Taiwan - Biotech Companies - Career Pages
| Novaliq | Cambridge, MA | Drug Delivery |
| , | Renamed Eledon Pharmaceuticals, Jan 2021 | |
| Inimmune | Missoula, MT | Immunotherapeutics |
| , | ||
| , | Website down Dec 2023 - May 2024 | |
| , | ||
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| , | Bought by Perrigo, Dec 2013 | |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| , | Gone Oct 2023 | |
| , | Merged with VIMRx Pharmaceuticals, Dec 1996 | |
| Metrochem | Hyderabad , India | APIs |
| Alexion Pharmaceuticals | Baar, Switzerland | Biologics |
| , | Changed name to Surgical Specialties Corp Jun 2013 | |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| , | Acquired by Valeant, rebranded as Bausch Health | |
| Pathnostics | Irvine, CA | Diagnostics |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| , | Renamed Rain Oncology, Dec 2022 | |
| , | Website Gone | |
| , | CoMentis/Anvyl co-creation to work on a drugs, seems gone | |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| , | Now Aptalis | |
| , | Acquired by Cocrystal Pharma, May 2011 | |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| QUIBIM | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| , | Shut down Sep 2019 | |
| , | Gone 2019 | |
| , | Acquired by Quince Therapeutics, Oct 2023 | |
| , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 | |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| , | Seems to have failed to get investment, 2020 | |
| , | Bought by Pfizer 2011 | |
| , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 | |
| Avioq | Durham, NC | HIV Diagnostics |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| , | ||
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| , | Not registered business in UK; No website Sep 2021 - Jul 2024 | |
| Paramit | Penang, Malaysia | Medical Device and Life Science Instrument Product Development and Manufacturing |
| , | Bought by Charles River Labs, Mar 2014 | |
| , | Website gone Jun 2020 | |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 | |
| , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL | |
| EOM Pharmaceuticals | Montvale, NJ | Peptide-nucleic Acid Solutions |
| , | Assets acquired by Maxwell Biomedical, Dec 2022 | |
| , | Acquired by Watson Pharmaceuticals, May 2011, $562M | |
| Brii Biosciences | San Mateo, CA | Bringing medicines to Chinese market |
| , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock | |
| , | Acquired by Alexion, Sep 2000, $41M | |
| Sintaho Pharmaceuticals | Chongqing , China | API Manufacturing, ADC CDMO |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| CHARM Therapeutics | London, UK | AI Protein Folding Drug Discovery |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| , | No info, but believed inactive | |
| , | No info, probably gone | |
| , | Acquired by Tempus, Feb 2023, became Tempus Radiology | |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B | |
| NuAire | Plymouth, MN | Lab Equipment |
| , | Merged into Idorsia, Jun 2020 | |
| , | Renamed Axial Therapeutics, Nov 2020 | |
| Purposeful | Athens, Greece | Repurposing Compounds |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| , | Changed name to Scios, Mar 1992 | |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| , | ||
| Future Fields | Edmonton, AB | Contract Protein Research |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Rampart Bioscience | Monrovia, CA | Non-viral, durable gene therapy |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| , | No website, May 2020 - Nov 2023 | |
| , | Dissolved, Sep 2016 | |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Violet Therapeutics | Cambridge, | Connectome Drug Discovery |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| , | Website gone Sep 2019 - Aug 2021 | |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| , | Changed name to Nimbus Therapeutics, Mar 2015 | |
| GEROPHARM | Moscow , Russia | Large drug maker |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| , | Presumed gone | |
| , | Acquired by Covidien, Jul 2010, $2.6B | |
| Biosceptre | Cambridge, UK | Therapeutics & Diagnostics targeting nf-P2X7 |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| , | no updates since 2012 as of Jan 2019. Seems not so serious | |
| Norgine | Milan, Italy | Specialty Pharma |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| ChromaCode | Carlsbad, CA | Real-Time PCR Multiplexing |
| , | Company apparently still exists as of 2013 according to PA business registry, but no information | |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Vaxart | South SF, CA | Oral Vaccines |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| , | Website Gone | |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| , | Acquired by GSK, Dec 2006, $54.8M | |
| , | Merged into Recombinetics, Oct 2020 | |
| Roche | Basel, Switzerland | Small Molecules |
| , | Acquired by CSL, Nov 2006 | |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| , | Renamed Bactobio | |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| , | Amateurish looking | |
| , | Renamed Gylden Pharma, Oct 2024 | |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Ailex Pharmaceuticals | Lenexa, KS | Small Molecules |
| , | Acquired by Takeda Oct 2012 | |
| , | No longer active | |
| , | ||
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| GL Technologies | San Diego, CA | Calibration Services |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| , | Merged into Chemgenex, Apr 2004 | |
| , | Acquired by Thermo Fisher, May 2011, $3.5B | |
| , | Acquired by X-Chem, Jan 2021 | |
| , | Closed according to Google, Dec 2018 | |
| , | Acquired by Ethypharm | |
| , | Acquired by MLM Medical Labs | |
| , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology | |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| HCW Biologics | Miramar, FL | Immunotherapy |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| , | ||
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | ||
| , | Shut down Feb 2019 | |
| , | Products now with Accure Therapeutics | |
| , | Website gone Jan 2019 | |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
 |
Tyrone, PA | Grace Fine Chemical | U.S. Domestic CDMO offering process scaleup and commercialization of small molecule APIs, RSMs and intermediates. Network of 2 fully integrated sites with a world class analytical team offers an industry-leading flexible supply chain through the back integration of its intermediates. |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| , | Acquired by Panbela Therapeutics, Jun 2022 | |
| ArgusEye | Linköping, Sweden | Biosensors |
| DiabetOmics | Hillsboro, OR | Medical Diagnostics |
| , | Closed Dec 2017 | |
| , | Assets acquired by OncBioMune, Jun 2020 | |
| Dogodan Therapeutics | Westford, MA | Nucleic Acid Therapeutics |
| , | Website Gone, Sep 2015 | |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| , | Sole 'employee' would not confirm existence | |
| , | ||
| Caranx Medical | Paris, France | Surgical, Robot Imaging |
| , | Renamed Attune Medical | |
| , | Virtual, No progress Mar 2015 - Jul 2019 | |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| CeQur | Greenville, SC | Insulin pump |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| , | Website down Oct 2021 - Mar 2022 | |
| Syntach | Lund, Sweden | Cardiac Support System for Health Failure Patients |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| , | Acquired by eurofins, $50M | |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| , | Website gone Nov 2023; Strategic Alts, Apr 2023 | |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones | |
| , | Renamed TargetEx Biosciences | |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| , | Website hijacked Feb 2025 | |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| , | Changed name to Rezolute, Dec 2017 | |
| , | Changed name to Aldeyra Therapeutics, Mar 2014 | |
| , | Bought by Brace Pharma Capital Jan 2015 | |
| , | Shell company, Apr 2024 | |
| , | Renamed iosBio Pharma, Jan 2021 | |
| Scipio Bioscience | Paris, France | Single-cell Sequencing |
| , | Acquired Relief Therapeutics, Jun 2016, took name | |
| , | Merged with Aadi Bioscience, Aug 2021 | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Around since at least 2012, nothing but a single page Google Website | |
 |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| , | Acquired by GSK, Jan 2019, $5.1B | |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Aspira Women's Health | Austin, TX | Diagnostics |
| , | Reverse Merged with CardioVentures, Apr 2023 | |
| |
Curtis Bay, MD | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| , | Bankrupt | |
| , | Acquired by Novotech | |
| , | Shut down late 2022 | |
| , | Renamed Egetis Therapeutics, Dec 2020 | |
| AbbVie | Dublin, Ireland | Medical Devices |
| , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 | |
| , | Merged with inVentiv Health, May 2017, renamed Syneos Health | |
| , | Renamed Inhibitor Therapeutics, Aug 2019 | |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| , | Shut down according to Google 2019 | |
| Quanticate | Hitchin, UK | Clinical Research |
| , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax | |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Jiangsu Hillgene Biopharma | Suzhou, China | Cell Therapy Products & Services |
| , | Changed name to Spectral Medical, Dec 2014 | |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Forge Biologics | Grove City, OH | Biologics |
| , | Acquired by WuXi Apptec, Oct 2011 | |
| , | Acquired by Sysmex, May 2022 | |
| , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 | |
| , | Website Gone, Nov 2016 | |
| , | Bought by Roche, Dec 2014, $400M+$225M contingent | |
| , | ||
| , | ||
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| , | Shut down Nov 2018 | |
| , | Renamed EpiMedTechGlobal, Jun 2024 | |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| , | No info 2017-2022 | |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| , | Acquired by Promethera Biosciences, Apr 2018 | |
| , | Acquired by Nucleus Biologics, Aug 2019 | |
| , | ||
| , | Website gone Jun 2023 - Sep 2023 | |
 |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| , | Acquired by eurofins | |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| LENSAR | Orlando, FL | Cataract Laser |
| bioMerieux | Cambridge, MA | Diagnostics |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| , | ||
| , | Acquired by Bioduro, Mar 2018 | |
| , | ||
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| DFE Pharma | Goch, Germany | Excipients |
| , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 | |
| , | Liquid silk. Site gone | |
| , | Bought by ResMed, Jan 2016 | |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| , | Acquired by Tempus, Dec 2019 | |
| , | Website down Mar 2023 - Sep 2023; fka CereDx | |
| , | Assets purchase by BrainCool, Oct 2016 | |
| , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology | |
| , | ||
| Provid Pharma | Monmouth Junction, NJ | Contract Research |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| , | Appears defunct | |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| AUM BioTech | Philadelphia, PA | RNA-silencing Products |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| , | Website down Jul 2024 - Sep 2024 | |
| , | Bankrupt, 2003 | |
| Galapagos | Romainville, France | Drug & Antibody Therapy Discovery |
| Foxo | Minneapolis, MN | Epigenetic Biomarker Technology |
| , | Sold to Apricus Bio, Dec 2011 | |
| ClinDatrix | Irvine, CA | Clinical Research |
| , | Shut down Sep 2022 | |
| , | Rebranded as parent company's name - SK Biotek | |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 | |
| , | Acquired by Knight Therapeutics, Nov 2019 | |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| , | No activity since 2008 | |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| , | Renamed Trovis Pharmaceuticals, Feb 2011 | |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones | |
| , | Defaulted, sued by employees | |
| BioTheryX | San Diego, CA | Small Molecules |
| , | Founder gone, website five years stale Aug 2023 | |
| , | Acquired by Assertio, Apr 2023, $248M | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Laid off all employees, Dec 2022 | |
| , | Renamed Nuvaira | |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| , | Shut Down Jul 2024 | |
| , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences | |
| , | Acquired by Porsolt, Dec 2015 | |
| , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 | |
| Aenova | Latina, Italy | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| , | ||
| , | Gone | |
| , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond | |
| Exelixis | Alameda, CA | Small Molecules |
| , | Acquired by BASF, Jan 2013 | |
| , | Now eurofins Genomics | |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity | |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| , | Acquired by Richter, Oct 2010 | |
| MediciNova | La Jolla, CA | Small Molecules |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees | |
| , | Changed name to Rafael Pharmaceuticals, Jun 2017 | |
| , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Renamed Polynovo | |
| , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M | |
| , | Website gone Jan 2020, no employees on LinkedIn | |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences | |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| , | Bankrupt Mar 2023 | |
| , | Shell company, Jul 2019, $482k market cap | |
| , | Website gone, no info Nov 2019 | |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| , | Renamed BTS Research | |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| , | Gone 2020 | |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Fabbrica Italiana Sintetici | Vicenza, Italy | Contract Development & Manufacturing, Generics |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand | |
| Pharma Medica | Toronto, ON | Clinical Services |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| , | ||
| , | Bought by Shire, Jan 2016, $5.9B | |
| , | Renamed Scanogen | |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| Cureport | Worcester, MA | Nanomedicines |
| , | Acquired by Transcat | |
| , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 | |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| , | Shut down Oct 2024 | |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 | |
| , | Changed name to Upcyte, Jun 2015 | |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Pfizer | Sandwich, UK | APIs, Small Molecules |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| , | Bought by Medtronic, Aug 2016, $1.1B | |
| , | ||
| , | Website down Oct 2022 - Mar 2023 | |
| , | Gone, 2017 | |
| , | Acquired by Actavis, Jul 2005 | |
| Babson Diagnostics | Austin, TX | Diagnostic Blood Testing |
| , | Acquired by CytoDyn, Jul 2006 | |
| Cytoskeleton | Denver, CO | Research Products |
| , | Renamed Integrated Bioanalysis, Oct 2020 | |
| , | Assets sold 2014 | |
| , | Gone 2014 | |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| , | Acquire by Zimmer Biomet, Jun 2016, $1B | |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M | |
| DDi | Basel, Switzerland | Clinical Software |
| RheoSense | San Ramon, CA | Viscometers |
| , | Changed name to Iovance Biotherapeutics, Jun 2017 | |
| , | ||
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| , | ||
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| , | Part of Inflexion Point | |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| , | Shut down 2018 | |
| , | Now Bruker Spatial Genomics | |
| , | Bought by Celgene, Jun 2010, $2.9B | |
| , | Website down Jul 2021 - Feb 2022 | |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Qlucore | Lund, Sweden | Visualization Software |
| , | Acquired by Brooks, Jul 2011 | |
| Codexis | Redwood City, CA | Biocatalysts |
| , | Renamed Formation Biologics | |
| , | Website taken over Dec 2021 - Jan 2022 | |
| , | Now CymaBay Therapeutics | |
| , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock | |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Molteni Farmaceutici | Scandicci , Italy | Small Molecules, Drug Delivery |
| ESSA Pharma | Vancouver, BC | Small molecules for cancer |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| , | Shut down Jan 2024 | |
| , | Merged with MetabAxis | |
| , | Renamed Hillal Biotechnology, Mar 2023 | |
| , | Bankrupt, May 2016 | |
| , | Tech acquired by Centauri Therapeutics, Jan 2016 | |
 |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Acquired by Relmada Therapeutics, Dec 2013 | |
| Daiichi Sankyo | Rueil Malmaison, France | Small Molecules |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| , | Acquired by Shire, Aug 2015, $92M | |
| Exosome Diagnostics | Martinsried, Germany | Biofluid-based molecular diagnostic tests |
| , | Acquired by Varian Medical, Apr 2014 | |
| , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 | |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| Pharmathen | Amstelveen, Netherlands | Generics |
| , | Website down Feb 2023 - Apr 2023 | |
| , | Website only in Hebrew, Aug 2019, gone Aug 2021 | |
| , | Renamed Contineum Therapeutics, Dec 2023 | |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| , | Acquired by BD, Oct 2014 | |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Novelty Nobility | Seongnam, Korea | ADCs |
| , | Winding down Feb 2025 | |
| Owl Biomedical | Santa Barbara, CA | Microchip-based disposable cell sorting technology |
| , | Renamed Serpex Medical | |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Lightpoint Medical | Cambridge, MA | Surgical Imaging Technology |
| , | Bought by Pfizer 2008; fka Texas Biotechnology Corp | |
| , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage | |
| , | Merged with Novocell & CyThera to become ViaCyte in 2004 | |
| , | Out of business 2012 | |
| , | Website Gone | |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| , | Renamed Calidi Biotherapeutics, May 2018 | |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| , | Gone, 2016 | |
| , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 | |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Organogenesis | Canton, MA | Biologics |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| , | Renamed Interna TX, Sep 2024 | |
| , | Liquidated Aug 2024 | |
| Elutia | Richmond, CA | Drug-eluting biomatrix |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| , | Joined J&J 1959 | |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Accellacare | Knoxville, TN | Clinical Research |
| , | Seems inactive | |
| , | Shut down late 2022; fka Theon Therapeutics | |
| , | Now Graybug Vision | |
| Alcon | Irvine, CA | Eye-Care Products |
| , | Inactive Jun 2016 | |
| CNCure Biotech | Jeollanam, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| , | Closed 2013, according to Washington dept of revenue | |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| , | Gone | |
| Ipsen | Wrexham, UK | Biologics |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| , | Bought by Genewiz, Dec 2015 | |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| , | No updates since 2011 as of Feb 2021 | |
| , | Acquired by Boston Scientific, Feb 2022, $1.75B | |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Pentapharm | Basel, Switzerland | APIs |
| , | Website gone, sole employee with Agilent now | |
| , | Renamed Qlibrium | |
| FIRE1 | Dublin, Ireland | Heart Failure Implant, Belt & App |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| , | Shut down Mar 2024; Strategic Alts, Mar 2023 | |
| , | Website is now general information on Biosimilars in Brazil | |
| , | Renamed Flindr Therapeutics | |
 |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics | |
| SiCare Bio | Kapolei, HI | Nanotherapeutics |
| , | Renamed Phaedrus Pharmaceuticals, Sep 2002 | |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| High Purity New England | Smithfield, RI | Single use products, Additional distributed equipment |
| Spriaso | Salt Lake City, UT | Small Molecules |
| , | Bought by Charles River, Aug 2012 | |
| , | Renamed BioXXmed, stopped doing R&D | |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| , | Seems inactive Feb 2023 | |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| , | Acquired by Philips, Aug 2020, $275M | |
| SciGene | Santa Clara, CA | Imaging sample prep |
| , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics | |
| , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 | |
| Sundia | Shanghai, China | Discovery & Development Services |
| , | Winding Down | |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Pfizer | Sollentuna, Sweden | Small Molecules, Biologics, Vaccines |
| , | Website Down Jan 2022 - Jul 2022 | |
| , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 | |
| , | Acquired by Shire, Aug 2010 | |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| , | ||
| , | Website down Feb 2021 - Sep 2021 | |
| AbbVie | Wyandotte, MI | APIs |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| , | Shell Company | |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| , | Acquired by Pacific Biosciences, Aug 2021 | |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| , | Assets Apparently Acquired | |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Part of Sandoz | |
| , | Gone 2003 | |
| , | Website from 2008 as of Mar 2019 | |
| Quantificare | Maringa, Brazil | Medical Imaging |
| , | Founder has another job, no employees listed on website | |
| , | Acquired by BioVentrix, Jan 2022 | |
| , | Employees all gone, Mar 2018 | |
| , | Most employees moved to InnerPulse | |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| , | Acquired by Mallinckrodt, Feb 2018 | |
| NeuroQure | Coto de Caza, CA | Gene Therapy for Neurological Disorders |
| Sebra | Tucson, AZ | Tube Sealer |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| , | ||
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| , | Bought by Pfizer | |
| , | No information | |
| , | Website gone Nov 2018 | |
| , | Bought by Abbott, Jul 2013, $310M | |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| , | Gone 2012 | |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| JLP Health | Vienna, Austria | Structural Biology by Genetics Platform |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones | |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| , | Renamed Advion Biosciences | |
| , | Bankrupt Jun 2022 | |
| , | Shut down May 2024 | |
| , | Website gone, Feb 2017, Presumed Defunct | |
| , | Website not working, redirecting strangely | |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| , | Website gone, Aug 2019 - Dec 2020 | |
| , | Changed name to Repros Therapeutics in 2006 | |
| , | Acquired by IQVIA, Oct 2017 | |
| , | Acquired by Vector Laboratories, Jul 2023 | |
| , | ||
| , | Acquired by Quris-AI, Oct 2024 | |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Integra LifeSciences | Boston, MA | Medical Devices |
| , | No news 2020 - Feb 2025 | |
| , | Acquired by Roche, Jan 2015, €120M + €350 milestones | |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| , | Gone? | |
| , | Not registered in MN, all employees gone Aug 2022 | |
| , | Acquired by AcelRx Pharmaceuticals, Jan 2022 | |
| Proteintech | Rosemont, IL | Research Antibodies |
| HOOKIPA Pharma | Vienna, Austria | Immunotherapies & vaccines |
| , | Gone Feb 2008 | |
| Evolution Biologyx | Center Valley, PA | Wound healing and the replacement and supplementation of damaged tissue |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| , | ||
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| , | Renamed Nektar Therapeutics | |
| , | No site, no news since 2006 as of Jan 2019 | |
| LEADS BioLabs | Nanjing, China | Monoclonal & Bispecific Antibodies |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| , | Gone Jan 2009 | |
| Bafna | Chennai, India | Generics |
| , | Website down Jan 2018-Feb 2019 | |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| , | Assets acquired by Pearson, Aug 2013 | |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| , | Website gone Sep 2020; Not registered as CA business, Mar 2020 | |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| , | Website gone Jun 2022 | |
| NeuraSignal | Los Angeles, CA | Robotically Assisted Ultrasound System for Brain Health Assessment |
| DNASTAR | Madison, WI | Molecular Biology Software |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| , | Acquired by Smiths Medical, May 2020 | |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Syneos Health | Morrisville, NC | Clinical Development |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| , | Now known as Prytime Medical | |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| , | Renamed Fabric Genomics, Mar 2017 | |
| Ikena Oncology | Boston, MA | Immuno-Oncology |
| , | Renamed Glide Technologies | |
| BioEclipse Therapeutics | Mountain View, CA | Immuno-Oncology |
| , | Renamed Kyverna Therapeutics, Oct 2019 | |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| , | Merged with Cartesian Therapeutics, Nov 2023 | |
| , | Renamed Modalis Therapeutics, Sep 2019 | |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| , | Bought by Rules-Based Medicine | |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones | |
| , | Closed Aug 2011 | |
| , | never a registered CA business | |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Shut Down, Dec 2018 | |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| , | Changed name to Adello Biologics, Sep 2016 | |
| , | Website down Sep 2022 - Feb 2023 | |
| , | ||
| Durham, NC | Website down Dec 2023 - May 2024 | |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| , | Bought by Yourgene Health, Apr 2019 | |
| MatTek | Ashland, MA | Cell Products, Services |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| , | Acquired by Mast Therapeutics, Apr 2014 | |
| , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 | |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Oticon | Smørum, Denmark | Hearing Aids |
| , | Acquired by SAFC | |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Xeris Biopharma | Chicago, IL | Injectables |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| , | Acquired by WCG, Mar 2018 | |
| , | Acquired by Evotec, Jan 2013 | |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad | |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| , | Acquired by Rubicon Research, Jan 2020 | |
| , | Bought by Teva, Mar 2008, $360M | |
| Ergomed | Raleigh, NC | Clinical Research |
| , | Acquired by UCB 2006 | |
| Minghui Pharmaceutical | Shanghai, China | Therapeutics |
| , | Renamed TME Pharma, Jun 2022 | |
| , | Shut down 2024? | |
| , | Acquired by Aytu Bioscience, Feb 2020 | |
| , | ||
| Piramal | Riverview, MI | APIS |
| , | ||
| , | Acquired by Aceto, Jun 2021 | |
 |
Taipei, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics | |
| , | Renamed Harness Therapeutics, Sep 2023 | |
| , | Acquired by Ferring, Apr 2018 | |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| , | Website Down May 2024 - Nov 2024 | |
| , | Renamed NanoDx, Apr 2020 | |
| EMD Serono | Boston, MA | Biologics |
| , | ||
| , | Renamed LumaBridge | |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| DNAe | London, UK | Next-gen Sequencing |
| , | Acquired by Abbott 2006 | |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| , | Closed 2016, CEO confirmed they decided to shut down | |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| , | ||
| , | Acquired by Opko Health | |
| , | Acquired by Takeda, Feb 2017, $5.2B | |
| , | Gone 2007 | |
| Activ Surgical | Boston, MA | Surgical Software |
| , | Website down Aug 2023 - May 2024 | |
 |
Shanghai, China | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Bought by Bristol-Myers, 1986 | |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| , | ||
| Metrohm | Mississauga, ON | Lab Data Management Software |
| , | Dissolved, Dec 2014 | |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 | |
| Altasciences | Everett, WA | Contract Research |
| , | Acquired by Menarini, Sep 2013 | |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| , | Website gone Oct 2019 - Dec 2019 | |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| , | Bought by AtriCure $99M, Oct 2015 | |
| Accellacare | Salisbury, NC | Clinical Research |
| , | Website gone Aug 2023 - Dec 2023 | |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Procos | Cameri, Italy | Contract Manufacturing |
| , | Bankrupt 2008 | |
| , | Renamed Abionyx, Aug 2019 | |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| , | Changed name to Caladrius Biosciences Jun 2015 | |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| Formulatrix | Bedford, MA | Lab Automation |
| Lymphobank | Besançon , France | Research Blood Products |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| , | Closed Apr 2009 | |
| , | Acquired by Cambrex, Nov 2022 | |
| , | Acquired by Microbiologics, 2017 | |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| , | Gone 2016 | |
| , | Website taken over Sep 2021 - Jan 2022 | |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| , | Bankrupt 2015 | |
| , | ||
| , | Renamed Acurex Biosciences | |
| GSK | Warren, NJ | Small Molecules, Vaccines, Biologics |
| , | Bought by Horizon Pharma Mar 2015 $1.1B | |
| , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M | |
| , | Acquired by Neuro-Hitech, Nov 2008 | |
 |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Renamed Aragen Life Sciences | |
| Cala Health | San Mateo, CA | Neurological Device |
| , | As of Feb 2018, Website still lists CEO who left in 2014 | |
| , | Acquired by Teleflex, Oct 2023, $600M | |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| Fios Genomics | Edinburgh, UK | Bioinformatics Data Analysis |
| , | Changed name to Commence Bio, Jan 2016 | |
| , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 | |
| , | Acquired by Eleven Bio, Sep 2016, $30M in stock | |
 |
Durham, NC | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| , | Gone as of Jan 2019 | |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| , | Renamed Movair, Nov 2021 | |
| , | Renamed InnoGI Technologies, Feb 2024 | |
| , | ||
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| CONMED | Largo, FL | Surgical, Medical Devices |
| , | Website down Nov 2023 - Mar 2024 | |
| , | CEO Founder Owner gone but still on website | |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| , | Acquired by eurofins, Aug 2021 | |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| , | Had 2016 Jlabs spot. No website Aug 2018. | |
| , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics | |
| , | Assets bought by Eyenovia, Oct 2014 | |
| Innocare | Shanghai, China | Cancer Treatments |
| , | Acquired by Mylan 1996 | |
| , | No website, everyone has new jobs Dec 2019 | |
| , | Merged with ProPharma, Sep 2021 | |
| , | Acquired by Sobi, Jun 2023, $1.7B | |
| Pear Bio | London, UK | Cancer Treatment Selection |
| , | Website down Apr 2020 - Oct 2020 | |
| , | Website down Aug 2023 - Apr 2024 | |
| , | Acquired by ResMed, Oct 2015 | |
| , | Bought by Amag, Sep 2014, $675M | |
| |
London, UK | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | 13 years old in 2021, founder/sole employee is part-time | |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house | |
| , | Liquidating, Jan 2023 | |
| , | Presumed gone | |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| , | Acquired by Biolog, Jan 2023 | |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| , | Out of business 2007 | |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| , | Acquired by Gener8, Dec 2021 | |
| , | Renamed Telesta Therapeutics | |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| , | Bought by Tolmar, Jul 2009 | |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| EuBiologics | Seoul, Korea | Vaccines |
| Santen | Osaka, Japan | Ophthalmics |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| , | Closed down 2017 after being convicted of Federal & CA state violations | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout | |
| , | ||
| Phenox | Bochum, Germany | Implantable devices, guidewires, thrombectomy, other devices |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| , | Bought by BMS, Aug 1996 | |
| LRE Medical | Noerdlingen, Germany | Diagnostics |
| , | Founder and Website gone, Nov 2020 | |
| Genetesis | Mason, OH | Personalized diagnosis using bioinformatics |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| , | ||
| Getinge | Gothenburg, Sweden | Medical Technology |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Evidentic | Berlin, Germany | Therapeutic Antibodies for Research/Reference Use |
| , | Dissolved Jul 2015 | |
| , | Bankrupt, Feb 2019 | |
| , | Folded into parent Alvogen | |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| , | Doesn't seem serious, Mar 2022 | |
| , | Bought by CryoLife Medical, Sep 2020 | |
| , | Website down Feb 2024 - Dec 2024 | |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| , | Gone, 2012? | |
| , | Renamed Pheon Therapeutics, Aug 2022 | |
| , | Bought by Pivot Pharmaceuticals, Nov 2015 | |
| , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn | |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| , | Acquired by OPKO, Aug 2013, renamed Opko Biologics | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Website down May 2023, CEO gone | |
 |
Gronau, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Bought by Mylan 2007 | |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| , | Renamed Cytek Biosciences, Aug 2015 | |
| , | Nothing on website, 2018-Dec 2022 | |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| Teleflex Medical | Wien, Austria | Surgical and Medical Devices |
| , | Product Acquired by Gold Standard Diagnostics | |
| , | Website down Jun 2023 - Dec 2023 | |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Shut down Jan 2006 | |
| , | ||
| , | Acquired by Invitae, Jul 2019, $65M | |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| , | Acquired by Haraeus | |
| Protai | Tel Aviv, Israel | AI-powered Drug Discovery Platform |
| , | Disappeared | |
| Seer | Redwood City, CA | Early Detection |
| Pharmascience | Montréal, QC | Generics |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| , | Now Biofarma Group | |
| Johnson and Johnson | Skillman, NJ | Consumer Products |
| , | Acquired by Mera Pharmaceuticals, Jan 2003 | |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| , | Gone | |
| , | Acquired by Merit Medical, Nov 2018, $200M | |
| , | Acquired by Kalytera, Feb 2021; Residential address May 2021 | |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| , | ||
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron | |
| , | Acquired by Exact Sciences, Mar 2020 | |
| , | Renamed Avisa Diagnostics | |
| , | ||
| Minnetronix Medical | St. Paul, MN | Therapeutic solutions that prevent secondary injury and enhance healing in neurocritical care patients |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| , | Renamed Highlight Therapeutics, Apr 2020 | |
| , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals | |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| , | Folded | |
| , | Renamed LizarBio | |
| , | Dissolved, assets acquired by Merit medical, Sep 2014 | |
| , | ||
| , | Acquired by Bard, 1980 | |
| , | Acquired by Charles River, Apr 2022, $295M | |
| Envisagenics | New York, NY | Software-based drug discovery |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| , | Renamed Venturis Therapeutics, Jan 2020 | |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| , | No news since 2007 as of Jul 2020 | |
| BerGenBio | Bergen, Norway | Target Identification & Small Molecules |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Viatris (2) | Hyderabad, India | Small Molecules |
| , | Website taken over Feb 2024 | |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| , | Website down Sep 2024 - Feb 2025 | |
| , | Acquired by Premier Research, Jul 2021 | |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| , | Bought by Chiltern, Sep 2015 | |
| Celliaz | Daejeon, Korea | Antibodies, Biologics |
| Lumanity | London, UK | Consulting |
| , | Bought by Pfizer, Jul 2016, $150M + milestones | |
| , | Website gone, CEO gone, Nov 2015, Shell Company | |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Optina Diagnostics | Montréal , QC | Ophthalmology Diagnostics |
| , | Changed name to Lean Biologix, Jan 2014 | |
| Mythic Therapeutics | Waltham, MA | Antibody-Drug Conjugates |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 | |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| , | Website down Dec 2023 - May 2024 | |
| Lumenis | Dreieich-Dreieichenhain, Germany | Energy-based medical treatments |
| , | Changed name to Bayhill Therapeutics Nov 2002 | |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Helius Medical | Newtown, PA | Translingual neurostimulation device |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| , | Website down Oct 2021 | |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| , | Renamed Elicio Therapeutics, ~May 2019 | |
| , | Don't seem to have any employees, Feb 2025 | |
| , | Changed name to PharmaCyte Biotech, Jan 2015 | |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| , | Website down Sep 2024 - Feb 2025 | |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| Dynamic Cell Therapies | Watertown, MA | CAR T Cell Therapies |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Généthon | Evry , France | Gene Therapy |
| , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M | |
| , | Renamed Wize Pharma, Nov 2017 | |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| , | Gone Mar 2010 | |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| , | Shut Down Jun 2020 | |
| , | Acquired by Takeda | |
| , | Changed name to Living Cell Technologies, 2003 | |
| , | Acquired by Kiadis Pharma, Jun 2019 | |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| , | Flagship merged it with Inzen and renamed it Sonata Therapeutics | |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 | |
| Tango Therapeutics | Cambridge, MA | Cancer Therapeutics, Immuno-Oncology |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 | |
| , | Chapter 7 bankruptcy, Feb 2023 | |
| , | Changed name to Isarna Therapeutics, Sep 2013 | |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| , | Website down Dec 2022 - Apr 2023 | |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| Quantificare | Biot, France | Medical Imaging |
| , | Renamed Imagion Biosystems, Dec 2016 | |
| Trilations | Melbourne, Australia | Strategic Consulting |
| , | Dissolved, Apr 2015 | |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| , | Now Alere | |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Cybin | Toronto, ON | Psychedelics |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| , | Website gone, Jan 2020 | |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| , | Acquired by Zoll, Aug 2019 | |
| , | Renamed Anelixis Therapeutics, Dec 2016 | |
| , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery | |
| Theragenics | Buford, GA | Medical Devices |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Dornier MedTech | Kennesaw , GA | Urology Devices |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 | |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| , | ||
| , | Website down Apr 2021 - Sep 2021 | |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Inductive Bio | Virtual, US | Compound Optimization |
| , | Gone, 2014 | |
| , | Acquired by Heptares, Nov 2016, $12M | |
| , | Website down Mar 2023 - Apr 2023 | |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| , | Everyone has new/old jobs, Jun 2022 | |
| , | Acquired by Repligen, Jul 2024 | |
| , | Acquired by Progenity, Apr 2015 | |
| , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm | |
| , | Assets acquired 2017-2018 | |
| CNS Healthcare | Jacksonville, FL | CNS Clinical Research |
| , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 | |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| , | Seem to have rebranded as Oncovalent Therapeutics, 2020 | |
| , | Merged with Pharmavize 2016, Renamed Ardena | |
| , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts | |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| , | Acquired by GSK Apr 2008, Subsumed Mar 2013 | |
| , | Shut down Feb 2014 | |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| BrainScope | Bethesda, MD | EEG characterization |
| , | Acquired by Pentax Medical, Jan 2017 | |
| , | Acquired by Allergan Dec 2012 ($350 million) | |
| , | Gone 2017 | |
| , | Professor sideline | |
| , | Shut down Jul 2024 | |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| , | Acquired by Genesis Drug Discovery, Oct 2021 | |
| Alexion Pharmaceuticals | Boston, MA | Biologics |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt | |
| Medpace | Cincinnati, OH | Clinical Research |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 | |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| , | renamed QQ Bio, May 2023 | |
| , | Website down Oct 2020 - Feb 2021 | |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| , | No info Dec 2019; Financed in 2007 | |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| , | Renamed Sio Gene Therapies, Nov 2020 | |
| , | Website down Feb 2023, executives gone | |
| , | Acquired by Bionano Genomics, Aug 2020, $9.6M | |
| , | Gone Jul 2013 | |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| , | Website redirecting to an Assisted Living Facility, Jan 2020 | |
| MJ Biopharma | Mumbai, India | Generics |
| Gensco Pharma | Doral, FL | Small Molecules Topicals |
| , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 | |
| , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 | |
| , | Renamed Sirna Therapeutics Apr 2003 | |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| , | Renamed Vera Therapeutics | |
| , | Website looks ridiculous, copyright 2005 | |
| , | Acquired by APNAR Pharma, Jul 2022 | |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| , | Acquired by Certara, Oct 2023 | |
| , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones | |
| , | Website down Feb 2022 - Jul 2022 | |
| , | fka Masy Biosystems | |
| Medelis | Thompson's Station, TN | Clinical Research |
| , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 | |
| SEngine Precision Medicine | Bothell, WA | Personalized Cancer Diagnostic/Drug Matching |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| , | Renamed KnuEdge, Jun 2016 | |
| , | Acquired by Exopharm, May 2024 | |
| , | Gone Sep 2015 | |
| Norgine | Harefield, UK | Specialty Pharma |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| , | Acquired by Medtronic, Jul 2015 | |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Hologic | Liege, Belgium | Diagnostic, Imaging |
| Advanced Instruments | Norwood, MA | Lab instruments |
| Keylicon Biosciences | Boston, MA | RNA-based Therapeutics |
| , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. | |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| , | Acquired by Northwest Biotherapeutics, Sep 2020 | |
| EXO Biologics | Liège, Belgium | Exosomes |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| , | Acquired by ICU Medical, Jan 2022, $2.35B | |
| Integra LifeSciences | Cincinnati, OH | Medical Devices |
| , | Merged with Vector Laboratories, May 2024 | |
| VIVUS | Campbell, CA | Small Molecules |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| XtalPi | Cambridge, MA | AI Drug Design |
| Pharmaron | Louisville, KY | R&D Services |
| , | Acquired by Crown Laboratories, May 2019 | |
| BioGaia | Stockholm, Sweden | Probiotics |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| , | Renamed Tetra Therapeutics, Aug 2019 | |
| Tolmar | Fort Collins, CO | Small Molecules |
| Integer | Trenton, GA | Medical & Surgical Devices |
| , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock | |
| , | Website gone, May 2018 | |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| resistanceBio | Menlo Park, CA | Cancer Drug Resistance Identification Platform |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition | |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics | |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Azzur | Irvine, CA | Consulting |
| , | Bought by MGI Pharma, Jul 2005 | |
| , | Acquired by Bayer, Sep 2020, $425M | |
| , | Renamed Bright Path Laboratories | |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| , | Renamed Alere 2011 | |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| , | Renamed Celyad, Apr 2015 | |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| , | Gone Nov 2017 | |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| , | Licensing agreement, essentially gone | |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| , | Acquired by Perrigo, May 2022, $2.1B | |
| , | Acquired by Unum Therapeutics, Jul 2020 | |
| , | Website down Sep 2024 - Feb 2025; Inside ATAI for now | |
| , | Forfeited in CA | |
| , | Website gone, Subsidiary Websites also gone | |
 |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| , | No news since 2013 as of Oct 2019 | |
| , | Website Gone 6-16-12 | |
| , | ||
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| , | Acquired by Avania, Jun 2021 | |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| , | Now part of Antibodies Inc | |
| , | Renamed ProMIS Neurosciences, Jul 2015 | |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| , | Acquired by Avanos Medical, Dec 2021, $160M | |
| Aitia | Somerville, MA | Analytics |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Wacker | Munich, Germany | Polymers, Resins |
| , | ||
| , | Acquired by PRA, renamed RPS Strategic Solutions Division | |
| , | Acquired by Bio-Rad, Jan 2017 | |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| , | Changed name to Accuratus Lab Services | |
| , | Dissolved Dec 2013 | |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| , | Acquired by Active Motif, Jan 2022 | |
| , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M | |
| , | Website down Aug 2023 - Dec 2023 | |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| , | Website gone, all employees gone | |
| , | Ceased Operations 2012 | |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| , | Renamed Lazurite | |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| BGI | Kobe, Japan | Genetic Testing |
| Resilience | Alameda, CA | Biomanufacturing |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| , | Renamed Seismic Therapeutic | |
| , | Website down Mar 2024 - Jul 2024 | |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| , | ||
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| , | website gone, company still marked as active in CA company database | |
| , | Website down Sep 2024 - Feb 2025 | |
| Evestra | San Antonio, TX | Women's Health |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| , | Website down Dec 2020 - Sep 2021 | |
| , | Renamed Tissium, May 2019 | |
| , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics | |
| , | Acquired by Norgine, Mar 2020 | |
| , | Seems gone, Sep 2022 | |
| , | Pivoted to investments | |
| , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 | |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| , | Acquired by Azurity Pharmaceuticals, Sep 2023 | |
| , | Renamed HAWK Biosystems | |
| , | Dormant 2016 | |
| , | Renamed LabCentrix, Feb 2007 | |
| , | Renamed Surface Ophthalmics, 2021 | |
| , | ||
| TFS | Lund, Sweden | Clinical Research |
| , | Charged with Securities Fraud | |
| , | Now Novum Pharmaceutical Research Services | |
| , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones | |
| XtalPi | Shanghai, China | AI Drug Design |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| , | Ceased Operations, Apr 2014 | |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| , | Shut down Dec 2020 | |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| , | Renamed Nxera Pharma, Apr 2024 | |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| , | Now Best Vascular Novoste | |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 | |
| , | Bankrupt, Assets sold to Aesculap, Feb 2018 | |
| Tenacia Biotechnology | , | |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Acquired by Lonza, May 2017 | |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| , | Website gone May 2020 - Jan 2021 | |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| , | Bought by Portage Biotech, Aug 2018 | |
| , | ||
| , | Bankrupt, Mar 2023 | |
| , | Renamed Anixa Biosciences, Oct 2018 | |
| , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX | |
| , | Acquired by Solta Medical, Feb 2010 | |
| Bayer | Mailand , Italy | Small Molecules |
| , | Shut Down Dec 2022 | |
| , | Closed Jul 2011 | |
| , | Acquired by Altasciences, Jan 2022 | |
| , | Changed name to Expedeon after acquiring them | |
| , | Acquired by Merck, Apr 2024, $208M | |
| , | Gone | |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Altay Therapeutics | San Francisco, CA | Small molecules for liver disease and cancer |
| Pace Analytical | San German, PR | Analytical Testing |
| , | Gone 2019 | |
| , | Bought by Veritas Genetics, Aug 2017 | |
| , | Merged with Notable Labs, Oct 2023 | |
| , | Acquired by Agennix, Nov 2009 | |
| , | Took name of Quotient BioDiagnostics, May 2013 | |
| , | Supposedly doing biosimilars, but no location after 8 years | |
| , | ||
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| , | Acquired by Trinity Biotech, Aug 2013, $33M | |
| , | Website Gone Dec 2013 | |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| KromaTiD | Longmont, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma | |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| , | Acquired by GSK, May 2013 | |
| Novitium Pharma | East Windsor, NJ | Generics |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Yuvan Research | Mountain View, CA | Reversing Aging |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| Empire Genomics | Depew, NY | High throughput genome-wide analysis |
| Istari Oncology | Morrisville, NC | Viral-based Vaccines, Antibody Directed Immuno-Conjugates |
| , | Merged with MedPharm, Jul 2024 | |
| Quadrant Biosciences | Syracuse, NY | Diagnostics |
| Melius Pharma | Stockholm, Sweden | Interstitial Lung Disease Treatment |
| , | Merged with DMK Pharmaceutical, May 2023, took name | |
| , | Website down Jul 2022; Not registered business in MA, Dec 2019 | |
| , | ||
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| , | Acquired by WuXi Apptec, Jan 2016 | |
| , | Acquired by Otsuka, Sep 2018, $430M | |
| , | Acquired by Acumed, Jul 2022 | |
| , | Renamed Janssen Biotech | |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| , | Merged with CARLSMED, Jul 2019 | |
| , | Website down Jul 2024 - Dec 2024 | |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| , | Acquired by Vertex, Nov 2022, $320M | |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| , | Shell Company | |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Molsid | Lyon, France | Fluorogenic Probes |
| , | Website gone Aug 2020 - Mar 2021 | |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| Gentian USA | Moss, Norway | IVD Products |
| , | Acquired by Camargo, Jun 2019 | |
| , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences | |
| , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 | |
| , | Bought by PCI Pharma Services, Jul 2014, $215M | |
| , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 | |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Gen Plus | Munich, Germany | Formulation |
| Apobiologix | Toronto, ON | Biosimilars |
| , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics | |
| , | All products acquired by TriLink Biotechnologies | |
| , | Shut down Mar 2021 | |
| , | Owned by Valeant | |
| , | Shut down April 2021 | |
| Tabby Therapeutics | Boston, | Therapeutic B cells for oncology and infectious disease |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| , | Filed for Chapter 7 bankruptcy, Jun 2018 | |
| , | Acquired by AMRI, Mar 2014 | |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 | |
| , | Renamed Freespira, Dec 2020 | |
| , | Acquired by Nordson Medical, Aug 2014 | |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 | |
| , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 | |
| , | fka Gastrotech, Site Gone | |
| KBP BioSciences | Princeton, NJ | Small Molecules |
| , | Acquired by Olympus, 2008, $2B | |
| , | Out of money, disbanded Aug 2017 | |
| PamGene | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| , | ||
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| , | Acquired by Luitpold 2010 | |
| , | Website down Apr 2021 - Sep 2021 | |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| , | Surrendered business in CA | |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| , | Website down Sep 2023 - Mar 2024 | |
| Officinae Bio | Mestre, Italy | RNA. DNA Design Platform |
| , | Closed 2008 | |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Cellenion | Lyon, France | Single Cell Testing |
| Globe Life Sciences | London, UK | Strategy Consulting |
| , | ||
| , | Presumed inactive, website gone | |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| , | ||
| Solvo Biotechnology | Budapest, Hungary | Assays |
| |
Columbia, MD | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| , | Renamed CODEX, Apr 2020 | |
| , | Shut down after owner passed | |
| Verily Life Sciences | South SF, CA | Using technology to solve health problems |
| ViaCord | Cambridge, MA | Cord Blood Banking |
| , | Appears to have been folded into Cresset Discovery Services | |
| , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics | |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| , | Fully absorbed into PureTech, Jun 2021 | |
| , | Website down Jun 2024 - Nov 2024 | |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| , | Acquired by Gedeon Richter, Jun 2016 | |
| , | Gone 2011 | |
| , | Acquired by Cook Biotech, May 2021 | |
| |
Oro Valley, AZ | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| CareDx | Brisbane, CA | Diagnostics |
| , | Assets sold off in 2011 | |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| , | ||
| , | No website Dec 2019 - Jul 2024 | |
| PromoCell | Heidelberg, Germany | Cellular Products |
| , | Part of Kyowa Kirin Group | |
| , | Website gone Jul 2015 | |
| , | Renamed Centrillion Technologies | |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| , | Presumed gone, employees gone | |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| , | ||
| MapLight Therapeutics | Boston, MA | Optogenetics |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| , | Acquired by TiGenix Mar 2011 | |
| , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich | |
| , | Website down Jul 2023 - Dec 2023 | |
| , | Bankruptcy, Oct 2021, selling company off | |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| , | Seems gone Mar 2022 | |
| , | Merged with Illumina 2006 | |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| , | Bought by Amgen 2012 | |
| , | No website Apr 2014-April2015 | |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| , | Acquired by Lilly, Jul 2018, $1.6B | |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| , | Acquire by bioMérieux, May 2022 | |
| , | Professor solo side project; MA business filings late, Jun 2024 | |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| , | Bought by Shire, Aug 2015, $300M | |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| , | Acquired by Biodesix, Jul 2018 | |
| , | ||
| , | Acquired by J&J Dec 2019 | |
| , | Acquired by Medarex, $4.7M, Jul 2004 | |
| Turnstone Biologics | Ottawa, ON | Oncolytic viral immunotherapy |
| Sopharma | Sofia, Bulgaria | Generics |
| , | Gone Sep 2010 | |
| FlexDex Surgical | Brighton, MI | Surgical Devices |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| , | Acquired by Atos Medical | |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| Chromatin Bioscience | Edinburgh, UK | Synthetic Promoters |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| , | Renamed MyricxBio, Aug 2023 | |
| , | Acquired by GEHealthcare, May 2021 | |
| , | Renamed Ysopia Bioscience, Oct 2020 | |
| , | Website taken over Mar 2024; Not registered in CA Feb 2024 | |
| , | Assets Acquired by Abryx, Apr 2013 | |
| , | Acquired via Reverse Merger by NeuroBio, Dec 2019 | |
| , | Closed | |
| , | Acquired by Roche Dec 2010 | |
| , | ||
| , | Website gone Dec 2016 | |
| , | ||
| , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout | |
| , | ||
| , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor | |
| Medicure | Winnipeg, MB | Small Molecule |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| , | Merged with Dart Neuroscience | |
| Eclipse Bioinnovations | San Diego, CA | RNA Products & Services |
| Paige | New York, NY | AI Pathology |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Createrna Science | Shanghai, China | Small Molecules |
| , | Shut down 2015? | |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| , | ||
| , | Renamed G3 Therapeutics | |
| , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator | |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| , | Intended to acquire drugs, 2019-2023 did not | |
| Kinevant Sciences | New York, NY | Sarcoidosis Treatment |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| , | Acquired by Brany, Dec 2019 | |
| Oxgene | Oxford, UK | Biomanufacturing |
| , | Acquired by Alexion, Nov 2018, $400M + $800M milestones | |
| JAMP Pharma | Boucherville, QC | Generics |
| , | Bankrupt Sep 2015, selling assets off | |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc | |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive | |
| , | Acquired by Blue Water Biotech, Dec 2023 | |
| , | Website down Mar 2020 - Dec 2020 | |
| , | Renamed Aqueduct Critical Care | |
| , | Vertex Subsidiary | |
| , | Bought by Monsanto | |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| , | ||
| , | Employees all gone Sep 2022 | |
| , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones | |
| , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name | |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| , | Acquired by Qiagen | |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| , | Website down Jun 2021 - Oct 2021 | |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| , | Website gone May 2020, Domain expired Jan 2020; Residential Address | |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| , | Website down May 2024 - Jul 2024, employees gone | |
| , | Bankrupt, Oct 2018 | |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Olon USA | Concord, OH | Contract Research |
| , | Gone Jan 2007 | |
| , | Gone | |
| , | Acquired by Takeda, Oct 2021 | |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| , | Dissolved 2014 | |
| , | Renamed Rouken Bio, Oct 2024 | |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| , | Merged with Hawaii Chitopure and became Synedgen 2009 | |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| , | Website hijacked Nov 2024; Website down Aug 2024 | |
| , | 20+ years, no products, no LI page, unfinished website Nov 2023 | |
| Peplib | ZhuZhou, China | Peptides |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Rebus Biosystems | Santa Clara, CA | Synthetic Aperture Omics |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Glen Research | Sterling, VA | Oligos |
| , | Acquired by Abcam, Mar 2020 | |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| , | Website gone May 2022 - Aug 2022 | |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| Strateos | Menlo Park, CA | Robotic Cloud Lab |
| , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 | |
| , | Bought by Evotec, Aug 2017, $300M | |
| , | Website down Dec 2021 - Jul 2022 | |
| , | Renamed Pharmatech | |
| Vaxxas | Hamilton, Australia | Vaccine patch delivery system |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| , | Website gone May 2020 - Aug 2020 | |
| , | Acquired by Abbott, Jan 2017, $25B | |
| , | No info | |
| Ergomed | Moscow, Russia | Clinical Research |
| , | part of SK pharmteco | |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| , | Acquired by Stryker as part of Wirght Medical, Nov 2019 | |
| , | Acquired by Opko Health, Oct 2011 | |
| MetaOptima | Vancouver , BC | Skin Analytics |
| AlloVir | Lexington, MA | Allogeneic, Off-The-Shelf, Multi-Virus Specific T-Cell Immunotherapies |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| , | Acquired by Perkin-Elmer, Feb 2006 | |
| Chanelle Pharma | Amman, Jordan | Generics |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| , | Website not active, redirects to another inactive Website as of Nov 2016. No info | |
| , | No website Jan 2020 - Aug 2021; 2018 or earlier startup | |
| CRS Clinical Research Services | Mannheim, Germany | Clinical Research |
| , | Acquired by Agilent, Aug 2019 | |
| , | Bankrupt Jun 2024; Website down Oct 2024 | |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| , | No info, Nov 2021 - Jul 2024 | |
| , | Renamed Hone Bio, Nov 2024 | |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| , | Bought by Millipore, May 2012 | |
| , | Merged with CuraCyte, Jun 2002 | |
| , | Acquired by Zimmer Biomet, Dec 2020, $250M | |
| , | Shut Down 2019 | |
| , | New in 2015, quickly disappeared from VC website | |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| , | Acquired by Ethos Biosciences, Nov 2018 | |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| 23andMe | South SF, CA | Consumer DNA Testing |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| , | Defunct | |
| , | ||
| , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic | |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Meissner | Camarillo, CA | Lab Systems |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 | |
| , | Changed name to Aduro Biotech, Jun 2008 | |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| , | Merged with Strides Arcolab, Nov 2015 | |
| , | Acquired by J&J, Dec 2019 | |
| Bioclonal | Zaragoza, Spain | Antibody Discovery Technology |
| , | Website gone Nov 2018, Had FTC problems | |
| , | Acquired by Eli Lilly Jul 2008 | |
| , | Website gone Jan 2023 - Jul 2023 | |
| , | Website down, Dec 2022 - Sep 2023 | |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| , | Acquired by PDS biotechnology, reverse merger, Mar 2019 | |
| , | Website down Nov 2023 - Mar 2024 | |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| , | Gone | |
| , | Gone, May 2018 | |
| , | Renamed Cerba Research | |
| , | Closed on Google Aug 2022 | |
| , | ||
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B | |
| , | Gone Dec 2016 | |
| , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 | |
| , | ||
| , | Presumed Gone | |
| , | ||
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 | |
| , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition | |
| , | Website down Apr 2024 - Aug 2024 | |
| , | Closed Jul 2016 | |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| , | Gone Jul 2019 | |
| Vyaire Medical | Mettawa, IL | Respiratory-related Devices |
| , | No news since 2006, Website gone | |
| PackGene Biotech | Houston, TX | Customized AAV vector cloning/packaging services |
| , | Website taken over Feb 2022 | |
| , | Acquired by Hologic, Jul 2018, $85M | |
| Cytiva | Burnaby, BC | Cell Culture Products |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Foresight Diagnostics | Aurora, CO | Cancer Diagnostics |
| Axplora | Chennai, India | API manufacturing |
| , | ||
| , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones | |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon | |
| EarliTec Diagnostics | Decatur, GA | Autism Diagnosis |
| , | Renamed Supira Medical, Mar 2016 | |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| , | Bought by Allergan, Sep 2016, $60M | |
| , | Acquired Allergan, $70B, Took Allergan name | |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| , | No annual report filed 2013-2019 | |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Jan Medical | Mountain View, CA | Brain Pulse Device |
| , | Assets Acquired by SmooFi, Oct 2016 | |
| , | Merged with UBC | |
| , | Platform acquired by AbCellera, Aug 2020 | |
 |
Utrecht, Netherlands | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| , | Bought by AMRI, May 2016, $358M | |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| , | Changed name to Trillium Therapeutics, Jun 2014 | |
| , | Bought by Intrexon, Jun 2017, $16M in stock | |
| AdipoSeeds | Tokyo, Japan | Platelets from Fat |
| , | Bought by Merck, Jun 2014 | |
| InnoMedica | Zug, Switzerland | Liposomal drug transport systems |
| Gensaic | Cambridge, MA | Phage-derived Particles for Gene Delivery |
| , | Acquired by Cubist Sep 2013 | |
| , | Acquired by Galapagos Jun 2022, $14M | |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| , | Website Down Nov 2022 - Mar 2023 | |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| , | Now YS Biopharma | |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| , | Appears Gone Sep 2017 | |
| Aixial Group | Montpelier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| , | ||
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| , | Renamed Kinapharma, 2020 | |
| , | Acquired by Chiesi, Aug 2013 | |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| , | Renamed Speech Buddies, Dec 2015 | |
| , | No info. Jun 2015. $1.5M SBIR grant 2011 | |
| , | Website down Dec 2020 - Mar 2021 | |
| SomaLogic | Boulder, CO | Blood Analysis |
| , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 | |
| , | Bought by Merck Aug 2010? | |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 | |
| , | Renamed Lisata Therapeutics, Sep 2022 | |
| , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 | |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed | |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| , | ||
| CrelioHealth | Wilmington, DE | LIMS |
| , | ||
| , | Website down Dec 2023 - May 2024 | |
| , | Renamed Soovu Labs, May 2019 | |
| Pfizer | Puurs, Belgium | Packaging |
| Cytiva | Piscataway, NJ | Medical Devices |
| , | Acquired by SomaLogic, Jul 2022, $35M | |
| Alnair Therapeutics | Chicago, | Oncology Drugs |
| , | Renamed Tricol Biomedical | |
| , | Renamed HealthBio AI | |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Gone, not sure what happened | |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| , | ||
| EpiBone | Jersey City, NJ | Personalized Bone Grafts |
| , | Gone | |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| , | Website gone Jul 2015 | |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| , | Website gone Mar 2023; working on foods | |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Veeva Systems | Shanghai, China | Life Science Software |
| , | ||
| , | Acquired by Parse Biosciences, Jan 2024 | |
| Antabio | Labège, France | Antibacterial drugs |
| , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 | |
| Evofem Biosciences | San Diego, CA | Women's health |
| , | Shut down, Dec 2024 | |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| , | Founders gone. Doubt it's active | |
| Ergomed | Kiev, Ukraine | Clinical Research |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| , | ||
| , | Acquired by Charles River Laboratories, Apr 2018, $800M | |
| , | Now Terumo Neuro | |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| iTeos Therapeutics | Watertown, MA | Cancer Immunotherapy |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| , | Acquired by Ximedica, Jul 2016 | |
| ONWARD | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones | |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| Nostrum Laboratories | Kansas City, MO | Generics |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| , | Acquired by Ligand, Jan 2016, $178M | |
| , | Renamed Advanz Pharma, Oct 2018 | |
| , | Acquired by GSK, Feb 2015, $190M | |
| Parexel | South Yorkshire, UK | Clinical Research |
| , | ||
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| , | ||
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Gennova Bio | Pune, India | mRNA vaccine |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| , | Merged with Scios, May 1992 | |
| , | Acquired by AstraZeneca, Nov 2022, $68M | |
| Blueberry Therapeutics | Cheshire, UK | Dermatological Small Molecules |
| , | No website, no info Feb 2021 | |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| , | Website gone Dec 2023 - May 2024 | |
| , | Acquired by Agilent, Jan 2018 | |
| , | Acquired by Fujirebio Europe, Sep 2010 | |
| , | CEO is with new company, website gone, company presumed gone | |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| , | Website down Dec 2022 - Apr 2023 | |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| , | Assets bought by Neogen | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners | |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| , | ||
| , | was partnering with Illumina, then became "an Illumina company" with no news | |
| , | Acquired by Sema4, Jan 2022, $623M | |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Merged with Karmelsonix to become iSonea, 2011 | |
| Proteintech | Manchester, UK | Research Antibodies |
| , | Merged out of life sciences, Dec 2014 | |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| Biopharma Research | Nether Poppleton, UK | Research Services |
| , | Assets acquired by Bigfoot Biomedical, May 2015 | |
| Heraeus Medical | Changshu, China | Medical Devices |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| , | Renamed Alpinion Medical Systems, 2010 | |
| , | Bought by Roche, Oct 2015, $105M + $475 Milestones | |
| , | Acquired by Mylan, 2007 | |
| , | Renamed American Regent | |
| , | Merged into CannBioRx, Jul 2019 | |
| , | Gone 2024 | |
| , | Assets auctioned, Acquired by Pulmonx Jan 2015 | |
| GlycoTherapeutics | Nijmegen, Netherlands | Cancer Immunotherapies |
| , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London | |
| , | Merged with Q32 Bio Mar 2024 | |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma | |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| , | Shut down Nov 2023 | |
| , | Website down Jul 2021 - Dec 2021 | |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| SphingoTec | Hennigsdorf, Germany | Breast cancer diagnostic |
| Eton Bioscience | San Diego, CA | Research Reagents, Kits, Peptides, Services, etc. |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| , | Acquired by LabCorp, $1.2B, Jul 2017 | |
| , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones | |
| , | 10-yr Sideline | |
| , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 | |
| , | Acquired by J&J, Mar 2011, $2.3B | |
| , | no news since 2016 as of Dec 2020, residential address | |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| , | Bought by JLL then merged with Bioclinica, 2013 | |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Therorna | Beijing, China | RNA Therapies |
| , | Bought by Covidien, 08/14 | |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| Bracco | Milan, Italy | Imaging |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| , | No website, no info Sep 2020 - May 2023, seems like solo person | |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Intelliseq | Kraków, Poland | Genome Informatics |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary | |
| , | aka sRNAlytics | |
| , | Gone 2019 | |
| , | Gone? | |
| , | Ran out of money | |
| Curia | Rensselaer, NY | Contract Research, Development, Manufacturing |
| , | Acquired by Parexel, Mar 2004 | |
| , | Changed name to Targazyme | |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 | |
| , | ||
| , | Website down Jul 2023 - Dec 2023 | |
| , | Bought by Charles River, Apr 2016, $585M | |
| TWi Pharmaceuticals | Taipei, Taiwan | High barrier generics |
| DxTerity | Torrance, CA | Genomic Testing |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| , | Shut down Dec 2019 | |
| , | Acquired by Leica Biosystems, Jul 2013 | |
| , | Everyone has other, seemingly more important jobs | |
| Gilead | Oceanside, CA | Small Molecules |
| , | Acquired by Dermira, Oct 2011 | |
| , | ||
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| Edinburgh Molecular Imaging | Edinburgh, UK | Image-guided Therapy |
| , | ||
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| , | Changed name to YourGene Bioscience, Nov 2018 | |
| UCB Pharma | Mannheim, Germany | Small Molecules, Biologics |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| , | Website down Oct 2020 - Mar 2021 | |
| , | Website gone Aug 2022 | |
| , | Renamed Vivoryon Therapeutics, Jun 2019 | |
| , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M | |
| , | Business filings late Feb 2023; No news 2020 - Aug 2024 | |
| Profil | Neuss, Germany | Clinical Research Services |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| , | Bought by VWR Nov 2016 | |
| , | Now Theorem Clinical Research | |
| , | ||
| , | Website down, Jan 2020 - Sep 2020 | |
| , | Website under construction since 2011 | |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| , | Website down Dec 2019, never even registered as a business in CA | |
| , | Acquired by H-Cyte, Sep 2022 | |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| , | Presumed gone; fka Ascent Therapeutics | |
| Tirupati | Pune, India | Generics |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| , | Acquired by EMD Millipore, Aug 2011 | |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences | |
| , | Acquired by Integra LifeSciences, Jan 2021, $300M | |
| , | ||
| bioMerieux | Lombard, IL | Diagnostics |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| , | Reverse Merged with Brickell Biotech, Jun 2019 | |
| , | Merged with CalciMedica, Mar 2023 | |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| , | Website down Aug 2022 | |
| , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director | |
| Creative Enzymes | Shirley, NY | Enzymes |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| , | Merged with Quoin Pharmaceuticals, Mar 2021, took name | |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| , | No website, Aug 2018, public shell | |
| Standard Bariatrics | Cincinnati, OH | Bariatric Clamps |
| , | ||
| |
Basel, Switzerland | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| , | ||
 |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Dissolved, Jun 2019 | |
| , | ||
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| LumaBridge | San Antonio, TX | Clinical Research |
| , | Acquired by Venus Medtech, Dec 2021 | |
| , | Acquired by Centessa Pharmaceuticals | |
| , | Shut Down May 2013 | |
| , | Website down Jul 2024 - Dec 2024 | |
| , | ||
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Synthace | London, UK | Development Software |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| , | Renamed Micelle BioPharma | |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| , | ||
| Polynoma | San Diego, CA | Melanoma Vaccine |
| , | ||
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| EAG Laboratories | El Segundo, CA | Analytical & Synthesis Services |
| , | No website update since 2005 as of Apr 2019 | |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Imuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| , | Renamed Lifeward, Jan 2024 | |
| , | One-person, has different job, severely empty & outdated website | |
| , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B | |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| , | ||
| , | ||
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 | |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Seraxis | Germantown, MD | Cell Therapy for Diabetes |
| Vertex | Cambridge, MA | Small Molecules |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Cellworks | South SF, CA | Biosimulations |
| Xylyx Bio | Brooklyn, NY | ECM substrate |
| , | Acquired by Roche, Jun 2014 | |
| , | Bought by Celgene 2009 | |
| , | Clinical Trials Research Services | |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active | |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| , | Acquired by LabCorp, 2021 | |
| , | ||
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Eminent Services | Frederick, MD | Drug Services |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| , | Shut Down 2009 | |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| , | Acquired by Sherlock Biosciences, Feb 2023 | |
| , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica | |
| , | Shut down, ~2022 | |
| , | Renamed Spirosure | |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| , | Website down Oct 2021 - Feb 2022 | |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| Norac Pharma | Azusa, CA | API Manufacturing |
| , | 2015 founded, website never active | |
| , | Acquired by Medtronic, Nov 2010, $800M | |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| , | ||
| , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone | |
| , | Acquired by Recipharm, Feb 2022 | |
| , | Website down May 2022 - Oct 2022 | |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution | |
| , | ||
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| KALA BIO | Arlington, MA | Drug Delivery |
| , | Presumed gone, website gone Jan 2019 | |
| , | Acquired by Boston Scientific, Nov 2023, $850M | |
| GenEdit | Brisbane, CA | Nonviral CRISPR-delivery system |
| , | Renamed TrueBlue Clinical Research, Jun 2022 | |
| , | ||
| , | Precision Virologics | |
| Anavex Life Sciences | New York, NY | Small Molecules |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| , | Shut down 2021 | |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| Advancells | Noida, India | Stem Cell Treatments |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| , | Renamed NFL Biosciences | |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| R-Pharm | Moscow, Russia | Medical Equipment |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| , | Funding cut off Apr 2017 | |
| , | Acquired by Solve Therapeutics, Jun 2023 | |
| , | Renamed Previse, Mar 2023 | |
| , | Acquired by Piramal, Apr 2021, $106M + Milestones | |
| , | Acquired by Centessa | |
| , | Acquired by Veris Health, Jun 2021 | |
| , | Out of business, 2016 | |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Proteinea | Cairo, Egypt | AI-Based protein Discovery |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| , | Renamed Verinos Pharma, Jan 2023 | |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| , | Acquired by Neurelis, Dec 2018 | |
| , | Website down Oct 2022 - Apr 2023 | |
| , | Seem gone, 2020 | |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| , | ||
| , | Dissolved Apr 2016 | |
| Devsynthesis | Austin, TX | Chemistry CRO |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| , | ||
| , | Bought by Shire, Sep 2009 | |
| , | Folded into OpGen, Dec 2021 | |
| , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona | |
| , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals | |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Novartis | Emeryville, CA | Diagnostics |
| , | Acquired by RTI Surgical, Mar 2019 | |
| , | Gone, Sep 2012 | |
 |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| , | Acquired by Bionano Genomics, Oct 2021 | |
| , | Acquired by TE Connectivity, Apr 2016, $895M | |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| , | ||
| , | Website gone Jul 2015 | |
| , | President gone, website outdated showing him still there. Doubt this company is active. | |
| , | Bought by Eli Lilly, Feb 2004 | |
| GenSure | Shijiazhuang, China | Diagnostics |
| , | Bought by PerkinElmer, Jan 2016 | |
| pHion Therapeutics | Belfast, UK | Nanoparticle Drug Delivery |
| SOCIUM | Tokyo, Japan | Contract Research |
| , | Renamed AntiRadical Therapeutics | |
| OraSure | Bethlehem, PA | Diagnostics |
| , | Renamed AITIA, Jan 2023 | |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Resolve Biosciences | Monheim am Rhein, Germany | Molecular Cartography |
| , | Bought by Pfizer, Sep 2010 | |
| , | ||
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| , | ||
| , | Renamed Gilero, Oct 2019 | |
| , | Now part of HP Health | |
| , | ||
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| , | Shut down Sep 2022 | |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| , | Shut down, Oct 2017 | |
| , | Renamed Samay Health, Oct 2022 | |
| , | Acquired by CareMetx, Oct 2018 | |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| , | ||
| AROG Pharmaceuticals | Dallas, TX | Small Molecules |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Renamed Proclara Biosciences, Sep 2016 | |
| , | Website down May 2022 -Sep 2022 | |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| , | Renamed Elucid, Jan 2022 | |
| , | Acquired by Origene, fka Cambridge Bioscience | |
| , | Merged with Cyclacel, Dec 2005 | |
| Hovione | Mumbai, India | Contract Manufacturing |
| , | Acquired by Zealand Pharma, Feb 2020, $23M | |
| , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M | |
| , | Renamed enVVeno, Sep 2021 | |
| , | Bought by DSM | |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Acquired by skiing company in reverse merger, Dec 2013 | |
| , | Now CenExelACT | |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| , | Owned by Menarini | |
| , | Acquired by Stryker, Sep 2013, $1.65B | |
| , | Shut down Dec 2022 | |
| , | Switched business model from drugs to funeral services, 1999 | |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| , | Website down Apr 2023 - Sep 2023 | |
| , | ||
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| BGI | Shenzhen, China | Genetic Testing |
| , | Dissolved, Pre-2005 | |
| Minaris Regenerative Medicine | Ottobrunn, Germany | Cell Therapy Development Support |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ | |
| , | Acquired by Azurity, Sep 2021 | |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| , | Acquired by Actavis, Apr 2007 | |
| , | Website Gone, Aug 2016 | |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL | |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Certified GeneTool | Pleasanton, CA | Refurbished Biotech Equipment |
| , | Acquired by Chernwood Molecular, Jun 2021 | |
| BrainsWay | Burlington, MA | Device for Brain Disorder Treatment |
| GeneType | Fitzroy, Australia | Genetic Testing |
| , | Acquired by Zimmer Biomet, Jul 2016 | |
| , | Acquired by Pace Analytical, Dec 2017 | |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| , | Dissolved Feb 2017 | |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| , | Rolled into Accroma Labtec, Nov 2023 | |
| Grunenthal | Quito, Ecuador | Small molecules |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| , | Renamed Lerna Biopharma, Sep 2023 | |
| , | Website gone Sep 2017 | |
| , | Renamed Diasorin? | |
| KinSea Lead Discovery | Tromsø, Norway | Marine Bioactives |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| , | Website down Oct 2020 - Feb 2021 | |
| , | Renamed TGC Lifesciences | |
| , | Gone 2018 | |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| , | Merged with Aytu BioScience, Mar 2021 | |
| , | Rebranded Rakuten Aspyrian, Aug 2018 | |
| Kura Oncology | San Diego, CA | Small Molecules |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| , | Renamed Metrics Contract Services | |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| , | Bought by Medicinova, Dec 2009, $37M | |
| , | Acquired by Novus Biologicals Oct 2013 | |
| , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones | |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| , | Renamed Revolo Biotherapeutics | |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| genOway | Lyon, France | Rat and cell models |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Transgene | Lyon, France | Viral Vector Therapeutics, Gene Therapy |
| , | All employees gone as of Dec 2017 | |
| , | Owned by Morphogenesis | |
| , | Acquired by BiomX, Mar 2024 | |
| , | Bought by BMS, Feb 2015, $800M + $450M milestones | |
| , | Renamed Vivesto, Mar 2022 | |
| Certus | Bedford, NH | Imaging Clinical Trials |
| , | Renamed Kashiv BioSciences, Jan 2019 | |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| T2 Biosystems | Lexington, MA | Diagnostics |
| , | Failed | |
| , | Website under construction Dec 2022 - Jul 2023 | |
| Micregen | Cheshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| , | Employees gone, no info, presumed defunct | |
| , | Acquired by Cenexel, Aug 2021 | |
| , | Website down Mar 2023 - Dec 2023 | |
| SageMedic | Redwood City, CA | Tumor assay |
| , | Merged with Mateon Therapeutics, Apr 2019 | |
| Alzinova | Gothenburg, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| , | Bought by Brooks Automation Apr 2011 | |
| , | Merged with Klogene, Dec 2017 | |
| , | Acquired by The Medicines Company Dec 2013, $140M | |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Biopharma Group | Plymouth, MI | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Natera | San Carlos, CA | Prenatal Testing |
| , | Bought by The Medicines Company, Sep 2013 | |
| , | Bankrupt Mar 2023 | |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Roowin | Riom, France | Chemical Synthesis |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Now Ei | |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 | |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| , | Gone 2017 | |
| , | Website Gone Oct 2017 | |
| , | Acquired by Par Pharmaceutical, Aug 2011 | |
| Cellbricks Therapeutics | Berlin, Germany | Implantable Cell Therapies |
| , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments | |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| , | Now Mederi-RF | |
| , | Website down Jul 2022 - Nov 2022 | |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| , | No news 2020 - Jan 2025; Founder gone 2023 | |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| , | No CA business filings Mar 2016 - Dec 2019 | |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| , | Can't find info on it | |
| , | Website gone May 2018 | |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| , | Renamed Guard Therapeutics | |
| Xequel Bio | Fort Worth, TX | Peptide for Injury Healing |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Clinnex | Ahmedabad, India | Clinical Research |
| , | Renamed Argent BioPharma, Feb 2024 | |
| , | ||
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| , | Seem to be subsidiary of NKT Therapeutics | |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| , | Website copyright 2012 as of Apr 2021 | |
| , | Bought by LabCorp, Nov 2014, $85.3M | |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| Profound Medical | Mississauga, ON | Real-time MRI |
| , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics | |
| , | ||
| , | Shell acquired for a security business | |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| , | Shut down 2021 | |
| , | Acquired by Endpoint Health, Jun 2022 | |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| , | Shut Down 2019 | |
| , | Acquired by Integra | |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| , | Dissolved Nov 2019 | |
| , | Renamed Tharimmune, Sep 2023 | |
| , | ||
| Catawba Research | Charlotte, NC | Clinical Research |
| EchoPixel | Santa Clara, CA | 3D Surgical Imaging |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular | |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| , | Shut down Nov 2024 | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Renamed UroGen Pharma | |
| , | Website down Dec 2022 | |
| George Clinical | Sydney, Australia | CRO providing a full range of trial management services. |
| , | Shut down Nov 2023 | |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| , | Bought by AMRI | |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| NovoCodex Biopharmaceuticals | Shaoxing, China | Biologics |
| , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics | |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| , | Acquired by eurofins, Sep 2018 | |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| , | Changed name to Akashi Therapeutics, Jun 2014 | |
| , | Gone | |
| , | Changed name to Pascal Biosciences, Mar 2017 | |
| , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 | |
| , | Website empty Sep 2024 - Feb 2025 | |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| Varian Medical Systems | Palo Alto, CA | Medical Devices & Software |
| , | Acquired in Reverse Merger by media company, presumably for ticker symbol | |
| , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics | |
| Percival Scientific | Perry, IA | Incubators |
| , | Website down Jan 2024 - Sep 2024 | |
| , | Bought by Millennium 2011 | |
| , | Acquired by Covidien, Nov 2011, $325M | |
| , | Renamed PhenomeX, Mar 2023 | |
| , | Website gone May 2022; under construction Nov 2021 - Apr 2022 | |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| Centinel Spine | West Chester, PA | Spinal Implants |
| NuvOx Pharma | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics | |
| Tecomet | Kenosha, WI | Implant Components |
| , | Assets acquired by Pulmonx, May 2009 | |
| , | Acquired by Werfen, Mar 2023, $2B | |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Chanelle Pharma | London, UK | Generics |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| , | Acquired by Alexion Feb 2012 | |
| , | Website down Sep 2024; CA filings late Dec 2023 | |
| , | Acquired by Agilent, Nov 2018 | |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| , | Website down Sep 2021 - Jan 2022 | |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| , | Renamed Hepion Pharmaceuticals, Jul 2019 | |
| Therabest | Seoul, Korea | iPSC |
| Cloudbyz | Naperville, IL | Clinical Trial Management Software |
| , | No updates since 2008 as of Sep 2020 | |
| , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 | |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| MDI Membrane Technologies | Camp Hill, PA | Separation Products |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| , | ||
| , | Gone | |
| Baylor Genetics | Houston, TX | Genetic Testing |
| , | Acquired by Predictive Technology Group, Mar 2019 | |
| Getinge | Antalya, Turkey | Medical Technology |
| , | Renamed Phio Pharmaceuticals, Nov 2018 | |
| , | Renamed ACI Clinical | |
| , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals | |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| , | ||
| Vanessa Biotech | Budapest, Hungary | Treatments for underserved populations |
| , | Acquired by Auxilium Pharmaceuticals, Apr 2013 | |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| , | Renamed Alterity Therapeutics, Apr 2019 | |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| Mankind Pharma | New Delhi, India | OTC? |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River | |
| Laurus Labs | Hyderabad, India | API manufacturing |
| , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 | |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 | |
| , | Renamed Exeliom Biosciences, Jan 2019 | |
| , | ||
| , | Renamed NRx Pharmaceuticals | |
| , | Renamed RevealDx | |
| , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 | |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Stemson Therapeutics | San Diego, CA | iPSC Hair Loss Treatment |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| , | Renamed Tarveda Therapeutics, Jan 2016 | |
| , | ||
| , | Bought by ABL inc, Jul 2014 | |
| , | Acquired by Pharmaxis, 2010 | |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| , | Shut down Mar 2009 | |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| , | Renamed CATO-SMS | |
| AIM Biotech | Singapore, Singapore | Non-animal Preclinical Models |
| , | Renamed Superfluid Dx, Oct 2023 | |
| , | Acquired by Skye Bioscience, Aug 2023 | |
| , | Acquired by SERB, Mar 2021 | |
| , | Changed name to Fennec Pharma, Sep 2014 | |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| , | Renamed Pionyr Therapeutics | |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| , | Liquidated, Sep 2015 | |
| , | Website gone, Apr 2019 | |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| , | Acquired by Hitachi Chemical, Apr 2019 | |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Omeros | Seattle, WA | Small Molecules |
| , | Gone 2016 | |
| , | ||
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| , | Gone 2015 | |
| , | Gone Jul 2022 | |
| , | Renamed Travere Therapeutics, Nov 2020 | |
| , | Website down Jun 2024 - Nov 2024 | |
| , | Renamed Cortice Biosciences | |
| Clario | Philadelphia, PA | Clinical Services |
| , | Website taken over Aug 2020 | |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | ||
| , | Website down Apr 2024 - Aug 2024 | |
| Myomo | Boston, MA | Arm brace to support and move weak arm |
| , | Dissolved, Dec 2016 | |
| , | Acquired by Century Therapeutics, Apr 2024 | |
| Altasciences | Auxvasse, MO | Contract Research |
| , | Closed Sep 2007 | |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| Roche | Burgess Hill, UK | Diagnostics |
| Calida Therapeutics | Paris, France | |
| DDL | Irvine, CA | Device Testing |
| , | Website down Mar 2023 | |
| Johnson and Johnson | Lilitz, PA | Consumer Products |
| Berry Oncology | Fujian, China | Precision Diagnostics for Oncology |
| , | ||
| Bayer | Berlin, Germany | Small Molecules |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| , | Changed named to Aqua Bounty 2004 | |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M | |
| , | Assets auction, Aug 2017 | |
| , | No news 2016 - Oct 2024, No linkedin | |
| , | Shut down Oct 2021; fka Biodesy | |
| , | Behind on taxes in CA | |
| , | Acquired by Recipharm, Feb 2022 | |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| , | Website down Jun 2021 - Dec 2021 | |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| , | Acquired by Alira Health, Apr 2022 | |
| American Regent | Shirley, NY | Generics |
| , | Website down Dec 2020 - May 2021 | |
| , | Acquired by Roivant, Feb 2021, $450M | |
| , | Shut down after angering FDA with Covid test, 2022 | |
| , | Renamed Castle Creek Biosciences | |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Renamed Neuraxis, May 2022 | |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| , | Bought by 3M, Oct 2019, $6.7B | |
| , | Website down Oct 2021 - May 2022 | |
| , | Attack website | |
| NS Pharma | Cambridge, MA | Small Molecule |
