bayer | Mexico City, Mexico | Small Molecules |
| Regenerative Sciences | , | Took on Regenexx product name |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| Noscira | , | Liquidated |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| MantaBio | Beverly, MA | Real-time PCR System |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Eden Biodesign | , | Bought by Watson |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| MetaMol Theranostics | , | Gone |
| Amigenics | , | Gone |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| , | Renamed Hubot, May 2026 | |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Cymbiotics | , | Gone 2019-2020 |
| Syncro Medical | Langhorne, PA | Software development |
| Epigen | , | Renamed Egenix, 2002 |
| ARx | Glen Rock, PA | Pharmacokinetic CRO |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| BioDevek | , | Formerly LabCentral, seems gone |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| ProtonDx | London, UK | Diagnostics |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| , | Website down Nov 2025 - Apr 2026 | |
| Biolab | Mississauga, ON | Small Molecules |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| Getinge | Växjö, Sweden | Medical Technology |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| Promethera Biosciences | , | Renamed Callaion |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| , | Website down Jul 2025 - Jan 2026 | |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| LemnaGene | , | Acquired by Biolex 2005 |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Roche | Buonas, Switzerland | Diagnostics |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Menarini | Firenze, Italy | Small Molecules |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Exelixis | Alameda, CA | Small Molecules |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| SDC | Higley, AZ | Clinical Data Services, Virtual Trials |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Brightflow Medical | Paris, France | Heart Failure Device |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Neuro Bio | Oxford, UK | T14 Blocker |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Resilience | Mississauga, ON | Biomanufacturing |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Quentis Therapeutics | , | Shut down late 2020 |
| Percivia | , | Shut Down 2012 |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Stada | Bad Vilbel, Germany | Generics |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| , | Website down Jul 2025 - Dec 2025 | |
| 3B BlackBio | Bhopal, India | PCR products |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Organogenesis | Canton, MA | Biologics |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| PharmaVigilant | , | Gone 2014 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| BioMap | Palo Alto, CA | AI Models |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| , | Website down Jun 2025 - Dec 2025 | |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Blu Biotech | , | Website down May 2023, CEO gone |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| , | Website down May 2025 - Oct 2025 | |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Eminent Services | Frederick, MD | Drug Services |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| FIT Biotech | , | Bankrupt Feb 2019 |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Longevica Therapeutics | Belmont, CA | Longevity Therapies |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| , | Website down Dec 2025 - Apr 2026 | |
| Biological Dynamics | , | Shut down Jul 2024 |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| Mastel Surgical | Rapid City, SD | Surgical Devices |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| Amarin | Dublin, Ireland | Small Molecules |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| StemCell2MAX | , | Website gone Apr 2019 |
| , | Renamed Create Medicines, Oct 2025 | |
| ObsEva | , | Shut down Feb 2024 |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| , | Shut down Jun 2026 | |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Norgine | Vienna, Austria | Specialty Pharma |
| , | Website gone Feb 2026 - Apr 2026 | |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| Advanz Pharma | London, UK | Specialty Generics |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| MitoStem | , | Seems gone |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| , | Website down Jan 2026 - May 2026 | |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| , | No news 2020 - Dec 2025 | |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Arxspan | , | Renamed SciY |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Cougar Biotechnology | , | Bought by J&J |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| , | Website down Feb 2026 - Jul 2026 | |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| SourceMDx | , | Assets Sold |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| RepRegen | , | Gone, 2014 |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| Jina Pharmaceuticals | , | |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| |
Princeton, NJ | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Vessel Biosciences | , | Shut down Mar 2023 |
| , | Website down Jan 2026 - May 2026 | |
| , | Website taken over, Jan 2026 | |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| , | Acquired by Syner-G BioPharma Group | |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| ProPharma Group | Deerfield, IL | Consulting |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Animas | , | Shut down, Oct 2017 |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Crown Bioscience | San Diego, CA | Drug Development |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Soletics | , | Website gone Jun 2021 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| , | Looks like 1 employee, no news 2017-Aug 2026 | |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| 10BioSystems | , | Website Gone, Apr 2016 |
| LabConnect | Johnson City, TN | Lab Services |
| , | Website down Sep 2025 - Dec 2025 | |
| , | Website down Sep 2025 - Dec 2025 | |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Acumed | Hampshire , UK | Medical Implants |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Biomoles | , | Closed Sep 2017 |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Alfacell | , | Now Tamir Biotechnology |
| Cellzome | , | Acquired by GSK Mar 2012 |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Ergomed | Kiev, Ukraine | Clinical Research |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Novoresearch | , | Gone 2014 |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| Cherry Biotech | Paris, France | Organoid Culture |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| ChondroGene | , | Now GeneNews |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| , | No news 2021 - Jun 2026 | |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| Telephus Medical | , | Now Telephus Biosciences |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Keenova | Malvern, PA | Small Molecules |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| SuperX | , | Gone |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Cirina | , | Merged with Grail, May 2017 |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| NS Pharma | Paramus, NJ | Small Molecule |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Western States Biopharmaceuticals | , | Website Taken Over |
| InterGenetics | , | Assets auctioned |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| AdipoGenix | , | Gone Jun 2012 |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| , | Website, Linkedin gone Jul 2026; Founder relocated and became postdoc | |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Ketal Biomedical | , | Gone |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| Parexel | Newton, MA | Clinical Research |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| Santen | Osaka, Japan | Ophthalmics |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Epigenetix | , | No annual report filed 2013-2019 |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments, CMO |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| , | Shut down Mar 2026 | |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| STB Lifesaving Technologies | , | Website gone |
| Helix3 | Morrisville, NC | Contract Research Lab |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Akubio | , | Bankrupt Sep 2007 |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| Genomica | , | Shut down Sep 2022 |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| StromaCyte | , | Small time, no info. Defunct |
| Steris | Mentor, OH | Contamination Control |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| , | Website taken over Jun 2026 | |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| Rox Medical | , | Gone 2019 |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Pivotal BioSciences | , | Shut down late 2018 |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| , | Renamed Proxoma, Jan 2026 | |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| DIAsource Diagnostics | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| Visitube | , | No website Mar 2020 |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Regulaxis | , | No news 2020-2024 |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| PnuVax | , | No news 2017 - Aug 2024 |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Trilations | New York, NY | Strategic Consulting |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| CureGene | Shanghai, China | |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| PhosPrint | Athens, Greece | Laser Bioprinting |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Glenveigh Medical | , | Website down Sep 2024 |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| alphaSyx Therapeutics | , | Gone |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| Origen Therapeutics | , | Gone |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| , | Acquired by Esperion, Apr 2026 | |
| , | Website down Dec 2025 - Apr 2026 | |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Advarra | Columbia, MD | Regulatory Consulting |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| , | Website down Sep 2025 - Feb 2026 | |
| Stasys Medical | , | Shut down Feb 2025 |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| AndroScience | , | Ancient website, no news 2014-2023 |
| ReSync Bio | , | Acquired by Benchling 2025 |
| OverT Bio | New York, NY | Cell Therapy |
| Novacta | , | Website Gone, no info |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| , | Website down Dec 2025 - Apr 2026 | |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| , | Website down Dec 2025 - Jun 2026 | |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| MOgene | St. Louis, MO | Genomic Services |
| Peritia | Morrisville, NC | Consulting |
| CMP Therapeutics | , | Dissolved, May 2015 |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| , | Website down Feb 2026 - Jul 2026 | |
| , | Shut down Nov 2025 | |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| Iconovo | Lund, Sweden | Inhalation Technology |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| Ufovax | , | Renamed Uvax Bio? |
| BGI | Hong Kong, China | Genetic Testing |
| ClinOne | Needham, MA | Clinical Patient Platform |
| ImmuNext | , | Website gone Feb 2025 |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| Upstate Biotechnology | , | Closed 2005 |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Microislet | , | Bankrupt 2008 |
| , | Website down Sep 2025 - Dec 2025 | |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Neuron23 | South SF, CA | AI-drug discovery |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| Remepy | New York, NY | Software-Pharmaceutical Integration |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| Antios Therapeutics | , | Shut down Feb 2023 |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| Panaxia | Lod, Israel | Medical Cannabis |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Akceli | , | Shut down, Sep 2004 |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Linical | Stuart, FL | Clinical Research |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Rhaeos | Evanston, IL | Shunt Monitor |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| , | No news 2021 - Aug 2026 | |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| F2G | Cheshire, UK | Antifungals |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Heart Repair Technologies | , | |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| , | Acquired by Medici Therapeutics, Nov 2025 | |
| Bioventus | Cordova, TN | Orthobiologics |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Tecomet | Lille, France | Case Design, CNC Machining, Finishing |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| KVK Tech | Newtown, PA | Generics |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| DNA Worldwide | Frome, UK | DNA Testing |
| CiVentiChem | , | Acquired by Sterling Pharma |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| NK CellTech | Shanghai, China | Cell Therapies |
| , | Website down Jun 2025 - Dec 2025 | |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Medallion Therapeutics | , | Shut down 2018 |
| , | Website down Mar 2026 - Aug 2026 | |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Innexus Biotechnology | , | Gone |
| Axxam | Milan, Italy | Drug discovery services |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Mesoblast | New York , NY | Regenerative Medicine |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| , | One person, possibly moved to AK | |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| SanBio BV | Uden, Netherlands | Antibodies |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Best Vascular Novoste | , | Now Novoste |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Imris | Chaska, MN | Image Guided Therapy Solutions |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Roche | Tucson, AZ | Diagnostics |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Acumed | Beijing, China | Medical Implants |
| Gene ID inc | , | Website taken over |
| SynGenSys | Sheffield, UK | DNA, Cell Products |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| IntelligentMDx | , | Shut down Feb 2015 |
| DxTech | , | Seems gone. No info Dec 2015 |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Enterey | Irvine, CA | Life Science Consulting |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| |
Toulouse, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Promaxo | Oakland, CA | Small form MRI |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Regulatory Pharma Net | Pisa, Italy | Regulatory Consulting & Market Access |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| CTK Biotech | Poway, CA | Diagnostics |
| , | Renamed medac pharma production, Apr 2026 | |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Aitia | Cambridge, MA | Analytics |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| Apnex Medical | , | Shut down, Aug 2013 |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Plexision | Pittsburgh, PA | Diagnostics |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Berlex | , | Now Bayer |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Cytiva | Amersham, UK | Medical Devices |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| NX Development | Lexington, KY | Brain Imaging |
| ObvioHealth | New York, NY | Clinical Study Software |
| Trudell Medical | London, ON | Inhalation Devices |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Gene Logic | , | Bankrupt |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| , | Renamed MindWalk, Sep 2025 | |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Vadovations | , | No info. 2012 SBIR grant |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| , | Acquired by Charles River, Apr 2019 | |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| PharmaDerm | , | Part of Sandoz |
| Enovalife | Paris, France | Biometrics and medical writing services |
| TETmedical | Fair Haven, NJ | Nanomedicine company focused on in vitro diagnostics |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Traferox Technologies | Mississauga, ON | Organ Preservation |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| PromoCell | Heidelberg, Germany | Cellular Products |
| |
Göttingen, Germany | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| , | Website down May 2025 - Dec 2025 | |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Roche | Mannheim, Germany | Diagnostics |
| , | Website down Aug 2025 - Jan 2026 | |
| Vivacy | Archamps, France | Aesthetic Medicine |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Tides Medical | Lafayette, LA | Biologics |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Allenex | , | Bought by CareDx, Apri 2016 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| , | Renamed Aspen Neuroscience | |
| NsGene | , | Website gone |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| SutroVax | , | Renamed VaxCyte |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Vexev | Surry Hills, Australia | Vascular Imaging |
| CeQur | Luzern, Switzerland | Insulin pump |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Abogen | Suzhou, China | mRNA |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| HEC | , | Website down Dec 2024 - May 2025 |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Apobiologix | Toronto, ON | Biosimilars |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| , | Acquired by Hologic, Aug 2019, $85M - 46% ownership as of Aug 2019 | |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| Aptyx | Tempe, AZ | Device CDMO |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| , | Website down Jun 2025 - Dec 2025 | |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Abazyme | , | Dissolved Jun 2017 |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Genyro | San Francisco, CA | DNA Construction Technology |
| ChemPacific | Baltimore, MD | Chemicals |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| AngioCure | , | Employees all gone, Nov 2017 |
| MetaOptima | Vancouver , BC | Skin Analytics |
| ErVimmune | Lyon, France | Cancer Vaccines |
| Zelos Therapeutics | , | No site |
| MMI Genomics | , | Assets bought by Neogen |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Digene | , | Merged with Qiagen |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| SEQENS | Ecully, France | APIs, Ingredients |
| SoftGenetics | State College, PA | Software for genetic analysis |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Droice | New York, NY | AI Clinical Data |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| OxOnc Development | , | Website gone Apr 2018 |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Vision Genomics | , | Website Gone, Jul 2016 |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| BioArra | , | Bought by VWR Nov 2016 |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| Therorna | Beijing, China | RNA Therapies |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| , | Website taken over Jul 2026 | |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Hikma | London, UK | Medication Delivery |
| Alkermes | Dublin, Ireland | Small Molecules |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Pinnaxis | Noida, India | Pharmacovigilance |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| Unilife | , | Bankrupt, Apr 2017 |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| ProtAffin | , | Winding Down |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| , | No news 2020 - Jun 2026 | |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| CSL Behring | Bradley, IL | Biologics |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Tequesta BioScience | , | Defunct |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| Ocis Biotechnology | , | |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Alvea | , | Shut down Oct 2023 |
| Madera Biosciences | , | Shut down Aug 2020 |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| , | Gone Jan 2026 | |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| Oblenio Bio | Lexington, MA | T-cell engager antibody |
| Vaccibody | , | Renamed Nykode Therapeutics |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| Abbott | Mississauga, ON | Diagnostics |
| , | Website down Feb 2026 - Jul 2026 | |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| Catalina Pharma | , | No info 2017-2022 |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Diamante | Verona, Italy | Immunotherapies Manufacured in Plants |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| CoreMap | Burlington, MA | High-resolution cardiac electrophysiology mapping system |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| , | Website down Dec 2025 - Feb 2026 | |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| AFID Therapeutics | , | Gone 2012 |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| icotec | Altstätten, Switzerland | Spinal Implants |
| , | Shut down June 2024 | |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Abcam | Cambridge, UK | Antibodies |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Merix Bioscience | , | Renamed Dendrix |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| , | Acquired by Crypto Group, Jan 2025 | |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Inventprise | Redmond, WA | Vaccines |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| Eurogentec | Seraing, Belgium | Biologics |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| , | Winding down Apr 2026 | |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Amarin | Bridgewater, NJ | Small Molecules |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| , | Acquired by Bruker, Sep 2020 | |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| NeoVentures | London, ON | Custom Aptamers |
| PMG Research | , | Now Acellacare |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| GemacBio | , | Renamed PolyNeuroS |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| , | Shut down May 2025 | |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Abbott | Clonmel, Ireland | Stents |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| , | Website down Feb 2026 - Jul 2026 | |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| Integer | Clarence, NY | Medical & Surgical Devices |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| LinkChem | Shanghai, China | CDMO |
| , | Acquired by bioMerieux, Sep 2013, $450M + debt | |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Evocutis | , | Pivoted to investments |
| Sonosine | Kidlington, UK | Medical Imaging |
| CyteGen | , | 2015 founded, website never active |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Boca Pharmacal | , | Bought by Qualitest |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| Savage Medical | , | Renamed Averto Medical |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| , | No news 2020 - Dec 2025 | |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Medtronic | Danvers, MA | Medical Devices |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Biotix | San Diego, CA | Lab Consumables |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| , | No news 2022 - Mar 2026 | |
| AbRegen | , | Website gone, Mar 2019 |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Rad AI | San Francisco, CA | Radiology Software |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Auris Medical | , | Renamed Altamira Therapeutics |
| Precursion Biosciences | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Celerion | Montreal, QC | Clinical Research |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| Carrington Labs | , | Changed Name to DelSite |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| iBio | San Diego, CA | Antibody Therapies |