| , | Merged into Galvanize Therapeutics, 2022 | |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Pfizer | McPherson, KS | Sterile Injectables |
| , | Acquired by Cancervax | |
| Clarapath | Hawthorne, NY | Pathology Device |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| WestGene | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| , | No Site | |
| , | Website down Jan 2019 - Mar 2019 | |
| , | Acquired by Pharmion, Nov 2006 | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Renamed VeraSci, Oct 2018 | |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| , | folded into LabCorp proper? | |
| , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 | |
| NH TherAguix | Meylan, France | Tumor-targeting Nanoparticle |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| , | Website Gone, Jul 2014 | |
| , | Changed name to Ikano Therapeutics 2009 | |
| , | ||
| , | Acquired by Galderma, Feb 2008, $420M | |
| , | Website down May 2021 - Sep 2021 | |
| , | Acquired by Horizon Pharma, May 2017, $145M | |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Engine Biosciences | Redwood City, CA | AI & genomics |
| , | Acquired by Convatec, Mar 2022 | |
| , | Founder has new job, Jul 2021 | |
| Cyclacel Pharmaceuticals | Berkeley Heights, NJ | Small Molecules, Biologics |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| , | Acquired by Celgene, Dec 2009, $340M + $300M milestones | |
| , | Gone | |
| , | Acquired by Illumina, Sep 2015 | |
| , | Acquired by Medic Biochemica, Jun 2020 | |
| , | Bought by Novartis, Nov 2017, $3.9B | |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| , | Renamed Molecure, Apr 2022 | |
| Piezo Therapeutics | Atlanta, GA | Nucleic Acid Drug Delivery |
| , | ||
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| , | Acquired by Helsinn 2009 | |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| , | Bought by Lilly, Nov 2010, $800M | |
| , | Website down Aug 2021 - Sep 2021; fka Snorx | |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| , | Bought by Merck KGaA, Jun 2018, $394M | |
| , | ||
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| , | Website down Jan 2022 - May 2022 | |
| , | Renamed Pinion Immunotherapeutics, Jan 2025 | |
| Vanessa Biotech | Hamden, CT | Treatments for underserved populations |
| , | Gone | |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| , | Website down Sep 2022 - Feb 2023 | |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| , | Now BiomericsATL | |
| , | Website down Apr 2022 - Jul 2022 | |
| Athens Research and Technology | Athens, GA | Purified human proteins |
| , | Website down Apr 2019 - Aug 2019 | |
| |
Canton, MA | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes | |
| , | Acquired by VWR, Feb 2011 | |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| , | Bought by Takeda, Jan 2019, $62B | |
| , | Acquired by Siegfried, May 2012 | |
| , | Shut down Oct 2024; aka ProLung | |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| , | Everyone gone Oct 2022 | |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| , | Website gone Feb 2021; Yale affiliated | |
| , | Gone 2012 | |
| , | Website gone Apr 2021 | |
| Avance Clinical | Firle, Australia | Clinical Research |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| , | Acquired by uniQure, Jun 2021, $55M + $240M milestones | |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| , | Effectively bankrupt, Mar 2018 | |
| , | Renamed Enlivex Therapeutics | |
| , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 | |
| , | Website down Oct 2023 - Apr 2024 | |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| , | Merged with Laronde, Oct 2023 to become Sail Biosciences | |
| NeoVentures | London, ON | Custom Aptamers |
| , | Liquidated | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Renamed BioTelemetry, Jul 2013 | |
| , | Bought by Allergan, Jul 2015, $125M | |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| MC3 Cardiopulmonary | Dexter, MI | Extracorporeal Membrane Oxygenation Device |
| , | Ancient website hasn't been updated since the year the company was founded (2007) | |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| , | Renamed Verlyx Pharma, 2015 | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Bought by J&J, Sep 2010 | |
| , | Website down Dec 2017-May 2018 | |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| , | Acquired by Zymeworks | |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| , | No website, shell company Nov 2020 | |
| Stat One | Morrisvile, NC | eClinical |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| , | Renamed Abliva, May 2020 | |
| TheWell Bioscience | North Brunswick, NJ | 3D Hydrogel Platform |
| Heraeus Medical | Dorado, PR | Medical Devices |
| , | Renamed Immune Regulation, Nov 2019 | |
| , | ||
| , | ||
| , | 10 years old, only CEO on LI who has always had diff job | |
| , | Acquired by Stryker, Mar 2024 | |
| , | Acquired by Cipher Pharmaceuticals, Apr 2015 | |
| , | Merged into Evelo Biosciences, Jul 2016 | |
| , | Renamed Altamira Therapeutics | |
| , | Renamed Symeres, Dec 2020 | |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| Adept Therapeutics | Beverly, | |
| , | Website taken over, Sep 2017 | |
| , | Renamed G&L Healthcare Advisors, Jan 2023 | |
| , | No website Jan 2020 - Jul 2024 | |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Theragent | Arcadia, CA | Cellular CDMO |
| , | Acquired by Kelpac, Jan 2016 | |
| Biolab Pharma | São Paulo, Brazil | Small Molecules |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| , | Gone | |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| , | Acquired by Riemser, Oct 2019 | |
| , | Renamed Serum Life Science Europe, Sep 2023 | |
| , | Renamed BlueSky Immunotherapies | |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| , | Gone 2006-2007 | |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Syneos Health | Newtown, PA | Clinical Development |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 | |
| Terns Pharmaceuticals | Foster City, CA | Small Molecules - Liver focus |
| , | Acquired by ReproCELL, Sep 2014 | |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| Adela | Toronto, ON | Liquid Biopsy |
| , | Acquired by ICON plc, Feb 2019 | |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals | |
| , | Website down Jul 2021 - Dec 2021 | |
| , | Acquired by Meridian Bioscience, Apr 2020 | |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| TesoRx | Menlo Park, CA | Formulations platforms |
| , | Website down early 2021 - Apr 2022 | |
| Getinge | Hechingen, Germany | Medical Technology |
| , | Merged with Tectonic Therapeutics, Jun 2024 | |
| , | Switched to Cosmetics, trying to sell company Jun 2016 | |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Curio Bioscience | Palo Alto, CA | High Resolution Spatial Biology |
| , | Website gone, employee gone | |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| , | Website under construction Oct 2021 - Jul 2022 | |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| , | Acquired by Axol Bioscience, Oct 2024 | |
| , | Website down May 2023 - Sep 2023 | |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Neurogene | New York, NY | Genetic Therapies |
| , | Website down Feb 2021 - Oct 2021 | |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| , | Bought by Chinese Investor, Jan 2016 | |
| , | Website down Jun 2021 - Oct 2021 | |
| , | Renamed Veravas, Nov 2018 | |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| , | One employee, website gone | |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| , | Assets acquired by Schering-Plough, Jan 2005 | |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| , | Closed as of 2014 | |
| , | Acquired by Thermo Fisher, Oct 2021 | |
| Galen Robotics | Baltimore, MD | Microsurgery Robotics |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| , | Renamed Cambridge Analytical Laboratories, Dec 2019 | |
| , | Gone, 2014 | |
| , | Renamed TuHURA Biosciences, Dec 2023 | |
| , | Acquired by Lygos, Jan 2020 | |
| Senseonics | Germantown, MD | Medical Devices |
| , | Acquired by Apellis Pharmaceuticals, Nov 2014 | |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| , | Merged with BioAlliance Pharma to become Onxeo | |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| , | Bankrupt 2014 | |
| , | Acquired by Liquidia, Jun 2020 | |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| , | Acquired by Tricentis, Mar 2022 | |
| , | Acquired by X-Chem, Oct 2021 | |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC | |
| , | Acquired by Smith + Nephew, Jan 2022, $135M | |
| , | ||
| Abbexa | Cambridge, UK | Antibodies, Research products |
| PolyActiva | Parkville, Australia | Drug-polymer conjugate technology, implants |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| ROME Therapeutics | Boston, MA | Drugging Junk DNA |
| , | ||
| Medtronic | Brooklyn Center, MN | Medical Devices |
| , | ||
| , | Website down Jul 2022 - Nov 2022 | |
| , | Now Sandia Biotech | |
| , | Bought by MorphoSys, Oct 2010, $26.5M | |
| , | Renamed Hansa Biopharma | |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| , | Renamed Reactive Biosciences | |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| CanSino Biologics | Tianjin, China | Vaccines |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| , | Acquired by Worg Pharmaceuticals, Aug 2021 | |
| , | Renamed Atopia Therapeutics | |
| Carver Biosciences | Boston, MA | CRISPR/Cas13-based Technologies |
| , | Renamed Anteris Technologies, Jun 2020 | |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| , | ||
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| , | Renamed Tridien Medical, May 2010 | |
| Nanosonics | Sydney, Australia | Ultrasound |
| , | Website down Aug 2024 - Feb 2025; aka DualityBio | |
| , | Now Xbrane Biopharma | |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech | |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| , | Product Acquired by Forest Labs | |
| TigaTx | Boston, MA | Engineered IgA |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| , | Merged into Precipio, Jun 2017 | |
| , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals | |
| , | Shut down Nov 2021 | |
| , | ||
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| , | Acquired by Supernus, Oct 2018, $15M + $168M milestones | |
| , | Acquired by Clinipace | |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 | |
| Factor Bioscience | Cambridge, MA | RNA Reprogramming Technology |
| |
Emeryville, CA | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| , | Website down Jul 2023 - Dec 2023 | |
| , | Renamed Fluid Biomed, late 2022 | |
| , | Renamed Biosavita | |
| Bayer | Barcelona, Spain | Small Molecules |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| , | Website under construction, Nov 2016-Feb 2018 | |
| Dren Bio | Foster City, CA | Protein Therapeutics |
| , | Website down Aug 2019 - Oct 2019 | |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| Defined Bioscience | San Diego, CA | Cell culture reagents and media from defined sources |
| , | Acquired by EyeGate Pharma, Mar 2016, stock | |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| , | Acquired by Genzyme, Feb 2004 | |
| , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator | |
| , | Renamed Sotera Digital Health | |
| , | Bought by Celgene, Jan 2018, up to $7B | |
| , | Acquired by Caris Life Sciences, May 2019 | |
| , | Gone by 2019; fka Accurexa | |
| , | Acquired by Adaptive Biotechnologies, Jan 2015 | |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| , | Acquired by Predictive Oncology, Dec 2021 | |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| , | Sold Assets late 2020 | |
| WCG Clinical | Princeton, NJ | Clinical Trial Services |
| , | Renamed NapticBio, Jan 2018 | |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| , | Acquired by an oil company, folded into Santalis, Jun 2015 | |
| , | Funding in 2014, no website or news since then as of Aug 2021 | |
| , | CEO moved on, still on website four years later | |
| , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 | |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| , | Out of business 2013 | |
| , | Merged with New England Peptide after PE buyout, Dec 2019 | |
| Hasten Pharma | Hefei, China | Small Molecules |
| Elypta | Solna, Sweden | Liquid Biopsy |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| , | Acquired by Oxford Immunotec, Jul 2016, $22M | |
| , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 | |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| , | ||
| , | Acquired by Nutrasource Diagnostics | |
| , | Not sure if active Sep 2020 - Dec 2020 | |
| , | Website down Jul 2023 - Dec 2023 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Closed Nov 2018; fka InnovaTID | |
| , | Terminated clinical studies to focus on diagnostics in 2009, but no other info | |
| , | Bankrupt 2011 | |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| miRNA Scientific | Rensselaer, NY | RNA Profiling Technology for Cancer Diagnosis |
| , | Renamed Empatica, Jun 2014 | |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| , | Website down Jan 2024 - Jul 2024 | |
| Mahana Therapeutics | San Francisco, CA | App for IBS |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| , | Now Sunovion | |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| The Micron Group | Centurion, South Africa | Consulting |
| , | Bought by Shire, Feb 2015, $70M +$175 milestones | |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| , | Website down Mar 2023 - Sep 2023 | |
| , | Renamed Skye Bioscience | |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| , | Everyone gone Aug 2022 | |
| , | Website down May 2023 - Dec 2023 | |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| , | ||
| Castle Creek Biosciences | Exton, PA | Small molecules |
| , | Sold main nutraceutical product | |
| , | Bought by PL Developments | |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| , | ||
| , | Filing Chapter 7 Bankruptcy, Jul 2019 | |
| , | Acquired by Cybin, Aug 2023 | |
| , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. | |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| , | Website down Sep 2024 - Feb 2025 | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | No website Jul 2021 - Jul 2024 | |
| Cellenion | Tempe, AZ | Single Cell Testing |
| , | ||
| , | Website down Jan 2020 - Jul 2020 | |
| , | Acquired by Charles River Labs, Jun 2016 | |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Bankrupt | |
| Synbiosis | Cambridge, UK | Colony counting instruments |
| , | Renamed Facet Medical Technologies | |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 | |
| , | Acquired by Royalty Pharma | |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| , | Renamed Talphera, Jan 2024 | |
| , | Auctioning off assets, Aug 2020 | |
| , | Acquired by Exact Sciences, May 2021, $30.6M | |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| , | Bought by Smith & Nephew, Oct 2017 | |
| , | Acquired by Essential Pharma, Apr 2024 | |
| , | Merged with Invicro to become Perceptive, Sep 2024 | |
| , | Gone Jul 2015 | |
| , | ||
| , | Bought by Neogen | |
| , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 | |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Ingenza | Roslin, UK | Contract Manufacturing |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| , | Professor side project, old and no news 2018-2024 | |
| , | Acquired by Quest Diagnostics, Mar 2011, $671M | |
| , | Gone, 2020 | |
| Genestack | Cambridge, UK | Genomics operating system |
| , | Gone | |
| , | Website gone Oct 2021 | |
| , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 | |
| , | Website down May 2024 - Sep 2024 | |
| Getinge | Rastatt, Germany | Medical Technology |
| , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical | |
| , | Renamed Actylis, Sep 2022 | |
| , | Bought by Horizon Discovery, Jul7 2017, $85M | |
| RedShiftBio | Boxborough, MA | Analytical instrumentation for life science research |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| , | Seems inactive Feb 2021 | |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Applied DNA Sciences | Stony Brook, NY | DNA Security Tags |
| Spectral Service | Köln, Germany | Spectroscopy Lab |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| InnoN | Seoul, Korea | Biologics, Small Molecules |
| Dipharma | Baranzate, Italy | APIs, Generics |
| , | Closed down after being convicted of Federal & CA state violations | |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| TRIFARMA | Milan, Italy | APIs |
| , | Gone 2006 | |
| , | Acquired by Within3, Apr 2021 | |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| , | Website down Nov 2023 - Mar 2024 | |
| , | Website Gone, Feb 2018 | |
| OverT Bio | New York, NY | Cell Therapy |
| , | Acquired by Hologic, $125M, Oct 2018 | |
| , | Bought by Telix Pharmaceuticals, Jan 2017 | |
| DDL | Edison, NJ | Device Testing |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| , | Acquired by Corcym, Apr 2023 | |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Maxwell Biosciences | Austin, TX | Antivirals |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| , | Acquired by YM BioSciences, May 2006 | |
| Sharp | Conshohocken, PA | Contract clinical trial services and commercial packaging services |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Acquired by Lannett, Jun 2015 | |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| , | Bought by NantCell, Aug 2017, $360M | |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Regulus Therapeutics | San Diego, CA | MicroRNAs |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| Artialis | Liège , Belgium | Biomarker-based Solutions for Clinical Studies |
| , | Site down, Aug 2018 | |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| , | Website down Jun 2020 | |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| , | Acquired by Pfizer, Oct 2022, $5.4B | |
| Atomwise | San Francisco, CA | AI for Drug Discovery |
| , | Bought by Bio-rad | |
| , | Bankrupt, 2013 | |
| Helix | San Mateo , CA | Genetic Testing |
| RapidPulse | Miami, FL | Cyclic Aspiration System for Ischemic Stroke |
| Kaléo | Richmond, VA | Drug Delivery Technology |
| , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 | |
| , | ||
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| , | Acquired Dimerix, Jul 2015, took name | |
| , | Acquired by Cargill, Apr 2015 | |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Website Gone | |
| Carmot Therapeutics | Berkeley, CA | Small Molecule Drug Discovery |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| , | Renamed Incite Genomics, Oct 2023 | |
| , | Bought by Qualitest | |
| Silk Road Medical | Sunnyvale, CA | Carotid artery diseases treatments |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| , | Bought by Actavis, Jul 2014, $25B | |
| , | ||
| MeiraGTx | London, UK | Gene Therapy |
| , | Changed to Igenbio | |
| , | Website down Nov 2023 - Mar 2024 | |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| , | ||
| , | Shell company Aug 2019 | |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| , | Renamed Anchiano Therapeutics, Aug 2018 | |
| , | Bought by Cytomedix Feb 2012 | |
| , | Nothing going on 2015-2021, everyone has University jobs | |
| Salvat | Barcelona, Spain | Small Molecules |
| Qpex Biopharma | San Diego, CA | Anti-infectives |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| , | Gone, Founder took job with Oculus VR | |
| , | Shut down, Apr 2021 | |
| , | Acquired by KCI, Oct 2013, $485M | |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| , | Acquired by Grunenthal, Jul 2024, $250M | |
| , | Acquired by MaxCyte, Jan 2025 | |
| , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 | |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| , | Founded 2015, no website Aug 2021 | |
| Brii Biosciences | Shanghai, China | Bringing medicines to Chinese market |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| , | Website Gone 2-22-14 | |
| , | Gone Jun 2020 | |
| , | Bought by Abzena, Sep 2015, $8.4M | |
| , | Website down Aug 2022 - Jan 2023 | |
| , | Merged with Olerup, Jan 2017 | |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| , | Acquired by Bimini HealthTech, Jun 2020 | |
| BioBam | Valencia, Spain | Bioinformatics Software |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| , | Merged with ERT, 2021 | |
| , | Acquired by DermBiont | |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| , | Renamed GC Pharma | |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| , | ||
| , | Bought by Sun Pharma | |
| , | Sold Assets to Thor Labs | |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assey Development |
| , | No news since 2013 as of Aug 2023 | |
| Triumvira Immunologics | Austin, TX | Adoptive Immunotherapy |
| Integer | Salem, VA | Medical & Surgical Devices |
| , | Bought by Perkin-Elmer 2017 | |
| , | Assets acquired by The Genetics Company, Mar 2003 | |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares | |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| , | Bankrupt, assets acquired by MicroGEM Apr 2016 | |
| , | Renamed Prolytix, Feb 2022 | |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Ventris Medical | Newport Beach, CA | Tissues |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| , | Licensed most assets. Virtual company, just gets money from licensing | |
| , | Renamed Pharmanest | |
| , | Became part of Endo, 2010 | |
| , | Acquired by Cytocom via Reverse Merger, Oct 2020 | |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Pyramid Labs | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| , | Now Bostal Pharma, Feb 2025 | |
| , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 | |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| , | Acquired by Bausch + Lomb, Jan 2023 | |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| , | Employees all left, Linkedin page gone as of Nov 2023 | |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| AMS Biotechnology | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned | |
| , | Renamed CorneaGen, Apr 2018 | |
| , | Website down May 2021 - Sep 2021 | |
| , | ||
| , | Acquired by Vir Biotechnology, May 2018 | |
| , | Shut Down Dec 2019 | |
 |
Morrisville, NC | Catalent | Analytical Services, Inhalation Product Development |
| , | No info since 2012, never registered in MA | |
| Saptalis | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| , | Bought by Stryker, Nov 2020, $4.7B | |
| , | Renamed Core Oncology | |
| , | Renamed TeneoBio, Dec 2015 | |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| , | Switched to beauty products | |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones | |
| , | Acquired by Vistagen, Feb 2023 | |
| , | Apparently Gone | |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 | |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| , | Acquired by Portage Biotech, Jul 2022 | |
| , | Shut down Mar 2024 | |
| , | Acquired by BMS, 1986 | |
| , | Bought by BTG plc, Sep 2008, £218M | |
| , | Dissolved. 2015? | |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| , | Not registered in CA as of Aug 2019 - Jun 2022 | |
| Vertos Medical | Aliso Viejo, CA | Minimally invasive patented procedure for lumbar spinal stenosis |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| TianTi Biotherapeutics | Suzhou, China | Antibody Therapeutics |
| , | Changed name to Ardea Biosciences 2006 | |
| , | Acquired by BioNTech, Nov 2023 | |
| , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M | |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| , | Absurd website has to be gone | |
| , | Renamed Evive Biotech, Jun 2020 | |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Xellia Pharmaceuticals | Copenhagen, Denmark | Specialty Pharmaceuticals |
| Cellino Biotech | Cambridge, MA | Cell therapies |
| , | Gone | |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| Koelis | Meylan, France | Prostate Biopsy System |
| , | ||
| Collagen Solutions | Eden Prairie, MN | Collagen |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| Buzzard Pharmaceutical | Stockholm, Sweden | IL-1 Inhibitor |
| , | Acquired by Philips, Feb 2021; fka CardioNet | |
| , | Apparently Gone | |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 | |
| , | Website Gone | |
| , | Acquired by Pace Analytical, Dec 2020 | |
| , | Merged with Oncogenex | |
| , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 | |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Recipharm | Pessac, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Telo Genomics | Toronto, ON | Diagnostics |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| Flightpath Biosciences | Berkeley, CA | Reformulations for Tick-borne Diseases |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| , | Acquired by STEMCELL Technologies, Jan 2024 | |
| Collagen Solutions | Seoul, Korea | Collagen |
| Inicure | Göteborg, Sweden | Small Molecule FPR Agonists |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| , | Bought by Harvest One Cannabis, Mar 2019 | |
| , | Shut down Dec 2024 | |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| , | Acquired by Getinge, Jan 2020 | |
| , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. | |
| , | ||
| Pace Analytical | Ormond Beach, FL | Analytical Testing |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| , | Renamed Egenix, 2002 | |
| , | Acquired by Sun Pharma, Jan 2019 | |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| mibe Arzneimittel | Brehna, Germany | Generics |
| , | Company was either renamed or reformed as Kaleido, 2017 | |
| , | Acquired by Soluble Therapeutics, Oct 2014 | |
| , | Renamed Migenix | |
| , | Renamed Celsius Therapeutics, Jan 2018 | |
| , | Not an active CA business, Sep 2019 | |
| , | Acquired by Organon, Dec 2021, $954M | |
| , | Website down Aug 2022 - Jan 2023 | |
| , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 | |
| , | Renamed Vyne Therapeutics, Sep 2020 | |
| Quiver Biosciences | Cambridge, MA | Precision Genetic Medicine Services |
| , | Website down Jan 2023 - Jul 2023; Inside ATAI for now | |
| PharmaLex | Zaragoza, Spain | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| TianTi Biotherapeutics | Woburn, MA | Antibody Therapeutics |
| , | Renamed STgen Bio, Apr 2022 | |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| , | Shut down Jul 2022 | |
| , | Renamed Corxel Bio, Oct 2024 | |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Celyad Oncology | Mont-Saint-Guibert, Belgium | CAR T Therapies for Cancer |
| Inhibikase Therapeutics | Atlanta, GA | Therapeutic Vaccines |
| , | Dissolved, Feb 2021 | |
| , | Renamed Sonoma Pharmaceuticals, Dec 2016 | |
| , | Renamed Svar Life Science, 2018 | |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| , | Shut down, Mar 2017 | |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| , | Renamed CellCarta, Feb 2021 | |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| , | ||
| , | Website down Jul 2021, came back as a Covid symptom checker | |
| , | Website down Mar 2024 - Jul 2024 | |
| , | Renamed Immunocodex, Feb 2024 | |
| , | Renamed Xel Pharmaceuticals | |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| , | Website down Sep 2021 - Jan 2022 | |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| , | ||
| , | Gone, Apr 2017 | |
| , | Bought by Par Pharmaceutical | |
| , | Seems like a testing lab | |
| , | Acquired by Lilly, May 2018 | |
| , | Inactive Jun 2022 | |
| , | ||
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| , | Acquired by Abbott, Sep 2021 | |
| , | Website down Aug 2022 - Jan 2023 | |
| , | Gone | |
| EndLyz Therapeutics | , | Parkinson's Therapies |
| InnoSkel | Biot, France | Therapies for Rare Skeletal Diseases |
| Octapharma | Springe, Germany | Plasma Products |
| , | Business license revoked Oct 2019, no filings since 2016 | |
| , | Shut down early 2021 | |
| , | Acquired by Biofocus, Jun 2001 | |
| Thousand Oaks Biopharmaceuticals | Shanghai, China | Biologics CDMO |
| , | Renamed Mycovia Pharmaceuticals | |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| , | Acquired by Alexion, Jan 2020, $930M | |
| , | Website gone 2-5-15 | |
| , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. | |
| , | Website redirects to Celling Biosciences, Jan 2016 | |
| Biomax Informatics | Planegg, Germany | Genome Analysis |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Pluto Biosciences | Denver, CO | Collaborative Life Sciences Platform |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| , | Acquired by Frontage Labs, Apr 2018 | |
| , | Renamed Fresh2, May 2023 | |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| , | Renamed Hervolution Therapeutics, Sep 2023 | |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Kisbee Therapeutics | Cambridge, MA | Recombinant lipoproteins to target the core biological systems underlying neurodegenerative diseases |
| Abterra Biosciences | San Diego, CA | Antibody Discovery & Services |
| , | Acquired by Stryker, Oct 2013, $30M | |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Serimmune | Goleta, CA | Antibody Biomarkers |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| DNA Worldwide | Frome, UK | DNA Testing |
| , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 | |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Intact Genomics | St. Louis, MO | PCR kits |
| , | Merged with Celldex 2005 | |
| , | Liquidating Dec 2020 | |
| , | Assets acquired by Millipore, 2009 | |
| , | Closed, May 2007 | |
| , | Shut down Dec 2023 | |
| Hovione | Macau, China | Contract Manufacturing |
| , | Shut down, Dec 2015 | |
| , | Part-time CEO, seems nonserious Feb 2023 | |
| , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B | |
| , | Confirmed gone by co-founder | |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| , | Gone Mar 2006 | |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| NanoCell Therapeutics | Wayne, PA | Gene Therapy |
| , | Doesn't seem active as of Mar 2015 | |
| , | Assets acquired by STRATA Skin Sciences | |
| , | Acquired by Cerenis Therapeutics, Nov 2017 | |
| , | Website gone Mar 2023 | |
| , | ||
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| , | Bought by Procyon Biopharma, Jun 2005, $3.5M | |
| , | Website down Aug 2023 - Feb 2024 | |
| , | Renamed Caravan Biologix | |
| ANS Biotech | Riom, France | Drug Screening, Consulting, Services |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| , | Renamed Alvea | |
| , | Acquired by Envision Healthcare, Mar 2017 | |
| , | Website down Jun 2021 - Oct 2021 | |
| , | Acquired by GSK, Jul 2022, $1.9B | |
| , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery | |
| , | Operations acquired by UCB Pharma, Feb 1999 | |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Gilead | Foster City, CA | Small Molecules |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| , | Renamed Avanos Medical, Jun 2018 | |
| , | Closing down Jun 2023 | |
| , | Acquired by UCB, 2006, €4.4B | |
| , | Website down Jan 2023 - Jul 2023 | |
| , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 | |
| , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals | |
| , | Bought by Alcon, bought by Novartis | |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Acquired by Fisher Scientific, Aug 2005, $49M | |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 | |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| , | Effectively renamed Allegiant Health | |
| Quartzy | Hayward, CA | Lab Management Software |
| Leading Pharma | Fairfield, NJ | Generics |
| , | Website down Feb 2023 - Jul 2023 | |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| , | Acquired by Novartis, Jan 2024 | |
| , | Gone 2012 | |
| , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M | |
| , | Website Gone, execs gone | |
| , | ||
| Medtronic | Mansfield, MA | Medical Devices |
| , | Accused by SEC of being a sham. Probably is. | |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Previse | Halethorpe, MD | Cancer Diagnostics |
| , | Bought by Merck, Jan 2020, $2.7B | |
| , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones | |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| , | Moved from San Francisco, sole employee is CEO of new company | |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| , | ||
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| ProSci | Poway, CA | Antibodies, etc. |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Real Research | Krakow, Poland | 3D Cell Culture |
| , | No real employees, no website Nov 2019 - Dec 2020, CEO gone | |
| , | ||
| , | Gone 2013 | |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| , | Renamed Rakuten Medical, Mar 2019 | |
| , | Acquired by Ellex, Jan 2014 | |
| , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 | |
| , | Switched to writing | |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| , | Website copyright 2005 as of Mar 2021 | |
| , | Website gone Jan 2019, Chinese company | |
| , | Now Adocia | |
| , | ||
| ClinChoice | Fort Washington, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| , | Acquired by Hillrom, Sep 2021 | |
| , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 | |
| , | Shut down Dec 2020 | |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| , | Merged with Midatech Pharma, Jun 2015 | |
| , | Changed name to Cascadian Therapeutics, Jun 2016 | |
| , | Seems like they were just a company that sought an ANDA to sell on | |
| , | Changed name to Avalyn Pharmaceuticals, Jul 2017 | |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| , | Gone | |
| , | Acquired by Cardinal Health, May 2004 | |
| , | Renamed Turning Point Therapeutics, Nov 2018 | |
| Normunity | West Haven, CT | Immune Normalizer Therapies |
| , | Gone Apr 2018 | |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| , | Website down Nov 2024; business filings late Jan 2024 | |
| , | Acquired by Pfizer early 2004 $1.3B | |
| , | ||
| , | Acquired by Tosoh Biosciences, Oct 2021 | |
| , | Acquired by Roche from Roivant, Dec 2023 | |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences | |
| , | Acquired by Sartorius, Dec 2022 | |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| , | Gone | |
| , | Acquired by Kemin Jun 2009 | |
| , | Doesn't seem serious; Single-person company?, Dec 2019 | |
| , | No website. Oklahoma based, Blood pump | |
| Stada | Vršac, Serbia | Generics |
| , | Acquired by Pernix | |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| , | Renamed Sharp Therapeutics, Feb 2021 | |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| , | Acquired by Kiniksa, May 2019 | |
| , | ||
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| , | Renamed Axcella Therapeutics | |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| , | Renamed vivoVerse, late 2022 | |
| , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 | |
| , | Bankrupt 2012 | |
| , | Acquired by Active Motif, Nov 2010 | |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| , | No news 2021 - Feb 2025, never registered in MA | |
| , | ||
| , | Closed 2013 | |
| , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 | |
| , | Acquired by Genoptix Sep 2012 | |
| , | Website gone Jul 2018 | |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| , | Renamed Amgen | |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| , | Website gone Jun 2020 - Mar 2021 | |
| , | No updates since 2014, no employees on LinkedIN | |
| , | Assets Acquired by MedGenome, Feb 2016 | |
| , | Winding down Jun 2024 | |
| BioTherapeutics Inc | Blacksburg, VA | Small Molecules |
| NeoClone | Madison, WI | Antibody discovery & development |
| , | Renamed Apollomics, Jan 2019 | |
| ClinSmart | Newtown, PA | Clinical Research |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Affilogic | Nantes, France | Affinity proteins, Antibodies |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| , | Acquired by Codman Neuro, Apr 2017 | |
| , | Bought by Vir Biotechnology, Aug 2017 | |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| , | Website gone Aug 2024, not registered in MA | |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones | |
| Avadel Pharmaceuticals | Dublin, Ireland | 505(b)(2) product |
| , | Website down Jan 2019 - Apr 2019 | |
| , | Technology purchase by Aerie, Oct 2017 | |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Aenova | Starnberg, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Acquired by Oxford Biomedica Mar 2007 | |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| , | Merged with Arc Bio to become Cantata Bio, Jun 2022 | |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 | |
| , | Renamed Elutia, Sep 2023 | |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| , | Bought by DePuy | |
| , | Website down Oct 2023 - Mar 2024 | |
| Protein Metrics | Boston, MA | Protein characterization software |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| |
Oro Valley, AZ | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| , | Gone | |
| , | Acquired by Terumo, Nov 2019 | |
| , | Acquired by Marijuna company, Nov 2011 | |
| , | Shut down Dec 2023 | |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| , | Website taken over May 2020 | |
| , | Bought by Qiagen, Jun 2014 | |
| , | Acquired by Chimerix, Jan 2021, $78M | |
| , | Acquired by Novo Nordisk, Oct 2022, $1.1B | |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| KMC Systems | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Theramex | London, UK | Women's Health |
| , | Acquired by eurofins, Jun 2017 | |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| , | ||
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| , | Bought by Huvepharma, Mar 2014 | |
| Acrux | West Melbourne, Australia | Drug Delivery |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| Becton Dickinson | Franklin Lakes, NJ | Lots of Biotechnology Products |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| , | ||
| , | Acquired by AskBio, Aug 2019 | |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| , | Stopped research Jan 2025 | |
| , | Website down Dec 2022 - Apr 2023 | |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| , | Renamed Triana Biomedicines, Feb 2022 | |
| , | Website down, employees gone Jun 2024 | |
| , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems | |
| Rheonix | Ithaca, NY | Microfluidics for Molecular Diagnostics |
| , | Closed | |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| , | Liquidated Apr 2023 | |
| , | Acquired by Fitzgerald Industries, 2005 | |
| , | Bought by Wyeth 1994 | |
| miRNA Scientific | Tel Aviv, Israel | RNA Profiling Technology for Cancer Diagnosis |
| , | ||
| , | Merged into Sunbird Bio, Aug 2023 | |
| , | Acquired by Hologic 2012 | |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| , | Website hijacked Oct 2020 | |
| , | Bought by Astellas | |
| , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? | |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| Norgine | Madrid, Spain | Specialty Pharma |
| , | Website down Nov 2023 - Apr 2024 | |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| , | Bankrupt Feb 2020 | |
| , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva | |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| , | Shut Down Feb 2019 | |
| TCG GreenChem | Ewing, NJ | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Website down Mar 2024 - Jul 2024 | |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| , | Renamed Cellipoint Bioservices | |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| , | Bankrupt, 2016 | |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Acquired by Boston Scientific, Feb 2018 | |
| , | ||
| , | Website down Mar 2023 - Dec 2023 | |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 | |
 |
Reading, UK | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Seems gone | |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| , | ||
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| , | Seems gone Apr 2022 | |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| , | Penny Stock, no idea what happened | |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| , | Acquired by Amura Ltd | |
| Biomea Fusion | Redwood City, CA | Small Molecules Targeting Cancer |
| , | Company founder/employee all moved on | |
| Samplix | Birkerød, Denmark | Droplet-based, PCR-free Amplification |
| , | Bankrupt 2007 | |
| , | Acquired by Alvogen, Mar 2016, $300M | |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| , | Merged with British Biotech, Mar 2003 | |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| Tecomet | Wilmington, MA | Implant Components |
| , | Sold off product | |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| GSK | Middlesex, UK | Small Molecules, Vaccines, Biologics |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| , | Website Gone 2-15-14. No info on what happened. | |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| , | Shutting down Nov 2020 | |
| , | Sold lone asset to PTC Therapeutics, Apr 2017 | |
| , | ||
| , | Acquired by Smith & Nephew, Apr 2019, $660M | |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 | |
| , | Bought by Cell Biosciences | |
| , | Acquired by Takara Bio Jul 2014 | |
| , | Website down Nov 2022 - Mar 2023; fka Antigen Express | |
| , | ||
| , | Website down Jan 2023 - Sep 2023 | |
| , | Bought by Celgene, Apr 2014, $710M | |
| , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 | |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Coating Place | Verona, WI | Drug Delivery Services |
| , | Bought by LabCorp, 2008 | |
| Novotech | Hong Kong, China | Clinical Research |
| , | Acquired by Viva Biotech, Aug 2020, $367M | |
| , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 | |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| , | Website down Feb 2024 - Mar 2024 | |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences | |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx | |
| , | Renamed Mendus, Jun 2022 | |
| , | Acquired by Pacific Biosciences, Sep 2021, $800M | |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| , | Website gone, Apr 2018 | |
| Stago | Tianjin, China | Diagnostics |
| , | ||
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Axplora | Pompey, France | CDMO Services |
| , | Bought by Covidien, Jun 2009, undisclosed terms | |
| , | Renamed Epix Pharma | |
| , | ||
| , | Renamed Farcast Biosciences, 2019 | |
| , | Gone | |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| , | Bought by Zoetis, Jul 2018 | |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| , | Acquired by Sun pharma Sep 2015 | |
| , | Broken up and sold off, Sep 2014 | |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Abbott | Clonmel, Ireland | Stents |
| , | Renamed Nuwellis, May 2021 | |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| , | ||
| , | Seem to have changed their name to Cmxtwenty | |
| , | Gone. No info | |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| , | Website gone | |
| , | ||
| , | Changed name to Aptose Biosciences, Aug 2014 | |
| , | Acquired by PTC Therapeutics, Jun 2020 | |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| , | Rebranded IMV, 2018 | |
| InterAx Biotech | Villigen , Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| , | Closed due to complicated biology | |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| , | No website Mar 2020 | |
| , | Acquired by Fisher, Aug 2004 | |
| , | Renamed sb-Peptide | |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| LexaMed | Toledo, OH | Life Science Consulting |
| , | Acquired by Biotie | |
| , | Gone, 2019 | |
| , | Merged with Espero Pharma, Mar 2017 | |
| , | Acquired by BioNTech, Nov 2021 | |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| , | Gone | |
| , | Website gone | |
| , | Renamed Alyve Medical, Apr 2022 | |
| , | Changed named to Ionis Pharmaceuticals, Dec 2015 | |
| , | Renamed Bioheal Therapeutics, Jan 2023 | |
| ProSolus | Miami, FL | Formulate, develop, and manufacture high-barrier-to-entry transdermal drug delivery products |
| Aerogen | Galway, Ireland | Nebulizers |
| , | Acquired by Celgene 2007 | |
| Lupin | Blue Bell, PA | Generics |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Sylentis | Madrid, Spain | RNAi Treatments |
| , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care | |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| , | Website gone Apr 2019 | |
| Apollomics | Foster City, CA | Cancer medicines |
| , | No news 2017-2022 | |
| , | Acquired by Biogen, Jan 2007 | |
| , | Winding down May 2024; LI page gone Nov 2023 | |
| , | Renamed Heidelberg Pharma Oct 2017 after acquiring them | |
| Medtronic | Minneapolis, MN | Medical Devices |
| Validation Associates | Herndon, VA | Validation Consulting |
| Metalytics | Cary, NC | Mapping of metabolic reaction rates in industrially relevant cell factories |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| , | Shut Down Prior to Aug 2014 | |
| 3T Biosciences | South SF, CA | TCR Therapies |
| Univfy | Los Altos, CA | IVF reports |
| , | Website down Feb 2022 - Jul 2022 | |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| , | Only employee gone 2018 | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Acquired by Ginkgo Bioworks, Oct 2022 | |
| |
Carugate, Italy | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Gone Jul 2010 | |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| , | No news since 2006 lawsuit | |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 | |
| , | All employees gone, no info | |
| , | Website down Oct 2022 - Apr 2023 | |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| , | Gone? | |
| NextPharma | Limay, France | Contract Research & Development |
| Stago | Clarkston, GA | Diagnostics |
| , | Bought by Actinogen, Aug 2014, $5.75M | |
| , | Website gone Jul 2020 | |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Starton Therapeutics | Paramus, NJ | Transdermal Delivery Technology, 505(b)(2) |
| , | ||
| , | Merged into Sphingotec, May 2018 | |
| , | Trouble with contaminated products, gone | |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 | |
| , | Merged with Nova Satra, Aug 2019 to become Inex Innovate | |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Atopia Therapeutics | Geneva, Switzerland | Asthma & Allergy Treatments |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| , | Acquired by Tornier, Feb 2007 | |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| , | Website down Apr 2021 - Sep 2021 | |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| , | Renamed Cefaly | |
| , | Website down Mar 2023 - Oct 2023 | |
| |
Frankfurt, Germany | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Seems gone, Website down Jan 2024 - Jul 2024 | |
| , | Acquired by Cytotheryx, Feb 2023 | |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| Prokarium | London, UK | Oral Vaccines |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics | |
| , | ||
| , | Assets Acquired by LumiThera Diagnostics | |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| , | ||
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| , | Website down Apr 2024 - Aug 2024 | |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| , | No website Jan 2020 - Jul 2024 | |
| , | Acquired by Insmed in reverse merger, May 2000 | |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Acquired by Merck 2011 | |
| , | Changed name to Helomics, Nov 2014 | |
| , | Bankrupt, Jun 2017. Bought by Acessa Health. | |
| , | Website taken over, Aug 2024 | |
| , | Acquired by Kindeva Drug Delivery, Jan 2024 | |
| , | Shut down 2018 | |
| , | Gone, Dec 2014 | |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| , | Bought by J&J, Nov 2015 | |
| , | Acquired by Horizon Pharma, Dec 2015, $510M | |
| , | No updates 2014-2023 | |
| , | Bought by Sandoz Jul 2012, $1.525B | |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | ||
| , | Acquired by Karo Pharma, Sep 2019 | |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| Owkin | New York, NY | AI for Medical Research |
| , | ||
| , | Acquired by Stryker, Jul 2018, $9M | |
| , | Acquired by Roche, Nov 2001 | |
| , | Dated website, no updates Sep 2019 - Feb 2025 | |
| , | Bankrupt | |
| Lean Biologix | Norfolk, MA | Consulting |
| , | Bought by Smith & Nephew | |
| , | Renamed Momentum Biotechnologies, Aug 2023 | |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| , | Merged into Luc Therapeutics, Mar 2017 | |
| , | Rolled into parent, SMC | |
| , | Gone, Apr 2016? | |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| , | Renamed Adastra Pharmaceuticals, Jan 2019 | |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Ottobock | Duderstadt, Germany | Prosthetics |
| , | ||
| CO.DON | Teltow, Germany | Cell Therapies |
| , | Website gone, Dec 2018, Founder is also with a new company | |
| , | No website Sep 2021 - May 2023 | |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Corza Medical | Somerset, UK | Surgical Devices |
| , | Shut down, Dec 2017 | |
| , | Seems gone Jun 2022 | |
| , | Website down Dec 2020 - Feb 2021 | |
| , | Rebranded as Hillrom, May 2019 | |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| KARL STORZ Endoscopy-America | Singapore, Singapore | Endoscopy |
| pH Pharma | Seongnam, Korea | Small Molecules, ADCs |
| , | ||
| , | ||
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| , | Bought by Teva 2004 | |
| , | Website down Aug 2024 - Feb 2025 | |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| , | No business filings since 2011 | |
| , | ||
| , | Gone June 2017 | |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| , | Renamed Cirius Therapeutics | |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| Neocis | Miami, FL | Dental Surgery Robots |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| Mathys Medical | Bettlach, Switzerland | Orthopedic Devices |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Genactis | Mougins, France | Pharmaceutical Consulting |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| , | Acquired by Smith & Nephew, May 2014 | |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| , | Acquired by Altasciences, May 2021 | |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| , | Renamed Karuna Therapeutics | |
| Bionsight | Seoul, Korea | Database For Research |
| , | Closed Feb 2009, assets bought by Aduro Biotech | |
| Drugabilis | Villejust, France | Drugability Services |
| Neumous | Cheongju, Korea | Ultrasound Medical Devices |
| , | Website down Mar 2020 - Jul 2020 | |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Anju Life Sciences Software | Tempe, AZ | Life Sciences Software |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| , | Changed name to Leadient Biosciences, Feb 2017 | |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| , | Renamed VaxCyte | |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| , | Acquired by Thermo Fisher, May 2010, $260M | |
| , | Business filings late, Sep 2022 - Feb 2025 | |
| Becton Dickinson | Canaan, CT | Lots of Biotechnology Products |
| , | Bought by Intrexon Dec 2013 | |
| , | Acquired by Acino, 2004 | |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| CMD Medtech | Columbus, OH | Medical Device Development |
| , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 | |
| , | Acadia spinout. No info since 2006 founding. Presume defunct | |
| Getinge | Plewiska, Poland | Medical Technology |
| , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics | |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Afaxys | Charleston, SC | Women's Health |
| , | Acquired by Adnexus, Nov 2024 | |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Amador Bioscience | Hasselt, Belgium | Consulting, Lab Service, Clinical Trial Management |
| , | No news 2015 - Nov 2024 | |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| , | Renamed Ocunexus | |
| , | Website down Mar 2021 - Aug 2021 | |
| rhealth | Bedford, MA | Diagnostics |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| , | Bought by Amgen May 2019 | |
| , | Bought by Labcorp | |
| , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones | |
| , | No website. | |
| , | Acquired by Allergan, Jan 2016, $90M | |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| Valerius Biopharma | Basel, Switzerland | Biosimilars |
| , | Shut down 2018 | |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| , | Shut down Aug 2020 | |
| , | Acquired by Clinigen, Nov 2017 | |
| , | Shut down Dec 2020 | |
| , | Acquired by Covis Pharma, Nov 2020 | |
| , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock | |
| , | Gone | |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM | |
| , | Acquired by Citoxlab, Oct 2017 | |
| Attralus | Naples, FL | Amyloidosis Treatments |
| Stada | Belgrade, Serbia | Generics |
| , | Website Gone 9-12-13 | |
| , | SBIR, Presumed defunct | |
| , | Website down May 2023 - Sep 2023 | |
| , | Renamed BioNano Genomics | |
| TetraScience | Boston, MA | Scientific Cloud Software |
| , | Subsidiary of Besins | |
| , | Shut down early 2023 | |
| , | Website Gone, Nov 2016 | |
| , | No website Oct 2019 - Aug 2021 | |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Merged with Ovation.io, Sep 2024 | |
| , | Licensed drug rights to Alopexx. Shell company | |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| , | Only person listed on website doesn't even list this job on LI profile | |
| , | Acquired Lake Region Medical $390M Mar 2014, took on their name | |
| , | Renamed TrueBinding | |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| , | Acquired by FujiFilm, Dec 2011 | |
| , | No website, business suspended by NC | |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| , | Renamed Astria Therapeutics, Sep 2021 | |
| , | Acquired by Symansis, Jun 2008 | |
| , | Changed name to CHF solutions, May 2017 | |
| , | ||
| Alternative Bio | , | |
| Lacer | Barcelona, Spain | Small Molecules |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| |
Basel, Switzerland | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| KARL STORZ Endoscopy-America | El Segundo, CA | Endoscopy |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| , | ||
| , | Acquired by Sun Pharma, Mar 2023 | |
| , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 | |
| , | Merged with AskBio, Dec 2020 | |
| , | ||
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Lavipharm | Peania, Greece | Small molecules |
| , | Acquired by Iuvo BioScience, Jan 2024 | |
| , | Website down May 2021 - Sep 2021 | |
| , | ||
| , | Website taken over | |
| , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 | |
| , | Merged with United Neuroscience, Apr 2021 | |
| , | ||
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma | |
| Kine Sciences | Seoul, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| , | Changed name to Opiant Pharmaceuticals, Feb 2016 | |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 | |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| , | Renamed Manus Bio, Jun 2018 | |
| Recipharm | Manheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Website down Apr 2022 - Jul 2022 | |
| , | Bought by St Jude Medical Aug 2014, $200M | |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 | |
| Vetter | Langenargen , Germany | Aseptic Filling |
| , | Assets acquired by Invisio Medical, Feb 2018 | |
| , | Seems inactive Feb 2024 | |
| , | Only employee doesn't list on long LI profile | |
| , | Renamed Factorial Biotechnologies | |
| , | Acquired by Sofie Biosciences, Sep 2017 | |
| Proimmune | Oxford, UK | Immunology research products |
| , | ||
| Biomica | Rehovot, Israel | Microbiome Therapies |
| , | Business filings late May 2023 - Feb 2025; no news 2018-2025 | |
| , | Website Gone | |
| , | Bought by Par Pharmaceuticals | |
| , | Gone 2012 | |
| Akoya Biosciences | Marlborough, MA | Barcoded Staining Antibodies |
| , | Shut down May 2023 | |
| , | Renamed BioDuro, Jan 2025 | |
| Gennova Bio | Pune, India | mRNA vaccine |
| , | Acquired by Cephalon, Aug 2009 | |
| , | Website down, Jan 2024 - Jul 2024 | |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| , | Merged into First Wave Bio | |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| , | ||
| , | Website taken over, Apr 2023 | |
| MabSwitch | San Carlos, CA | Regulatable Antibodies |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| , | Renamed Annoviant | |
| , | Acquired by Transnetyx, Feb 2021 | |
| , | Merged with Zafgen, May 2020, became Larimar Therapeutics | |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| , | Acquired by Gerresheimer, Jul 2019, up to €350M | |
| , | Acquired by Innoviva, Aug 2022, $149M | |
| , | Shut down Jul 2023 | |
| , | Acquired by Leap Therapeutics, Jan 2023 | |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| , | No website Dec 2019 - May 2023, Fannin Innovation Studio company | |
| Biocorp | Issoire, France | Medical Devices |
| Proxygen | Vienna, Austria | Cancer Therapies |
| , | Gone 2013 | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Website down Dec 2017-May 2018 | |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| , | Shut down June 2013 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Acquired by Reliable HealthCare Logistics | |
| , | Website gone, Sep 2018 | |
| , | Liquidated, Nov 2023 | |
| , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active | |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| , | part of SK pharmteco | |
| , | Acquired by Audentes Therapeutics, Sep 2015 | |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| , | Acquired by Vyaire Medical, Apr 2017 | |
| , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 | |
| Stago | Asnières sur Seine, France | Diagnostics |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| , | 10 years in stealth mode | |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| , | Acquired by N-Power Medicine, Jan 2025 | |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| , | Renamed MyriO Tx | |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| , | Now CIT Ortho | |
| , | Nothing out there but a facebook page | |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| , | Bought by Allergan, Oct 2015, $2.1B | |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| , | Restructured. Unknown Status. | |
| , | Renamed Medexus Pharmaceuticals, Dec 2018 | |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Appili Therapeutics | Halifax, NS | Small molecule |
| , | Acquired by Abbott, Jan 2004, $1.2B | |
| , | Renamed Viage Therapeutics | |
| , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker | |
| , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones | |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| , | Renamed Olema Oncology | |
| , | Acquired by Teva, Jul 2008, $7.46B | |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | Acquired by Thermo Fisher, Oct 2021 | |
| , | Now ClinArt MENA | |
| , | Website down Apr 2021 - Sep 2021 | |
| , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities | |
| , | ||
| , | Merged with Capellon, 2001 | |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy |
| , | No website update since 2014, Feb 2023 | |
| , | Renamed Samsara Vision, Nov 2020 | |
| Mersana Therapeutics | Cambridge, MA | Drug Delivery |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| , | Website gone Jan 2024 | |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| , | Renamed Cardea, Jan 2019 | |
| Vetter | Rankweil, Austria | Aseptic Filling |
| , | Seem to have disappeared after development status halted, 2016 | |
| , | Renamed Carisma Therapeutics, 2018 | |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| , | Shut down Nov 2020 | |
| , | Renamed Firefly Neuroscience, Nov 2023 | |
| , | Relaunched as Code Biotherapeutics | |
| , | Liquidated Oct 2002 | |
| , | Shut down Dec 2022 | |
| Delpharm | Huningue, France | Contract Manufacturing |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| , | Bought by Teva, Jun 2014 | |
| , | Acquired by Cambrex, Sep 2016, $25M | |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Immunovant | Durham, NC | Monoclonal Antibody |
| , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker | |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| , | No news from 2012-2020 | |
| , | Merged into Acer Therapeutics, Sep 2017 | |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Staidson Biopharma | San Pablo, CA | Biologics |
| , | Website down Jan 2023 - Jul 2023; fka Cell Point | |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| Latent Labs | London, UK | AI models to design and optimize proteins |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| , | Bought by Actelion, Sep 2013, $250M | |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| , | Website down Sep 2021 - Jan 2022 | |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| , | No website, Mar 2015 - Aug 2021 | |
| , | Possibly rebranding as Bioscience Laboratories, Jan 2019 | |
| ProPharma Group | Washington, DC | Consulting |
| , | Acquired by Medtronic Aug 2010 | |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Novartis, Apr 2018, $8.7B | |
| , | Renamed BeCytes Biotechnologies, Jul 2023 | |
| , | Renamed Synchronicity Pharma, Mar 2019 | |
 |
Brunswick, ME | InSphero | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 | |
| , | ||
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| , | Bought by BMS, Nov 2019, $74B | |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| , | Website down Jul 2021 - Jan 2022 | |
| , | Bankrupt. Assets sold May 2013 | |
| , | Website down Feb 2024 - Jul 2024 | |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| , | Website gone, Sep-Nov 2017 | |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| , | ||
| , | Website down Feb 2021 - May 2021 | |
| , | Dissolved 2003, IP acquired by Integra LifeSciences | |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| , | Acquired by MedGenome, Feb 2016 | |
| , | Renamed Affinia Therapeutics | |
| , | Doesn't seem serious, Feb 2024 | |
| , | Renamed Incyclix Bio | |
| , | Acquired by J&J, May 2018, $140M + $900M milestones | |
| , | Acquired by Islet Sciences Mar 2012 | |
| , | Renamed Berg Pharma 2009 | |
| , | ||
| , | Renamed UNION Therapeutics, Oct 2018 | |
| , | Renamed LuinaBio, 2016 | |
| KiOmed Pharma | Liège, Belgium | Devices and Implants |
| , | Renamed Afyx Therapeutics, Sep 2018 | |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| , | Acquired by GSK, Sep 2019 | |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| , | ||
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| , | ||
| , | Website gone Jul 2018 | |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| , | Acquired by Bio-Techne, Jul 2022 | |
| , | Merged into Bend Bioscience, Sep 2024 | |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 | |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| , | Renamed Intus Bio, Oct 2022 | |
| , | ||
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| , | Website down Aug 2022 - Nov 2022 | |
| , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 | |
| , | Now PharmaForm | |
| , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones | |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Niche Generics | Hitchin, UK | Contract Generics |
| , | Product Acquired by Biogen, May 2017 | |
| , | Website gone May 2018 | |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Almac | Souderton, PA | Pharmaceutical Services |
| , | Renamed CRISM Therapeutics, Jul 2024 | |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| , | ||
| , | Renamed Transcripta Bio, Apr 2024 | |
| , | Website gone, Jan 2020 - Jan 2021 | |
| , | Website gone, Aug 2017 | |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| , | Renamed Sangamo Therapeutics, Jan 2017 | |
| , | Bought by Stryker, Jul 2017 | |
| BaseCure Therapeutics | , | |
| , | Acquired by Invitae, Jun 2019 | |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| , | Bought by Elanco (Lilly) Jan 2012 | |
| , | Acquired by reverse merger, Dec 2023; fka Pergamum | |
| Poseida Therapeutics | San Diego, CA | Genome Editing Technologies |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| , | Bought by Avantor Sciences, Nov 2017, $6.5B | |
| Axplora | Leverkusen, Germany | API manufacturing, kilo lab |
| , | Renamed Humonix Biosciences, Jul 2023 | |
| , | Acquired by Wacker Feb 2021 | |
| , | ||
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| , | Acquired by Genmab, May 2024, $1.8B | |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| , | Now Medivators | |
| , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 | |
| Apollo Endosurgery | Austin, TX | Lab Band |
| , | Acquired by Henogen, Jul 2003 | |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| , | Acquired by Stada, Aug 2007, €125M | |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Clinilabs | Eatontown, NJ | Clinical Research |
| , | ||
| Parexel | Newton, MA | Clinical Research |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| , | Acquired by Genome Therapeutics, Nov 2003 | |
| , | Acquired by BBI Solutions, Jan 2022 | |
| Dandelion Science | Virtual, | AI neuromodulation platform |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| , | Acquired by Centessa | |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| , | Acquired by Valeant, $236M Dec 2014 | |
| , | Acquired by Enochian BioSciences, Apr 2016 | |
| , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged | |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| , | Renamed RoslinCT | |
| , | Website down Oct 2022; Strategic Alts, Mar 2022 | |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| , | Acquired by BioLife Solutions, Sep 2021 | |
| , | ||
| Epygen Biotech | Maharashtra, India | Biosimilars |
| Lead Pharma | Oss, Netherlands | Small Molecules |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 | |
| , | Acquired by Smith & Nephew, Sep 2013, $782M | |
| , | Acquired by Ultragenyx, Jul 2022, $75M | |
| AccuVein | Medford, NY | Vein Visualization |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| , | fka BioPharm Informatics, seems gone Jul 2019 | |
| , | Presumed gone | |
| , | Not actively doing anything Dec 2024, just asking for investments | |
| , | Closed, Dec 2017 | |
| , | ||
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| , | Liquidation 2012 | |
| , | Website down Dec 2023 - May 2024 | |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen | |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| , | Sold Assets, everyone resigned, stock delisted, Dec 2016 | |
| , | Merged with Qiagen | |
| , | Acquired by Attwill Vascular, Nov 2017 | |
| Omnica | Irvine, CA | Contract Medical Device Design & Manufacturing |
| |
Madison, WI | Catalent | Biologics Manufacturing & Cell Line Development |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| , | Acquired by Histogen via Reverse Merger, Jun 2020 | |
| , | Acquired by eGenesis, May 2020 | |
| Integer | Chaska, MN | Medical & Surgical Devices |
| , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 | |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| , | Bought by Merck, Jul 2016, $1.25B | |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| , | Dissolving, Jul 2024 | |
| , | Website down Aug 2020 - Oct 2020 | |
| , | Website down Jun 2024 - Nov 2024 | |
| , | Shut down Jan 2020 | |
| , | Website down Dec 2023 - May 2024; Closely associated with LignaMed | |
| Windtree Therapeutics | Warrington, PA | Peptides |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| , | Website down Mar 2023 - Dec 2023 | |
| Amsino Medical | Pomona, CA | Devices & Contract Manufacturing |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| , | ||
| , | Renamed Angel Medical Systems, Apr 2023 | |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| , | US ops suspended, sold off Dec 2019 | |
| Simbex | Lebanon, NH | Biomechanical devices |
| , | No filings 2018-2021; No website Nov 2019 - May 2021 | |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| BostonGene | Waltham, MA | Biomedical Software |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| Quell Therapeutics | London, UK | Treg cell therapies |
| , | Acquired by Acumed, Mar 2020 | |
| , | Merged with Pharmalex | |
| , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 | |
| Ipca Laboratories | Mumbai, India | APIs |
| , | ||
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| , | Website down Jan 2021 - Apr 2021 | |
| , | Changed name to VetStem Biopharma, Apr 2015 | |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | ||
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| , | Renamed Jupiter Neurosciences, 2021 | |
| , | Part of Cardiox | |
| Xpress Biologics | Milmort, Belgium | Contract Production of Proteins & DNA for Preclinical Activities |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 | |
| , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 | |
| , | Dissolved, Jul 2016 | |
| , | fka Journey Biosciences | |
| , | Acquired by Merck KGaA, Jan 2021 | |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| , | Merged with Bone Therapeutics, Oct 2022 | |
| , | Merged into Datica, Jun 2019 | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Merged with Bioclinica Mar 2014 | |
| , | Renamed Inform Diagnostics, Jan 2018 | |
| , | Almost no info out there. Spinoff of Neptune | |
| , | ||
| , | Renamed Ena Respiratory | |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| , | Acquired by Gilead, Mar 2024, $4.3B | |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 | |
| Avenue Therapeutics | Bay Harbor Islands, FL | IV Tramadol, Small Molecules |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| , | Website down Dec 2021 - Apr 2022 | |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| , | Shut down Jun 2021 | |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Merged into Molecular Templates, Aug 2017 | |
| , | Acquired by NeoSeq | |
| , | Merged into Eiger Bio, Mar 2016 | |
| , | Renamed METiS Therapeutics, Feb 2022 | |
| , | Website gone Oct 2018; Virtual company | |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| , | Website gone Apr 2018 | |
| , | Shut down Oct 2015 | |
| , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones | |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| , | No website, founded 1999 | |
| , | Closed Jul 2016 | |
| , | Appears defunct, likely late 2007 | |
| Vaxess Technologies | Cambridge, MA | Silk Protein Technology for biologic stabilization |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| , | Acquired by Emergent Biosolutions, Oct 2018, $270M | |
| , | Renamed Sagimet Biosciences, Aug 2019 | |
| , | Website Down Feb 2025 | |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| , | Renamed Ohana Biosciences, Feb 2017 | |
| , | Website down Jul 2021 - Dec 2021 | |
| , | Website down Oct 2021 - Mar 2022 | |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| , | Acquired by Zoetis, Jul 2017, $85M | |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Foundation Medicine | Cambridge, MA | Diagnostic Assay |
| , | Bankrupt, Oct 2013 | |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| , | Changed name to Aevi Genetic Medicine, Dec 2016 | |
| , | Acquired by Advanced Accelerator Applications, Jan 2015 | |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| IQVIA | Overland Park, KS | Clinical Research |
| Sonata Therapeutics | Watertown, MA | Small Molecules, Gene Therapy |
| , | Acquired by Saama Technologies, Aug 2019 | |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| Apcer Life Sciences | London, UK | Consultants |
| Raidium | Paris, France | Foundation Model for precision medicine in radiology |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| , | Renamed Centenara Labs, Sep 2024 | |
| , | Became Aviana Apr 2020, post-merger with several companies | |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| , | Chapter 7 Bankruptcy, Oct 2023 | |
| Lucid Diagnostics | New York, NY | Diagnostics |
| , | Renamed RenalGuard | |
| , | Assets acquired by Boca Biolistics, Feb 2015 | |
| , | Shut down Mar 2018 | |
| , | Gone, 2-19-14 | |
| , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 | |
| , | Acquired by Astellas, Apr 2020 | |
| NIOX | Uppsala, Sweden | Asthma management device |
| , | Renamed Morphic Medical, Jul 2023 | |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| Aspen Pharmacare | Port Elizabeth, South Africa | Small Molecules |
| , | Seems gone | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Acquired by Hologic, Nov 2021, $160M | |
| AnHeart Therapeutics | Hangzhou, China | Orally available small molecule |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| , | Acquired by Abbott, Feb 2016 | |
| Holloway America | Springfield, MO | Vessels, Tanks |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| , | Merged with Inverseon to become Invion, Aug 2012 | |
| , | Website down Jun 2024 - Nov 2024 | |
| , | One guy, Feb 2024 | |
| Benchling | San Francisco, CA | Biotech Software |
| , | Exclusively licensed product to Cooper Surgical | |
| Dabur Research Foundation | Ghaziabad , India | Preclinical Contract Research |
| , | Renamed Microbial Machines, May 2022 | |
| Evergreen Therapeutics | Shenzhen, China | AI Pharmaceutical Company |
| , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 | |
| , | Bought by Astellas, Dec 2018 | |
| , | Now EpicentRx | |
| AccelBio | Brooklyn, NY | Cell Analysis Robotics, Cells |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| , | Seems unserious | |
| , | Renamed Stellate Therapeutics, Jun 2020 | |
| Patrin Pharma | Skokie, IL | Generics |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 | |
| , | Shut down Dec 2023 | |
| Allogene Therapeutics | South SF, CA | CAR-T |
| , | Folded into parent, Sep 2023 | |
| , | ||
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| , | ||
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Alkermes | Dublin, Ireland | Small Molecules |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| , | Acquired by Cytek Biosciences, Nov 2021 | |
| Bracco | Monroe Township, NJ | Imaging |
| , | Website gone Jul 2015 | |
| Trilations | Kontich, Belgium | Strategic Consulting |
| , | Website down Jul 2021 - Feb 2022 | |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| , | Website gone May 2020; No news since 2014 | |
| , | Bought by Eli Lilly, Feb 2020, $1.1B | |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| , | Changed name to Corvia Medical Jun 2015 | |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| , | Assets Acquired by Pressure Biosciences, Dec 2017 | |
| PerkinElmer | Waltham, MA | Lab services |
| , | Gone | |
| PharmaLex | Mannheim, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Shut down after trial failure 2018 | |
| , | Folded in to Sequoia Vaccines | |
| , | Acquired by Oncternal via reverse merger ticker, Jun 2019 | |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| PMV Pharma | Princeton, NJ | P53 regulators |
| , | Gone, May 2018 | |
| , | Renamed Iveric Bio, Apr 2019 | |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| , | Acquired by Lupin | |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Elucid | Boston, MA | Arterial Analysis Software |
| , | Parent company is worthless public company, Jan 2025 | |
| , | Acquired by Bio-Techne, 2018 | |
| STgen Bio | Incheon, Korea | Biologics Contract work |
| Niramai | London, UK | AI-breast cancer detection device |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Malvern Analytical | Malvern, UK | Preclinical CRO |
| , | Website gone Dec 2020 - Apr 2021 | |
| , | No website, Dec 2019 - Aug 2021 | |
| , | Gone 2019 | |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| , | Renamed Rainier Therapeutics, Nov 2018 | |
| , | Business filings late Aug 2022 | |
| , | Website gone Sep 2017 | |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| , | Renamed Tesis Biosciences, Nov 2021 | |
| YMC Process Technologies | Devens, MA | Purification Technology |
| , | ||
| , | Website gone Nov 2019 - Dec 2020 | |
| , | Acquired by Allergan, Jul 2015, $560M + milestones | |
| , | Website down Jul 2021 - Dec 2021 | |
| , | ||
| , | Acquired by Azur Pharma 2007 | |
| , | Acquired by Esteve, Jan 2020 | |
| , | ||
| CureGene | Shanghai, China | |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| , | Acquired by Quidel, Dec 2021, $6B | |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| , | Gone Jan 2016 | |
| , | New Company, no website as of Apr 2014, still none in Dec 2019 | |
| , | Acquired By ArthroCare, Nov 2004, $130M | |
| , | Acquired by Eliem Therapeutics, Jun 2024 | |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| , | Renamed Regencor | |
| , | Shut down May 2020 | |
| , | Subsumed into parent | |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 | |
| , | Website Gone, Aug 2016; SBIR grant | |
| , | Closed 2013 | |
| DefiniGEN | Cambridge, UK | Human Cell Models of Rare Diseases |
| , | Acquired by Elanco, Feb 2014 | |
| , | Acquired by Neurocrine, Nov 2022, £48M | |
| , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 | |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| , | Now Enzo Life Sciences | |
| MiNA Therapeutics | London, UK | Small activating RNA |
| , | Website down Oct 2021 - Jul 2022 | |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| , | Bought by Jazz Pharmaceuticals, May 2021 | |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| , | Bought by LabCorp 2009 | |
| , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo | |
| Saniona | Glostrup, Denmark | Small Molecules |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| , | No website Nov 2019 - Nov 2023 | |
| , | Acquired by Premier Research, May 2021 | |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| , | Renamed United Animal Health, Jan 2018 | |
| , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones | |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| Parexel | Uxbridge, UK | Clinical Research |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| , | Website Gone 8-30-13 | |
| Eurofins CDMO | Fontenilles, France | Eurofins CDMO focuses on APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| , | Renamed SeaGen, Oct 2020 | |
| Becton Dickinson | San Jose, CA | Lots of Biotechnology Products |
| , | ||
| , | Delinquent in CO, 2012 | |
| IONETIX | Lansing, MI | Radiopharmaceutical |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Lifotronic Technology | Shenzhen, China | IVD, Reespiratory Devices, Wound Care, Pain Management |
| , | Renamed Protara Therapeutics, May 2020 | |
| Tokyo, | ||
| , | Website down Dec 2021 - Jul 2022 | |
| , | ||
| Oncocross | Seoul, Korea | AI Drug Discovery |
| , | Bought by Roche, Aug 2014 | |
| BioNova Pharm | Shanghai, China | Biologic |
| , | Acquired by PharmaLex, Apr 2014 | |
| Crown Bioscience | Taicang, China | Drug Development |
| , | Renamed Shorla Oncology, Mar 2022 | |
| , | Acquired by Natus, Dec 2022 | |
| Leap Therapeutics | Cambridge, MA | Monoclonal antibody |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| , | Cant find any confirmation they are active | |
| , | No site | |
| 3B BlackBio | Bhopal, India | PCR products |
| , | Website Gone Mar 2018 | |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| , | ||
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| , | Acquired by Sanofi, Sep 2020 | |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| , | No info, Aug 2022 | |
| , | Consultancy with website copyright 2009 as of 2020 | |
| , | Renamed Corza Medical after acquisition/merger | |
| , | Acquired by Eli Lilly, Aug 2024, $3.2B | |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| , | Renamed Northway BiotechPharma | |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate | |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| Thelper | Oslo, Norway | Antiviral Antibody Drug Conjugates |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| PHAXIAM Therapeutics | Lyon, France | Loading Red-Blood Cells with Therapeutics |
| Benchmark Research | Sacramento, CA | Clinical Research |
| ImmunoPrecise Antibodies | Victoria, BC | Custom Antibodies |
| , | Shut down Oct 2021 | |
| , | Bought by BioMarin, closed | |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| , | Acquired by Baxter, Mar 2010, $330M | |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Novotech | Bangalore, India | Clinical Research |
| FIZE Medical | Tel Aviv, Israel | Real Time Urine Output Data |
| , | Preclinical for 5+ years, not a registered business in CA | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Shut down May 2024 | |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Qardio | Covina, CA | Portable Heart Monitors |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Silk Road Medical | Plymouth, MN | Carotid artery diseases treatments |
| Bonovo Orthopedics | Beijing, China | Spinal Surgery Solutions |
| , | ||
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| , | Renamed InnoN, Apr 2020 | |
| , | Pretty sure this is just Morphic Therapeutics | |
| , | Website gone Oct 2017 | |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| , | Website gone Sep 2021, execs gone | |
| , | Acquired by NeoTX, May 2022 | |
| RaySearch Laboratories | Heverlee, Belgium | Cancer Research Software |
| , | Merged with Pacific Biomarkers, Nov 2018 | |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| , | Bought by Radiant Research, Nov 2012 | |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
 |
Leverkusen, Germany | WuXi Biologics | Biologics & vaccines development & formulation and fill drug product manufacturing. |
| , | Acquired by Steris, Jul 2012 | |
| , | Gone | |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| , | Renamed Microchips Biotech, 2014? | |
| , | ||
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| , | Now bluebird bio | |
| SonoThera | South SF, CA | Ultrasound-Guided Gene Therapy |
| , | Merged with R&Q, 2020, renamed RQM+ | |
| , | Acquired by Full Life Technologies, Nov 2022, up to $245M | |
| , | Website down Jul 2024 - Dec 2024 | |
| , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 | |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| , | Shut down, May 2010 | |
| ABL | Lyon, France | Viral Vector CDMO |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| , | Website down Jul 2022 - Oct 2022 | |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Medtronic | Danvers, MA | Medical Devices |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| , | Website down Dec 2019 - Mar 2020 | |
| , | Website Down May 2024 - Nov 2024 | |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| , | Owned by Abbot Vascular | |
| tiakis Biotech | Kiel, Germany | Biologics |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| , | ||
| , | Acquired by Boston Scientific, Aug 2019, $4.3B | |
| Imeka | Sherbrooke, QC | Neuroimaging |
| , | Acquired by Pfizer, Dec 2021, $6.7B | |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| , | Gone | |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| , | Acquired by Merck KgAA/MSD Jun 2020 | |
| , | Acquired by ERT, Sep 2017 | |
| , | Shut Down 2009 | |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| , | Bought by Allergan | |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| , | Website down Oct 2022 - Apr 2023 | |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| , | Rebranded as Light Chain Bioscience, Jul 2019 | |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| , | Bought by Philips, Jun 2017 | |
| , | Stopped working on drugs Feb 1999 | |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| , | Renamed QurCan Therapeutics | |
| GenEditBio | Hong Kong, China | Gene Editing |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| , | Bought by Merck, $400M, 2006 | |
| , | Renamed HCS Pharma | |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| , | Part of IntegrityBio | |
| Valneva | Livingston, UK | Biologics Manufacturing |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| , | Renamed Arch Oncology | |
| , | Website gone Apr 2020 - Aug 2021, no info | |
| , | Virtual company that may not longer be active | |
| |
Bad Aibling, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Acquired by PerkinElmer, May 2021, $260M | |
| Roche | Buonas, Switzerland | Diagnostics |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| , | Ceased operations Dec 2012 | |
| , | Renamed Zeo Scientific, Mar 2024 | |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| , | Assets acquired by BioStem Technologies, Mar 2023 | |
| , | Changed name to Innocutis 2011 | |
| , | Website gone, Jan 2019 | |
| , | Acquired by Digilab | |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| , | Assets bought by DiscernDx, Feb 2018, $1.85M | |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| OFD Biopharma | Albany, OR | Lyophilization |
| , | One guy, nothing going on, established 1991 | |
| , | Renamed Sensei Biotherapeutics, May 2018 | |
| , | Website Gone Jun 2021 - Oct 2021 | |
| , | Acquired by Protagen Protein Services, Apr 2019 | |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| , | Website gone Dec 2023 - Jul 2024 | |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| CellChorus | South SF, CA | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| , | Website down Jul 2024 - Dec 2024 | |
| , | Acquired by Pharmacosmos, Nov 2021, $225M | |
| , | Filings late Sep 2022 - Oct 2023, single person | |
| , | Acquired by St. Jude Medical, Oct 2010, $1.3B | |
| , | Shut down Nov 2023 | |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| , | Closed 2013 | |
| , | Acquired by Bionano Genomics, Nov 2022 | |
| , | Bankrupt 2011 | |
| , | Renamed Neuspera Medical, Aug 2015 | |
| Ergomed | Zagreb, Croatia | Clinical Research |
| ESSA Pharma | Houston, TX | Small molecules for cancer |
| , | Renamed Viacyte | |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| , | Acquired by Illumina, Jan 2016 | |
| Abbott | Menlo Park, CA | Drug-Eluting Stents |
| , | ||
| , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 | |
| , | Acquired by Beckman-Coulter, Nov 2020 | |
| Genprex | Austin, TX | Immunogene Therapy |
| , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 | |
| , | Acquired by SK Biopharmaceuticals, Aug 2023 | |
| , | Website down Apr 2021 - Sep 2021 | |
| , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M | |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares | |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| , | Company renamed Oncosil Medical | |
| , | Acquired by Pfizer, Nov 2021, $2.3B | |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Emmes | Rockville, MD | Clinical Research Organization |
| , | Website down Aug 2024 - Feb 2025 | |
| , | Website taken over Feb 2022 - Apr 2022 | |
| Mabqi | Grabels, France | Antibody Discovery |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| , | All employees have moved on. Website not changed since 2007. | |
| , | Merged into Stallergenes to become Stallergenes Greer | |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| , | Website down Dec 2023 - Jul 2024 | |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| , | ||
| , | ||
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| , | Shut down Dec 2013 | |
| , | No update since 2012 as of 2020 | |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| , | ||
| Leaf Expression Systems | Norwich, UK | Plant-based Expression of Proteins |
| , | Bankrupt, Aug 2017, assets bought by Enesi Pharma | |
| , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M | |
| Sania Therapeutics | London, UK | CNS Treatments |
| , | Acquired by Advanced Instruments, Aug 2021 | |
| , | Merged with Aravive Biologics, Oct 2018 | |
| , | Merged with SmartBead Technologies to become Pronostics | |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| , | No news 2017-2024, business filings late Jun 2022 | |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| , | Website gone May 2019 - Dec 2020 | |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| , | Does not seem active Oct 2019 | |
| , | Shut down Feb 2023 | |
| , | ||
| , | Bought by Intrexon, 2011 | |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| , | Failed 2018, shell | |
| , | Changed name to Auven Therapeutics, Mar 2013 | |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| , | Business no longer active in MD, Nov 2022 | |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| , | Acquired by Medtronic, Oct 2020 | |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| , | Acquired by Meridian Bioscience, Apr 2022 | |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| , | Acquired by Biosense Websiter, Sep 2021 | |
| , | Merged with BioSTAR West and became Synedgen 2009 | |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | Winding down Jan 2024 | |
| , | Acquired by Capsugel, Jan 2016 | |
| , | Acquired by 3D Systems, Oct 2021 | |
| , | Website being updating from 2016-2018 | |
| , | Assets acquired by Aurinia, Aug 2021, $7M | |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| , | Renamed NuChem Sciences, Apr 2021 | |
| Pharmaron | Northamptonshire, UK | R&D Services |
| , | Dissolved, Jan 2016 | |
| , | Acquired by Perkin-Elmer, 1998 | |
| Valink Therapeutics | Boston, MA | Bispecific Antibodies |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| QuantaBio | Beverly, MA | PCR equipment |
| Boston Scientific | Spencer, IN | Medical Devices |
| , | Renamed ALX Oncology, Jun 2018 | |
| , | ||
| Luzsana | Lianyungang, China | Various Drug Products |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Catalyst Clinical Research | Clinton, CT | Clinical research solutions to the global biopharmaceutical industry |
| , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 | |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Vascular Technology | Nashua, NH | Surgical Devices |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Eurofins CDMO | Ghent, Belgium | Eurofins CDMO focuses on APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| , | Acquired by 3D Systems, May 2021 | |
| NovaBay Pharmaceuticals | Emeryville, CA | Diagnostics |
| , | Acquired by SuperGen, Apr 2006, $18M | |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| , | Website down Oct 2021 - Jul 2022 | |
| Rezolute | Bend, OR | Biologics |
| |
Schlieren, Switzerland | InSphero | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| , | Website from 2011, drug was in phase 1 for at least six years if still active | |
| , | Website gone Jun 2020 | |
| , | Website gone, 11-30-14 | |
| , | Bought by Consort Medical for $374M, Sep 2014 | |
| , | Renamed Clasp Therapeutics, Mar 2024 | |
| , | ||
| , | Acquired by Maverix Medical, Mar 2024 | |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Wasdell Group | Northamptonshire, UK | Contract Manufacturing - nonsterile |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Gone | |
| , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary | |
| , | Gone 2019 | |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| , | No website Jun 2019, 2014 startup | |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| , | Bankrupt, Selling Assets Jul 2023 | |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sunho Biologics | Nanjing, China | Biologics |
| Roxall | Oststeinbek, Germany | Diagnostics, Allergy treatments |
| Biopticon | Princeton, NJ | Tumor Imaging |
| , | Gone Apr 2020, facility bought by Akron Biotech | |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| Bifrost Biosystems | Cambridge, MA | Optical Pooled Screening Technology |
| , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals | |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Repare Therapeutics | Cambridge, MA | Synthetic Lethal Therapeutics |
| , | Website gone Jun 2022, not registered in MA | |
| , | Acquired by Kiromic, Jul 2021 | |
| , | Changed name to Galectin Therapeutics | |
| Analogic | Peabody, MA | Medical Imaging |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address | |
| , | Bought by Genzyme | |
| , | Main Assets acquired by Qiagen, Mar 2015 | |
| , | Renamed Bolder Surgical | |
| Perceptive | Nottingham, UK | Medical Imaging |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| , | Seems gone, Aug 2022; No filings after 2019 | |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| , | Gone | |
| , | Acquired by Avenue Therapeutics, Nov 2022 | |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| , | Acquired by Forest Labs Dec 2006 | |
| LeMaitre Vascular | Kensington, Australia | Vascular surgical devices |
| , | Acquired by Thermo Fisher, Mar 2021, $550M | |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Pfizer | Vega Baja, PR | Small Molecules, Biologics, Vaccines |
| Automata | London, UK | Lab workflow automation platform |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| , | Renamed Ceretype Neuromedicine, Feb 2020 | |
| , | Renamed Redona Therapeutics, Jan 2023 | |
| , | Shut down Apr 2019 | |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| , | Renamed Tioga Cardiovascular | |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 | |
| Aera Therapeutics | Cambridge, MA | Genetic Medicines |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| , | Acquired by Stryker, Feb 2018, $216M | |
| , | Merged with ProCept Inc, Dec 1998 | |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| Rhythmedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| STAb Therapeutics | Madrid, Spain | T cell redirecting |
| , | Website down Jan 2024 - Aug 2024 | |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| , | Website down Aug 2022 - Feb 2023 | |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| Novozymes | Franklinton, NC | Enzymes, Biologic Reagents |
| Interplex Medical | Milford, OH | Contract Device Engineering & Manufacturing |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| , | Closed 2011 per Mark Kaufmann, former CEO | |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| , | Acquired by Illumina, Jan 2013, $350M+ | |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Suspended trading due to scandal | |
| , | Renamed LadRx Sep 2022 | |
| Molsoft | San Diego, CA | Drug Design Software |
| , | ||
| , | Acquired by MannKind, Dec 2020 | |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| , | Website gone May 2018 | |
| , | Website Gone Jan 2019 | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | ||
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 | |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| , | Acquired by Sanofi Oct 2009 | |
| , | Acquired by AskBio, Apr 2020 | |