| , | Website taken over Feb 2026 | |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Impulse Dynamics | Marlton, NJ | Implantable Heart Failure Devices |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Five Star Products | , | Liquidated |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Nvelop Therapeutics | , | |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| QSV Biologics | , | Website Gone |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| , | Website down Jun 2025 - Oct 2025 | |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| Affymax | , | Dissolved 2014 |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| , | Website down, CEO gone Apr 2026 | |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Surgisense | , | Presumed gone |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Karius | Redwood City, CA | Diagnostics |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Redwood City, CA | Merged with Kira Pharmaceuticals, Jul 2026 | |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Nigra | , | Acquired by Vernalis |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Safecor Medical | , | Shut down Apr 2021 |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Rapalogix Health | New York, NY | TORC1 inhibitors |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| Esculon | , | Seems defunct, employees gone |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| VG Life Sciences | , | Shell company |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| CorePharma | Middlesex, NJ | Contract Small Molecule Manufacturing |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Vanadis Laboratories | , | Gone 2018 |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| TCG GreenChem | Ewing, NJ | |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| Novotech | Auckland , New Zealand | Clinical Research |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| |
Framingham, MA | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| |
Cambridge, UK | Isogenica: VHH antibody discovery CRO. World's largest synthetic libraries, 100+ programmes, clinical candidates, discovery timelines cut in half. |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| iuvo | Rochester, NY | Ophthalmic Clinical Research Services |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Ziphius Vaccines | Zwijnaarde, Belgium | Self-amplifying RNA Vaccine |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Anergix | , | Shut down Mar 2009 |
| Cancer Insight | , | Renamed LumaBridge |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| , | Website taken over Jun 2026 | |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Olon USA | Concord, OH | Contract Research |
| Sanofi | Midrand, South Africa | Biologics |
| , | Website down Oct 2025 - Jan 2026 | |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Allogene Therapeutics | South SF, CA | CAR-T |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| , | Renamed Streamline Scientific | |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| , | Shut down May 2026, assets to Innoviva | |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Endothelix | , | Now owned by American Heart technologies |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| , | Renamed Valion Bio, Apr 2026 | |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| BioTheryX | San Diego, CA | Small Molecules |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| InteKrin | , | Owned by Coherus Biosciences |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Clario | Philadelphia, PA | Clinical Services |
| Inverness Medical | , | Renamed Alere 2011 |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Folia Biotech | , | Website Gone May 2018 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Vyteris | , | Bankrupt 2012 |
| CytoMol (2) | , | SF-based, Looks gone |
| Norganoid | Macclesfield, UK | Organoid Technology |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| , | Website down Jul 2025 - Dec 2025 | |
| , | Acquired by Embecta, Mar 2026 | |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| NovoMedix | San Diego, CA | Small molecules |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| Cdymax | Bangalore, India | APIs |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| EyeCyte | , | Gone 2014 |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Elegen | San Carlos, CA | DNA writing |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| EuroAPI | Paris, France | API Production, CDMO |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| Apolife | , | Renamed Biosavita |
| Coral Drugs | New Delhi, India | APIs |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| MindRank | Shanghai, China | AI Drug Discovery |
| Tyrian Diagnostics | , | Gone 2012 |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Medispect | , | Shut Down 2013 |
| Certego Therapeutics | , | Seems gone May 2023 |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Eurand | , | Now Aptalis |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Medtronic | Mounds View, MN | Medical Devices |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| Plexanome | , | Gone 2018 |
| Medtronic | Minneapolis, MN | Medical Devices |
| Serometrix | , | More of an aspiration than a company |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| , | Website down Dec 2025 - Apr 2026 | |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| Lectus Therapeutics | , | Sold off product |
| , | Website down Jan 2026 - May 2026 | |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Ionpath | , | Shut down Feb 2025 |
| Mankind Pharma | New Delhi, India | OTC? |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Atherotech | , | Shut down Feb 2016 |
| Doctor Pack | Bangalore, India | Packaging |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Medica | , | Gone before 2019 |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| Xact Medical | , | Website down Mar 2024 |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Merged with Vaxanix | |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| AlphaVax | , | No employees on LI. Not sure active |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| ADMA Biologics | Ramsey, NJ | Biologics |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Vanguard Therapeutics | , | |
| Avance Clinical | Firle, Australia | Clinical Research |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| CO.DON | Teltow, Germany | Cell Therapies |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| , | LI gone Jul 2026; Website down Jun 2026 - Aug 2026 | |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Lusis | Hayward, CA | Diagnostics |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Avexa | , | Renamed Novita Healthcare |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| , | Website down Apr 2026 - Aug 2026 | |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| MetaStat | , | Website gone May 2019; Shell Company |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Accellacare | Cary, NC | Clinical Research |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Universal Precision Instruments, Inc. | , | |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| Gene Labs | , | Bought by GSk 2008 |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| ERBC | Baugy, France | Non clinical CRO |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Mednoxa | , | Website gone Jan 2020 |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| Lupin | Mumbai, India | Generics |
| , | Website down Jan 2026 - May 2026 | |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| FFE Therapeutics | , | Shut down Dec 2013 |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Anazen Diagnostics | , | Part of Cardiox |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| BioConsulting International | , | Ancient website, presumed defunct |
| Roche | Pleasanton, CA | Diagnostics |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Genuine Biosystem | Chennai, India | IVD Products |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| Abbott | Alameda, CA | Diabetes Care |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Sebra | Tucson, AZ | Tube Sealer |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| Vali Nanomedical | , | Gone 2016 |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Cristers | Suresnes, France | Generics |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Hesperos | Orlando, FL | Human-on-a-chip |
| Celest Therapeutics | , | |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| Clinical Scientist Group | , | Website gone, employee gone |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| TruGenomix | , | Renamed Polaris Genomics |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| Zyagen | San Diego, CA | Life Science Reagents |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| CreaGen | Woburn, MA | Drug Discovery Services |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| Embecta | Parsippany, NJ | Diabetes Care |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| APT Therapeutics | , | Shut down Mar 2019 |
| Orthogonal LLC | Chicago, IL | Medical device software |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| , | Renamed ABS Bio | |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| , | Website down May 2025 - Sep 2025 | |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| Sentien Biotechnologies | , | Shut down late 2021 |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Verus Pharmaceuticals | , | Dissolved |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| , | Acquired by AbbVie, Aug 2025 | |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| , | Shut down Apr 2026 | |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| WiseGene | , | Website gone jan 2020 |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Bio-ops | , | Now SVA |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Roche | Laval, QC | Diagnostics |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Synakis | Toronto, ON | Ocular Delivery Hydrogel |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Formation Bio | New York, NY | AI Drug Discovery |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| CLCbio | , | Acquired by Qiagen, 2013 |
| , | Renamed aMBR Genomics, Jun 2026 | |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| Antyra | , | Gone |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Gennova Bio | Pune, India | mRNA vaccine |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| IQVIA | Durham, NC | Clinical Research |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| Abnovel | , | Gone Jul 2010 |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| Anumana | Cambridge, MA | AI ECG reading |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Halloran Consulting Group | Boston, MA | Consulting |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| , | Renamed Helyx Industries | |
| ImmuneWorks | , | Website gone, Apr 2018 |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| , | ||
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Minimus Spine | , | Only real employee now full-time at another company |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| , | Acquired by Bora CDMO, Oct 2022 | |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Dornier MedTech | Sillingy, France | Urology Devices |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| , | Website down Jul 2025 - Jan 2026 | |
| MWG Biotech | , | Owned by Eurofins |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| Cairn Research | Kent, UK | Scientific Instruments |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| Osteologix | , | Liquidated, Sep 2015 |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| Wacker | Munich, Germany | Polymers, Resins |
| Leukosight | , | Gone, website is online pharmacy now |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Afaxys | Charleston, SC | Women's Health |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| JABio | , | Shut Down May 2021 |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| Targeson | , | Website gone, Mar 2017 |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| Parexel | Sheffield, UK | Clinical Research |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| Bayer | Bitterfeld, Germany | Small Molecules |
| Bakhu Pharma | , | Bankrupt, location sold |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| , | Website down Feb 2026 - Aug 2026; Bankruptcy Jul 2025 | |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| 149 Medical | , | Shut down Dec 2022 |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| Novelty Nobility | Seongnam, Korea | ADCs |
| TcLand Expression | , | Website Gone |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Modular Medical | San Diego, CA | Insulin Pump |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| 1859, Inc. | , | Shut down Jul 2023 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Isolagen | , | Reorganized as Fibrocell Science |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| , | No news 2020 - Apr 2026 | |
| IMUNA PHARM | Michalany, Slovakia | Contract Manufacturing |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| QuatRx | , | Acquired by Shionogi, 2017 |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| , | Acquired by IQVIA | |
| DFE Pharma | Goch, Germany | Excipients |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| Chanelle Pharma | Amman, Jordan | Generics |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| Camurus | Lund, Sweden | Specialty medicines |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| , | Website down Jan 2026 - May 2026 | |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| REPROMEDIX | , | Gone 2012 |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| AccelaPure | , | Bankrupt 2007 |
| Synlogic | , | Shut down Sep 2024 |
| Transcera | Boston, MA | Extracellular Protein Degradation |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Platelet BioGenesis | , | renamed PlateletBio |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| RSIP Vision | San Francisco, CA | Image analysis algorithms |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| PowderMed | , | Acquired by Pfizer 2006 |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Diality | Irvine, CA | Hemodialysis System |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Nina Biotherapeutics | , | Gone, after 2015 |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| Curis | Lexington, MA | Small Molecules |
| Bioasis Technologies | , | Closing down Jun 2023 |
| LumaBridge | San Antonio, TX | Clinical Research |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| RoslinCT | Edinburgh, UK | Stem Cells |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Ipca Laboratories | Mumbai, India | APIs |
| , | Renamed Silthera, Apr 2026 | |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| Symansis | Timaru, New Zealand | Reagents |
| Innovagen | Lund, Sweden | Custom antibody development |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Piramal | Mahad, India | CDMO |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| MabPrex | , | Out of business, 2016 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| ConjuChem | , | Bankrupt 2011 |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| Gamma Therapeutics | , | Gone |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Optical Imaging | , | Website taken over, Mar 2019 |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Sitka Biopharma | , | Website gone Jan 2022 |
| SulfaGENIX | , | Website gone, Jan 2019 |
| Genlantis | , | Acquired by AMSBIO |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| Wetlin Research Associates | , | Centerwatch only |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| SegAna | , | Website down May 2021 - Sep 2021 |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| Embody | Norfolk, VA | Soft Tissue Healing |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| VytronUS | , | Shut down Mar 2020 |
| Covalent Bioscience | , | Shut down, 2025? |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| Neurosave | , | Gone 2018 |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| RK Pharma | Pearl River, NJ | Generics |
| Alera Labs | Durham, NC | Contract Research & Services |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| , | ||
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Syndexa Pharm | , | Closed Jul 2013 |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| MabCo | , | Renamed Agenix |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| Mendelian | London, UK | Rare Disease Diagnosis |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| Xeris Biopharma | Chicago, IL | Injectables |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| Peptone | London, UK | Translational Biophysics |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Affinimark Technologies | , | Gone |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Seer | Redwood City, CA | Early Detection |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Tecomet | Cork, Ireland | CNC Machining, Finishing, Inspection, Plastics Machining, Shotpeening |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| , | Website down Oct 2025 - Jan 2026 | |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| Alms Therapeutics | , | Gone Jul 2022 |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| Splice Histology | Worcester, MA | Histopathology Services |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| Venebio | Glen Allen, VA | Consultants |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Körber | Hamburg, Germany | Production Monitoring Software |
| AM2PAT | , | Trouble with contaminated products, gone |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Duality Biologics | Shanghai, China | ADCs |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| SoBran | Falls Church, VA | Preclinical Services |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Effipharma | , | Marked as closed by Google |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Horiba Instruments | Irvine, CA | Equipment |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| IGF Oncology | , | Shut down 2022 |
| Anaheim Clinical Trials | , | Now CenExelACT |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| KeraCure | , | Gone 2014 |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| , | Website down Jul 2025 - Dec 2025 | |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Novartis | Emeryville, CA | Diagnostics |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| , | Subsumed into Synoptics | |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| Hovione | Mumbai, India | Contract Manufacturing |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| CovX Research | , | Bought by Pfizer |
| Louisville Bioscience | , | Now LBIdx |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Kate Therapeutics | , | |
| Accellacare | Winston-Salem, NC | Clinical Research |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Nuventra Pharma Sciences | , | Now Allucent |
| ZipBio | Seattle, WA | Compact Proteins |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| CereScan Corp | , | Renamed CereHealth |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| , | Renamed Singulera, Nov 2025 | |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| Nanosonics | Manchester, UK | Ultrasound |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| Nensius Research | , | Website Gone |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Apath | , | No website update since 2014, Feb 2023 |
| T&T Scientific | , | Website gone May 2023 |
| 206 Ortho | , | Shut down 2021 |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| BioTeam | Middleton, MA | Scientific IT consulting |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| Activ Surgical | Boston, MA | Surgical Software |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| MedGyn Products | Westmont, IL | OBG Devices |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Corza Medical | Shanghai, China | Surgical Devices |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| Epigenos Biosciences | , | |
| IR2Dx | , | Gone, 2019 |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| , | Pandemic era government spongers | |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Indena | Milan, Italy | CDMO |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments, ADCs |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| , | Renamed Helus Pharma, Jan 2026 | |
| Medicure | Princeton, NJ | Small Molecule |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Procos | Cameri, Italy | Contract Manufacturing |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| Xenikos | , | Shut down early 2023 |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| , | No news 2017 - Apr 2026 | |
| Evofem Biosciences | San Diego, CA | Women's health |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Createrna Science | Shanghai, China | Small Molecules |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| BBOT | South SF, CA | RAS-targeted small molecules |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| Proteome Sciences | Surrey, UK | Proteomics |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Astrum | Paris, France | Clinical Development CRO |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| , | Website down Feb 2026 - Jul 2026 | |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| , | Website down Sep 2025 - Feb 2026 | |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| ACROBiosystems | Zug, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| Zai Lab | South SF, CA | Small Molecules |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| miR Scientific | , | Renamed miRNA Scientific |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Serentis | , | Website Gone |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| Synedgen | Claremont, CA | Biofilm Control |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| VentriFlo | Pelham, NH | Blood Pumping System |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| MYcroarray | , | Renamed Arbor Biosciences |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| XellSmart | Shanghai, China | Cell Therapy |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| CanBas | Shizuoka, Japan | Small Molecules |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Regenica Biosciences | , | Gone Nov 2020 |
| Lipid Genomics | , | Seems unserious |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| Revotek | , | Website down May 2023 - Sep 2023 |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Pangea Pharmaceuticals | Brielle, NJ | Generics, B2 |
| Gastrotech | , | Now Rose Pharma |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Medion Diagnostics | , | Bought by Grifols? |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| Roswell Biotechnologies | , | Shut down late 2022 |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| General Oncology | Brookline, MA | Cancer Therapies |
| Molecular Detection Inc | , | Gone 2016 |
| Amplified Proteomics | , | Shut down Jan 2006 |
| Velquest | , | Bought by Accelrys Jan 2012 |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| , | Renamed ScionxBio | |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Gene Signal | , | Bankrupt, Apr 2021 |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Cira Discovery | , | Website copyright 2003 |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| SERB Pharmaceuticals | Hattiesburg, MS | Specialty pharma developing, manufacturing - rare diseases, rare emergency medicine, medical countermeasures. |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| G1 Therapeutics | , | |
| Avioq | Durham, NC | HIV Diagnostics |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| Athlon Pharma | , | No news since 2006 lawsuit |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Gilead | Foster City, CA | Small Molecules |
| ScionxBio | Tel Aviv, Israel | Extended-release RNA |
| Actylis | Port Washington, NY | Raw Materials |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Santen | Osaka, Japan | Ophthalmics |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Amoytop Biotech | Xiamen, China | Biologics |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| DKP Genomics | , | Dissolved Jul 2025 |