| Olema Oncology | San Francisco, CA | CAR T brake |
| , | Renamed Verana Health, Jul 2018 | |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Evozyne | Chicago, IL | Protein Design Platform |
| , | Acquired by AstraZeneca, Feb 2023 | |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Delta4 AI | Schindellegi, Switzerland | AI Drug Discovery |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Catalyst Clinical Research | Wilmington , NC | Clinical research solutions to the global biopharmaceutical industry |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| , | Website gone Oct 2022; One co-Founder moved on Feb 2020 | |
 |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| , | Merged with Greer Labs to become Stallergenes Greer | |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones | |
| Delveinsight Business Research Group | New Delhi, India | Business Consulting |
| , | Acquired by Curative, May 2020 | |
| , | Closed down according to investors | |
| , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics | |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| , | Bought by Opko, $60M stock, Jul 2016 | |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| , | Merged with PulmoSonix to become iSonea, 2011 | |
| , | Shut down Dec 2013 | |
| , | Hijacked website Feb 2022 | |
| Brii Biosciences | Beijing, China | Bringing medicines to Chinese market |
| Xybion | Chennai, India | Cloud LIMS, Quality |
| Orochem | Naperville, IL | Reagents, Automation |
| , | Renamed Regentys, Nov 2017 | |
| , | ||
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| , | No business filings in CA, Nov 2016 - Jul 2024 | |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| , | Renamed Cell Theranostics, Jan 2022 | |
| Coherus BioSciences | Redwood City, CA | Biologics, Biosimilars |
| , | Sold drugs to Alcon, 2010 | |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| , | ||
| , | Renamed Intellirod Spine | |
| , | Website down Mar 2022 - Sep 2022 | |
| , | Acquired by Ligand Pharmaceuticals 2009 | |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| , | Shut Down 2012 | |
| Persephone Biosciences | San Diego, CA | Analysis of Poop to Discover Cancer Treatments |
| , | Acquired by Roche, Apr 2008, $160M + $15M milestones | |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public | |
| , | Acquired by AstraZeneca, Aug 2022 | |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| , | Chapter 11 Bankruptcy, Feb 2024, winding down | |
| , | Acquired by Zymergen, May 2021 | |
| Novosanis | Wijnegem, Belgium | Diagnostics, Drug Delivery |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| , | Renamed Vista.ai | |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Ergomed | Krakow, Poland | Clinical Research |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| , | Business dissolved 2014 | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Appear inactive, 2019; fka Target Pharmaceuticals | |
| , | No website Jun 2021 - May 2023; been around since 2007 | |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| , | Acquired by Baxter 2011 | |
| , | ||
| , | Folded | |
| , | Website down Dec 2022 - Apr 2023 | |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| Ribomic | Tokyo , Japan | Aptamers |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| , | Rebranded at Sebra | |
| , | Website down Aug 2023 - Apr 2024 | |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Bridge Informatics | Salem, MA | Genomic Data Services |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Third Harmonic Bio | Cambridge, MA | Allergy & Inflammation Treatments |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| TG Therapeutics | Morrisville, NC | Biologics |
| |
Sisseln, Switzerland | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Shut down Jan 2022 | |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| , | Not a registered business in WA, no updates 2015-2022 | |
| , | Not Active | |
| , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment | |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 | |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| , | Website gone, company going inactive | |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| CMP Pharma | Farmville, NC | Small Molecules |
| , | Renamed Hutchmed, Mar 2021 | |
| , | Shut down 2014 | |
| Evogene | Rehovot, Israel | Computational Biology |
| , | Website gone Nov 2019 | |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| , | Renamed Encoded Therapeutics, 2019? | |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Rezo Therapeutics | San Francisco, CA | |
| , | Acquired by Ethicon, Aug 2008 | |
| , | website ©2007, last news 2013 | |
| , | Gone | |
| , | Acquired by Actavis, Nov 2014, $675M | |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Amarin | Dublin, Ireland | Small Molecules |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| , | No activity since 2012, not registered in MA as a business | |
| , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics | |
| Suono Bio | Foxborough, MA | Ultra-rapid delivery of novel therapeutics |
| , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo | |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Aixa Bio | Cambridge, MA | AI genomics |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| CNS Healthcare | Memphis, TN | CNS Clinical Research |
| , | Shut down late 2021 | |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| LinkChem | Shanghai, China | CDMO |
| , | Gone post-2011 | |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| , | Acquired by Life Technologies Jan 2010 | |
| , | Website Down May 2024 - Nov 2024 | |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| , | Acquired by Sanofi, Apr 2021, $1.45B | |
| , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics | |
| , | ||
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| , | CEO Founder gone late 2021 | |
| , | Acquired by Novasite Pharmaceuticals, Jun 2005 | |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| , | part of Sumitomo; aka SDP Oncology | |
| , | Gone post 2001 | |
| , | Website down May 2021 - Sep 2021 | |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| , | Acquired by Recipharm, Feb 2022 | |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Acquired by AMAG Pharmaceuticals, Jan 2019 | |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| , | Renamed Ichnos Glenmark Innovation, Jan 2024 | |
| , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 | |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| , | Website down Feb 2021 - Jul 2021 | |
| , | Acquired by NuVasive, Feb 2021, $150M | |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| , | Acquired by Thermo Fisher, Jan 2021 | |
| , | Acquired by Haemonetics, Jan 2021, $510M | |
| , | Shell company, went out of real business in 2012 | |
| , | Renamed OmeCare | |
| , | ||
| , | Now known as Co-Diagnostics | |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| , | Acquired by Biohaven, Jan 2021 | |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| , | Website down Aug 2022 - Jan 2023 | |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| , | Merged into Biscayne Pharmaceuticals, Oct 2015 | |
| , | Reverted to Biogen, Mar 2015 | |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| , | ||
| , | Acquired by EyeGate Pharmaceuticals, Oct 2021 | |
| , | Acquired by JanOne, Sep 2022 | |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| , | Acquired by Blade Therapeutics, Sep 2019 | |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| , | Comically outdated website, Nov 2019, no employees on LinkedIn | |
| , | Rolled into BridgeBio, Feb 2024 | |
| , | Bought by Novartis, Dec 2018, $2.1B | |
| , | Gone | |
| , | Changed name to Epoch Pharmaceuticals, 1995 | |
| Pathos | Chicago, IL | In-Licensing Clinical Drugs |
| , | Gone 2007 | |
| , | Believe they were folded back into Atara or shut down entirely | |
| , | Acquired by Allergan, Aug 2016, $95M | |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 | |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Website taken over Feb 2024 | |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| , | Website down Dec 2021 - Apr 2022 | |
| Presbia | Dublin, Ireland | Microlenses |
| BGI | Hong Kong, China | Genetic Testing |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| , | No longer active in CA as of 2014 | |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| , | Now Valeant | |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| , | Bought by Shire, $32B, Jun 2016 | |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Amplion | Bend, OR | Pharma Intelligence Platform powered by Machine Learning and Biomedical PhDs |
| , | Acquired by Roche, Feb 2018; $1.2B | |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Delpor | Brisbane, CA | Drug Delivery System |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| , | Website Gone | |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| , | Website down Feb 2022 - Jul 2022 | |
| , | Acquired by Colby Pharmaceuticals 2012 | |
| , | No news 2016 - Oct 2024 | |
| , | Renamed Admedus, Nov 2013 | |
| , | Gone 2018 | |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Kerecis | Arlington, VA | Wound Healing |
| , | Renamed Carterra, May 2017 | |
| , | Shut down, Sep 2004 | |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| , | Renamed CereHealth | |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| , | Website Gone, Sep 2020 | |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM | |
| , | No news 2015-2021 | |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| , | Renamed ClearLight Biotechnologies, Oct 2018 | |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| , | ||
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| , | Sold Assets, Shut down operations, may exist as a shell | |
| , | Website down Jun 2024 - Dec 2024 | |
| , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 | |
| Cellink | Kyoto, Japan | Bioprinting |
| , | Acquired by Ergomed, Dec 2020, $18M | |
| , | Acquired by Abbott, Jan 2019 | |
| , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences | |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| , | Now Cornerstone Therapeutics | |
| , | Assets acquired by Progenity, Sep 2019 | |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Ximedica | San Francisco, CA | Medical Device Services |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| , | ||
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| , | Part of Molecular Pathology Laboratory | |
| |
Suzhou, China | WuXi Biologics | Biologics & vaccines CDMO for antibodies and other proteins from mammalian expression systems. |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics | |
| , | Acquired by Cepheid, Dec 2021 | |
| , | Renamed Flash Biosolutions, Oct 2024 | |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| , | CEO gone, delinquent business filings May 2022 | |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| , | Bought by Smith & Nephew | |
| GLR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Avantor Sciences | Radnor, PA | Lab Products & Chemicals |
| , | ||
| Glenmark | Mumbai, India | Generic Small Molecules |
| Olfa Thera | , | |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| , | Renamed SciY | |
| , | Acquired by Zymergen, Mar 2020 | |
| Baxter | Cali, Colombia | Medication Delivery |
| , | Seems gone Jan 2024 | |
| , | Changed name to THERAmetrics, Jun 2013 | |
| , | Shell acquired by an energy company, Jan 2023 | |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| , | Bought by Shire 2012 | |
| , | Website disappeared, Jan 2016 no info | |
| , | Merged with Adaptimmune, Jun 2023 | |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| , | Renamed miRNA Scientific | |
| , | Renamed Neuropathix, May 2021 | |
| Satya | Hyderabad, India | Small Molecule |
| , | Acquired by Varian Medical Systems, Sep 2011, $10M | |
| scPharmaceuticals | Burlington, MA | Micropump & delivery system |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| , | Acquired by Ixaka, Jan 2021, $54M | |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| Issar Pharmaceuticals | Hyderabad, India | Small Molecules |
| Centrexion Therapeutics | Boston, MA | Pain therapies |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| , | Renamed GeneCentric Therapeutics, 2018? | |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica | |
| , | Gone | |
| , | ||
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| , | Seems gone, reincarnated as Calviri | |
| , | ||
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Website down Apr 2024 - Aug 2024 | |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| , | Bankrupt, Apr 2010 | |
| , | Bought by AtriCure, Aug 2019, $300M | |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| Teleflex Medical | Chalandri, Greece | Surgical and Medical Devices |
| , | Bought by Aldeyra Therapeutics, Jan 2019, $10M | |
| , | Website gone Jan 2019 | |
| , | Merged with RoslinCT, Aug 2022 | |
| Evestra Onkologia | Nowy Dwór Mazowiecki, Poland | Oncology and endometriosis treatments |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| , | Renamed Horizon Therapeutics | |
| , | Renamed Syntrix Pharmaceuticals | |
| , | Website down Mar 2020 - Aug 2020 | |
| , | Shut down Nov 2019 | |
| , | Bought by Sandoz, Jul 1995, #295M | |
| , | Acquired by CMIC, Oct 2023 | |
| , | Seems gone 2019 | |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| , | Dissolved Jun 2017 | |
| , | Closed Oct 2017 | |
| , | Shut down 2012 or later | |
| , | Website down Jan 2021 - Apr 2021 | |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | ||
| , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro | |
| Starling Surgical | Dublin, Ireland | Wound Closure |
| , | Signum Biosciences spinout, now redirected to parent page | |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| , | Dissolved Dec 2018 | |
| PeptiGrowth | Tokyo, Japan | Growth Factor Alternative Peptide |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| , | Website down Jun 2024 - Nov 2024 | |
| , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 | |
| , | No website, Aug 2018. Location houses many biotechs | |
| , | Bought by Roche, May 1997, $11B | |
| , | Changed name to Dendreon | |
| , | Website taken over May 2020 | |
| , | Acquired by Novo Nordisk, Aug 2020, $725M | |
| , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos | |
| , | Folded Apr 2017 | |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| , | Acquired by LabCorp, Feb 2015, $5.7B | |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| , | Bought by Biogen Idec 2012 | |
| , | Bought by Juno Therapeutics, May 2015, €52.5 million | |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| , | Acquired by Opko Health , Oct 2009 | |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| , | Part of Pfizer that became part of Viatris | |
| , | Bought by Agilent | |
| , | ||
| Pace Analytical | Greensburg, PA | Analytical Testing |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn | |
| , | Acquired by SeraCare, Aug 2013, Stock | |
| , | Gone Dec 2019 | |
| , | Acquired by Velocity Clinical, Sep 2022 | |
| , | Shut down before Jun 2014 | |
| , | Dissolved Dec 2003 | |
| Delpharm | Evreux, France | Contract Manufacturing |
| , | Merged with Chiralgen to form WaVe Life Sciences | |
| , | Renamed NeoTX | |
| , | Acquired by Alere, Feb 2005, $9M | |
| , | Bought by Thermo Fisher, Dec 2010, $2.1B | |
| , | Renamed IN8bio, Aug 2020 | |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| , | Acquired by Illumina, Jan 2011 | |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| F-star Therapeutics | Cambridge, UK | Antibody Engineering |
| , | Website hijacked Apr 2023 - Jun 2023 | |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| TRIFARMA | Chennai, India | APIs |
| , | Changed name to Nfocus Neuromedical | |
| , | Changed name to Integer, Jul 2016 | |
| , | Shut down Apr 2022 | |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| , | Website down Feb 2024 - Jul 2024 | |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 | |
| Brainomix | Ofxord, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| Wasdell Group | Mullagharlin, Ireland | Contract Manufacturing - nonsterile |
| , | Seems closed, Oct 2021 | |
| , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC | |
| , | Acquired by Alere, Feb 2013 | |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| , | Acquired by Synexus, Mar 2016 | |
| Sanofi | Frankfurt, Germany | Small Molecules |
| , | not registered in WA, Feb 2025; No news 2022- Feb 2025 | |
| , | Website gone, Apr 2018, company dissolved Apr 2019 | |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Vir Biotechnology | Portland, OR | Infectious disease therapies |
| , | Acquired by Novartis, Feb 2014 | |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| Horiba Instruments | Irvine, CA | Equipment |
| , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 | |
| Hunter Biodiscovery | Boston, MA | AI Drug Discovery Platform |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| , | Shut down late 2018 | |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| , | Rebranded Avadel Pharmaceuticals Jan 2017 | |
| , | Acquired by Johnson & Johnson, Jun 2012, $19.7B | |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Fonar | Melville, NY | Upright MRI |
| , | Changed name to Prolexys Pharmaceuticals | |
| , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 | |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| , | Bought by MedImmune Oct 2013, $225M | |
| , | Website Down May 2024 - Nov 2024 | |
| , | Bought by Renewable Energy Group, Jan 2014 | |
| , | ||
| , | Bought by Amgen Jan 2012, $1.2B | |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| , | Renamed DxCover, Jun 2021 | |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| , | Website down Jul 2024 - Dec 2024 | |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| , | Acquired by Cedarburg | |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| , | Website down Oct 2020 - Feb 2021 | |
| , | Gone 2019? | |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| , | Merged with Astarte Biologics, Aug 2018 | |
| Genomics PLC | Oxford, UK | Genomic algorithms |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Nanomix | Emeryville, CA | Automated POC diagnostic system |
| , | Now Aptiv | |
| numares | Houston, TX | Clinical Diagnostics |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| , | Website gone, no business filings since 2017 as of Oct 2020 | |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| , | Distributor | |
| , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 | |
| , | Changed name to New York Global Innovations | |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics | |
| , | Shut down 2012 | |
| , | ||
| , | Website down Feb 2023 - Jul 2023 | |
| Innocoll | Princeton, NJ | Surgical / Tissue Implants |
| Salvat | Madrid, Spain | Small Molecules |
| , | Acquired by Agilent, Apr 2007, $246M | |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| , | Dissolved Nov 2005 | |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| NS Pharma | Paramus, NJ | Small Molecule |
| , | Liquidating, Jan 2021 | |
| Aixial Group | Raleigh, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| , | ||
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| , | Acquired by Stryker, May 2023 | |
| , | Bought by Auris Surgical, Apr 2016, $40M | |
| , | Closed Oct 2016 | |
| , | Shut Down 2019 | |
| Cellanome | Foster City, CA | Multiomics Platform |
| , | Website down Jan 2024 - Sep 2024 | |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| , | Acquired by Recipharm, Apr 2020 | |
| , | Ancient Website, not registered in CA Jun 2019 | |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| , | No news 2017 - Jul 2024 | |
| , | Acquired by Baudax Bio, Jun 2023 | |
| , | Website hacked, employees who are gone still appear on Website, May 2016 | |
| , | Website down Oct 2024 - Nov 2024 | |
| Stryker | Mahwah, NJ | Medical Devices |
| , | Website down Oct 2020 - Jan 2021 | |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| , | Sole asset failed early 2017 | |
| , | Renamed Thrive Informatix, Jan 2024 | |
| , | Renamed AcuamarkDx | |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| , | ||
| , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name | |
| , | Acquired by CONMED, 1983 | |
| , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M | |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Moximed | Fremont, CA | Joint treatment |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Renamed Luc therapeutics, renamed Cadent, 2017 | |
| Allez Health | San Diego, CA | Biosensors |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| , | Acquired by Odan Laboratories, Dec 2020 | |
| , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics | |
| , | ||
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| , | Renamed AskBio | |
| , | Gone | |
| , | No info or website, May 2021 - Aug 2021 | |
| , | Acquired by Gilead, Dec 2017, up to $567M | |
| , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 | |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| , | Website down Jul 2023 - Dec 2023 | |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Renamed Hera BioLabs, 2020 | |
| , | Acquired by Ott Scientific, May 2021 | |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| , | Bankrupt, Dec 2023 | |
| , | Website down, not active CA business Jan 2019 | |
| Seraph Biosciences | Detriot, MI | POC Pathogen Detection |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| , | ||
| , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B | |
| , | ||
| , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 | |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| , | Website now a penny stock shill | |
| , | Acquired by BD, Jul 2021 | |
| , | Website crazy outdated, Aug 2024 | |
| , | Merged with CoCrystal Pharma, Nov 2014 | |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| , | Renamed ONWARD | |
| , | Website Down Jan 2022 - Jul 2022 | |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Exscientia | Oxford, UK | Automated Drug Design |
| , | Owned by Coherus Biosciences | |
| , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma | |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| GTP Bioways | Toulouse, France | Contract Biologics Manufacturing, Services |
| , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer | |
| , | Changed name to Oncothyreon, Dec 2007 | |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| MicroPort | Arlington, TN | Medical Devices |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| , | Now Champions Oncology | |
| , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics | |
| , | Presumed gone, academics' side project, emails bouncing | |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière | |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| , | Acquired by Adare Pharmaceuticals, May 2020 | |
| DDi | London, UK | Clinical Software |
| , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B | |
| , | Bought by Videra | |
| MediLink Therapeutics | Suzhou, China | ADC |
| , | Terminated trial, gone 2015 | |
| , | Acquired by Lodo Therapeutics, Sep 2020 | |
| , | Bought from Aptuit by AMRI, Jan 2015 | |
| Creyon Bio | Carlsbad, CA | Oligonucleotide-based Medicines |
| ModeX Therapeutics | Weston, MA | Biologics |
| , | Dissolved 2012 | |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Changed name to Cotinga Pharmaceuticals, Jan 2018 | |
| , | ||
| , | ||
| , | Merged with Medos, 2013 became Xenios | |
| , | Now part of Janssen Pharmaceuticals; fka Centocor | |
| Flownamics | Madison, WI | Automated Sampling |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| , | Gone Jun 2012 | |
| , | Now LBIdx | |
| , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones | |
| , | No news 2017 - 2024 | |
| , | Shut down Aug 2021; fka Neurophage Pharmaceuticals | |
| , | Closed 2013 | |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| CML Biotech | Ernakulam Dist., Kerala | Lab Consumables |
| , | Acquired by Olympus, May 2021 | |
| , | Shut Down 2013 | |
| , | Bought by Gfk, Mar 2012 | |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| , | Acquired by GSK, Sep 2005, $1.7B | |
| Novoste | Norcross, GA | Vascular Brachytherapy |
| , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 | |
| Menarini | L'Aquila, Italy | Small Molecules |
| , | Bought by CareDx, Apri 2016 | |
| , | ||
| , | Website down Aug 2023 - Feb 2024 | |
| , | Renamed Revance Therapeutics | |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| , | Liquidated Jan 2020 | |
| , | Website outdated, doesn't seem serious | |
| , | Renamed Plus Therapeutics, Jul 2019 | |
| Delphinus Medical Technologies | Novi, MI | Breast ultrasound |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Agilent | Cedar Creek, TX | High-Throughput Screening Equipment, Imaging instruments |
| , | Bought by SOTIO, Aug 2018 | |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| , | Business lapsed in CA 2022, boutique at old location, no employees on LI | |
| InnoMedica | Bern, Switzerland | Liposomal drug transport systems |
| Genialis | Boston, MA | Bioinformatics |
| , | ||
| , | Acquired by Hansen Medical, Nov 2007, $4.5M | |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Renamed Solid Therapeutics | |
| , | Merged with Sana Biotechnology, early 2019 | |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn | |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| , | Acquired by Shire, Jan 2015, $5.2B | |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| , | Dissolved May 2015 | |
| , | CEO has numerous other more important jobs, Feb 2025 | |
| Pfizer | Clondalkin, Ireland | Biologics |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| , | Renamed Gyre Therapeutics | |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| , | Acquired by Engrail Therapeutics, Feb 2021 | |
| , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout | |
| , | ||
| , | ||
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Sanofi | Paris, France | Small Molecules |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Hologic | Newark, DE | Diagnostic, Imaging |
| , | Effectively changed name to Tarix Orphan | |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| , | Shut down, Feb 2015 | |
| Climb Bio | Wilmington, DE | Treatments for neuronal Excitability Disorders |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| , | Website copyright 2012 as of 2021, no info | |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Shut down, Aug 2013 | |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group | |
| , | Gone | |
| , | Bought by Norgine, Jul 2017, $342M | |
| , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 | |
| , | Acquired by Lundbeck, Jun 2014, up to $658M | |
| , | Website Expired, Aug-Oct 2018 | |
| , | Acquired by RTI Surgical, Jan 2018 | |
| , | Renamed INOVIQ | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Website Gone, Mar 2017 | |
| Veryan Medical | Galway, Ireland | Helical Stent |
| , | Shut down Apr 2024 | |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| , | Website down Jul 2024 - Dec 2024 | |
| Dante Genomics | L'Aquila, Italy | Whole Genome Sequencing, enabling exploration of health, nutrition, and genetic predispositions. |
| AlphaMab Oncology | Suzhou, China | Biologics |
| , | ||
| , | Merged with Intercell to become Valneva, May 2013 | |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| , | No business filings, 2015-2021 | |
| NeoCura | Beijing, China | Personalized Vaccines |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Vernay | Griffin, GA | Fluid Control Solutions |
| , | Renamed Sierra Oncology, Jan 2017 | |
| , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead | |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| , | Website inactive, Jul 2014 | |
| , | Website down Dec 2023 - Apr 2024 | |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| , | ||
| , | President left in 2011, website still lists him | |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| , | Website Gone, Nov 2016, One Employee | |
| , | Website down Dec 2020 - May 2021 | |
| , | Bought by Piramal | |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| , | Bought by Qiagen, May 2014 | |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| , | Renamed Lenz Therapeutics, Jun 2021 | |
| , | Renamed Orchid Pharma | |
| LakeShore Biopharma | Beijing, China | Vaccines |
| GeneReach Biotechnology | Taichung City , Taiwan | Reagents & Instruments |
| , | Website down May 2021 - Jan 2022 | |
| , | Website down Mar 2021 - Aug 2021 | |
| DifGen Pharmaceuticals | Princeton, NJ | APIs, Formulated Generics |
| Sanofi | Cambridge, MA | Biologics, Vaccines |
| , | Website down Feb 2024 - Jul 2024 | |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| , | Assets sold to Knight Therapeutics, Jun 2015 | |
| , | Website looks pretty terrible | |
| , | ||
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| , | Website gone, CEO gone Oct 2021 | |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| , | Bought by Intercell 2008 | |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| , | Very dated website, 2020-Dec 2024 | |
| , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 | |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| , | Acquired by Elekta, Jan 2005 | |
| Delpharm | Orléans, France | Contract Manufacturing |
| , | Website down Nov 2023 - Mar 2024 | |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| , | Changed name to Windtree Therapeutics, Apr 2016 | |
| CARGO Therapeutics | San Mateo, CA | CAR T Cell Therapy |
| , | Acquired by Exonhit 2012 | |
| , | No info | |
| MantleBio | San Francisco, CA | Data Platform |
| , | Bankruptcy, Feb 2022 | |
| Vésale Bioscience | Mont-St-Guibert, Belgium | Phage Therapy |
| , | Acquired by Cell Biosciences, Sep 2009 | |
| Anumana | Cambridge, MA | AI ECG reading |
| , | big FDA trouble, gone | |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| AssayQuant | Marlboro, MA | Fluorescence Assays |
| , | Website down May 2021 - Sep 2021 | |
| Inhibikase Therapeutics | Lexington, MA | Therapeutic Vaccines |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | ||
| , | Either sold tech or closed down | |
| NeuralInk | Fremont, CA | Neural Implants |
| , | Now part of Flourish Research | |
| , | Acquired by Recursion Pharma, Jul 2020 | |
| , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones | |
| , | Renamed BioFire Diagnostics | |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Bought by Kite Pharma Mar 2015 €20M | |
| , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. | |
| , | No news 2017 - Feb 2024 | |
| , | Website down Feb 2022 - Apr 2022 | |
| , | Website down Jan 2023 - Jul 2023 | |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Zambon | Bresso, Italy | Small Molecules |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| , | Changed name to Zeneca, 1992 | |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| , | Renamed Aanastra | |
| , | Shut down May 2019 | |
| , | Closed Jun 2014 according to NY DOS | |
| , | Shut down Dec 2022 | |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| , | Acquired by EAG, 2006 | |
| , | Renamed Base4, Feb 2023 | |
| , | Merged with Radpharm became CoreLab Partners | |
| Oticon | Somerset, NJ | Hearing Aids |
| Xediton Pharmaceuticals | Ontario, ON | Acquisition, commercialization of various products |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones | |
| , | Acquired by Cytiva, Feb 2021 | |
| , | ||
| , | Acquired by Illumina Jul 2014 | |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| , | Renamed ImmuPharma, 2005 | |
| , | Tech licensed exclusively by W.R. Grace, Oct 2017 | |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones | |
| , | Renamed Cogent Biosciences, Oct 2020 | |
| , | Sold most assets to Mitsubishi Chemical, Jan 2020 | |
| , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 | |
| , | Website down Oct 2023 - Mar 2024 | |
| , | Acquired by Affymetrix, May 2015, $14M | |
| , | Renamed PolyNeuroS | |
| Axplora | Shanghai, China | Purification Systems |
| MSD | Leopardstown, Ireland | Small Molecules |
| Chondropeptix | Maastricht, Netherlands | Peptide for cartilage improvement |
| , | Acquired by C.R. Bard, Dec 2011 | |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| , | Website gone Jun 2020, shell company | |
| , | Bankrupt, seemingly winding down slowly | |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| Neuroservices-Alliance | Bordeaux, France | Translational Data Contract Work |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| , | Acquired by P4 Diagnostix, Feb 2020 | |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| , | Acquired by Elan, 1996 | |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| , | Website down May 2023 - Dec 2023 | |
| , | Renamed TTP Labtech, Sep 2003 | |
| , | Gone before 2019 | |
| , | Acquired by insitro, Oct 2020 | |
| , | Sole employee is a professional board member | |
| , | Bankrupt, Dec 2012 | |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| , | Gone, Oct 2009 | |
| , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips | |
| , | Now part of Analytical Lab Group; fka ATS Labs | |
| , | Acquired by AstraZeneca, Dec 2005, £120M | |
| , | Acquired by Medtronic, Jun 2002, $270M | |
| Scynexis | Jersey City, NJ | Small Molecules |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| , | Changed name to Acerus Pharmaceuticals, Sep 2015 | |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell | |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| , | Gone 2017 | |
| , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots | |
| , | Bought by Aziyo Biologics, May 2017 | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Website Gone, Mar 2017 | |
| , | Product bought by Acelity, Dec 2015 | |
| , | Bought by Merck Dec 2010 | |
| , | Website gone and for sale Nov 2019 | |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 | |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| AGC Biologics | Boulder, CO | Contract Manufacturing - Biologics |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| , | Renamed Uvax Bio? | |
| , | Now Rose Pharma | |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Mabcare Therapeutics | , | |
| , | Website down Jan 2024 - Jul 2024 | |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| , | Website down Nov 2023 - Mar 2024 | |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Hemostemix | Toronto, ON | Autologous Cell Therapy |
| , | Now Nortech Life Sciences | |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| , | Acquired by Richter, Jun 2024 | |
| Ximedica | Providence, RI | Medical Device Services |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| , | Acquired by Fluidigm, Jan 2014, $207M | |
| , | Doesn't seem active, Jul 2022 | |
| , | gone 2018 | |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| , | Shut Down June 2019 | |
| , | ||
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| , | ||
| , | Acquired by Summit Therapeutics, Dec 2017, £10M | |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B | |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| JPT Peptide Technologies | Acton, MA | Peptide products and services |
| , | Gone | |
| , | Merged into PLx Pharma, Apr 2017 | |
| , | Shut down Nov 2018 | |
| , | Founded 2015, No longer listed on Fannin Innovation website | |
| Curia | Albuquerque, NM | Contract Research |
| , | ||
| Syncro Medical | Langhorne, PA | Software development |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| , | Combined with Novartis vaccine unit to become Seqirus | |
| EndoGastric Solutions | Redmond, WA | Surgical and Gastroesophageal Devices |
| , | Renamed Silexion | |
| , | Acquired by North Coast Medical | |
| , | Merged with Sun Pharma, Mar 2015 | |
| , | Closed Jul 2013 | |
| , | Gone 2014? | |
| , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products | |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Symbio | Marl, Germany | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| , | Presumed defunct; Website down Nov 2023 - Feb 2024 | |
| , | Renamed Micron Solutions, Mar 2017 | |
| Hua Medicine | Shanghai, China | Small Molecules |
| , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 | |
| , | ||
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| Excelya | Boulogne, France | Clinical Research |
| , | Shut down 2002, assets sold 2003 | |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| , | IP acquired by Unity HA | |
| , | Renamed NovaSignal | |
| , | Gone Jun 2019 | |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Kargenera | Oxford, UK | NK Cell Therapy |
| , | Acquired by HotSpot Therapeutics, Aug 2019 | |
| , | Renamed Cardiff Oncology, May 2020 | |
| , | Shut Down Jun 2024 | |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| , | Acquired by Trividia Health, Jan 2017 | |
| , | Rebranded as Catheter Precision after Merger | |
| Uneedle | Enschede, Netherlands | Intradermal Needle |
| EnGeneIC | North Ryde, Australia | Nanocell platform for the targeted delivery of chemotherapeutics and functional nucleic acids in cancer |
| , | Acquired by Insmed, Jul 2023 | |
| , | Acquired by Altasciences, Feb 2020 | |
| Bionsight | Chuncheon, Korea | Database For Research |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| , | Changed to Nascent Biotech | |
| , | Reverse Merged with Chosa, Jan 2023 | |
| , | Part of Emcure | |
| Arjo | Addison, IL | Therapeutic Support Systems for immobile people |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| , | ||
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| , | Acquired by AbCellera, Sep 2021 | |
| , | Gone 2019 | |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| , | Acquired by Takeda, Nov 2012 | |
| Astria Therapeutics | Boston, MA | Monoclonal Antibody |
| , | Ichor removed from website as of Dec 2021 | |
| Siga | Corvallis, OR | Small Molecules |
| , | Acquired by Concentra Pharmaceuticals, Feb 2024 | |
| Halloran Consulting Group | Boston, MA | Consulting |
| , | Renamed Dogwood Therapeutics, Oct 2024 | |
| |
Alnwick, UK | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Shut down Jan 2024 | |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| , | Acquired by DePuy, Feb 2022 | |
| , | Merged with Ontorii to form WaVe Life Sciences | |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| , | Acquired by ResMed, Nov 2015 | |
| , | Bought by Thermo Fisher, May 2019, $1.7B | |
| Concinnity Genetics | Edinburgh, UK | RNA-control of gene therapies |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| , | Spam site | |
| , | ||
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| , | Renamed Viventia Biotech, 2000 | |
| , | Acquired by Bioagilytix, Nov 2019 | |
| Novotech | Bangkok, Thailand | Clinical Research |
| , | Acquired by Pharmaron, Feb 2016 | |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| , | Changed to Melinta Therapeutics, Oct 2013 | |
| , | Website exists, no updates since 2001 as of Jun 2019 | |
| , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 | |
| , | Changed name to Forum Pharmaceuticals, Apr 2014 | |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| InBios International | Seattle, WA | Clinical Diagnostics |
| , | Merged with InterVivo, Feb 2022 to become Vivocore | |
| Pioneer GMP Consulting | Auburndale, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| Tirupati | New Delhi, India | Generics |
| , | Renamed Juventas Therapeutics, Apr 2009 | |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| , | Bought by CSL Behring, Jun 2020 | |
| Baxter | Alliston, ON | Medication Delivery |
| , | Bought by VWR Nov 2016 | |
| , | Acquired by Kemwell, Jul 2013 | |
| , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition | |
| , | Acquired by Veraxa Biotech, Jan 2024 | |
| Cornerstone Pharmaceuticals | Cranbury, NJ | Small Molecules, Delivery |
| Baxter | Grosotto, Italy | Medication Delivery |
| Deimos Biosciences | , | |
| , | Website down Mar 2023 - Apr 2024 | |
| Coloplast | North Mankato, MN | Wound care, surgical, bladder, bowel devices |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies | |
| Octapharma | Stockholm, Sweden | Plasma Products |
| , | Acquired by Galera Therapeutics, Dec 2024 | |
| , | Acquired by Abbott Aug 2013, $400M | |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| CureVac | Tübingen, Germany | MRNA treatments |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| , | Changed name to Verastem Oncology, May 2018 | |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| , | No news Oct 2020 - Feb 2025 | |
| , | Changed name to AVEO Oncology, Mar 2005 | |
| , | Bankrupt 2008, executives reincarnated as MultiVir | |
| , | Dissolved, May 2007 | |
| , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 | |
| , | Website gone Nov 2020, not listed in CA business registry | |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Pharmaceutical Calibrations and Instrumentation | Raleigh, NC | Calibration Services |
| Sysmex | Tokyo, Japan | Diagnostics |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| , | Sold main drug in 2013. Don't seem active | |
| , | Changed name to Seres Therapeutics, May 2015 | |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| , | Renamed Synthetic Biologics, Dec 2011 | |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| , | Acquired by Cornerstone Therapeutics 2011 | |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| , | Merged with Crystallics 2016, Renamed Ardena | |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| , | Bought by Novartis, Dec 2016 | |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| , | Acquired by Charles River, Jun 2021, $292M + $57M milestones | |
| , | Division of Predictive Oncology; fka Precision Therapeutics | |
| OD-OS | Irvine, CA | Retinal Laser |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| , | ||
| Sharp | Bethlehem, PA | Contract clinical trial services and commercial packaging services |
| , | Closed 2013 | |
| , | Gone | |
| , | Acquired by Shionogi, 2017 | |
| , | Renamed Circio, Apr 2023 | |
| CEL-SCI | Vienna, VA | Biologics |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back | |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Renamed CQ Medical | |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 | |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| , | Acquired by Fitzgerald Industries, 2007 | |
| , | Website down Mar 2024 - Jul 2024 | |
| ROKIT | Seoul, Korea | Organ Regeneration |
| , | Filing Chapter 11 Bankruptcy, Apr 2024 | |
| , | Acquired by Charles River, Jan 2017 | |
| ProPharma Group | Raleigh, NC | Consulting |
| , | Changed Name to Alvos Therapeutics | |
| , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma | |
| Celerion | Lincoln, NE | Clinical Research |
| Unither Pharmaceuticals | Paris, France | CDMO |
| , | Presumed defunct, Jan 2023; website copyright 2012 | |
| , | Website gone, Sept-Nov 2018 | |
| , | Acquired by Versiti Blood Center, Jul 2019 | |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Hematogenix | Tinley Park, IL | Pharma Services |
| , | Acquired by Natus, Jan 2017 | |
| , | Changed name to Senseonics, Oct 2012 | |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| , | Being folded into new company, Feb 2023 | |
| , | Now part of Hikma | |
| , | Now a licensing outift | |
| , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics | |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| , | Subsumed into parent Ashvattha Therapeutics | |
| , | Acquired by ICI, 1972 | |
| Frenova | Waltham, MA | Renal clinical research |
| , | Acquired by Platine Pharma Services, Jun 2013 | |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Roivant Sciences | Boston, MA | Alliances, Collabs, Partnerships |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Neem Biotech | Blaenau Gwent, UK | Treatments to Counter for Antimicrobial Resistance |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| , | Not sure what happened to them | |
| BennuBio | Albuquerque, NM | Flow Cytometry Equipment |
| Terremoto Biosciences | San Francisco, CA | Covalent Small Molecules |
| , | ||
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| , | Bought by Shionogi | |
| , | Acquired by ERT, May 2015 | |
| , | Renamed ATUM, DEC 2016 | |
| , | Renamed Sampled, Apr 2022 | |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| , | Bought by The Medicines Company | |
| , | ||
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| oncgnostics | Jena, Germany | Diagnostics |
| , | Acquired by Thomas Scientific | |
| , | Sold by Fornix Biosciences to ALK-Abello | |
| Cella Medical Solutions | Murcia, Spain | 3D Surgical Imaging |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| Eterna Therapeutics | San Diego, CA | mRNA Technology |
| , | Website gone Nov 2014 | |
| , | Acquired by Avolynt, Mar 2016 | |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research | |
| , | Merged into New Day Diagnostics, Jul 2023 | |
| , | Renamed Inocras, Mar 2024 | |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| , | Renamed Seaport Diagnostics | |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| Check Cap | Mount Carmel, Israel | Colon cancer screening device |
| BioJiva | , | |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Peptone | London, UK | Translational Biophysics |
| , | Website gone Jul 2015 | |
| , | ||
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| , | Renamed Aerami Therapeutics, Sep 2019 | |
| Purdue Pharma | Stamford, CT | Small Molecules |
| , | Employees all seem gone, Oct 2023 | |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| AktiVax | Broomfield, CO | CDMO |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| , | Acquired by Teva 2006 | |
| Velentium | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| , | Shut Down Dec 2011 | |
| , | No updates on website since 2006 as of Feb 2021 | |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program | |
| , | Company Gone | |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| , | Business Lapsed 2011 | |
| , | Acquired by Telix Pharmaceuticals, May 2024 | |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| , | Renamed Valerio Therapeutics, Jun 2023 | |
| , | ||
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| , | Acquired by Alira Health, Jan 2021 | |
| , | Acquired by Barr Labs 2001 | |
| , | Changed named to Innovation Pharmaceuticals, Jun 2017 | |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Asymmetrex | Boston, MA | Tissue stem cell quantification and analysis |
| Aurlide | Turku, Finland | High Throughput Screening |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| ZMI Pharma | Carlsbad, CA | Opioid Agonist |
| , | ||
| , | Acquired by Gilead Apr 2009, $1.4B | |
| Iktos | Paris, France | AI for New Drug Design |
| , | Acquired by Corin Group, Mar 2019 | |
| , | Bought by Evotec | |
| , | Acquired by Spectrum Pharmaceuticals Sep 2012 | |
| Sanofi | Reading, UK | Small Molecules |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| , | Acquired by Takeda 2011 | |
| Xybion | Quebec City, QC | Cloud LIMS, Quality |
| , | Acquired by Acutus Medical, May 2019 | |
| , | Renamed Jonakayem Pharma - Formulation | |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| , | Website down Oct 2021 - Jul 2022 | |
| , | Now Neovii Biotech | |
| , | Renamed Cassava Sciences, Mar 2019 | |
| , | ||
| , | Renamed Caidya, Oct 2022 | |
| , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 | |
| , | Website down Jan 2022 - Jul 2022 | |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| , | ||
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| , | Acquired by Beckley PsyTech, Oct 2022 | |
| , | Shut down May 2023 | |
| , | ||
| , | Renamed Pendant Biosciences | |
| , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation | |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| , | Renamed Phage Pharmaceuticals | |
| Rallybio | Farmington, CT | Therapeutics |
| , | Renamed Canthera Discovery, Sep 2021 | |
| , | Acquired by Boehringer-Ingelheim, Sep 2021 | |
| , | Gone, Website taken over | |
| Enrich Biosystems | Bradford, CT | Single Cell Isolation |
| , | Gone | |
| , | ||
| , | Website down Oct 2021 - Jul 2022 | |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| , | Renamed Azelon Pharmaceuticals | |
| , | Acquired by BioIVT, Sep 2022; fka Xenotech | |
| , | Shut down Sep 2018 to become Respivant | |
| Corin | Cirencester , UK | Orthopedics |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| , | Acquired by Laborie, Oct 2021 | |
| Bioventus | Cordova, TN | Orthobiologics |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| , | Rebranded as Emery Pharma | |
| , | Shut down Nov 2024 | |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| , | Gone | |
| , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy | |
| SOPHiA GENETICS | Saint Sulpice, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| , | Merged into Endologix, Feb 2016 | |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| , | Bought by Boston Scientific, Feb 2019, $325M | |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| , | Acquired by Crown Bioscience, May 2021 | |
| , | Presumed gone | |
| , | Renamed Voiant Clinical, Sep 2023 | |
| , | Merged with Palleos Healthcare, Jan 2025 | |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| , | ||
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| Accellacare | Hickory, NC | Clinical Research |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| , | Renamed Neurizon Therapeutics, Oct 2024 | |
| , | Website down May 2020 - Feb 2021 | |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| , | Bought by Cardinal Health, May 2014 | |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Acquired by Edwards Lifesciences, Jan 2017, $340M | |
| , | Website Gone, Sep 2015 | |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| , | Acquired by Nevro, Dec 2023, $40M + $35M milestones | |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| bespark*bio | Vienna, Austria | Consulting |
| IMMY | Norman, OK | Fungal Diagnostics |
| , | Bought by SASMAR, Aug 2016 | |
| , | Merged with Innovate Biopharmaceuticals, Apr 2020 | |
| , | Business revoked by CA, 2007 | |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| , | Renamed Visby Medical, Jun 2019 | |
| , | Bankrupt, winding down May 2023 | |
| , | Renamed Macro Biologics, Mar 2023 | |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| , | Website down Jan 2023 - Sep 2023 | |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| , | Merged with Hoechst AGto form Aventis, 1999 | |
| , | Acquired by Fujifilm Diosynth Dec 2014 | |
| , | Website gone, Feb 2015, tech/assets sold to CTX | |
| , | Acquired by Vaxcell Bio, Jan 2025 | |
| KNC Laboratories | Kobe, Japan | Manufacturing Service |
| , | Acquired by Sciele Pharma, Jun 2007 | |
| , | Assets Acquired by Desco, Dec 2013 | |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| , | ||
| , | Acquired by Biofrontera, Mar 2019 | |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| , | Rebranded Pregenen in 2011 | |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Website Gone, Nov 2018 | |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| , | Shut down Apr 2021 | |
| , | Shut Down | |
| LabGenius | London, UK | Synthetic DNA library |
| , | Merged into Perha Pharma | |
| , | Acquired by private equity, combined into Analytical Lab Group | |
| TRIMT | Radeberg, Germany | Targeted Radiopharmaceuticals In Molecular Theranostics |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| , | Website password protected May 2020 - Oct 2020 | |
| Boston Scientific | St. Paul, MN | Medical Devices |
| , | Website down Nov 2024; business filings late Aug 2023 | |
| Microsure | Son, Netherlands | Surgical Robots |
| , | Seems gone, May 2023; aka Medical Creations Inc | |
| , | Ancient website, never registered in CA | |
| Chemestmed | Tartu, Estonia | Epitranscriptomics |
| , | Renamed Inovio Biomedical | |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Endpoint Clinical | San Francisco, CA | Clinical Trial IRT Solutions |
| , | Acquired by Agilent, Mar 2018 | |
| , | Now part of MPE | |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 | |
| , | Website taken over by roofers, Sep 2022 | |
| , | Closed Aug 2017 | |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| , | Website down Feb 2024 - Jul 2024 | |
 |
Alameda, CA | Emery Pharma: CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals). Expertise: HPLC, GC, LC-MS/MS, HRMS, GMP NMR, analytical & bioanalytical, CMC, LBA, micro & cell biology, antimicrobial screening, consulting, R&D & GLP/cGMP across the entire pipeline. |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| , | Merged into ImmunityBio, Apr 2021 | |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| , | Dissolved, Mar 2015 | |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| , | Changed name to Heron Therapeutics Sep 2013 | |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| , | Acquired by Integra Biosciences, Mar 2023 | |
| , | Acquired by CirrusDx, Aug 2022 | |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| , | Part of Paliwoda Group | |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M | |
| Abcam | Cambridge, UK | Antibodies |
| , | ||
| , | Effectively defunct after 2018 | |
| , | Renamed Imunon, Sep 2022 | |
| Visikol | Hampton, NJ | Contract Research, High Content Screening, 3D cell models, ADMET/PKDM |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 | |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Stability Biologics | Nashville, TN | Allografts |
| Curia | Glasgow, UK | Contract Research, Development, Manufacturing |
| , | Business pulled in CA, Sep 2017 | |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| , | Main assets acquired by Ista Pharmaceuticals, May 2002 | |
| , | Seems gone | |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| , | Renamed PlexPharma 2016 | |
| , | Website down Jul 2023 - Oct 2023 | |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| , | Acquired by Perkin-Elmer, Jul 2018 | |
| , | Website gone, business registration not to date Jan 2019 | |
| , | Gone | |
| , | Acquired by Pfizer, Sep 2005 | |
| , | Renamed Thryve Therapeutics, Jul 2022 | |
| Veeva Systems | Radnor, PA | Life Science Software |
| , | Renamed Iksuda Therapeutics, Sep 2018 | |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name | |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| , | Website down Feb 2022 - Jul 2022 | |
| Pencil Biosciences | Alderley Park, UK | Fully synthetic, next-generation non-CRISPR gene editing technology |
| , | Website not working, Sep 2017 | |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| , | Shut Down 2022 | |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| , | Renamed Alaunos Therapeutics, Jan 2022 | |
| , | Acquired by Schering-Plough, Apr 1982 | |
| , | Renamed Cerecin, Oct 2018 | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Website down Jun 2023 - Dec 2023 | |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| , | Changed to Barr Pharmaceuticals | |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Merged with Sirion Aug 2006 | |
| , | Acquired by Gallus | |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| , | Website hawking muscle powder, May 2020 | |
| Vuja De Sciences | Natick, MA | Targeting the unique vulnerability of undetected disseminated tumor cells before they can cause deadly metastatic recurrence |
| , | Renamed MetaVia, Nov 2024 | |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| , | Shut down Oct 2023 | |
| , | Acquired by SparingVision, Apr 2021 | |
| Spear Bio | Woburn, MA | Immunoassays |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| , | Gone 2016 | |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Zevra Therapeutics | Copenhagen, Denmark | Modifications of Existing Drugs |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| , | Closed 2010, Assets acquired by CeeTox | |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| , | Liquidating 2013 | |
| , | Absorbed into Zeiss, Jun 2016 | |
| Globiox | Austin, TX | Quality Compliance Services |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Teva | Toronto, ON | Small Molecules |
| Collagen Solutions | Marton, New Zealand | Collagen |
| , | Product sold to SRS Medical, Nov 2012 | |
| Streck | La Vista, NE | QC & Diagnostic Products |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| Zydus Cadila | Ahmedabad, India | Generics |
| , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics | |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| , | ||
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 | |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Veeva Systems | Toronto, ON | Life Science Software |
| , | Website taken over Feb 2025; Inactive May 2023 | |
| , | ||
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| , | Website gone May 2020 - Sep 2020 | |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Acquired by Alexar Therapeutics, 2014 | |
| , | Website taken over by Online Pharmacy Jan 2020 | |
| , | Website down Nov 2022 - Apr 2023 | |
| , | Website gone, Nov 2015 | |
| Apaxen | Gosselies, Belgium | Treatments for PAH |
| , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M | |
| , | Website down Oct 2022, never registered as a business in Nevada | |
| , | Acquired by diaDexus, Jul 2010 | |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| , | Changed name to Courtagen, switched to Marijuana Testing | |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| , | Bankrupt, shut down Nov 2012 | |
| Infandx | Berlin, Germany | Newborns Diagnostics |
| , | Renamed Biomodal, Apr 2023 | |
| , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad | |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| , | Owned by Cornerstone Therapeutics | |
| Ibex Medical | Brookline, MA | Cancer Diagnostics |
| , | Acquired by Salix Pharmaceuticals, Jan 2014 | |
| , | Acquired by Actavis, Oct 2013 | |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| , | ||
| , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet | |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Pace Analytical | Frontenac, KS | Analytical Testing |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| , | Believed to have been folded into TruCode Gene Repair | |
| , | Acquired by BDO USA, Apr 2019 | |
| , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones | |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Acquired by ALK-Abello, Dec 2016 | |
| Almaden Genomics | Dallas, TX | Cloud-native Bioinformatics Platform |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| Roche | Penzberg, Germany | Diagnostics |
| , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M | |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| , | ||
| , | Bought by Arris Pharmaceuticals 1998 | |
| , | ||
| Huya Bioscience | Shanghai, China | Compound Advancement |
| , | ||
| , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 | |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Gannex Pharma | , | Small Molecules for NASH |
| , | ||
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| , | Gone, 2008 | |
| , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 | |
| , | ||
| , | Website gone Feb 2023; not registered business in CA | |
| , | ||
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences | |
| , | Acquired by OXIS International, Jul 1995 | |
| , | Acquired by Tute Genomice, Nov 2015 | |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| NuChem Sciences | Saint-Laurent, QC | Medical chemistry contract research |
| , | Acquired by Lundbeck, May 2019, $250M | |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| , | Website gone, Nov 2017 | |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| , | Acquired by Roche, May 2021, $1.85B | |
| , | ||
| Waters | Milford, MA | Chromatography & Chemistry |
| , | Acquired by Sana Biotechnology, Oct 2020 | |
| , | Website gone Sep 2017 | |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| , | Renamed Dynamic Cell Therapies, Jun 2022 | |
| Getinge | Mumbai, India | Medical Technology |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| , | Acquired by Miroculus, Apr 2016 | |
| The RND Group | Indianapolis, IN | Medical Device Software |
| , | Bankrupt, dissolved Oct 2017 | |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| , | Shut down Oct 2020 | |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| , | Acquired by Lupin, Oct 2017, $150M | |
| , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics | |
| , | Bought by Zoll Medical, Mar 2015 | |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 | |
| , | Bought by Baxter, Oct 2019, $190M + $40 Milestones | |
| , | Shut down Jul 2014 | |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| , | Website down May 2021 - Sep 2021 | |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| , | ||
| , | Shut down 2013 | |
| , | ||
| , | No website Oct 2019 - Aug 2021 | |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 | |
| , | Website down Feb 2025; Latest news 2013 - as of 2021 | |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| , | Renamed Pareto Bio | |
| , | ||
| , | Gone? Jan 2016 | |
| , | Changed name to Zocere | |
| , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Website gone Apr 2019, Seems defunct | |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| , | Website Gone, Oct 2017 - Dec 2017 | |
| , | Some assets bought by Edwards Lifesciences, Mar 2019 | |
| , | Renamed HDL Therapeutics, Mar 2011 | |
| Bioassay Works | Ijamsville, MD | Immunoassays |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| , | Company or Technology Acquired by Charles River | |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor | |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| , | Acquired by CryoLife, Jan 2016, $130M | |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| QureBio | Shanghai, China | Biologics |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| , | Not registered in MA, 2018 - Feb 2025; sole employee is professor | |
| Tesis Biosciences | Phoenix, AZ | Genetic Testing |
| IQVIA | San Diego, CA | Clinical Research |
| , | Website copyright 2012 as of Apr 2021 | |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Genentech | South SF, CA | Small Molecules, Biologics |
| , | Dissolved Sep 2017 | |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| , | Website hijacked May 2023 - Aug 2023 | |
| , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure | |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| , | Acquired by Alloy Therapeutics, Dec 2021 | |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| , | Closed Sep 2017 | |
| , | Bankrupt 2014 | |
| , | Acquired by Sartorius, Sep 2022, £415M | |
| Neuroservices-Alliance | San Diego, CA | Translational Data Contract Work |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| , | Website down, claimed they were in danger of going out of business in 2016 | |
| , | No business filings May 2022-Sep 2024 | |
| , | Shut down Sep 2023 | |
| Eton Bioscience | Boston , MA | Research Reagents, Kits, Peptides, Services, etc. |
| , | Renamed Vyome Therapeutics | |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| , | Closed late 2016 | |
| , | Website down May 2020 - Feb 2021 | |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| , | ||
| , | ||
| , | Website Down Nov 2022 - Apr 2023 | |
| Omega Therapeutics | Cambridge, MA | Gene Editing |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| , | Bought by Medtronic, Apr 2010, $370M | |
| , | Acquired by Amber Tx, Sep 2023 | |
| EmbarkNeuro | Oakland, CA | Depression Treatments |
| Boostimmune | Seoul, Korea | First-in-class Antibody Therapies, ADCs |
| |
St. Petersburg, FL | Catalent | Gelatin Capsule Manufacturing |
| , | Merged with Zeneca to form AstraZeneca 1998 | |
| , | Acquired by Thermo Fisher, Sep 2012 | |
| , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name | |
| , | Website down, Apr-Dec 2018 | |
| AnRes Clinical | Vejle, Denmark | Clinical Development Consultants |
| Medtronic | Warsaw, IN | Medical Devices |
| , | Seems inactive, Jul 2024 | |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| , | ||
| Verve Therapeutics | Boston, MA | Gene-editing Treatments |
| , | No website Nov 2020 - Jul 2024 | |
| Rain Oncology | Newark, CA | Small Molecules |
| , | Merged with Marina Biotech, Nov 2016 | |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| , | Bought by Merck 2001 | |
| , | Acquired by Cyprotex, Jan 2014 | |
| , | Gone | |
| , | Acquired by Hologic, Aug 2020, $80M + Milestones | |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Kineta | Seattle, WA | Small Molecules |
| , | Acquired by RTI Surgical, Feb 2024 | |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| , | ||
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| , | May technically exist, seem inactive Nov 2020 | |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| DDi | Princeton, NJ | Clinical Software |
| Vesper Medical | Wayne, PA | Venous Stent |
| , | Shut down May 2021 | |
| , | Acquired by Mylan, Apr 1993, $39M | |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| , | Bought by Ipsen, Apr 2019, $1.31B | |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| , | Acquired by United Biosource, May 2010 | |
| Ranomics | Mississauga, ON | Genetic Variant Database |
| , | Merged with INC Research, May 2017, renamed Syneos Health | |
| , | Renamed Quince Therapeutics, Jul 2022 | |
| , | Acquired by Singleron, Mar 2022 | |
| , | Gone 2022 | |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| , | Fka Chiral Quest, effectively gone | |
| , | ||
| Intercept Pharmaceuticals | San Diego, CA | Small Molecules |
| , | Gone 2018 | |
| , | Renamed Mogrify, Mar 2019 | |
| , | Merged with Linical, took name, Jul 2018 | |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| , | Renamed Biopharma PEG Scientific, Jan 2022 | |
| Aprecia Pharmaceuticals | Blue Ash, OH | Zipdose formulation |
| , | ||
| , | Acquired by Safeguard Medical, Jun 2021 | |
| , | Gone 2019 | |
| , | Renamed Osteal Therapeutics | |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| , | Merged with Gyroscope Therapeutics, Apr 2019 | |
| , | Website down Mar 2023 - Sep 2023 | |
| , | No website Mar 2019 - Aug 2020; MA-based | |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| , | Sold to Roivant Sciences, 2017 | |
| , | Became Biodexa Pharmaceuticals, Dec 2022 | |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| , | Renamed Wepredic, Mar 2022 | |
| , | Acquired by Tandem Diabetes, Jan 2023 | |
| Modular Medical | San Diego, CA | Insulin Pump |
| Grifols | Clayton, NC | Biologics |
| Cartherics | Clayton, Australia | Cell Therapy Technology |
| , | ||
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| , | Bought by Zogenix, Sep 2019, $250M + $150M milestones | |
| , | Website Down Jan 2022 - Jun 2022 | |
| , | Now Micelle BioPharma | |
| Expansion Therapeutics | Jupiter, FL | Small Molecules for RNA-mediated Diseases |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| , | Acquired by Gamma Biosciences, Sep 2020 | |
| , | Attempted to sell business, instead only sold parts | |
| , | Liquidating, Aug 2023 | |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| , | Selling assets through chapter 11 bankruptcy, Mar 2023 | |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Sarepta Therapeutics | Cambridge, MA | Biologics |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| NextRNA Therapeutics | Boston, MA | Treatments Targeting Non-Coding RNA |
| , | Failed to raise sufficient funds and dissolved 2008 | |
| , | Acquired by Accuratus Lab Services, Jul 2014 | |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| , | Renamed Nuo Therapeutics, Oct 2014 | |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| Kirgen | Shanghai, China | Lab Supplies |
| , | Acquired by genOway, Sep 2018 | |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| , | ||
| , | Merged with Forte Biosciences, Jun 2020 | |
| , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 | |
| , | Website down Oct 2021 - Dec 2022 | |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| , | Merged with FlashCell, May 2018, became Flash Therapeutics | |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| , | ||
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| CytoVeris | Farmington, CT | AI-powered Cancer Imaging |
| , | Acquired by Medtronic, Sep 2015, $100M | |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| , | Acquired by GHX, Oct 2021 | |
| , | Gone | |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| , | Bought by Novo Nordisk, Jul 2018, up to $800M | |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| , | Website down Nov 2022 - Mar 2023 | |
| , | Website down May 2024 - Jul 2024 | |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| , | Gone as of Oct 2016, likely much sooner, Unknown fate. | |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| CorVista Health | Toronto, ON | Cardiac Diagnostic Platform |
| , | Acquired by ICU Medical, Nov 2019, $75M | |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| , | Bought by Astellas, Dec 2016, $1.4B | |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Acquired by Boston Scientific, Feb 2022, $1.75B | |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight | |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| , | Renamed ZyMot fertility | |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 | |
| , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical | |
| , | Website down Oct 2022 - Mar 2023 | |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| , | Acquired by Pharmaron, Jan 2017 | |
| , | Acquired by Pfizer, Sep 2015 | |
| , | Acquired by W.L. Gore, Aug 2022 | |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| , | ||
| , | Renamed Synthaverse, Jun 2023 | |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen | |
| , | Renamed Adhera Therapeutics, Oct 2018 | |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| , | Liquidating, Apr 2017 | |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Urica Therapeutics | Bay Harbor Islands, FL | Small Molecules for Gout |
| IvWatch | Newport News, VA | IV infiltration detection |
| , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings | |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics | |
| , | ||
| , | Merged with INC Research, May 2017, renamed Syneos Health | |
| , | Acquired by Alcon, Jul 2024, $81M | |
| Vectura | Basel, Switzerland | Inhalers |
| Biohit | Helsinki, Finland | Diagnostics |
| , | Subsidiary of Coghlin Companies | |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| Predictive Oncology | Eagan, MN | AI for biotech |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Virax Biolabs | London, UK | Viral test Kits |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| , | Website down Dec 2021 - Apr 2022 | |
| , | Acquired by Cosmo Pharmaceuticals, Nov 2009 | |
| , | Website gone Dec 2021; Never registered as business in CA | |
| , | Acquired by BioIVT, Sep 2017 | |
| , | No evidence of it ever legally being a business in MA, no website, no news since 2008 | |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| , | Acquired by Elicio Therapeutics, Jun 2023 | |
| , | Renamed Navicus, Mar 2008 | |
| , | Acquired by GSK, Jun 2023, $2B | |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| , | Gone 2019 | |
| , | Website down Dec 2023 - May 2024 | |
| , | ||
| , | Blog spam website now, Mar 2021 | |
| , | Now VG Life Sciences | |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| , | Changed name to NuLife Sciences, Dec 2016 | |
| , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones | |
| Baxter | Cleveland, MS | Medication Delivery |
| , | Website down Jan 2024 - Jul 2024 | |
| , | Merged with Axiogenesis to form Ncardia, Sep 2017 | |
| , | Gone, no info | |
| , | Website gone Jun 2018 | |
| , | Merged with OmniGuide Surgical, 2016 | |
| CNS Healthcare | Orlando, FL | CNS Clinical Research |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| , | No CA business filings Jun 2022 - Jun 2024 | |
| , | Gone 2011 | |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| , | Acquired by Hikma, Apr 2011, $60.5M | |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 | |
| , | Parts of website taken over | |
| , | Website Down May 2024 - Nov 2024 | |
| , | Sold by Solvay to Nitto Denko Avecia Jan 2013 | |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| , | Website gone May 2024 - Sep 2024 | |
| , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals | |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| , | Renamed Momentis Surgical, Jul 2022 | |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| , | Bought by Nantomics, Oct 2016 | |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| PepKon | Louveciennes, France | Peptide Therapies for Cancer |
| , | Seems gone | |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| 89bio | Rehovot, Israel | Liver Treatments |
| , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics | |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| , | Acquired by Ottobock | |
| e-Therapeutics | London, UK | In-Silico Drug Discovery |
| , | Business license revoked Mar 2008 | |
| , | Bought by Sandoz Jul 2012, $1.525B | |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| , | Now ACS Diagnostics | |
| , | Acquired by NanoAntibiotics, Apr 2016 | |
| , | ||
| , | Shut Down 2011 | |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| , | Bought by Alvotech, May 2016 | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Acquired by Jubilant, Jun 2019 | |
| , | Bankrupt, Jul 2008 | |
| , | Shell company | |
| , | Part of Analytical Lab Group | |
| , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical | |
| , | Outdated website, no employees on LI Jun 2023 | |
| , | Acquired by/Merged with Steris | |
| Valneva | Lyon, France | Antibody Discovery |
| , | Renamed ANDE | |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Qualix DoT | Barcelona, Spain | Repurposing Compounds |
| , | Bought by Stryker, Mar 2014 | |
| , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B | |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| , | ||
| Cytokinetics | South SF, CA | Small Molecules |
| , | Renamed Nanosmart Pharmaceuticals, Jun 2006 | |
| , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 | |
| , | Acquired by Retrophin, Dec 2013 | |
| , | Renamed Liminal Biosciences, Oct 2019 | |
| , | ||
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed | |
| , | Website down Aug 2020 - Feb 2021 | |
| , | ||
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| , | ||
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| , | Acquired by Marathon Pharmaceuticals, 2013 | |
| Gynesonics | Redwood City, CA | Uterine fibroids ablation |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| , | Renamed Kinetigen, Jan 2013 | |
| , | Website dated 2008 as of Mar 2018 | |
| , | Renamed Shape Memory Medical | |
| , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 | |
| , | Sold to BioNTech Small Molecules, Apr 2016 | |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| , | Acquired by Recipharm, Feb 2016, $75.5M | |
| , | Website down Sep 2023 - Mar 2024 | |
| Organix | Woburn, MA | Contract Research & Development |
| , | Now Epoch Biosciences | |
| , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone | |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| , | Acquired by Roche, Apr 2007, $56.5M | |
| Alira Health | Boston, MA | Consulting, Clinical Research |
| , | Gone Sep 2017 | |
| , | fka Argenetix, gone | |
| , | Acquired by Qiagen, Jun 2012 | |
| , | Asset acquired 2011, seem defunct | |
| Medtronic | New Haven, CT | Medical Devices |
| , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 | |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Vectura | Wiltshire, UK | Inhalers |
| , | Renamed Nighthawk Biosciences, Apr 2022 | |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies | |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Durect | Cupertino, CA | Drug Delivery |
| , | Dissolved Sep 2016; fka NovaRX | |
| , | Acquired by Siemens, Sep 2000, $700M | |
| Puzzle Medical | Montréal, QC | Transcatheter heart pump |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Life Edit Therapeutics | Durham, NC | Next-generation gene editing platform |
| , | Website down Jul 2021 - Dec 2021 | |
| , | Website gone Feb 2024 | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Renamed Adela | |
| Adventris Pharmaceuticals | San Francisco, CA | Cancer Immunotherapy |
| , | Website down Apr 2021 - Sep 2021 | |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| C4X Discovery | Manchester, UK | In-Silico Drug Design |
| , | Employees all gone, may be a professor's side deal | |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| , | Tiny startup that went nowhere | |
| , | Acquired by Proteintech, Apr 2018 | |
| , | Shut down Jul 2024 | |
| , | Merged with Akebia, Dec 2018, took Akebia name | |
| , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 | |
| , | Shut down pre-Aug 2005 | |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| , | Renamed Galvanize Therapeutics, Spr 2022 | |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Joylux | Seattle, WA | Vaginal Rejuvenation |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Website down Jun 2024 - Nov 2024 | |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| , | Sartorius acquired majority stake, Jul 2021 | |
| , | Renamed CNBX Pharmaceuticals, Mar 2022 | |
| , | Renamed Mateon Therapeutics, Jun 2016 | |
| |
Wuppertal, Germany | WuXi Biologics is a biologics & vaccines CRDMO for antibodies, ADCs, recombinant proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Getinge | Solna, Sweden | Medical Technology |
| , | Gone Oct 2019 | |
| , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 | |
| Sarepta Therapeutics | Andover, MA | Biologics |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Stago | Franconville, France | Diagnostics |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| , | Now RevDia | |
| , | Acquired by Novartis, Jan 1997 | |
| Neurophet | Seoul, Korea | AI-Image Processing |
| , | Acquired by Boston Scientific Dec 2004 | |
| , | Dissolved Sep 2024 | |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| , | Acquired by AMRI, 2015, $174M | |
| Kookmin Bio | Jeonju, Korea | Microbiome Research |
| Janssen Pharmaceuticals | Ambler, PA | Small Molecules, Biologics |
| Mosaic Therapeutics | Cambridge, UK | Oncology therapies for biomarker-stratified populations |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| ProPhet Bio | , | AI Drug Discovery |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess | |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| DT MedTech | MC's-Hertogenbosch, Netherlands | Ankle Replacements |
| , | Closed Dec 2011 | |
| PPD | Middleton, WI | Contract R & D, Consulting |
| OncoLize | Maastricht, Netherlands | Polymer-based Hydrogel |
| Genopore | Yavne, Israel | Protein Identification |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Acquired by Fluidigm, Feb 2020 | |
| , | ||
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| , | Renamed RxSight, Feb 2017 | |
| , | Bought by Bionomics, Sep 2012, $10M | |
| , | No progress 2014-2024 | |
| , | Renamed Psomagen, 2019 | |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| , | Domain taken over Oct 2021 - Jan 2022 | |
| Medtronic | Dublin, Ireland | Medical Devices |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot | |
| Novo Nordisk | Beijing, China | Inflammation Research |
| , | Acquired by Clinical Data, Jun 2005 | |
| , | Shut down Jan 2021; fka Coferon | |
| , | Website down Jul 2022 - Oct 2022 | |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| , | Website down Dec 2023 - May 2024 | |
| , | Acquired by Lilly, Aug 2023, $1.9B | |
| Interius BioTherapeutics | Philadelphia, PA | Novel methods for in vivo cell-specific gene delivery |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| , | Acquired by DanDrit Biotechnology, Feb 2018 | |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings | |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| , | Bought by Astellas May 2011 | |
| , | Gone | |
| Organon (2) | Jersey City, NJ | Women's Health |
| Wepredic | Saint Gregorie, France | Cell Lines |
| , | Website gone, Jan 2019 | |
| , | Acquired by Gate Neurosciences, Feb 2025 | |
| , | Renamed Medfiles, Jan 2023 | |
| , | ||
| , | Renamed CMIC | |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| , | Renamed AAT Bioquest | |
| , | Renamed Fortress Biotech, Apr 2015 | |
| , | Renamed Nykode Therapeutics | |
| , | Employee who left 2.5 yrs ago still on website Apr 2021 | |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Shut down Sep 2021 | |
| GT Apeiron | Shanghai, China | AI Drug Development |
| , | Website Gone, no info | |
| , | Website being update Jan 2023 - May 2023 | |
| Everzom | Paris, France | Exosome Therapeutics |
| Lupin | Maharashtra, India | Generics |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| , | Acquired by Fujifilm, Jun 2018 | |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Palleon Pharmaceuticals | Waltham, MA | Glycoimmune Checkpoint Inhibitors |
| Novogene | Beijing, China | Genomic Services |
| , | Acquired by Gruppo Ferrer, Jun 2016 | |
| , | Acquired by Thermo Fisher, Apr 2016, $1.3B | |
| Stago | Marseille, France | Diagnostics |
| , | Dissolved | |
| , | Website down, Jan 2024 - Jul 2024 | |
| , | Acquired by Quotient Clinical, Feb 2017 | |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| , | Website down May 2021 - Oct 2021 | |
| OnQuality Pharmaceuticals | Shanghai, China | Treatments for cancer side effects |
| , | Gone 2022 | |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| , | Acquired by DCN Dx, Jun 2021 | |
| , | Gone | |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Fluent BioSciences | Watertown, MA | Single Cell Analysis Without Complex Instrumentation |
| , | Merged into iCare, Apr 2020 | |
| Invenra | Madison, WI | Antibodies and their derivatives |
| , | Renamed NavigoProteins, Feb 2017 | |
| , | Renamed ErVimmune, Oct 2023 | |
| , | Bought by AngioDynamics 2007 | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Website gone Nov 2017 | |
| , | ||
| , | Bought by Allergan, Feb 2017, $2.4B | |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics | |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| , | Acquired by Merck, Nov 2020, $425M | |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| WaveBreak | Cambridge, UK | Small Molecules Targeting Protein Mis-Folding |
| , | Renamed ZyVersa Therapeutics, May 2019 | |
| , | Acquired by Crede Capital Group, Jan 2015. Website gone. | |
| , | Now BIND Therapeutics | |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| , | Acquired by Cytyc, Apr 2007 | |
| , | Renamed GBI Biomanufacturing | |
| , | ||
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| , | Acquired by Veristat, Feb 2021 | |
| , | Acquired by BALT, Sep 2016 | |
| , | Acquired by Castle Creek Biosciences, Jan 2022 | |
| , | Renamed Metabiomics | |
| , | ||
| , | ||
| , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 | |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| , | Renamed Lineage Cell Therapeutics, Aug 2019 | |
| Virscio | New Haven, CT | Contract Research & Consulting |
| , | Acquired by Werfen, 2008 | |
| , | Acquired by Dante Labs, Oct 2021 | |
| , | Website down Nov 2023 - Mar 2024 | |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| , | ||
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific | |
| Admescope | Oulu, Finland | ADME-tox services |
| , | Bought by Aduro Biotech, Sep 2015, $32.5M | |
| Getinge | Vendôme, France | Medical Technology |
| Outset Medical | San Jose, CA | Dialysis Device |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| , | Website gone, Jan 2018 | |
| Baxter | Deerfield, IL | Medication Delivery |
| , | Acquired by Eisai, Apr 2007 | |
| , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 | |
| , | Assets bought by OPK Biotech, Aug 2009 | |
| , | Renamed Aran Biomedical | |
| Notch Therapeutics | Toronto, ON | Gene-modified T cell therapy |
| , | No website Dec 2019 - Dec 2020 | |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| , | Gone Nov 2017 | |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| , | Website Gone | |
| , | Shut down 2018 | |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| , | ||
| , | Bought by Telerx, Apr 2013 | |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| , | Bought by DNA electronics, Jan 2015, $24M | |
| , | Seems like one guy | |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Virtici | Seattle, WA | Product / Company Incubator |
| , | Merged with Syrxx as Trilogy Pharmaceuticals | |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based | |
| , | No news 2019 - Jan 2025 | |
| Cellergy Pharma | Wilmington, DE | CAR T |
| , | Acquired by Corza Medical, Dec 2021 | |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Yao Pharma | Chongqing, China | APIs, Generics |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Kymanox | Luxembourg, Luxembourg | Life Science Consulting |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| , | Acquired by Sosei Group, Jun 2010, $5.6M | |
| Dornier MedTech | Rome, Italy | Urology Devices |
| , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business | |
| , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR | |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| , | Acquired by Acasti, Aug 2021 | |
| , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. | |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| , | Website down Mar 2024 - Jul 2024 | |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones | |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| , | Renamed Alpha-9 Oncology, Jan 2024 | |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| , | Bought by SuperGen | |
| Medicure | Holetown, Barbados | Small Molecule |
| , | Acquired by ICT | |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| , | Changed name to Groove Biopharma, Jun 2011 | |
| , | Gone, unknown | |
| , | Shut Down 2011 | |
| , | Seems inactive Nov 2023 | |
| , | CEO gone, website down Jun 2021 - Jul 2021 | |
| Pace Analytical | Indianapolis, IN | Analytical Testing |
| , | Acquired by Miltenyi Biotech, Apr 2014 | |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| SteriPack Contract Manufacturing | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Baxter | Marion, NC | Medication Delivery |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| , | Merged with Venus Medtech, Dec 2018 | |
| , | Gone | |
| , | Out of business (Bloomberg BusinessWeek) | |
| LAVA Therapeutics | Utrecht, Netherlands | Bi-specific Antibodies |
| , | Shut down, Dec 2017 | |
| , | Renamed Vium | |
| , | ||
| , | No website, no info Apr 2019 - Jan 2025 | |
| SmartPharm Therapeutics | Cambridge, MA | Production of biologics within patients via gene therapy |
| , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 | |
| , | Website down Jul 2022 - Nov 2022 | |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| , | Website down Apr 2024 - Aug 2024 | |
| , | ||
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| , | Acquired by Boston Scientific, Nov 2012, $425M | |
| Boston Scientific | Galway, Ireland | Medical Devices |
| SanBio BV | Uden, Netherlands | Antibodies |
| Synergistix | Sunrise, FL | CRM software |
| , | Shut down Aug 2023 | |
| PELOBIOTECH | Planegg-Martinsried, Germany | Primary cells, stem cells, media |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Abbott | Sunnyvale, CA | Drug-Eluting Stents |
| Novigenix | Epalinges, Switzerland | Molecular Diagnostics |
| , | Acquired by Viracta Therapeutics, Feb 2021 | |
| , | Website down Feb 2022 - Jul 2022 | |
| Karma Biotechnologies | Torrance, CA | Biologic Drug Delivery |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| , | ||
| , | ||
| Cytiva | Tokyo, Japan | Medical Devices |
| , | ||
| , | Acquired by Sartorious, Sep 2023, €2.4B | |
| , | Acquired RuiYi, rebranded as RuiYi | |
| , | Renamed QuantaBio | |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| , | Renamed Standard BioTools, Jan 2022 | |
| , | One person, no news 2013 - Jun 2023 | |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Eton Bioscience | Durham, NC | Research Reagents, Kits, Peptides, Services, etc. |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| ZipBio | Seattle, WA | Compact Proteins |
| , | Now Tactic | |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| , | ||
| Veeva Systems | Dublin, OH | Life Science Software |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name | |
| , | Acquired by Cordis, Jul 2006, up to $90M | |
| |
Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| , | Renamed Altiris Pharmaceuticals | |
| , | Bought by Mylan, Jun 2016 | |
| , | Acquired by Shire, Mar 1997 | |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| , | Gone | |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| HOPO Therapeutics | Berkeley, CA | Heavy Metal Poisoning Prevention |
| , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money | |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| SteriPack Contract Manufacturing | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| , | No news 2018 -2023 | |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| , | Liquidated Mar 2003 | |
| Artera | Los Altos, CA | AI Diagnostics |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| , | Bought by Grifols | |
| StemBioSys | San Antonio, TX | Stem Cells |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| , | ||
| , | Acquired by Ginkgo Bioworks, Feb 2024 | |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| , | ||
| , | Gone | |
| , | ||
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| , | Renamed OncXerna, Sep 2020 | |
| , | ||
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| , | ||
| , | Bought by Adicet Bio, Jan 2016 | |
| , | Acquired by Sanara MedTech, Apr 2022 | |
| BeOne Medicines | Emeryville, CA | Small Molecules, Monoclonal Antibodies |
| , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 | |
| , | Merged with Medifacts, became CoreLab Partners | |
| , | Gone 2010 | |
| , | Website under construction Dec 2019 - Apr 2020 | |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals | |
| Brain Vision | Morrisville, NC | EEG Systems |
| , | Website gone, Apr 2019 | |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Abbott | Alameda, CA | Diabetes Care |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| , | Renamed Eleva, May 2020 | |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| Brii Biosciences | Durham, NC | Bringing medicines to Chinese market |
| , | Acquired by Perkin Elmer, May 2011, $?? | |
| , | Acquired by Zimmer Biomet, Jun 2016 | |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| , | Shell Company, Dec 2019 | |
| , | Merging into Dare Bioscience, May 2018 | |
| , | ||
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| , | Seems inactive, Restructuring 2010. Website copyright 2008. | |
| Ignis Therapeutics | , | |
| Inversago Pharma | Montréal, QC | Small Molecules |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| XyloCor Therapeutics | Wayne, PA | Gene Therapy |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| , | Website taken over, Mar 2019 | |
| Osivax | Lyon, France | Universal Flu Vaccine |
| , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 | |
| , | Assets acquired by Inovio, Mar 2016, $5.5M | |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | ||
| Design Pharmaceuticals | Cambridge, MA | Small Molecule Drug & Design |
| , | Acquired by Pioneer Surgical, Oct 2007 | |
| preclinics | Eystrup, Germany | Contract Research |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| VedaLab | Cerisé, France | IVD rapid tests |
| PercayAI | Chesterfield, MO | AI for Drug Discovery Software |
| , | ||
| , | Acquired by Catalent, Jun 2021 | |
| , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 | |
| , | Bankrupt 2015 | |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| , | Website gone Feb 2019 | |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| , | Closed down | |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| , | Website taken over Jul 2020 | |
| , | Website gone Jul 2019, possibly subsumed into parent Stemedica | |
| , | Renamed Istisso | |
| , | Website dated 2011 and looks circa 2002 | |
| , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe | |
| Veracyte | Austin, TX | Cytology Diagnostics |
| , | Shut down Dec 2021 | |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery |
| , | ||
| Otsuka | Rockville, MD | Small Molecules |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| BlueJay Therapeutics | San Francisco, CA | Monoclonal Antibody, Small Molecule |
| , | Lost court case to Celgene, Jul 2016, doesn't seem active | |
| , | Shut down 2020 | |
| , | Shut down Nov 2020 | |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| , | Website down/taken over Oct 2021 - Dec 2021 | |
| , | Acquired by PL Developments, Jul 2017 | |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Specifica | Santa Fe, NM | Antibody discovery |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| , | Website taken over Sep 2020 | |
| , | Changed name to PAI Life Sciences, Apr 2014 | |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| , | Assets Acquired by Corden Pharm, Oct 2013 | |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| |
Winchester, KY | Catalent | Contract Manufacturing |
| Santen | Nara, Japan | Ophthalmics |
| , | Gone post 2018 | |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| Adragos Pharma | Munich, Germany | Formulation, Manufacturing, Analytical, PD, Tech Transfer, Stability |
| Cellix Biosciences | Hyderabad, India | Drug Development & Design |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical | |
| , | Became holding company for Theramlin | |
| , | ||