| , | Website down Jul 2025 - Dec 2025 | |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| Creative Bioinformatics Consultants | , | Gone |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| , | Website down Oct 2025 - Feb 2026 | |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Amadix | Valladolid, Spain | Diagnostic development |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Proimmune | Oxford, UK | Immunology research products |
| NeoVista | , | Gone 2011 |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| ActivaTek | , | Acquired by North Coast Medical |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| Piramal | Ahmedabad, India | CDMO |
| , | Website down Jan 2026 - May 2026 | |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Codon Devices | , | Closed Apr 2009 |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Maroon Biotech | , | Gone Sep 2010 |
| Piramal | Turbhe, India | CDMO |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Elona Pharmaceuticals | , | Gone |
| Rosedale Medical | , | Now Intuity Medical |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| , | Filings late Jul 2022 - Jun 2026 | |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| SironRx | , | Website gone Jul 2015 |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Proteom | , | Acquired by Amura Ltd |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| ImmunGene | , | Merged into new company, Apr 2019 |
| , | Shut down Feb 2026 | |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Grunenthal | Aachen, Germany | Small molecules |
| ARC Medical | , | Acquired by Typenex Medical |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| Protein Polymer Technologies | , | Basically Gone |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| CertiRx | , | Shut down |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Nanovelos | , | Subsumed into Nanogroup |
| StemBioSys | San Antonio, TX | Stem Cells |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| STARLIMS | Hollywood, FL | LIMS |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| , | Selling pipeline, winding down Jul 2025 | |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| FyoniBio | Berlin, Germany | Cell Line development, process development, analytical services |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| Teva | Toronto, ON | Small Molecules |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Lannett | Trevose, PA | Generic Small Molecules |
| Novotech | Shanghai, China | Clinical Research |
| Invibio | Cleveleys, UK | Implants |
| Theranos | , | Dissolving, Sep 2018 |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Syneos Health | Newtown, PA | Clinical Development |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| iuvo | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| CMD Medtech | Columbus, OH | Medical Device Development |
| AerovectRx | , | No news since 2006, Website gone |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Divide and Conquer | , | Website gone Mar 2024 |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Root Lines Technology | , | Renamed Samabriva |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| Pathnostics | Irvine, CA | Diagnostics |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| CMP Pharma | Farmville, NC | Small Molecules |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Viatris (2) | Hyderabad, India | Small Molecules |
| Avineuro | , | Website taken over Feb 2024 |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| Ascelegen | , | Closed |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Sanofi | Haverhill, UK | Small Molecules |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| XDx | , | Changed name to CareDx |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| , | Acquired by Hologic, Jan 2025, $350M | |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Advaned Viral Research | , | Shut down 2009 |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| RION | Rochester, MN | Exosome Therapeutics |
| CultureTrax | , | Shut Down Dec 2019 |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Delpharm | Evreux, France | Contract Manufacturing |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| InVasc Therapeutics | , | Shut down 2012 |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Acylin Therapeutics | , | Assets sold 2014 |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| Vectura | , | |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| , | Website down Jan 2026 - May 2026 | |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Boston Biokeys | , | Gone June 2017 |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Unigene Laboratories | , | Closed 2013 |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| , | Renamed Peritia, Jan 2026 | |
| KAI Research | , | Acquired by Navitas Life Sciences |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| GenoSpace | Boston, MA | Platform for genomic data |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| , | Acquired by QOL Medical, Nov 2025 | |
| Crown Bioscience | Beijing, China | Drug Development |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| , | Shut down Jun 2026 | |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Otsuka | Tokushima, Japan | Small Molecules |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| Maxwell Biosciences | Austin, TX | Antivirals |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| Mentrik Biotech | , | Gone |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| Quiescence Technologies | , | Website Gone |
| Celsense | , | Shut down Dec 2021 |
| Scios | , | Bought by JnJ, Feb 2003 |
| Vitrology | , | Acquired by SGS, May 2012 |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| DanPET | , | One guy, Feb 2024 |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| Anavex Life Sciences | New York, NY | Small Molecules |
| TamuroBio | , | Shut Down Jun 2024 |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| , | Acquired by Artis Biosolutions, Apr 2025 | |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| Biocorp | Issoire, France | Medical Devices |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| NB Therapeutics | , | Gone |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Barrier Therapeutics | , | Bought by Stiefel |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| DM Clinical Research | Houston, TX | Clinical Research |
| , | Pivoted to crypto Jan 2026 | |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| Zumutor Biologics | Bangalore, India | Biologics |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| , | Website down Jul 2025 - Oct 2025 | |
| , | Gone Aug 2026; LI gone Jul 2026; Website down May 2026 - Jul 2026 | |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| , | Website down Jan 2026 - May 2026 | |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| Stago | Tianjin, China | Diagnostics |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Arstasis | , | Appears Gone Sep 2017 |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| , | Renamed Kapadi, Nov 2025 | |
| Qrativ | , | Folded into nFerence |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| VastBiome | , | Renamed PragmaBiome |
| Libra Clinical Research Associates | , | Gone |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| NanoSort | , | Renamed NanoCellect |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Celemics | , | Gone Jul 2018 |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| Accellacare | Salisbury, NC | Clinical Research |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| , | Website down Oct 2025 - Feb 2026 | |
| ZyGEM | , | Renamed MicroGEM |
| Sicor Biotech | , | Bought by Teva 2004 |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Beta-Pro | , | Now Triangle Research Labs |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| , | Merged with crypto company, Dec 2025 | |
| , | Pivoted to crypto, Apr 2026 | |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| Cygene Labs | , | Gone |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| ApoImmune | , | Gone 2014 |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| PredxBio | Pittsburgh, PA | Image Analysis |
| , | Website down Jul 2025 - Jan 2026 | |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Curadigm | , | folded into Nanobiotix |
| , | Website down Jul 2025 - Oct 2025 | |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| iTherapeutics | , | Doubt they do anything |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Karykion | , | Website outdated, doesn't seem serious |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Obecure | , | Inactive, no info |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| Glialogix | , | Gone Nov 2017 |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| Diversa | , | Merged with Celunol to become Verenium |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| , | Winding down Jul 2026 | |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| X7 Research | , | Website hijacked Feb 2025 |
| , | Website down Oct 2025 - Jan 2026 | |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Weatherden | London, UK | Clinical Consulting |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Nteryx | , | Changed name to Ardelyx |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Tecomet | Lansing, MI | Forging, CNC Machining, EDM, Finishing, Special Processes |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Allievex | , | Shut down Feb 2025 |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| mibe Arzneimittel | Brehna, Germany | Generics |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| NeoTrail Therapeutics | , | |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Pharmion | , | Acquired by Celgene 2007 |
| BIND Biosciences | , | Now BIND Therapeutics |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| , | Website down Oct 2025 - Feb 2026 | |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| , | Website down Apr 2026 - Jun 2026 | |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| M2 Medical | , | Now Asante Solutions |
| Valsphere | , | Website gone Nov 2019 |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| , | Part of SBO Hearing, Feb 2026 | |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| Compugen | San Francisco, CA | Biologics |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| , | Website down Jun 2025 - Dec 2025 | |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Clinisys | Tucson, AZ | LIMS Platform |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Chiron | , | Bought by Novartis |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Peptimmune | , | Liquidated 2011 |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Ergomed | Surrey, UK | Clinical Research |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Trophea Development | , | Liquidated Dec 2019 |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| , | Acquired by Guard Therapeutics, Jun 2026 | |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Niowave | Lansing, MI | Radioisotopes |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Cytiva | Freiburg, Germany | Medical Devices |
| BG medicine | , | Gone 2019 |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| InxMed | Beijing, China | Oncology Treatments |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Orros Therapeutics | , | gone 2018 |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Belyntic | Berlin, Germany | Immunotherapies |
| Anesiva | , | Bankrupt 2010 |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| , | Renamed Faeth Therapeutics, Jun 2026 | |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| Epigene Labs | Paris, France | Data Integration Platform |
| |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Singulex | , | Shut down Jun 2019 |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| , | Website down Aug 2026; LI gone Nov 2023 | |
| AmCell Biosciences | , | Website gone Apr 2021 |
| Evogene | Rehovot, Israel | Computational Biology |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Leading Pharma | Fairfield, NJ | Generics |
| NanoVector | , | Gone 2019 |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| TamRx | , | Website taken over Aug 2020 |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| Octapharma | Lingolsheim, France | Plasma Products |
| , | Part of Evogene | |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| , | Assets being sold off May 2026 | |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| , | ||
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| Terumo Medical | Somerset, NJ | Medical Devices |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| PRACS Institute | , | Bankrupt 2013 |
| Boston Scientific | Cork, Ireland | Medical Devices |
| Virometix | Schlieren, Switzerland | Vaccines |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| Typharm | Norwich, UK | Generics |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Inference | Pune, India | Clinical Trial Services |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| Riboxx | Dresden, Germany | RNA Products |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Polytherapeutics | , | Gone Jun 2018 |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| , | No news 2019 - Sep 2025 | |
| RNA Therapeutics | , | No website Mar 2020 |
| DiaVax Biosciences | , | Renamed Helocyte |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| Artivila Biopharma | Shenzhen, China | Small Molecule Drugs |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| Atugen | , | Acquired by SR Pharma 2005 |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| BioWa | , | Part of Kyowa Kirin Group |
| XStalBio | , | Folded |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| InBios International | Seattle, WA | Clinical Diagnostics |
| GeneDx | Stamford, CT | Genetic Data |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Genovis | Cambridge, MA | Nanoparticles |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Menarini | Florence, Italy | Biologics |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| Nuvelution Pharma | , | Gone 2020 |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| , | Founder, Principal gone Sep 2024 | |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| |
Alderley Park, UK | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Erbe | Tübingen , Germany | Surgical Systems |
| , | Website down Aug 2025 - Dec 2025 | |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Savant HWP | , | Gone 2019 |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| , | Acquired by Stryker, Oct 2024 | |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Macleods Pharmaceuticals | Tembhode, India | Generics |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| iWel | Exton, PA | Glucose Meters |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Conkwest | , | Website gone Dec 2015 |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| Singer Instruments | Watchet, UK | Laboratory automation |
| DiaGenic | , | Switched to energy sector |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| , | Acquired by eurifins, Sep 2024 | |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| , | Website down Sep 2025 - Dec 2025 | |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| Viropro | , | Bankrupt 2015 |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| , | Website down May 2025 - Sep 2025 | |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Pharmaron | Ningbo, China | R&D Services |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Cam Med | , | Renamed Qlibrium |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Viva Biotech | Shanghai , China | Contract Research |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Revolution Biomanufacturing | Worcester, MA | mRNA, lipid nanoparticle CDMO |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Parexel | Harrow, UK | Clinical Research |
| BionX Medical | , | Acquired by Ottobock |
| COOL-BIO | , | Gone |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| QuantaBio | Beverly, MA | PCR equipment |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| , | Acquired by Canoa, Aug 2019 | |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| ICU Medical | San Clemente, CA | Disposable medical products |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Pevion Biotech | , | Gone, 2-19-14 |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| Prolexys Pharmaceuticals | , | Website Gone |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Healogix | Doylestown, PA | Consulting |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Picoseq | , | Renamed Depixus |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| , | Acquired by Edwards, Oct 2024 | |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| , | Renamed Edding, Feb 2026 | |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| BioChain | Newark, CA | Sample Preparation |
| Mastel Surgical | Schiller Park, IL | Surgical Devices |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Ipsen | Wrexham, UK | Biologics |
| Salus Bioscience | , | Forfeited in CA |
| EyeTel Imaging | , | Gone Jul 2015 |
| Signant Health | Horsham, PA | eClinical Solutions |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Sirius Genomics | , | Gone |
| Evoke Medical | , | Renamed DirectSync Surgical |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| SARcode | , | Bought by Shire Mar 2013 |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Pirche | Grünwald, Germany | Transplant Matching |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Originus | , | Gone |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| BeOne Medicines | Pennington, NJ | Small Molecules, Monoclonal Antibodies |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| , | Part of Greenpharma | |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Gilead | Edmonton, AB | Small Molecules |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Norac Pharma | Azusa, CA | API Manufacturing |
| Aztech Sciences | , | Website gone Jun 2021 |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| ChunLab | , | Renamed CJ Bioscience |
| Gensco Pharma | Doral, FL | Transdermals |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Glide Pharma | , | Renamed Glide Technologies |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| Antigenics LLC | , | Now Agenus |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Roxall | , | No news 2019 - May 2025 |
| Refeyn | Oxford , UK | Mass Photometry |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| , | Website down Mar 2026 - Aug 2026 | |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| CureBiotech | , | Presumed gone |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| Kinaxo | , | Bought by Evotec |
| Medarex | , | Bought by BMS 2009 |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| Adlyfe | , | Gone, no info |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Voitheia Bioscience | , | |
| Oncofactor | , | Gone 2016 |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Appia Bio | , | Shut down Aug 2025 |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Novartis Animal Health | , | Acquired by Lilly |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Evalve | , | Owned by Abbot Vascular |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Bionovis | Valinhos, Brazil | Biosimilars |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Simpirica Spine | , | Became Empirical Spine |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Harmony Labs | , | Now Ei |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| Translational Bioscience | , | |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| Zoll | Deerfield, WI | Medical Devices, Defibrillators |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Expression Patholgy | , | Now OncoPlexDx |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| FineHeart | Pessac, France | Heart Failure Device |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| NorthernBio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| RadioRx | , | Now EpicentRx |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| , | No news 2021 - Jun 2026 | |
| Groove Biopharma | , | Gone 2015 |
| , | Website down Feb 2026 - Jul 2026; filings Late Jun 2024 - Dec 2025 | |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| Pathway Genomics | , | Renamed OmeCare |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Wyeth | , | Bought by Pfizer |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Covaris | Woburn, MA | DNA Sample Prep |
| , | Website under construction Dec 2024 - May 2026 | |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| Elan | , | Bought by Perrigo, Dec 2013 |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Santen | Tampere, Finland | Ophthalmics |
| Abviva | , | Gone, 2008 |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Ergomed | Mumbai, India | Clinical Research |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| simAbs | Diepenbeek, Belgium | Fast, flexible and cost-effective biologics development and GMP manufacturing |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| , | Part of Genesis Biotechnology Group | |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| Kuroki Consulting | , | Shut down 2020 |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| , | LI gone Jul 2026; Website down May 2026 - Jul 2026; fka Mynosys Cellular Devices | |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| NuLife Sciences | , | Shell acquired for a security business |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Vista.ai | Palo Alto, CA | MRI Software |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| XellSmart | Suzhou, China | Cell Therapy |
| Heragen | , | Gone |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Procertus | , | Website Gone, Apr 2016 |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Gossamer Bio | San Diego, CA | Small Molecules |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| BioMAS | , | Ceased operating, Jul 2016 |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| PTM BioLabs | , | Renamed PTM BIO |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| American Biooptics | , | Renamed Avivo BioOptics |
| Lupin | Goa, India | Generics |
| , | Website down Mar 2026 - Aug 2026 | |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| TissUse | Berlin, Germany | Multi Organ chip |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| Purely Proteins | , | All employees gone, no info |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| Arginox Pharmaceuticals | , | Apparently Gone |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Anacura | Evergem, Belgium | Analytical |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Rinat | , | Bought by Pfizer 2006 |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| Lumen Bioscience | Seattle, WA | Biologics |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Provasculon | , | Website Gone, Apr 2014 |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Micrologix Biotech | , | Renamed Migenix |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Concordia Healthcare | , | Now Concordia International |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Xention | , | All programs halted or disposed of by 2016 |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| , | Renamed Until Labs, Oct 2025 | |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| Nycomed | , | Acquired by Takeda 2011 |
| Novotech | Bangkok, Thailand | Clinical Research |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Neose | , | Gone |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Paranta Biosciences | , | Website gone Dec 2021 |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| , | Website down Sep 2025 - Feb 2026 | |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Aracea Therapeutics | , | No website Aug 2022 |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| HawkCell | Lyon, France | MRI Research Technology |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Alfama | , | Merged into Proterris, May 2017 |
| , | Website down Aug 2025 - Jan 2026 | |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Synostics | , | Gone 2014 |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| Axya medical | , | Gone 2012 |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Website down Feb 2026 - Aug 2026 | |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| |