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| , | Acquired by Sunovion, Oct 2016, $635M | |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Licensed IP to Cellular Life Sciences | |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Shut down Dec 2020 | |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| , | Assets acquired by Paladin Labs, Jun 2013 | |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| , | Acquired by Lallemand Dec 2013 | |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| , | Acquired by J&J, Jun 2017, $30B | |
| , | Website down Feb 2021; Did not file 2018 or 2019 annual report | |
| , | Website down Mar 2020 - Feb 2021 | |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| , | Became part of Roche in 1994 | |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| Amryt Pharma | London, UK | Orphan Specialty Drugs |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| , | Acquired by Roche, Jan 2008 $3.4B | |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| , | Gone 2019? | |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| , | Rebranded as Novum Medical, 2021 | |
| Sanovel | Istanbul, Turkey | Generics |
| Vynamic | Philadelphia, PA | Healthcare, Life Science Management Consulting |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| , | Acquired by Harmony Biosciences, Apr 2024 | |
| , | Website down Aug 2023 - Apr 2024; fka AgaMatrix | |
| , | Acquired by Antisoma, Jun 2008 | |
| , | Acquired by Mesa Biotech, Apr 2010 | |
| , | Acquired by Ardena, May 2018 | |
| , | Renamed IQVIA, Nov 2017 | |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics | |
| Biograph 55 | , | |
| , | Renamed TruCode Gene Repair, Oct 2017 | |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Peplib | Metuchen, NJ | Peptides |
| MicroPort | Saluggia, Italy | Medical Devices |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Bought by Charles River Labs, Mar 2014, $179M | |
| , | Acquired by Transport Pharmaceuticals, Aug 2006 | |
| , | Acquired by Artio Medical, Jul 2020 | |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| , | Acquired by Beckman Coulter, Jan 2019 | |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| , | Bought by Amgen, Aug 2013, $10.4B | |
| Cavion | Charlottesville, VA | Neurologic diseases and cancer |
| , | Renamed SetPoint Medical, Jul 2008 | |
| , | Website gone Feb 2021 | |
| , | Bought by Abbott 2010 | |
| , | Presumed Gone | |
| , | ||
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Cajal Neuroscience | Seattle, WA | Neurodegenerative Therapies |
| , | Acquired by Calliditas, Nov 2020 | |
| LumiThera | Pulsbo, WA | Photobiomodulation |
| , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics | |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| , | Acquired by Collegium, Sep 2024 | |
| , | Website down Aug 2022 - Jan 2023 | |
| , | Acquired by Micrologix Biotech, Sep 2002, $320M | |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Celerion | Zurich, Switzerland | Clinical Research |
| , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions | |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| , | Acquired by Endetec@Veolia, 2011 | |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| , | Acquired by Clinipace, Apr 2015 | |
| Ingenio Diagnostics | Hamilton, NJ | Clinical diagnostic laboratory services and specialty testing |
| , | Acquired by Exact Sciences, Oct 2018 | |
| , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones | |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| TC Biopharm | Edinburgh, UK | Cell-based Immunotherapy |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| Benchmark Research | San Angelo, TX | Clinical Research |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Effectively bankrupt, Feb 2018 | |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| , | Gone 2001 | |
| , | Website down May 2021 - Oct 2021 | |
| , | ||
| , | Basically everyone is gone. Email asking about company bounced | |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| , | Website down Jun 2021 - Sep 2021, no info | |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Website Gone, failed to file annual report with LA | |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| , | Acquired by Ethypharm, Mar 2017 | |
| , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B | |
| Fibriant | Leiden, Netherlands | Recombinant fibrin sealant to treat surgical bleeding (R&D) |
| , | Bought by Lannett, 2007 | |
| , | Acquired by Novavax, Jun 2013 | |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| , | No News Apr 2020 - Jan 2025 | |
| , | Website down Sep 2020; No one works at this fulltime | |
| Staburo | München, Germany | Clinical Services |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 | |
| Saghmos Therapeutics | , | |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 | |
| , | Not active business according to MD DOS, website gone | |
| , | Acquired by United Healthcare, Dec 2023, $91M | |
| , | Dissolved, May 2023; Successor to Naurex | |
| , | Renamed Splice Bio, Sep 2020 | |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| , | Renamed Amolyt Pharma | |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| , | Website down Apr 2023 - Sep 2023 | |
| DiaCarta | Pleasanton, CA | Molecular Diagnostics Tests |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| , | Acquired by Lumibird, Jun 2020 | |
| , | Gone by 2017 | |
| , | Dissolved, Dec 2020 | |
| , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket | |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| , | Merged with Athenagen to become CoMentis, Aug 2006 | |
| , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 | |
| , | Insolvency Proceedings | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Changed name to Immutep, Nov 2017 | |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Aixial Group | VILLEURBANNE, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | ||
| , | Website Gone, Jan 2016; no employees on LinkedIn | |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| , | Acquired Spinal Elements, Apr 2017, took their name | |
| Instil Bio | Dallas, TX | Cell Therapy |
| , | Website hijacked Sep 2020 | |
| AstronauTx | London, UK | Alzheimer's Treatments |
| , | Seems out of business as of Jan 2019 | |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| , | Acquired by Aceragen, Nov 2021 | |
| KeChow Pharma | , China | Small Molecules and others |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Getinge | Wayne, NJ | Medical Technology |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| , | Now Flen Health | |
| , | Website down Mar 2023 - Sep 2023 | |
| , | Acquired by Shire, 2008 | |
| , | Acquired by LivaNova, Feb 2018 | |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| , | Acquired by Vertex, Sep 2019, $950M | |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| AAX Biotech | Stockholm, Sweden | Next-gen Antibody Therapeutics |
| , | Renamed Xeris Biopharma, Oct 2021 | |
| , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 | |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| , | Bankrupt, product sold to Stryker | |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| , | Bought by Quintiles, Nov 2011 | |
| , | Renamed Shalby Advanced Technologies, Jan 2023 | |
| , | Acquired by NeoGenomics, May 2021, $390M | |
| , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 | |
| , | Acquired by Olympus, Aug 2020 | |
| , | Renamed New Day Diagnostics, Jan 2023 | |
| , | Bought by Eli Lilly, Jul 2010, $380M | |
| , | Acquired by Nanobac Pharmaceuticals, Feb 2008 | |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Paris, | ||
| Lynk Pharmaceuticals | Hangzhou City, China | Kinase Inhibitor |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| , | Renamed Verndari, Apr 2016 | |
| Aliri | Loos, France | Contract Mass Spec |
| Alkem Labs | Mumbai, India | Generics |
| , | Now Jubilant Hollister-Stier | |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 | |
| Boston Scientific | Cork, Ireland | Medical Devices |
| Pharmaron | Hertfordshire , UK | R&D Services |
| , | Subsumed into Paragon Biosciences | |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| , | Switched to energy sector | |
| , | Shut down May 2019 | |
| , | Website down/hijacked Sep 2021 - Dec 2021 | |
| , | Acquired by Bard, Jul 2004 | |
| , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 | |
| , | Website gone Dec 2018 | |
| , | Website gone, reported as closed on Google, Jan 2024 | |
| , | Changed name to Bioptix, Dec 2016 | |
| , | Acquired by Velocity Clinical, Jun 2019 | |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| , | No news, Feb 2018 - Dec 2025 | |
| Natech Plastics | Ronkonkoma, NY | Contract medical device diagnostic components |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| , | Renamed Yaso Therapeutics | |
| , | ||
| , | Acquired by Bio-Rad, Aug 2004, $32M | |
| , | Bought by Amgen 2006, Sep 2006, $380M | |
| , | ||
| , | Closed 2005 | |
| , | Merged with Windtree Labs Jan 2019 | |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| , | Gone, 2017 | |
| , | Acquired by Perkin Elmer, Oct 2020, $383M | |
| , | ||
| , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 | |
| , | Part of R&D Systems | |
| , | Acquired by AbSci, Jan 2021 | |
| , | Website down Jun 2021 - Oct 2021 | |
| , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 | |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Getinge | Suzhou, China | Medical Technology |
| , | Merged with Cornerstone Therapeutics | |
| , | Centessa Company | |
| , | Liquidating Aug 2021 | |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Bao Pharmaceuticals | Shanghai, China | |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Genesis MedTech | Singapore, Singapore | Surgical Devices |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| , | Bought by BMS, 1990; sold to CONMED Dec 1997 | |
| icometrix | Leuven, Belgium | Imaging AI |
| , | Bought by Applied Biosystems 2006 | |
| , | ||
| Nanobiotix | Paris, France | Nanoparticles |
| , | ||
| Bioserv America | San Diego, CA | Bulk formulation, filtration, filling, stoppering, lyophilization services, labeling, finished goods assembly, kitting and packaging |
| AcuraStem | Pasadena, CA | Repurposing approved products for ALS |
| , | No website, very little info | |
| JUVIC | Seoul, Korea | Microneedle Technology |
| , | Bought by LabCorp, Sep 2016, $371M | |
| , | Acquired by 858 Therapeutics, Sep 2021 | |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| , | Website down Jan 2023 - Jul 2023 | |
| , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 | |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| , | Bought by Invitae, Apr 2021, $200M | |
| , | Acquired by Wacker, May 2018 | |
| , | Changed name to Gossamer Bio, Dec 2017 | |
| , | ||
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| , | Now ProteinSimple | |
| , | Shut down Dec 2019 | |
| MOgene | St. Louis, MO | Genomic Services |
| , | Website down Sep 2023 - Mar 2024 | |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Abalone Bio | Emeryville , CA | Antibody Therapies |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B | |
| , | Gone 2017 | |
| Moon Surgical | Paris, France | Robotic Surgery System |
| Erbe Elektromedizin | Tübingen , Germany | Surgical Systems |
| , | Website not updated in 6 years, person who left in 2014 still listed on team | |
| , | ||
| , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application | |
| , | Gone Nov 2020 | |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| , | Merged with Enzyvant, Dec 2022 | |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Metacrine | San Ramon, CA | Metabolic diseases |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| , | Website down Aug 2024 - Feb 2025 | |
| , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 | |
| BioMarin Pharmaceutical | London, UK | Biologics |
| , | Website down Jul 2024, hijacked Aug 2024 | |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones | |
| MSD | Brinny, Ireland | Small Molecules |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| , | Website down Sep 2022, no real employees | |
| , | Renamed Biosplice Therapeutics, Apr 2021 | |
| , | Not a registered business in CA Feb 2025 | |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| , | Acquired by Abiomed, Jun 2021 | |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| , | Acquired by Stedical Scientific, Aug 2019 | |
| , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences | |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| , | Acquired by Quintiles, Aug 2012 | |
| , | Merged with Flamingo Theraputics, Mar 2023 | |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| , | Assets Acquired by PTC Therapeutics, Oct 2019 | |
| , | Website gone Oct 2018 | |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| Hummingbird Diagnostics | Heidelberg, Germany | Blood-borne miRNA Diagnostics |
| , | Bought by Philips, Dec 2014, $1.2B | |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Bowil Biotech | Wladyslawowo, Poland | Biocellulose |
| Ipsen | Sant Feliu De Llobregat, Spain | Small Molecules, Biologics |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology | |
| , | Website down Jun 2024 - Nov 2024 | |
| , | Renamed Antiva Biosciences | |
| Laboratorio Reig Jofre | Monaco, Monaco | Pharma manufacturing (antibiotics/injectable |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| NantHealth | El Segundo, CA | Diagnostics |
| , | Changed name to Anchor Therapeutics, Feb 2010 | |
| AMS Biotechnology | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| ProPharma Group | Bozeman, MT | Consulting |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Allarity Therapeutics | Boston, MA | Cancer Treatments with Companion Diagnostics |
| , | Merged with TopoTarget to become Onxeo | |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| KYM Biosciences | , | |
| , | Bought by Recipharm, Apr 2016, $205M | |
| , | Acquired by Precision for Medicine, May 2016 | |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| , | German Aptamer company, not sure of fate | |
| , | Website down Jan 2021 - May 2021; fka Virion Health | |
| AATec Medical | Munich, Germany | AAT Therapies |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Parallel Biosystems | Cambridge, MA | Human Immune Organoids for Drug Discovery |
| Axial Therapeutics | Woburn, MA | Neurology-Microbiome research |
| , | Shut down | |
| VIVEbiotech | Donostia · San Sebastian, Spain | Lentiviral CDMO |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| Curia | West Lafayette, IN | Analytical Services |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclincal, Toxicology and Pharmacology laboratory. |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| Basecamp Research | London, UK | AI-Biology Data |
| , | Embroiled in lawsuit with Arriva in 2006, seems gone | |
| , | Website gone Feb 2020 - Mar 2021 | |
| , | Bankrupt, Aug 2018, selling all assets | |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| , | Now Triangle Research Labs | |
| , | Renamed Adheron Therapeutics | |
| , | Gone 2014 | |
| , | Acquired by Thermo Fisher, Apr 2013, $13.6B | |
| , | Website down Nov 2019 - Feb 2019 | |
| Mesenbio | York, UK | Cellular -derived Extracellular Vesicles |
| , | Renamed Hemanext, Oct 2017 | |
| , | Renamed Mercury Bio, Mar 2023 | |
| Vivifi Life Sciences | Bangalore, India | Generics |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| LenioBio | Aachen, Germany | Cell-free protein expression kit |
| , | Acquired by Baxter, Apr 2014, $70M+ | |
| , | No website Aug 2019 - Aug 2021; single person outfit in Maine | |
| , | Website down Feb 2021 - Jul 2021 | |
| , | Renamed Clario, Nov 2021 | |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| , | Effectively acquired by Santen, 2008 | |
| , | Renamed Character Bio, May 2022 | |
| Molecular Partners | Zürich, Switzerland | Biologics |
| , | Website down Jul 2022 - Nov 2022; aka Friley Consulting | |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| , | Changed name to mdRNA, Nov 2007 | |
| , | Rebranded as Cleave Therapeutics | |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| , | Website down Jul 2022 - Nov 2022 | |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| , | Seems gone as of Dec 2019 | |
| , | Acquired by Teleflex, Dec 2016 | |
| , | Tech acquired by Conventus Orthopedics, Dec 2019 | |
| , | Acquired by BMS, Jul 2016, $95M + $425M milestones | |
| , | Gone 2014 | |
| , | Bought by Shire Jan 2014 | |
| , | Company appears to be gone, Oct 2016 | |
| , | Bought by GSK | |
| , | believe dba Chimera Bioengineering | |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| , | Acquired by ImaSight in reverse merger, Jun 2008 | |
| , | Bought by Bio-rad | |
| , | ||
| , | Only employee has four other jobs | |
| , | Gone, facility acquired by Cronos group | |
| , | Renamed Biosynth, Sep 2022 | |
| GSK | Palo Alto, CA | Drug Delivery |
| , | ||
| , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 | |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| , | Merged with Rules-Based Medicine, Nov 2006 | |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| DK Diagnostics | São Paulo, Brazil | Diagnostics |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| , | Renamed Microbia | |
| , | Renamed Zikani Therapeutics 2019 | |
| , | Website down Apr 2021 - Jun 2021 | |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| , | Acquired by Imperative Care, Jul 2021 | |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| , | Dissolved, Sep 2009 | |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| , | ||
| , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 | |
| , | Renamed Fresh Tracks Therapeutics, Sep 2022 | |
| , | Rebranded as mtibio | |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Azzur | Morrisville, NC | Consulting |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| , | Sold to MBL International | |
| Epic Pharma | Laurelton, NY | Generics |
| Ergomed | Mumbai, India | Clinical Research |
| , | Bought by Alere, Jul 2015, $60M | |
| , | No website, Nov 2018 - May 2023; "Stealth" | |
| , | Website down Jan 2022 - Jul 2022 | |
| BioAgilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| , | Assets Sold Off 2009 | |
| , | Acquired by Qiagen, May 2022 | |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Centricity Research | Toronto, ON | Clinical Research |
| , | Assets bought by Glycotope Biotechnology 2007 | |
| ReproSource | Marlborough, MA | Fertility Testing |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| , | Acquired by LGM Pharma, Jul 2020 | |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 | |
| , | Rebranded as Tribe Clinical | |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| , | Acquired by Zydus Cadila, 2019 | |
| , | Gone Jul 2018 | |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| , | Acquired by Life Technologies 2012 | |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| , | Fka Athenagen, site gone Oct 2017 | |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| , | Took parent company name, BioTissue, Jun 2022 | |
| , | Bought by Watson | |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| , | Merged with StemoniX, Mar 2021 to become Vyant Bio | |
| , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido | |
| , | Website down Dec 2023 - Feb 2024; academic startup by a professor | |
| Capstan Therapeutics | San Diego, CA | Lipid Nanoparticles to enable engineering or ablation of pathogenic cells in the body |
| , | Now just Strides | |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| , | Website down Jan 2024 - Jul 2024 | |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules |
| , | Acquired by Gyrus, 2005, $500M | |
| , | ||
| , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase | |
| , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR | |
| , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical | |
| , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones | |
| Grunenthal | Aachen, Germany | Small molecules |
| |
Canton, MA | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| , | part of SK pharmteco | |
| , | Website from 2004 | |
| , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition | |
| , | Likely gone. No plans to bring back website. | |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | ||
| , | Website down Jun 2024 - Dec 2024 | |
| , | ||
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| , | No website, Jul 2019 - May 2023 | |
| , | Website gone, Mar 2019 | |
| Hyku Biosciences | Lexington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Sequana Medical | Munich, Germany | Implantable pump systems |
| Adaptix | Oxford, UK | Medical imaging |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Tevard Biosciences | Cambridge, MA | tRNA-based Gene Therapies |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| , | Acquired by Sanofi Pasteur, Sep 2010, $55M | |
| FHC | Bowdoin, ME | Medical Devices |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| , | No website Jun 2019, founded 1997 | |
| Roche | Pleasanton, CA | Diagnostics |
| , | No website Oct 2019 - Dec 2023 | |
| , | Gone 2018 | |
| , | Renamed Microline Surgical, Sep 2009 | |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| , | Merged with ARS Pharmaceuticals, Nov 2022 | |
| , | Acquired by Laurus Labs, Jan 2021 | |
| Think Bioscience | Boulder, CO | Small Molecules Targeting Undruggable Proteins |
| , | Website down Oct 2023 - Mar 2024 | |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| , | Acquired by Bard, Oct 2012, $140M | |
| , | Website down, Employees all gone, Aug 2023 | |
| , | Dissolved, Nov 2014 | |
| Inscopix | Mountain View, CA | Miniature Microscope |
| , | Merged with SightLife Surgical, Apr 2014 | |
| , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 | |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| , | Now Sophiris Bio | |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| , | Acquired by Vertex Pharmaceuticals, 2001 | |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Sanovel | Silivri, Turkey | Generics |
| Oncodesign Services | Dijon, France | Preclinical services |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Inference | Pune, India | Clinical Trial Services |
| , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website | |
| , | Liquidated Oct 2007 | |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Marea Therapeutics | San Francisco, CA | Treatments for Cardiometabolic Diseases |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| , | Apparently acquired by Celgene | |
| , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 | |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| , | Acquired by BMS, Mar 2016, $225 + $375 milestone | |
| CorWave | Clichy, France | Blood Pumps |
| , | Absurd website 2020-2023 | |
| , | Merged with Glaxo Wellcome in 2000 to form GSK | |
| Sanofi | Midrand, South Africa | Biologics |
| Hologic | Beijing, China | Diagnostic, Imaging |
| PDC*line Pharma | La Tronche, France | Novel class of off-the-shelf cancer immunotherapies based on a proprietary Plasmacytoid Dendritic Cell line pre-loaded with peptides |
| , | Acquired by Pfizer | |
| Dio Tree | Nazareth, Israel | Small Molecules for Ovarian Cancer |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | ||
| NAKI Therapeutics | Summit, NJ | Cell Therapy |
| , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 | |
| , | Renamed Eurofins Discoverx | |
| , | Renamed Miravo Healthcare, Dec 2020 | |
| , | Acquired by TE Connectivity, Feb 2015, $190M | |
| I-Mab Biopharma | Rockville, MD | Biologics |
| , | Website gone, Nov 2018 | |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| , | Website Gone, Jan 2019 | |
| , | Website down Jul 2019 - Oct 2019 | |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| , | Website down May 2023 - Dec 2023 | |
| , | Merged into Paratek, Oct 2014 | |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| IQVIA | Durham, NC | Clinical Research |
| , | Website down Jul 2024 - Dec 2024 | |
| , | Acquired by Korber Group, Jun 2020 | |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| , | Merged with Capnia, Mar 2017 | |
| , | Website gone Apr 2021 - Jun 2021 | |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| , | ||
| , | Acquired by LumiThera, Mar 2022 | |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| , | Renamed Renovaro Biosciences, Aug 2023 | |
| Cellular Dynamics | Madison, WI | Induced Pluripotent Stem Cells |
| , | Renamed Hyalex Orthopaedics, May 2017 | |
| , | Gone, don’t know where | |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| , | Renamed Cellular Therapeutics Ltd, Mar 2018 | |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| , | Website redirecting to a stay-at-home mom page | |
| , | Doesn't seem active, LI page gone Nov 2023 | |
| , | Acquired by PuraCap, Mar 2016 | |
| , | Website taken over by spam, marked as closed Feb 2025 | |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| , | Website taken over, Dec 2021 | |
| Medtronic | Carlsbad, CA | Medical Devices |
| , | Renamed Hyku Biosciences, Aug 2023 | |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| , | Website gone Apr 2020 | |
| , | Shut down May 2015, no money | |
| Almac | Durham, NC | Pharmaceutical Services |
| , | Renamed Hygeia Therapeutics, Dec 2007 | |
| Tri-Pac | South Bend, IN | Contract Filling |
| , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 | |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 | |
| Delpharm | Gaillard, France | Contract Manufacturing |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| Biolojic Design | Boston, MA | AI-based Multibody technology |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| , | Acquired by Qiagen, Jan 2016 | |
| , | ||
| Inspirata | North York, ON | Cancer Insights |
| , | Website down Mar 2021 - Sep 2021 | |
| , | Acquired and renamed, pivoted to mining | |
| , | Acquired by private equity to be relaunched as InClinica | |
| , | ||
| , | Bought by Catalent, Oct 2017 | |
| , | Renamed Beyond Air, Jun 2019 | |
| Hope Medicine | Pudong, China | Antibody Therapy |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| CTK Biotech | Poway, CA | Diagnostics |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| , | Became subsidiary of Kyn Therapeutics | |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 | |
| , | Not a registered business in NY, website gone Jan 2019 | |
| , | Acquired by Thermo Fisher, Apr 2021, $17.4B | |
| , | Acquired by AbbVie, Jul 2019 | |
| , | Renamed Inso Biosciences | |
| , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) | |
| , | Website down Dec 2020 - May 2021 | |
| , | Merged with 3Scan to become Strateos, Jun 2019 | |
| KinCon biolabs | Innsbruck, Austria | Live-cell Activity Biosensors |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| , | Website down Aug 2022 - Feb 2023 | |
| |
Frankfurt, Germany | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | ||
| , | Website down Jan 2023 - Jul 2023 | |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| Teva | West Chester, PA | Small Molecules |
| , | Gone | |
| , | Split to become Xyphos and Pylum Biosciences, Nov 2017 | |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| , | Acquired by Amgen, Apr 2021, $55M + $666 milestones | |
| , | Acquired by Celgene, Jan 2018, $9B | |
| , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE | |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| , | Website five years stale, ancient-looking Mar 2024 | |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| , | Acquired by BioServe, 2007 | |
| , | Website down Feb 2023 - Jul 2023 | |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| , | Bought by Medtronic, Jul 2015, $235M | |
| , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals | |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| , | Shut down Mar 2021 | |
| , | No news 2020-2024 | |
| , | Major assets bought by Kyocera Medical, Jan 2019 | |
| , | Website gone | |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| PredxBio | Pittsburgh, PA | Image Analysis |
| , | Acquired by Neumora, Oct 2021 | |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| , | One employee left Oct 2022 after having received $18M in 2010 | |
| , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 | |
| , | ||
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Rho | Durham, NC | Clinical Research |
| |
Kirchberg, Switzerland | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Website down May 2023 - Dec 2023 | |
| , | Bought by Benitec Biopharma Oct 2012 | |
| , | Renamed Prostatype Genomics | |
| , | Now Irvine Clinical Research | |
| , | Bought by 3M, Feb 2015 | |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| , | Acquired by WCG, Mar 2016 | |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| , | Bought by Wyeth, Sep 1996 | |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| , | Website redirecting to a plea for investments, Oct 2015 | |
| Lumicell | Newton, MA | Cancer imaging device technology |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| , | Acquired by Isto Biologics, Apr 2022 | |
| , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 | |
| , | Acquired by rubber company, 2003 | |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| Abbott | Ettlingen, Germany | Stents |
| , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 | |
| , | Merged with Idera Pharmaceuticals, 2004 | |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| Roche | Mississauga, ON | Small Molecules |
| , | Website down May 2022 - Oct 2022 | |
| , | Acquired by Life Technologies, Oct 2012 | |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| , | No news Oct 2020 - Feb 2025 | |
| , | Gone 2005 | |
| , | Closed May 2018 | |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| Pharmathen | Marousi, Greece | Generics |
| , | Bought by eurofins, Apr 2011, $200M | |
| , | ||
| , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 | |
| Evotec | Toulouse, France | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Bought by Sanofi Pasteur, $276M, Sep 2008 | |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| , | Website down Jan 2022 - Jul 2022 | |
| , | Acquired by Danaher, Sep 2012 | |
| Dermavant Sciences | Long Beach, CA | Small Molecules for Dermatology Indications |
| Gilead | Mississauga, ON | Small Molecules |
| iTeos Therapeutics | Gosselies, Belgium | Cancer Immunotherapy |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| OYC Americas | Vista, CA | Enzymes, proteins, antibodies, substrates |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| , | Bought by Astellas, May 2017, €500M | |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 | |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| C -Biomex | Pohang, Korea | Radionuclides, peptide |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| , | ||
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules |
| , | Pivoted to supplements | |
| Alvotech | Zurich, Switzerland | Biosimilars |
| |
Worms, Germany | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| , | Acquired by Natus, Sep 2009 | |
| , | Bankrupt Dec 2012 | |
| , | now Aytu BioPharma | |
| , | Gone, Apr 2016? | |
| Vincerx Pharma | Palo Alto, CA | Small Molecules |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| , | ||
| Quanticate | Raleigh, NC | Clinical Research |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| , | Subsumed into Liveleaf | |
| , | Business Surrendered, Sep 2019 | |
| , | Gone | |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| , | Acquired by PierianDx, Oct 2016 | |
| Abbott | Singapore, Singapore | Diagnostics |
| , | Website Gone Jan 2019 | |
| , | ||
| , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. | |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| , | Acquired by IDBS, Nov 2021 | |
| Enteris BioPharma | Boonton, NJ | Formulation Solutions |
| Mitologics | Créteil, France | CRO mitochondrial effects of chemicals or biology |
| , | ||
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| , | Acquired by Eurofins, Jul 2017; fka Discoverx | |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| BioCentriq | Newark, NJ | Boutique cell therapy CDMO with a proven track record of successful clinical manufacturing. |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| , | Acquired by Avanos Medical, Apr 2016, $174M | |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| , | Acquired by Aptuit, Sep 2005 | |
| , | Filed Chapter 11 bankruptcy, Nov 2019 | |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Palisade Bio | Carlsbad, CA | Small Molecules |
| , | Acquired by CardioVasc, Apr 2007 | |
| Linical | Stuart, FL | Clinical Research |
| , | Website down Dec 2022 - Apr 2023 | |
 |
Stirling, UK | Symbiosis provides fill/finish manufacturing slots with expertise of vaccines, mAbs and more, offering integrated services to get drug products from manufacture to release. |
| , | Sold Assets to Merck 2011 | |
| , | Bought by BMS, Sep 2007, $415M | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Website gone, Aug 2017 | |
| , | Website down Aug 2023 - Jan 2024 | |
| , | Renamed Epeius Biotechnologies, May 2001 | |
| , | Bought by Novartis, Jul 2008, $880M | |
| , | Sold assets 2016, Website Gone, Dec 2018 | |
| , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 | |
| , | Now Cellgro | |
| , | ||
| , | Seems to have pivoted to Crypto | |
| , | Gone 2013? | |
| Boston Pharmaceuticals | Cambridge, MA | Acquisition of products |
| , | Does not appear active, Apr 2019 | |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| , | Liquidating, Hemophilia assets bought by Baxter | |
| , | Acquired by Unchained Labs, Jul 2023 | |
| PharmAbcine | Daejeon, Korea | Antibodies |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| , | Acquired by Precision for Medicine, Aug 2019 | |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| , | Acquired by Abbott, Oct 2017, $4.6B | |
| RNAnalytics | Tulin, Austria | Analysis methods for lipid nanoparticles |
| , | ||
| Zai Lab | Palo Alto, CA | Small Molecules |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Delve Bio | San Francisco, CA | Metagenomic NGS Diagnostics |
| , | Chapter 11 Bankruptcy, Sep 2019 | |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| , | Seems Gone, no employees on LI, website gone | |
| , | Acquired by Teleflex, Sep 2017, $1.1B | |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| Quantificare | Suwanee, GA | Medical Imaging |
| , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte | |
| , | Bought by CytoBioscience, Dec 2016 | |
| , | Renamed Oscient Pharmaceuticals, May 2004 | |
| , | No Website Dec 2018 - May 2023 | |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| , | Merged with Tripos to become Certara | |
| , | Renamed Eterna Therapeutics, Oct 2022 | |
| , | Gone | |
| , | Bought by Graceway | |
| , | Now Zalicus | |
| Roche | Mannheim, Germany | Diagnostics |
| , | Ceased Operation | |
| , | Bought by AbbVie, $21B May 2015 | |
| , | Renamed Interpace Biosciences, Nov 2019 | |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX | |
| , | Acquired by Merit Medical, Oct 2022 | |
| , | Acquired by RQM+, May 2023 | |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| , | Website for sale Feb 2021; fka Critical Outcome Technologies | |
| Athira Pharma | Bothell, WA | Small Molecules |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| , | Not registered in GA, no news 2015-2024 | |
| , | Acquired by Trinity Biotech, Oct 2024, $3M | |
| , | Renamed Avive Solutions, Sep 2019 | |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| , | Acquired by ten23, Oct 2021 | |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| , | Active as of 2017, Severely dated website, Jan 2019 | |
| Helsinn | Iselin, NJ | Small Molecules |
| , | Acquired by CTI Jul 2007 | |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | ||
| Poxel | Lyon, France | Drugs for metabolic disease |
| , | Renamed Quotient Bioresearch | |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Website down Jul 2022 - Nov 2022 | |
| Transcenta | Suzhou, China | Antibody Therapeutics |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| , | Bankruptcy Liquidation 2012 | |
| , | Aquired by Dotmatics, 2022; aka Statistical Solutions | |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| |
Kaiseraugst, Switzerland | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| , | Acquired by Exelixis, Sep 2004, $22.3M | |
| , | Merged with Plurinomics to form Ncardia, Sep 2017 | |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| , | Renamed NeuoKaire, May 2024 | |
| , | Dissolving, Nov 2023 | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Merged with BioCopy, Apr 2024 | |
| , | ||
| CSL Behring | Bradley, IL | Biologics |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| , | ||
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| , | Sole product sold to Southmedic, Dec 2017 | |
| , | Website Gone Jul 2015 | |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| , | Acquired by Emergent Biosolutions, Dec 2013, $222M | |
| , | ||
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| , | No website Dec 2019 - Aug 2021 | |
| , | Renamed Emerald Bioscience | |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| , | Exceptionally outdated website Jun 2019 | |
| , | Website gone Sep 2022 - Jan 2023 | |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| , | No idea what happened | |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| , | Renamed EyeGaze | |
| , | Renamed Zyla Life Sciences, May 2019 | |
| , | Acquired by Lantheus, Jul 2024 | |
| Nalo Therapeutics | Palo Alto, CA | Small Molecules |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Siemens Healthineers | Mountain View, CA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| , | Renamed Strongbridge Biopharma Sep 2015 | |
| MSN Labs | Hyderabad, India | Generics |
| , | Acquired by 10x Genomics, Dec 2018 | |
| , | Bankrupt and liquidated, May 2013 | |
| Apotex | Toronto, ON | Small Molecule Generics |
| , | ||
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| , | ||
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| , | Shut down 2018 | |
| , | Gone 2019 | |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| , | Renamed Clarify medical | |
| , | Acquired by Beckman Coulter, Sep 2022 | |
| , | Website down Jul 2021 - Dec 2021 | |
| , | Acquired by Oracle, Oct 2018 | |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| |
Hesperia, CA | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| , | Acquired by Baxter, Nov 2002, $50M+ | |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Signant Health | Horsham, PA | eClinical Solutions |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| , | Became part of Q2 Lab Solutions, Feb 2024 | |
| BioDot | Irvine, CA | Equipment |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| , | Renamed bit bio, Oct 2019 | |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| , | Renamed Iambic Therapeutics, Oct 2023 | |
| , | Dissolved, May 2012 | |
| Natco Pharma | Telangana, India | Generics, APIs, Contract Manufacturing |
| , | Gone 2017 | |
| , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 | |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Trajectum Pharma | Utrecht, Netherlands | mRNA Therapies for Autoimmune Conditions |
| Innogenix | Amityville, NY | Generics |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| , | Acquired by Teva, Oct 2011, $6.8B | |
| , | Website down, Mar-Apr 2018 | |
| , | Closed Jan 2018 | |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| , | Renamed Tierra Biosciences, Sep 2018 | |
| , | Website down Oct 2021 - Mar 2022 | |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| , | Bought by Victory Pharmaceuticals 2011 | |
| , | Employees all gone, Feb 2022 | |
| , | ||
| , | Assets Acquired by Exelixis, May 2021 | |
| , | Renamed Cyclarity Therapeutics, Jun 2022 | |
| , | Acquired by Evotec, Dec 2016, £ 55.7M | |
| , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals | |
| , | Shut Down, 2021 | |
| SUN Bioscience | Lausanne, Switzerland | Organoids |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Was part of Fougera which was acquired by Sandoz, Jul 2012 | |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| , | Acquired by Tissue Regnix, Aug 2017 | |
| , | Website Gone Jul 2015 | |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| , | Now part of Antibodies Inc | |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| , | Website Taken Over | |
| , | Working under Q-State Biosciences | |
| , | Part of Frenelle Pharma, Feb 2025 | |
| , | Acquired by Alcon, Nov 2022, $770M | |
| , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy | |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B | |
| , | ||
| NextPhase Medical Devices | Waldwick, NJ | Medical Device Contract Manufacturing |
| , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. | |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 | |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| , | Website Down Jan 2022 - Jul 2022 | |
| , | Seems shut down 2019 | |
| , | Renamed Synvista Therapeutics, Jan 2009 | |
| , | Merged with Ocugen, Sep 2019 after exploring strategic options | |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| , | Dated website, no employee on LI Feb 2025, no news 2022-2025 | |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| , | Acquired by Teleflex Jun 2012 | |
| PhoreMost | Cambridge, UK | Biologics |
| , | Renamed Verisante | |
| , | Renamed KALA BIO | |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Vetter | Chicago, IL | Aseptic Filling |
| , | Now refer to themselves as TPI | |
| , | Renamed Statera Biopharma, Sep 2021 | |
| , | ||
| |
Alameda, CA | Emery Pharma: CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals). Expertise: HPLC, GC, LC-MS/MS, HRMS, GMP NMR, analytical & bioanalytical, CMC, LBA, micro & cell biology, antimicrobial screening, consulting, R&D & GLP/cGMP across the entire pipeline. |
| , | Website copyright 2008 as of Mar 2019 | |
| , | Acquired by Cytel, Jun 2019 | |
| Novotech | Sydney, Australia | Clinical Research |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| Helsinn | Lugano, Switzerland | Small Molecules |
| , | ||
| , | Renamed Iterion Therapeutics, Nov 2018 | |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| , | Acquired by WCG, Jul 2021 | |
| , | Renamed Epirium, Dec 2019 | |
| Excision BioTherapeutics | San Francisco, CA | Gene Editing |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Novozymes | Davis, CA | Enzymes, Biologic Reagents |
| , | No website Nov 2018 - Mar 2020; SBIR grant | |
| Bioventus | Durham, NC | Orthobiologics |
| , | Bought by Piramal | |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| , | Website gone Sep 2022, Employees all gone | |
| Biofarma Pharmaceutical | Istanbul, Turkey | Small Molecules |
| , | Shut down Apr 2017 | |
| , | Acquired by Arthrex, Jul 2017 | |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| , | Shutting down Jan 2021 | |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| , | Website taken over by porn, May 2020 | |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B | |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| , | Acquired by Brooks Life Sciences, Nov 2015 | |
| Integer | Alden, NY | Medical & Surgical Devices |
| , | Acquired by Pharmaron, Feb 2017 | |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Syantra | Calgary, AB | Breast cancer blood test |
| , | Website down Apr 2024 - Aug 2024 | |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| , | Renamed NIOX, Sep 2022 | |
| Inspirata | Tampa, FL | Cancer Insights |
| , | ||
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| , | Acquired by Depuy Synthes, Dec 2021 | |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| , | Website down Dec 2017-Feb 2018 | |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| , | Renamed Quiver Biosciences, May 2023 | |
| , | Bankrupt, Jul 2023, Liquidating | |
| Heraeus Medical | Yardley, PA | Medical Devices |
| , | Bought by Actient Pharmaceuticals Dec 2011 | |
| , | ||
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| , | ||
| , | Website down Jun 2023 - Dec 2023 | |
| , | Dissolved, May 2015 | |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| , | ||
| NorthSea Therapeutics | Amsterdam, Netherlands | Small Molecule |
| , | Founder left Dec 2017, Site gone Apr 2018 | |
| Pieris Pharmaceuticals | Boston, MA | Modified Anticalins |
| Calyx Pharma | Mumbai, India | APIs |
| , | Website gone Jun 2023 - Sep 2023 | |
| , | Website down Nov 2023 - Jul 2024 | |
| Ergomed | London, UK | Clinical Research |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| , | Renamed Venaxis Dec 2012 | |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| , | Website under construction, Sep 2021 - Jun 2022 | |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Nanoscope Therapeutics | Dallas, TX | AAV-delivered opsin |
| , | No employees on LI. Not sure active | |
| Xcell Science | Novato, CA | Stem cell lines, cellular research models |
| , | ||
| Microfluidics | Westwood, MA | High shear fluid processors |
| Gangagen | Bangalore , India | Ectolysins |
| , | Acquired by Illumina, May 2024 | |
| , | Acquired by Perkin Elmer, Aug 2016 | |
| , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M | |
| , | Seems to be Dante Genomics now | |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| , | Website four years since update, no employees on LI | |
| |
Schorndorf, Germany | Catalent | Dosage Form Development |
| Genedata | Basel, Switzerland | Bioinformatics |
| , | Website gone Sep 2017 | |
| , | 29 yr old company in RD stage | |
| , | ||
| , | Website gone Mar 2024 | |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) | |
| vTv Therapeutics | High Point, NC | Small molecules |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| Veryan Medical | Horsham, UK | Helical Stent |
| , | Renamed Ioniq Sciences, May 2020 | |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| ABEC | Springfield, MO | Biopharmaceutical Process Equipment |
| , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 | |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy | |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| , | Moved out of country, Feb 2018, no website, presumed gone | |
| , | Bought by BMS, Oct 2001, $7.8B | |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| , | ||
| , | Company dissolved due to intellectual property issues, 2015 | |
| , | Now Janssen Pharmaceuticals | |
| , | Changed name to Teligent, Oct 2015 | |
 |
Belfast, UK | ARC Regulatory is a specialist regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| NERx Biosciences | Indianapolis, IN | Small molecule cancer drugs |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| , | Renamed Scinai Immunotherapeutics, Sep 2023 | |
| Ximedica | Plymouth, MN | Medical Device Services |
| , | Acquired by Cyrus Biotechnology, Dec 2021 | |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| , | Closed Aug 2015 | |
| , | Acquired by Pfizer, Oct 2020 | |
| , | ||
| , | Website gone, Oct 2019, not a registered business in CA | |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| , | Acquired by CooperSurgical, Jun 2016 | |
| , | Bought by Ethicon | |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| Kuano | Cambridge, UK | AI Drug Discovery |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Analog Pharma | Princeton, NJ | Generics |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| , | Acquired by CSL Behring, Aug 2017 | |
| , | Website down Jul 2022 - Nov 2022 | |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| , | Merged with Tempest Therapeutics, Jun 2021 | |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| , | Website down Aug 2023 - Dec 2023 | |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| , | Acquired and renamed Beryllium | |
| , | Renamed Vivance, Oct 2024 | |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; | |
| , | Acquired by Investors, Jun 2024 | |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| , | ||
| , | Bought by Abcam, Mar 2012, $155M | |
| , | Website gone May 2021 - Aug 2021 | |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Releviate Therapeutics | San Diego, CA | Monoclonal Antibody for Neuro pain |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| , | Acquired by MDS, Aug 2005 | |
| , | Acquired by NAMSA, Mar 2022 | |
| , | Acquired by NantCell, Jun 2015 | |
| , | ||
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 | |
| , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 | |
| , | Acquired by Hologic, 2020 | |
| , | ||
| , | Gone Nov 2009 | |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| Sciomics | Neckargemünd bei Heidelberg, Germany | Custom microarrays |
| , | Bought by Pfizer, Jun 2016, $5.2B | |
| , | Merged with Wyeth 1943 | |
| , | Website absurdly outdated, Dec 2020 - Jan 2022 | |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| , | Acquired by Satellos by Reverse Merger, Aug 2021 | |
| , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 | |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| ZY Therapeutics | Cary, NC | Drug Delivery Technology |
| Discover Echo | San Diego, CA | Microscopy |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Acquired by Philips, Aug 2018 | |
| , | Acquired by Qiagen, Jan 2019 | |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| , | Acquired by Boston Scientific, Apr 2018, $275M | |
| , | Acquired by Histogenics | |
| , | Bought by Valeant Dec 2008, Wound down late 2013 | |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| , | ||
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 | |
| , | Parent acquired by Huvepharma, Jan 2018 | |
| Baxter | Shanghai, China | Medication Delivery |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| , | ||
| Vunthera | Utecht, Netherlands | Therapeutic Antibody for CMV |
| , | Acquired by GBF Group Pharma, 2017 | |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| , | Renamed ReactDx | |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| , | Acquired by ICN Pharmaceuticals, Oct 2002 | |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| , | Assets Acquired by Cellistic, Apr 2024 | |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| , | Merged into new company, Apr 2019 | |
| Defender Pharmaceuticals | St. Louis, MO | Intranasal Scopolamine |
| , | Website taken over Sep 2021 | |
| Genmab | Plainsboro, NJ | Biologics |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Orbis Medicines | Copenhagen, Denmark | Oral Macrocyclic Drug Delivery |
| , | Shut down, Jul 2015 | |
| , | Gone | |
| , | Seems to have been subsumed into Altasciences | |
| Viva Pharmaceutical | Richmond, BC | Custom Manufacturing |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| , | ||
| Shionogi | Florham Park, NJ | Small Molecules |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| , | ||
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 | |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| CellCarta | Montréal, QC | Clinical Research |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| , | Bankrupt Dec 2010 | |
| CanBas | Shizuoka, Japan | Small Molecules |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| , | Website down May 2022 | |
| , | Gone | |
| , | Acquired by Meda, Aug 2005, €750M | |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| , | Acquired by Alvogen $186M, Jun 2014 | |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| , | ||
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| , | Renamed Alumis, Jan 2022 | |
| , | Shut down 2018 | |
| , | Website gone Jul 2021 | |
| , | Acquired by UCB, May 2004, $2.7B | |
| Laverock Therapeutics | Stevenage, UK | Programmable Cell Therapies |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Freenome | South SF, CA | Cancer Diagnostics |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Novozymes | Paraná, Brazil | Enzymes |
| Becton Dickinson | Sparks Glencoe, MD | Lots of Biotechnology Products |
| , | Rolled into parent, SMC | |
| , | Bought by Repligen, Aug 2017, $359M | |
| , | Main asset acquired by Intellus Medical, Jun 2016 | |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| , | Acquired by Cordis, Oct 2023, $235M | |
| , | Website down May 2020 - Dec 2020 | |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| , | Changed name to Anesiva Jun 2006 | |
| , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) | |
| , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones | |
| Cardiovascular Systems Inc | St. Paul, MN | Peripheral Artery Disease Devices |
| , | Website down Nov 2022 - Apr 2023 | |
| , | Closed 2008 | |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| , | Website down Jan 2019 | |
| Autocam Medical | São Paulo, Brazil | Precision-Machined Medical Devices, Implants |
| Magnetic Insight | Alameda, CA | Magnetic Particle Imaging |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| Acumed | Madrid, Spain | Medical Implants |
| , | Website gone Aug 2018 | |
| , | Acquired by Allergan, Oct 2003 | |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| , | Now part of eStudysite | |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna | |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| , | No updates 2016-2023; Only product is a topical salicylic acid | |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| AKIGAI | Oslo, Norway | EGFR-inhibitors for neuropathic pain |
| , | Acquired by Evolva, Nov 2014, $59M stock | |
| , | No real employees, website under construction perpetually | |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| Jyong Biotech | , | Plant-derived Drugs |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| , | Dissolved Dec 2003 | |
| , | Acquired by Stryker, May 2018 | |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| , | ||
| Aesculap Biologics | Breinigsville, PA | Surgical Instruments, Medical Devices |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| , | Product acquired by AstraZeneca, Sep 2020; Residential address | |
| Genovis | Cambridge, MA | Nanoparticles |
| Bryllan | Brighton, MI | Contract Manufacturing |
| , | Acquired by MGI Pharma, Sep 2004, $50M | |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Delpharm | Lille, France | Contract Manufacturing |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| , | Bought by Syngenta, Sep 2012 | |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Elektrofi | Boston, MA | Biologics Formulation |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| , | ||
| Medeloop | Menlo Park, CA | AI Clinical Research Platform |
| , | Acquired by Sotera, Feb 2015 | |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Jet Life Sciences | Hyderabad, India | APIs |
| , | ||
| neoX Biotech | Shanghai, China | Computational design for novel drug research and development |
| , | Shut down Feb 2021 | |
| , | Renamed Medcura, Dec 2019 | |
| Priosh PharmaChem | Baar, Switzerland | Drug Discovery, Formulation Development, Clinical Research, APIs |
| , | Acquired by Medtronic, Jan 2020 | |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| , | Bought by Sanofi-Aventis, Apr 2009, $500M | |
| IQVIA | Durham, NC | Clinical Research |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| , | Website down Sep 2021 - Feb 2022 | |
| , | Website Gone | |
| , | Rebranded as Avvio Medical, Jun 2024 | |
| , | Acquired by Pfizer (2005) then sold to Durata (2010) | |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Acquired by Takeda, Jul 2018, $630M | |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 | |
| , | Acquired by Thermo Fisher, Jul 2008 | |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| , | ||
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| , | Renamed Raptamer Discovery Group | |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| , | ||
| , | Bankrupt Jul 2014, ceased operations, terminated almost all employees | |
| , | Business lapsed in CA, website last updated 2010 | |
| Velsera | Belgrade, Serbia | Biomedical data analysis platform |
| , | Bought by Neogen, Jan 2014 | |
| , | ||
| , | Acquired by Oncos Therapeutics, Jun 2015 | |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| , | Website hijacked, Feb 2025 | |
| , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 | |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| , | Acquired by Bio-Techne, 2014 | |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| , | Founded 2012, no additional business filing as of Dec 2019 | |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| , | Acquired by AOP, Jan 2022 | |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| NovaMedica | Moscow, Russia | Small Molecules |
| , | Website down Feb 2023 - Jul 2023 | |
| BioSciencesCorp | Vallejo, CA | Biologics Services & Consulting |
| GSK | Hamilton, MT | Vaccine additive |
| BIT Analytical Instruments | Montpellier, France | Contract Manufacturing, Develepment |
| Iterum Therapeutics | Old Saybrook, CT | Anti-infectives |
| Affluent Medical | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Nanosyn | Santa Clara, CA | Medicinal chemistry, drug screening |
| , | Bought by Merck 2006, Sold to Alnylam Jan 2012 | |
| , | Acquired by AXIM Biotechnologies, Jan 2020 | |
| , | Dissolved Jun 2021 | |
| , | Website Gone, nothing online about them | |
| , | Business not yet registered in CA Dec 2017-Oct 2024 | |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| , | ||
| , | ||
| , | ||
| , | ||
| , | Acquired by Alexion, May 2018, $855M | |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| , | Website taken over or pivoted, down Nov 2022 | |
| , | Shut down Oct 2014 | |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Avinger | Redwood City, CA | Arterial surgical devices |
| , | Acquired by Vifor Pharma | |
| Symberix | Durham, NC | Small molecules that act upon human microbiome |
| , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 | |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds | |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| , | Now vantix DIAGNOSTICS | |
| Asymbio | Jinshan, China | Biologics CDMO |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| , | Website Gone, April-Oct 2016 | |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Oxehealth | Abingdon, UK | Cameras as health monitors |
| , | Website down Mar 2020 - Aug 2020 | |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| , | Merged into Assertio, May 2020 | |
| , | Bankrupt 2007 | |
| , | Merged with Mereo, Apr 2019 | |
| , | Licensed out product, laid off entire workforce, Dec 2022 | |
| Berkshire Sterile Manufacturing | Lee, MA | Fill Finish |
| , | Website down Sep 2021 - Feb 2022 | |
| , | Website down Apr 2024 - Aug 2024 | |
| , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 | |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Science 37 | Culver City, CA | CRO Recruitment |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| Noble | Orlando, FL | Auto-injector Trainers |
| , | Merged with Bioreclamation and became BioreclamationIVT | |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 | |
| , | Bought by Lake Region Medical, Aug 2009 | |
| , | Assets acquired by Visus Therapeutics, Sep 2022 | |
| , | Bought by Stryker, Oct 2019, $500M | |
| , | Bought by Boston Scientific, Sep 2010, $194M + milestones | |
| , | Renamed selectION Therapeutics | |
| , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 | |
| , | Acquired by BioNTech, May 2020, $67M | |
| , | ||
| , | No info Aug 2021 - May 2023 | |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| , | Renamed Evexta Bio, Nov 2023 | |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| , | Renamed Parabilis Medicines, Oct 2024 | |
| Kelliop | Newark, CA | Diagnostic Reader |
| , | Acquired by Cerecor, Nov 2017 | |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 | |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| |
Kaiseraugst, Switzerland | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Hera BioLabs | Lexington, KY | Toxicology CRO |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 | |
| Aseda Sciences | West Lafayette, IN | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| , | Merged with Transcriptic, to become Strateos, Jun 2019 | |
| Santen | Emeryville, CA | Ophthalmics |
| , | Website down Feb 2021 | |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| , | Renamed AblaCor, Jan 2013 | |
| Experimentica | Fort Worth, TX | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| ChemAxon | Budapest, Hungary | Cheminformatics software platforms |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Website from 2013 as of Dec 2020 | |
| , | Acquired by Tome Biosciences, Jan 2024, $185M | |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| , | Seems gone, Nov 2022 | |
| , | Merged with ReCode Therapeutics, Mar 2020 | |
| , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct | |
| , | Website Gone, Mar 2017 | |
| |
Hesperia, CA | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| WhiteLab Genomics | Evry, France | Cell & Gene Therapy Services |
| , | Ostensibly Gone after failed trial, Nov 2013 | |
| , | ||
| , | Renamed Liom, Jul 2024 | |
| , | Apparently renamed Elios Therapeutics | |
| Flash Biosolutions | Toulouse, France | Gene Delivery, Services |
| , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones | |
| , | Acquired by Hitachi Medical, Jun 2011 | |
| , | Bought by Accuray, Mar 2011, $277M | |
| , | Rebranded as AbVacc | |
| , | Acquired by Hi-Tech Pharmacal, Dec 2007 | |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 | |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| , | Merged with Horizon Pharma | |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| , | Website down May 2023 - Dec 2023 | |
| Baxter | Singapore, Singapore | Medication Delivery |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| LadRx | Los Angeles, CA | Small Molecules, DNA |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Distributor | |
| , | Merged into Endo, Jul 2000 | |
| , | Acquired by Regeneron, May 2022, $250M | |
| Eisai | Nutley , NJ | Small Molecules |
| , | Acquired by Chiltern, Jul 2014 | |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| , | Website down Oct 2021 - Mar 2022 | |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| , | Dissolved, Jun 2021; fka 4s3 Bioscience | |
| , | Changed name to Avanir Pharmaceuticals, 1998 | |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Renamed Ryght, Nov 2023 | |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| , | Shut down Oct 2024 | |
| |
San Jose, CA | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Acquired by Bio-Techne, 2011 | |
| , | Bought by Amgen, Jan 2011, $425M + $575M milestones | |
| NeurOptics | Irvine, CA | Pupillometry |
| , | Renamed PYC Therapeutics, 2019 | |
| Thermo Fisher | Bend, OR | CDMO |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| , | Bankrupt, Apr 2021 | |
| , | Now Kbio | |
| , | Acquired by Integrated DNA Technologies, Mar 2021 | |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| , | Renamed Kidswell Bio | |
| , | Website down Jan 2019-Feb 2019 | |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| , | Website down Jul 2022 - Nov 2022 | |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| , | Acquired by IMA Group, Oct 2021 | |
| , | Now BionX Medical | |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| , | Small time, no info. Defunct | |
| , | Acquired by Chiesi Farmaceutici, Feb 2014 | |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Neuroservices-Alliance | Aix-en-Provence, France | Translational Data Contract Work |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza | |
| Zyagen | San Diego, CA | Life Science Reagents |
| Nutcracker Therapeutics | Emeryville, CA | mRNA manufacturing device |
| , | Gone by 2023; aka Immunomolecular Therapeutics | |
| Benchmark Research | Fort Worth, TX | Clinical Research |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| Abcam | Waltham, MA | Antibodies |
| , | Acquired by UCB Pharma, Jun 2017 | |
| , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 | |
| , | Gone 2019-2020 | |
| Taros Chemicals | Bangalore, India | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Refeyn | Oxford , UK | Mass Photometry |
| , | Merged with Valeant | |
| , | Website down Oct 2022 - Feb 2023 | |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| , | Merged with Synlogic, Aug 2017 | |
| , | Website down Feb 2024 - Dec 2024 | |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| , | Acquired by MBL International, 2008 | |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now | |
| , | Acquired by Takeda, Feb 2005, $270M | |
| , | New Dec 2016, no site Aug 2018 | |
| , | Website hijacked, delayed redirect Apr 2023, not registered in MA | |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| , | Personnel on website is outdated. No one LinkedIN works there | |
| Oncternal Therapeutics | San Diego, CA | Oncology antibody treatments |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| , | Acquired by Sartorius, Aug 2021, €50M | |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| , | Acquired by GE Apr 2012 | |
| , | Gone | |
| , | Acquired by WIRB-Copernicus Group, Jul 2014 | |
| Novozymes | Beijing, China | Enzymes |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| , | Now Genprex | |
| , | Acquired by Cephalon Mar 2011 | |
| , | Acquired by Schott, Sep 2021 | |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| , | Home page taken over by scammy reveiws | |
| , | Website weird Dec 2023 - Jul 2024 | |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| , | ||
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| |
Utrecht, Netherlands | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| , | Filed Chapter 11 Bankruptcy, Feb 2019 | |
| , | Antibody Platform sold between 2011-2014 | |
| , | Renamed Depixus | |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| , | Renamed Visterra Inc in May 2010 | |
| , | Acquired by Thermo Fisher, Jan 2022, $1.85B | |
| , | Renamed EXACT Therapeutics | |
| Innovagen | Lund, Sweden | Custom antibody development |
| , | Acquired by Bausch + Lomb, Jan 2025 | |
| , | Gone May 2019 | |
| , | Acquired by Pacira BioSciences, Nov 2021 | |
| , | Shut down Dec 2024 | |
| Genetron Health | Beijing, China | Diagnostics |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 | |
| , | Website gone, May 2015 | |
| , | Acquired by Innovia Medical, Nov 202 | |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| , | Bankrupt Jun 2013 | |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| , | Website down Jan 2021 - May 2021 | |
| , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 | |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| , | ||
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| , | ||
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| , | Don’t believe this company is active; website from 2006 as of Dec 2019 | |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| , | sold by Galapagos to Selvita, Nov 2020, $37M | |
| Vrata Therapeutics | Cambridge, | |
| , | Now Aptiv Solutions | |
| , | Bankrupt | |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| , | Closed 2013 | |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| , | Renamed TALi Digital | |
| , | Acquired by FSD Pharma, Jun 2019 | |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| , | Merged with Obtala Sciences, became Talara Antibodies | |
| , | Website Gone, no response from employees | |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| TumorGen | San Diego, CA | Cancer Treatments |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| , | No website, no info Jan 2019 - May 2023 | |
| , | ||
| Liminal Sciences | Guilford, CT | Noninvasive Measurement of Brain Vitals |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| , | Website gone, Feb 2015 | |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| , | Acquired by Certara, Dec 2023 | |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| , | Acquired by Watson Pharmaceuticals, Feb 1997 | |
| , | Not registered in CA, website gone Jan 2018 | |
| , | Gone, taken down by SEC for scammy behavior | |
| , | Renamed Geneious | |
| , | ||
| Provisio Medical | San Diego, CA | Endovascular Devices |
| , | Liquidated May 2016 | |
| , | Doesn't seem active, Jul 2018 | |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| Laborie | Portsmouth, NH | Medical Devices |
| , | Gone | |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| , | Now PDx Biotech | |
| , | Acquired by Ligand Jan 2011 | |
| , | ||
| , | No business filings Jan 2022 - Aug 2024 | |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| , | Website gone Jan 2021 | |
| , | Older name for Argenx | |
| Lannett | Trevose, PA | Generic Small Molecules |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| Innovacell | Innsbruck, Austria | Cell Therapy Incontinence Treatments |
| , | ||
| , | Website Gone, Apr 2016 | |
| , | Website expired Nov 2019 - Feb 2020 | |
| , | ||
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| Getinge | Delft, Netherlands | Medical Technology |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Aerovate Therapeutics | Waltham, MA | Inhaled Version of Imatinib |
| , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 | |
| , | Acquired by Infinity Laboratories, Jun 2020 | |
| , | Merged with Cambridge Major Labs, renamed Alcami | |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| AOP Orphan Diseases | Kista , Sweden | Orphan disease treatments |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| , | Website down Aug 2022 - Feb 2023 | |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| , | Gone | |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| GSK | Irvine, UK | Small Molecules, Vaccines, Biologics |
| , | Renamed Prescient Therapeutics, Dec 2014 | |
| , | ||
| , | Renamed ProSciento | |
| , | Merged into Proterris, May 2017 | |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| , | ||
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| , | Acquired by PerkinElmer, Jun 2021 | |
| Ultimate Medicine | , | Dementia Medicines |
| , | Renamed BlueWillow Biologics, May 2018 | |
| , | Website Gone | |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 | |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Cary Pharmaceuticals | Great Falls, VA | Small Molecules |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| , | Bought by Intrexon, Aug 2015, $160M | |
| , | Merged with Cyberonics, renamed LivaNova, Oct 2015 | |
| , | Merged with Celltech, Jun 1999 | |
| FivePharma | Kilkenny, Leinster | Quality Consulting |
| AMS Biotechnology | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Hepalink | Shenzhen, China | Heparin API |
| , | Renamed MicroGEM | |
| , | Changed name to Ocata Therapeutics, Nov 2014 | |
| , | Website down Dec 2022 - Apr 2023 | |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| , | Acquired by Recordati, May 2016 | |
| , | Assets sold by parent company, Aug 2012 | |
| , | Acquired by PerkinElmer, 2010 | |
| CO.DON | Leipzig, Germany | Cell Therapies |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| , | Became Zycos | |
| , | Assets bought by MedCision, May 2018 | |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Acquired by LTS, Aug 2022 | |
| , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 | |
| HanchorBio | Taipei City, Taiwan | Fc-Based Designer Biologics |
| , | Renamed Samabriva | |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| Stada | Bad Vilbel, Germany | Generics |
| Ginolis | San Diego, CA | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| InnoVoyce | Boston, MA | ENT Lasers |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| , | Website down Oct 2021 - Feb 2022 | |
| , | Shut down, Nov 2016 | |
| , | Renamed Aptalis after acquiring Eurand, May 2011 | |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| , | Gone | |
| , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 | |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| , | Dissolved Jun 2021 | |
| , | Website down Jul 2024 - Dec 2024 | |
| , | ||
| , | Filed Chapter 11 bankruptcy, Sep 2019 | |
| , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 | |
| , | Website under construction, Aug 2020 - May 2021; GSK spinout | |
| , | Acquired by Velocity Clinical, Dec 2020 | |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| , | Gone | |
| PARI Pharma | Gräfelfing, Germany | Nebulizer Product Development Services |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| , | No website, Dec 2018 - May 2023 | |
| , | Folded into Muna Therapeutics, Jul 2021 | |
| , | Acquired by BMS, Mar 2024, $12.7B | |
| , | Acquired by SGS, May 2012 | |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Website down Jun 2023 - Dec 2023 | |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| , | ||
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| , | Website gone Jan 2019 | |
| , | Website down Jan 2024 - Jul 2024 | |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| Basilard BioTech | , CA | Gene Delivery Platform |
| , | Rebranded as Ikena Oncology, Dec 2019 | |
| , | Run by a lab tech out of his house, no product info on website | |
| Gilson | Middleton, WI | Lab Supplies |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| , | Acquired by Medtronic, Sep 2022, $1B | |
| , | Shut down Jul 2023 | |
| , | Renamed Level Bio, May 2024 | |
| , | Acquired by Lilly, Jan 2017, $960M | |
| , | Gone 2017 | |
| , | Renamed Camena Bioscience, Sep 2017 | |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| , | ||
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| , | Renamed NeuraSignal, Jan 2024 | |
| , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 | |
| , | Renamed Quotient Sciences, Nov 2017 | |
| Pion | Billerica, MA | Dissolution Data |
| , | Shut down Dec 2024 | |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| , | Acquired by Harbour Biomed, Dec 2016 | |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Gameto | New York, NY | Female Fertility Extension |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| EuroAPI | Paris, France | API Production, CDMO |
| , | Acquired by Merck, Nov 2009 | |
| , | Renamed AeenaDx, May 2022 | |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| , | Renamed FMI holdings, got out of drug business | |
| Accellacare | Downers Grove, IL | Clinical Research |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| , | Website down Oct 2021 - Jul 2022 | |
| Diag-Nose.io | Melbourne, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| , | Website gone Nov-Dec 2017 | |
| |
Philadelphia, PA | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Shut down Nov 2022 | |
| Galapagos | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Diffuse Bio | Menlo Park, CA | Generative AI for Protein Design |
| , | ||
| , | Business filings late May 2023 - Feb 2025 | |
| , | Renamed Neuphoria Therapeutics, Dec 2024 | |
| , | Acquired by AZTherapies, Oct 2019 | |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| Belenos Biosciences | New York, NY | Antibody Therapies |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| , | No news 2017-2024, Employees all gone Jul 2024 | |
| , | Renamed Bonti, Aug 2015 | |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| , | Shut down for fraud 2003, unapproved stem cell treatments | |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| Caidya | Shanghai, China | Clinical Research Organization |
| , | Shut Down Nov 2023 | |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| , | Merged into Melinta Therapeutics, Nov 2017 | |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| , | Folded into BridgeBio, Sep 2023 | |
| , | Purchased by NitricBio, Oct 2009 | |
| Nexus Spine | Draper, UT | Spinal Implants |
| , | Acquired by Teleflex, Jul 2012 | |
| , | Acquired by Asahi Kasei Pharma, Nov 2011 | |
| , | Renamed TD2 Precision Oncology | |
| Alera Labs | Durham, NC | Contract Research & Services |
| , | Acquired by Recipharm, Apr 2022 | |
| Iterum Therapeutics | Chicago, IL | Anti-infectives |
| , | ||
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| , | ||
| , | ||
| , | Shut down Feb 2020 | |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| Fortrea | Durham, NC | Clinical Research |
| , | Website gone Oct 2019; Assets seem to have moved to Angion | |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| , | Renamed Precirix, Sep 2020 | |
| , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones | |
| , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 | |
| Adovate | Charlottesville, VA | Adenosine Compounds |
| , | Predecessor of NeXus Therapeutics | |
| AtriCure | Mason, OH | Cardiovascular Devices |
| Sage Therapeutics | Cambridge, MA | Small Molecules for CNS Disorders |
| , | Now Asante Solutions | |
| , | LI page gone Nov 2023, no info on website 2020-2024 | |
| , | Website gone Mar 2019 | |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| , | ||
| , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. | |
| , | Founders both gone Feb 2021 | |
| , | Acquired by Genesis Biotechnology Group, Jun 2019 | |
| , | Bought by BMS Aug 2012 | |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Apollomics | Xiaoshan, China | Cancer medicines |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| Neurosoft Biolelectronics | Geneva, Switzerland | Metal Films for Implants |
| restor3d | Durham, NC | 3D printed implants and devices |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| , | Acquired by Aptuit, Apr 2016 | |
| , | Closed | |
| , | ||
| Acumed | Hillsboro, OR | Medical Implants |
| , | Liquidated Dec 2019 | |
| PolarityTE | Salt Lake City, UT | Cell Regeneration Technology |
| , | No news 2016 - Aug 2024 | |
| , | Bought by Neogen, Jan 2013 | |
| , | Website Gone, Sep 2017 | |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| , | ||
| , | Acquired by CTI Facts, Sep 2020 | |
| , | Website down May 2020 - Aug 2020, taken over Sep 2020 | |
| AniLocus | Germantown, MD | Preclinical CRO |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| , | Bought by 10X Genomics, Oct 2020 | |
| , | Website down, Founder gone Mar 2021 | |
| , | Acquired/Merged with Edesa Biotech, Jun 2019 | |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now | |
| Endo Pharmaceuticals | Dublin, Ireland | Small Molecules |
| , | Website down, owners/founders have other jobs | |
| Turku Bioscience | Turku, Finland | Research Services |
| , | ||
| , | Closed per Google | |
| , | Merged with Deep Origin, Jan 2024 | |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| , | Folded into Expedeon, Mar 2018 | |
| , | Bought by Beckman-Coulter, Oct 2006 | |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| , | Gone | |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Amador Bioscience | Ann Arbor, MI | Consulting, Lab Service, Clinical Trial Management |
| , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 | |
| Agilent | Folsom, CA | High-Throughput Screening Equipment, Imaging instruments |
| Alimera Sciences | Alpharetta, GA | Small Molecules |
| , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 | |
| Entero Therapeutics | Boca Raton, FL | Oxidative Phosphorylation Disruption Therapies for IBD |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| , | Seems to be rolled into Norgine after started as a JV | |
| T-Cypher Bio | Oxford, UK | TCR-based Therapeutics |
| , | Shut down Jul 2024 | |
| , | Renamed Outlook Therapeutics, Dec 2018 | |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| , | Renamed ERBA Diagnostics, Jun 2012 | |
| , | ||
| Ergomed | Surrey, UK | Clinical Research |
| , | Acquired by Stryker, Oct 2018, $190M | |
| , | Renamed Mitobridge | |
| , | Shutting down Jan 2019 after Medicare stopped covering product | |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria | |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| Ascend Advanced Therapies | London, UK | Gene Therapy CDMO |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| , | Website down Feb 2022 - Jul 2022 | |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Quintara Discovery | Hayward, CA | In vitro ADME profiling, bioanalysis services, and dedicated assay development and compound screening |
| , | Acquired by Adamis, Feb 2008 | |
| Aerin Medical | Austin, TX | Nasal Obstruction Relief Device |
| , | Now part of AGC Biologics | |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| , | Renamed Velocity Clinical Research | |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| , | Gone Jun 2017 | |
| , | Acquired by St. Jude Medical, Jun 2015, $455M | |
| Tanvex BioPharma | Irvine, CA | Biologics Services, CDMO |
| , | Shut down Feb 2019 | |
| , | Website down Jan 2020 - Sep 2020 | |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| , | Gone, site still up | |
| Medtronic | Santa Rosa, CA | Medical Devices |
| , | Acquired by Merge eFilm, Jan 2005 | |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 | |
| , | Renamed Orphalan | |
| , | ||
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| , | ||
| , | Website down May 2021 - Sep 2021 | |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| , | Website down May 2023 - Dec 2023 | |
| ChomiX Biotech | Nanjing, China | Small Molecule Proteomics |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Innovaderm | Montréal, QC | Dermatology Clinical Research |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Science 37 | Durham, NC | CRO Recruitment |
| , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 | |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| , | Phantom company | |
| , | Website down Dec 2022; Majority-owned by Aethlon Medical | |
| Zai Lab | Beijing, China | Small Molecules |
| , | Acquired by Bachem, Feb 2015 | |
| , | Website gone, Mar 2019 | |
| , | Renamed BrightPath Biotherapeutics, Jul 2017 | |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| , | Gone | |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| , | ||
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| , | Acquired by Cardinal Health, May 2007, $1.5B | |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Curadev | Noida, India | Immuno-oncology |
| , | Bought by Forest Labs Feb 2011 | |
| Pharmaron | Tianjin, China | R&D Services |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| , | No news 2014 - Jul 2024; Residential Address Aug 2022 | |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| , | Gone | |
| , | Acquired by Access Pharmaceuticals, Feb 2009 | |
| , | Acquired by GE Healthcare, May 2012 | |
| , | Technology bought by Roche Diagnostics, Dec 2014 | |
| Alcon | Mississauga, ON | Eye Care Products |
| , | Acquired by Arecor Therapeutics, Aug 2022 | |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| Medtronic | Jacksonville, FL | Medical Devices |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| , | ||
| Asceneuron | Lausanne, Switzerland | Tauopathies and Alzheimer’s disease |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| , | Bought by DuPont | |
| Spexis | Allschwil, Switzerland | Macrocycles', which are between small and large molecules |
| , | Bought by Ultragenyx, Nov 2017 | |
| , | Gone Jun 2018 | |
| LEUCID BIO | London, UK | Cell Therapy |
| , | Gone, late 2017 | |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| |
Feldkirchen, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| Averoa | Meylan, France | Iron-based Compound |
| , | Gone Aug 2017 | |
| , | Bought by Boston Scientific, Jul 2016 | |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| , | Website down Sep 2021 - Jan 2022 | |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| , | Website down May 2021 - Feb 2022 | |
| IO Biotech | Copenhagen, Denmark | Immuno-Oncology |
| Eli Lilly | Cambridge, MA | Small Molecules, Biologics |
| , | 10 years, no progress, no full-time employees | |
| , | ||
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| , | Now part of Tigermed | |
| , | Merged into Leap Therapeutics | |
| , | Website down Sep 2023 - Mar 2024 | |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| numares | Regensburg, Germany | Clinical Diagnostics |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| ICU Medical | San Clemente, CA | Disposable medical products |
| Inventprise | Redmond, WA | Vaccines |
| , | Acquired by Precision for Medicine, Jul 2019 | |
| , | Renamed Aug Bioservices, Jul 2020 | |
| Capzer Pharmaceuticals | Lake Worth, FL | GC, HPLC Services |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| , | Changed name to ReNetX Bio, Jul 2017 | |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| , | Shut down Jan 2021 | |
| , | Website down Nov 2023 - Mar 2024 | |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| , | Acquired by Keryx Biopharmaceuticals, Jan 2004 | |
| , | Not a registered business, Feb 2025 | |
| , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 | |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| , | Website down Apr 2024 - Aug 2024 | |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| , | Website down Dec 2022 - Apr 2023 | |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| , | Website down Mar 2020 - Jan 2021; fka Illumicure | |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| , | Changed name to Atterx Biotherapeutics late 2014/early 2015 | |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| , | Shut down Jun 2021 | |
| OncoOne | Klosterneuburg , Austria | Cancer Drug Discovery |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| Spark Therapeutics | Philadelphia, PA | Singe Dose Gene Therapy |
| MGB Biopharma | Bellshill, UK | Small Molecule Antibacterial |
| , | Website gone Jun 2019 | |
| , | Acquired by GSK, Feb 2025 | |
| , | Website down Dec 2023 - May 2024 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Next generation T-cell receptor mimic (TCRm) antibody | |
| , | Acquired by Quintiles, Jun 2017 | |
| Neuro3 Therapeutics | , | |
| Pace Analytical | Minneapolis, MN | Analytical Testing |
| , | Website down Sep 2022 - Feb 2023 | |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| , | Acquired by Biota, Feb 2015 | |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 | |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| , | Assets sold 2005 | |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| , | Closed | |
| , | Failed Phase 3 Mar 2020, website gone Jan 2021 | |
| , | Website down Jan 2024 - Aug 2024 | |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| , | Acquired by Sandoz, Jun 2005 | |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| Celerion | Belfast, UK | Clinical Research |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 | |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| , | Bought by AstraZeneca, May 2013, $323M | |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| , | Now AAIPharma | |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| , | Effectively defunct late 2003 | |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| , | ||
| , | Acquired by Agenus, Feb 2022 | |
| Cellesce | Cardiff, UK | Organoid biobank for R&D, contract bioprocessing |
| , | Shut down 2019 | |
| , | ||
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| , | Main guy left for big company, website down Mar 2020 | |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| , | Acquired by Twist Biosciences, Jun 2021 | |
| Celerion | Tempe, AZ | Clinical Research |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| , | Website down Feb 2023 - Jul 2023 | |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 | |
| , | Changed name to Freudenberg Medical, Aug 2015 | |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Nipro Medical | Bridgewater , NJ | Dialyzer, Guidewires, Needles, Syringes, etc |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| , | Acquired by AbbVie, May 2024, $137.5M | |
| , | Merged with GTX Medical, Oct 2019 | |
| , | Shut down Sep 2023 | |
| Vetter | Ravensburg, Germany | Aseptic Filling |
| , | Acquired by CardioNet, 2010 | |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| , | ||
| , | Acquired by Ariceum Therapeutics, Jun 2023 | |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| , | Acquired by OnCore Biopharma Oct 2014 | |
| , | Acquired by Agenus, Dec 2015, up to $45M | |
| , | ||
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Actome | Freiburg im Breisgau, Germany | Protein Quantification |
| , | Renamed Pacgen Life Science Corp. | |
| Charles River Laboratories | Horsham, PA | Research Animal Models and Preclinical Research |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| DropGenie | Cambridge, MA | Automated Gene Editing |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Acquired by Quintiles, Sep 2013 | |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| , | ||
| , | Renamed Refractal | |
| , | Renamed Axoltis Pharma | |
| , | Shut down Nov 2020 | |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| BioSig Technologies | Westport, CT | Biomedical Signal Processing |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| , | Bankrupt May 2011 | |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| , | Shut down Jul 2021 | |
| Novozymes | Bagsvaerd, Denmark | Enzymes |
| Smart Immune | Paris, France | Thymus-empowered T-cell Therapy |
| , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 | |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| Covis Pharma | Zug, Switzerland | Specialty Pharmaceuticals |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| , | Acquired by Celtic Pharma | |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| MedinCell | Jacou, France | API Delivery Gel |
| Padagis | Allegan, MI | Generics |
| , | Website down Jul 2022 - Nov 2022 | |
| Senzime | Uppsala, Sweden | Devices |
| , | Now Acellacare | |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| , | No info, website gone, presumed gone | |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| , | Acquired by BTG plc, Oct 2017 | |
| , | Acquired by Invitae, Mar 2020 | |
| , | Renamed Starton Therapeutics, Dec 2019 | |
| , | Acquired by Amtech Systems, 2023 | |
| , | Presumed gone | |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| , | Acquired by BD, Aug 2015 | |
| , | Renamed Anagram Therapeutics, Apr 2023 | |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| , | ||
| , | Founder gone Oct 2021, no employees | |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida | |
| Asensus Surgical | Durham, NC | Robot surgical system |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| AB ANALITICA | Padua, Italy | Sequencing products |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| , | Acquired by bioMérieux, Apr 2018, $90M | |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV | |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| , | Website Gone, Nov 2016 | |
| ConfometRx | Santa Clara, CA | Structure-based drug development tools |
| , | Merged with NemaMetrix, Nov 2017 | |
| , | Gone May 2021 | |
| , | Funded in 2011, no website in Aug 2021 | |
| , | ||
| , | Shut down Jul 2024; fka Dance Biopharm | |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals | |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Integer | El Paso, TX | Medical & Surgical Devices |
| , | Rebranded as Coegin Pharma | |
| , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M | |
| Vicebio | London, UK | Molecular Clamp technology platform for vaccines against life-threatening respiratory viral infections |
| Crown Bioscience | Beijing, China | Drug Development |
| , | Acquired by Eligo Health Research, Jan 2019 | |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| , | ||
| Trinity Biotech | Bray, Ireland | Diagnostics |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| , | Renamed AustinPx, Sep 2022 | |
| , | Website down Apr 2024 - Sep 2024 | |
| Novo Nordisk | Athlone, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Plexision | Pittsburgh, PA | Diagnostics |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| , | Acquired by Teva, May 2011 | |
| , | Renamed ATON Group | |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| , | Now part of Oxford Biomedica | |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| , | Bankrupt 2009 | |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Azurity Pharmaceuticals | Wilmington, MA | Compounding Kits |
| EMS | Hortolândia, Brazil | Small Molecules |
| , | Renamed HemaFlo Therapeutics, Jan 2016 | |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Fountain Therapeutics | South SF, CA | AI-based drug screening platform for age-related therapies |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 | |
| , | ||
| , | Renamed ChironWells | |
| Ipsen | Signes, France | Small Molecules, Biologics |
| , | New owner/name, Jul 2016, per former CEO | |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Vericel | Ann Arbor, MI | Cellular Products |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| , | Employees all gone, Jul 2024 | |
| Mitsubishi Tanabe Pharma | Jersey City, NJ | Small Molecules |
| , | No website, no info Oct 2022 - May 2022 | |
| , | bankrupt? | |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 | |
| , | Acquired by Frontage, Dec 2019 | |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| , | ||
| Altasciences | Overland Park, KS | Contract Research |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| , | Merged with Neurimmune | |
| , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 | |
| , | Acquired by Olon, Jan 2019 | |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| , | Gone 2021 | |
| , | ||
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| , | ||
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| , | Website taken over Jul 2021 | |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| , | Reverse merged with Kineta, Dec 2022 | |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| , | Acquired by Abbott, Sep 2015, $225M | |
| , | Website down Dec 2021 - Apr 2022 | |
| , | Acquired by Medtronic, Jul 2015, $110M | |
| , | Acquired by Hologic, May 2007, $6.2B | |
| , | Website down Feb 2022 - Jun 2022 | |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| hC Bioscience | Boston, MA | tRNA-based Therapeutics |
| , | Acquired by Optima Pharm, Jun 2022 | |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| , | Changed name to CASI Pharmaceuticals, Jun 2014 | |
| Alkermes | Waltham, MA | Small Molecules |
| , | Website down Sep 2021 - Feb 2022 | |
| , | ||
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| , | Website gone Jul 2015 | |