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| Cellanome | Foster City, CA | Multiomics Platform |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Apollo Spine | , | Renamed G6 Spine |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Parcell Labs | , | Website Gone, Oct 2016 |
| NIOX | Oxford, UK | Asthma management device |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| Compucyte | , | Sold Assets to Thor Labs |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| , | Acquired by Ensysce Biosciences, Aug 2026 | |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| Proveri | , | Gone 2016 |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| OperaCRO | , | Now part of Tigermed |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| , | Website down Jul 2025 - Dec 2025 | |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Rx3 | , | Now Trius Therapeutics |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| , | Website down Feb 2026 - Jul 2026 | |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Summit Therapeutics | Palo Alto, CA | Utrophin modulation technology |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Diverse Genomics | , | Website gone Jul 2020 |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| XtalPi | Beijing, China | AI Drug Design |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| DiagnoSearch | Thane, India | Clinical Research |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Sanovel | Silivri, Turkey | Generics |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| , | Acquire by Savillex, Nov 2024 | |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| HiMedia Laboratories | Thane, India | Microbiology Products |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| Avatar Medical | Paris, France | Surgical Visualization |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Clarapath | Hawthorne, NY | Pathology Device |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| Rallybio | New Haven, CT | Therapeutics |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Pharmaron | Beijing, China | R&D Services |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Quellthera | , | Subsumed into Liveleaf |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| InnovAAVector | Pozzuoli, Italy | AAV CDMO |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Omeros | Seattle, WA | Small Molecules |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| DynoSense | , | Shut down Sep 2022 |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| Klogene Therapeutics | , | Gone 2019? |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| Instylla | Bedford, MA | Embolization treatment |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| XenaCare | , | Gone |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| CNS Research | , | Seem gone, 2020 |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Mologen | , | Liquidating, May 2020 |
| , | No news 2018 - Jul 2026 | |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| CATO SMS | , | Renamed Allucent, May 2022 |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| NeuExcell Therapeutics | King of Prussia, PA | Gene Therapy for Neural Regeneration & Repair |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Pierce | , | Part of Thermo Fisher |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Phytomedics | , | Can't find info on it |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| OvaGene Oncology | , | Gone Feb 2020 |
| Bioenza | , | Website gone Sep 2017 |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| , | Website down Oct 2025 - Feb 2026 | |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| TeutoCell | , | Renamed Xell, 2014 |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| , | being Acquired by Chugai, Oct 2025 | |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Talis Biomedical | , | |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| AllerMAbs | , | Website gone Oct 2022 |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Prokarium | London, UK | Oral Vaccines |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| SHY Therapeutics | Valhalla, NY | ATP/GTPase Modulating Small Molecules |
| , | Renamed Pixl.bio, Nov 2025 | |
| Novonesis | Beijing, China | Enzymes |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| VasoNova | , | Acquired by Teleflex Medical |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| Synaptiq Therapeutics | ZZ, Iceland | |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Zai Lab | Shanghai, China | Small Molecules |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Endocare | , | Website down Jan 2021 - May 2021 |
| VGX Pharmaceuticals | , | Merged with Inovio |
| Molecular Sensing | , | Business revoked Aug 2019 |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| , | Nothing happening Aug 2026 | |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Vivifi Life Sciences | Bangalore, India | Generics |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Proxima | New York, NY | AI Protein Folding Platform |
| , | Website down Jan 2026 - May 2026 | |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| NinePoint Medical | , | Seems gone Sep 2020 |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| Invivyd | New Haven, CT | Therapeutic Antibodies |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| Chrysalis | Burlington, MA | GMP Space |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| , | Seems inactive Jan 2026 | |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Tecomet | Holt, MI | Additive Manufacturing, Forging - Orthopedics |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| , | Website down Nov 2025 - Apr 2026 | |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Advansta | San Jose, CA | Protein characterization products |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Novacea | , | Bought by Transcept |
| EmpathBio | , | |
| Calzada | , | Renamed Polynovo |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Scion Medical Technologies | , | Gone 2016 |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Flow Eighteen38 | , | |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Isis Biopolymer | , | Website taken over |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics, CDMO |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| , | Acquired by Sebia, Dec 2022 | |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| Ionian Technologies | , | Gone Mar 2016 |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| , | Shut down Feb 2026 | |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Cureport | Worcester, MA | Nanomedicines |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| , | ||
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| , | Acquired by EPI, Mar 2022 | |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Virvio | , | Gone Feb 2020 |
| |
Lyon, France | Evotec is a multinational CRO/CDMO providing integrated drug discovery, development and manufacturing services. It combines target discovery, medicinal chemistry, biology, ADME-Tox, translational sciences, biologics development and GMP manufacturing within a single integrated organization. |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| , | Website down Jul 2025 - Dec 2025 | |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| BioLegacy Research | San Diego, CA | Contract Research |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| ArgusEye | Linköping, Sweden | Biosensors |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| Steba Biotech | , | Renamed ImPact Biotech |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Biovays | , | Website Gone |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| August Therapeutics | , | Shut down Dec 2024 |
| Anvyl | , | Website gone Jan 2021 |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Apollomics | Foster City, CA | Cancer medicines |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Cell Genesys | , | Merged with BioSante |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| OxyPharma | , | Website not updated in five years, emails bounced |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Alcon | Mississauga, ON | Eye Care Products |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| Velos | , | Acquired by WCG, Mar 2018 |
| BioParadox | , | Shut down Dec 2017 |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| Deinove | , | Bankrupt Mar 2023 |
| 76Bio | , | Shut down Jan 2025 |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| CellASIC | , | Bought by Millipore, May 2012 |
| Ileo Science | , | Seems gone Mar 2022 |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| SteriTech | Surrey, UK | Process Equipment |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Ampac Analytical | , | part of SK pharmteco |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| , | Acquired by Quest, Jun 2023, $450M; aka Haystack Oncology | |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| Resilience | Hamilton, OH | Biomanufacturing |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Qynapse | Paris, France | Imaging Analysis |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| Quantificare | Biot, France | Medical Imaging |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Mabqi | Grabels, France | Antibody Discovery |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Alerchek | , | Closed late 2016 |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Kivu Bioscience | San Francisco, CA | ADCs |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| , | No news 2021 - Jun 2026 | |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| NeuroWave Systems | Beachwood, OH | EEG |
| GeneSeek | , | Bought by Neogen |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| IBA Analytics | , | Website gone Jul 2015 |
| Conformis | , | |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| AliveDx | Eysins, Switzerland | Diagnostics |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Hua Medicine | Shanghai, China | Small Molecules |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Getinge | Hechingen, Germany | Medical Technology |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| Orphan Therapeutics | , | Gone Mar 2010 |
| , | Exosomes for neurodegenerative | |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Tarpon Biosystems | , | Gone by 2017 |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| MeDiNova Research | , | Now part of Accelacare |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| , | Renamed THX Pharma, Sep 2025 | |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Corin | Cirencester , UK | Orthopedics |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Pharmascience | Montréal, QC | Generics |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| DNAe | London, UK | Next-gen Sequencing |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| Selventa | , | Closed 2016 |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| Anoixis | Natick, MA | Pharmacometric Services |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| AntiOp | , | Tech sold Jun 2015 |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| PredictImmune | , | Shut down Nov 2023 |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| Regulome | , | Gone 2006 |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Boston Neurosciences | , | Website down Jun 2020 |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Piramal | Ennore, India | CDMO |
| Medley Genomics | , | Website for sale Feb 2021 |
| , | Renamed TransformaBio, Jul 2026 | |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Enlibrium | , | Gone 2018 |
| Prognosys Bioscience | , | 10 years in stealth mode |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| , | Acquired by Lonza, Jun 2023 | |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| Nanostream | , | Closed Mar 2008 |
| Opticyte | Seattle, WA | Cellular Oximetry |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Koelis | Meylan, France | Prostate Biopsy System |
| , | Website down Feb 2026 - Jul 2026 | |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| , | Website down Feb 2026 - Jul 2026 | |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| CP Life Science | , | Split and became Medvacon |
| Formex | , | Merged into BioDuro, Nov 2015 |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| , | Website down Feb 2026 - Aug 2026 | |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| StaphOff Biotech | , | Shut down 2017 |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| Bioprosthetics | Newark, DE | 3D-printed bone grafts, skin grafts, and eye lenses |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| Kona Medical | , | Closed, Dec 2016 |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| EnquBio | San Diego, CA | Contract Research & Services |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| Plureon | , | Website gone, one employee after 17 years |
| Affigen | , | Liquidating Fall 2019 |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Stelvio Oncology | , | Gone late 2019 |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| CohBar | , | Shut down, late 2023 |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| PsiOxus Therapeutics | , | |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| , | ||
| tte laboratories | , | Acquired by Transcat |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website under construction Nov 2025 - Jul 2026 | |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| CorTechs Labs | , | Renamed Cortechs.ai |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| DyNAbind | , | Shut down Apr 2025 |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Mojave Therapeutics | , | Gone |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Celerion | West Conshohocken, PA | Clinical Research |
| Arna Pharma | Sydney, Australia | Generics |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| TransGenRx | , | Bankrupt |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Purinomia Biotech | , | |
| , | Website down Sep 2025 - Feb 2026 | |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Pharmatrope | , | Absurd website 2020-2023 |
| , | Acquired by Novacyt Group | |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| Telis Bioscience | , | Renamed Alvea |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Supeira | , | Website gone Mar 2023 |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Verséa Health | Tampa, FL | Diagnostics |
| Core Biomedicine | Allston, MA | |
| Biomatters | , | Renamed Geneious |
| |
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| EXO Biologics | Liège, Belgium | Exosomes |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| Adroit Surgical | , | Defunct |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Vivamer | , | Shut down, Jul 2015 |
| Wacker | Jena, Germany | Biologics CDMO |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| Oncovista | , | Dormant 2016 |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| Rezo Therapeutics | San Francisco, CA | |
| Elypta | Solna, Sweden | Liquid Biopsy |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| , | Website down Feb 2026 - Jul 2026; Linkedin gone Jul 2026 | |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| CardioEphEx | , | Shut down Dec 2020 |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| MicrofluidX | , | Renamed MFX |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| A&O Pharma | Efringen-Kirchen, Germany | Regulatory & Analytical Consulting |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| , | business filings late Oct 2023 - Oct 2025 | |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| Pharmos | , | Gone |
| , | LI gone Jul 2026; Filings late Nov 2023 - Jul 2026; fka Gala Therapeutics | |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Niche Generics | Hitchin, UK | Contract Generics |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| StemPar Sciences | , | Website disappeared, no news |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| Signatur Biosciences | London, UK | PCR Platform |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| , | Website down Jul 2025 - Dec 2025 | |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| ApoVax | , | Shut down Jul 2014 |
| Rafagen | , | Website redirecting to Rophibio |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Pangenetics | , | Bought by Abbott |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Pfizer | Ringaskiddy, Ireland | API production |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| Actera Pharmaceuticals | , | Closed |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| MedShape | , | Acquired by DJO, Apr 2021 |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| , | Acquired by MMS, Feb 2025 | |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| , | Liquidating Jan 2026 | |
| Syngene International | Bangalore, India | Contract Research |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Nucleus Network | Herston, Australia | Clinical Research |
| Iquity Labs | , | Merged into Decode Health |
| Almirall | Barcelona, Spain | Small Molecules |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Intelliseq | Kraków, Poland | Genome Informatics |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| Bluestar Genomics | , | Renamed ClearNote Health |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| , | Website down Oct 2025 - Feb 2026 | |
| Cytiva | Marlborough, MA | Medical Devices |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| Keenova | Bridgewater, NJ | Small Molecules |
| OBDURO Biotechnologies | , | never a registered CA business |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Diamed | , | Bought by Bio-rad |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Omniseq | , | Acquired by LabCorp, 2021 |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| , | Website down Apr 2026 - Aug 2026 | |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| Helsinn | Iselin, NJ | Small Molecules |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| Torpedo Bio | , | |
| Sonavex | Baltimore, MD | Ultrasound |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Cellcion | , | Website gone, company going inactive |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| Kallyope | New York, NY | Gut-brain axis focus |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Maccine | , | Gone |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| PL Developments | , | Parts of website taken over |
| , | Acquired by Alcon, Sep 2025 | |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| Scholar Rock | Cambridge, MA | Biologics |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Cytely | Lund, Sweden | Automated Assays and Workflows |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Redoxis | Lund, Sweden | Drug development CRO |
| Catylix | , | Shut down Oct 2021 |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| NovaLead Pharma | Pune, India | Small Molecules |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Accellacare | Ames, IA | Clinical Research |
| Nuevolution | , | Bought by Amgen May 2019 |
| Coeptis | , | |
| , | Website taken over, Jul 2026 | |
| Bone's Technology | Hong Kong, China | Bone Density Analysis, Surgical Planning |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| Venta Medical | , | Gone, Apr 2017 |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| AMDL | , | Now Radient Pharmaceuticals |
| ProCrysta Biologix | , | Shut down 2018 |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| Diex Recherche | Sherbrooke, QC | Clinical Site |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| , | Acquired by Sanofi, Jul 2025, $9.1B | |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| BinaryBio | , | Out of business Jul 2015 |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| CisThera | , | Shut down Jan 2023 |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| , | Linkedin gone Jul 2026; Website down Mar 2026 - Jul 2026; Not positive on drug types | |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| , | Website down Jul 2025 - Jan 2026 | |
| , | Website down Dec 2025 - Jun 2026 | |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| VERAXA Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| BioDatomics | , | Website gone Jan 2019 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Metabasis | , | Bought by Ligand |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| SmartCells | , | Bought by Merck Dec 2010 |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Almac | Craigavon, UK | Pharmaceutical Services |
| , | Acquired by HB Fuller, Jul 2023 | |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| NeuroVasx | , | No website May 2019, founded 1997 |
| Hydra Biosciences | , | Website gone Mar 2019 |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| TE Connectivity | Berwyn, PA | Medical Devices |
| , | Website down Jan 2026 - May 2026 | |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| Clinnex | Ahmedabad, India | Clinical Research |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| ABgene | , | Bought by Apogent, Dec 2001 |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| , | Website down Nov 2025 - Mar 2026 | |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Omixon | Boston, MA | Next-gen sequencing products |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| Epigenesis Pharmaceuticals | , | Gone |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| Gataca | , | Gone |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| MedCision | , | Assets bought by MedCision, May 2018 |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| GeneoDx | , | Website gone Oct 2019 |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Twistnostics | , | Renamed Scanogen |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Asarina Pharma | , | Winding down Jul 2024 |
| Talee Bio | , | Renamed Spirovant Sciences |
| Getinge | Fairfield , NJ | Medical Technology |
| MetaMorphix | , | Changed to Scidera Genomics |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Nexus Spine | Salt Lake City, UT | Spinal Implants |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| CombImmune | , | Website Gone Jul 2015 |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| hVIVO | London, UK | Viral Services |
| GliaGen | , | Renamed CaCy Therapeutics |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Nesch, LLC | , | Website gone Oct 2018 |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Life Analytics Group | , | Gone |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| Java Clinical | , | Website gone Jun 2019 |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| WntResearch | , | Shell acquired by Opsy |
| Ezose Sciences | , | Rebranded as S-bio |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| Memento Medicines | , | |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| Alltrna | Cambridge, MA | tRNA therapies |
| Cellf BIO | , | Website taken over Jan 2019 |
| SiliCycle | Québec, QC | Separation Technologies |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| Modular Bioscience | , | Seems gone Jun 2022 |
| TibaRay | Fremont, CA | Upright Proton Therapy |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroCyte Therapeutics | New Taipei, Taiwan | Scaffold-free 3D Cell Culture |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology, Small Molecules, Peptide-drug conjugate |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bestat Pharmaservices | Taipei, Taiwan | Clinical Consulting |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Handa Pharmaceuticals | Tainan City, Taiwan | Specialty pharmaceutical development - generic and 505(b)(2) |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Vacino Biotech | Taipei, China | Broad-spectrum vaccines, nucleic acid drug products and brain delivery technology |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Yung Shin Pharm | Taichung, Taiwan | Small Molecules, Generics |
| Zai Lab | Taipei, Taiwan | Small Molecules |