| Viva Biotech | Shanghai , China | Contract Research |
| , | Renamed Merit CRO, Apr 2021 | |
| , | Renamed ArcticZymes, Jun 2020 | |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| , | Acquired by Oncocyte, Feb 2020 | |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| , | Acquired by Masimo, Mar 2020 | |
| , | Acquired by BioMarin Pharmaceuticals, 2010 | |
| , | Website gone Aug 2018, no response from CEO, presumed defunct | |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| Rubicon Research | Thane , India | Generics |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Rila Therapeutics | San Francisco, CA | Renal fibrosis treatments |
| , | Merged into Qualigen, May 2020, took its name | |
| , | Website down Jul 2021 - Dec 2021 | |
| TG ImmunoPharma | Hefei, China | Bispecific Antibody |
| , | Renamed Praxis Precision Medicines, Oct 2016 | |
| , | Website down May 2020; Not registered in CA Dec 2019 | |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Securecell | Urdorf, Switzerland | Lab automation |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| , | Sold in 2003 | |
| Rhaeos | Evanston, IL | Shunt Monitor |
| , | Website down Mar 2022 - Oct 2022 | |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| , | Renamed Ogeda Oct 2016 | |
| , | Website down 2020 - 2024 | |
| Medtronic | Dublin, Ireland | Medical Devices |
| , | Acquired by Kimball Electronics, Jul 2016 | |
| , | Merged with Ocuphire Pharma, Nov 2020 | |
| , | Acquired by BioDelivery Sciences, Aug 2004 | |
| , | Shut down Sep 2023; fka LuinaBio | |
| , | Website down Oct 2022 - Apr 2023 | |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Stada | Bad Vilbel, Germany | Generics |
| , | Acquired by Quidel, Nov 2013, $130M | |
| , | ||
| iotaSciences | Oxford, UK | Single-Cell Handling |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| , | Acquired by Meda, Aug 2013 | |
| , | ||
| , | Acquired by Aprea Therapeutics, May 2022 | |
| , | ||
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| iBio | Bryan, TX | Antibody Therapies |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems | |
| , | Website down Apr 2024 - Sep 2024 | |
| , | Acquired by Charles River, Jan 2023, $40M | |
| HealPros | Atlanta, GA | Diabetic retinopathy diagnosis |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Kallyope | New York, NY | Gut-brain axis focus |
| , | Renamed Sevion Therapeutics, Sep 2014 | |
| , | Renamed NUsurface | |
| , | Acquired by Penumbra, Sep 2018 | |
| , | Acquired by Roche 2011 | |
| Faraday Pharmaceuticals | Seattle, WA | Elemental reducing agents |
| , | Renamed iovera | |
| , | Late business filings Aug 2021 | |
| , | Acquired by ConMed, Jan 2016, $265M | |
| , | Website down Jul 2021 - Sep 2021 | |
| , | Bought by MedImmune, Apr 2013 | |
| , | Gone | |
| , | ||
| , | Acquired by Allergan, Oct 2015, $300M | |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| , | Acquired by Charles River, Jan 2021, $83M + $21M milestones | |
| , | Website gone May 2023 | |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| , | Renamed Xilio Therapeutics, Mar 2020 | |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Univercells | Charleroi, Belgium | Affordable biologics / advising |
| , | Acquired by Zimmer Biomet, Aug 2024 | |
| , | Website gone Jan 2020 | |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| , | Renamed SciSparc, Jan 2021 | |
| , | Renamed WaveBreak, Apr 2023 | |
| , | Website down Aug 2024 - Feb 2025 | |
| , | Doesn't seem active, Mar 2024 | |
| Arcellx | Rockville, MD | Adaptive Immune Cell Therapies |
| , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 | |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| , | Liquidating Jul 2024 | |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| , | No website Aug 2022 | |
| , | Renamed SOL Global, Oct 2018 | |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| , | Renamed Luzsana, May 2022 | |
| , | Doesn't seem active Aug 2022 | |
| , | Bought by Pfizer 2006 | |
| , | Website down Dec 2017-Mar 2018 | |
| , | Website down Jun 2024 - Nov 2024 | |
| , | Acquired by BioIVT, Jul 2021 | |
| , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma | |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Rancho Biosciences | San Diego, CA | Curation of Health and Research Data |
| , | InVivoScribe Subsidiary. Integrated as of Apr 2015 | |
| , | Website gone Jan 2020, no info | |
| , | Now Beckman Coulter Genomics | |
| , | Seems gone after being sold back to founder | |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Mydecine Innovations | Vancouver, BC | Small Molecules |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| , | Acquired by Quotient Clinical, Feb 2017 | |
| , | Website taken over, company presumed gone | |
| Jubilant Therapeutics | Bedminster, NJ | Small Molecules |
| , | Website down Sep 2024 - Feb 2025 | |
| , | Acquired by Valeant Oct 2011 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Website Gone | |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Accipiter Biosciences | Seattle, | |
| , | Shut down before Nov 2023 | |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| , | Acquired by Cyclacel, Oct 2007 | |
| , | Acquired by HiFiBiO, Oct 2018 | |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| PuREC | Tokyo, Japan | Regenerative cell therapy using purified Mesenchymal Stem Cells |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Mural Oncology | Waltham, MA | Immunotherapies |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| , | Merged with Akari Therapeutics, Nov 2024 | |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| , | Now Silence Therapeutics | |
| PeriGen | Cary, NC | Perinatal Devices |
| , | Changed name to Denovo Biopharm | |
| , | Gone 2018 | |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| , | Gone, Jun 2013 | |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| , | Website states closed down; Website down Apr 2023 - Jun 2023 | |
| Hunterian Medicine | Cambridge, MA | CRISPR-based drug discovery |
| , | Website down Dec 2021 - Jul 2022 | |
| , | Bought by Teva, Jan 2014, $144M | |
| , | Shut Down Jul 2019 | |
| , | Website gone, Oct 2015 | |
| , | Bought by Valeant Pharmaceuticals Dec 2012 | |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| , | Bought by Gilead Dec 2012 | |
| , | Gone | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Acquired by Inotiv, Oct 2021, $15M | |
| , | Bought by Boston Scientific, Apr 2018, $40M | |
| , | Acquired by Biosense Webster, Nov 2015 | |
| , | Acquired by BioIVT, Jul 2018 | |
| BC Technical | West Jordan, UT | Imaging |
| , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 | |
| , | Renamed Coherus Biosciences, Apr 2012 | |
| , | Rebranded as Akrevia Therapeutics | |
| , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences | |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| , | Website down Jun 2021 - Oct 2021 | |
| , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones | |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| Vanessa Biotech | Farmington, CT | Treatments for underserved populations |
| , | Website down Apr 2023 - Sep 2023 | |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| , | Renamed Randstadt Pharma | |
| Ovation.io | Portland, ME | LIMS |
| , | Acquired by Affymetrix, Nov 2011, $330M | |
| , | Merged into Marker Therapeutics, Oct 2018 | |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| ViferaXS | Tübingen, Germany | Immunopeptidome-based antigen |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| Catalyst Clinical Research | Schiphol, Netherlands | Clinical research solutions to the global biopharmaceutical industry |
| Charles River Laboratories | Keel & Alderley park, UK | Dedicated plasmid DNA manufacturing facilities |
| , | Acquired by BioAgilytix, Feb 2016 | |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| , | Acquired by Elekta, Oct 2023 | |
| bioRASI | Aventura, FL | Clinical Research |
| , | ||
| , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma | |
| RootPath Genomics | Watertown, MA | Personalized T Cell Therapy Platform |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| Cellenion | Berlin, Germany | Single Cell Testing |
| , | Acquired by Grünenthal, Nov 2016 | |
| Mantra Bio | South SF, CA | Exosome Delivery |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| ReShape Lifesciences | Irvine, CA | Weight loss device |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| , | Website down Feb 2021 - Sep 2021 | |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| , | Changed name to Harbor Therapeutics | |
| , | ||
| Pfizer | Kalamazoo, MI | Manufacturing |
| , | Business filings 1.5 years late May 2024, no news since 2018 | |
| , | ||
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| , | Gone | |
| , | Acquired, Jan 2023 | |
| , | Renamed Tyrian Diagnostics, 2008 | |
| , | Changed name to Mast Therapeutics | |
| , | Liquidated | |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| , | Website down Jun 2024 - Nov 2024 | |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| , | Acquired by Lonza, Nov 2009 | |
| , | Renamed Zelegent, May 2015 | |
| , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics | |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| , | Seems gone Sep 2020 | |
| , | ||
| , | Website being updated Jun 2015-Dec 2019 | |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Texcell | Shanghai, China | Contract Research |
| , | No business filings, 2021-2024 | |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| LumiraDx | Waltham, MA | Diagnostic Platform |
| First Light Diagnostics | Chelmsford, MA | Benchtop Sample Analysis |
| , | Website gone Aug 2022 - Feb 2023 | |
| , | Part of Star Therapeutics | |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| , | Shut down May 2023 | |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Renamed Zevra Therapeutics, Feb 2023 | |
| , | Renamed Conavi Medical, Oct 2024 | |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| , | Bankrupt Sep 2007 | |
| , | Acquired by OpGen, Jul 2015 | |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| , | No info since 2010, Dates website, no Employees on LI | |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Gentell | Yardley, PA | Wound Care |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| , | Website gone Nov 2019 | |
| Muvon Therapeutics | Zürich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| , | Acquired by Nordic Pharma, Mar 2024 | |
| , | Gone Nov 2019 | |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | Renamed AlivaMab Biologics, Oct 2023 | |
| , | Chapter 7 Bankruptcy, June 2023 | |
| , | Website gone Jan 2019, Not updated since 2014 | |
| , | Product rights acquired | |
| Anoat Therapeutics | , | Antisense Oligonucleotides |
| Vevo Therapeutics | San Francisco, CA | in vivo single cell atlas |
| , | Website down May 2022 - Oct 2022 | |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| , | Website not working right, July-Oct 2014. No employees on LinkedIN | |
| , | Gone Nov 2018 | |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Octapharma | Lingolsheim, France | Plasma Products |
| , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded | |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| , | Merged with Vivalis to become Valneva May 2013 | |
| , | Bought by SuperGen, Apr 2006 | |
| Altasciences | Laval, QC | Contract Research |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| , | Website gone Jun 2024 - Aug 2024 | |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| , | Shut down Sep 2022 | |
| , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics | |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| , | Acquired by ICON plc., Jul 2021, $12B | |
| Emergent Biosolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| , | Acquired by NuChem Sciences, Aug 2021 | |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| , | Rebranded as Factor Therapeutics, Jan 2016 | |
| CureVac | Boston, MA | MRNA treatments |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| , | Bankrupt, 2017 | |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| , | Gone 2018 | |
| , | Acquired by Alere, Aug 2011 | |
| , | ||
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 | |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Ergomed | Cologne, Germany | Clinical Research |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| , | Website Gone | |
| , | Website gone May 2020 | |
| , | Renamed ILIAS Biologics | |
| Teva | Petach Tikva, Israel | Small Molecules, Biologics |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| SiliCycle | Québec, QC | Separation Technologies |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| , | Website down Oct 2022 - Mar 2023 | |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| Oncodesign Services | Montreal, QC | Preclinical services |
| , | ||
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| , | Founded 2004, GNT Pharma subsidiary | |
| , | Now Agilent | |
| , | Website Gone | |
| , | Website down Jan 2024 - Aug 2024 | |
| , | Acquired by Tesis Biosciences, Feb 2022 | |
| AstraZeneca | Coppell, TX | Small Molecules, Vaccines, Biologics |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| , | Website gone Dec 2022 | |
| , | Bankrupt | |
| , | No website Jan 2020 - Aug 2021 (founded 2001) | |
| , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 | |
| , | ||
| , | Acquired by Eli Lilly, Dec 2023, $1.4B | |
| , | Business Forfeited in MD, Nov 2008 | |
| , | Website down Apr 2024 - Aug 2024 | |
| , | Bought by Parexel, Jan 2016 | |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Benchmark Research | Austin, TX | Clinical Research |
| , | Website Gone May 2018 | |
| , | Renamed Oranomed, Jan 2018 | |
| , | Gone 2014 | |
| Organovo | San Diego, CA | Bioprinters |
| , | Acquired by Ximedica, Aug 2015 | |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Moleac | Singapore, Singapore | Stroke Products |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| LivaNova | London, UK | Nerve stimulation therapy |
| , | Seems inactive Aug 2022 | |
| , | Renamed Biosenic, Oct 2022 | |
| , | Acquired by Boston Scientific, Nov 2001, $150M | |
| IRBM | Pomezia, Italy | Drug discovery CRO / PRO |
| , | Gone 2015? | |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| , | Website down Mar 2023 - Dec 2023 | |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| , | ||
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| , | ||
| , | Exclusively licensed product to Processa Pharmaceuticals | |
| Pace Analytical | Asheville, NC | Analytical Testing |
| , | Became Constant Pharmaceuticals, Jan 2017 | |
| , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration | |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Gene Universal | Newark, DE | Gene Synthesis |
| , | Acquired by GeneCentric Therapeutics, Aug 2019 | |
| , | No business filings, Sep 2011 - Aug 2024 | |
| Advanz Pharma | London, UK | Specialty Generics |
| , | ||
| NeuClone | Sydney, Australia | Biosimilars |
| , | Gone 2021 | |
| , | Acquired by Bayer, Aug 2011, $125M | |
| , | Shut down 2015? | |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Syngene | Frederick, MD | Gel Imaging |
| , | Acquired by ScreenPoint Medical, Jan 2025 | |
| , | Website down Apr 2019 - Jun 2019 | |
| , | Bought by biotechne, Aug 2014, $300M | |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| , | Merged with Celsis IVT and became BioreclamtaionIVT | |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Medtronic | Mounds View, MN | Medical Devices |
| , | Wound Down, Jun 2013 | |
| , | Renamed Gene Biotherapeutics, became royalty company | |
| , | Merged with Rxi Pharmaceuticals | |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| , | Website down Feb 2024 - Sep 2024 | |
| Carisma Therapeutics | Philadelphia, PA | CAR Macrophage Immunotherapy |
| , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 | |
| Reset Pharmaceuticals | New York, NY | Psilocybin |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| , | Renamed Certified Testing, Jul 2023 | |
| , | Founded and owned by Arrowhead Research | |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| , | Gone 2016 | |
| , | Website down Aug 2023 - Feb 2024 | |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Physical Sciences | Andover, MA | Retinal Imaging |
| , | Acquired by Perkin Elmer, Mar 2021, $591M | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Acquired by Antigenics, Apr 2001 | |
| SoftGenetics | State College, PA | Software for genetic analysis |
| , | Acquired by ProGen, Feb 2008, $2.5M | |
| GenoSpace | Boston, MA | Platform for genomic data |
| , | Renamed Aelan Cell Technologies, Apr 2015 | |
| , | Website down Aug 2024 - Feb 2025 | |
| , | Website down Apr 2023 - Aug 2023 | |
| , | Renamed Parse Biosciences, Jan 2021 | |
| Atara Biotherapeutics | Zug, Switzerland | Peptibody, Monoclonal Antibody, Cell Therapy |
| , | Website down Jun 2021 - Dec 2021 | |
| , | Bought by NuVasive, Sep 2017 | |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Orion Genomics | St. Louis, MO | Biomarkers |
| , | Website taken over Mar 2020 | |
| , | Website down Jan 2021 - Mar 2021 | |
| , | Renamed Wake Clinical | |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos | |
| , | No website Dec 2019 - May 2023 | |
| Heraeus Medical | Concord, CA | Medical Devices |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| , | Shut down May 2023 | |
| , | Renamed CytexOrtho, Jun 2022 | |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| , | Centerwatch only | |
| , | Seems like a dead end joint venture | |
| , | Rolled in to Novan Therapeutics, Mar 2023 | |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| , | Chapter 11 Bankruptcy, Apr 2023 | |
| , | Renamed Velico Medical, Dec 2009 | |
| , | ||
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Bionoxx | Seongnam-si, Korea | Tumor-targeting Antigen |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| , | Website down Sep 2020 - Mar 2021 | |
| , | Acquired by Grunenthal Nov 2018 | |
| , | Acquired by Glaukos, Nov 2019 | |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| , | ||
| , | Acquired by Absci, Jul 2021 | |
| , | Acquired by EyeGate Pharmaceuticals, Jan 2021 | |
| , | ||
| , | Acquired by Recordati, Sep 2007 | |
| , | Acquired by Newron, Jun 2012 | |
| , | Gone by 2017, No info | |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| , | Website taken over by debt payment company | |
| CatSci | Cardiff, UK | Contract Research |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| , | Product didn’t work, pivoted | |
| , | Renamed Aspira Women's Health | |
| , | Owned by RepliCel Life Sciences | |
| , | Website down Jun 2024 - Dec 2024 | |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| , | Now OncoPlexDx | |
| , | Acquired by Velocity Clinical Research, Nov 2020 | |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| , | Acquired by MGI Pharma, Sep 2004 | |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| , | SEC troubles in 2008ish, gone | |
| , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 | |
| , | Business revoked in CA | |
| , | Acquired by GSK, Feb 2024, $1B + $400M milestones | |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| , | Renamed Aeolus Pharmaceuticals | |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| , | Renamed Skulpt Health | |
| , | Business filings years late, no employees on LI Jun 2022 | |
| , | Bought by Grifols? | |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Vista.ai | Palo Alto, CA | MRI Software |
| Aliada Therapeutics | Boston, MA | Antibody Therapy |
| , | Chapter 7 bankruptcy, Nov 2023 | |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| , | Acquired by Gilead, May 2023; Residential address Aug 2021 | |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| , | Website down Jul 2024 - Dec 2024 | |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| , | Website down Apr 2022 - Jul 2022 | |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| , | Website down Oct 2021 - Jul 2022 | |
| , | Acquired by QuartzBio, Jan 2023 | |
| , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering | |
| , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones | |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| , | ||
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| , | Seems folded into parent, Nov 2023 | |
| , | Bankrupt, Apr 2015 | |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| , | No website Dec 2020; Single-person company?, Dec 2019 | |
| Endologix | Irvine, CA | Medical Devices |
| , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 | |
| Sypharma | Victoria, Australia | Contract Small Molecule Manufacturing |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| , | Acquired by Nordic MUbio, Mar 2018 | |
| , | Gone late 2022 | |
| VitalScientific | , | Analytical Systems for Diagnostics |
| , | Website taken over May 2020 | |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Getinge | La Ciotat, France | Medical Technology |
| D2M Biotherapeutics | Natick, MA | Antibody Therapy |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| , | Website down Sep 2022 - Feb 2023 | |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| , | Renamed Bilhi Genetics, Mar 2018 | |
| , | Ancient website, presumed defunct | |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Biophytis | Paris, France | Therapies for aging diseases |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Lyra Therapeutics | Watertown, MA | Biomedical scaffold technology |
| , | Seems gone Dec 2020; Single-person company?, Dec 2019 | |
| , | Renamed Cymed Ostomy | |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 | |
| Agilent | Mechelen, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Metrohm | Pasadena, TX | Lab Data Management Software |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| , | Bought by HeartWare, Dec 2013, $30M+$320Milestones | |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 | |
| , | Acquired by Cancer Genetics, Aug 2017, $12M | |
| , | Acquired by Endo Oct 2014, $2.6B | |
| , | Acquired by ProStakan, Jul 2014, $394M | |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| , | Renamed Comet Therapeutics | |
| , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 | |
| Abbott | Irving, TX | Devices |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| , | ||
| , | Acquired by United Therapeutics, 2011, $7.6M | |
| , | Merged into Discovery Life Sciences, Oct 2018 | |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| , | Acquired by Illumina, Oct 2013 | |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones | |
| Epigene Labs | Paris, France | Data Integration Platform |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| , | Website gone Jul 2015-Feb 2016 | |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| , | ||
| , | ||
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Shut down, Jul 2015 | |
| , | Believe they are inactive | |
| , | Website down May 2023 - Dec 2023 | |
| Benchmark Research | Austin, TX | Clinical Research |
| , | Acquired by Viatris, Nov 2022 | |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| , | Website gone Mar 2023 | |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| , | Acquired by BMS 2008 | |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| , | Business revoked 2013, though they moved in 2015 | |
| STC Biologics | Newton, MA | Services |
| , | Seems like baloney company. SBIR | |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| , | Renamed Vesalius Therapeutics, Dec 2021 | |
| Furong Biotech | , | |
| , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 | |
| , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas | |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| , | Acquired by Pharmalex, Apr 2017 | |
| , | Website down Dec 2020 - May 2021; Spinout of EpiVax | |
| , | Bought by Cancer Genetics Jun 2014 ($6.5M) | |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| , | Closed, Dec 2016 | |
| , | Gone | |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| PanGIA Biotech | Delray Beach, FL | Liquid Biopsy |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| , | Acquired by Cephalon, 2010 | |
| , | Bought by bluebird bio Jun 2014 | |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| , | Gone | |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| Compugen | Holon, Israel | Biologics |
| AmplifyBio | West Jefferson, OH | Contract Research |
| , | Acquired by Charles River, Nov 2015, €34M | |
| , | Website down Apr 2024 - Aug 2024 | |
| , | Acquired by Millendo Therapeutics, Dec 2017 | |
| , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences | |
| , | Inactive | |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| , | Renamed Nitrase Therapeutics, 2021 | |
| , | Acquired by BTG plc, May 2016 | |
| Genemod | Edmonds, WA | Lab management software |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab | |
| , | Bought by GSk 2008 | |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| , | Terminated all employees in 2010, shell company | |
| , | Renamed Theriva Biologics, Oct 2022 | |
| , | Acquired by DSM | |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| Bruker | Billerica, MA | Scientific Instruments |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| , | Website down Sep 2024 - Feb 2025 | |
| , | Renamed Lumara Health out of bankruptcy, 2014 | |
| , | Presumed Gone, Nov 2016 | |
| , | Acquired by Brooks Life Sciences, Jul 2017 | |
| , | Renamed Amanta Healthcare, Sep 2014 | |
| , | Acquired by ALX Oncology, Oct 2021 | |
| , | No website. Fisher sells their products | |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| , | ||
| , | ||
| , | Changed Name to Ceptaris Therapeutics Jan 2012 | |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech | |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| , | Acquired by Hibercell, Jul 2020 | |
| , | Bought by Medicis out of Bankruptcy | |
| , | Pivoted out of life science | |
| , | Renamed L2P Research | |
| , | Acquired by abcam, Jan 2015, $28M | |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| , | Website not working May 2021 - Sep 2021 | |
| , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix | |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website down Aug 2024 - Feb 2025 | |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| |
Wuxi, China | WuXi Biologics | Biologics & vaccines CRDMO for antibodies, ADCs, proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| , | Acquired by Merck, Nov 2021, $11.5B | |
| , | Website gone Sep 2022 | |
| , | Renamed Triopsy | |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| , | Acquired by AVI Biopharma 2008 | |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Merged with Zapaq to become CoMentis, Aug 2006 | |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 | |
| , | Renamed BioIVT, Sep 2017 | |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| , | Acquired by NantOmics, Apr 2017 | |
| , | Website down Oct 2023 - Mar 2024 | |
| , | ||
| , | Acquired by AbbVie, Feb 2024, $10.1B | |
| , | ||
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| , | Acquired by Oncothyreon Aug 2014, $27M in stock | |
| , | ||
| , | Website gone Nov 2023 - Mar 2024 | |
| , | Now Avidity Biosciences | |
| GRO Biosciences | Cambridge, MA | Genetically altered bacteria for drug improvement |
| , | Website down Feb 2020 - Apr 2020, presumed defunct | |
| , | Website gone Dec 2015 | |
| , | ||
| Garuda Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| VasoRx | San Diego, CA | RNA delivery |
| , | ||
| , | Acquired by Luminex, Jun 2016 | |
| Emergo by UL | Austin, TX | Medical device consulting |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| , | Gone 2012 | |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream | |
| HepaRegeniX | Tübingen, Germany | Small molecule MKK4 inhibitors to treat acute and chronic liver diseases |
| , | Website Gone, Mar 2017; SBIR | |
| , | Gone 2017 | |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| , | Merged into a joint venture with Patheon | |
| , | Bought by MediGene, Aug 2006, $62.4M | |
| , | Gone, after 2015 | |
| , | Liquidating Jan 2019 | |
| , | Renamed RyCarma Therapeutics, Jan 2025 | |
| Metanotitia | Shenzhen, China | Metabolomic Data Platform |
| , | Renamed ClearNote Health | |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| , | Website down May-Nov 2018 | |
| , | Renamed Assurex Health | |
| , | Acquired by Juno, Jul 2016, $10M + milestones | |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| Repare Therapeutics | Saint-Laurent, QC | Synthetic Lethal Therapeutics |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Ubiquigent | Dundee, UK | Partnered drug discovery & design |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| , | Acquired by Wockhardt, Oct 2007 | |
| , | ||
| , | Acquired by Organon Jun 2021; fka InPress Technologies | |
| , | Not a going concern | |
| InCarda Therapeutics | Newark, CA | Pulmonary drug delivery |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Acquired by CellCarta, Dec 2021 | |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | No news since 2012, presumed gone | |
| , | Acquired by Oxford Gene Technology, Mar 2014 | |
| Curia | Burlington, MA | Contract Research |
| , | No website Mar 2020 | |
| Solu Therapeutics | Medford, MA | Antibody-drug conjugates |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| Camurus | Lund, Sweden | Specialty medicines |
| , | Website down Dec 2020 - May 2021 | |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| , | No news 2018-2023, employees don't list job, CEO is an investor | |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| , | ||
| , | Renamed Invivyd, Sep 2022 | |
| , | Joined Antitope to become Abzena | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Acquired by Abcam, Nov 2015, $20M + $25 milestones | |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| , | Dormant 2020 - Aug 2024 | |
| Evonetix | Cambridge , UK | Desktop Platform for DNA Synthesis |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| , | Website taken over Feb 2025 | |
| , | Acquired by Thermo Fisher, Jul 2017 | |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| , | Bought by BMS, Sep 2010, $885M | |
| , | Website Gone, Company appears to be as well | |
| , | Acquired by Aspen Surgical, Oct 2022 | |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| ReCor Medical | Palo Alto, CA | Catheter-based Hypertension Intervention |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| , | ||
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| , | ||
| , | Acquired by Pasithea Therapeutics, Jun 2022 | |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| , | Website down Jun 2023 - Dec 2023 | |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 | |
| , | Website down Jul 2021 - Oct 2021 | |
| , | No news from 2014-2021, not registered in TN | |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| , | Acquired by Maravai LifeSciences, Mar 2020 | |
| , | Shut Down | |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| SMSbiotech | San Marcos, CA | Extra-cellular Matrix for Research |
| , | ||
| , | Acquired RUA Medical, Mar 2020,, took name | |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 | |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 | |
| , | Seems gone, fka Advanced Biosystems | |
| Prellis Biologics | Hayward, CA | 3D printed vasculature, Antibody Discovery Platform |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. | |
| , | Renamed Scorpius Holdings, Jan 2024 | |
| , | Bankrupt | |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| , | Renamed Orna Therapeutics | |
| , | ||
| , | Merged with CATO SMS, Jan 2022 | |
| , | ||
| , | Renamed Nuventra Pharma Sciences, Sep 2013 | |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| Stendhal | Tlalpan, Mexico | Small Molecules |
| , | Acquired by Fisher Scientific, Jun 2003 | |
| Droice | New York, NY | AI Clinical Data |
| , | Renamed Q32 Bio, Apr 2020 | |
| , | Acquired by Micromet, May 2006 | |
| NX Development | Lexington, KY | Brain Imaging |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 | |
| , | Merged with Ocera Therapeutics Jul 2013 | |
| , | Shut down Mar 2021 | |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| , | Website down Jul 2024 - Dec 2024 | |
| , | Bought by Gilead, Jan 2011, $225M | |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| , | Website down Oct 2022 - Nov 2022 | |
| , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 | |
| Isolation Bio | San Carlos, CA | Microbial Cultivation Device |
| , | Shut down Jun 2017 | |
| , | Website Gone, Sep 2017, Seems gone | |
| Azzur | Hatboro, PA | Consulting |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| , | Dissolved Jan 2014 | |
| , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired | |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| , | No news 2017 - Aug 2024 | |
| , | Acquired by Pace Analytical, Oct 2021 | |
| , | Acquired by Fortis Life Sciences, Feb 2022 | |
| Getinge | Orléans, France | Medical Technology |
| , | Empty website Dec 2019, founded 2011 | |
| , | Tech acquired by Mermaid Medical Grup, Aug 2018 | |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| , | ||
| , | ||
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Veravas | Oakdale, MN | Diagnostics |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Avalo Therapeutics | Rockville, MD | Small molecules for neuro / psychiatric disorders |
| , | Taken over by Shire, Aug 2014 | |
| |
Sorocaba, Brazil | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| , | Bankrupt, Shell Company Now | |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| , | Website Gone, Dec 2018, no employees with pictures on LinkedIn | |
| , | ||
| , | Sold by Apricus to BioTox Sciences Jul 2011 | |
| , | All tech acquired by Ranger Biotechnologies, Jul 2018 | |
| Exploristics | Belfast, UK | Biosimulations software and biostatistics services |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Accord Healthcare | Ahmedabad , India | Generics |
| Remedium Bio | Needham, MA | Gene Therapy |
| Crescendo Biologics | Cambridge, UK | Antibody Fragments |
| , | ||
| Pinnaxis | Noida, India | Pharmacovigilance |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| , | Shut down Feb 2024 | |
| , | Website down Jun 2020 - Sep 2020 | |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| |
Worms, Germany | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| Ethos Biosciences | Philadelphia, PA | Assays & reagents |
| , | ||
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| , | Renamed Vantelix, Feb 2023 | |
| , | Acquired by Evotec, Mar 2007 | |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Dualitas Therapeutics | South SF, | |
| , | Bought by Fresenius Kabi, Jul 2008, $4.6B | |
| NuPulseCV | Raleigh, NC | Circulatory Support Device |
| , | ||
| Clinisys | Tucson, AZ | LIMS Platform |
| , | Acquired by Zevra Therapeutics, Nov 2023, $15M | |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| , | Seems inactive, no employees on LI | |
| Rumi Scientific | New York, NY | Brain-like Organoid |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Pace Analytical | Lenexa, KS | Analytical Testing |
| , | Website down Feb 2024 - Jul 2024 | |
| Rise Biopharmaceutical | , | |
| , | Became Rx3 Pharmaceuticals | |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| Cirtec Medical | Los Gatos, CA | Contract Medical Devices |
| , | ||
| |
Sorocaba, Brazil | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| , | Bankrupt 2009 | |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| , | Dissolved 2013 | |
| Medtronic | Santa Ana, CA | Medical Devices |
| , | Acquired by Thermo-Fisher, Aug 1999, stock | |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| , | Fannin company, seems gone Aug 2024; fka AM Biotech | |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Suvoda | Portland, OR | Clinical Trial Software |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| , | Website down Jul 2021 - Dec 2021 | |
| , | Acquired by Novartis, Dec 2021, $1.5B | |
| , | Renamed Bioelectron | |
| , | Assets acquired by Spinal Elements, Dec 2020 | |
| , | Acquired by GSK Mar 2012 | |
| Fortimedix Surgical | Geleen, Netherlands | Articulating Surgical Instruments |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| CHO-plus | South Sf, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| , | Merged with Cyclo Therapeutics, Sep 2023 | |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| , | Business revoked by NS, Nov 2014 | |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| |
Cranbury, NJ | WuXi Biologics | Biologics & vaccines CDMO for antibodies & proteins from mammalian expression systems. |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| , | ||
| Quantum SI | Guilford, CT | Single-molecule NGS |
| , | ||
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| , | Acquired by Novartis, Apr 2020 | |
| , | Website down Oct 2018, seems defunct | |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune | |
| Pace Analytical | Green Bay, WI | Analytical Testing |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| , | Seems to have been subsumed into Miltenyi | |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| , | Renamed LakeShore Biopharma, May 2024 | |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Texcell | Gronau, Germany | Contract Research |
| Histide | Montpellier, France | Cell Recoding Molecules |
| , | Merged with Brammer, Mar 2016 | |
| , | Acquired by Stryker, May 2023 | |
| , | Website down Dec 2023 - May 2024; fka BigDNA | |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| , | Bought by Thermo Fisher, Jun 2008, $6.7B | |
| , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 | |
| , | Gone as of Oct 2021 | |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| , | Website Gone, Jul 2016 | |
| , | Shut down Dec 2023; Website down May 2024 - Jul 2024 | |
| , | Renamed Annovis Bio, Jun 2019 | |
| , | Acquired by Orthofix, Mar 2018, $105M | |
| , | Changed Name to Aqualis, 2013 | |
| , | Sold Assets, Still Exists | |
| , | ||
| , | Acquired by Rosetta Inpharmatics, Feb 1999 | |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| , | Renamed Canbridge Pharmaceuticals | |
| , | Acquired by Boston Scientific Apr 2015, $62.5M | |
| , | Renamed Blackrock Neurotech, Apr 2022 | |
| , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here | |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| |
Dundalk, Ireland | WuXi Biologics | Biologics & vaccines CDMO for antibodies & proteins from mammalian expression systems. |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 | |
| , | Bought by JnJ, Feb 2003 | |
| , | ||
| , | Website down Sep 2023 - Mar 2024 | |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| , | Merged with Tenpoint Therapeutics, Dec 2024 | |
| Coriell Life Sciences | Philadelphia, PA | Genetic Analysis |
| , | Acquired by Grifols, Mar 2022, $1.27B | |
| , | Renamed Senda Biosciences | |
| , | Shell Company | |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| , | Acquired by Canopy Growth, Oct 2019 | |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| , | Merged with Matrigen to become Selective Genetics, Jul 1998 | |
| , | Shut down Dec 2019 | |
| , | Acquired by Eli Lilly Mar 1994 | |
| , | Acquired by Bayer, Jun 2021 | |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| , | ||
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Celest Therapeutics | , | |
| ReviR Therapeutics | Shenzhen, China | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| , | Gone Jun 2019 | |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| , | Acquired by Laborie, Apr 2018 | |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| , | Website down Oct 2022 - Apr 2023 | |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Renamed Accellix, Jul 2019 | |
| , | Website gone Jun 2020 | |
| Medfiles | Monmouth Junction, NJ | Clinical Consulting |
| , | Renamed Adhesys Medical, Feb 2016 | |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| hVIVO | London, UK | Viral Services |
| Aenova | Tittmoning, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 | |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| , | Dissolved Jun 2021 | |
| , | Acquired by Celsion, Jun 2014 | |
| , | Renamed Vincerx Pharma, Jan 2021 | |
| Collagen Solutions | Glasgow, UK | Collagen |
| physIQ | Naperville, IL | Proprietary personalized analytics and IT platform |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology | |
| , | Acquired by Chiral Technologies, Aug 2015 | |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 | |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| , | Website gone May 2020 - Aug 2021; not in NC business registry | |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 | |
| , | ||
| , | Renamed Cellero, May 2020 | |
| , | Bankrupt, Assets sold May 2024 | |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| , | ||
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| RS Medical | Vancouver, WA | Medical Devices |
| , | Changed name to Nexell Therapeutics, May 1999 | |
| , | Website down Jan 2023 - May 2023 | |
| , | Acquired by Gener8, Feb 2020 | |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| , | Folded into Sartorious after purchasing from Danaher, Oct 2019 | |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| , | Closed 2014, Products seemingly acquired by Greer | |
| , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 | |
| , | ||
| , | Founder left, website gone Oct 2019 | |
| , | ||
| Genomill Health | Turku, Finland | NGS for Liquid Biopsies |
| , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M | |
| , | ||
| , | Shut down early 2021 | |
| , | ||
| , | Acquired by Stryker, Feb 2018, $662M | |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| ProAbtech | Seoul, Korea | Conjugation Chemistry for Biologics |
| , | Single person company with no location | |
| , | Acquired by Baxter, Sep 2013 | |
| Salvat | Miami, FL | Small Molecules |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| , | Acquired by Ixico, Sept 2013 | |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| , | Renamed Theraclone Sciences 2009 | |
| , | Website down Jul 2021 - Nov 2021 | |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| , | Acquired by Qiagen 2006 | |
| , | Website down, Jan 2024 - Jul 2024 | |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| , | Gone, Jun 2014 | |
| , | Website taken over, Sep 2017 | |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| , | Renamed Eurofins Advinus | |
| , | Not FDA registered, Feb 2022, probably all nutraceuticals | |
| Advansta | San Jose, CA | Protein characterization products |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| , | Acquired by eurofins, Dec 2012 | |
| , | Website gone Jul 2015 | |
| , | CEO has about 6 more important jobs, Apr 2020 | |
| , | Four listed employees don’t list as a job on LI, Aug 2022 - Sep 2023 | |
| , | Website gone, twitter gone Aug 2017. One employee on LinkedIn | |
| , | Website for sale Feb 2021 | |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| , | Acquired by Catalent Pharma Solutions, ~Jul 2007 | |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| GUIDED Development | Heidelberg, Germany | Clinical Development Consulting |
| , | Website down Jan 2023 - Jul 2023 | |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| , | Website taken over, Dec 2023 | |
| , | Renamed Immunis.AI | |
| , | Website not updated since 2009 | |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| , | Founder gone 2015, no add'l info | |
| Empatica | Cambridge, MA | Seizure Detection |
| , | Renamed Advanced Biomaterial Systems, Jan 2004 | |
| , | Website taken over Nov, 2024; Business filings late Jun 2024 | |
| VectorY | Amsterdam, Netherlands | Vectorized Antibodies |
| Exosome Diagnostics | Waltham, MA | Biofluid-based molecular diagnostic tests |
| , | Acquired by AMSBIO | |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Ibex Medical | Tel Aviv, Israel | Cancer Diagnostics |
| Galecto Biotech | Copenhagen, Denmark | Galectin-targeting therapeutics |
| , | Website gone Mar 2017, employees gone | |
| , | Shut down Jul 2023 | |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| , | Shut down pre-Aug 2017 | |
| , | ||
| , | Renamed Soricimed Biopharma, 2010 | |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| , | Shut down Sep 2023 | |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| , | Website down Oct 2020 - Jan 2021, presumed gone | |
| Shaperon | Seoul, Korea | Small Molecules, Nanobodies |
| Apertura Gene Therapy | New York, NY | AAV vectors for Gene Therapy |
| , | Acquired by Resilience, Apr 2021 | |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Innoforce Pharmaceuticals | Hangzhou, China | Contract Manufacturing, Biologics, Cell Therapy, Plasmids |
| , | Acquired by Exscientia, Jun 2021 | |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| , | Gone | |
| , | Acquired by Visiox Pharmaceuticals, Aug 2024 | |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 | |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones | |
| Nemaura Medical | Loughborough, UK | Non-invasive Diagnostic Platform |
| , | Rebranded as Exuma Biotechnology, late 2019 | |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| Moderna Therapeutics | Victoria, Australia | RNA Therapies |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| , | Renamed Watchmaker Genomics | |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Lexogen | Vienna, Austria | RNA kits |
| , | Acquired by Impax Laboratories, Mar 2015 | |
| , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 | |
| , | Acquired by Sanofi, Jul 2009, $784M | |
| , | Liquidated, Dec 2019 | |
| Delpharm | Reims, France | Contract Manufacturing |
| , | Closed Mar 2013 | |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| , | Renamed XWPharma | |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| , | ||
| ApiJect | Durham, NC | Single-use injectable delivery system |
| , | Renamed AlloVir | |
| , | Website down, Jul 2023 - Nov 2023 | |
| , | Acquired by Aileron Therapeutics, Oct 2023 | |
| , | Merged with BioSante | |
| TOT Biopharm | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| , | Renamed Seneca Biopharmaceuticals, Oct 2019 | |
| , | Website down Apr 2024 - Aug 2024 | |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| , | Shut down April 2022 | |
| , | Renamed Mytos | |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Vesigen Therapeutics | Cambridge, MA | Fusogenic extracellular vesicle delivery technology |
| ProPharma Group | Deerfield, IL | Consulting |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| , | Shut down | |
| , | Renamed StageZero Life Sciences, Jun 2019 | |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell | |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| GeneTex | Irvine, CA | Research Antibodies |
| JSK Therapeutics | Salt Lake City, UT | Small Molecules |
| , | Website down Sep 2020 - Feb 2021 | |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| , | ||
| , | Acquired by Mylan, Aug 2016 | |
| , | Acquired by CooperSurgical, May 2021, $60M | |
| , | Acquired by PharmaScience, May 2011 | |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| , | No news since 2006 as of Jan 2021 | |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Trudell Medical | London, ON | Inhalation Devices |
| , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol | |
| , | Acquired by INC Research 2011 | |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M | |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| , | Acquired by Helix Medical, Oct 2012 | |
| , | ||
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| , | Assets acquired by Bantam Pharmaceutical, Aug 2015 | |
| , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX | |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| Altasciences | Cypress, CA | Contract Research |
| , | Website gone Jun 2020 - Oct 2020 | |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| EyeBioKorea | Busan, Korea | Ophthalmology Drugs |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| MakroCare | San Francisco, CA | Drug Development Partner |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Merged into Cambrex Oct 1997 | |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| , | Renamed Calliditas Therapeutics, 2017 | |
| , | Inactive, no info | |
| , | Website dated, emails not working, no pictures on LI Sep 2020 | |
| , | Website down Nov 2022 - Mar 2023 | |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| , | Renamed LungLifeAI, May 2019 | |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| iLeadBMS | Gyeonggi, Korea | Small Molecules |
| , | Gone late 2018 | |
| , | Website gone | |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Pharmaron | Cardiff, UK | R&D Services |
| , | Changed name to Asymmetrex, 2014 | |
| , | Founded 2020, no business filings Jan 2022 - Oct 2024 | |
| , | ||
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| , | Dissolved, Dec 2006 | |
| , | Acquired by Keystone Heart, Jun 2020 | |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| , | ||
| Ganymede | Palo Alto, CA | Lab Automation |
| , | Renamed ZelosDx, Jun 2021 | |
| , | Renamed C4X Discovery Jul 2013 | |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| Immunotech Biopharm | , | |
| , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 | |
| Clarity Diagnostics | Boca Raton, FL | Diagnostics |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| AQEMIA | Paris, France | AI Drug Discovery |
| , | Acquired by Alcami, Dec 2021; fka Masy Systems | |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| , | Website down Jul 2021, marked as closed on Google, Employees gone | |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Amador Bioscience | Hangzhou, China | Consulting, Lab Service, Clinical Trial Management |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| , | Acquired by US World Meds 2010 | |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| , | Website down Oct 2022 - Mar 2023 | |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Resolution Bioscience | Kirkland, WA | Next gen sequencing tech for cancer diagnostics |
| , | Bankrupt, Jun 2011 | |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| , | Acquired by NuVo Research | |
| , | Assets purchased by Revivicor, Jun 2005 | |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| , | Website Gone | |
| , | Website gone Apr 2022, not registered in CA | |
| , | No news Aug 2020 - Jan 2025 | |
| , | Acquired by Novotech, Jan 2023 | |
| , | Acquired by MorphpSys, Jul 2021 | |
| , | Acquired by Lonza, Jun 2016 | |
| I-Mab Biopharma | Shanghai, China | Biologics |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| , | Acquired by Abcam, May 2011, $6M | |
| Virometix | Schlieren, Switzerland | Vaccines |
| , | Acquired by Allergan, Feb 2018, $95M | |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| JD Bioscience | Seoul, Korea | Small Molecules |
| , | Website down Aug 2021 - Feb 2022 | |
| Altasciences | Scott Township, PA | Contract Research |
| Enrich Biosystems | Pittsfield, MA | Single Cell Isolation |
| , | Website down Jul 2021 - Jan 2022 | |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| , | ||
| , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics | |
| , | Bankrupt, Jul 2019 | |
| , | Website gone May 2020 | |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| , | Acquired by Ichor Life Sciences, Sep 2021 | |
| , | Website gone Oct 2019, no employees on LI | |
| , | Acquired by Johnson & Johnson, Nov 2006, $1.4B | |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| , | Website gone, Sep-Oct 2017 | |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Renamed Ixaka, Jan 2021 | |
| , | Merged into Bend Bioscience, Sep 2024 | |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research | |
| , | Assets sold to Galileo, Apr 2002 | |
| , | Taken over by a Swiss Instutite | |
| , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own | |
| , | Renamed Magnolia Tejas, 2018 | |
| TreeFrog Therapeutics | Pessac, France | 3D Stem Cell Culture Technology |
| Tonix Pharmaceuticals | North Dartmouth, MA | CNS Disorders |
| Vyriad | Rochester, MN | Immunovirotherapy |
| , | Website gone, Dec 2018 | |
| Ascend Advanced Therapies | Alameda, CA | Gene Therapy CDMO |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones | |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| , | Renamed Longevity Bioedical, 2022 | |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| , | Renamed Millendo Therapeutics, Jan 2016 | |
| , | Renamed Onconetix, Dec 2023 | |
| , | Reorganized as Fibrocell Science | |
| , | Website gone Jun 2021 | |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| , | Website down Oct 2021 - Mar 2022 | |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| , | Website down Jun 2023 - Sep 2023 | |
| , | Acquired by Celltech Group, Nov 2000 | |
| , | Now Cynata Therapeutics | |
| , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 | |
| , | Acquired by Curium, Mar 2020 | |
| BIT Analytical Instruments | Kunshan, China | Contract Manufacturing, Develepment |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Agendia | Irvine, CA | Breast Cancer Assay |
| SoBran | Falls Church, VA | Preclinical Services |
| , | Renamed Pluri, Jul 2022 | |
| Mendaera | San Mateo, CA | Medical Robotics |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Juno Bio Ltd. | London, UK | Vaginal Microbiome Health |
| , | ||
| Deep 6 AI | Pasadena, CA | AI for Clinical Data |
| , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 | |
| Curamys | Seoul, Korea | Stem Cell Fusion Technology |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| , | Website gone Dec 2021 | |
| Alcon | Houston, TX | Eye-Care Products |
| Pfizer | Vienna, Austria | Small Molecules, Biologics, Vaccines |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| , | Gone | |
| , | Merged with distributor, Apr 2024; Sister company of Strekin | |
| , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics | |
| , | Shut down in or before 2020 | |
| , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones | |
| , | Acquired by Charles River, Apr 2019 | |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Acquired by CSL, Aug 2022, $11.7B | |
| , | Acquired by JNJ 2012 | |
| , | Gone, Apr 2019 | |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| , | ||
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| , | ||
| , | Renamed Olpha, Jun 2024 | |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Align Technology | Tempe, AZ | Teeth alignment |
| |
Hombourg, France | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| , | ||
| , | ||
| , | Business revoked Aug 2019 | |
| , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 | |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| , | Part of AmMax | |
| , | Acquired by CureVac, Jun 2022 | |
| , | Renamed Sonablate, Jul 2021 | |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| Daré Bioscience | San Diego, CA | Women's Health |
| , | Acquired by Receptos | |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| |
South Haven, MI | Grace Fine Chemical | U.S. Domestic CDMO offering process scaleup and commercialization of small molecule APIs, RSMs and intermediates. Network of 2 fully integrated sites with a world class analytical team offers an industry-leading flexible supply chain through the back integration of its intermediates. |
| Polpharma | Starogard Gdanski, Poland | Generics |
| , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis | |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| , | Renamed SAB BIO | |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| , | Renamed Fractyl Health | |
| , | Acquired by Ecolab, Oct 2021, $3.7B | |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| , | Website gone, Jan 2019 | |
| , | Renamed eXoZymes, Feb 2025 | |
| , | Acquired by Element, Mar 2021 | |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| , | Residential address, three employees, no money | |
| RADLogics | Tel Aviv, Israel | Healthcare software AI |
| , | Renamed Allarity Therapeutics | |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| , | SBIR recipient, no info | |
| , | Acquired by Novartis, Jul 2023, $500M + $500M milestones | |
| , | Shut Down May 2017 | |
| , | Renamed Nexelis, Sep 2019 | |
| , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx | |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO | |
| , | ||
| , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 | |
| , | Renamed CytoCore | |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| , | Renamed Entero Therapeutics | |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| , | Renamed ClinChoice, Sep 2020 | |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| Verséa Health | Tampa, FL | Diagnostics |
| , | Unknown Fate | |
| , | Acquired by Exact Sciences, Nov 2019, $2.8B | |
| , | Acquired by GSK | |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| , | Presumed gone | |
| , | Still technically active Jan 2022, but no progress in a decade | |
| , | Majority of assets acquired by Timber Pharmaceuticals, 2019 | |
| , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 | |
| Santiago Custom Chemicals | Prague, Czech Republic | Chemical Synthesis Services |
| Genoox | Palo Alto, CA | Genetic Data Analysis |
| , | Renamed Virscio, Jan 2020 | |
| , | Acquired by Valo Health, Apr 2022 | |
| Medicure | Princeton, NJ | Small Molecule |
| BrainsWay | Burlington, MA | Device for Brain Disorder Treatment |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Overture Life | New York, NY | Embryology Lab in a Box |
| , | Merged with Second Sight to become Vivani Medical, Aug 2022 | |
| , | Acquired by Schrödinger, Jan 2022, $6M | |
| , | Sold off products Feb 2019, not sure what they're doing, website gone | |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| , | Renamed NXI Therapeutics | |
| , | Acquired by Relay Therapeutics, Apr 2021, $85M | |
| , | Website Down May 2024 - Nov 2024 | |
| , | Acquired by UniQure | |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| , | Acquired by Merck, Jan 2016, $400M | |
| , | Assets Sold | |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| , | Acquired by Takeda, Oct 2021, $525M | |
| |
Greensboro, NC | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| iThera Medical | Munich, Germany | Optoacoustic Imaging |
| , | Gone Sep 2016 | |
| , | ||
| Mytos | London, UK | Automated Cell Culture |
| , | ||
| , | Acquired by Gardner Denver | |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| , | More of an aspiration than a company | |
| , | Acquired by BioNTech, Feb 2025 | |
| , | No business filings Jan 2020 - Nov 2023 | |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| , | Website gone Jul 2023 | |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| , | Website down Feb 2021 - Apr 2021 | |
| , | Graduated from Jlabs, Jan 2016, no info since then | |
| , | Renamed Recludix Pharma, Mar 2020 | |
| , | ||
| , | Acquired by Wright Medical group Apr 2013 | |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| , | Renamed Incendia Therapeutics, Aug 2023 | |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| , | Acquired by Covance, Jul 2020 | |
| , | Bought by Gilead 2010 | |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| , | Acquired by PhoenixBio, Dec 2017 | |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| , | Renamed Dina Pharmaceuticals, 2016 | |
| , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything | |
| , | Merged with Celsus to become Akari Therapeutics, Aug 2015 | |
| Eversana | Chicago, IL | Commercialization Consulting |
| , | Acquired by Hillrom, Aug 2019, $130M | |
| , | Acquired by Biovitrum, Mar 2005 | |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| , | Merged with Apexis Bio | |
| , | Acquired by CyberKinetics, Feb 2006 | |
| , | Acquired by Pfizer 2005 | |
| ImmunityBio | El Segundo, CA | Cellular therapy |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address | |
| , | Acquired by Sucampo, Aug 2015, $276B | |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| , | Gone 2009 | |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| , | Spun off, Renamed Zoetis Jul 2013 | |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| , | Acquired by Catalent, May 2019, $1.2B | |
| , | Bought by Shire 2011, Now Shire Regenerative Medicine | |
| , | Bought by Mirati Therapeutics Jun 2013 | |
| , | Acquired in Reverse Merger, entity renamed Inventa Biotech | |
| , | Website gone | |
| Venn Life Sciences | Dublin, Ireland | Clinical Trial Solutions |
| , | Website down Oct 2021 - Feb 2022 | |
| , | Acquired by Qiagen Aug 2011 | |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| , | Changed name to Poniard, May 2006 | |
| Idience | Seoul, Korea | Cancer Therapies |
| , | Now Chikojee Therapeutics (more or less) | |
| , | Created 2003, no updates since 2011 as of Dec 2019 | |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| , | Shut down Jul 2022 | |
| , | Merged with MedQIA to become Voiant Clinical, Sep 2023 | |
| , | ||
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| , | ||
| , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 | |
| , | Renamed Infinant Health | |
| , | Gone | |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| , | Acquired by BD, Jul 2021 | |
| , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming | |
| , | Gone | |
| , | Changed Name to Trine Pharmaceuticals 2004 | |
| Psomagen | Rockville, MD | Genetic Sequencing |
| , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active | |
| , | Renamed hVIVO | |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| , | Absorbed by ViaCyte, Feb 2016 | |
| , | Shell company | |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| , | Shut down Dec 2017 | |
| BrainsWay | Jerusalem, Israel | Device for Brain Disorder Treatment |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M | |
| , | Shut down 2010 | |
| , | CA-based, Presumed defunct | |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| NovaLead Pharma | Pune, India | Small Molecules |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| , | No news 2017-2023 | |
| , | Gone | |
| , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics | |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| , | Gone 2014 | |
| , | Acquired by Diasorin, Apr 2021, $1.8B | |
| Bausch Health | Laval, QC | Small Molecules |
| Kivu Bioscience | San Francisco, CA | ADCs |
| , | Acquired by Vividion Therapeutics, Jan 2025 | |
| MILabs | Houten, Netherlands | Molecular Imaging |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| , | Website down Mar 2022 - Sep 2022 | |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| , | Renamed Vaxxinity | |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| veranova | Wayne, PA | CDMO - APIs, Biologics |
| , | Filed Chapter 7, Jun 2016 | |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| , | Website down Dec 2019 - Mar 2020 | |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Bayer | Bergkamen, Germany | Small Molecules |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Johnson and Johnson Innovative Medicine | South SF, CA | Small Molecules, Biologics |
| , | Renamed Apyx Medical, Dec 2018 | |
| , | Website down Feb 2023 - Jul 2023 | |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| , | Acquired by Caprion Biosciences, Sep 2018 | |
| , | Renamed PredxBio, Apr 2023 | |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix | |
| , | Bankrupt Aug 2024 | |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| , | Technology bought by Nia Therapeutics, Jul 2019 | |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| , | Chapter 11 Bankruptcy, Nov 2021 | |
| , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M | |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| , | Merged with Cephalon, Oct 2000 | |
| , | Acquired by Pharmaron, Oct 2020 | |
| , | Reverse merged by Yumanity, Dec 2020 | |
| , | Website Gone 2-19-14, 10-14-14 | |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| , | Acquired by KBI Biopharma, Jun 2017 | |
| , | Changed named to Valerion Therapeutics 2012 | |
| , | Website down Jan 2018 - Feb 2018, Emails bouncing | |
| , | ||
| , | Renamed Panbela, Dec 2020 | |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 | |
| , | Bought by Seattle Genetics, Feb 2018, $614m stock | |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 | |
| , | ||
| Cipla | Verna, India | Generics, APIs, Formulation |
| , | Acquired by Simulations Plus, Jun 2023 | |
| , | Acquired by Deltagen, Dec 2009 | |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| , | Shut down 2022 | |
| , | Bought by Dassault, 2014 | |
| , | Changed name to Astex Pharmaceuticals | |
| , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration | |
| , | Shut down Nov 2024; LI gone Nov 2023 | |
| , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company | |
| , | Website gone Nov 2017 | |
| , | Russian company acquired by Ovoca Bio, 2018 | |
| , | ||
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 | |
| , | Website down Feb 2021 - Jul 2021 | |
| |
Wuppertal, Germany | WuXi Biologics | Biologics & vaccines CDMO for antibodies & proteins from mammalian expression systems. |
| , | Acquired by Chiroscience, Nov 1996, $120M stock | |
| , | ||
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| , | Acquired by Valo Health, Jul 2021 | |
| , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 | |
| , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam | |
| , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 | |
| , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M | |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| Genomadix | Kanata, ON | Portable PCR |
| , | Acquired by Thermo Fisher | |
| , | Acquired by BD, Dec 2017, $24B | |
| , | ||
| , | Website down Mar 2024 - Jul 2024 | |
| , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex | |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| Iconovo | Lund, Sweden | Inhalation Technology |
| , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 | |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| , | Shut down | |
| CG Pharmaceuticals | Seoul, Korea | Proprietary Drug Discovery Platform |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo | |
| , | Acquired by Surterra Wellness | |
| Novozymes | North Rocks, Australia | Enzymes |
| , | Merged with Q-State Biosciences, Nov 2018 | |
| , | Bought by Bharat Biotech, Feb 2019 | |
| , | ||
| , | ||
| , | Acquired by ResMed, Dec 2018, $225M | |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Invivotek | Trenton, NJ | Pre-clinical CRO with expertise in in vivo pharmacology & phenotypic characterization of genetically modified rodents. |
| , | No news in six years as of Mar 2019. No employees on LinkedIn | |
| , | Renamed Apex Bioscience, 1994 | |
| Myeloid Therapeutics | Cambridge, MA | Cell Therapy for Cancer |
| , | Bought by Agenus, Jan 2014, $10M | |
| , | ||
| , | Gone | |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Now GeneNews | |
| , | Merged with Immunome, Oct 2023 | |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| , | Renamed eCential Robotics, Jan 2021 | |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| , | Acquired by Charles River, Jul 2014 | |
| , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name | |
| Orchid Orthopedic Solutions | Arcadia, CA | Contract Medical Device Work |
| , | Merged with Covalution Bioscience to become Acerta Pharma | |
| , | Shut down Sep 2022 | |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| , | Acquired by Avanos, Nov 2019 | |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones | |
| , | Website gone, Mar 24, 2015 | |
| , | Shut down Nov 2019 | |
| Avia Pharma | Danderyd, Sweden | In-licensing, Acquisitions |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| , | Now Cognate Bioservices | |
| , | Bought by Meda, $350M, Oct 2010 | |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 | |
| , | Apparently Gone | |
| , | ||
| , | Acquired by Deinove, May 2018 | |
| , | Website down May 2022 - Oct 2022 | |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| BioTeam | Middleton, MA | Scientific IT consulting |
| , | Changed name to Artermis Therapeutics, Dec 2016 | |
| MindMed | New York, NY | Psychedelic-Inspired Drugs |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 | |
| , | ||
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| , | Website down Sep 2022 - Feb 2023 | |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| , | Acquired by Treximo, Mar 2019 | |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| , | Rebranded as Precision Motion Health, Sep 2024 | |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| , | Acquired by Emergent BioSolutions Aug 2010, $97M | |
| Viva Biotech | Jiaxing , China | Contract Research |
| , | Acquired by Restech, Jun 2020 | |
| , | ||
| , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares | |
| Siegfried | Nantong City, China | Contract Drug Manufacturing, APIS, Development |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 | |
| , | Acquired by Nutriband, Sep 2018, $2.7M | |
| , | ||
| , | Acquired by Karo Bio Nov 2000 | |
| , | Website down, Oct-Dec 2017 | |
| Terumo Medical | Somerset, NJ | Medical Devices |
| , | Website down Jan 2020 - Dec 2020 | |
| , | ||
| , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 | |
| Catalyst Clinical Research | Cheshire, UK | Clinical research solutions to the global biopharmaceutical industry |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| , | Acquired by Atlas Chemical Industries | |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| , | Reverse merged with Immunic Therapeutics, Apr 2019 | |
| OneCell Diagnostics | Mumbai, India | Cancer Diagnostics |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| , | No longer active, just looking to license their technology, website gone Apr 2019 | |
| , | Xcovery offshoot. Co-located, same employees | |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| , | Gone | |
| HebeCell | Natick, MA | Cell Therapies |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| , | Defunct | |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| , | ||
| , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 | |
| Peptech | Bedford, MA | Chemistry Services |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| , | Acquired by Mylan, Jul 2008 | |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| , | Marked as closed on Google, Nov 2019 | |
| , | Now part of TekniPlex Healthcare | |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| ChitogenX | Kirkland, QC | Novel therapeutic tissue repair technologies to improve the natural healing process of body tissues |
| , | Bought by Amicus Aug 2015, $229M+$618M milestones | |
| , | Website down Apr 2024 - Aug 2024 | |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| , | ||
| , | Failed to file business docs, dissolved Jun 2019 | |
| , | Renamed Cognoptix | |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Corza Medical | Shanghai, China | Surgical Devices |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| , | Renamed SB Drug Discovery | |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| , | Gone 2012 | |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| , | Website down Sep 2024 | |
| , | Gone | |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Accellix | Jerusalem, Israel | On-demand Assays |
| , | Website down Jan 2021 - May 2021 | |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Bimini Health Tech | Solana Beach, CA | Tissue & Cell-Based Regenerative Medicine |
| , | Website down Mar 2023 - Sep 2023 | |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 | |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| , | Website gone Aug 2020 - Feb 2022 | |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| , | Acquired by Bio-rad, Jul 2001 | |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| , | Changed name to NovaScreen Biosciences, Sep 2000 | |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Sedana Medical | Danderyd, Sweden | Anesthetic Conserving Device |
| , | ||
| , | Gone | |
| , | Now Apricus Bio | |
| , | Website gone Sep 2017 | |
| , | Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 | |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Teclison | Princeton, NJ | Cancer Therapies |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| , | Bought by JnJ 2005 | |
| , | Acquired by Gilead, Oct 2020 | |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| , | Voluntarily Liquidated, Sep 2009 | |
| , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 | |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| , | Bankrupt | |
| , | Acquired by Janssen, Jun 2012 | |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Adragos Pharma | Halden, Norway | Formulation, Manufacturing, Analytical, PD, Tech Transfer, Stability |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| , | Gone by 2020 | |
| , | Acquired by Impax Laboratories, Mar 2015 | |
| , | Renamed Evrys Bio, Aug 2019 | |
| , | Acquired by Schwarz Pharma, Jul 2005 | |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Renamed Juniper Pharmaceuticals, Apr 2015 | |
| , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 | |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| , | ||
| , | Acquired by Horizon Pharma, Oct 2016, $800M | |
| Alpha Genesis | Yemassee, SC | Nonhuman Primate Products |
| , | ||
| , | ||
| , | Bankrupt, Feb 2015 | |
| , | Acquired by Frontage, Apr 2021 | |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| , | Acquired by Alexion, Jun 2015, $8.4B | |
| , | ||
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| , | No website Nov 2018 - Feb 2024 | |
| , | ||
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| , | Website down Sep 2024 - Feb 2025 | |
| , | Merged into DIAGNOS Inc | |
| , | Acquired by Alexion | |
| , | Bought by Vectura, €130M, Mar 2014 | |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Viwit | Shanghai, China | APIs, Formulation |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Jacobus Pharmaceuticals | , | Compounded Drugs |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| , | Renamed hVIVO, Apr 2015 | |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| , | Now Novoste | |
| , | Acquired by Capsugel, Sep 2013 | |
| , | Changed name to Targazyme | |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| , | Bought by J&J | |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| , | Merged with isoray to become Perspective Therapeutics, Feb 2023 | |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| , | ||
| , | ||
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| , | Gone | |
| , | Acquired by Horizon Pharma, Sep 2014 | |
| Sidewinder Therapeutics | San Diego, CA | Large Molecule Precision Therapeutics |
| , | Bought by Alcan | |
| , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 | |
| , | Acquired by Amgen, Feb 2013, $111M | |
| , | ||
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel | |
| , | Changed name to Athenex | |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| , | Acquired by Novartis, Feb 2019 | |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| , | Shut down 2010 | |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| , | Renamed MGC Diagnostics, Aug 2012 | |
| GeneDx | Stamford, CT | Genetic Data |
| , | Lx Therapies, May 2011 to become Laurantis Pharma | |
| , | Acquired by Caldera Medical, Sep 2023 | |
| Sharp | Rhymney, UK | Contract clinical trial services and commercial packaging services |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| , | Website down Aug 2023 - Apr 2024 | |
| , | Award in 2008, No additional info, presume defunct | |
| , | Website gone Jul 2020 | |
| Minimum Bio | Surry Hills, Australia | Cellular Target Identification for Drug Discovery |
| , | ||
| Tasso | Seattle, WA | Blood-collection products |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| , | Renamed Azurity Pharmaceuticals, Jun 2019 | |
| , | Bankrupt 2015 | |
| , | Basically Bust | |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Website down Oct 2020 - Feb 2022 | |
| Crown Bioscience | San Diego, CA | Drug Development |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| , | No progress, not registered in CA, website broken and under construction for years | |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| , | Acquired by Illumina, Jun 2022 | |
| Caranx Medical | Nice, France | Surgical, Robot Imaging |
| , | Renamed Alseres Pharmaceuticals, Jun 2007 | |
| , | Acquired by BresaGen, Nov 2000 | |
| , | Founder left, Site taken over Aug 2017 | |
| Avatamed | Singapore, Singapore | Precision Oncology |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Akero Therapeutics | South SF, CA | NASH therapy |
| , | Acquired by UL, 2018 | |
| |
Comu, Romania | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Website down Jul 2021 - Sep 2021; not a registered CA business | |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| , | No info since 2013, not registered in MD | |
| , | Bought by Warner-Lambert, 1997 | |
| , | Renamed Structure Therapeutics, Aug 2022 | |
| , | Acquired by Citius Pharmaceuticals, Mar 2016 | |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 | |
| , | ||
| , | part of Sumitomo; aka SDP Oncology | |
| , | Gone Jan 2021 | |
| , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies | |
| Xpamac | Szeged, Hungary | Cell Line Development |
| Carcinotech | Roslin, UK | 3D printed tumors |
| , | Renamed CGI Pharmaceuticals | |
| , | Renamed Pharmanovia | |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| , | Changed company name to Neothetics, Aug 2014 | |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| , | Sold discovery platform to Locus Biosciences, Jul 2018 | |
| ChemPacific | Baltimore, MD | Chemicals |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| , | Website gone Aug 2018 | |
| , | Changed name to CareDx | |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| |
Brunswick, ME | InSphero | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| , | Website gone Oct 2018, CEO gone | |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 | |
| , | Acquired by Exactech, Jan 2008 | |
| Theravance Biopharma | South SF, CA | Small Molecules |
| , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M | |
| EuroscreenFast | Gosselies, Belgium | GPCR Screening |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | ||
| , | Website down Jun 2023 - Dec 2023 | |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| , | Renamed Mayne Pharma, Nov 2010 | |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| Ergomed | Geneva, Switzerland | Clinical Research |
| , | Acquired by Mallinckrodt, Apr 2015 | |
| , | ||
| , | Renamed Atossa Therapeutics, Jan 2020 | |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Parasym Health | London, UK | Neurostimulation of the ear to treat chronic and inflammatory health conditions |
| |
Schlieren, Switzerland | InSphero | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 | |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| , | Bought by Lonza, Dec 2016, $5.5B | |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Avalyn Pharmaceuticals | Seattle, WA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| , | Acquired by LifeNet health, Nov 2016 | |
| , | Gone | |
| , | Website gone Sep 2017 | |
| , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna | |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| , | Acquired by Arrant Bio, Nov 2019 | |
| , | Acquired by Trinity Biotech, Sep 2024 | |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| , | Acquired by Entremed, Jan 2006 | |
| , | Reincorporated in Caymans, took new name inRegen | |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) | |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| , | Gone | |
| Vertex | San Diego, CA | Small Molecules |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| , | Employees all moved on, Aug 2023 | |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| , | Presumed Gone | |
| , | Renamed Axcella Health, Jun 2016 | |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| , | ||
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| , | Gone | |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| Kerafast | Shirley, MA | Reagents for the Greater Good |
| , | Website down Apr 2022 - Jul 2022 | |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| ReSync Bio | San Francisco, CA | Software Integration |
| , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 | |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| , | Shut down Jan 2022 | |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| , | Gone, 2002? | |
| , | Gone Feb 2020 | |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| 89bio | San Francisco, CA | Liver Treatments |
| , | Website not working, Aug 2020; no LI employees | |
| Fist Assist Devices | Los Altos, CA | Vein Compression Device |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| , | Bought by Takeda, May 2013 Announced | |
| Beckley Psytech | Beckley, UK | Psychedelic Compounds |
| , | Acquired by CellCarta, May 2021 | |
| DM Clinical Research | Houston, TX | Clinical Research |
| , | ||
| Axxam | Milan, Italy | Drug discovery services |
| , | Website gone Apr 2018 | |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| , | Website down Mar 2022 - Sep 2022 | |
| , | Been around since 2008, but no site or current info | |
| Excellos | San Diego, CA | Cell & Gene Therapy CDMO |
| Biogen | Durham, NC | Small Molecules, Biologics |
| , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 | |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| , | Acquired by AGC Biologics, Sep 2021; aka MolMed | |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Septerna | South SF, CA | GPCR Drug Discovery |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| , | Renamed Acelity after KCI & Lifecell acquisitions | |
| , | Ancient website, no news 2014-2023 | |
| , | Liquidated Jul 2008 | |
| TE Connectivity | Berwyn, PA | Medical Devices |
| , | Shut down, Dec 2022 | |
| , | Liquidated, Oct 2023 | |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| |
Shanghai, China | WuXi Biologics | Biologics & vaccines CRDMO for antibodies, ADCs, proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| , | Gone 2016 | |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| , | Website gone, CEO Gone, Presumed gone | |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| Formurex | Stockton, CA | Contract Research |
| , | Gone | |
| , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 | |
| , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics | |
| Domain Therapeutics | Illkirch-Strasbourg, France | Small Molecules |
| , | Renamed BioNxt Solutions, Nov 2022 | |
| , | Renamed Claritas, Apr 2021 | |
| , | Acquired by HiRo | |
| , | Website down Jan 2024 - Jul 2024 | |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Cristers | Suresnes, France | Generics |
| , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 | |
| , | Acquired by Resilience, Dec 2021 | |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| , | Website redirects to AltraBio, Feb 2019 | |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| , | Assets acquired by Pierre Fabry, May 2017 | |
| , | ||
| , | Acquired by Endo Pharmaceuticals 2009 | |
| , | Renamed AnchorBio Solutions | |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| , | Now Capstone Therapeutics | |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| , | Website down Apr 2021 - Sep 2021 | |
| , | Gone | |
| Meletios Therapeutics | Paris, France | Antivirals |
| , | Rebranded as S-bio | |
| , | Renamed Arovella, Oct 2021 | |
| Hemanext | Lexington, MA | Transfusion Technologies |
| |
Bloomington, IN | Catalent | Biologics Manufacturing & Cell Line Development |
| , | Website down Jul 2022 - Aug 2022 | |
| BridgeBio Oncology Therapeutics | South SF, CA | RAS-targeted small molecules |
| , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 | |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| , | Merged with VIA Pharmaceuticals, Jun 2007 | |
| Recipharm | Yavne, Israel | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| bluebird bio | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| , | Gone | |
| Ackley Machine | Moorestown, NJ | Tablet Machines |
| HawkCell | Lyon, France | MRI Research Technology |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| MExbrain | Villeurbanne, France | Biopolymer treatments against conditions involving metals toxicity |
| Meiji Seika Pharma | Tokyo, Japan | Specialty, Generics, Consumer Products, Contract Manufacturing |
| , | Acquired by Monogram Energy Oct 2009 | |
| , | Acquired by Intrexon | |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| , | Acquired by The Medicines Company, Feb 2015 | |
| , | Changed name to Innoviva, Jan 2016 | |
| , | Renamed Kuur Therapeutics, Mar 2020 | |
| Rezolute | Redwood City, CA | Biologics |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| , | Acquired by Spetcrum Plastics | |
| , | Acquired by BD, May 2008 | |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| , | Bought by Sanofi 2010 | |
| , | Execs both left late 2019 | |
| , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones | |
| Redbiotec | Schlieren, Switzerland | Various Biologic Modalities |
| , | ||
| , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock | |
| , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics | |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| , | Website taken over Jan 2019 | |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| , | Acquired by Mizuho OSI, Sep 2020 | |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| , | Not active CA business 2017 - Dec 2024 | |
| , | Bought by St. Jude Medical, Oct 2015, $3.4B | |
| , | Renamed Cyclo Therapeutics | |
| Tactiva Therapeutics | Buffalo, NY | Adoptive Cell Therapy |
| , | Website Under Construction Dec 2019 - Oct 2020 | |
| Shuttle Pharmaceuticals | Gaithersburg, MD | Sensitizing cancer to radiation |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| , | Acquired by Myriad Genetics, Nov 2022 | |
| , | Acquired by Theracon, Oct 2018 | |
| Elixirgen Scientific | Baltimore, MD | Cells for Drug Screening |
| , | Renamed Avata Biosciences, May 2024 | |
| AbCheck | Plzen, Czech Republic | Antibody Discovery |
| , | ||
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| , | Acquired by Unchained Labs, Jun 2015 | |
| , | Shut down 2023 | |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| , | Bought by NuVasive, Jul 2016, $98M | |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| |
Somerset, NJ | Catalent | Oral Dosage Manufacturing |
| , | No website May 2019, founded 1997 | |
| , | ||
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| , | Acquired by Boston Scientific, Feb 2011 | |
| , | Renamed Alanza | |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| OnQuality Pharmaceuticals | Seattle, WA | Treatments for cancer side effects |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecules |
| , | Shut Down Jun 2022 | |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Venebio | Glen Allen, VA | Consultants |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| , | Website copyright 2004 (as of 2018) | |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| , | Website down Jun 2022 - Aug 2022 | |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Princeton Separations Scientific | Monmouth Junction, NJ | Separation Technology |
| , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology | |
| , | Acquired by Charles River Labs, Oct 2002 | |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| , | Sold assets, Sep 2007 | |
| , | Business Registration Revoked, Jul 2019 | |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Calixar | Lyon, France | Membrane Proteins |
| , | Shut down Dec 2021 | |
| Intersect Diagnostics | New York, NY | Novel biomarker signatures for precision therapeutics |
| , | Shut down 2017 | |
| , | Acquired by HIL Applied Medical, Jun 2016 | |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| , | Website gone, Mar 2019 | |
| , | Bought by Integra Life Sciences, Jun 2015 | |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 | |
| Notch Therapeutics | Seattle, WA | Gene-modified T cell therapy |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| , | Website down Jan 2020 - Feb 2020, Employees gone | |
| , | Now part of X-37 | |
| , | ||
| , | ||
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| Microbot Medical | Braintree, MA | Micro-robot assisted medical technologies |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| , | Website gone, key assets acquired by AmpliPhi Jan 2016 | |
| , | Likely acquired by ALK-Abello, Dec 2016 | |
| , | Acquired by Cantel Medical, Sep 2015 | |
| , | Renamed Enara Bio, Jun 2020 | |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Trilations | New York, NY | Strategic Consulting |
| , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 | |
| , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior | |
| 908 Devices | Boston, MA | Pre-Mass spec prep device |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| , | Bought by Lilly, 1986, $400M+ | |
| , | Acquired by China Sky One, $428k, Apr 2008 | |
| , | Bought by Sarepta, May 2019, $165M | |
| , | Acquired by Millennium 1999 | |
| TME Pharma | Berlin, Germany | L-aptamers |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| , | Renamed RepliCel Life Sciences | |
| , | Not registered in MA, Nov 2022 - Dec 2023 | |
| , | Website down Nov 2023 - Mar 2024 | |
| , | ||
| Xegen | Gemenos, France | NGS Data Analysis |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| , | Acquired by Boehringer Ingelheim 2008 | |
| , | Folded into BridgeBio, Sep 2023 | |
| Atraverse Medical | Cardiff by the Sea, CA | Transeptal access technologies |
| Allucent | Rockville, MD | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| , | ||
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| , | Renamed Veraxa Biotech, Jun 2021 | |
| Parexel | Hackensack, NJ | Clinical Research |
| Bristol Myers Squibb | Manati, PR | Biologics |
| , | Acquired by J&J, Oct 2020, $6.5B | |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| , | Merged with Silence Therapeutics 2009 | |
| , | No website Dec 2019 - May 2023 | |
| , | ||
| , | Gone 2002 | |
| , | Website gone Apr 2019, Seems defunct | |
| , | Website down Nov 2023 - Mar 2024 | |
| , | Website gone Jan 2022 | |
| Emglev Therapeutics | Paris, France | Synthetic Single-Domain Antibodies |
| , | Bought by Patheon, Aug 2014 | |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| , | Seems gone, Jul 2022 | |
| , | ||
| Becton Dickinson | Durham, NC | Lots of Biotechnology Products |
| , | Acquired by Coherus, Sep 2023, $65M | |
| , | Agreed to be acquired, but uncertain if it happened | |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| , | Acquired by Sanofi, 2011, $20.1B | |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| Smithers | Akron, OH | Contract Research |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| , | Renamed ISIS, Jul 2019 (for real), no website | |
| , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 | |
| , | Renamed Sphere Bio, Feb 2025 | |
| , | ||
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| , | ||
| , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 | |
| OncoBay Clinical | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Novotech | Auckland , New Zealand | Clinical Research |
| AB Science | Paris, France | Small Molecules |
| , | Merged with PathoGenomix, Sep 2015 | |
| , | Shut down May 2024 | |
| , | ||
| , | Acquired by Matinas Biopharma, Jan 2015 | |
| , | Received SBIR in 2004, no website, no employees | |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| , | Acquired by Accel Clinical Research, Jun 2020 | |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| , | Renamed Qnovia, Sep 2022 | |
| Promaxo | Oakland, CA | Small form MRI |
| Karius | Redwood City, CA | Diagnostics |
| , | Merged with Cortex Pharmaceuticals Aug 2012 | |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| , | Website Gone, Oct 2018 | |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| , | Bought by Novartis, Dec 2016 | |
| Instapath | Houston , TX | Automated Digital Pathology |
| , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations | |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| , | Bought by Integra Life Sciences, Oct 2017, $1.045B | |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| , | Website down Jan 2020 - Oct 2020 | |
| Synoligo | Morrisville, NC | Oligonucleotide Synthesis |
| , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active | |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| , | Website down Aug 2023 - Apr 2024 | |
| Romark Laboratories | Tampa, FL | Small Molecules |
| , | ||
| , | Renamed RespireRx Pharmaceuticals, Dec 2015 | |
| , | Website gone Jan 2022 | |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Pharmaron | Beijing, China | R&D Services |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| TrialStat Solutions | Montreal, QC | eClinical |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| , | Bought by Paladin 2011 | |
| , | Renamed Fore Biotherapeutics, Feb 2021 | |
| , | Acquired by Elanco, Oct 2016, $885M | |
| , | Presumed gone, not too serious in first place | |
| , | Website Gone Oct 2015 | |
| , | Acquired by Metabolon, Aug 2012 | |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| , | Website taken over Aug 2020 | |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Pharma Consulting Associates | Oceanside, CA | Consulting |
| , | Renamed Alydia Health, Sep 2018 | |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Acquired by Trescal, Jan 2022 | |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| , | ||
| Flomics | Barcelona, Spain | Molecular Biopsies |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| , | Acquired by Stryker, Sep 2021 | |
| , | Renamed PBL Assay Science | |
| NEC Oncoimmunity | Oslo, Norway | Proprietary machine-learning based software |
| , | Changed name to LV Informatics, May 2018 | |
| , | Shut down 2002 | |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| , | Renamed Barinthus Biotherapeutics, Nov 2023 | |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| , | Not a registered business in CA, website not working Dec 2020 | |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 | |
| , | Bought by Lilly, Oct 2008, $6.5B | |
| , | Gone, 2013 | |
| CyMedica Orthopedics | Scottsdale, AZ | Muscle Stimulation Device |
| , | Bought by Accelrys Jan 2012 | |
| Synedgen | Claremont, CA | Biofilm Control |
| NeuroWave Systems | Beachwood, OH | EEG |
| icometrix | Boston, MA | Imaging AI |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| , | Changed name to Epoch Biosciences, 2000 | |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| , | Bought by NuVasive, Jan 2016, $380M | |
| , | Assets acquired by Winco, Jun 2015 | |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| , | Merged into Catalyst Biosciences, Aug 2015 | |
| , | ||
| , | Merged with Tau Therapeutics to become Cavion, Aug 2014 | |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Revitope Oncology | Concord, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| EDAP TMS | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| preclinics | Parma, Italy | Contract Research |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| TRPHARM | Istanbul, Turkey | Small Molecules? |
| , | Website gone Aug 2022 | |
| DLK Medical Technologies | Dallas, TX | OTC |
| |
Curtis Bay, MD | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 | |
| , | Renamed Acrivon Therapeutics, May 2018 | |
| , | Acquired by Alcon, Feb 2016, up to $740M | |
| , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 | |
| Mepha | Basel, Switzerland | Generics |
| Isomerase Therapeutics | Cambridge, UK | Biosynthetic medicinal chemistry services |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| , | Gone | |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| , | ||
| , | ||
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Aenova | Starnberg, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| GSK | Gloucestershire, UK | Small Molecules, Vaccines, Biologics |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Genmab | Utrecht, Netherlands | Biologics |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| , | Website not working Apr 2021 - Aug 2021 | |
| , | Acquired by BD, Mar 2015 | |
| Pulnovo Medical | Wuxi, China | Cardio Devices |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| , | Website gone Jun 2020 | |
| , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG | |
| , | Acquired by LGC, Dec 2024 | |
| SRI International | Menlo Park, CA | Independent Research |
| , | Gone | |
| , | ||
| , | Acquired by Baxter, Jun 2020 | |
| , | Changed name to Avidimer Therapeutics, May 2005 | |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Natco Pharma | Telangana, India | Generics, APIs, Contract Manufacturing |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| , | Renamed Oncodesign Services, Mar 2022 | |
| , | Website down Aug 2024 - Sep 2024; Professor side gig | |
| , | Website gone Oct 2019 - Dec 2020 | |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google | |
| Boston Scientific | Marlborough, MA | Medical Devices |
| , | Website gone Jan 2020 | |
| , | Gone 2001 | |
| Clario | Bridgewater, NJ | Clinical Services |
| , | Shut down 2024; Website down Nov 2024 - Jan 2025 | |
| , | Bought by Pfizer, Oct 2016, $14B | |
| Vital3D Technologies | Vilnius, Lithuania | Bioprinted tissues and organs |
| Abbott | Nepean, ON | Diagnostics |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| Next Science | Sydney, Australia | Anti-Biofilm Wound/Surgical Solutions |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| , | Acquired by Mallinckrodt, Aug 2014 $5.8B | |
| LabTwin | Berlin, Germany | AI-powered digital lab assistant |
| , | Renamed BakoDx, educational services and sales platform | |
| , | Dissolved | |
| CereHealth | Littleton, CO | Brain Imaging |
| , | Wound down Mar 2021 | |
| , | ||
| , | Website down Jun 2023 - Dec 2023 | |
| , | Shut down, Dec 2015; fka ChanRx | |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Verge Genomics | South SF, CA | Algorithm-based Drug Discovery |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| , | ||
| , | Acquired by Neopharm Labs, Nov 2016 | |
| , | Shut down Late 2020 | |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| , | Website down Mar 2023 - Dec 2023 | |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| , | Website down Jan 2019-Feb 2019 | |
| , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals | |
| , | Now go by AVEO Oncology | |
| Medelis | Ypres, Belgium | Clinical Research |
| Nimble Therapeutics | Madison, WI | Photoprotected Amino Acids |
| , | Liquidating, Jun 2021 | |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Changed to Biowest Pharmaceuticals Mar 2010 | |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| , | Website Down Dec 2022 - Mar 2023 | |
| , | Rolled into ImmunityBio | |
| , | Stopped reporting to SEC, shareholders suing in 2016 | |
| Pfizer | Ringaskiddy, Ireland | API production |
| , | Website down Aug 2024 - Jan 2025 | |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B | |
| , | Acquired by Cubist, Oct 2011, $415M | |
| TeraRecon | Durham, NC | Advanced image processing |
| , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 | |
| , | Website gone May 2021 | |
| , | Shut down Aug 2020 | |
| Anokion | Ecublens, Switzerland | Immune-tolerated therapeutic proteins |
| , | Acquired by Roche, Nov 2008 | |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| , | Acquired by Patrys, Aug 2016 | |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| , | ||
| MicroPort | Shanghai, China | Medical Devices |
| , | Folded into BioTissue | |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Alterity Therapeutics | Melbourne, Australia | Small Molecule |
| , | Acquired by Roche, Jan 2016, $115M + $420 Milestones | |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| , | Acquired by BBI, Mar 2018 | |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Zimmer Biomet | Warsaw, IN | Implants |
| , | Bankrupt, Oct 2017 | |
| Nuvig Therapeutics | Redwood City, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| , | Now Talon Therapeutics | |
| , | Bought by J&J, Mar 2015 | |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Pfizer | Hurley, UK | Consumer Healthcare |
| , | Assets acquired by Aridis Pharmaceuticals, May 2013 | |
| , | Gone 2005 | |
| , | Acquired by Solvias, Jul 2022 | |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| PartitionBio | Cambridge, UK | Biocondensate-based macromolecule delivery platform |
| , | Website down Dec 2024; LI page gone Jul 2024 | |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Shell company, trademark abandoned | |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Novotech | Taipei, Taiwan | Clinical Research |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| , | Website down Mar 2024 - Jul 2024 | |
| May Health | Paris, France | Ovulation Restoration Therapy |
| , | Acquired by Leo Pharma 2009 | |
| Roche | Schlieren, Switzerland | Small Molecules |
| , | Website not updated since 2009 as of Oct 2018 | |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen | |
| , | Acquired by Recro, Aug 2021 | |
| , | Liquidating, Feb 2024 | |
| Proteinea | Newton, MA | AI-Based protein Discovery |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| , | Changed name to Menlo Therapeutics, May 2016 | |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| , | Changed name to Progyny, Apr 2015 | |
| , | Shut Down pre-Apr 2017 | |
| , | Merged with Celldex | |
| , | Shut down May 2018 | |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Medrio | San Francisco, CA | Clinical Trial Software |
| , | Acquired by Eli Lilly, Dec 2023 | |
| , | Acquired by Boston Scientific, May 2014 | |
| , | Website down Dec 2023; Not registered in MA, Feb 2023 | |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| , | Renamed Crown Aesthetics | |
| , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 | |
| , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site | |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| , | Now named Sotera Wireless | |
| , | Changed Name to DelSite | |
| , | Renamed Gnome Sciences | |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| , | Renamed Porosome Therapeutics, Aug 2023 | |
| , | Renamed Azenta Life Sciences, Sep 2021 | |
| , | ||
| , | Closed | |
| CONMED | Utica, NY | Surgical, Medical Devices |
| , | Seems gone | |
| , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance | |
| Vertex | Boston, MA | Small Molecules |
| , | Acquired by Smith & Nephew, Jan 2020 | |
| Levolta Pharmaceuticals | Bethlehem, PA | Improved delivery |
| , | Brought into Precigen | |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| EnzyTag | Geleen, Netherlands | Small Molecule, Peptide Manufacturing Technology |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| , | Doesn't seem active, Apr 2023 | |
| , | Bought by BMS 2009 | |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| , | Acquired by MDS Analytical, Jun 2008, $13M | |
| Generare | Paris, France | Microbial DNA Drug Discovery Platform |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| , | Assets acquired by Labcorp | |
| , | Acquired by Amneal, May 2018 | |
| , | Website down Dec 2018 - Mar 2019 | |
| , | Website Gone, Oct 2016 | |
| , | Acquired by Premier Research, Jul 2018 | |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| , | Website down May 2023 - Dec 2023 | |
| , | No website Oct 2019 - May 2023 | |
| , | Assets purchased by Oxford Immunotec, Aug 2014 | |
| , | No news 2020 - Nov 2024 | |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| , | Now Dance Biopharm | |
| , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 | |
| , | Renamed PRACS Institute | |
| , | Bought by Cephalon, Jan 2009, $250M | |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| , | Renamed Pacira Biosciences, Mar 2019 | |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| , | Merged with Albireo, Oct 2016 | |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| , | ||
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| , | No info | |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| , | Merged with Kingbird, probably to get access to its ticker | |
| Nurix Therapeutics | San Francisco, CA | Small Molecules, Protein Degradation |
| , | Website hijacked, Dec 2024 | |
| , | Presumed gone; Website down Mar 2020 - Sep 2020 | |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| , | Acquired by Insightful Science, May 2020 | |
| Vitalunga | , | |
| , | Website down Oct 2022 - Feb 2023 | |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| , | Renamed Eliquent Life Sciences | |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Benchmark Research | Metairie, LA | Clinical Research |
| Accurant Biotech | Cranbury, NJ | CMC, Bioanalysis, Consulting |
| , | Shut down 2009 | |
| , | Bought by Pernix Mar 2013, Renamed Pernix Sleep | |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| The Micron Group | Overland Park, KS | Consulting |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| Perimed | Järfälla, Sweden | Vascular Imaging |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| , | Website down Aug 2023 - Dec 2023, no one at company | |
| , | Dissolved, Apr 2010 | |
| , | Merged with CANTABio Dec 2015 | |
| , | Renamed AilseBio, Nov 2024 | |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| , | Gone post 2014 | |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| , | No website Dec 2016-Dec 2018, Sole employee has many other jobs | |
| , | Now Venebio | |
| , | Acquired by Oxford Immunotec, Oct 2016 | |
| , | Gone 2019 | |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| , | Renamed Transcenta | |
| Lifebit | London, UK | Genetic Data Analysis |
| , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 | |
| , | Bought by BASF, Nov 2012, $844M | |
| , | Stock went to zero in 2012, Shell company | |
| Depixus | Paris, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| , | Website Down May 2024 - Dec 2024 | |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| , | ||
| , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma | |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| , | Acquired by Concordia Healthcare, Sep 2015 | |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| , | Renamed SPT Labtech | |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| , | Merged with Pluristyx, Oct 2022 | |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| , | Shut down July 2009 | |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| , | Acquired by Boston Scientific, Nov 2016, $210M | |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| , | Owns Thunderbolt Pharma, no website Apr 2019 | |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| , | Gone, pre-Jun 2016 | |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| , | Acquired by Roche, Sep 2020, $450M | |
| , | Shut down Mar 2024 | |
| , | Merged with NAYA Biosciences, Oct 2024 | |
| , | Website gone Nov 2019 | |
| , | Acquired by IQVIA | |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| , | Bought by Sandoz from Alcon Oct 2011 | |
| , | now CenExelCBH | |
| , | Acquired by ProPharma, Jul 2018 | |
| , | CEO/Sole Employee retired, Dec 2023 | |
| VoxCell BioInnovation | Victoria, BC | Model Tissue Platforms for Drug Discovery |
| , | Website gone, Dec 2019 | |
| , | Funding cut off, Apr 2017, shut down Aug 2017 | |
| , | Renamed Inspirna, Sep 2021 | |
| , | Gone Jul 2018 | |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| , | ||
| , | Renamed Nitrase Biosciences | |
| Applied Therapeutics | New York, NY | Small Molecules |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| , | Business registration canceled in VA | |
| , | Bought by ProMetic, Aug 2016, $34M | |
| Gennao Bio | Pennington, NJ | Nucleic Acid Therapeutic Delivery |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| MSD | Dublin, Ireland | Women's Health Products |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| , | Renamed PrintBio | |
| , | Bought by Zeiss, Jan 2014 | |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| , | Shut down, late 2023 | |
| , | Not registered in MA, Nov 2022 | |
| , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B | |
| MantraPharma | Lévis, QC | Generics |
| Paramit | Morgan Hill, CA | Medical Device and Life Science Instrument Product Development and Manufacturing |
| , | Renamed Argos Therapeutics | |
| , | Acquired by Dianthus, Sep 2023 | |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 | |
| , | Renamed CorVista Health, Dec 2020 | |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Naveris | Waltham, MA | Cancer Diagnostic |
| Getinge | Merrimack, NH | Medical Technology |
| , | Renamed Ehmet Health | |
| , | Acquired by Kriya Therapeutics, Jan 2022 | |
| Sebia | Lisses, France | Electrophoresis |
| , | Website not updated in five years, emails bounced | |
| , | Recombinant nanobodies | |
| , | Rebranded as SeaStar Medical, 2018 | |
| , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 | |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| 20/20 OptimEyes Technologies | Hamilton, ON | Mucosal Drug Delivery |
| , | Bought by Clinical Data, Aug 2008, $11M | |
| Abbott | Des Plaines, IL | Diagnostics |
| Engitix | London, UK | Human Organ Decellularization Technology |
| , | ||
| Navinta | Ewing, NJ | Generics |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Website Down Nov 2022 - Apr 2023 | |
| Aenova | Regensburg, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Bankrupt Nov 2022 | |
| , | Merged into Diversigen | |
| Cytiva | Marlborough, MA | Medical Devices |
| , | Website down Jul 2023 - Dec 2023 | |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| , | Acquired by Cellmid, May 2013 | |
| , | People left Mar 2019, Website down Jan 2020 - Feb 2020 | |
| |
Philadelphia, PA | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Ancient website ©2017, last news 2017 | |
| , | Acquired by Immunai, Mar 2021 | |
| , | 12 years nothing past RD, Residential Address, Nov 2021 | |
| , | Renamed Biolidics | |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| Zai Lab | Cambridge, MA | Small Molecules |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| , | Shut down 2011 | |
| Novotech | Melbourne, Australia | Clinical Research |
| , | Acquired by YM Biosciences, Oct 2009, $14M | |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Analiza | Cleveland, OH | Physicochemical Services |
| , | Bought by Eli Lilly, Feb 2019, $8B | |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| , | Acquired by Promise Proteomics, Jul 2019 | |
| Getinge | Englewood, CO | Medical Technology |
| Aurigene | Bangalore, India | Drug discovery |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Coral Drugs | New Delhi, India | APIs |
| , | Shut down Feb 2025 | |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| Ascle Therapeutics | , | No website Nov 2023 |
| , | Acquired by PharmaDrug, Feb 2021 | |
| , | Acquired by Ergomed, May 2016 | |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| , | Website down Oct 2019 - Dec 2019 | |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| , | Technology acquired by Q-State Biosciences, 2017 | |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| , | Bought by J&J | |
| TBG Diagnostics | Melbourne , Australia | Molecular Diagnostics |
| , | Renamed inVentiv Health Clinical | |
| , | Became real estate company | |
| , | Website Gone Jan 2018; Business Registration Delinquent | |
| , | Website gone, Mar 2018; business suspended by CA | |
| , | Dissolved Jul 2013 | |
| Polpharma Biologics | Utrecht, Netherlands | Biosimilars |
| , | Shut down Dec 2020 | |
| , | Acquired by Sterling Pharma | |
| , | Bankrupt, Jan 2024 | |
| , | Not registered as a business in MA Dec 2018 - Feb 2022 | |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Acquired by AE Biofuels 2011 | |
| , | Shut down 2015 | |
| , | Renamed Ralexar Therapeutics, Mar 2016 | |
| , | Merged with Genetics Research, Jul 2017 | |
| , | Renamed Exicure | |
| Proteintech | Wuhan, China | Research Antibodies |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| , | Merged with ImaBiotech, 2021 | |
| , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 | |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| , | Merged into Gilead, Mar 1999 | |
| , | Now part of Crescent Pharmaceuticals | |
| , | Merged with Intract Pharma, Oct 2024; fka Hillstream BioPharma | |
| Monobind | Lake Forest, CA | IVD |
| , | Renamed OneSource, Sep 2024 | |
| , | Website down Oct 2020 - Feb 2021 | |
| , | Shut Down Apr 2021 | |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| , | Bought by Integra LIfeSciences, Sep 2019 | |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| , | Acquired by Horizon Discovery, $48M, Sep 2014 | |
| Treeline Biosciences | San Diego, CA | Molecular targets in oncology that are validated but difficult to drug |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| , | Marked as closed on Google, Mar 2022 | |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Unicyte | Oberdorf , Switzerland | Stem Cell Therapeutics |
| XtalPi | Beijing, China | AI Drug Design |
| , | Gone | |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| , | Basically Gone | |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| , | Bankrupt May 2021 | |
| , | ||
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Alife | San Francisco, CA | AI-powered IVF |
| , | Shut down Dec 2015 | |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| , | Bought by Merck Animal Health, Nov 2015 | |
| , | Website down May 2024 - Dec 2024 | |
| , | Changed Name to Vicuron Pharmaceuticals | |
| Diagast | Loos, France | Transfusion Reagents |
| Grunenthal | Origgio, Italy | Small molecules |
| , | ||
| , | Acquired by Onset Dermatology | |
| , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 | |
| , | Website down Aug 2023 - Feb 2024 | |
| , | Website down Dec 2023 - May 2024 | |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| , | ||
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| , | Renamed 3Dispense | |
| , | SEC problems | |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones | |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| , | Now Sandoz | |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| , | Started a fintech investment arm, don't seem to do science anymore; Merged with Curetis, Apr 2020 | |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| , | Everyone seems gone Jan 2022 | |
| , | Gone 2016 | |
| , | Seems gone Jan 2022 | |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| , | No website Jul 2019 - May 2023; 2019 BIO attendee | |
| AbbVie | Waco, TX | Contract Manufacturing |
| , | Website down Aug 2022 - Jan 2023 | |
| , | Merged with Salarius Pharmaceuticals, Jul 2019, took name | |
| NeuroMetrix | Woburn, MA | Device Delivering Pain Relief |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| , | Shut down except as a shell, Jan 2020 | |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| , | No idea what they do, Nov 2018 - Dec 2024 | |
| , | Website down Feb 2021 - May 2021 | |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| , | Acquired by Vernalis | |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| , | ||
| , | Acquired by Geltex Pharmaceuticals | |
| , | Shut down Oct 2017 | |
| , | Changed name to Stoke Therapeutics, Mar 2017 | |
| , | ||
| , | Closed | |
| , | Acquired by Abbott, Sep 2023 | |
| Arraystar | Rockville, MD | Microarrays |
| Elutia | Roswell, GA | Drug-eluting biomatrix |
| , | Greer now responsible for all their products | |
| , | Renamed Urica Therapeutics | |
| , | Liquidating, Dec 2023 | |
| , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones | |
| , | Short-lived, not sure was ever serious | |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Bious Life | Kaunas, Lithuania | Cell Culture Scaffolds |
| , | Sold Assets, Shut down Aug 2017 | |
| , | Shut down | |
| Scancell | Oxford, UK | Cancer vaccine |
| , | Acquired by Zoll, Apr 2021 | |
| , | ||
| MAGBIO Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| , | Merged with Cbio to become Invion, Aug 2012 | |
| , | Bought by Amgen, Mar 2004, $1.3B | |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Verana Health | San Francisco, CA | Clinical Database |
| , | Renamed MdXHealth, Sep 2010 | |
| , | Renamed AlgoTx | |
| , | Acquired by EAG, 2011 | |
| , | Acquired by Curia, Jul 2021 | |
| , | ||
| , | Merged with Sorin, renamed LivaNova, Oct 2015 | |
| , | Acquired by PharmaLex | |
| , | Bankrupt Feb 2019 | |
| , | Acquired by Tempus, Feb 2022 | |
| , | Renamed Smithers, Sep 2019 | |
| Deciduous Therapeutics | San Francisco, CA | Medicines that activate the endogenous immune mechanism responsible for the elimination of senescent cells |
| , | Acquired by Fisher Diagnostics, Mar 2006 | |
| , | Website down Apr 2021 - Dec 2021 | |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| , | Renamed Enovis, Apr 2022 | |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| , | Website copyright 2009, seems defunct | |
| , | Renamed miniPCR | |
| , | Acquired by Ginkgo Bioworks, Jun 2022 | |
| , | Gone 2016 | |
| , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian | |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 | |
| , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX | |
| , | Website is 12 years old as of Dec 2019 | |
| , | Merged into General Oncology, Nov 2015 | |
| , | Renamed Juno Therapeutics, Oct 2013 | |
| , | Website down Sep 2024 - Feb 2025 | |
| NTC | Milan, Italy | Generics |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| , | Renamed Telesis Bio, Oct 2022 | |
| , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience | |
| , | Renamed IGY Life Sciences | |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| , | Assets acquired by Kanvas Biosciences, Oct 2023 | |
| , | Shutting down Jan 2023 | |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| , | Seems inactive, Feb 2025 | |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| , | Acquired by Medtronic, May 2021 | |
| , | Website Gone | |
| Labshire | Cambridge, MA | Laboratory Consulting |
| , | Acquired by Arbor Biotechnologies | |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| , | Merged into Wright Medical, Oct 2015 | |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| , | Merged with OmKure Therapeutics, Oct 2024 | |
| Wasdell Group | Newcastle, UK | Contract Manufacturing - nonsterile |
| , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 | |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Sensible Medical Innovations | Netanya, Israel | Lung Fluid Measurement for Heart Failure Patients |
| , | Shut down Mar 2024 | |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| , | Acquired by Chiron, 2000, $600M | |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| , | Bought by Teva Mar 2015, $3.2B | |
| , | Website down Oct 2024 - Feb 2025, closed on Google | |
| , | No news 2017-2023, can't find any registration info Nov 2023 | |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| , | Website down Aug 2022 - Jan 2023 | |
| Teclison | Taipei, Taiwan | Cancer Therapies |
| , | Acquired by Velocity Clinical Research | |
| , | Acquired by Abiomed, Apr 2020 | |
| , | Website down Jun 2024 - Sep 2024 | |
| Peptris Technologies Private | Bangalore, India | AI Protein tetris |
| Syneos Health | Princeton, NJ | Clinical Development |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| , | Stock worthless. Likely shell company. | |
| , | Renamed May Health, Sep 2022 | |
| , | Acquired by i2o Therapeutics, Aug 2023 | |
| , | Bankrupt, merged into HedgePath Pharmaceuticals | |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| , | Winding Down, Jul 2024 | |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Innocare | Nanjing, China | Cancer Treatments |
| , | Renamed ImmunogenX | |
| BioChain | Newark, CA | Sample Preparation |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. | |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| , | Website gone Jan 2020 | |
| BA Sciences | Morrisville, NC | Analytical Services |
| Aptamer Group | York, UK | Aptamer selection and development services |
| , | Acquired by Avalo Therapeutics, Mar 2024, $22M | |
| , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 | |
| , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones | |
| Frontera Therapeutics | Bedford, MA | Gene Therapy Development |
| , | Reverse merged with Adynxx, May 2019, took name | |
| , | Shut down Feb 2020 | |
| , | ||
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| , | Acquired by Janssen, Feb 2022 | |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| , | Renamed Baxano Surgical | |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Biogen | Cambridge, MA | Small Molecules, Biologics |
| , | Website gone Nov 2018, Everyone left company | |
| , | HiFiBio JV, No site Feb 2019 - Aug 2020 | |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| FerroptoCure | Tokyo, Japan | xCT inhibitors |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| , | Acquired by Viatris, Jan 2023 | |
| , | Gone | |
| RegCell | Osaka, Japan | T Reg Therapies |
| Implanet America | Martillac, France | Spinal and Knee Implants |
| , | Renamed WNDM Medical, Apr 2018 | |
| Molecular Loop | Woburn, MA | NGS Technology |
| , | Acquired by Veranex, Jun 2021 | |
| , | Website down Oct 2021 - Jul 2022 | |
| , | Possibly rolled into Praxis Precision Medicines | |
| , | Acquired by Vaxin, Feb 2015 | |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| , | Acquired by Nexelis, Jul 2020 | |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine | |
| Ergomed | Belgrade, Serbia | Clinical Research |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| , | Folded into Umbrella company, Sep 2008 | |
| , | Merged with BioreclamationIVT, Jul 2015 | |
| , | Renamed Boston Neurosciences, Jul 2018 | |
| , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 | |
| , | Acquired by Vyaire, Oct 2017 | |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| , | Website down Feb 2022 - Jul 2022 | |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| FYR Diagnostics | Missoula, MT | Blood-based Diagnostics |
| , | Acquired by Mundipharma, Oct 2018 | |
| , | Website down Oct 2020 - Apr 2021 | |
| , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 | |
| TVAX Biomedical | Olathe, KS | Targeted Cell-Based Immunotherapy |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Starkey | Eden Prairie, MN | Hearing Aids |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| , | Acquired by Thermo Fisher, Mar 2018 | |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| , | Gone Feb 2020 | |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| Function Oncology | San Diego, CA | CRISPR-based functional genomics platform |
| , | Acquired by Pano Therapeutics, Apr 2022 | |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| , | Website down Oct 2022 - Mar 2023 | |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| , | Acquired by Ethicon, Mar 2017 | |
| , | ||
| , | ||
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| , | Merged with Clinipace, Apr 2021 | |
| , | Renamed Lenz Therapeutics, Jun 2021 | |
| , | Website gone | |
| , | Acquired by Fujifilm Irvine Scientific, Mar 2022 | |
| Axplora | Mourenx, France | API manufacturing |
| , | Merged with CytoPharm | |
| , | Bought by Ipsen, Oct 2008 | |
| , | Website down Mar 2023 - Dec 2023 | |
| Sartar Therapeutics | Helsinki, Finland | Drug Repurposing & Reformulation |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| , | MN Business revoked, Mar 2004 | |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| , | Acquired by Mallinckrodt, Dec 2017, $42M | |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical | |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| , | Website Gone, Aug 2017, company still filing annual reports into 2019 | |
| , | Website hacked; No updates since 2011 | |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| , | Acquired by Eli Lilly, Mar 2007 | |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| Silence Therapeutics | Berlin, Germany | RNAi |
| , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex | |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| , | Acquired by MicroHeart, Sep 2001 | |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 | |
| , | Key Assets acquired by Prometera Biosciences, Apr 2016 | |
| , | Shut Down Oct 2021; fka DRP Biomedical | |
| , | ||
| Ambrx | La Jolla, CA | PEGylation |
| , | Acquired by Xoma, Apr 2024 | |
| , | Renamed Efferent Labs, May 2015 | |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Luye Pharma | Shanghai, China | Small Molecules |
| NanoString | Seattle, WA | Gene Expression Analysis Technology |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| , | Company founded 2009, never got into clinic as of 2020. No employees | |
| , | ||
| , | Bought by Agilent | |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| , | Shut down after May 2022 | |
| NextCure | Beltsville, MD | Immune Therapies |
| Panag Pharma | Halifax, NS | OTC Cannabinoids |
| Corza Medical | Westwood, MA | Surgical Devices |
| , | No website Apr 2014 | |
| , | Website down Mar 2021 - Jul 2021 | |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| , | Acquired by Dilon Technologies, Apr 2020 | |
| InfraReDx | Bedford , MA | Medical Devices |
| , | IP acquired by Circle33 | |
| , | Website down Feb 2020 - Oct 2020 | |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 | |
| , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 | |
| , | Bought by Stiefel | |
| Hesperos | Orlando, FL | Human-on-a-chip |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| , | Charged with fraud by SEC. Not sure this company is legit anymore | |
| , | Acquired by Fortis Life Sciences, Mar 2021 | |
| Mogling Bio | Cincinnati, OH | Stem Cell Rejuvenation by Cdc42 Inhibition |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| , | ||
| , | Dissolved, 1998 | |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| , | ||
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| , | Closed Dec 2017 | |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Regen BioPharma | La Mesa, CA | Regenerative Medicine, Cell Therapy, Small Molecule |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| , | Website down Jun 2024 - Nov 2024 | |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| ExploRNA Therapeutics | Warsaw, Poland | mRNA Therapies |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| , | Acquired by Bio-Reference Labs 2010 | |
| , | No info, Feb 2019 - Aug 2021 | |
| , | Changed name to Compass Therapeutics, Jun 2014 | |
| Dante Genomics | New York, NY | Whole Genome Sequencing, enabling exploration of health, nutrition, and genetic predispositions. |
| HCS Pharma | Loos, France | Cell Imaging Screening |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| , | No website/taken over Jan 2024 - Jul 2024 | |
| , | Website down Feb 2021 - Sep 2021 | |
| , | Dormant Jan 2017, Employees gone | |
| , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) | |
| , | Bought by Nano Terra | |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 | |
| Allucent | San Diego, CA | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Acenxion Biosystems | Kansas City, KS | Direct Detection of Microbes |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| , | Bought by King Pharmaceuticals, now part of Zoetis | |
| , | Renamed GSK, May 2022 | |
| , | Renamed Adare Pharma Solutions | |
| , | Website gone Feb 2024 | |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| , | Bought by LabCorp, May 2005 | |
| Immune Technology Corp | New York, NY | Virology research products |
| , | Website down Jul 2023 - Dec 2023 | |
| Vectura | Cambridge, UK | Inhalers |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis | |
| Avistone | Beijing, China | Precision Oncology |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| , | Website gone Oct 2022 | |
| , | Renamed Sciex | |
| , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 | |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| Fabric Genomics | Oakland, CA | Computational genomics |
| , | Shut down Apr 2022 | |
| , | fka Advent Pharmaceuticals; no info on whether active since name change | |
| , | ||
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Acquired by GRI Bio, Apr 2023 | |
| , | Had a grant in 2008. No info for a long time | |
| Acacia Pharma | Cambridge, UK | Small Molecules |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| , | ||
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| , | Acquired by Evolent Health, Oct 2016 | |
| , | Acquired by Spectranetics, May 2014, $230M+ | |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Eddingpharm | Shanghai, China | Bringing medicines to Chinese market |
| Spinafx Medical | Toronto, ON | Steroid Injection Device |
| , | Just buzzwords on website Dec 2016 - Dec 2020 | |
| Nanox | Petah Tikva, Israel | Digital X-Ray |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| , | Gone | |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| , | Acquired by Labcorp, Dec 2021 | |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| , | Presumed gone | |
| , | Acquired by Discovery Labs, Jul 1997 | |
| , | ||
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Website down Dec 2021 - Jul 2022 | |
| , | Renamed Kolon TissueGene, Mar 2018 | |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| , | Website down Jan 2023 - Jul 2023 | |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| , | Website gone Dec 2017, single employee on LinkedIn | |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical | |
| , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 | |
| , | Bought by ICON plc, May 2014 | |
| , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. | |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| , | Bought by Wockhardt, Feb 2013, €150M | |
| , | Website down Oct 2020 - Feb 2021 | |
| , | Website gone May 2019; Shell Company | |
| , | Acquired by Endo Pharmaceuticals, Dec 2020 | |
| Sutro Biopharma | San Carlos, CA | Biochemical Protein Synthesis Platform |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| , | Acquired by Pall, Mar 2014 | |
| , | Part of PRA Health Sciences | |
| , | Renamed Climb Bio, Oct 2024 | |
| , | Now Kadmon | |
| , | Renamed Kenai Therapeutics, Feb 2024 | |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| , | Acquired by AbCellera, Nov 2020, $90M | |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Quratis | Seoul, Korea | Vaccines |
| Sandoz | Schaftenau , Austria | Generics, Biosimilars |
| , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 | |
| , | Merged with CellGenEx to form Xcyte, Jan 1998 | |
| , | Acquired by 10X Genomics, Aug 2018 | |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| , | Website Down Feb 2025 | |
| , | Renamed RRD Biopharma Development, Feb 2024 | |
| , | Renamed Spexis, Dec 2021 | |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| , | Renamed Translate Bio, Jun 2017 | |
| , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 | |
| Charles River Laboratories | Rockville, MD | Fully integrated contract development and manufacturing organization with a focus on AAV, LVV, RVV, Adeno and others |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| , | Renamed Sandia Biotech | |
| Avacta Group | Wetherby, UK | Drug Development Platform |
| Regeneron | Basking Ridge, NJ | Small Molecules, Biologics |
| , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 | |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Wasdell Group | Swindon, UK | Contract Manufacturing - nonsterile |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Aadi Bioscience | Morristown, NJ | Cancer Therapies |
| , | Acquired by Bioventus, Oct 2021, $518M | |
| NeuroPointDx | Madison, WI | Autism Diagnosis |
| , | Shut down | |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| , | Website down Dec 2022 - Feb 2023 | |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| , | Acquired by Cipla, Jul 2014 | |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| , | Shut down Nov 2013 | |
| Emmetrope Ophthalmics | Menlo Park, CA | Magnetic Cell Delivery |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| , | Website down Oct 2021 - Jul 2022 | |
| , | Out of business Jul 2015 | |
| , | ||
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| , | Shut down Apr 2022 | |
| , | Acquired by NAYA Biosciences, Jan 2024, $20M | |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| Lupin | Mandideep, India | Generics |
| , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones | |
| , | Renamed ID Pharma, Apr 2015 | |
| Boston Scientific | Valencia, CA | Medical Devices |
| , | Founder and only main employee gone, Dec 2021 | |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| , | Renamed AcuraBio, Aug 2022 | |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| , | Website taken over, Nov 2016 | |
| , | Withdrawn Sep 2020 | |
| , | Bought by Ginkgo Bioworks, Jan 2017 | |
| , | Renamed DC Biosciences | |
| , | Acquired by LGC, Feb 2018 | |
| OncoPep | Cambridge, MA | Cancer vaccine |
| , | Renamed Lykos Therapeutics, Jan 2024 | |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| , | Website gone Feb 2017, no employees found anywhere | |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| SparingVision | Philadelphia, PA | Retinal Gene Therapy Treatments |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| , | Acquired by Aviva Systems, Feb 2017 | |
| , | Acquired by Arcturus, Sep 2017 via reverse merger | |
| GenomSys | Morges, Switzerland | Genomic Data Management |
| , | Acquired by AMEGA biotech, early 1990s | |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| , | Website down Apr 2023 - Sep 2023 | |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| , | Website down May 2021 - Oct 2021 | |
| , | ||
| , | Website down Apr 2024 - Aug 2024 | |
| , | Bought by Bio-rad | |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| , | Website down Jul 2024 - Dec 2024 | |
| , | Acquired by Omeros | |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| , | ||
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| , | Website down Sep 2023 - Mar 2024 | |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| , | ||
| , | Website gone, Mar 2017 | |
| , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 | |
| , | Employees all gone, Nov 2017 | |
| , | Website from 2008 as of Jun 2019, seems unserious | |
| , | Merged with OpGen, Feb 2021 | |
| , | Assets bought by GFBiochemicals, Feb 2016 | |
| , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen | |
| Diagnostic Robotics | Virtual, Virtual | AI-triage and clinical-predications platform |
| , | Changed name to Navitas Life Sciences, Jun 2017 | |
| , | Acquired by Agilent, Nov 2015 | |
| Applied StemCell | Milpitas, CA | Cell Lines, Transgenic Mice, Reagents, Lab Tools |
| , | Acquired by Servier, Jun 2020 | |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| , | Website down Jul 2019 - Oct 2019 | |
| , | ||
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| , | Acquired by BigHat Biosciences, Mar 2022 | |
| , | Bought by ViroLogics, Dec 2004, $160M | |
| , | Renamed Xeridiem, 2011 | |
| , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. | |
| , | Renamed Tioma Therapeutics, Aug 2016 | |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| ELITech Group | Puteaux, France | Clinical Testing Supplies |
| , | No news 2020 - Nov 2024 | |
| , | Acquired by Boston Scientific, Apr 2001, $8M | |
| , | Changed name to Precision Therapeutics, Jan 2018 | |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed | |
| , | Dissolved Jul 2018 | |
| Dilon Diagnostics | Newport News, VA | Probes, Imaging Devices |
| , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics | |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| , | Bankrupt, defunct 2010 | |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell | |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| , | Acquired by Transnetyx, Aug 2023 | |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| , | Bought by Coeptis Pharmaceuticals, Nov 2018 | |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| , | Renamed Celixir | |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Changed name to Lightpoint Medical, Jan 2013 | |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| , | Website gone, Jan 2019 | |
| , | Acquired by Schering, Mar 2002, $140M stock | |
| 7D Surgical | Toronto, ON | Image Guided Surgery System |
| , | Website Gone, Layoffs 2014 | |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| , | Website down Jan 2021 - May 2021 | |
| Lazuline Biotech | Hyderabad , India | Contract Biologics Manufacturing, Biosimilars |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| , | Sold product to Marina Biotech, Jun 2017 | |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| , | No info, Aug 2022 | |
| , | Rebranded as epicrispr, Aug 2024 | |
| Biolab Pharma | Mississauga, ON | Small Molecules |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Day Zero Diagnostics | Watertown, MA | Machine learning to determine antibiotic resistance from genomic data |
| , | Sold to PE 2005, unsure of fate | |
| , | Renamed Emtora Biosciences, Feb 2019 | |
| , | No info since 2013 as of Mar 2019, presumed inactive | |
| , | Acquired by Veristat, Oct 2018 | |
| , | Website down Jan 2019 - Jun 2019 | |
| , | Acquired by Thermo Fisher, Sep 2009, €330M | |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Neuros Medical | Aliso Viejo, CA | Neuromodulation Device |
| , | Acquired by Cofactor Genomics, Feb 2016 | |
| Wallaby Medical | Laguna Hills, CA | Cranial navigation, catheter |
| , | No news 2016 - Nov 2024 | |
| GENINUS | Seoul, Korea | Liquid Biopsy, Cancer Genomics |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| , | Website down Oct 2023 - Mar 2024 | |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Apicore | Gujarat, India | API Development & Manufacturing |
| , | Became Biogen Idec after merging with Biogen in 2003 | |
| , | Website taken over, Oct 2017 | |
| , | Not Active | |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| Diality | Irvine, CA | Hemodialysis System |
| , | Gone Jun 2019 | |
| , | Renamed Aarvik Therapeutics | |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| , | Changed name to Ischemix, 2006 | |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| , | Acquired by Ligand Pharmaceuticals 2008 | |
| , | ||
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| , | Acquired by Quotient Sciences, Nov 2017 | |
| , | ||
| , | Shut down Apr 2024 | |
| , | Acquired by Integrated DNA Technologies, Jun 2016 | |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Rebranded as Envigo, 2015 | |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| , | Acquired by Dechra, Mar 2016 | |
| , | Acquired by Steris, Nov 2015 | |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Recipharm | Parets, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Acquired by Medtronic, Jan 2009, $225M | |
| , | Renamed Processa Pharmaceuticals, Oct 2017 | |
| , | Renamed Lung Biotechnology | |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| , | ||
| , | Acquired by Merck, Jun 2019, up to $773M | |
| , | No info since 2013 as of 2021, not registered in CA | |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| , | Renamed Coave Therapeutics, Jul 2021 | |
| Ichnos Glenmark Innovation | Epalinges, Switzerland | Bispecific Antibodies |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| , | Acquired by Repligen, Apr 2016, $9.1M cash + stock | |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx | |
| RNAnalytics | Neulengbach, Austria | Analysis methods for lipid nanoparticles |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| , | Renamed Contraria Biotech, Jun 2024 | |
| , | Acquired by Axonics, Feb 2021, $200M | |
| , | Part of Bausch Health; fka Valeant Dermatology | |
| Aran Biomedical | Galway, Ireland | Custom Design, Development & Manufacturing of Medical Implants - Medical Fabrics, Coating and PTFE Encapsulation |
| , | Renamed Purple Biotech, Dec 2020 | |
| , | No website, Dec 2018 - Dec 2020 | |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| , | Acquired by Emalex Biosciences, Aug 2018 | |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| , | Acquired by LEXEO Therapeutics, Jul 2021 | |
| , | Website down Feb 2024 - Oct 2024 | |
| , | Website gone, Jul 2015 | |
| , | Acquired by Biolex May 2004 | |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| , | Website Gone Oct 2016 | |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Exactech | Gainesville, FL | Medical Implants |
| |
Nottingham, UK | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| , | Acquired by Sanofi, Apr 2023, $2.9B | |
| , | Acquired by Vir Biotechnology, Jan 2017 | |
| , | Merged with Biosearch Technologies, 2013 | |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones | |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| , | Acquired by Varian, May 2019 | |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| , | Renamed Icemi Pharmaceutical, May 2016 | |
| , | ||
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| , | ||
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| , | Bought by Bruker, Feb 2011, | |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 | |
| , | Bought by Medtronic, Jan 2019, $316M | |
| , | Bankrupt | |
| , | Acquired by Acerus, Mar 2022 | |
| , | Presumed gone. Listing employees on website in 2018 who left in 2011 | |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| , | Owned by Eurofins | |
| , | Renamed Terra Bioworks, Oct 2022 | |
| , | Acquired by Medtronic, Nov 2020 | |
| , | Bought by Amgen 2007 | |
| , | Gone, no info | |
| Cosmo Pharmaceuticals | Dublin, Ireland | Specialty pharmaceuticals |
| Curadev | Kent, UK | Immuno-oncology |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Graviton Bioscience | New York, NY | Therapies that inhibit Rho/Rho-associated coiled-coil containing protein kinase 2 |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| , | Rebranded as BA Sciences, Jan 2024 | |
| , | ||
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| MilliporeSigma | Madison, WI | Small Molecules |
| , | Gone | |
| , | Acquired by Biomet, Nov 2013, $150M | |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| Nanosonics | Manchester, UK | Ultrasound |
| Haemonetics | Boston, MA | Blood Management Solutions |
| , | Website gone Jan 2019 | |
| Merck KGaA | Singapore, Singapore | |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M | |
| Stilla Technologies | Villejuif, France | Digital PCR Technology |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| Ottobock | Königsee, Germany | Prosthetics |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 | |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| , | Employees all gone except CEO, Apr 2022 | |
| , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto | |
| , | Now known as VBI Vaccines | |
| , | Acquired by Excelra, Apr 2023 | |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| , | Shut Down, Jan 2018 | |
| Sterifre Medical | Kirkland, WA | Sterilization Technology |
| HiberCell | Boston, MA | Tumor dormancy detection and treatments |
| MedGyn Products | Westmont, IL | OBG Devices |
| ProAbtech | Gwangju, Korea | Conjugation Chemistry for Biologics |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| , | Acquired by LabCorp, Jun 2001 | |
| , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 | |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Lavipharm | Paris, France | Small molecules |
| , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 | |
| , | Dissolved Jan 2024, per CEO linkedin post | |
| Visby Medical | San Jose, CA | Diagnostics |
| Genuine Biosystem | Chennai, India | IVD Products |
| , | Acquired by Lundbeck, Nov 2002 | |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| , | ||
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| , | Assets acquired by Patrys, Oct 2008 | |
| , | Renamed Seeker Biologics | |
| , | Renamed Verily, Dec 2015 | |
| Canopy Biosciences | St. Louis, MO | Gene Editing, Gene Expression, Bioprocessing |
| , | Website down Dec 2020 - Jan 2021 | |
| , | Shut down Mar 2023 | |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| , | Website gone 2-27-15, company is old | |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| , | Acquired by Sinensis Life Sciences, Oct 2014 | |
| , | Renamed AliveDx, Jul 2023 | |
| , | Program Acquired by Telix, Jan 2017 | |
| , | Assets sold off Feb 2008 | |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| , | Website down Jun 2020 - Feb 2021 | |
| Devsynthesis | Hyderbad, India | Chemistry CRO |
| , | Merged into Jena, Jul 2014 | |
| , | Liquidating Fall 2019 | |
| , | Closed 2017 | |
| , | Sold primary asset to Monopar Therapeutics, Nov 2017 | |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| , | Website down Aug 2024 - Feb 2025; fka GPB Scientific | |
| Sharp | Hamont-Achel, Belgium | Contract clinical trial services and commercial packaging services |
| , | Bought by Jubilant 2008 | |
| , | Shut down 2019 | |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| , | Acquired by Evolva, Sep 2009 | |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| , | Acquired by Corium, 2007 | |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| , | ||
| , | Tech sold Jun 2015 | |
| HilleVax | Boston, MA | Norovirus Vaccine |
| , | Website down Dec 2022 - Apr 2023 | |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Homepage not working, Jun 2019 | |
| Menarini | Firenze, Italy | Small Molecules |
| , | Sold for cryptocurrency ticker use | |
| , | Website Gone, President has new job | |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| , | Website gone Jun 2020, stock close to worthless | |
| , | Shut down Apr 2020 | |
| , | Acquired by Analogic, Mar 2013, $83M | |
| , | Changed name to Tribute Pharmaceuticals Jan 2013 | |
| , | Merged with Amneal, May 2018 | |
| , | CEO left Dec 2020 seems like only academic founder is left, location is a residence | |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| ICON plc. | Farmingdale, NY | Clinical Research |
| , | Merged with Peptonic, late 2023 | |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| , | Website gone Jun 2016 | |
| , | Website down Jan 2023 - Jul 2023 | |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 | |
| , | Renamed Curi Bio, Jul 2020 | |
| , | Presumed gone | |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| , | Website under construction Jul 2023 - Dec 2023; fka Bioven | |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| , | Website down Jun 2024; fka Kayem Pharmaceutical | |
| , | Bought by oracle | |
| , | Shut down 2019 | |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| Abbott | Altavista, VA | Nutrition |
| , | Dissolved Jan 2017 | |
| , | Acquired by Hetero Labs, Jan 2019 | |
| Genfit | Cambridge, MA | Drug Discovery |
| Santen | Tampere, Finland | Ophthalmics |
| , | Acquired by Illumina, Jul 2010 | |
| , | Renamed Kazia Therapeutics, Nov 2017 | |
| TreeFrog Therapeutics | Tokyo, Japan | 3D Stem Cell Culture Technology |
| |
King of Prussia, PA | WuXi Biologics is a biologics & vaccines CRDMO for antibodies, ADCs, recombinant proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| Bioptimus | Paris, France | AI Drug Discovery |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| SVA | Madison, WI | Biotechnology Management Consulting |
| Mediso | Budapest, Hungary | Medical Imaging |
| , | Merged with Sandoz to create Novartis | |
| Crown Bioscience | Taipei, Taiwan | Drug Development |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| Consilient Health | Surrey, UK | Small Molecules, Generics |
| , | Acquired by 10X Genomics, Oct 2020 | |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| , | Renamed Lyra Therapeutics, Sep 2018 | |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| , | Acquired by Integra LifeSciences, Jul 2019 | |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| , | ||
| , | ||
| , | Shut down May 2024 | |
| |
Taipei, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| , | Website down May 2023 - Dec 2023 | |
| , | Renamed ProterixBio, Apr 2016 | |
| , | ||
| Transplant Genomics | Framingham, MA | Monitoring to prevent transplant rejection |
| , | Merged with BioAnalytix, Apr 2019 | |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Areterna | Gaithersburg, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Galapagos | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| , | Acquired by Roche, Dec 2014 | |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| , | Acquired by BioIVT, Mar 2018 | |
| , | Acquired, 2022 | |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| , | Website taken over by pharmacy spam, Jan 2020 | |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Restech | Houston, TX | Minimally invasive solutions for reflux disorders |
| , | Now Mercury Pharmaceuticals | |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| , | Liquidated, Dec 2019 | |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| , | Merged with Decade Sunshine, 2013 | |
| , | Reported closed prior to Oct 2013 | |
| , | Became Diaxonhit after Exonhit/In Gen Bio merger | |
| , | Gone 2019 | |
| , | Acquired by Compass Therapeutics, Jun 2021, $50M | |
| , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 | |
| , | Sold | |
| |
Nottingham, UK | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Failed, tried to come back, not sure of status | |
| , | Acquired by Symetis, technology moved to Polares Medical | |
| , | Bought by OncoResponse, Nov 2017 | |
| , | Acquired by Charles River, Jan 2018, £15M | |
| , | Acquired by Forest Labs, Apr 2014 | |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire | |
| , | Renamed EMulate Therapeutics, Mar 2019 | |
| Akttyva Therapeutics | Mansfield, MA | AI-based Drug Discovery |
| , | Ceased operating, Jul 2016 | |
| , | Merged into Decode Health | |
| , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 | |
| , | Shut down 2019 | |
| , | Acquired by Brooks, Nov 2016 | |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| , | CA business filings late, Jan 2022 - Jan 2025 | |
| , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals | |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| , | Website down May 2021 - Sep 2021 | |
| , | Acquired by CooperSurgical, Feb 2021 | |
| , | Renamed Montai Therapeutics, Apr 2024 | |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| , | Acquired by Pace Analytical, Jul 2021 | |
| , | Acquired by JSR Life Sciences, Mar 2021 | |
| , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics | |
| , | Renamed Polaris Genomics | |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| , | Acquired by Indivior, Mar 2023, $145M | |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| , | Acquired by Sartorius, Dec 2019, $50M | |
| DermBiont | Boston, MA | Topical Bacterial Products |
| , | Merged with Axol Bioscience, Mar 2021 | |
| , | Acquired by Ensoma, Feb 2023 | |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health | |
| , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 | |
| Arecor | Little Chesterford, UK | Formulation Technology |
| , | Website down Sep 2021 - Feb 2022 | |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| , | Acquired by Element Biosciences, Feb 2022 | |
| Instylla | Bedford, MA | Embolization treatment |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| , | Closed Feb 2005 | |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| , | Changed name to Opthea, Dec 2015 | |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| , | ||
| M3 Wake Research | Encino, CA | Clinical Research |
| , | Renamed Clever Culture Systems, Nov 2024 | |
| , | Russian vaccine maker, no website Aug 2019 - May 2023 | |
| , | Renamed MFX | |
| , | ||
| , | Now Hookipa Pharma | |
| , | Defunct | |
| , | No website Dec 2018 - Aug 2021; No news since 2015 | |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| , | Acquired by Cytiva, Oct 2022 | |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| , | Merging with private payroll company, Aug 2024 | |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| , | Website down Jan 2021 - May 2021 | |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 | |
| , | Shut down Feb 2024 | |
| , | Gone 2014 | |
| , | Shut down Mar 2019 | |
| , | Gone | |
| , | Shut down Oct 2020 | |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| , | Merged with hC Bioscience, Jan 2023 | |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Abbott | Donegal, Ireland | Diagnostics |
| , | Bought by Amgen 2006 | |
| , | Website gone, Dec 2015 | |
| , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne | |
| , | Acquired by Centocor Jun 2010 | |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| , | Website down Nov 2023 - Mar 2024 | |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| ALZpath | Carlsbad, CA | Alzheimer's Diagnostic |
| , | Website down Jul 2021 - Dec 2021 | |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| , | Shut down Oct 2022 | |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| , | Bankrupt Feb 2012 | |
| , | Changed name to Medisun Precision Medicine, Jun 2017 | |
| , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M | |
| , | Academic startup, no real progress from 2016-2022 | |
| , | Acquired by Evotec, Jul 2019, up to $90M | |
| , | No website Feb 2021 - May 2023; Canada based | |
| , | Assets acquired by Stryker, Sep 2016 | |
| , | ||
| Evosep | Odense, Denmark | Automated Sample Prep |
| , | Owned by Ranbaxy, then Sun Pharma | |
| , | Gone Jul 2022 | |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| , | Renamed Cresilon, Sep 2016 | |
| , | Seems to be shut down 2019; website gone Jan 2021 | |
| , | ||
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M | |
| Quanticate | Bangalore, India | Clinical Research |
| , | Changed name to Trividia Health, Jan 2016 | |
| , | Renamed ChitogenX, Sep 2022 | |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| , | Acquired by Avista Pharma, Jan 2018 | |
| , | Acquired by Evonik Jun 2016; fka Northern lipids | |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| , | Website down Apr 2022 - Jul 2022; aka Nanogap | |
| BioMap | Palo Alto, CA | AI Models |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| , | Acquired by iuvo BioScience, Jul 2018 | |
| , | Acquired by DNA2.0, Apr 2016, | |
| , | Moved to Mountain View, Site down May 2017, presume gone | |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 | |
| , | Website down Feb 2021 - Sep 2021 | |
| , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 | |
| , | ||
| Arzeda | Seattle, WA | Computation protein design |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| , | Acquired by Novo Nordisk, Dec 2020, $1.8B | |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| DermaRite | North Bergen, NJ | Foam Dressing |
| , | Bought by Wockhardt, May 2007, $265M | |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| , | Employees have other, more important jobs or have left and remain on website Feb 2020 | |
| , | Merged with Dovetail Genomics to become Cantata Bio | |
| PharmaLex | Bad Homburg vor der Höhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Merged with Synergy Pharmaceuticals, Jan 13 | |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| , | Acquired by Philips, Aug 2017, $1.9B | |
| , | Merged with Korro Bio, Nov 2023 | |
| Evonik Industries | Essen, Germany | API Manufacturing |
| , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M | |
| , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products | |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| , | Website down Feb 2024 - Jul 2024 | |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Minakem | Dunkerque , France | API Manufacturing |
| , | Acquired by Bayer, Mar 2014 | |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| , | Renamed Nura Bio, Apr 2020 | |
| , | Website down Dec 2020 - May 2021 | |
| , | Website down Oct 2022 - Mar 2023 | |
| ProPharma Group | San Diego, CA | Consulting |
| , | ||
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| , | ||
| Helsinn | Biasca, Switzerland | Small Molecules |
| , | Renamed Theonys, Aug 2021 | |
| , | Acquired by APIS Assay Technologies, Sep 2020 | |
| , | Website down Oct 2021 - Feb 2022 | |
| , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 | |
| , | Bankruptcy | |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| , | Now Myrexis | |
| , | Renamed NKGEN Biotech | |
| , | Bought by Philips, Mar 2008, $5.1B | |
| , | ||
| , | Acquired by kemPharm, May 2022, $7.6M | |
| , | ||
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| , | ||
| Pharos iBT | Anyang-si, Korea | AI Drug Development |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 | |
| , | Seems gone, Jun 2019 | |
| Healx | Cambridge, UK | AI Drug Discovery |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| , | Gone 2017 | |
| Aurigene | Kuala Lumpur, Malaysia | Drug discovery |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| , | Renamed Aera Therapeutics, Jul 2022 | |
| , | Closed down 2003, out of cash | |
| , | ||
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Criterium | Saratoga Springs, NY | Clinical Research |
| , | Acquired by Eurofins, Mar 2016 | |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| |
Basel, Switzerland | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| , | Acquired by Reliable HealthCare Logistics | |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| The Micron Group | Cambridge , UK | Consulting |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| , | Website down Nov 2022 - Mar 2023 | |
| , | Obesity Treatment | |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| , | Renamed Accuryn, Feb 2024 | |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Owlstone Medical | Darien, CT | Breath-based Diagnostics |
| Dexcom | San Diego, CA | Glucose Monitors |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| , | Turned into commercial website for weight loss | |
| , | ||
| , | Bought by Sanofi, Dec 2009, $1.9B | |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| , | Website password protected, Dec 2019 - Mar 2020 | |
| , | Acquired by Estee Lauder, Sep 2008 | |
| , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 | |
| , | CEO moved, Website is single page, Google says closed, Jan 2022 | |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Recipharm | Queenborough, UK | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Gone 2021 | |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| , | Seems abandoned, Apr 2018, Site gone | |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| ADMA Biologics | Ramsey, NJ | Biologics |
| , | Website down Jan 2024 - Aug 2024 | |
| Forecyte Bio | Shanghai, China | Cell , Gene Therapy CDMO |
| , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 | |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| , | ||
| , | Acquired by Sosei Group, Feb 2015 | |
| , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 | |
| , | ||
| Empatica | Milan, Italy | Seizure Detection |
| , | Renamed Signifier Medical Technologies | |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| , | Website down Dec 2019 - May 2020 | |
| Meissner | Castlebar, Ireland | Lab Systems |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| , | Acquired by Kowa, Sep 2008 | |
| Journey Colab | San Francisco, CA | Psychedelics, Mescaline |
| , | Website gone, Dec 2019 | |
| , | Acquired by Immusoft, Mar 2016 | |
| , | Acquired by Ignyta May 2013 | |
| , | Website down Dec 2022 - Apr 2023 | |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| KCR | Warsaw, Poland | Clinical Trials |
| , | Renamed Hycor BioMedical | |
| , | Renamed Astrea Bioseparations | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Shut Down, 2013 | |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| , | Supposed CEO sent crying emoji when we asked if company was still active | |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| ReproNovo | Lausanne, Switzerland | Reproduction Assistance Treatments |
| Singular Genomics | San Diego, CA | Genomics |
| , | Abbott acquired product, 2012 | |
| , | Acquired by Pharmakure, Apr 2021 | |
| , | Renamed LigoChem Biosciences, May 2024 | |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 | |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| , | Acquired by Coloplast, Oct 2020, $145M | |
| , | Website not working May 2021 - Sep 2021 | |
| , | Renamed Gensaic, Sep 2022 | |
| Inventiva | Daix, France | Small Molecules |
| , | Website down Sep 2022 - Feb 2023 | |
| , | ||
| , | Acquired by Ellab, Nov 2022 | |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| , | Acquired by LivaNova, Jul 2022 | |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| , | Website down Oct 2021 - Feb 2022 | |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| , | ||
| , | Website down Sep 2022 - Feb 2023 | |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| MicroGenDX | Lubboick, TX | Molecular Diagnostics, Sequencing |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| , | Renamed Actuate Therapeutics, Feb 2017? | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Acquired by Invitae, Aug 2017 | |
| , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here | |
| , | Bought by Perkin Elmer, Sep 2011, $600M | |
| , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 | |
| |
South Haven, MI | Grace Fine Chemical | U.S. Domestic CDMO offering process scaleup and commercialization of small molecule APIs, RSMs and intermediates. Network of 2 fully integrated sites with a world class analytical team offers an industry-leading flexible supply chain through the back integration of its intermediates. |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Covaris | Woburn, MA | DNA Sample Prep |
| , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo | |
| , | Website down Nov 2022 - Mar 2023 | |
| , | Renamed MedBiome | |
| , | Absorbed into Bavarian Nordic, 2010? | |
| , | Seems to have been rolled into Vascular Biosciences | |
| Lyndra Therapeutics | Watertown, MA | Drug Delivery |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Website gone, Aug-Oct 2017 | |
| , | Acquired by ViroPro, 2010 | |
| , | Website down Feb 2021 - Sep 2021 | |
| , | ||
| , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 | |
| , | Rebranded as EnnoDC | |
| , | Liquidated | |
| , | Terminated lease on HQ. Effectively done, Nov 2016 | |
| , | Seems defunct, employees gone | |
| , | Renamed Dextera Surgical, Jun 2016 | |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| Imcyse | Liège, Belgium | Immunotherapies, Synthetic Peptides |
| Primex Pharmaceuticals | Zug, Switzerland | Intravenous products |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| , | Website Gone Dec 2013 | |
| , | Bought by Millipore, Nov 2012 | |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | ||
| , | Ancient Website Nov 2019, last updated in 2006, presumed defunct | |
| Niche Generics | Arlesey, UK | Contract Generics |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| , | Bankrupt, Dec 2017 | |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| , | Website gone Oct 2019 | |
| , | Never filed business documents after founding in 2020 - 2023 | |
| , | Acquired by Sygnature Discovery, Oct 2020 | |
| , | Shut down Dec 2020 | |
| , | Website down Feb 2021 - Jun 2021 | |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| Vanessa Biotech | Navarre, Spain | Treatments for underserved populations |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| , | Founder gone | |
| Court Square Group | Springfield, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| , | Acquired by Angelini Pharma, Jan 2021 | |
| , | ||
| , | Acquired by Heat Biologics, Apr 2022 | |
| Texcell | Frederick, MD | Contract Research |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 | |
| , | Owner transitioned to real estate | |
| , | Insolvent, 2016 | |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| , | Acquired by Allergan, 2011 | |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| , | No longer active, Aug 2020 | |
| , | Website down Jul 2021 - Nov 2021 | |
| , | ||
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| , | Renamed CYduct Diagnostics, Dec 2020 | |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Siemens Healthineers | Forchheim, Germany | Medical Device Group |
| , | Gone. President had no scientific background. 'Founder' was a freshmen in college | |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| Restem | Corona, CA | Stem Cells |
| , | Acquired by Biocodex, Jun 2023 | |
| , | Acquired by Catalent, Oct 2014 | |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis | |
| , | Acquired by Zimmer, Sep 2019 | |
| , | Website Gone, scammy sites with similar name | |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| , | ||
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| , | Rebranded as Kadmon | |
| KalVista Pharmaceuticals | Cambridge, MA | Ophthalmology Products |
| , | ||
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Pharmanovia | London, UK | Acquisition of Drugs |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| , | Website down Feb 2024 - Jul 2024 | |
| Optimapharm | Zagreb, Croatia | Clinical Research Organization |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| , | renamed Locate Bio, Oct 2018 | |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| , | Renamed Cloud Pharmaceuticals, Jun 2014 | |
| , | Acquired by Gilead, 2003, $464M | |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| , | Acquired by Spectrum Solutions, Mar 2023 | |
| , | Seems gone | |
| , | Bankrupt, Shut Down Jul 2009 | |
| , | Renamed Strata Skin Sciences, Dec 2015 | |
| , | ||
| , | ||
| , | Bought by Medicis | |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Acquired by BASi, Jun 2002? | |
| Khloris Biosciences | San Jose, CA | Cancer Vaccine |
| , | Website Taken Over | |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Johnson and Johnson | Skillman, NJ | Consumer Products |
| , | Acquired by Olympus, Dec 2020, $340M | |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| , | Assets bought by The Genetics Company, Jun 2003 | |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Sampled | Piscataway, NJ | Biostorage |
| Pace Analytical | St. Rose, LA | Analytical Testing |
| Embody | Norfolk, VA | Soft Tissue Healing |
| , | GSK spinout, bought by Intarcia, Sep 2015 | |
| , | Renamed Kemp Proteins, Mar 2019 | |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| , | Website gone, Oct 2017 | |
| FineHeart | Pessac, France | Heart Failure Device |
| , | Website down Oct 2023 - Mar 2024 | |
| , | Bought by Circassia, Jun 2015, $158M | |
| , | Acquired by Pacific Biomarkers, Jun 2019 | |
| , | Assets acquired by Debiopharm, Feb 2014 | |
| , | Website down Apr 2022 - Jul 2022 | |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Bioneeds | Bangalore , India | Contract Research |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| , | Website down Jan 2023 - Sep 2023 | |
| , | Acquired by Liminal BioSciences, Jul 2020 | |
| , | ||
| , | Bought by J&J, now Part of Janssen Diagnostics | |
| Resilience | Mississauga, ON | Biomanufacturing |
| , | Merged into Cardea Oct 2019 | |
| GenomSys | Lugano, Switzerland | Genomic Data Management |
| , | Gone, 2018 | |
| , | Renamed G6 Spine | |
| Prominex | San Diego, CA | POC Diagnostics |
| , | ||
| , | Marked as closed on Google, Dec 2019 | |
| , | Renamed Arrowhead Pharmaceuticals | |
| , | Renamed Marengo Therapeutics, Feb 2021 | |
| Apicore | Somerset, NJ | API Development & Manufacturing |
| , | Merged with Mithridon, Jun 2008 | |
| August Bioservices | Nashville, TN | Research & Development Services |
| , | Acquired by Biocare Medical, Mar 2015 | |
| , | Renamed IGM Biosciences | |
| , | Product being sold by another company | |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| |
Beijing, China | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| , | Shut down Apr 2019 | |
| , | Acquired by Pernix Jan 2012 | |
| , | Website down Sep 2022 - Feb 2023 | |
| Synairgen | Southampton, UK | Inhaled Biologics |
| , | Bankrupt Apr 2013 | |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| , | Linkedin gone, website down Jul 2024 | |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Accellacare | Ames, IA | Clinical Research |
| , | Shut down Aug 2024 | |
| , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Renamed Spyre Therapeutics, Nov 2023 | |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| , | ||
| , | ||
| Triumvira Immunologics | Hamilton, ON | Adoptive Immunotherapy |
| Predicine | Hayward, CA | Liquid Biopsy |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| , | Website down Aug 2024 - Feb 2025 | |
| Silence Therapeutics | London, UK | RNAi |
| , | Acquired by UCB, Apr 2018, up to $30M | |
| , | Merged with Nanox, Nov 2021 | |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| , | Website gone Jan 2020 | |
| , | Gone Nov 2015 | |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 | |
| Akron Biotechnology | Sarasota, FL | Sera & Reagents |
| , | Acquired by Altasciences | |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Bolt Medical | Carlsbad, CA | Intravascular Lithotripsy |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| , | Acquired by Sorrento Therapeutics, Dec 2013 | |
| Coriolis Pharma | Martinsried, Germany | Biologics Contracting |
| , | ||
| , | Now just Berg | |
| , | Acquired by Adragos Pharma, Nov 2024 | |
| , | Renamed Predictive Oncology, Jun 2019 | |
| , | Website down Apr 2023 - Sep 2023 | |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| , | Renamed Overland Therapeutics, May 2024 | |
| L.E.A.F. Pharmaceuticals | Woburn, MA | Re-Engineering Existing Molecules |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| , | Acquired by Stryker, Jan 2025 | |
| , | Website down Oct 2021 - Mar 2022 | |
| , | Website gone Nov 2022 | |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| , | Website gone Dec 2019 - Aug 2021 | |
| CStone Pharmaceuticals | Beijing , China | Immuno-Oncology |
| , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 | |
| , | Gone | |
| , | ||
| , | Shut down Feb 2011 | |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Santen | Osaka, Japan | Ophthalmics |
| , | Bought by Pfizer, Oct 2010, $3.6B | |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| , | ||
| , | Acquired by Innoser, Jan 2023 | |
| , | Gone Sep 2018 | |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Axbio | Santa Clara, CA | Biochips |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Bought by Pfizer Feb 2000 $90B | |
| , | Bought by Baxter, Jul 2017 | |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| , | Acquired by Inscripta, Jan 2023 | |
| , | Website down Jul 2023 - Dec 2023 | |
| , | Shut Down Jun 2014 | |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| , | Website down Jan 2023 - Jul 2023 | |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| , | Website Down May 2024 - Nov 2024 | |
| , | Website gone Mar 2018 | |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| , | Website Gone | |
| Calico | South SF, CA | Aging treatments |
| , | Renamed Tavanta Therapeutics, Sep 2020 | |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| , | ||
| , | Changed named to Kodiak Sciences | |
| , | Now part of Uniogen, Jan 2022 | |
| , | Renamed MediPrint Ophthalmics, Jan 2021 | |
| , | ||
| Claris Bio | Jersey City, NJ | Corneal disease therapies |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| Abiologics | Cambridge, MA | Synteins |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| , | Website gone Nov 2019 | |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| , | Renamed BlueSphere Bio | |
| |
Emeryville, CA | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Olio Labs | , CA | AI Combination Products |
| , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 | |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones | |
| , | Website gone Feb 2023 | |
| , | ||
| , | Technically exists, one employee, Dec 2020 | |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| , | ||
| , | Acquired by Pyxis Oncology, Aug 2023, $16M | |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| , | Website gone Sep 2022 | |
| , | Website down Apr 2024 - Aug 2024 | |
| Novick Biosciences | Hyderabad, India | Contract Drug Discovery, Formulations |
| , | Gone pre-2011 | |
| , | Bought by HemCon, 2008 | |
| , | Acquired by Oracle, Jun 2022; fka Kantar Health | |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Shut down 2020 | |
| Westat | Rockville, MD | Clinical trial design, management, services |
| |
East Chicago, IN | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Stryker | Flower Mound, TX | Medical Devices |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| , | Website down Jan 2021 - Jul 2021; fka Virion Health | |
| , | Basically Gone Apr 2019 | |
| , | Website gone, marked as closed on google, emails bouncing | |
| , | Now Nexcyon Pharmaceuticals | |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| , | Website down Oct 2022 - Mar 2023 | |
| 3P Biopharmaceuticals | Navarra, Spain | Manufacturing & Services |
| , | Renamed Gatehouse Bio, 2019(?) | |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| , | Gone? | |
| , | Website down Apr 2022 - Aug 2022 | |
| AstraZeneca | Sodertalje , Sweden | Small Molecules, Vaccines, Biologics |
| Complete Genomics | San Jose, CA | Genomic Studies |
| , | Assets Acquired by Transposon Therapeutics, Nov 2024 | |
| , | Acquired by CooperSurgical, Jan 2019 | |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| , | Merged with Pharmalex, Nov 2017 | |
| Etna Biotech | Catania, Italy | Vaccine Technology |
| Taconic Biosciences | San Diego, CA | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Azzur | Waltham, MA | Consulting |
| , | Acquired by Perrigo, Mar 2015 | |
| Aginko Research | Marly, Switzerland | Musculosketal Clinical Services |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| , | Merged with Immune Pharmaceuticals, Aug 2013 | |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| Biogenes | Berlin, Germany | Antibodies |
| , | Business revoked Jan 2022 | |
| , | Acquired by Catalent, Feb 2021 | |
| , | Dated website, uses flash | |
| , | Acquired by Caire, Jun 2020; fka Spirometrix | |
| , | Bought by Gilead, May 2015, $65M | |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| , | Website taken over Sep 2023 - Dec 2023 | |
| , | Exceptionally dated website Nov 2019 | |
| MedAbome | Fremont, CA | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| , | Now Agenus | |
| , | ||
| , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job | |
| , | Acquired by Senexa Life Science, May 2022 | |
| , | Website taken over Nov 2023 - Feb 2024 | |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| , | Bought by PBL Assay Science | |
| , | Dated website, cant find any employees | |
| , | Now Signature Therapeutics | |
| Synergy Health Utrecht | Nieuwegein, Netherlands | Pharmaceutical Services |
| , | ||
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| , | Shut down Mar 2023 | |
| , | Founder gone Apr 2021 | |
| , | Renamed Decipher Biosciences, Jan 2019 | |
| Nephros | South Orange, NJ | Dialysis Devices |
| , | Acquired by Takara Bio, Mar 2017, $50M | |
| TissUse | Berlin, Germany | Multi Organ chip |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | ||
| Cellink | Blacksburg, VA | Bioprinting |
| , | No business filings Apr 2020 - Nov 2023 | |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Cradle | Amsterdam, Netherlands | AI Protein Design |
| iCad inc | Nashua, NH | Diagnostics Imaging |
| Amadix | Valladolid, Spain | Diagnostic development |
| , | Changed name to ViroMed, 199 | |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| |
Durham, NC | OmniAb provides access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. |
| , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 | |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | Acquired by Genzyme, Dec 2004, $1B in stock | |
| , | Gone 2017 | |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| Lonza | Williamsport, PA | Contract Manufacturing, Reagents, Stem Cells, Services |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| , | Renamed Zimmer Biomet | |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| , | ||
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Panaxia | Lod, Israel | Medical Cannabis |
| ReactDx | Melbourne, FL | Wireless Monitors |
| Epic Sciences | San Diego, CA | Diagnostics |
| Roche | Laval, QC | Diagnostics |
| , | ||
| Synthis | New York, NY | Immunotherapies |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Neuway Pharma | Bonn, Germany | CNS drug delivery platform |
| , | Renamed AveXis, Jan 2014 | |
| , | Website hijacked Nov 2023 - Jan 2024 | |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| , | Bought by Merck, Feb 2019, $300M | |
| , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 | |
| , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management | |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| , | Acquired by Charles River, Mar 2021; $875M | |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| , | Acquired by Bruker, Feb 2022 | |
| , | Winding down Jul 2024 | |
| , | Shut Down June 2017 | |
| , | Shell became cryptocurrency company | |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| , | Shell company | |
| , | Website gone 12-21-13, CEO switched jobs Oct 2013 | |
| Lygos | Berkeley, CA | Biologically-derived specialty chemicals |
| , | Bought by Takeda, Feb 2020, up to $330M | |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Stryker | San Jose, CA | Medical Devices |
| , | Acquired by TNK Therapeutics, Apr 2017 | |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| , | ||
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| , | Assets acquired by Rising Pharmaceuticals, Dec 2016 | |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| , | ||
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| , | Website down Dec 2023 - May 2024 | |
| , | Presumed Gone | |
| , | ||
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B | |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Guangdong Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Retrotope Pharmaceuticals | Los Altos, CA | Stabilized Lipids |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Bought by Zambon, Jul 2019, $160M + $405 Milestones | |
| Upsher-Smith | Madison, NJ | Small Molecules, Generics |
| PharmaLex | Oslo, Norway | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Bought by Medtronic, Jun 2019 | |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| , | Closed, 2015 | |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| , | Website down Dec 2019 - Aug 2020 | |
| , | Acquired by Tris Pharma, Apr 2021 | |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| CASI Pharmaceuticals | Rockville, MD | Small Molecules |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| , | Website down Jul 2020 - Dec 2020 | |
| , | ||
| , | Acquired by Boehringer Ingelheim, Dec 2020 | |
| Lupin | Somerset, NJ | Generics |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| , | Gone | |
| , | Acquired by Zoll, Jun 2019 | |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| , | ||
| Universal Cells | Seattle, WA | Non-immunogenic cells |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| , | Now rEVO Biologics 2013 | |
| , | Acquired by Pierre Fabre, Sep 2023 | |
| Promab Biotechnologies | Richmond, CA | Proteins, iPS Cells, Kits, etc. |
| , | Changed name to Arbutus Biopharma, Jul 2015 | |
| , | Website down May 2021 - Dec 2021 | |
| , | Bought by Gilead, Nov 2011, $11B | |
| GT Biopharma | Brisbane, CA | Antioxidant Therapeutics, Antibodies |
| , | Acquired by Nuclea Biotechnologies | |
| , | Now Beckman Coulter Genomics | |
| Gencove | New York, NY | Genome Sequencing |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| , | ||
| , | ||
| , | ||
| , | Acquired by SR Pharma 2005 | |
| , | Merged into Longevity Biomedical | |
| Denison Pharmaceuticals | Lincoln, RI | Contract R&D and Manufacturing Services; Topical and Oral Semisolids, Solutions, and Suspensions |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| , | Website copyright 2011 as of Mar 2019 | |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Cytiva | Freiburg, Germany | Medical Devices |
| , | Renamed Noveome Biotherapeutics, Jan 2009 | |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| , | Website copyright 2011 as of May 2019 | |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| , | Acquired by Anokion, Sep 2019 | |
| , | Acquired by Impax, Mar 2015 | |
| Inceptua | Berlin, Germany | Therapeutics, Clinical Trial Services |
| , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma | |
| , | Acquired by Becton-Dickinson, May 2020 | |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| , | Renamed Abata Therapeutics, Nov 2021 | |
| , | No website Dec 2019 - May 2023 | |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| , | Renamed Caidya, Oct 2022 | |
| , | Founders gone as of May 2021 | |
| , | Liquidating, Feb 2025 | |
| , | Website down Mar 2024 - Jul 2024 | |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| , | Acquired by Merck KgAA, Dec 2021 | |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Website gone, side gig for sole employee, annual report filed Feb 2017 | |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| , | Changed name to AmpliPhi Biosciences | |
| , | Acquired by eurofins, Jan 2016 | |
| , | Acquired by Bayer, Jun 2021 | |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| , | Acquired by BD, Mar 2011 | |
| , | Now SVA | |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Abbott Diagnostics | Santa Clara, CA | Diagnostics |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| , | Acquired by Rho, Dec 2021 | |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| , | Merged with Adicet Bio, Sep 2020 | |
| , | Acquired by Allergan, Sep 2016, $50M + milestones | |
| , | Website gone Dec 2017; Habitually late filing business docs | |
| , | Website gone May 2020, no employees on LI | |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| , | Split and became Medvacon | |
| , | Website gone Feb 2020 - Aug 2021 | |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| Anacura | Evergem, Belgium | Analytical |
| , | Website gone Sep 2017 | |
| , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 | |
| , | Sole product acquired by Eli Lilly, Oct 2015 | |
| , | Now Telephus Biosciences | |
| , | Website gone Jan 2021 | |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| Enterey | Irvine, CA | Life Science Consulting |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| , | Acquired by Stryker, Nov 2018 | |
| , | Website down Feb 2024 - Jul 2024 | |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| , | Website down May 2020 - Sep 2020 | |
| , | Acquired by Invitae, Aug 2017 | |
| , | Bankrupt, sold to investors, Feb 2024 | |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| |
Cambridge, MA | Symbiosis provides fill/finish manufacturing slots with expertise of vaccines, mAbs and more, offering integrated services to get drug products from manufacture to release. |
| 2 Bridge | Zoersel, Belgium | Consulting |
| , | Gone 2019 | |
| , | Merged with Pioneer Surgical to become RTI Surgical | |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| , | Renamed Charmwood Discovery, Sep 2023 | |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Nura Bio | South SF, CA | Small Molecule |
| , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 | |
| MJL Bio | Seoul, Korea | IP Consulting |
| , | Closed 2016 | |
| |
Hombourg, France | Solvias is a world leading CRO/CDMO, providing integrated analytical services to pharma, biotech and medical device industries for all stages of drug development. |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| , | Acquired by Acino, Dec 2023 | |
| , | Acquired by Medtronic, May 2022, $1.1B | |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| , | Website down May 2021 - Sep 2021 | |
| , | Gone | |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | ||
| , | Website gone Oct 2022 - Feb 2023 | |
| , | Shut down Dec 2019 | |
| , | Bought by Medtronic, Aug 2015, $458M | |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| , | Assets acquired by Syneron, Mar 2012 | |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| , | Acquired by Cerecor, Sep 2018, $26.6M | |
| , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 | |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| , | Renamed Celine Biotechnologies | |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology | |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| , | Website down Oct 2023 - Nov 2023; Penny stock | |
| , | Acquired by Allergan 2013 | |
| Texcell | Evry, France | Contract Research |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| , | Website gone Aug 2019 - Aug 2021 | |
| Doer Biologics | Hangzhou, China | Biologics |
| , | Renamed Celsee Diagnostics, Oct 2015 | |
| , | Gone, 2012?; fka Zelos Pharmaceuticals | |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| , | Website down Nov 2023 - Dec 2023 | |
| , | Acquired by Biolex 2005 | |
| , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 | |
| , | Bought by PCLS Apr 2014 | |
| , | Shut Down May 2021 | |
| , | Website down Aug 2023 - Jan 2024 | |
| , | No real employees, no news since 2016 as of Apr 2021 | |
| , | Acquired by GE Healthcare, Apr 2017 | |
| , | Renamed Isolation Bio, Sep 2022 | |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| ACI Medical | San Marcos, CA | Arterial Assist Device |
| , | Dissolved May 2019 | |
| , | Dissolved Dec 2017 | |
| , | Merged with Oxitope to become Calluna, Jan 2024 | |
| , | Acquired by Merck KGaA, 2006 | |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| , | ||
| RS Research | Lausanne, Switzerland | Nanocarriers |
| , | Bought by Spectrum Pharmaceuticals Jul 2013 | |
| , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 | |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| , | Seems gone Jul 2015 | |
| , | Shut down, Dec 2018 | |
| , | Now Tamir Biotechnology | |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| , | Acquired by AbbVie, May 2020, $63M | |
| Innocare | Beijing, China | Cancer Treatments |
| , | Acquired by Agilent, €68M, Dec 2016 | |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| , | Now part of Adiso Therapeutics | |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 | |
| , | Renamed PTM BIO | |
| Amoytop Biotech | Xiamen, China | Biologics |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| , | Acquired by Synthélabo, 1991 | |
| , | Acquired by Celgene, Dec 2016 | |
| Issar Pharmaceuticals | West Orange, NJ | Small Molecules |
| CoaguSense | Fremont, CA | Coagulation monitor |
| , | Acquired by Medtronic, Nov 2004 | |
| , | ||
| , | Acquired by CuraCyte, fka Strohtech | |
| , | Now owned by American Heart technologies | |
| , | Gone 2018 | |
| , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k | |
| , | Gone May 2007? | |
| , | Assets bought by Matritech 2007 | |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| , | Website taken over and for sale, April-Jun 2018 | |
| Crown Aesthetics | Dallas , TX | Acne scar reducing device |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| , | Acquired and took on StemCells Inc name | |
| , | Bought by CareDx Jun 2014 | |
| , | ||
| , | Bankrupt, Apr 2017 | |
| , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 | |
| , | Renamed Rebiotix | |
| , | Disappeared, no info | |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| , | ||
| , | Acquired by JCR Pharmaceuticals, Apr 2020 | |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| , | Ceased development, may be trying to sell product | |
| , | Renamed Piedmont Animal Health | |
| , | Acquired by Dr. Reddy's Laboratories | |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Achilles Therapeutics | London, UK | Personalized Cancer T cell Therapies targeting neoantigens |
| , | ||
| , | Website down Feb 2021 - Sep 2021 | |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| , | Website Gone. Company? Probably | |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Altasciences | Harleysville, PA | Contract Research |
| , | Acquired by Bio-rad, 2021 | |
| , | Renamed Nivalis Therapeutics | |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| , | Now VBL Therapeutics | |
| , | Merged with ImmunArray, Aug 2019 | |
| Abcam | Fremont, CA | Antibodies |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| , | Acquired by Provista Life Sciences, Dec 2006 | |
| , | ||
| , | ||
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| , | Website redirecting strangely Apr 2021 | |
| , | Acquired by Fortis Life Sciences, Mar 2022 | |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| , | Website down May 2022 - Oct 2022 | |
| , | Acquired by Gilead, Sep 2022 | |
| , | People who left in 2018 still on website Jan 2021. Everyone has another job. | |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| , | Merged with Smithkline Beecham in 2000 to form GSK | |
| , | Gone | |
| , | Website down Aug 2022 - Nov 2022 | |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| , | Company has no money and no employees, Feb 2025 | |
| , | Renamed Domain Therapeutics, 2008 | |
| AGC Biologics | Milan, Italy | Contract Manufacturing - Biologics |
| , | Merged into Delmar Pharmaceutical, Aug 2020 | |
| Emulate | Boston, MA | Organs-on-chips |
| , | Acquired by Merck, Dec 2014, $375M | |
| , | Website down Nov 2022 - Mar 2023 | |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Redoxis | Lund, Sweden | Drug development CRO |
| , | Acquired by VectIvBio, Aug 2021 | |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| , | Bankrupt, Jun 2015 | |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| , | Acquired by LXO Group, 2022 | |
| , | Acquired by SK Pharmteco, Sep 2023 | |
| , | Shut down late 2024 | |
| , | Acquired by Kiadis Pharma, Dec 2006 | |
| , | Website down Jun 2020 - Oct 2020 | |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| , | Website gone Sep 2022 - Feb 2023 | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Bought by a karate business, Aug 2012, presumably for ticker | |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| , | Website down Jun 2023 - Nov 2023 | |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| , | Shut down Jan 2025 | |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| , | Bought by Roche, Aug 2015, $190M | |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Acquiring Chinook Therapeutics, Jun 2020, taking name | |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| , | Now Taxus Caridium Pharmaceuticals | |
| STARLIMS | Hollywood, FL | LIMS |
| , | Website Down Jul 2014, Presumed defunct | |
| Coloplast | Notting Hill, Australia | Wound care, surgical, bladder, bowel devices |
| SteriPack Contract Manufacturing | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| , | Acquired by Biogen, Sep 2023, $7.3B | |
| , | Acquired by Agouron, Apr 1997 | |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| , | Renamed ImPact Biotech | |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| , | Assets acquired by newly formed Cerevast Therapeutics in 2009 | |
| , | Bankrupt/Folded, Apr 2014 | |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| , | ||
| , | Acquired by Daiichi Sankyo, Feb 2011 | |
| , | Renamed Algernon Pharmaceuticals | |
| Minghui Pharmaceutical | Hangzhou, China | Therapeutics |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| , | Website abandoned, Jan 2017 | |
| , | GSK subsidiary, no longer has own website, may have been absorbed | |
| , | Website gone, Jul 2015 | |
| , | Acquired by Tiger Aesthetics, Oct 2024 | |
| , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 | |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| , | Became Empirical Spine | |
| GSK | München, Germany | Small Molecules, Vaccines, Biologics |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| , | Quit after pandemic testing no longer needed, 2021 | |
| , | No website Oct 2021 - May 2023; fka GEMoaB | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 | |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| , | Renamed HueDx, Jan 2023 | |
| Agilent | Wilmington, DE | High-Throughput Screening Equipment, Imaging instruments |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Acquired Actavis, Oct 2012, took their name | |
| , | Renamed WaveForm Diabetes, Jun 2020 | |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| , | Renamed Bovie Medical, Oct 1998 | |
| Elevation Oncology | Boston, MA | Monoclonal Antibody |
| , | All assets acquired by Nitto Denko, Apr 2012 | |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| , | Acquired by Advanz Pharma, May 2020, $76M | |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| , | ||
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker | |
| , | Chapter 11 Bankruptcy, May 2023 | |
| , | Acquired by Fresenius Kabi, May 2022, $240M + milestones | |
| Medtronic | Memphis, TN | Medical Devices |
| , | Changed name to Bausch Health, Jul 2018 | |
| CellOrigin Biotech | Hangzhou, China | iPSC-derived innate immune cell platform |
| , | Gone 2017 | |
| , | Presumed gone | |
| , | Acquired by Alliance Pharma, Jul 2022 | |
| BA Sciences | Salem, NH | Analytical Services |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| Pfizer | Psichiko, Greece | Small Molecules, Biologics, Vaccines |
| , | Shut down Mar 2023 | |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences | |
| , | ||
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Landmark Bio | Watertown, MA | Contract Cell, Gene Therapy Manufacturing |
| Lusis | Hayward, CA | Diagnostics |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| , | Acquired by PCI Pharma Services, Oct 2018 | |
| SK Pharmteco | Corbeil-Essonnes, France | Cell & Gene Therapy Services |
| , | Website Down Feb 2025 | |
| , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 | |
| , | Website gone Jan 2024 - Dec 2024 | |
| , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 | |
| OnsiteGene | San Diego, CA | 5-minute PCR |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| , | Now PrimeraDx | |
| |
Stirling, UK | Symbiosis provides fill/finish manufacturing slots with expertise of vaccines, mAbs and more, offering integrated services to get drug products from manufacture to release. |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| , | Segment of non-life science business | |
| , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 | |
| , | Bought by Boston Scientific, Jun 2002, $300M | |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| , | ||
| , | ||
| , | Acquired by Orna Therapeutics, May 2024 | |
| , | No info. SBIR 2013 | |
| , | Ridiculous website as of Nov 2019 | |
| , | Acquired by Solvay, 2006 | |
| , | ||
| , | Shut Down, Jun 2010 | |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| , | Stopped filing reports, 2017 | |
| , | Bought by Axcan Pharma, $100M | |
| , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones | |
| , | ||
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| , | Acquired by Chiesi Farmaceutici, 1999 | |
| , | Shut Down May 2024 | |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| OBI Pharma | Taipei, Taiwan | Biologics |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 | |
| , | Renamed Mariana Oncology | |
| , | Website copyright 2008 in Mar 2019 | |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| , | ||
| , | Acquired Correvio, took name years later | |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| , | Website down Jul 2020 - Dec 2020 | |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Anagenex | Lexington, MA | Directed Evolution Platform for Small Molecule Discovery |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Lucy Scientific Discovery | Victoria, BC | Psychotropic Drug Manufacturing |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| , | Website down, June-Oct 2015 | |
| , | Acquired by Rxi Pharma, Jan 2017, stock | |
| , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix | |
| , | Acquired by GE Healthcare, Aug 2011 | |
| Vicinitas Therapeutics | South SF, CA | Protein stabilization platform to develop novel therapeutics in cancer and genetic disorders |
| , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 | |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| , | Renamed Spring Science | |
| , | Website closed Sep 2022 - Nov 2022 | |
| , | Acquired by Pace Life Sciences, Aug 2022 | |
| , | Renamed Epion Therapeutics, Jul 2023 | |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Advarra | Columbia, MD | Regulatory Consulting |
| , | Acquired by NanoSurface Biomedical, Sep 2019 | |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| , | Bought by NAMSA, Aug 2021 | |
| Cyxone | Malmö, Sweden | Immunomodulating cyclotides for the treatment of autoimmune diseases |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Parexel | Harrow, UK | Clinical Research |
| , | Bankrupt - Assets sold to Veridex, Jun 2008 | |
| NIOX | Oxford, UK | Asthma management device |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| Revel Pharmaceuticals | San Francisco, CA | Therapeutic Enzymes |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| , | Bought out by investors, Mar 2013. Not sure what will happen | |
| iVexSol | Lexington, MA | Lentiviral vectors |
| , | Shut down Jan 2022 | |
| , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus | |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| ProtiFi | Fairport, NY | Sample, Protein Prep |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| , | Acquired Wellinks, Jan 2020, took name | |
| , | Sold platform to Eterna, May 2023 | |
| , | Shut down | |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| , | Acquired by MedImmune, Nov 2014 | |
| Stryker | Salt Lake City, UT | Medical Devices |
| , | Now Kirax | |
| , | Changed name to Luc Therapeutics, Oct 2015 | |
| , | Dissolved, Jun 2024 | |
| Acumed | Beijing, China | Medical Implants |
| , | Renamed Annapurna | |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| , | Acquired by Roche, Feb 2020 | |
| IRRAS | Stockholm, Sweden | Intracranial Drainage, Access, Monitoring |
| , | Renamed Akero Therapeutics, Jun 2018 | |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| , | Renamed OrphAI Therapeutics, Sep 2023 | |
| , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones | |
| , | Gone 2018 | |
| , | No updates since 2008 | |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Alercell | Bozeman, MT | Molecular Diagnostics |
| TRIFARMA | Rozzano, Italy | APIs |
| , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 | |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| , | Seem gone | |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| , | Website Gone Sep 2017; Presumed an SBIR one and done | |
| , | Renamed VIP Pharma, Feb 2019, website gone | |
| , | Acquired by Integra, Feb 2017, $240M | |
| CovalX | Woburn, MA | Protein Complex Analysis |
| , | Acquired by AngioDynamics, 2013 | |
| , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 | |
| , | Renamed Lumanity, Mar 2022 | |
| , | Liquidated Mar 2018 | |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| , | Believed defunct, Never registered as MA business, had SBIR grant | |
| BioNTech | Planegg-Martinsried, Germany | Small Molecules |
| , | Acquired by Nitto Denko Avecia, Oct 2016 | |
| , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 | |
| , | ||
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| XS Innovations | Leiden, Netherlands | Vascular Access Device |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| , | Renamed Callaion | |
| , | Renamed Channel Therapeutics, Nov 2024 | |
| , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 | |
| , | Changed name to AOBiome, May 2013 | |
| , | Acquired by Integer, Oct 2023 | |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| , | Acquired by AliveCor, Jun 2021 | |
| , | All programs halted or disposed of by 2016 | |
| Sengenics | Kuala Lumpur, Malaysia | Diagnostic services to enable the discovery & validation of autoantibody biomarker signatures |
| , | Acquired by Vaccitech, Dec 2021 | |
| Catalyst Clinical Research | Raleigh, NC | Clinical research solutions to the global biopharmaceutical industry |
| , | Centessa Company | |
| , | ||
| , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones | |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| , | All employees gone, no info, presumed gone | |
| , | Dissolved, Dec 2017 | |
| , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech | |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| , | Acquired by Mayne Pharma, Jul 2013 | |
| Charnwood Discovery | Loughborough, UK | Chemistry Services |
| , | Renamed Cadent Therapeutics, Oct 2017 | |
| OD-OS | Teltow, Germany | Retinal Laser |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| , | Acquired by GSK, Oct 2008, $57M | |
| , | Acquired by Genzyme, Oct 2006 | |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| , | Website Gone, Mar 2017 | |
| , | Acquired by Quest Diagnostics, Jul 2017 | |
| , | Acquired by Omicia, Jan 2017 | |
| , | Assets bought by Ipsen, 2008 | |
| , | Website down Oct 2021 - Feb 2022 | |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| , | Website Down May 2024 - Nov 2024 | |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| , | Website down, Aug 2015 - Gone | |
| , | Website under construction May 2020 - Mar 2021 | |
| Arthrex | Naples, FL | Arthroscopy Devices |
| , | Acquired by Exalpha Biologicals, Jun 2018 | |
| , | Doctor owner still indicates it exists, but doubtful | |
| , | ||
| Recipharm | Lainate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| , | Acquired by Merck, Mar 2024, $680M | |
| , | Formerly LabCentral, seems gone | |
| , | Acquired by Ethicon, May 2022 | |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| IntelGenx | Saint-Laurent, QC | Drug delivery platforms |
| , | Merged with LENZ Therapeutics, Mar 2024 | |
| , | Website down Apr 2021 - Sep 2021 | |
| , | Located on the Lobbying street in DC (K Street), no news 2018-2023 | |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| , | No website, spinout website gone Jan 2020 - Aug 2021 | |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| , | now part of KeyPoint Clinical Research | |
| Birdotech | Shanghai, China | CDRMO |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout | |
| , | Website now Canadian Pharmacy | |
| , | Website gone | |
| , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 | |
| , | Bankrupt 2009, closed 2013 | |
| Amide Tech | Cambridge, MA | Peptide Synthesis |
| Nanjing TransThera Biosciences | Nanjing, China | Small Molecules |
| OpenBench | San Francisco, CA | Small Molecule Screening |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 | |
| , | Website down Oct 2020 - Feb 2021 | |
| Tierra Biosciences | San Leandro, CA | Synthetic Biology |
| , | Acquired by Shockwave Medical, Apr 2023, $100M | |
| , | Website down, Dec 2017-Feb 2018 | |
| , | Renamed Resolian, May 2023 | |
| , | ||
| , | Renamed Enabled Therapeutics, Aug 2024 | |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| , | Seems to have been a shell to transfer pain asset | |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| , | Shut down Dec 2024 | |
| , | Website gone Jun 2016, CEO only employee on LI | |
| , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 | |
| , | Website Gone Jan 2019 - Dec 2019 | |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Angle plc | Guildford, UK | Liquid Biopsy |
| MilliporeSigma | Cuyahoga Heights, OH | Buffers & Media |
| , | Acquired by Foundation Medicine, Jun 2020 | |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Inotrem | Paris, France | Peptide Therapy |
| , | Changed name to TE Connectivity, Mar 2011 | |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| NETRI | Lyon, France | Organ-on-a-Chip |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| , | Acquired by CODA Biotherapeutics, Feb 2020 | |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Modifi Biosciences | New Haven, CT | Small Molecules |
| , | IP and most assets sold to Fluidigm 2010 | |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| , | ||
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M | |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| , | Acquired by Takeda, Jan 2005 | |
| , | Renamed 180 Life Sciences | |
| , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 | |
| , | Renamed DWK Life Sciences | |
| , | Closed 2014 | |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Spirit Pharmaceuticals | Ronkonkoma, NY | OTCs |
| Idience | San Francisco, CA | Cancer Therapies |
| Mendelian | London, UK | Rare Disease Diagnosis |
| LabConnect | Johnson City, TN | Lab Services |
| , | Acquired by Abbott, Dec 2014, $495M | |
| , | Shut Down late 2023 | |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| , | Shut down Sep 2024; Website down Apr 2024 - May 2024 | |
| , | Acquired by Axcan 2011, $17.5M + $195M milestones | |
| Medtronic | Louisville, CO | Medical Devices |
| , | Merged with Novalung, 2013 became Xenios | |
| , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights | |
| , | Acquired by Novartis, Feb 2024, $2.9B | |
| , | Renamed Perlara PBC, Oct 2016 | |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| , | Acquired by Medtronic, Feb 2009, $700M + milestones | |
| , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 | |
| , | Shut down Jul 2023 | |
| , | Acquired by Solid Biosciences, Dec 2022 | |
| Actylis | Port Washington, NY | Raw Materials |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| , | Renamed Seed Therapeutics | |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| , | No news 2017-2022 | |
| Menarini | Florence, Italy | Biologics |
| , | Assets sold to Greiner Bio-One, May 2018 | |
| , | Website down Jul 2020 - Jan 2021 | |
| , | Website redirecting to eurobio scientific, Nov 2019 | |
| , | Dissolved Dec 2018 | |
| , | Acquired by Sevion Therapeutics, May 2014 | |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| Roche | Welwyn, UK | Small Molecules |
| , | Acquired by Oncimmune, Mar 2019 | |
| Immatics Biotechnologies | Houston, TX | Personalized T-cell Directed Immunotherapies |
| Dirui Industrial | Changchun, China | Automated Assays |
| Getinge | Fairfield , NJ | Medical Technology |
| , | Shut down 2018 | |
| , | Shut down Aug 2019 | |
| , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 | |
| , | Website down Apr 2021 - Sep 2021 | |
| Alphazyme | Jupiter, FL | Custom Enzymes |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| , | Renamed EPIX Therapeutics, Aug 2018 | |
| Agrisera | Vännäs, Sweden | Antibodies |
| Novasecta | London, UK | Pharma Consultancy |
| Souffle Therapeutics | , | |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Steris | Mentor, OH | Contamination Control |
| , | Doesn't seem active Dec 2021, no updates since 2015 | |
| LKC Technologies | Gaithersburg, MD | Electrophysiology Systems |
| , | Gone. No info | |
| , | 10 year old company with no product or website | |
| , | Merged with Laboratoires Dausse in 1970 to become Synthélabo | |
| , | Acquired by J&J, Jul 2024, $1.25B | |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Ultragenyx Pharmaceutical | Cambridge, MA | Small Molecules, Biologics |
| Coeptis | Wexford, PA | Cell Therapies |
| , | Gone post 2022 | |
| Medtronic | Minneapolis, MN | Medical Devices |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Rad AI | San Francisco, CA | Radiology Software |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Genseq | Dublin, Ireland | Genetic, biopharma services |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| , | Acquired by Proteintech, Oct 2020 | |
| , | Website gone Apr 2019, no annual report filed 2017 or 2018 | |
| , | ||
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 | |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| , | Shut down Jan 2024 | |
| , | Bankrupt, Liquidation | |
| , | Shut down 2016 | |
| , | Website gone Jul 2022 - Oct 2022 | |
| SoundBite Medical | Montréal, QC | Wire-based devices and generator technology that delivers shockwave energy within the cardiovascular system to treat chronic total occlusions |
| , | No website Dec 2019 - May 2023 | |
| , | Website gone May 2021; fka Telephus Medical | |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| , | Acquired by Thermo Fisher, Jan 2023, $2.6B | |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 | |
| CYTOO | Grenoble, France | High Content Screening |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| Tides Medical | Lafayette, LA | Biologics |
| Gentronix | Cheshire, UK | Toxicity Testing |
| , | Renamed Binx Health | |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| , | Acquired by Shire, 2005 | |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Destiny Pharma | Brighton, UK | Antimicrobials |
| , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 | |
| , | Acquired by Agilent, Jan 2023 | |
| , | Technically exists Feb 2024, no updates since 2018 | |
| , | Website Gone Oct 2016; Est 2000 | |
| , | Renamed Scorpius Biomanufacturing, Dec 2022 | |
| SK Pharmteco | Rancho Cordova, CA | Cell & Gene Therapy Services |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Pace Analytical | Huntersville, NC | Analytical Testing |
| , | Renamed Scios, Mar 1992 | |
| Visiopharm | Hoersholm, Denmark | AI Research - Diagnostics, Pathology |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono | |
| , | Acquired by ERG Clinical, Apr 2018 | |
| Cromos Pharma | Portland, OR | Clinical Research |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| , | Subsumed into parent company, May 2024 | |
| , | ||
| , | Website down Jul 2024 - Dec 2024 | |
| , | Acquired by Lantheus, Feb 2023 | |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| , | No website Jan 2020 - Aug 2021 - seems to be no employees | |
| , | Acquired by Precision for Medicine | |
| , | Changed name to Ansun Biopharma 2014 | |
| , | Shut down, Feb 2016 | |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Grifols | Durham, NC | Biologics |
| , | Acquired by Moderna, Jan 2023, $85M | |
| , | Renamed EchoNous, Jul 2020 | |
| , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics | |
| , | Acquired by Occulo, Apr 2018 | |
| Flamingo Therapeutics | Leuven, Belgium | RNA Therapeutics |
| Opis Research | Desio, Italy | Clinical Research |
| Cidara Therapeutics | San Diego, CA | Small molecules, peptide |
| , | Renamed Luminelle | |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 | |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| SimBioSys | Champaign, IL | Tumor Analysis Software |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| , | Gone 2016 | |
| InvivoGen | San Diego, CA | Life Science Reagents |
| , | Bought by Winteam Pharmaceutical | |
| , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 | |
| , | Acquired by Acelyrin, Jan 2023 | |
| , | Merged with Urigen Pharmaceuticals, Jul 2007 | |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| , | Acquired by Altasciences, Feb 2021 | |
| , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real | |
| , | ||
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| , | Shut down June 2021; fka Reserva | |
| , | Liquidating Jan 2021 | |
| Agenus | Lexington, MA | Biologics, Contract Manufacturing |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 | |
| , | Assets purchased by Zoll Medical, May 2009, $12M | |
| , | Acquired by Novaremed, Sep 2021 | |
| , | ||
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Liquidating Apr 2025 | |
| , | ||
| RQM+ | Monroeville, PA | Regulatory compliance consulting |
| , | Renamed Karo Pharma | |
| Lupin | Mumbai, India | Generics |
| , | Website down May 2023 - Dec 2023 | |
| , | Assets acquired by Qiagen, Mar 2017 | |
| , | Acquired by Santen, Jul 2016 | |
| Sinotherapeutics | Shanghai, China | Generics |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| , | ||
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| , | Website down Dec 2021 - Apr 2022 | |
| Memmert | Eagle, WI | Lab Equipment |
| , | Merged with Bard1 Life Sciences, Jul 2020 | |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Acumed | Hillsboro, OR | Medical Implants |
| , | Bought by Concordia Healthcare Dec 2013 | |
| , | Bought by Clinical Data | |
| , | ||
| , | Website Gone, Mar 2017, site taken over by snoring info | |
| Pharmazz | Greater Noida , India | Small Molecules |
| , | Website from 2008 | |
| , | Professor-run, 10 years, nothing happened 2013-2023 | |
| MabPlex | Yantai, China | Biologics CMO, Contract research |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| , | Website Gone, Feb 2016 | |
| KCAS Bioanalytical | Olathe, KS | Bioanalytical & Biomarker Services |
| , | Life Science business acquired by Pall, Feb 2014 | |
| Vigonvita | Suzhou, China | Small Molecules, Generics |
| Mesoblast | New York , NY | Regenerative Medicine |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| , | Gone | |
| , | Part of A&Z Pharmaceutical | |
| , | Gone | |
| , | ||
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| , | Website gone, Dec 2018 | |
| , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones | |
| , | Renamed aVaxziPen | |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Pfizer | Surrey, UK | Consumer Healthcare |
| , | Acquired by Volcano, May 2014, $115M | |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Vibliome | New York, NY | Small Molecule Kinase Inhibitors |
| , | Surrendered Business License in Ca Dec 2019 | |
| , | Bankrupt Jun 2024, selling assets | |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| , | Renamed Adhex Pharma, Mar 2020 | |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| , | Acquired by ICU Medical, Oct 2015 | |
| , | Acquired by New River Pharmaceuticals, 2011 | |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| , | Merged with Peptides International to become Vivitide, Jan 2021 | |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| , | Acquired by MedImmune 2005, Up to $175M | |
| , | Website down Apr 2023 - Sep 2023 | |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| Qynapse | Paris, France | Imaging Analysis |
| , | Acquired by Virax, Mar 2014 | |
| , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics | |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones | |
| , | Merged with Serina Therapeutics, Mar 2024 | |
| , | ||
| , | Merged with Ayala Pharmaceuticals, Jan 2023 | |
| , | Acquired by AstraZeneca, Feb 2024, $1.2B | |
| , | Gone Jul 2015, some assets acquired by Agenus | |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| , | Tech acquired by Mundipharma, 2017 | |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| , | Renamed Icoria, Aug 2004 | |
| Anavasi Diagnostics | Redmond, WA | Covid Diagnostics |
| Bionoxx | Yangsan-si, Korea | Tumor-targeting Antigen |
| , | Merged with Hospira 2010 | |
| , | Acquired by Kriya Therapeutics, Sep 2023 | |
| , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo | |
| , | Shut down Sep 2021 | |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| , | Acquired by SYGNIS, Jun 2008, $6M | |
| , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 | |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Crista Biologics | , | |
| , | Gone? | |
| , | Acquired by BTG plc, Dec 2014, $475M | |
| , | Renamed Tiakis Biotech, Sep 2022 | |
| , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones | |
| , | Website gone May 2024 - Jul 2024 | |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| , | ||
| , | Became Garnet BioTherapeutics, Mar 2009 | |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| , | Shut Down Mar 2020 | |
| , | ||
| Ardelyx | Fremont, CA | Gastrointestinal Therapeutics |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| , | Bought by Abbott | |
| , | Acquired by NextPhase Medical Devices, May 2021 | |
| , | Renamed AVI BioPharma, Sep 1998 | |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| IQVIA | Parsippany, NJ | Clinical Research |
| , | Website down Dec 2023 - Jul 2024 | |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| , | Changed name to Modus Therapeutics, Oct 2016 | |
| Mainz Biomed | Mainz, Germany | Molecular Diagnostics |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| , | Acquired by Pfizer Apr 2021 | |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| , | Website gone Mar 2022 | |
| Lightpoint Medical | Amersham, UK | Surgical Imaging Technology |
| , | Bought by AstraZeneca Nov 2015, $2.7B | |
| , | Changed name to Sesen Bio, May 2018 | |
| , | Bankrupt 2009, Assets transferred to Calicimedica | |
| ActiTrexx | Mainz, Germany | Cell Therapies That Avoid Transplant Rejection |
| , | Website gone, Apr 2018 | |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Grace Therapeutics | Laval, QC | Small Molecule, Medical Food |
| , | Rebranded as Forbius | |
| , | Website down Aug 2023 - Apr 2024 | |
| , | Bought by Novartis, Nov 2016, $665M | |
| , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 | |
| , | Merged with TorreyPines Therapeutics, Jun 2006 | |
| , | Merged with OncoC4, Sep 2024 | |
| Amarin | Bridgewater, NJ | Small Molecules |
| , | Renamed Phoresa | |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| , | Renamed Dice Therapeutics | |
| , | Renamed Verix Health | |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| , | Bought by DePuy Synthes, May 2016 | |
| , | Website down May 2019 - Nov 2019 | |
| |
Shanghai, China | WuXi Biologics is a biologics & vaccines CRDMO for antibodies, ADCs, recombinant proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| , | ||
| , | Bought by Celgene, Jul 2015, $7.2B | |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| , | Bought by Perrigo, Jul 2011, $540M | |
| , | Website down Dec 2023; Not registered in MA, Aug 2022 | |
| , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 | |
| , | Renamed Quantum BioPharma, Aug 2024 | |
| , | ||
| , | No website, Apr 2018-Dec 2019 | |
| , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M | |
| , | Website down Dec 2019 - Oct 2020 | |
| Alliance Spine | San Antonio, TX | Spinal implants |
| , | Renamed Dexcel Pharma USA, Oct 2024 | |
| , | ||
| , | Gone 2018 | |
| , | Acquired by Recursion, May 2023, $40M | |
| , | Merged with Synteract, became SynteractHCR | |
| , | Renamed Cardiospire, Oct 2022 | |
| Ipsen | Sumter, SC | Biologics |
| , | Acquired by Amgen, $3.7B, Oct 2022 | |
| , | Renamed Zeteo Biomedical, 2023? | |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| , | Website down Feb 2023 - Sep 2023 | |
| , | Part of LFB, Formerly GTC Biotherapeutics | |
| bioMerieux | Hazelwood, MO | Diagnostics |
| , | ||
| , | Bought by Celldex 2009, $94.5M | |
| , | Bought by Astellas, Aug 2018, up to $109M | |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| , | ||
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Acquired by Bio-Techne, Sep 2017 | |
| , | Shut down 2020 | |
| Scorpion Therapeutics | Boston, MA | Small Molecules |
| , | ||
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| , | Acquired by BioMarin, Nov 2014, $680M+milestones | |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| , | Gone, site redirecting to Nigerian pharmacy | |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| Nuvation Bio | New York, NY | Oncology Treatments |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| , | Changed name to Altimmune Sep 2015 | |
| , | Closed Mar 2013, technology may have segued into scPharmaceuticals | |
| Parion Sciences | Durham, NC | Mucosal Targets |
| , | No website Jul 2021 - May 2023 | |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| , | Now Radient Pharmaceuticals | |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| , | Bought by TFS International 2013 | |
| Serif Biomedicines | , | Gene Therapy |
| , | Acquired by LifeSpan Biosciences, Jul 2019 | |
| , | Gone | |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| , | Acquired by Orgenesis, Oct 2020 | |
| , | Liquidated early 2022 | |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| , | Seems to have gone out of business, 2021 | |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| , | Shutting down Feb 2021 | |
| , | Acquired by Orgenesis, Apr 2020 | |
| , | No website Mar 2020 - Aug 2021; Only Google hit is a patent | |
| , | Acquired by Synthetic Biologics, Mar 2022 | |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| , | Merged into Manhattan Pharmaceuticals, Mar 2010 | |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| , | ||
| GenKOre | Seoul, Korea | Gene-editing therapies |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| , | Website moved to a marketing agency domain | |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| , | Bought by Luminex 2011 | |
| , | Website gone May 2021 | |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Lupin | Coral Springs, FL | Generics |
| , | Acquired by Vernalis | |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| , | Services suspended, May 2017 | |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| , | Bought by Teva, Jun 2013, $40M + $125 milestones | |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| , | Bought by Techne, Jun 2013 $104M | |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| , | Changed name to NuGenerex Diagnostics, Sep 2018 | |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Natco Pharma | Telangana, India | Generics, APIs, Contract Manufacturing |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| NanoGroup | Warszawa, Poland | Medical Nanotechnology |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Lundbeck, Mar 2018, $123M | |
| , | Acquired by Bio-Rad, Oct 2011, $162M | |
| , | Renamed Synaptogenix, Dec 2020 | |
| , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 | |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 | |
| Pharmexon | Prague, Czech Republic | Consulting |
| , | ||
| , | Ludicrously old website, Nov 2019 | |
| , | Acquired by Takeda | |
| , | ||
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| , | Inactive Mar 2024; fka LaCell | |
| , | Acquired by Hyperion, Jun 2014 | |
| , | Acquired by Integer, Dec 2021 | |
| , | Gone Oct 2020 | |
| Baxter | Jayuya, PR | Medication Delivery |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| , | Renamed Allucent, May 2022 | |
| , | Bought by Shire Mar 2013 | |
| , | Renamed Therini Bio, Feb 2020 | |
| , | Acquired by Novartis, Jan 2020, $9.7B | |
| Almac | Craigavon, UK | Pharmaceutical Services |
| NextPharma | London, UK | Contract Research & Development |
| |
Killorglin, Ireland | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | Renamed Klotho Neurosciences, Sep 2024 | |
| , | Bought by Roche, Aug 2014, 8.5B | |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| Laboratoire Aguettant | Lyon, France | Injectables |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| nference | Cambridge, MA | Clinical AI |
| , | Bought by Organon, Jan 2005 | |
| , | ||
| , | Renamed Caraway Therapeutics, Oct 2019 | |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| , | Website down Jun 2021 - Jan 2022 | |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| , | Renamed Herophilus, Jan 2021 | |
| , | Website down Mar 2023 - Dec 2023 | |
| , | Shut down 2014 | |
| , | Shut down Dec 2024 | |
| , | ||
| , | Renamed Curia, Jul 2021 | |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| , | Merged with Hana Pharm, 1996 | |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones | |
| , | Acquired by Pfizer, Dec 2023, $43B | |
| , | Website gone Nov 2019 - Oct 2020 | |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| , | Acquired by Equillium, Feb 2022, $329M | |
| , | Renamed ConcertAI | |
| , | Acquired by Illumina, May 2018 | |
| Caregen | Anyang, Korea | Peptide R & D |
| Recipharm | Strängnäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Bought by Amgen $420M Jun 2007 | |
| , | Renamed NeurMedix, 2016 | |
| , | Renamed AirLife | |
| Angle plc | Plymouth Meeting, PA | Liquid Biopsy |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| GT Molecular | Fort Collins, CO | PCR Kits |
| , | Renamed Allied Medical, Dec 2023 | |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| , | Shut down Feb 2008 | |
| Synerlab Group | Entzheim, France | Contract Manufacturing |
| , | Renamed TheraPix Biosciences Nov 2013 | |
| , | Acquired by J&J, Jan 2003, $88M | |
| Lumen Bioscience | Seattle, WA | Biologics |
| , | Q2 Solutions subsidiary now part of IQVIA; fka Pacific Biomarkers | |
| Teleflex Medical | Beaconsfield, UK | Surgical and Medical Devices |
| , | Bought by Daiichi Sankyo, Nov 2014 | |
| , | Acquired by Sanofi, May 2024, $1.7B | |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| , | Renamed Auris Health, Mar 2018 | |
| , | Renamed Aneuvo, Dec 2021 | |
| , | Acquired and merged with Aurinia, Sep 2013 | |
| , | Liquidated Sep 2024 | |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| Tranquis Therapeutics | Redwood City, CA | Immunotherapeutics |
| , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 | |
| , | Shut down May 2020 | |
| , | Founded 2017, No info, President gone Mar 2019 | |
| , | Regenerative Medicine - gone post 2009 | |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| , | Acquired by Opko Health, Feb 2011 | |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Bespak | Morrisville, NC | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| , | Renamed Nexien BioPharma, Oct 2018 | |
| Novartis | San Diego, CA | Small Molecules, Vaccines, Biologics |
| , | Website down Feb 2022 - Jul 2022 | |
| , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M | |
| , | Renamed Drumroll Health | |
| Alkermes | Wilmington, OH | Small Molecules |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Elixir Medical | Milpitas, CA | Stents |
| , | No news 2019 - Aug 2024; employees list other jobs on profiles | |
| , | Acquired by J&J, 2023 | |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| Cue Biopharma | Boston, MA | Immunotherapy |
| Antibiotice | Valea Lupului, Romania | Generics |
| Biotia | Brooklyn, NY | AI Genomics |
| , | Assets acquired by Merit Medical, Mar 2009 | |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| , | Assets Sold to Eisai 2011 | |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Xertecs | Müllheim, Germany | Pharmaceutical Manufacturing Equipment |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| , | Gone, Mar 2015 | |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| , | Website down Apr 2023 - Sep 2023 | |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| , | Employees gone, Website down Oct 2024 | |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus | |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| , | Business inactive in CA, likely didn’t make it out of incubator | |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| , | Renamed RAPT Therapeutics, May 2019 | |
| , | 11 year old side-gig with no website as of Nov 2019 | |
| Eikon Therapeutics | Hayward, CA | Single Particle Tracking |
| , | Acquired by Bruker, Oct 2018 (80% stake) | |
| , | Filed Chapter 11 Bankruptcy, Feb 2019 | |
| , | Acquired by Medix Biochemica, Nov 2023 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Assets auctioned | |
| , | Website down Mar 2022 - Apr 2022 | |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| HiFiBiO Therapeutics | Paris, France | Single cell technologies for drug discovery |
| , | Website Gone, Company Fate Unknown | |
| Auxilart | Tokyo, Japan | Digital Drug Production Simulations |
| Anoixis | Natick, MA | Pharmacometric Services |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 | |
| , | Acquired by Catalent, Aug 2018 | |
| , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 | |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Molecular Assemblies | San Diego, CA | Enzymatic DNA synthesis technology |
| , | ||
| , | Now Vermillion | |
| , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 | |
| Xertecs | Piscataway, NJ | Pharmaceutical Manufacturing Equipment |
| , | Renamed Pepper Bio, Oct 2021 | |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| , | Website gone Mar 2024; LI page gone Nov 2023 | |
| Cambridge, MA | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 | |
| , | Bought by Orchid Pharma, Aug 2006, $3M | |
| , | Renamed Athira Pharma, Apr 2019 | |
| , | Assets sold, shell sold to Cyclacel, Dec 2005 | |
| Sapere Bio | Durham, NC | Sample collection, biomarker analysis |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Octapharma | Vienna, Austria | Plasma Products |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| , | Renamed conoGenetix Biosciences | |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| , | Website gone Dec 2023 - Feb 2024 | |
| , | Renamed Avalo Therapeutics, Aug 2021 | |
| Dermavant Sciences | Morrisville, NC | Small Molecules for Dermatology Indications |
| , | Acquired by Caprion Biosciences, Apr 2019 | |
| , | ||
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Celerion | Montreal, QC | Clinical Research |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| , | ||
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| , | Merged into ARIAD, Sep 2008 | |
| BioBridges | Morrisville, NC | Consulting |
| , | Website down Oct 2018 - Dec 2020 | |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| CeQur | Luzern, Switzerland | Insulin pump |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| , | ||
| , | preeclampsia POC test | |
| , | Website down Aug 2024; No business Filings 2023-2024 | |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| , | Acquired by Merck, Aug 2015, $605M | |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| , | Merged with Xdynia to become Cavion, Aug 2014 | |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| , | Renamed Xell, 2014 | |
| , | Assets acquired by Synovis Life Technologies, Jul 2009 | |
| , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 | |
| , | Acquired by Janssen Pharmaceutical, Aug 2014 | |
| , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna | |
| , | Merged into Anesiva, Aug 2009 | |
| , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout | |
| , | Shut down late 2020 | |
| , | Bought by Bayer Apr 2013 | |
| , | Gone | |
| , | ||
| , | Changed name to Aravive Biologics, Nov 2016 | |
| , | Acquired by Allergan, Nov 2016, $125M | |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Diagonal Therapeutics | Cambridge, MA | Agonist Antibodies |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| , | No news since 2015 as of Dec 2019. Website gone Nov 2016 | |
| , | Acquired by Concept Life Sciences, Aug 2015 | |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 | |
| , | ||
| , | Founder extradicted for stealing trade secrets | |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| , | Acquired by Natus, Jan 2023 | |
| , | ||
| Median Technologies | Shanghai, China | Imaging Phenomics |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| , | Renamed Labyrinth BioPharma | |
| , | Bankrupt 2010 | |
| , | Acquired by Trice Medical, Feb 2019 | |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Gregor Diagnostics | Madison, WI | Prostate Cancer Diagnosis |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| , | Acquired by J&J, Nov 2017 | |
| Fluke Biomedical | Cleveland, OH | Wide range of medical devices |
| , | Website gone, company presumed gone 2020 | |
| , | Seems to be a research library now | |
| , | Acquired by and converted to Cardiorentis | |
| , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones | |
| , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 | |
| , | Renamed Biorez, 2016 | |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| , | Acquired by Exact Sciences, Oct 2020 | |
| , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 | |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Armonica Technologies | Carlsbad, CA | Long-read sequencing platform |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 | |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Getinge | Växjö, Sweden | Medical Technology |
| , | Acquired by Kinetic Concepts, Nov 2012 | |
| , | Merged into BioCardia, Aug 2016 | |
| , | Liquidating, May 2020 | |
| , | ||
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| , | business filings late Apr 2023, website copyright 2014 in Feb 2025 | |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Orchestra BioMed | New Hope, PA | Medical devices |
| , | Website down Apr 2022 - Aug 2022 | |
| Sharp | Allentown, PA | Contract clinical trial services and commercial packaging services |
| , | President left in 2018, not registered in MA | |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| , | Shell pivoted to blockchain | |
| , | Website down Dec 2023 - May 2024 | |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Psivant | Boston, MA | Physics-driven Drug Design |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| Trace Biosciences | Portland, OR | Imaging Agents for Neurosurgery |
| , | Gone? | |
| , | Merged with Epirus, Jul 2014 | |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Renamed Nafas Medical, Mar 2016 | |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics | |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Dimension Inx | Chicago, IL | 3D printed grafts, ceramics |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| , | Acquired for Ticker, Sep 2024 | |
| |
Cambridge, MA | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| , | Now TrovaGene | |
| , | Website gone Jul 2015 | |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Renamed Xylo, Jan 2025 | |
| , | ||
| , | Acquired by Absorption Systems, Dec 2017 | |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 | |
| , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones | |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| , | Marked as closed on Google, Nov 2019 | |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| , | Website gone, President has new job | |
| Integer | Plano, TX | Medical & Surgical Devices |
| , | Acquired by Evotec, Jul 2022, €23M | |
| , | ||
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| , | Shut down Dec 2017 | |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| , | Liquidating, Apr 2024 | |
| TriWest Research Associates | San Diego, CA | Clinical Trials |
| JS Innopharm | Shanghai, China | Small molecule oncology medicines |
| , | No website, seems gone as of May 2019 | |
| , | Bought by Transcept | |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| , | Renamed NexEos Bio | |
| , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info | |
| , | ||
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| , | Inactive, Jun 2017 | |
| , | Different company operating at location, dated website, no employees on LinkedIn | |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| , | Bought by Abbott 2010 | |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| , | Acquired by LGC, Jul 2017 | |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research | |
| , | Acquired by Inotiv, Apr 2021, $22M | |
| , | Website down Nov 2022 - Mar 2023; not registered in MA | |
| , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones | |
| , | Website down Apr 2022 - Aug 2022 | |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| , | Acquired by ReNeuron, Aug 2007, $4M | |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| DP Clinical | Rockville, MD | Clinical Research |
| , | Website lapsed, Sep 2017 | |
| , | Inactive as of Mar 2018 | |
| , | Website down Sep 2024; business filings late May 2024 | |
| , | Shut down Aug 2024 | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Shut down Jun 2020 | |
| Oragenics | Tampa, FL | Oral Care Probiotics |
| , | Website down Aug 2023 - Apr 2024; fka AgaMatrix | |
| ResearchDx | Irvine, CA | Diagnostics |
| , | ||
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| , | Renamed Atec Spine | |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M | |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| , | Website Gone Nov 2018 | |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Pharmaron | Xi`an, China | R&D Services |
| , | Acquired by KBI Biopharma, Jan 2018 | |
| , | Acquired by MilliporeSigma, Oct 2019 | |
| Compugen | San Francisco, CA | Biologics |
| , | Lead program acquired by GSK, Oct 2024. No info prior to then | |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| , | Website gone Nov 2022 | |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Stago | Maastricht, Netherlands | Diagnostics |
| Accellacare | Raleigh, NC | Clinical Research |
| , | ||
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| , | Acquired by Siemens Healthineers, Oct 2019 | |
| , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 | |
| , | Acquired by Zymenex, Nov 2009 | |
| , | Seem gone | |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Mott | Farmington, CT | HPLC system components, Filtration |
| , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive | |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| , | Renamed Concerto HealthAI | |
| , | Shut down so owner could spend more time skiing | |
| , | Bought by Allergan, Nov 2016, $600M + milestones | |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| , | Company appears active in court, doubtful they are scientifically active | |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| , | Rebranded as Siamab Therapeutics, Jul 2014 | |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| , | Website gone Aug 2017 | |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| , | Bankrupt, 2013 | |
| , | ||
| , | Website Gone, Oct 2014 | |
| , | Website copyright 2014, no location, no employees | |
| Sun Valley Research Center | Imperial, | Clinical Research |
| Sonavex | Baltimore, MD | Ultrasound |
| , | Merged with VBI Vaccines, took their name Oct 2015 | |
| , | Renamed Release Therapeutics | |
| Degron Therapeutics | Shanghai, China | Molecular glue-based targeted protein degradation drug discovery platform |
| , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR | |
| , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio | |
| RenovoRx | Los Altos, CA | Catheters |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| , | Website down Apr 2021 - Sep 2021 | |
| Sangon Biotech | Shanghai, China | Antibodies & Lab products |
| , | Acquired by LabCorp Dec 2011 | |
| , | Acquired by Infinity Life Sciences, Jun 2022 | |
| , | Integrated into Aixial Group, May 2023 | |
| , | ||
| Ambu | Ballerup, Denmark | Medical Devices |
| , | Acquired by Pacific BioLabs | |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| , | No news since 2011 as of Dec 2020, presumed gone | |
| , | Founders and other employee gone, Dec 2021 | |
| , | Bought by J&J, Jun 2013, $1B | |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| , | 2007 website as of Mar 2019 | |
| , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 | |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Xybion | Frankfurt, Germany | Cloud LIMS, Quality |
| |
Cranbury, NJ | WuXi Biologics is a biologics & vaccines CRDMO for antibodies, ADCs, recombinant proteins, mRNA & pDNA from mammalian & microbial expression systems. |
| , | Acquired by Inscripta, Sep 2018 | |
| , | Website down Dec 2021 - Apr 2022 | |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| , | Acquired by Solvay Jun 1999 | |
| , | Renamed Epsilogen, Apr 2020 | |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| , | Changed name to Taconic Biosciences | |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| , | Website down Apr 2023 - Oct 2023 | |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| ACS DOBFAR | Agrate Brianza, Italy | Contract Generics & APIs |
| Solarea Bio | Waltham, MA | Microbiome Treatments |
| , | Acquired by Lentigen, Jul 2017 | |
| , | Website down Nov 2022 - Apr 2023 | |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| , | Acquired by Sartorius, Jun 2016, $90M | |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| , | Last news 2013, website © 2015, not in WI business registry | |
| , | Merged with Disc Medicine, Jan 2022 | |
| , | Merged with BridgeBio, Jan 2021 | |
| Asuragen | Austin, TX | Diagnostics |
| , | renamed PlateletBio | |
| , | Liquidated | |
| , | Acquired by Genentech, Nov 2018 | |
| , | Website down Apr 2024 - Sep 2024 | |
| , | Acquired by Zoll, Dec 2014 | |
| Altasciences | Montréal, QC | Contract Research |
| , | Gone before Jun 2015 | |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Vaxxas | Cambridge, MA | Vaccine patch delivery system |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| , | Acquired by Roche, May 2020 | |
| , | Acquired by Biotage, Jan 2019 | |
| , | Website gone Aug 2022 - Dec 2022 | |
| argenx | Boston, MA | Antibody therapies |
| AMAL Therapeutics | Geneva, Switzerland | Therapeutic Vaccines |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| , | Merged with FingerPrint Diagnostics to become Pronostics | |
| , | ||
| Tirupati | Pune, India | Generics |
| , | Website redirecting to Takeda; Site Gone Sep 2013 | |
| , | Acquired by Jazz Pharmaceuticals, May 2021 | |
| , | Bought by Acorda Therapeutics, Jan 2016, $363M | |
| , | Website down Dec 2024 - Feb 2025, the taken over by scammers | |
| , | Acquired by AlloVir, Nov 2024 | |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| , | Acquired by Bio-techne, Jun 2018 | |
| , | Gone late 2019 | |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| , | Merged into KalVista Pharmaceuticals, Jun 2016 | |
| , | Acquired by ProPharma Group, Jan 2019 | |
| , | Website taken over May 2024 - Sep 2024 | |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| , | Acquired by Novasep, Jul 2009 | |
| , | Merged into Avant Diagnostics, Mar 2016 | |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Geron | Foster City, CA | Small Molecule |
| Astellas | Meppel, Netherlands | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| , | Website down Oct 2021 - Feb 2022 | |
| Lavipharm | Peania Attica, Greece | Small molecules |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| Revagenix | San Francisco, CA | Antibiotics |
| , | ||
| , | Merged with Finch Therapeutics, Oct 2017 | |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| , | Acquired by Myriad Genetics, Aug 2018 | |
| , | Renamed AFG Solutions, Nov 2004 | |
| , | Merged with Astra to form AstraZeneca 1998 | |
| , | Website taken over | |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| , | Closed down, Feb 2018 | |
| , | Renamed Centricity Vision, Jun 2020 | |
| , | ||
| , | No website no info. 1996 SBIR grant. Seems to be an umbrella group | |
| , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating | |
| , | Bought by Allergan, Sep 2016, $639M | |
| , | Renamed Rein Therapeutics, Jan 2025 | |
| , | Renamed Altrubio | |
| , | Acquired by Medtronic, Aug 2020 | |
| , | Now Smithers Pharma Services | |
| , | Gone | |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| Intera Oncology | Wellesley, MA | Oncology and Neuromodulation Drug Delivery |
| Emergent Biosolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| , | Acquired by Alkermes, Feb 1999 | |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| , | ||
| , | Acquired by Fresenius Kabi, Feb 2019, $2B | |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Eilean Therapeutics | Dover, DE | Small Molecule for Hematologic Malignancies |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| Armonica Technologies | Albuquerque, NM | Long-read sequencing platform |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| DyNAbind | Dresden, Germany | Drug discovery technology available for partnership |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| THERAtRAME | Liege, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Bexson Biomedical | Santa Barbara, CA | Subcutaneous Drug Delivery |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Vigil Neuroscience | Watertown, MA | Microglia-based Therapeutics for Neurodegenerative Diseases |
| , | Acquired by reverse merger with Solexa, 2005 | |
| , | Defunct? | |
| , | Shut down Feb 2008 | |
| , | Acquired by West Pharma, May 2016 | |
| , | Website gone | |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| , | Website down Jul 2022 - Oct 2022 | |
| , | ||
| , | Gone | |
| ProAxsis | Belfast, UK | Detection and measurement of active protease biomarkers |
| , | Website taken over Jun 2020 | |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| , | Shut down Apr 2021 | |
| , | Changed name to Humanigen, Jul7 2017 | |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| , | Assets moved into Revolution Medicines, Sep 2018 | |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 | |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| , | Shut down Feb 2015 | |
| , | Shut Down Feb 2019 | |
| , | Bought by Celgene, Jan 2017, $300M + $475 milestones | |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| , | Website gone Sep 2017, no employees | |
| , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell | |
| , | Website down Dec 2020 - May 2021 | |
| Orion | Espoo, Finland | Drugs, Diagnostics, Veterinary medicine, etc. |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Aspen Neuroscience | San Diego, CA | Personalized Regenerative Medicine |
| , | Acquired by Pfizer, Jun 2022, up to $525M | |
| , | Renamed Ontera, Dec 2018 | |
| , | Renamed Alta Biomaterials | |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| , | Renamed Esperante Development, May 2023 | |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| , | ||
| , | Renamed Percheron Therapeutics, Nov 2023 | |
| , | Gone | |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| , | Gone, CEO charged by SEC with being con artist | |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| , | Shut down Jul 2021 | |
| Accellacare | Bristol, TN | Clinical Research |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| , | Renamed ReWalk Robotics, Oct 2014 | |
| , | Acquired by Precision for Medicine, Sep 2017 | |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| , | Website gone Jul 2020 - Mar 2021 | |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Acino, 2006 | |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| Proteome Sciences | Surrey, UK | Proteomics |
| Ansh Labs | Webster, TX | Diagnostics Products |
| , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public | |
| Axiom Real-Time Metrics | Mississauga, ON | eClinical solutions and services |
| , | Website gone Jan 2020 | |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| , | Website not working Nov 2022 - Feb 2024 | |
| , | Acquired by Novartis, Jun 2022 | |
| , | No news 2021 - Feb 2025 | |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| , | Website Gone, Apr 2016 | |
| , | Renamed Biora Therapeutics, Apr 2022 | |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| , | Acquired by Apredica, Aug 2010, £2.7M | |
| , | Gone Jul 2015 | |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| ICB International | La Jolla, CA | BBB-Breaching Technology |
| , | Bought by Labcorp Jul 2012 | |
| , | Acquired by Medimmune, Dec 2001, $1.5B | |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| LinaTech | Suzhou, China | Cancer treatment device |
| , | Bought by CONMED, Mar 2003 | |
| , | Merged into Vernalis 2003 | |
| , | Renamed Invera Medical, Feb 2022 | |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| , | Website taken over Aug 2020 | |
| , | Shut down Jun 2021 | |
| , | Acquired by Jazz Pharmaceuticals, Sep 2011 | |
| , | ||
| , | ||
| , | Website gone Jun 2021 | |
| Lupin | Baltimore, MD | Generics |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| , | Website gone Sep 2022 - Feb 2023 | |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| , | Acquired by Patheon, Mar 2015 | |
| , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones | |
| CPC Scientific | San Jose, CA | Peptides. Custom / Catalog. |
| , | ||
| , | Acquired by Merck, Oct 2020, $2.75B | |
| , | Website down Jan 2022 - Jul 2022 | |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Founded in 2003. No info | |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 | |
| , | Closed Aug 2016 | |
| , | Bought by Arrowhead Research, Apr 2012, $23.5M stock | |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| , | Renamed QT Imaging | |
| , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 | |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| , | Presumed Gone, 2016 | |
| , | Renamed Adanate, Jul 2018 | |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| , | Acquired by Catabasis Pharmaceuticals, Jan 2021 | |
| , | Renamed Spinal Elements | |
| , | Acquired by Mentice | |
| , | Acquired by Pfizer 2006 | |
| , | Acquired by Cell Microsystems, Aug 2023 | |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech | |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| , | Changed name to Realm Therapeutics, Dec 2016 | |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| , | Renamed BioEclipse Therapeutics, Jun 2017 | |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| , | Website down Feb 2023 - Jul 2023 | |
| Targinta | Lund, Sweden | Antibodies for Cancer |
| , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 | |
| , | Gone late 2014 estimated | |
| , | Merged with Biota Holdings 2012 | |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals | |
| , | Renamed Aimmune Therapeutics, May 2015 | |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Ponce Therapeutics | Surfside, FL | Topical Ointment |
| , | Employees all gone, including founder | |
| , | Website gone Jul 2015 | |
| , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna | |
| M3 Wake Research | Los Alamitos, CA | Clinical Research |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| , | ||
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| , | Part of Sun Pharmaceuticals | |
| , | Renamed Praxgen Pharmaceuticals | |
| , | Now Trius Therapeutics | |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| , | Renamed Sarepta Therapeutics, Jul 2012 | |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Resilience | Durham, NC | Biomanufacturing |
| , | Renamed Ten63 Therapeutics, 2020 | |
| , | No news 2020- Oct 2024 | |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| Inscripta | Pleasanton, CA | Gene Editing Technology |
| , | Changed name to Ardelyx | |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| bioMerieux | Durham, NC | Diagnostics |
| CD Genomics | Shirley, NY | Genomics Services |
| ONK Therapeutics | Galway, Ireland | Off-the-shelf Natural Killer Cell Therapies |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| , | Folded in to R&D Systems | |
| , | ||
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones | |
| , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules | |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 | |
| ClinFlows | Hüllhorst, Germany | Clinical Data Platform |
| Indivior | Slough, UK | Addiction Treatments |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| , | Acquired by Agilent, Apr 2018, $105M | |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Alltrna | Cambridge, MA | tRNA therapies |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Acquired by Collagen Matrix, Oct 2022 | |
| , | Acquired by Novotech, Jan 2023 | |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Adjutor Healthcare | Point Cook, Australia | Medicine, Device & Clinical, Regulatory, Development and Commercialization - Australia, NZ & Globally |
| , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics | |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | Merged with Menlo Therapeutics, Mar 2020 | |
| , | Acquired by Gates & Soros and turned into nonprofit | |
| , | Bought by Novartis, $200M + milestones, Jul 2015 | |
| , | ||
| , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker | |
| , | Acquired by starpharma, Oct 2006 | |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones | |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| , | Website down Dec 2021 - Jul 2022 | |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| , | part of SK pharmteco | |
| , | Gone 2017 | |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| , | Renamed BRIJ Medical, Feb 2024 | |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| , | Shut down, Jan 2018 | |
| , | Shut down, Feb 2009 | |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| , | Website gone Oct 2021, not registered business in MA | |
| Accellacare | Wilmington, NC | Clinical Research |
| Charles River Laboratories | Memphis, TN | End-to-end contract development and manufacturing services from preclinical to commercial |
| , | Merged with Nycomed, Feb 2008 | |
| , | Business lapsed, 2015 | |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Renamed Apex Molecular, Nov 2018 | |
| , | Renamed Alpenglow Biosciences, Feb 2022 | |
| Replay | San Diego, CA | HSV Vector Gene Therapies |
| , | Renamed Atrandi, Mar 2023 | |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| , | Renamed ViaNautis Bio | |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| , | Gone 2014 | |
| , | Website down Sep 2021 - Jan 2022 | |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| , | Renamed PulseSight Biosciences, Feb 2024 | |
| , | Acquired by Supernus, Nov 2021 | |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| , | Acquired by Biodexa, May 2023 | |
| , | Merged with Syros, Sep 2022 | |
| , | 2015 startup, no website Jan 2019 - Aug 2020 | |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| , | Now Meda Pharmaceuticals | |
| , | No website Aug 2018 - Aug 2021 | |
| , | Bought by NeoStem, renamed NeoStem Oncology May 2014 | |
| Current Surgical | Washington, DC | Micro-invasive Treatments |
| Acelyrin | Agoura Hills, CA | Antibody Mimetic |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| , | Acquired by Curia, Jul 2021 | |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Vantiva Precision BioDevices | Camarillo, CA | Microfluidics Manufacturing |
| , | Website down Sep 2020 - Feb 2023 | |
| , | Changed name to Aquestive Therapeutics, Nov 2017 | |
| , | Renamed Marius Pharmaceuticals, Dec 2016 | |
| Neuraxpharm | Langenfeld, Germany | Generics |
| InnoGI Technologies | Delft, Netherlands | GI Tract Platform |
| , | Website down Nov 2022 - Mar 2023 | |
| , | Assets acquired by Phadia, Jan 2009 | |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| Anjarium Biosciences | Schlieren, Switzerland | Non-viral Gene Therapy |
| , | Website not working Sep 2023 - Aug 2024 | |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| FibroGen | San Francisco, CA | Biologics, Small Molecules |
| , | Renamed Boston Therapeutics, Nov 2010 | |
| , | Website problem Feb 2021 - Nov 2021 | |
| , | Acquired by GE, Jun 2006, $390M | |
| , | Acquired by Abbott Jan 2009 | |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| , | Bought by Bio-Rad | |
| , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems | |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Eton Bioscience | Union, NJ | Research Reagents, Sequencing, Kits, Peptides, Services, etc. |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| , | Bankrupt | |
| , | Business filings late Feb 2023; No news 2020 - Dec 2024 | |
| , | Renamed Promontory Therapeutics, May 2022 | |
| , | Merged with Aspire Therapeutics to become Acerta Pharma | |
| iSchemaView | Menlo Park, CA | CT & MRI blood flow visualization |
| ABEC | Bethlehem, PA | Biopharmaceutical Process Equipment |
| Genfit | Loos, France | Drug Discovery |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| , | Gone 2019 | |
| , | ||
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios | |
| |
Hangzhou, China | WuXi Biologics | Biologics & vaccines CDMO for antibodies, proteins, mRNA, viral vectors & pDNA from mammalian & microbial expression systems. |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Affimed | Mannheim, Germany | Antibody Therapeutics |
| , | Bankrupt 2008 | |
| International Medical Industries, Inc. | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| , | Renamed Alkido Pharma, Mar 2020 | |
| , | Shut Down 2023; Website down Apr 2024 - Jul 2024 | |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| , | Bought by Myriad Genetics, Mar 2014 | |
| , | Seems gone. No info Dec 2015 | |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| , | Acquired by Mirum Pharmaceuticals, May 2022 | |
| , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 | |
| , | Acquired by Crescita Therapeutics, Sep 2016 | |
| , | Seems to have been folded back into AOP Orphan after previously being spun out. | |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| , | Acquired by Fujifilm, Dec 2016 | |
| Elastrin Therapeutics | Simpsonville, SC | Technology to develop therapeutics that render calcified tissue and organs supple again |
| CelliCure | Germantown, MD | Cell Immunotherapy |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| , | Renamed Alivexis, Apr 2024 | |
| , | ||
| Stem Cell Research Center | Vilnius, Lithuania | Stem Cell Research Center |
| , | ||
| , | Founded 2000, all assets acquired by BioAxone Biosciences | |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio | |
| , | Dissolved Feb 2020 | |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Seems gone, Jan 2022 | |
| , | Renamed TriSalus Life Sciences, Sep 2018 | |
| , | Renamed Kiora Pharmaceuticals, Nov 2021 | |
| , | Acquired by Altavant Sciences, Jan 2020 | |
| , | Wound down, Nov 2017 | |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Incyte | Wilmington, DE | Small Molecules |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| , | Acquired by Veracyte, Aug 2021 | |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| , | Acquired by Merck, Jan 2023, $1.35B | |
| , | Seems to be rebranded as Supeira | |
| , | Rebranded Seqens, 2019 | |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| , | Website down Oct 2022 - Mar 2023 | |
| , | Voluntarily winding down Apr 2021; fka VL34 | |
| , | ||
| , | Renamed InVivo Biosystems, Mar 2020 | |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Sharp | Macungie, PA | Contract clinical trial services and commercial packaging services |
| , | Acquired by Novo Nordisk, Dec 2021, $3.3B | |
| , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 | |
| , | Acquired by Baxter, Nov 2011, $380M | |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| DDL | Eden Prairie, MN | Device Testing |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| , | ||
| , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular | |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| , | Acquired by Merck, Nov 2019, $576M | |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 | |
| , | ||
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones | |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Website down Jun 2023 - Dec 2023; GE Ventures spinout | |
| , | Acquired by Veracyte, late 2014 | |
| , | Believe they sold their drug, then cashed out | |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| , | Website down Feb 2023 - Jul 2023 | |
| Createrna Science | Wuhan, China | Small Molecules |
| , | Shut Down Mar 2013; fka CardioVasc | |
| , | ||
| , | ||
| , | Website gone Jan 2025 - Feb 2025 | |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| , | Changed name to Vyera Pharmaceuticals | |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| , | Acquired by Covidien May 2012 | |
| , | Acquired by MacroGenics Jul 2008 | |
| , | Gone Nov 2018 | |
| Qeen Biotechnologies | Gatineau, QC | Bacteriophages |
| , | Left Incubator, Dec 2015, Gone | |
| Dornier MedTech | Sillingy, France | Urology Devices |
| DICE Therapeutics | South SF, CA | Small molecule compounds that act by unlocking protein-protein interfaces |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| , | Now Takara Bio | |
| , | No info 2019- Oct 2023 | |
| , | Asset sold to Vertex, Nov 2016 | |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| , | Acquired by scaffolding company, Dec 2008 | |
| , | Bought by Medtronic, Jan 2015, $42.9B | |
| Elutia | Silver Spring, MD | Drug-eluting biomatrix |
| , | Website down May 2021 - Sep 2021 | |
| Chimerix | Durham, NC | Small Molecules |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Brevetti CEA | Sovizzo (VI), Italy | Inspection Systems |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| , | Bought by Roche, Aug 2015 | |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| , | Acquired by GSK, Aug 2022 | |
| Johnson and Johnson | New Brunswick, NJ | Medical Devices |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| , | Merged into Argenta Discovery, Oct 2004 | |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| , | Bankrupt, 2014, product bought by group that named themselves TranS1 | |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| , | ||
| , | ||
| , | ||
| , | Renamed Koios Medical, May 2017 | |
| , | ||
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| , | Website down Sep 2021 - Feb 2022 | |
| , | Shutting down Mar 2023 | |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| , | Now Momentum Clinical Research after Merger, Mar 2024 | |
| , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M | |
| Amivas | Waterford, Ireland | Antimalarial |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| , | Bought by Dare Bioscience, Mar 2017 | |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Amicoat | Tromso, Norway | Biofilm Prevention with Antimicrobial Coatings |
| , | Acquired by Tyber Medical, Feb 2023 | |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| , | Acquired by Hologic Jun 2008 | |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 | |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 | |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| , | Shut down 2020 | |
| , | Gone Apr 2022 | |
| , | Acquired by Integra LifeSciences, Jan 2009 | |
| , | Renamed Adiso Therapeutics, Mar 2022 | |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| , | Gone | |
| , | Went out of business after recalling all its products, Nov 2004 | |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| , | ||
| , | Winding down Feb 2024 | |
| , | Website down, Mar 2018; No business filings since 2016 | |
| , | Bought by Chiesi, 2016 | |
| , | Renamed NANO MRNA, Jul 2023 | |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| , | Now Jubilant Cadista Pharmaceuticals | |
| RION | Rochester, MN | Exosome Therapeutics |
| , | Changed name to Tenax Therapeutics, Sep 2014 | |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| Mo:re | Hamburg, Germany | 3D Cell Culture Robot |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| , | Shut down 2014 | |
| , | Seems folded in to Dermago | |
| , | ||
| , | Website down Feb 2024 - Dec 2024 | |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| BiVACOR | Houston, TX | Heart replacement |
| , | ||
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| , | Acquired by Optimapharm, Nov 2020 | |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| , | Seems gone, Sep 2021 | |
| , | Renamed Editas Medicine, 2013 | |
| , | Website Gone | |
| , | Acquired by Celera, Nov 2001, $174M | |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| , | Acquired by Baxter, Dec 2021, $12.5B | |
| Akouos | Boston, MA | Gene Therapy for Hearing Disorders |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| , | No business filings since 2020 as of Jul 2022 | |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| , | Website gone May 2019 - Dec 2020 | |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| , | Website down Nov 2022 - Mar 2023 | |
| , | Website Gone | |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| CSL Behring | King of Prussia, PA | Biologics |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| , | Acquired by Astellas, Dec 2023, $175M | |
| , | Renamed Empirical Bioscience, Feb 2014 | |
| , | Shut down Apr 2024 | |
| , | ||
| , | Renamed Northway Biotech | |
| , | 2009 Press Release is only content on entire website, Dec 2019 | |
| , | Doubt they do anything | |
| , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals | |
| , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx | |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| , | Website gone Dec 2019 | |
| , | Fully integrated into Sun Pharma | |
| , | Renamed Cello Health Bioconsulting | |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| , | ||
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| , | Renamed GeneDx, Jan 2023 | |
| , | Acquired by Novartis 2010, $120M + $500M milestones | |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Nurx | San Francisco, CA | Birth Control Delivery |
| , | Assets auction, Aug 2017 | |
| , | Employees all gone Aug/Sep 2021 | |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Gone | |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| |
Garnet Valley, PA | Quotient Sciences is a drug development & manufacturing accelerator supporting clients across the entire development pathway from candidate selection to comme |
| , | Renamed Avivo, Sep 2022 | |
| , | Acquired by Natus Medical, Sep 2011 | |
| , | Website down Nov 2022 - Mar 2023 | |
| , | ||
| , | Website dated 2007 as of Mar 2018 | |
| , | Acquired by Chroma Medicine, Nov 2021 | |
| , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics | |
| , | No info from 2013 until Feb 2021 | |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| , | Company was consolidated into Irvine Pharmaceutical Services | |
| , | Acquired by VIRxSYS, Sep 2007 | |
| ViGeneron | Planegg, Germany | AAV Gene Therapy |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| ExThera Medical | Martinez, CA | Blood filtration |
| Medosome Biotec | Bloomington, IN | Small Molecules, Biologics, |
| , | Acquired by Roche, Apr 2015 | |
| , | All assets purchased by Jupiter Wellness, Jun 2022 | |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| , | Website down Feb 2020 - Jun 2020 | |
| , | Acquired by Veristat, Mar 2022 | |
| , | Bought by Asterand Bioscience, Aug 2015 | |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Exegenesis Bio | Lower Gwynedd, PA | Gene Therapy |
| , | ||
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| , | Website password protected Apr 2020 - Oct 2020 | |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| , | Renamed Wellell, Jan 2022 | |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| , | Shut Down Feb 2021 | |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| , | No site, no info, SBIR, Jul 2015 | |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Norgine | Vienna, Austria | Specialty Pharma |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| Zai Lab | Shanghai, China | Small Molecules |
| , | Out of Business | |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| , | Bought by Agilent, May 2012, $2.2B | |
| , | Now Emerald Biostructures | |
| , | No updates since 2016; moved from Seattle | |
| , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 | |
| , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 | |
| , | Acquired by cutisPharma, Jun 2019 | |
| , | Acquired by Sanofi, Jan 2020, $2.5B | |
| , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA | |
| , | Acquired by Unchained Labs, Jul 2023 | |
| , | Merged with Capricor | |
| , | Acquired by Cancer Genetics, Aug 2015 | |
| , | Acquired by Amgen, Apr 2021, $1.9B | |
| , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K | |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| , | Renamed Immune IQ? | |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Ark Biotech | Boston, MA | Intelligent Bioreactor System |
| , | Acquired by Columbia Labs, Sep 2013 | |
| , | Acquired by Ortho-McNeil, Apr 2005 | |
| , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 | |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| , | Assets acquired by Insulet, Feb 2023 | |
| , | Website redirecting to Rophibio | |
| Bionter | Basel, Switzerland | Sub-visible Particle Counting |
| , | Acquired by VBI Vaccines | |
| , | ||
| Revvity | Boston, MA | Diagnostics, Services |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 | |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| , | Website gone Nov 2015 | |
| , | Dissolving, Sep 2018 | |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Resilience | Alachua, FL | Biomanufacturing |
| , | Acquired by Onxeo, Mar 2016, €1.7M | |
| Cortechs.ai | San Diego, CA | Imaging technology |
| , | Acquired by Zymergen, Jan 2018 | |
| , | Gone | |
| , | Website down Dec 2021 - Apr 2022 | |
| , | ||
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| Attogene | Austin, TX | Rapid Diagnostics |
| , | Renamed Silony Spine, Oct 2023 | |
| NuVasive | San Diego, CA | Minimally Invasive Spinal Surgery Devices |
| , | Website gone Apr 2019 | |
| , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B | |
| Kaer Biotherapeutics | Escondido, CA | Generation and delivery of respirable aerosols |
| , | People all left or have other, real jobs | |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| , | Bought by Circassia Pharmaceuticals, May 2015, $219M | |
| Minaris Regenerative Medicine | Allendale, NJ | Cell Therapy Development Support |
| Richter-Helm BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| , | Founders gone Sep 2023 | |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| , | Bought by Heat Biologics, Mar 2017 | |
| , | Bought by J&J, Jun 2001, $11.8B stock | |
| Embecta | Parsippany, NJ | Diabetes Care |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| , | Website down Dec 2021 - Feb 2022 | |
| , | Website down May 2020 - Oct 2020 | |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Marinus Pharmaceuticals | Radnor, PA | Specialty Pharmaceuticals |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| , | Acquired by Danaher, Nov 2012 | |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| , | Website down Feb 2022 - Jul 2022 | |
| Quantigen Biosciences | Fishers, IN | Contract diagnostic tests and medical devices |
| , | Acquired by Exact Sciences, Oct 2020, $2.15B | |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | Bought by Cognate BioServices, Nov 2019 | |
| , | Website Gone May 2014 | |
| , | Founded 2013, Seems like one guy, no published progress | |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website down Apr 2019 - Aug 2019 | |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| SciQuus | La Jolla, CA | Oncology Drug Development |
| , | Seems to have rebranded as Vaxira, which is also a product | |
| , | Shut down Jul 2021 | |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals | |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Employees all gone. Website gone. | |
| , | Acquired by Bio-Rad, Apr 2020 | |
| , | Website Gone Mar 2018 | |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| , | Website Gone, Aug 2017 | |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Instil Bio | Manchester, UK | Cell Therapy |
| , | Shut down Dec 2021 | |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| , | Acquired by Cell Genesys Aug 2001, $17.4M stock | |
| , | Website Gone, Aug 2017, hired someone Feb 2018 | |
| , | Changed name to In Veritas Medical Diagnostics, Apr 2005 | |
| Ottobock | Vienna, Austria | Prosthetics |
| , | Renamed Intrexon, Aug 2005 | |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| , | Renamed Motus Therapeutics | |
| EMPECS Medical Device | Seongnam-si, Korea | Diagnostics and medical devices |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular | |
| Qualicaps | Whitsett, NC | Capsules |
| , | 2015 spinout from Fannin, no website Dec 2019 | |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| , | ||
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Catalog | Boston, MA | DNA data storage |
| , | Acquired by Masimo, Feb 2021 | |
| , | Gone | |
| Human Metabolome Technologies | Boston, MA | Metabolomics Data |
| , | Products sold to Cooper, Feb 2004 | |
| , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones | |
| , | Website gone, presumed inactive | |
| , | Renamed Clip Health, Sep 2021 | |
| Axcellerate Pharma | Piscataway, NJ | Contract Manufacturing - Small molecule, Biologics with Fill Finish and Lyophilization |
| , | Acquired by Tucker-Davis Technologies, Sep 2011 | |
| , | Bought by Thermo-Fisher, Apr 2013, $13.6B | |
| , | No updates Jan 2022 - Jan 2024 | |
| , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. | |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| , | Website down Feb 2024 - Jul 2024 | |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| , | Seems inactive, Apr 2023 | |
| , | Acquired by Sanara MedTech | |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| , | Renamed Curate Biosciences, Feb 2022 | |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| , | Part of Thermo Fisher | |
| , | Acquired by Thermo Fisher Sep 2011 | |
| , | Website down Sep 2020 - Jan 2021 | |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| , | Closed Jun 2016 after failed trial | |
| , | ||
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| , | Administration, Aug 2023; fka Rexgenero | |
| Scinomix | Earth City, MO | Lab Automation Products |
| , | Acquired by Techne, Apr 2011 | |
| , | Website gone, Dec 2015 | |
| Transcure Bioservices | Archamps, France | Preclinical Services |
| , | Merged with Ember Therapeutics, Mar 2015 | |
| , | Liquidated May 2011 | |
| , | Acquired by Berkeley Lights, Mar 2023, $57.8M | |
| , | Renamed Artivion, Jan 2022 | |
| miRNA Scientific | New York, NY | RNA Profiling Technology for Cancer Diagnosis |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Changed name to Amp Orthopedics, Nov 2011 | |
| , | part of SK pharmteco | |
| Alta Biomaterials | Carlsbad, CA | Medical Device Coatings |
| , | Gone | |
| , | Renamed Stamford Pharmaceuticals Jan 2020 | |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Delpharm | Tours , France | Contract Manufacturing |
| , | Website gone, Apr 2018 | |
| , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout | |
| Tavotek Biotherapeutics | Lower Gwynedd, PA | Biologics |
| , | Renamed Visionix Sep 2021 | |
| , | ||
| , | Acquired by IQVIA, Dec 2018 | |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated | |
| , | Website hijacked Feb 2025 | |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| , | Not sure what happened to them, ex employee declined to answer questions | |
| Laboratoires Genevrier | Antibes, France | Cell therapy for dermatology/rheumatology |
| Yumab | Braunschweig , Germany | Antibody Generation |
| , | Renamed Lucira Health | |
| , | Acquired by Astellas | |
| , | Website down Dec 2023 - May 2024 | |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
 |
Cranbury, NJ | Experic | CDMO; clinical trial supply services; formulation and process development; analytical services; dry powder inhalation; spray drying; commercial manufacturing |
| , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 | |
| , | Acquired by Merit Medical, Jul 2016, $98M | |
| , | Acquired by Medtronic, Dec 2018, $1.7B | |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| ZimVie | Westminster, CO | Dental Implants; Allografts |
| , | Website Gone, Jul 2015 | |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| BrainZell | Stockholm, Sweden | Human Brain Cell Models |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| , | Website copyright 2003 | |
| , | Acquired by Viant Medical, Sep 2019 | |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| R2M Pharma | South SF, CA | Drug Development Services |
| , | Acquired by Roche, $250M, renamed Bonum Therapeutics | |
| , | Website gone, strange urls, not sure what's going on | |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| , | Shut down Dec 2022 | |
| , | Acquired by BD, Jan 2014 | |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Syngene International | Bangalore, India | Contract Research |
| Mustang Bio | Worcester, MA | Immunotherapies |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| , | No news 2015 - Oct 2024 | |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| , | ||
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| , | Gone, website is online pharmacy now | |
| , | ||
| , | Part of Lake Chemicals & Minerals | |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| , | Shut Down 2009; fka Predix Pharmaceuticals | |
| Resilience | Hamilton, OH | Biomanufacturing |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| , | Acquired by Evgen, Mar 2024 | |
| , | Gone, 1999 | |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| , | Website down Sep 2020 - Mar 2021; BioTime subsidiary | |
| , | Liquidated, Apr 2016 | |
| , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience | |
| Sight Diagnostics | Tel Aviv, Israel | Blood Test Technology |
| , | Website taken over Dec 2024 - Feb 2025 | |
| , | ||
| , | Renamed Perseon Medical, Feb 2015 | |
| , | ||
| , | Website down Feb 2023 - Jun 2023 | |
| , | Acquired by Hikma, Apr 2022, $375M + $50M milestones | |
| , | Changed to Scidera Genomics | |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| , | CEO gone for a year, company website still lists him. Not a registered CA business | |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| , | Shut down Jul 2024 | |
| , | Renamed Enrich Biosystems, Nov 2022 | |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| , | Dissolved, Feb 2023 | |
| , | Acquired by Santen, Sep 2020 | |
| , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science | |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| , | Acquired by Sanofi, Oct 2020, $357M | |
| , | Website down Aug 2023 - Feb 2024 | |
| , | Winding Down May 2022 | |
| , | Website down Dec 2021 - Jul 2022 | |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| , | Bought by Perkin-Elmer, Mar 2015 | |
| , | Bought by Accelovance, Feb 2015 | |
| , | Shut down | |
| , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 | |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| , | Renamed Transferra | |
| , | Acquired by Pasithea Therapeutics, Oct 2022 | |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| , | Acquired by Hologic, Jun 2021, $795M | |
| Forecyte Bio | Frederick, MD | Cell , Gene Therapy CDMO |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| , | Gone late 2020 | |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| , | Acquired by ARCA Biopharma, Jan 2009 | |
| , | Founder, sole employee retired Nov 2017 | |
| , | Acquired by Human Longevity, Dec 2015 | |
| , | Website down Dec 2022 - Apr 2023 | |
| Lombard Medical | Didcot, UK | Medical Devices |
| , | Website down Jun 2024 - Nov 2024 | |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| PROGEN | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Purdue Pharma | Wilson, NC | Small Molecules |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| , | Website expired May 2020 - Mar 2021 | |
| , | Gone | |
| , | Academic, solo employee outfit | |
| , | Website down Dec 2022 - Apr 2023 | |
| , | Merged into Daiichi Sankyo, closing down Feb 2017 | |
| Longboard Pharmaceuticals | La Jolla, CA | Novel central nervous system-targeted assets |
| , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 | |
| Ventyx Biosciences | San Diego, CA | Therapeutics targeting innate and adaptive immune systems |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| , | Changed name to Lifecode | |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| , | Bought by Par Pharmaceutical, Sep 2007 | |
| , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 | |
| , | Website down Nov 2018; Website looks like it's from 2002 | |
| , | Renamed Regenity Biosciences, Mar 2023 | |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| , | Website gone Sep 2020 | |
| Sera Prognostics | Salt Lake City, UT | Personalized Diagnostics |
| , | ||
| , | Gone 2015? | |
| , | Bought by Katena Products, Jul 2017 | |
| , | No business filings 2016-2020 | |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| , | Acquired by Mesoblast, May 2010 | |
| , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 | |
| , | Acquired by Kcas Bio, Feb 2022 | |
| |
Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| , | Renamed Alcyone Therapeutics, Jan 2021 | |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| , | Dissolved Dec 2019 | |
| Aenova | Münster, Germany | Aenova’s CDMO services cover your supply chain from development to commercial production of most dosage forms for pharmaceutical, dietary supplements and animal health products |
| , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company | |
| Nabla Bio | Cambridge, MA | Antibody Design |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| , | Acquired by Euthymics | |
| , | Being Acquired by Invitae, Nov 2019, $50M | |
| , | Acquired by Akorn, Apr 2014 | |
| , | Specialized Clinical Trial Consulting | |
| |
East Chicago, IN | Grace | Custom engineered superparamagnetic silicas, chromatography resins and excipients tailored to customer specifications. Improve purity, efficiency, reproducibility and accuracy through raw materials and processing aids designed for small scale discovery through bulk production. Streamline discovery, save time, reduce guesswork. |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| , | Website gone, Aug 2017 | |
| , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI | |
| , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 | |
| , | Changed name to Respiri, Dec 2015 | |
| , | Acquired by Fitzgerald Industries, 2004 | |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| , | Aka Clinmet, Website gone Sep 2017 | |
| RDP Pharma | Romanshorn, Switzerland | Drug Delivery Technology |
| Flexomics | Waltham, MA | Screening platform for single-cell genomics |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Acquired by Quotient Clinical, 2017 | |
| , | Website down, LI gone Oct 2024; Penn spinout | |
| , | Now known as Cangene | |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| , | Acquired by Agomab, Oct 2021 | |
| , | 3D-printed orthopedic implants | |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| , | ||
| , | Renamed Brightseed, Mar 2018 | |
| , | Renamed BeOne Medicines, Nov 2024 | |
| , | Acquired by BioEnergy | |
| , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 | |
| , | ||
| , | No website activity 2014 - Dec 2020 | |
| , | Acquired by Edwards, Jul 2024, $300M | |
| , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? | |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Specialized Therapeutics | Singapore, Singapore | Commercializing Therapies in Asia-Pacific region |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Wavelength Pharmaceuticals | Petach Tikva, Israel | APIs |
| Intra-Cellular Therapies | New York, NY | Small molecules for neurology |
| , | Bought by Zimmer Biomet, $1B, Jun 2016 | |
| , | Acquired by Amryt Pharma, Aug 2021 | |
| , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 | |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| , | ||
| , | Acquired by eurofins, Jun 2017 | |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| , | Renamed Grace Therapeutics, Oct 2024 | |
| Transition Bio | Watertown, MA | Condensate technology, liquid-liquid phase separation |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| , | Gone | |
| , | Renamed Therabron Therapeutics, Dec 2014 | |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Appia Bio | Culver City, CA | Cell Therapy |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| , | Bought by Cephalon Mar 2011 | |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| , | Acquired by Conmed, Jun 2022, $145M | |
| , | Acquired by Eppendorf, Jan 2012 | |
| Neopeutics | South SF, CA | Drug discovery contract research |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Next Generation Clinical Research | Fitchburg, WI | Clinical Research |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| , | Bought by Ligand | |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| , | Shut down Jan 2024 | |
| , | Seems inactive, Dec 2023; no news 2018-2023 | |
| Abbott | Heerlen, Netherlands | Drug-Eluting Stents |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Biosion | Nanjing, China | Bispecific Antibody |
| , | Folded into Parkway Labs | |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer | |
| , | Acquired by Pharmalex, Nov 2022 | |
| , | New website coming soon May 2020 - May 2021 | |
| , | Liquidating 2021 | |
| Vernay | Suzhou, China | Fluid Control Solutions |
| , | Acquired by Lippomix | |
| , | ||
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| , | Changed name to Axys Pharmaceuticals | |
| Ergomed | Madrid, Spain | Clinical Research |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| Pharmaron | Ningbo, China | R&D Services |
| Parexel | Baltimore, MD | Clinical Research |
| , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones | |
| , | Renamed CEND Therapeutics, Jun 2020 | |
| Syngulon | Seraing, Belgium | Microbial fermentation |
| , | ||
| , | Website Gone late 2013, no info | |
| Infinitopes | , UK | Vaccines |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| , | Renamed Mediforum Pharmaceuticals | |
| Allakos | San Carlos, CA | Antibody therapeutics |
| , | ||
| , | Renamed Omiose | |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| , | Renamed Candel Therapeutics | |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| , | Shut down late 2020 | |
| , | Website down Jan 2023 - Jul 2023 | |
| , | Closed, Dec 2016 | |
| LFB | Paris, France | Plasma derived drug products |
| , | Website down Jan 2023 - Jul 2023 | |
| Endo Pharmaceuticals | Malvern, PA | Small Molecules |
| , | Now Allucent | |
| RT MicroDx | Boston, MA | Diagnostics |
| GQ Life Sciences | Alpharetta, GA | Gene Patent Query Software |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| , | Sole employee is professor, no news since 2017 as of Apr 2021 | |
| , | ||
| , | Acquired by Roche, Jul 2005 | |
| , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 | |
| , | Renamed Immune Therapeutics | |
| Zai Lab | Suzhou, China | Small Molecules |
| Adhezion Biomedical | Hudson, NC | Highly differentiated cyanoacrylate based surgical, wound management and infection prevention technologies |
| , | No Website, Apr 2014, presume gone | |
| , | Acquired by Merit Medical, Sep 2019, $50M | |
| BrainTale | Strasbourg, France | Neuro Biomarker Platform |
| , | Acquired by Consegna Pharma, Apr 2022 | |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| , | Filed Chapter 7 Bankrupt, Sep 2019 | |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Canton Biologics | Guangzhou, China | CDMO |
| , | Chapter 7 bankruptcy, Jul 2016 | |
| , | ||
| , | ||
| , | ||
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| , | Website down Aug 2024 - Feb 2025 | |
| , | Acquired by Novo, May 2024 | |
| , | Gone | |
| , | Presumed Gone | |
| , | Website gone Mar 2022 - Jul 2022 | |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| , | Merged with restor3d, May 2021 | |
| LifeScience PLUS | Mountain View, CA | Wound care |
| , | Acquired by Enliven Therapeutics, Oct 2022 | |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| , | Acquired by Qiagen, 2013 | |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| , | Website down Mar 2022 - May 2022, employees in other jobs | |
| seqWell | Beverly, MA | Sequencing Service |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M | |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| , | Shut down Dec 2019 | |
| , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics | |
| , | Renamed Aceragen Jan 2023 after having earlier acquired it | |
| , | ||
| , | Acquired by Transgenomic, May 2001 | |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| ProPharma Group | Windsor, ON | Consulting |
| , | Acquired by Boston Scientific, Aug 2022 | |
| , | Website hijacked Jun 2023 - Aug 2023 | |
| , | Basically gone | |
| , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones | |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Acquired by Efor, 2021 | |
| , | Acquired by Takara, Jan 2017 | |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| , | Acquired by Charles River, Oct 2014, $52M + $2M milestones | |
| , | Shut Down 2012 | |
| Ensoma | Boston, MA | in vivo Gene Editing |
| , | Acquired by Gingko Bioworks, Feb 2024 | |
| , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 | |
| MEI Pharma | San Diego, CA | Small Molecules |
| Hemanext | Avon, MA | Transfusion Technologies |
| , | Website down Feb 2022 - Jul 2022 | |
| , | ||
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| , | Acquired by Olympus, Jun 2010 | |
| Delpharm | L'aigle, France | Contract Manufacturing |
| NIOX | Morrisville, NC | Asthma management device |
| , | Closed Mar 2007 | |
| , | Shut down Sep 2021 | |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty | |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| , | Acquired by Qiagen, Oct 2017 | |
| , | Website down Jan 2020 - May 2020, never registered as business in MA | |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| ERresQ | Helsinki, Finland | Repurposed, New Molecules |
| , | Closed Mar 2008 | |
| Vodori | Chicago, IL | Commercial Content Software |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| , | ||
| , | Website down Dec 2021 - Jul 2022 | |
| , | Acquired by Novartis, Oct 2015 | |
| , | Acquired by Charles River Labs, Mar 2021 | |
| , | Shut down, 2012 | |
| , | Acquired by Navitas Life Sciences | |
| , | Merged with Inovio | |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys | |
| , | ||
| , | Shutting down Nov 2022 | |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Ergomed | Frankfurt, Germany | Clinical Research |
| , | Renamed Essen Bioscience, Apr 2010 | |
| , | Website taken over, Apr 2020 | |
| , | ||
| Biomia | Copenhagen, Denmark | Nature-inspired Small Molecules |
| , | Bought by Biotime | |
| , | Gone | |
| , | Acquired by ContraVir, Jun 2016, $17M + stock | |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 | |
| , | Products acquired by Cipher Pharmaceuticals, Feb 2015 | |
| , | Website down Feb 2023 - Jul 2023 | |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| KNC Laboratories | Izumo, Japan | Manufacturing Service |
| Resilience | Marlborough, MA | Biomanufacturing |
| , | Website Gone | |
| , | ||
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Rab Diagnostics | Oslo, Norway | ADC Patient Selection Diagnostic |
| Trilations | Tokyo, Japan | Strategic Consulting |
| , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 | |
| , | Merged with Synexus, Apr 2017 | |
| , | Shut Down 2019 | |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| Capsigen | Vancouver, WA | AAV Vectors |
| Endomag | Cambridge, UK | Biopsy Tracer |
| , | Renamed Vero Biotech, 2018 | |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| , | Renamed Spur Therapeutics, Jun 2024 | |
| , | Gone 2021 | |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| , | Bought by Bausch & Lomb - 2012 | |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| , | ||
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| Huons | Seongnam, Korea | Small Molecules |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| , | Shutting down Jan 2024 | |
| , | No employees on LI, Dec 2023, not registered in MN Dec 2023 | |
| , | Gone 2019 | |
| , | No website Feb 2023 - Jan 2025 | |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| , | Acquired by eurofins, Jul 2022 | |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| , | Website down Jul 2024 - Dec 2024 | |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 | |
| , | Shut down Jun 2019 | |
| , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M | |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| , | Gone. Site disappeared 2014 | |
| , | Website down Apr 2024 - Aug 2024 | |
| Zephyr AI | Tysons Corner, VA | AI Data Analysis |
| Curis | Lexington, MA | Small Molecules |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| 3PBIOVIAN | Noáin, Spain | CDMO - viral vectors, plasmids, proteins |
| Formycon | Martinsried, Germany | Biosimilars |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| , | Acquired by Corgentech in reverse merger, Dec 2005 | |
| , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 | |
| Lumenis | Beijing, China | Energy-based medical treatments |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| , | Renamed Inspyr, Aug 2016 | |
| GlycoMimetics | Rockville, MD | Small Molecules |
| , | No news Jun 2020 - Feb 2025 | |
| , | Acquired by PledPharma, Oct 2020 | |
| Abogen | Suzhou, China | mRNA |
| , | Became investment company | |
| , | Bought by Luminex 2012 | |
| , | Renamed Autobahn Therapeutics | |
| , | ||
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| MiRus | Marietta, GA | Spine Implants |
| , | Website down Dec 2023 - May 2024 | |
| , | Merged into CoImmune, Apr 2020 | |
| , | Renamed QuintilesIMS, Oct 2016 | |
| , | Acquired by Cubist Aug 2000, $31M stock | |
| , | Now Bayer | |
| D2M Biotherapeutics | Suzhou, China | Antibody Therapy |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| , | Closed 2011 | |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| , | Website down Aug 2020 - Feb 2021 | |
| , | Gone 2013 | |
| Bayer | Mexico City, Mexico | Small Molecules |
| , | Assets acquired by Ethismos Research, Nov 2017 | |
| Turn Biotechnologies | Mountain View, CA | mRNA Therapies |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| , | Changed name to Myos Corp May 2012 | |
| , | Acquired by Abcam, Oct 2021, $340M | |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| , | Assets acquired by Merit Medical, Jan 2019 | |
| , | Acquired by eurofins, Sep 2012 | |
| , | Renamed Agenus, Jan 2011 | |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Corcym | London, UK | Implants, Instruments |
| , | Website Down Jan 2022 - Feb 2022 | |
| , | Older Url for sale, newer url now for sale Dec 2019 | |
| , | Defunct Joint Venture, sold assets 2012 | |
| , | Bought by Merck, Jul 2007, $350M | |
| , | Assets acquired by i2 Pharmaceuticals, May 2017 | |
| , | Acquired by Vifor Pharma, Nov 2021, CHF20M | |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| , | ||
| , | Website gone Aug 2018; Was outdated before then | |
| Incendia Therapeutics | Boston, MA | Cancer Barrier Penetrating Therapies |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Lunit | Seoul, Korea | AI Image Analysis |
| , | folded into Kubota Vision | |
| , | Bought by Boston Scientific, 2005 | |
| Aluna | San Francisco, CA | Asthma Tracking Device |
| , | Renamed AimPlex Biosciences | |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| Biostrand | Diepenbeek, Belgium | Omics Analysis |
| , | Website down Oct 2021 - Jul 2022 | |
| , | Renamed New View Surgical, Aug 2016 | |
| Axplora | Raubling, Germany | API CDMO |
| Oncotherapy Solutions | Seattle, WA | Small Molecules, Drug Conjugates |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| , | Merged into Chromos Molecular Systems, Jun 2004 | |
| , | Bought by Allergan, Oct 2016, $200M | |
| , | Renamed Sicor | |
| , | Acquired by Proove Biosciences, May 2016 | |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| , | Shut down Mar 2023 | |
| , | Renamed MIRA Pharmaceuticals, Jan 2023 | |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| , | Website down Dec 2019 - Aug 2020 | |
| , | ||
| , | ||
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| , | Changed name to Soleno Therapeutics, May 2017 | |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| , | Gone 2003 | |
| , | Renamed Cornea Biosciences | |
| , | Business not registered since 2015 as of Sep 2019 | |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| , | Website down Sep 2020 - Mar 2021 | |
| , | Website down Nov 2020 - Feb 2021 | |
| , | Shut Down Jul 2024 | |
| , | Acquired by Thermo Fisher, Mar 2014 | |
| , | No website Dec 2018 - May 2023 | |
| , | ||
| , | Website now for a training company | |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| , | Website down Jul 2022 - Nov 2022; fka Ophthalix | |
| , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones | |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| , | Renamed ImmunityBio | |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| , | ||
| , | Ancient website, no employees on LI | |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Xellia Pharmaceuticals | Taizhou, China | Specialty Pharmaceuticals |
| CG Pharmaceuticals | Orinda, CA | Proprietary Drug Discovery Platform |
| , | Acquired by pion, May 2017 | |
| , | Acquired by Qiagen, Jan 2023, $150M | |
| Larkspur Biosciences | Watertown, MA | Cancer Immunotherapies |
| , | Acquired by Optimapharma Group, Dec 2021 | |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| , | Renamed Agenix | |
| , | No website, Seems gone | |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 | |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Invibio | Cleveleys, UK | Implants |
| , | Bought by LabCorp, Dec 2010 | |
| LiGalli | Leiden, Netherlands | Vaginal Drug Delivery Device |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| , | Shut down Mar 2023 | |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| , | Bought by Amgen 1994 | |
| , | Product acquired by Allergan | |
| , | Merged with ReShape Lifesciences | |
| , | Website down Apr 2023 - Sep 2023 | |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| , | Renamed Akribion Therapeutics, Jan 2025 | |
| , | Renamed AIM ImmunoTech, Aug 2019 | |
| , | Acquired by Sanofi, Jun 2018, $4.8B | |
| , | Reincarnated as Accure Therapeutics, May 2020 | |
| |
Cambridge, MA | Symbiosis provides fill/finish manufacturing slots with expertise of vaccines, mAbs and more, offering integrated services to get drug products from manufacture to release. |
| , | Renamed Xenix Medical, Apr 2021 | |
| , | Acquired by Marizyme, Sep 2020 | |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| , | Acquired by CoreRx, May 2021 | |
| , | ||
| , | Website gone, Jul 2015 | |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| , | Bought by Viracor-IBT Feb 2013 | |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| , | not a registered business in CA, Feb 2025 | |
| , | Website down Jul 2022 - Oct 2022 | |
| , | Acquired by MEDiSTRAVA, Jan 2024 | |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M | |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| , | Acquired by Volcano, Dec 2012, $36M | |
| , | Merged with Tekmira, Jan 2015 | |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| , | Bankrupt, Jun 2011 | |
| , | Acquired by Genalyte, Apr 2020 | |
| ProPharma Group | Fort Washington, PA | Consulting |
| , | Bought by Juno Therapeutics, Jan 2016, $125M | |
| , | Renamed Trukera Medical, Sep 2022 | |
| , | Ceased operations in 2010. Out of money. | |
| Cordis | Miami Lakes, FL | Medical Devices |
| , | Liquidated, Jun 2023 | |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Not sure what happened, no site, seem gone | |
| , | Acquired by Promethera Biosciences, Apr 2018 | |
| , | Renamed geneType | |
| Sage Science | Beverly, MA | DNA Fractionation |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| , | Former CEO referred to company in the past tense as of Mar 2019 | |
| , | Chapter 7 Bankrupt, Sep 2016 | |
| Immortagen | Coralville, IA | Bioinformatic Drug Discovery |
| Evonik Industries | Birmingham, AL | Biomaterials |
| , | ||
| , | Website down Jul 2022 - Dec 2022 | |
| , | Rebranded Provectus Biopharmaceuticals, Dec 2013 | |
| , | Website under construction Apr 2020 - Aug 2021 | |
| , | Website down Jun 2024 - Nov 2024 | |
| CorDx | San Diego, CA | Diagnostics |
| , | Website Gone 2-20-14, Taken over | |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| , | Renamed Pendulum Biosciences | |
| Zai Lab | Hong Kong, China | Small Molecules |
| , | No employees on LI, no web updates since 2014, no info on whether active | |
| , | Acquired by Avance Clinical, Sep 2022 | |
| , | Website Gone, Apr 2014 | |
| , | Closed Mar 2013 | |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| , | ||
| |
Beijing, China | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| , | Website taken over May 2021 - Dec 2022 | |
| , | Website down Apr 2021 - Sep 2021 | |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| , | Renamed Dexorgen, Jan 2024 | |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| , | Gone June 2017 | |
| , | Acquired by Neostem, Oct 2011 | |
| , | Gone 2014 | |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| , | Seem to be part of DNA Diagnostics Center, Nov 2019 | |
| , | Shut down Jan 2025 | |
| , | Merged into Avant Diagnostics, Mar 2016 | |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| , | No website Jan 2020 - Dec 2020 | |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| , | Website down Feb 2021 - Jul 2021 | |
| , | Acquired by BMS, Jul 2011, $325M | |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| , | Liquidating, Jan-May 2023 | |
| , | ||
| , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 | |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| SenzaGen | Lund, Sweden | Genomic Assays |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| , | Bought by Apogent, Dec 2001 | |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| , | Bought by BMS, Nov 2015, $300M | |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| , | ||
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Northway Biotech | Waltham, MA | Contract research |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| Scantox | Grambach, Austria | Neuro CRO |
| , | ||
| , | Gone | |
| Medice | Iserlohn, Germany | Small Molecules |
| , | Website gone more or less, Feb 2016 | |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| Abata Therapeutics | Watertown, MA | Treg Cell Therapies |
| , | Renamed Symeres, Nov 2020 | |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| , | Renamed Rock Creek Pharmaceuticals Jun 2014 | |
| , | Acquired by Element, now Element Life Sciences | |
| , | Merged with Celunol to become Verenium | |
| , | Acquired by BBI Solutions, Apr 2024 | |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| , | ||
| , | Now Intuity Medical | |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| , | Website copyright 2000 | |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| , | Renamed Caeregen Therapeutics, Aug 2021 | |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| , | Shut down Aug 2021 | |
| Nucleus Network | Melbourne, Australia | Clinical Research |
| , | Acquired by Auxeris Therapeutics, Jan 2004 | |
| GSK | Collegeville, PA | Small Molecules, Vaccines, Biologics |
| , | Renamed Roivant | |
| , | Renamed Iterative Health, Oct 2022 | |
| , | Tech sold Mar 2024 | |
| Evergreen Therapeutics | Hong Kong, China | AI Pharmaceutical Company |
| , | Acquired by Chromos Molecular Systems, Dec 2001 | |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| , | Product licensed to Dr. Reddy's | |
| , | Bankrupt, but may have come back as BBB Therapeutics | |
| , | ||
| , | Acquired by Pfizer, Feb 2007 | |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| Alimentiv | San Diego, CA | Clinical Services |
| , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M | |
| , | CA business filings late Nov 2022 - Aug 2024 | |
| Unity Biotechnology | San Francisco, CA | Aging therapeutics |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| , | ||
| , | Bought by Novartis | |
| Contraria Biotech | Siena, Italy | Antibody-derived Vaccines |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Siga | New York, NY | Small Molecules |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| , | Closed 2014 | |
| , | Website down Feb 2021 - Jul 2021 | |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| , | Closed Dec 2015 | |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| , | Acquired by EnteroMedics, Oct 2017 | |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| , | Website down May 2022 - Oct 2022 | |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| , | Acquired by Chiron, Apr 1995, $95M | |
| , | Gone | |
| , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones | |
| , | Renamed Symeres, Nov 2020 | |
| , | Renamed MapLight Therapeutics, Sep 2019 | |
| Otsuka | Tokushima, Japan | Small Molecules |
| , | Merged with NuProbe, Jan 2020 | |
| , | ||
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| , | Gone, Dec 2018 | |
| , | Bought by Stryker, Sep 2017 | |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| , | Website gone Nov 2023 - Apr 2024 | |
| Cnpair Biotech | Hangzhou, China | IVD Reagents |
| , | No website Dec 2020; Single-person company?, Dec 2019 | |
| Jubilant HollisterStier | Kirkland, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| , | Gone Jun 2009 | |
| , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 | |
| Revvity | Waltham, MA | Diagnostics, Services |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Scholar Rock | Cambridge, MA | Biologics |
| , | Bought by Currax, Sep 2019 | |
| , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences | |
| , | Acquired by Clarified Precision Medicine, Aug 2021 | |
| , | Amateurish website that is not working Jul 2015 | |
| , | Renamed Prometheus Biosciences, Sep 2019 | |
| Alumis | South SF, CA | Autoimmune Treatments |
| Abbott | Sylmar, CA | Device Manufacturing |
| , | Product failed in clinic, Apr 2019; Website gone Apr 2019 | |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| , | Out of business 2011 | |
| BIT Analytical Instruments | Schwalbach, Germany | Contract Manufacturing, Develepment |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| , | Gone pre Jun 2019 | |
| , | Acquired by Premier Research, May 2021 | |
| Encodia | San Diego, CA | Protein Analysis Technologies |
| Sinovac Biotech | Beijing, China | Vaccines |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| , | Renamed Harrow Health, Jan 2019 | |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| , | Acquired by Nanogen, Sep 2004 | |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform |
| , | Renamed Minaris Regenerative Medicine, Sep 2020 | |
| , | 20 yr old company with no info on website | |
| , | Renamed Abcentra, Jan 2019 | |
| GenEvolution | Porcheville, France | In-Vitro Toxicology Services |
| Trident Lifeline | Surat, India | Generics |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| , | Acquired by J&J, Dec 2022, $16.6B | |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Catalyst Clinical Research | Raleigh, NC | Clinical research solutions to the global biopharmaceutical industry |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| , | Website Down Nov 2022 - Mar 2023 | |
| , | Assets acquired by Avedro, Sep 2014 | |
| , | Gone | |
| , | Assets acquired by ImmunogenX, Mar 2016 | |
| , | Wound Down and Assets acquired by new-incarnation of Tolerion | |
| , | Most employees left, not registered in MN | |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Attovia Therapeutics | Fremont, CA | Proprietary biparatopic nanobody platform |
| , | Wound Down | |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| , | Website down Jan 2021 - May 2021 | |
| , | Acquired by St. Jude Medical, Octo 2013 | |
| , | Subsumed into parent Alvogen | |
| , | Acquired by Allergan, Apr 2016, $85M + milestones | |
| , | Changed name to BioQ Pharma, Oct 2015 | |
| Stryker | Portage, MI | Medical Devices |
| , | Website down Jul 2023 - Oct 2023; fka Metactive Medical | |
| , | Lab supplies, seems defunct | |
| , | Website down Apr 2024 - Sep 2024 | |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| , | Merged with RTI Biologics to become RTI Surgical | |
| Fuji Yakuhin | Saitama, Japan | Generics |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| Medtronic | Cincinnati, OH | Medical Devices |
| , | ||
| Resilience | East Norriton, PA | Biomanufacturing |
| DIMERx | San Francisco, CA | Amino Acid Prodrug Dimer |
| , | Merged with Cyclo Therapeutics, Sep 2023 | |
| , | Shut down late 2024 | |
| , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics | |
| , | Acquired by Oxford Gene Technology, Mar 2009 | |
| , | Closed Late 2013, Early 2014 | |
| , | Acquired by AstraZeneca, Feb 2024, $800M | |
| , | ||
| Apellis Pharmaceuticals | München, Germany | Cyclic peptide analog |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| , | Gone Sep 2023. Assets moved to Cortalix | |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| , | ||
| , | Now PRA Health Sciences | |
| , | Acquired by Ajinomoto, Mar 2013 | |
| , | Royalty Company, moved all assets into inVIos, Jan 2022 | |
| , | ||
| , | Acquired by Enovis, Jul 2022 | |
| , | Acquired by BioLineRx, Mar 2017, $6M | |
| , | Acquired by Precision for Medicine, Mar 2019 | |
| , | Website down Feb 2024 - Aug 2024 | |
| , | Renamed CaCy Therapeutics | |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| , | Closed down Spring 2013 | |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| , | Website down Sep 2023 - Mar 2024 | |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| , | Website gone, Apr 2018. Company CA FTB suspended | |
| Novotech | Shanghai, China | Clinical Research |
| , | Acquired by Mallinckrodt, Mar 2014, $1.4B | |
| Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| , | Aquired by Enteralia Bioscience, Nov 2024 | |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| , | Website gone Dec 2019 - Aug 2020 | |
| , | Acquired by BD, Dec 2021 | |
| , | Only info is on Centerwatch | |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Tiba Biotech | Cambridge, MA | RNA Vaccine Delivery Platform |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| , | Licensed all assets out after phase 3 failure fka Spaltudaq | |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| , | Acquired by Stryker, Oct 2011 | |
| Orchid Orthopedic Solutions | Shelton, CT | Contract Medical Device Work |
| Generation Bio | Cambridge, MA | Gene Therapy |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| Qynapse | Boston, MA | Imaging Analysis |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| , | Website dangerous, Mar 2024 | |
| , | Renamed Helixmith | |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| , | Changed name to Sapphire Therapeutics 2005 | |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| , | Acquired by Zealand Pharma, Oct 2019, up to $80M | |
| , | Acquired by Roche, Apr 2014 | |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| , | Shut down 2018 | |
| Indena | Milan, Italy | CDMO |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| , | Shut down Jan 2025 | |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| , | Website gone Nov 2017 | |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout | |
| , | Acquired by Medtronic, Jan 2014, $160M | |
| Transcend Vivoscope | Beijing, China | Biomedical Imaging |
| , | ||
| , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 | |
| , | ||
| , | Acquired by Synova Healthcare, Feb 2007, $16M stock | |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| , | ||
| , | Renamed Precigen | |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| , | Website down Apr 2022 - Jun 2022, employees virtually all gone | |
| , | ||
| , | Acquired by Astellas, Jan 2020, $3B | |
| , | Merged into parent company, Oncology Venture | |
| Akribion Therapeutics | Zwingenberg, Germany | CRISPR nucleases genetics-based cancer therapies and advanced genome editing tools |
| Symansis | Timaru, New Zealand | Reagents |
| , | ||
| , | Acquired by EvoGenix, Apr 2005 | |
| , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia | |
| , | Acquired by Graviton Bioscience, Dec 2022 | |
| Abintus Bio | San Diego, CA | Gene Therapy |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| Sengenics | Wilmington, DE | Diagnostic services to enable the discovery & validation of autoantibody biomarker signatures |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| , | Achieved "Exit" with unnamed biopharma company, Aug 2019 | |
| , | No news Jul 2017 - Feb 2024 | |
| Chimeric Therapeutics | Carlton , Australia | CAR-T Therapies |
| , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones | |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| , | Website down Dec 2022 - Apr 2023 | |
| , | ||
| ProPharma Group | Westlake, OH | Consulting |
| , | Now Abeona Therapeutics | |
| Personalis | Fremont, CA | Genome Services |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| , | Merged with Grail, May 2017 | |
| , | Changed Name to Harbor Biosciences, Feb 2010 | |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Noul | Yongin-si, Korea | Decentralized Diagnostic Platform |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| , | Renamed Gritstone Bio, May 2021 | |
| BioFluidica | San Diego, CA | Liquid Biopsy |
| , | No longer seems active, Sep 2017 | |
| , | Renamed Alcresta Therapeutics, Jun 2016 | |
| , | Acquired by Novavax, Jun 2020 | |
| , | Website down Oct 2022 - Apr 2023 | |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| 2SD Toxicology Services | Raleigh, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| , | Ran out of money, closed down 2012 | |
| , | Website down Feb 2023 - Jul 2023 | |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| , | ||
| Laboratorios Legrand | Bogotá, Colombia | Small Molecules |
| , | Acquired by Amzell, Mar 2021 | |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| , | Merged with Altimmune, Jan 2017 | |
| Biopharma Group | Diemoz, France | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| , | Acquired by Investors, Website Gone, CEO gone Aug 2016 | |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Epygen Biotech | Arvada, CO | Biosimilars |
| , | Acquired by Cerecor, Nov 2017 | |
| , | Website down Aug 2024 - Feb 2025 | |
| ADC Therapeutics | San Mateo, CA | Antibody-drug conjugates |
| , | Closed 2017 | |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| , | No website Mar 2020 | |
| , | Renamed CleanroomsUSA, Jan 2024 | |
| , | Acquired by Sanofi, Sep 2021 | |
| , | No info. 2012 SBIR grant | |
| , | ||
| , | Merged with MiniMed and Allecure to become MannKind, 2001 | |
| , | Acquired by DuPont, Apr 2015 | |
| , | Bought by bioMerieux, May 2011 | |
| , | Renamed Allora Diagnostics, Oct 2022 | |
| , | Acquired by Resilience, Apr 2021 | |
| Abbott | Longford, Ireland | Diagnostics |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Stock worthless, website gone Oct 2016 | |
| Zumutor Biologics | Bangalore, India | Biologics |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| , | Merged with Synageva | |
| , | Merged with Ayala Pharmaceuticals, Oct 2023 | |
| , | Acquired by Bard, May 2010, $200M | |
| Vivex Biologics | Atlanta, GA | Tissues |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| , | Website down Dec 2022 - Apr 2023 | |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| , | Assets acquired by Agilent, Aug 2016 | |
| , | Insolvent, technology acquired by Lindis Biotech | |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| , | Acquired by Immunicum, Dec 2020 | |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| , | Shut Down, late 2013 | |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| , | Website gone Oct 2019 | |
| Xellia Pharmaceuticals | Budapest, Hungary | Specialty Pharmaceuticals |
| , | Acquired by Apax Partners, Sep 2007, now part of Endo | |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Dornier MedTech | Webling, Germany | Urology Devices |
| , | Website down Jun 2020 - Aug 2020 | |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Apprentice.io | Jersey City, NJ | Cloud Software |
| , | Gone mid 2016 | |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| , | Bought by Sigma-Aldrich, Jan 2012, $350M | |
| , | Business Surrendered in CA, Aug 2016 | |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| , | Gone Jun 2019 | |
| , | Acquired by Gilead, Apr 2020, $4.9B | |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| , | Not sure if active, doesn’t look serious from website, Oct 2018 | |
| , | Acquired by Eisai, Dec 2009 | |
| Syngene | Cambridge, UK | Gel Imaging |
| , | Acquired by The Medicines Company, Aug 2008 | |
| , | Acquired by Dr. Reddy's, 2013, $36M | |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| , | Renamed Novita Healthcare | |
| Circadiance | Export, PA | CPAP Mask |
| , | May have spun operations into Enzyvant Sciences, Jul 2016 | |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Vortex Biosciences | Sutton, UK | Circulating Tumor Cell Identification |
| , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone | |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| , | Acquired by GenScript, Dec 2017 | |
| , | Renamed Abterra Biosciences, Aug 2021 | |
| , | Not registered as business in MA, Nov 2021, CEO has different 'real' job | |
| , | Acquired by Allergan, Dec 2017 | |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Getinge | Ankara, Turkey | Medical Technology |
| , | No website Dec 2018 - Dec 2019 | |
| , | Renamed Dendrix | |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Apotex | Toronto, ON | Small Molecule Generics |
| , | Changed name to BioVie, Apr 2016 | |
| , | Changed name to CAMP4 Therapeutics, Mar 2018 | |
| , | ||
| , | Shut Down | |
| , | Renamed Key Therapeutics, Sep 2024 | |
| Nostos Genomics | Berlin, Germany | AI Genetics |
| , | Acquired by EAG, Jul 2015 | |
| , | Merged into Ensysce Biosciences, Dec 2015 | |
| Sampled | Motherwell, UK | Biostorage |
| , | ||
| , | Acquired by Celegene, Jan 2003, $45M | |
| , | Renamed CorFlow Therapeutics, May 2017 | |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Resilience | Waltham, MA | Biomanufacturing |
| , | Acquired by Pace Life Sciences, Sep 2022 | |
| , | Website gone Feb 2014 | |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| , | Gone 2016 | |
| , | Acquired by Restech, Apr 2018 | |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Seems gone, Aug 2023 | |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| Exolitus | Kaunas, Lithuania | Exosome Production & Research |
| Claret Bioscience | Santa Cruz, CA | NGS Library Prep |
| , | Founders and employees all gone, Nov 2024 | |
| , | Shut down Apr 2005 | |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| , | ||
| TC Biopharm | Holytown, UK | Cell-based Immunotherapy |
| Helsinn | Dublin, Ireland | Small Molecules |
| Wellmarkerbio | Seoul, Korea | Biomarker-based cancer drugs |
| , | Bought by Allergan, Sep 2018, $195M | |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| , | Website down May 2023 - Dec 2023 | |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Sun Pharmaceuticals | Ankleshwar, India | Generic Small Molecules, APIs |
| , | Acquired by Eisai, Jan 2008, $3.9B | |
| , | Merged with Effimune May 2016, became OSE Immuno-therapeutics | |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| , | ||
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| , | Seems gone, owner has about 3 other jobs and five board positions | |
| , | Acquired by Angiotech, Sep 2005 | |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| , | Website down Feb 2024 - Jul 2024 | |
| Enhanc3D Genomics | Cambridge, UK | Whole Genome 3D Structure Mapping |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| , | ||
| Sanofi | Haverhill, UK | Small Molecules |
| , | Website Gone, Sep 2017 | |
| Avadel Pharmaceuticals | Chesterfield, MO | 505(b)(2) product |
| , | ||
| , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones | |
| Procella Therapeutics | Tullinge, Sweden | Cell Therapy |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Augustine Therapeutics | Leuven, Belgium | Therapeutics for Neuromuscular Diseases |
| , | Website Gone | |
| , | SF-based, Looks gone | |
| Cytiva | Amersham, UK | Medical Devices |
| Ankon Technologies | Wuhan, China | Medical Devices |
| , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience | |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| , | Bought by Sandoz, Jun 2010 | |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| MabPlex | San Diego, CA | Biologics CMO, Contract research |
| Juncell Therapeutics | Shanghai, China | Tumor-infiltrating lymphocytes |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| ANT Neuro | Hengelo, Netherlands | Neurodiagnostics & Neuroscience research |
| , | Acquired by Intrexon, $60M, Feb 2015 | |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 | |
| , | Acquired by Polyphor, Oct 2021 | |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| , | Now Kantar Health 2009 | |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Anodyne Nanotech | Boston, MA | Nanotech for Drug Delivery |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| , | Acquired by Thermo-Fisher 2008 | |
| , | Acquired by Sumitomo, Jul 2023; fka Sepracor | |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Imophoron | Bristol, UK | ADDomer based vaccines |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics | |
| , | Sold tech, shut down Dec 2024; fka Cam Med | |
| VitaCyte | Indianapolis, IN | Collagenase |
| , | ||
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| , | ||
| , | Acquired by bioMérieux, Jul 2011, $60M | |
| , | ||
| Alfasigma | Bologna, Italy | Small Molecules? |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Sanofi | North York, ON | Biologics, Vaccines |
| , | Shut down late 2023 | |
| Mikart | Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| , | Insolvent but ex-employees are running it as consultants | |
| , | Bought by Covidien, May 2009, $440M | |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| , | All assets licensed to Innovate Biopharmaceuticals | |
| , | Probably gone, not sure what happened | |
| , | Bought by Endo | |
| , | Bought by Savara Pharmaceuticals, Jun 2016 | |
| , | Acquired by Heraeus Medical, Sep 2019 | |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| , | ||
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| , | Gone | |
| , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences | |
| , | Gone | |
| Couragen Biopharmaceutics | , | |
| , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics | |
| , | Website down Jan 2023 - Jul 2023 | |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Abpro | Woburn, MA | Antibodies |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| , | Effectively defunct after scandal | |
| , | Very old, amateurish site, likely not active | |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| , | Website Gone, no news since 2007 as of Dec 2019 | |
| , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 | |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| , | Now part of Accelacare | |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| , | Gone Apr 2019; Not sure active, Dec 2016 | |
| SEQENS | Ecully, France | APIs, Ingredients |
| , | Liquidated 2011 | |
| , | Acquired by Exscientia, Nov 2018 | |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| , | Gone | |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| , | Acquired by Forest Labs, Jan 2014, $2.9B | |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| PolyQuant | Bad Abbach, Germany | Proteomics Services, Products |
| , | Merged with Ikaria Feb 2007 | |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 | |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Bayer | Bitterfeld, Germany | Small Molecules |
| , | Merged with Insmed Dec 2010 | |
| |
Newark, DE | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Bactiguard | Tullinge, Sweden | Infection Reducing Devices |
| , | Bought by GSK | |
| , | Website down Aug-Oct 2018; Active in CA database Oct 2018 | |
| , | Acquired by Charles River, Oct 2016, $64M | |
| Elegen | San Carlos, CA | DNA writing |
| , | ||
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | ||
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| , | Website gone Jun 2020 | |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| , | Renamed Inscripta, Nov 2017 | |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Inozyme Pharma | Boston, MA | Enzyme Replacement Therapy |
| Yunovia | Hwaseong, Korea | Small Molecules |
| , | Renamed MicroDose Therapeutx? | |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| , | Website under construction, Aug 2021 -May 2022 | |
| , | Renamed Velvet Therapeutics, Apr 2024 | |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| , | Acquired by Lundbeck, Oct 2019, $1.95B | |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| Getinge | Mahwah, NJ | Medical Technology |
| , | Website gone, no info Oct 2021 | |
| , | ||
| , | Website down Jul 2023 - Dec 2023 | |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| , | Website down Aug 2023 - Feb 2024 | |
| , | Website taken over, Mar 2017 | |
| , | Rebranded as Biomere, May 2016 | |
| Anatomise Biostats | London, UK | Biostatistics & Bioinformatics |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| , | Renamed Aeovian Pharmaceuticals, Sep 2019 | |
| Menarini | Dresden, Germany | Small Molecules |
| Cradle | Bay Area, CA | Cryopreservation |
| Profusa | Emeryville, CA | Real-time biosensors |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| , | Website expired Feb 2021 - May 2021 | |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | ||
| , | ||
| , | Renamed Virion Biotherapeutics, Sep 2018 | |
| , | Renamed ENDOQUEST robotics, Jun 2022 | |
| Bausch Health | Irvine, CA | Small Molecules |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Biogen | Weston, MA | Small Molecules, Biologics |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| Vericel | Cambridge, MA | Cellular Therapy |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| , | Gone 2017 | |
| Xylo | Boulder, CO | Psychedelics |
| , | Renamed Weavr Health, Apr 2021 | |
| , | No news 2017 - Oct 2024 | |
| , | Website down Mar 2024 | |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| , | Shut down Feb 2016 | |
| , | Bought by Mindray, Jul 2013, $64M | |
| , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; | |
| Omixon | Boston, MA | Next-gen sequencing products |
| , | Acquired by Diamedica, Dec 2009 | |
| Copley Scientific | Nottingham, UK | Test equipment |
| , | ||
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Inspirna | Long Island City, NY | Cancer therapies designed specifically to target cancer metastasis |
| AGC Biologics | Longmont, CO | Contract Manufacturing - Biologics |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| Pharmaron | Coventry, RI | API Manufacturing |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Tenshi Kaizen | Bangalore , India | Drug Delivery |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| , | Website down Aug 2022 - Jan 2023 | |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| , | Acquired by Discovery Life Sciences, Dec 2021 | |
| , | Founder already done in 2018 after one year | |
| GEXVal | Kanagawa, Japan | Small Molecules for Rare Diseases |
| , | Renamed Aria Pharmaceuticals, May 2021 | |
| AVEO Oncology | Boston, MA | Small Molecules |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| , | Chapter 7 bankruptcy, Aug 2020 | |
| , | ||
| , | Bought by Gilead, Aug 2006 | |
| , | Renamed NanoCellect | |
| , | Website copyright 2003 as of Jan 2019 | |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| , | Acquired by Boston Scientific, Jun 2021 | |
| , | Seem to be part of Getz Healthcare now | |
| Glenmark | Monroe, NC | Generic Small Molecules |
| , | Website down Jun 2023 - Dec 2023 | |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Akamis Bio | Abingdon, UK | Oncolytic Vaccines |
| GSK | Maidenhead, UK | Small Molecules, Vaccines, Biologics |
| QuantumBio | State College, PA | Protein characterization software |
| Gossamer Bio | San Diego, CA | Small Molecules |
| , | ||
| Certus | St. Louis, MO | Imaging Clinical Trials |
| , | Renamed Antikor Biopharma | |
| , | Closed 2008 | |
| OcuDyne | , | AMD Medical Device |
| , | ||
| , | Merged with NPS | |
| Luye Pharma | Shanghai, China | Small Molecules |
| , | French startup, no website Jun 2019 - May 2023, closed according to Google | |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| , | Acquired by Life Technologies, Dec 2009 | |
| , | Took subsidiary name - Ironshore Pharmaceuticals | |
| , | Gone before 2019 | |
| , | Renamed H-Cyte, Jul 2019 | |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| , | Shut down 2017 | |
| , | Shut down 2016 | |
| , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M | |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Hovione | Loures, Portugal | Contract Manufacturing |
| , | Changed name to Cypress Bioscience, 1996 | |
| , | ||
| , | Bought by BASF, Dec 2013 | |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| , | Bought by Baxter, Jul 2014 | |
| , | Website gone, Most of management team moved to Menlo Therapeutics | |
| RK Pharma | Pearl River, NJ | Generics |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| , | Acquired by Deinove, May 2018 | |
| , | Renamed NeuroKappa Therapeutics | |
| Rapid Micro Biosystems | Freising, Germany | Microbial Analysis |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| , | Acquired by Tecan, Aug 2018, $54.4M | |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Healionics | Seattle, WA | Biomaterials for devices |
| , | Shut down Dec 2022 | |
| , | Renamed Curapath, Oct 2022 | |
| , | Merged with AAIPharma Services, Renamed Alcami | |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Kancera | Solna, Sweden | Oncology Drug Discovery |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| , | Acquired by Mylan, Sep 2010, $550M | |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 | |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Xencor | Pasadena, CA | Antibody Discovery |
| , | Shut down May 2021 | |
| , | ||
| BTS Research | San Diego, CA | Contract Research |
| Genex Pharma | Mumbai , India | Generics |
| , | Seems gone May 2023 | |
| Stago | Taverny, France | Diagnostics |
| KVK Tech | Newtown, PA | Generics |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| , | Acquired by Cenexel, Aug 2021 | |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| , | Renamed PDL Biopharma | |
| , | Renamed Cullinan Therapeutics, Apr 2024 | |
| , | Acquired by Paragon 28, Jun 2021 | |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| |
Cranbury, NJ | Experic | CDMO; clinical trial supply services; formulation and process development; analytical services; dry powder inhalation; spray drying; commercial manufacturing |
| , | Changed name to GRI | |
| , | Shut down Aug 2021 | |
| , | Changed name to Accelerate Diagnostics | |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| , | Website down Feb 2024 - Jul 2024 | |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| , | Renamed Prena | |
| , | Liquidated Feb 2021 | |
| , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 | |
| , | Renamed Erbi Biosystems, Nov 2019 | |
| , | Renamed CJ Bioscience | |
| , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock | |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| , | Acquired by ActivBiotics, Jan 2006 | |
| Resilience | Allston, MA | Biomanufacturing |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| , | Renamed PragmaBiome | |
| , | Acquired by Tecomet, Dec 2014 | |
| Iterum Therapeutics | Dublin, Ireland | Anti-infectives |
| , | Renamed Recovery Pharmaceuticals, Dec 2002 | |
| , | ||
| , | Renamed Cytera, Nov 2018 | |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| , | Acquired by Biosynth, May 2023 | |
| Cara Therapeutics | Stamford, CT | Small Molecules |
| Zimmer Biomet | Minneapolis, MN | Implants |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| , | Acquired by InnerScope Hearing Technologies, Nov 2021 | |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| , | Bought by AstraZeneca, Feb 2007 | |
| , | Now Concordia International | |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| , | Renamed Valink Therapeutics, Nov 2023 | |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| Acutis Biosciences | Monmouth Junction, NJ | Biomarker Discovery |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| , | Founder gone, no info | |
| , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 | |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| , | Acquired by WCG, Apr 2019 | |
| , | Main assets bought by Cytori, Jan 2017 | |
| , | Acquired by Genentech, Aug 2007, $919M | |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| , | Defunct | |
| Kudo Biotechnology | Shanghai, China | mRNA CDMO |
| , | Closed | |
| , | Gone | |
| , | Rolled into Johnson & Johnson MedTech, Sep 2024 | |
| , | Renamed TheracosBio | |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| , | Acquired by Castle Biosciences, Apr 2022 | |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| OneCell Diagnostics | Cupertino, CA | Cancer Diagnostics |
| Ossur | Irvine, CA | Orthopedic Devices |
| , | Renamed Sanara MedTech, May 2019 | |
| , | License antibodies to Abcam; Bought by Ventana 2007 | |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| , | ||
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| , | ||
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| , | Acquired by Roche, Jan 2017 | |
| , | Shut down Mar 2020 | |
| , | Renamed Elion Therapeutics, early 2024? | |
| , | Dissolved Jan 2014 | |
| , | Website gone Oct 2019, company founded 2007 | |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Ocelot Bio | Redwood City, CA | Peptide therapeutic to treat complications of end-stage liver disease |
| , | Acquired by Intelligent Material Solutions, 2010 | |
| , | Changed name to ProMore Pharma, Jul 2016 | |
| , | Website down May 2021 - Aug 2021 | |
| Weatherden | London, UK | Clinical Consulting |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| , | Exceptionally outdated website Nov 2019 (ca. 2005) | |
| , | Part of Enzo life sciences | |
| , | Website down Nov 2019, late business filing 2020 | |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| , | Acquired by ImmumoPrecise, Apr 2018 | |
| , | ||
| , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals | |
| , | Gone Jun 2018 | |
| , | Website gone Aug 2019 - Dec 2020, not filing business docs | |
| , | Website down Mar 2024 - Sep 2024 | |
| , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 | |
| , | Acquired Flower Orthopedics, May 2020, took name | |
| , | Website down emails bouncing Oct-Nov 2018 | |
| , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract | |
| , | No website Oct 2021 - May 2023 | |
| , | Acquired by LifeNet Health LifeSciences, Aug 2022 | |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| , | Acquired by Essity, Apr 2017 | |
| GeneType | Charlotte, NC | Genetic Testing |
| , | Renamed Norogy Therapeutics, Nov 2020 | |
| , | ||
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| , | Acquired by Cardinal Health, Aug 2014 | |
| , | Penny stock Nov 2020, no info | |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 | |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Kronos Bio | Cambridge, MA | First-in-class therapies against historically intractable targets |
| , | Renamed Curiva, Feb 2021 | |
| , | Pivoted to investments, 2014 | |
| , | Acquired by Stryker, Jan 2021 | |
| , | Acquired by Sinovac | |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| , | Acquired by BioAgilytix, Aug 2021 | |
| , | ||
| Neurogene | Houston, TX | Genetic Therapies |
| , | Website down Nov 2023 - Mar 2024 | |
| , | ||
| Nido Biosciences | Watertown, MA | Small Molecule for Neuro Indications |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| , | Acquired by Arris Pharmaceuticals Nov 1995 | |
| , | Wound down 2012 | |
| , | Acquired by BTC Network, Aug 2016 | |
| , | Renamed Helocyte | |
| XBiotech | Austin, TX | Antibody Therapy |
| , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M | |
| , | Acquired for cash assets by energy company, Mar 2009 | |
| , | Acquired by LakePharm Mar 2016 | |
| , | ||
| , | Bought by Sanofi Pasteur 2012 | |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| , | Website down Apr 2024 - Sep 2024 | |
| , | Renamed Bravida Medical, Jun 2024 | |
| , | Renamed CN Bio, Feb 2014 | |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| , | Main program rights acquired by Novo Nordisk, Apr 2018 | |
| Greenstone Biosciences | Palo Alto, CA | |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| , | Acquired by Oryzon Genomics, Mar 2009 | |
| , | Took on Regenexx product name | |
| , | Website down Feb 2021 - Sep 2021 | |
| , | Website down Mar 2020 - Dec 2020, listed on BioNJ | |
| , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) | |
| , | Website down Jan 2022 - Jul 2022 | |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| , | Renamed Avecho Biotechnology | |
| , | Acquired by Dotmatics | |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Inotrem | Vandoeuvre, France | Peptide Therapy |
| , | Folded in to Jubilant Life Sciences? Site disappeared, no info | |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| , | Merged into NextView Diagnostics, Dec 2016 | |
| , | Acquired by LabCorp, Jun 2018 | |
| , | Now part of Abzena | |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| , | Renamed XRpro Sciences, Dec 2014 | |
| , | ||
| , | Acquired by Progenics, Jan 2013 | |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| , | Acquired by MitoKor, May 2001 | |
| , | Acquired by Clovis Oncology, Nov 2013 | |
| , | No news 2020-2023; Acquired by Collidion, 2017 | |
| , | Renamed PhageNova Bio, Nov 2018 | |
| , | Renamed Espero Biopharma | |
| , | Website down Dec 2021 - Apr 2022 | |
| , | Renamed Cortechs.ai | |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| , | Renamed CytoBioscience, Dec 2016 | |
| , | 2015 spinout from Fannin, no website Dec 2019 | |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| , | Now part of Keeler | |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| , | Part of Cellectis | |
| , | Acquired by Eli Lilly, 2006, $2.2B | |
| , | Acquired by IQVIA, May 2018 | |
| , | Acquired by Solvias, Jun 2021 | |
| , | Acquired by ATS Medical, Jan 2006 | |
| , | ||
| , | Bought by Hologic, Jul 2006, $240M | |
| , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 | |
| , | Renamed Bird Rock Bio, Dec 2015 | |
| , | Renamed Aliri, May 2023 | |
| , | Acquired by IMS Health, 2010 | |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| , | Bought by BioPort, Jun 2003 | |
| BIOS Health | Cambridge, UK | Neural interface platform |
| , | Renamed Ology Bioservices, Oct 2017 | |
| , | Gone 2014 | |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| , | Website down Sep 2023 - Mar 2024 | |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| , | Acquired by UCB, Jun 2020, $125M | |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones | |
| Pace Analytical | Oakdale, MN | Analytical Testing |
| , | Sold off assets to BioNTech in bankruptcy, May 2019 | |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions | |
| , | Part of Roivant | |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| , | Website down Oct 2022 - Mar 2023 | |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| , | ||
| , | Centessa Company | |
| , | Prana Surgical, Jan 2025 | |
| Sharp | Heerenveen, Netherlands | Contract clinical trial services and commercial packaging services |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| , | Acquired by UCB, Nov 2020 | |
| , | Was part of Actelion Pharmaceuticals | |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| , | ||
| , | Merged with Oncternal Therapeutics, Jun 2016 | |
| ZSFab | Boston, MA | 3D printed surgical implants |
| Cytovale | San Francisco, CA | Sepsis Detection |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Simpson Interventions | Campbell, CA | Visual guidance for effective cardiovascular interventions |
| , | Acquired by Agilent, Aug 2018 | |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| , | Changed name to Everist Health Jan 2011 | |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| , | Bankrupt Jun 2014 | |
| , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 | |
| , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report | |
| , | Website gone | |
| , | Acquired by Lundbeck 2009 | |
| , | Acquired by Cytiva, Apr 2024 | |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| Alcon | Fort Worth, TX | Eye-Care Products |
| , | Bought by JnJ, now Janssen Therapeutics | |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| , | Website from about 1999 | |
| Formation Bio | New York, NY | AI Drug Discovery |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Vetter | Skokie, IL | Aseptic Filling |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| , | Website gone Dec 2015 | |
| , | Renamed Encysive Pharmaceuticals, May 2003 | |
| Hikma | London, UK | Medication Delivery |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| , | Marked as closed by Google | |
| Recipharm | Karnal , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Website down Jan 2020 - Dec 2020 | |
| , | Now part of Radiant Research | |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| , | Gone 2013 | |
| , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares | |
| , | ||
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| 3PBIOVIAN | Turku, Finland | CDMO - viral vectors, plasmids, proteins |
| , | Soliciting donations on website, not a nonprofit, dated website | |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| , | ||
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| , | Renamed Calyxo, Jun 2020 | |
| , | Renamed Aquaro Histology | |
| , | ||
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Resilience | San Diego, CA | Biomanufacturing |
| , | Website gone, employees gone | |
| , | Website down Jan 2021 - May 2021 | |
| , | Website Gone, Jan 2016 | |
| CLAIRIgene | Durham, NC | Viral Vector Gene Therapy |
| , | Bought by Micrologix Biotech Apr 2004 | |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Santen | Osaka, Japan | Ophthalmics |
| , | Website down Dec 2021 - Apr 2022 | |
| , | Purchased by Meridian Biosciences, Mar 2016, $66M | |
| , | No longer active business per LA business registry, Feb 2019 | |
| , | Shut down Apr 2022 | |
| KARL STORZ Endoscopy-America | Tuttingen, Germany | Endoscopy |
| , | Bought by Bimerieux Dec 2008 | |
| , | Acquired by Beckman Coulter, 2009 | |
| , | Not a registered business in CA | |
| , | Acquired by SCIEX, Jan 2021 | |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| , | Website taken over, Oct 2017 | |
| Intratech Medical | Kibbutz Shefayim, Israel | Spiral design balloon for the treatment of acute heart attacks |
| , | Shut Down Mar 2019 | |
| , | Acquired by Exact Sciences, Dec 2017 | |
| , | Website down Sep 2023 - Mar 2024 | |
| , | Acquired by Lonza, Jul 2008 | |
| , | Acquired by Genomenon, Jun 2023 | |
| Opko Health | Woburn, MA | Biologics, Vaccines, Diagnostics, etc. |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| , | ||
| ResMed | San Diego, CA | Medical Devices |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 | |
| , | Renamed Talaris Therapeutics, Apr 2019 | |
| , | Might be Zephyrus Biosciences | |
| Tecomet | Wilmington, MA | Implant Components |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| , | ||
| Synlab | Munich, Germany | Clinical Lab Services |
| Tara Innovations | Parsippany, NJ | Contract R&D, Formulation (proprietary & contract) |
| , | Website copyright 2001 in Nov 2019 | |
| , | Renamed Oxford Drug Design, May 2017 | |
| , | Website down, Sep 2016-Mar 2017 | |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| , | Website gone, Dec 2017, single employee is founder | |
| , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout | |
| , | Est 2013, No website Jan 2020 | |
| , | Website Gone, May 2018 | |
| , | Acquired by Boston Scientific, Jul 2018, $220M + milestone | |
| , | CEO & Founder gone April 2021 | |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| , | Acquired by Cenexel Clinical Research, Mar 2021 | |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| , | Acquired by Catalent, Aug 2022, $475M | |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| |
Tyrone, PA | Grace Fine Chemical | U.S. Domestic CDMO offering process scaleup and commercialization of small molecule APIs, RSMs and intermediates. Network of 2 fully integrated sites with a world class analytical team offers an industry-leading flexible supply chain through the back integration of its intermediates. |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 | |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| , | Bought by AstraZeneca, Oct 2013 | |
| , | Bought by Pfizer | |
| , | Re-branded as Ingenus Pharmaceuticals | |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| , | Acquired by Heraeus Medical Components, Aug 2017 | |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| , | Bought by Gilead, Feb 2011, $375M + $125Milestones | |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Pall | Port Washington, NY | Filtration |
| F2G | Manchester, UK | Antifungals |
| , | Website gone | |
| , | Website down Jun 2023 - Dec 2023 | |
| , | Website weird Dec 2023 - Jul 2024 | |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| , | Website down Sep 2020 - Jan 2021 | |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| InxMed | Beijing, China | Oncology Treatments |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| , | Bought by Amgen 2000 | |
| , | Renamed AlphaCognition, Feb 2020 | |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Rapa Therapeutics | Rockville, | Cell Therapy |
| Cyclacel Pharmaceuticals | Dundee, UK | Small Molecules, Biologics |
| , | Acquired by Angle plc, Oct 2017, $6M | |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines |
| , | Acquired by Turnstone Biologics, Jan 2021 | |
| , | ||
| Stada | Bad Vilbel, Germany | Generics |
| , | Merged with Novocell & BresaGen to become ViaCyte in 2004 | |
| , | Website down Dec 2023 - May 2024 | |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 | |
| , | Acquired by Cycle Pharma, Jan 2025 | |
| Cytel | Pune, India | Clinical software, statistical services |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| , | Bought by Greatbatch, Oct 2015, $1.73B | |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| , | Management page 5+ years out of date. No employees on LI | |
| CIT Sensors | Urdorf, Switzerland | Cell Culture Sensors |
| Acertara Acoustic Laboratories | Vilnius, Lithuania | Ultrasound probe testing devices |
| Nanosonics | Indianapolis, IN | Ultrasound |
| , | Bankrupt 2013 | |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| , | Bought by Orexo, €94M, Oct 2007 | |
| , | Liquidated 2010 | |
| , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx | |
| , | Acquired by Cubist Oct 2013 | |
| , | Acquired by MiCo BioMed, May 2018 | |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| , | Renamed In3Bio, Jul 2020 | |
| , | Acquired by Kite Therapeutics, Feb 2023 | |
| , | Renamed Pendrea Bio, Aug 2021 | |
| Novotech | Seoul, Korea | Clinical Research |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for | |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| , | Business forfeited according to CA SOS | |
| Nusano | Valencia, CA | Radioisotopes |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| , | Closed 2015 after poor clinical trial results | |
| Imagion Biosystems | South Melbourne, Australia | Cancer Diagnostics, Nanotech |
| , | Gone maybe 2013 | |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics | |
| , | Part of United Therapeutics | |
| , | Website down Jan 2024 - Aug 2024 | |
| , | ||
| , | Bought by Roche, Mar 2007, $454M | |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| , | Rebranded as Ancora Heart Inc Oct 2016. | |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| , | Renamed Rize Oncology, Jan 2025 | |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| , | ||
| Biovian | Turku, Finland | Contract Development & Manufacturing |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| , | Acquired by Kashiv Pharma, Jan 2019 | |
| , | Bought by Savara for its public shell, Jan 2017 | |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| , | Merged with Grifols | |
| BioArctic | Stockholm, Sweden | CNS treatments |
| Pharmaron | Beijing, China | R&D Services |
| Apellis Pharmaceuticals | Victoria, Australia | Cyclic peptide analog |
| , | Acquired by Novo Nordisk, Aug 2023, €15M | |
| Invectys | Paris, France | DNA Vaccine |
| , | Seems to have sold itself off by Oct 2021 | |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 | |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| , | ||
| , | Website taken over | |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| NuMedii | San Mateo, CA | Data platform |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| , | Website down Dec 2020 - May 2021; Business revoked in NC | |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| , | Wound Down 2009; Assets acquired by Althea, May 2010 | |
| , | Acquired by Biosynth, Jul 2023 | |
| , | Website down Apr 2022 - Aug 2022 | |
| , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin | |
| , | Acquired by WCG, Jul 2021; fka Neurocog Trials | |
| , | Acquired by Biodesix, Jul 2018 | |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 | |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Vistin Pharma | Oslo, Norway | Generics |
| , | Gone 2015 | |
| , | Website down Jul 2021 - Nov 2021 | |
| Apollo Scientific | Manchester, UK | Research Products |
| , | Not active | |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| , | Website down Feb 2024 - Jul 2024 | |
| , | Renamed Nomic Bio | |
| , | Old company, no website, presumed defunct | |
| , | ||
| Zalgen Labs | Frederick, MD | Immunotherapy for Lassa Fever |
| 1910 Genetics | Boston, MA | Computational chemistry platform to develop small molecule therapeutics |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| , | ||
| , | Acquired by Bruker, Sep 2020 | |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Model Medicines | La Jolla, CA | AI Drug Discovery |
| , | Renamed Constant Therapeutics, Jan 2019 | |
| , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 | |
| , | Part of IntegenX | |
| , | No employees, no real info, Feb 2022 | |
| Partner Therapeutics | Lexington, MA | Biologics |
| , | CEO was gone in 2010, still showing on company website in 2015 | |
| |
Chessington, UK | ACROBiosystems | Delivering solutions such as proteins, antibodies, kits, GMP-grade reagents, and custom services to overcome challenges from discovery to the clinic. |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| , | ||
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| CQ Medical | Coralville, IA | Positioning, Radiation Devices |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| , | Acquired by Dynasil, Mar 2005 | |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| , | Renamed ATON | |
| , | Website disappeared, no news | |
| , | Website down Jun 2021 - Oct 2021 | |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| , | Website down Aug 2024 - Jan 2025 | |
| OptiNose | Yardley, PA | Drug delivery platform |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| , | Merged with Cato Research, Oct 2019 | |
| , | No activity 2015-2022, no employees on LI | |
| DDi | Singapore, Singapore | Clinical Software |
| Bluegrass Vascular | San Antonio, TX | Vascular access system |
| , | Bought by Boston Scientific, Jan 1997 | |
| , | ||
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| , | Now Selventa | |
| , | Acquired by Caliper Life Sciences, Oct 2005, $22M | |
| , | Website down Mar 2024 - Jul 2024 | |
| , | ||
| , | Acquired by Stryker, Sep 2010 | |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| , | ||
| iPSirius | Paris, France | iPSC-based Immunotherapy |
| , | Bought by Corixa, Oct 2000 | |
| , | Shut down | |
| , | Website down Jan 2022 - Jul 2022 | |
| ALX Oncology | South SF, CA | Immuno-oncology |
| , | Merged into cmbio | |
| , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX | |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Teikoku Pharma, May 2009 | |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| , | Shut down Feb 2020 | |
| , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed | |
| , | Website gone Dec 2015 | |
| , | All products acquired as of Nov 2020 | |
| , | Dissolved, Sep 2016 | |
| , | Winding down Mar 2024 | |
| , | Acquired by BASF 2010 | |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| , | Website down Jun 2021 - Dec 2021 | |
| Amicoat | Asker, Norway | Biofilm Prevention with Antimicrobial Coatings |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| , | Acquired Amplia Therapeutics, took its name | |
| , | Bought by OSI pharmaceuticals, Apr 2005 | |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Elevian | Newton, MA | Blood components to fight aging |
| , | Renamed Full Circles Therapeutics | |
| Norgine | Hengoed, UK | Specialty Pharma |
| , | Shut down Nov 2009 | |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| , | Acquired by Aldevron, Jan 2022 | |
| , | Website gone Feb 2024 - Jun 2024 | |
| , | Acquired by Boston Scientific, Jun 2019, $465M | |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| , | Chapter 11 bankruptcy, Apr 2019 | |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| , | ||
| , | Acquired by Martindale Pharma, Jul 2016 | |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 | |
| , | Website down Oct 2021 - Jan 2022; President gone mid 2021 | |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products | |
| , | Bought by Novartis 2008, Closed 2010 | |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| , | Acquired by Merck, May 2006, $80M | |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| , | Closed 2006? | |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| , | Website down May 2022 - Oct 2022 | |
| , | Acquired by Intus Bio, Jun 2023 | |
| , | Renamed 4D Pharma Research | |
| , | Website taken over, Jul 2014 | |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| , | Website down Apr 2023 - Sep 2023 | |
| , | Renamed Rentschler Biopharma | |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Nugget Scientific | Houston, TX | Liquid Handling |
| , | Renamed G&L Scientifc | |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| , | Website down Feb 2023 - Jul 2023 | |
| , | Renamed Abcepta, 2019 | |
| , | Website gone Jun 2023 - Sep 2023 | |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| , | Changed name to Adaptive Biotechnologies, Jan 2012 | |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Zynex Medical | Englewood, CO | Medical Devices |
| , | Renamed Luma Therapeutics, Apr 2018 | |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| , | Gone | |
| , | Merged with F-star, Jul 2020 | |
| , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 | |
| , | Acquired by Alkermes, Nov 2019, up to $950M | |
| , | Renamed Amplified Therapeutics, Mar 2023 | |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| MediWound | Yavne, Israel | Wound & Burn Care |
| , | Dissolved Sep 2018 | |
| , | Shut down Nov 2024 | |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| , | ||
| , | Renamed Abilita Therapeutics, Jun 2023 | |
| , | CEO has another job, doesn't seem serious | |
| , | Bought by Sangamo, Oct 2018, $84M | |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Acutus Medical | Carlsbad, CA | Complex Cardiac Arrhythmias Diagnostics |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 | |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| , | Merged into Sumika Chemical Analysis Services, Oct 2023 | |
| Neuron23 | South SF, CA | AI-drug discovery |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Curia | Albany, NY | Contract Research, Development, Manufacturing |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Shut down Apr 2024 | |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| , | ||
| , | Website gone Mar 2018 | |
| , | Assets purchased by Foxx Life Sciences, 2011 | |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| , | No reports filed 2018 thru Aug 2021 | |
| , | Acquired by Malvern Panalytical, Jan 2022 | |
| Takara Bio USA | San Jose, CA | Lab products |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| , | Acquired by DJO, Jan 2021 | |
| , | Acquired by Meda Aug 2007, $767M | |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| , | Acquired by Infinity Laboratories | |
| , | Website gone Feb 2019, No employees Apr 2019 | |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| , | Website down Jul 2022 - Nov 2022 | |
| , | Website Gone | |
| , | Bought by Pfizer, Jul 2019, $11.4B | |
| , | Shell acquired Dec 2023 | |
| , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 | |
| , | Rebranded as Singota Solutions, Jul 2016 | |
| , | Website gone Oct 2018; Presumed Gone | |
| , | Renamed NuGenerex Immuno-Oncology, Mar 2020 | |
| , | ||
| AliveDx | Eysins, Switzerland | Diagnostics |
| , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 | |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| , | Renamed Virios Therapeutics, Aug 2020 | |
| , | Appears to now be NuSirt Biopharma | |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| , | Website Gone, Dec 2016 | |
| , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 | |
| Biocodex | Gentilly, France | Microbiota Treatments |
| , | Acquired by Nicox, Oct 2014, $120M | |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| , | Website down Jul 2021 - Dec 2021 | |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| , | Website down Nov 2018, no longer registered with CA | |
| Ergomed | Prague, Czech Republic | Clinical Research |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| Noucor Health | Barcelona, Spain | Small Molecules |
| , | Bankrupt, Jul 2009 | |
| , | Acquired by Nutriband, Apr 2018 | |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| , | Website down Sep 2020 - Mar 2021 | |
| Polyrizon | Raanana, Israel | Nasal Drug Delivery |
| , | ||
| , | ||
| , | Acquired by Quidel, $10+milestones, May 2013 | |
| Obulytix | Gent, Belgium | Phage lysin development |
| , | Website Gone | |
| , | Not registered as business in CA Mar 2020 - Apr 2020 | |
| MindRank | Shanghai, China | AI Drug Discovery |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| , | Liqudiating Jan 2023 | |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| , | Website redirecting Dec 2023 - May 2024 | |
| , | Shut Down Oct 2023 | |
| Pelican BioThermal | Maple Grove, MN | Temperature Controlled Packaging |
| , | Acquired by Neurolign, Oct 2019 | |
| , | Changed name to Strategia Therapeutics, Apr 2015 | |
| , | Bought by UCB, Apr 2020, $2.1B | |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| , | Renamed MIP Discovery, Jun 2022 | |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Abselion | Cambridge, UK | Biologics Quantification |
| , | ||
| Repligen | Waltham, MA | Protein Manufacturing |
| , | Acquired by PerkinElmer, Apr 2019 | |
| , | Acquired by Introgen Therapeutics, Oct 2004 | |
| , | Bankrupt, 2013 | |
| , | Merged with Diffusion Pharmaceuticals, Dec 2015 | |
| , | Pivoted to be CRO, CMO and operates under Avid bioservices now | |
| CYTOO | Cambridge, MA | High Content Screening |
| , | Renamed Ichor Life Sciences | |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| , | Website Gone 12-10-13, No longer a tenant at last known office | |
| , | Merged with Diversa to become Verenium | |
| , | ||
| Satellite Bio | Watertown, MA | Implantable satellite organs |
| , | Gone late 2023 | |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| , | Renamed Blue Water Biotech, Apr 2023 | |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| , | Website down Jan 2021 - May 2021 | |
| , | Website down Feb 2022 - Jul 2022 | |
| , | Website down Jan 2025, no FL busienss registration, no employees | |
| , | Acquired by IPCA Pharmaceutical, Jan 2018 | |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| , | Acquired by Aratana Therapeutics, Jan 2014 | |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| , | Gone | |
| , | Gone | |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| iotaMotion | Iowa City, IA | Cochlear Implant Insertion Robots |
| , | Renamed Asensus Surgical, Feb 2021 | |
| , | Acquired by PhotoMedex, Mar 2005 | |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| , | ||
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| , | Acquired by Charles River, Jun 2016 | |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 | |
| , | Acquired by Thoratec, Jul 2014 | |
| , | Virtual/Shell Company since about 2010 | |
| , | Website down Mar 2024 - Aug 2024 | |
| , | Shut down 2014 | |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Aquyre Biosciences | Paris, France | Biopsy Imaging |
| CaSRevolution | Milan, Italy | Alzheimer's Treatment |
| Neukio Biotherapeutics | Shanghai, China | CAR-T Cell Therapy |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| , | Acquired by Areva, Oct 2011 | |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| , | Website under construction Mar 2020 - Mar 2021 | |
| , | Chapter 11 Bankruptcy, Sep 2023 | |
| , | Website gone, Mar 2019; Never a registered CA business | |
| Massive Bio | New York, NY | Oncology Clinical Trials |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| , | Renamed CynapseDx, Oct 2016 | |
| DELFI Diagnostics | Baltimore, MD | Cancer Diagnostics |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| , | Shut down Jan 2021 | |
| Hutchmed | Hong Kong, China | Oral drugs |
| Accellacare | Winston-Salem, NC | Clinical Research |
| , | Now CMC Biologics | |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Acumed | Hampshire , UK | Medical Implants |
| Orthogonal LLC | Chicago, IL | Medical device software |
| , | Assets Acquired by Shionogi | |
| Canfield Scientific | Ultrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Novozymes | Bangalore, India | Enzymes |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| , | Website gone jan 2020 | |
| , | ||
| , | Acquired by Almirall, up to $400M | |
| , | ||
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| MSD | Carlow, Ireland | Vaccines |
| , | Acquired by Phibro Animal Health, Jan 2016 | |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| Pharming Group | Leiden, Netherlands | Biologics |
| , | Shut down per Linkedin page, likely Jul 2023 | |
| Charles River Laboratories | Stone Ridge, NY | Research Animal Models and Preclinical Research |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| , | Merged with Quintiles, May 2016 | |
| , | Acquired by Data Center Company for ticker | |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| , | Merged with NowDx, Apr 2023 | |
| , | Website down Jul 2021 - Nov 2021 | |
| , | Shut down Feb 2019 | |
| , | Shut down 2021; Oxford spinout | |
| Veracyte | South SF, CA | Cytology Diagnostics |
| , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 | |
| , | Renamed Genkyotex, Feb 2017 | |
| , | No updates since 2014 | |
| , | Renamed Avivo BioOptics | |
| , | Website gone Apr 2020 - Oct 2020 | |
| Pieris Pharmaceuticals | Hallbergmoos, Germany | Modified Anticalins |
| , | Reverse Merged into Pernix Therapeutics, Mar 2010 | |
| , | Renamed Tozaro, Aug 2024 | |
| , | Acquired by QPS, Jan 2012 | |
| , | Bough by Yifan Pharmaceutical, Aug 2018 | |
| , | Acquired by Catalyst Clinical Research, Jul 2023 | |
| , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M | |
| Toleranzia | Gothenburg, Sweden | Tolerogenic cell therapy for myasthenia gravis |
| , | Merged with Scilex, Mar 2019 | |
| , | Acquired by BMS 2012, $2.5B | |
| , | Bought by LabCorp 2002 | |
| , | Acquired by Caldera Medical, 2016 | |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| HanX Biopharmaceuticals | , | |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| , | Only real employee now full-time at another company | |
| , | Acquired by Antigenics, Aug 2000, $40M | |
| , | Acquired by Biomarin Jan 2013 | |
| Jubilant Cadista | Salisbury, MD | Fully Integrated Contract Research, Generics |
| , | folded into Nanobiotix | |
| Progyny | New York, NY | IVF products |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| , | Acquired by UCB, Mar 2022, $1.9B | |
| , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories | |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| , | Merged with Cambium, Apr 2024 | |
| , | No website May 2023 - Dec 2024 | |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Scarab Genomics | Madison, WI | Cells, DNA Analysis Supplies, Cloning Supplies |
| , | Website down Dec 2021 - Apr 2022 | |
| , | ||
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| , | Renamed Spirovant Sciences | |
| , | Ancient website Dec 2020 | |
| DeepLife | Vernon, France | Cellular Digital Twins |
| , | Acquired by Valeant Feb 2014 | |
| BRAND | Wertheim, Germany | Liquid Handling |
| , | Acquired by The Medicines Company, Dec 2012 | |
| , | Shut Down Jun 2022 | |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| , | Acquired by WCG, Mar 2018 | |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| , | Renamed Heart Tronics | |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Novozymes | Salem, VA | Enzymes, Biologic Reagents |
| , | ||
| , | Website down Feb 2021 - Aug 2021 | |
| , | Changed name to Assertio Therapeutics, Aug 2018 | |
| , | Website down Aug 2023 - Apr 2024 | |
| , | Part of Medical Center, Jun 2023 | |
| Processa Pharmaceuticals | Hanover, MD | Small Molecule |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| , | Acquired by Kala Pharmaceuticals, Nov 2021 | |
| , | Acquired by VGX Pharmaceuticals, 2007 | |
| , | Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 | |
| , | Bought by Certara | |
| , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals | |
| , | Bought by Amgen, Jul 2002, $16B | |
| Abbott | Princeton, NJ | Diagnostics |
| Veramed | London, UK | Biostatistics and programming services |
| miDiagnostics | Heverlee , Belgium | Diagnostics |
| , | Acquired by Quanterix, Jan 2018 | |
| , | Sold off products Apr 2019; Dr. Reddy's subsidiary | |
| , | Renamed Comera Life Sciences, Jan 2022 | |
| , | Restructured, renamed PharmaRoth Labs, Jul 2012 | |
| , | Merged with Insys Therapeutics | |
| , | Renamed Atlas Spine | |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| , | Website down Feb 2021 - Aug 2021 | |
| , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 | |
| , | Renamed Myllia, Apr 2022 | |
| , | Gone 2019 | |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| , | Website taken over by massager sales | |
| , | Renamed PLD Pharma Services | |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| PHIX Genomics | Manila, Phillippines | Clinical Genomic Diagnostics |
| Celerion | West Conshohocken, PA | Clinical Research |
| Orthofix International | Lewisville, TX | Medical Devices |
| , | Renamed Five Star Products | |
| , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 | |
| HydroCision | North Billerica, MA | Saline Jet Device |
| , | ||
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| , | Merged into Centessa Pharmaceticals | |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| , | ||
| , | Merged with Onconova to become Traws Pharma, Apr 2024 | |
| , | Merged with Tokai Pharmaceuticals, May 2017 | |
| , | Seems inactive, Aug 2023 | |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| , | Assets acquired by Novigenix, Feb 2015 | |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| Zumutor Biologics | Cambridge, MA | Biologics |
| , | Website down Jun 2023 - Dec 2023 | |
| ErVimmune | Lyon, France | Cancer Vaccines |
| Biocoat | Horsham, PA | Medical Device Coatings |
| , | ||
| , | Bankrupt, May 2022 | |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| , | Renamed Totus Medicines, Dec 2020 | |
| , | Acquired by Galapagos, Jul 2019 | |
| , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 | |
| SDIX | Newark, DE | Diagnostics |
| Ona Therapeutics | Barcelona, Spain | Cancer Therapies |
| Novarad | Provo, UT | Imaging Software and Technology |
| PhotoniCare | Champaign, IL | Optical Coherence Tomography for Ear Examination |
| , | Website gone Jun 2022 | |
| , | Assets acquired by CubeDx, Jul 2015 | |
| Domainex | Essex, UK | Drug Discovery Services |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| , | Bought by Sebela Pharmaceuticals, May 2018 | |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| , | Acquired by Gilead, Oct 2006, $2.5B | |
| , | Renamed Vast Therapeutics | |
| , | Shut down Jan 2021 | |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| , | Assets acquired by SpectraScience, Feb 2016 | |
| , | Acquired by ReproCell, 2014 | |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| , | Acquired by DermBiont, Oct 2020 | |
| , | New business at address Feb 2025; Business filings late Apr 2023 - Feb 2025; co-located with Escend Pharma | |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals | |
| AbVacc | Rockville, MD | Vaccines & Immunotherapies |
| , | Acquired by Inotiv, Jan 2022, $56M | |
| , | Website down Oct 2020 - Mar 2021 | |
| , | No updates/info 2013-2022 | |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| , | Renamed Cue Biopharma, Nov 2016 | |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| , | Acquired by IRIS International, Aug 2010 | |
| , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg | |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Spring Discovery | San Carlos, CA | AI Image Analysis |
| , | Bought by Amicus Therapeutics, Sep 2018, $100M | |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| , | Website down Dec 2023 - May 2024 | |
| , | Founded as Eisai subsidiary | |
| , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M | |
| , | ||
| , | Owned by Sanofi, Acquired by Valeant Jul 2011 | |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences | |
| , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 | |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| Expansion Therapeutics | Waltham, MA | RNA Targeted Small Molecules |
| , | Acquired by Piramal, Aug 2016, $53M | |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| , | Bought by Boehringer Ingelheim, Jul 2012 | |
| Almirall | Barcelona, Spain | Small Molecules |
| , | Renamed TNF Pharmaceuticals, Jul 2024 | |
| , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company | |
| , | Acquired by Elorac Pharmaceuticals, Apr 2016 | |
| , | Acquired by J&J Nov 2014, $1.75B | |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| GenSensor | Nantes, France | Process Analytical Technology |
| , | Seem gone, Jun 2021 | |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| , | Website gone, one employee after 17 years | |
| , | No info since 2013, seems gone | |
| Vivacy | Archamps, France | Aesthetic Medicine |
| , | ||
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| , | Changed name to Aviragen Therapeutics, Apr 2016 | |
| , | Renamed Aclarion | |
| BGI | Copenhagen, Denmark | Diagnostics |
| , | Shut down, Feb 2015 | |
| Ipsen | Dublin, Ireland | Small Molecules |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals | |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| , | Acquired by Alcon, Mar 2019, $285M | |
| Innovacell Biotechnologie | Innsbruck, Austria | Cell Therapy for Incontinence |
| , | Acquired by J&J, Apr 2017 - Became part of Cerenovus | |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| , | Renamed DNA Analytics, Sep 2020 | |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| , | ||
| , | Merged with Vectalys, May 2018, became Flash Therapeutics | |
| , | ||
| , | Seems inactive, Apr 2024 | |
| , | Shut down Dec 2021 | |
| Roche | Basel, Switzerland | Diagnostics |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| , | Bought by GSK, 2005; closed 2006 | |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| , | Website under construction, Jun 2021 - Dec 2021 | |
| , | 2011 startup, no website Jun 2019 | |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 | |
| , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M | |
| Lavipharm | East Windsor, NJ | Small molecules |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| , | Changed name to Apexian Pharmaceuticals, Oct 2016 | |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| , | Acquired by Crown Bioscience, Mar 2016 | |
| , | Bankrupt, location sold | |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| , | Merged with mdRNA, became Marina Biotech 2010 | |
| , | Rolled into Johnson & Johnson MedTech, Sep 2024 | |
| , | ||
| , | Acquired by Genzyme, Oct 2007, $345M | |
| Aranscia | Houston, TX | Diagnostic Software |
| , | Website down Jan 2021 - May 2021 | |
| Gene Therapy Research Institute (GTRI) | Kanagawa, Japan | Gene Therapy |
| , | Renamed Elevaris Medial Devices, Jan 2025 | |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| , | Folded into nFerence | |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| iWel | Exton, PA | Glucose Meters |
| , | Website gone Nov 2022 | |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| , | Website down Aug 2024, no news since Jul 2019 | |
| , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 | |
| , | Bought by Merck Jan 2015 | |
| , | Website down Jan 2022 - Jul 2022 | |
| Eargo | San Jose, CA | Hearing Aids |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| , | Created by Macrogen, Brought back into Macrogen, 2016 | |
| , | Acquired by PCI Pharma Services, Dec 2021 | |
| , | Website gone Apr 2022, no employees | |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| , | Renamed Canexia Health, Jul 2020 | |
| HAON Life Sciences | Dublin, Ireland | Cell Therapy Platform |
| WuXi Apptec | Philadelphia, PA | Contract Biologics, Medical Devices |
| , | CEO gone Aug 2022; Website gone Oct 2022 | |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| , | Renamed BlinkBio | |
| Prevail Therapeutics | New York, NY | AAV-based gene therapies |
| Tome Biosciences | Watertown, MA | Programmable Gene Insertion |
| , | Changed name to Vericel, Oct 2014 | |
| , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones | |
| , | Renamed Zeda, Mar 2023 | |
| , | Acquired by Charles River, Aug 2017 | |
| New Zealand Pharmaceuticals | Palmerston North, New Zealand | Pharmaceutical ingredients and intermediates |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| , | Defunct | |
| OmniGuide | Billerica, MA | Surgical technology |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Shut down 2020 | |
| , | Renamed Preora Healthcare, Oct 2017 | |
| Microbiotix | Worcester, MA | Small Molecules |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| , | Acquired by Shire, Apr 2007, $2.6B | |
| , | ||
| , | Acquired by Centessa Pharmaceuticals | |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| , | Bought by Nitto Denko | |
| , | ||
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 | |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| , | Merged with Jaguar Animal Health, Jul 2017. | |
| Trukera Medical | Temecula, CA | Dry eye diagnostic |
| LumiraDx | London, UK | Diagnostic Platform |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| , | Renamed San Rocco Therapeutics, 2020 | |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| , | Bought by biotechne, Mar 2016; Spun out of Berkeley | |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| , | Shut down July 2012 | |
| , | Seems gone Aug 2022 | |
| Mallinckrodt | Dublin, Ireland | Specialty, Generics, Imaging Agents |
| , | Website not updated since 2007. AOL email | |
| , | Gone | |
| , | Acquired by Lantheus, Jun 2020 | |
| Medochemie | Limassol, Cyprus | Generics |
| , | Website gone Feb 2022; Product rights were sold | |
| Imagene | Tel Aviv, Israel | Image-based Biomarker Detection |
| , | ||
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| , | ||
| , | Seems gone | |
| , | Acquired by Erbe Elektromedizin, Apr 2021 | |
| , | Acquired by Boston Scientific, May 2017, $435M | |
| , | Assets acquired by Momenta | |
| , | No info, no website, Nov 2018 - Feb 2024 | |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Eyenovia | New York, NY | Ocular Drug Delivery Technology |
| Biosceptre | Norwest, Australia | Therapeutics & Diagnostics targeting nf-P2X7 |
| , | Liquidated | |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| , | Website from 2010 as of Feb 2025, emails bouncing | |
| , | Acquired by I'rom Group | |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| , | Now PathoGenetix | |
| , | Acquired by Prestige Brands, Apr 2014, $650M | |
| , | Acquired by PPD, Apr 2009 | |
| , | Now C3J Therapeutics | |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| , | No info Jun 2015, Oct 2016, Dec 2019 | |
| , | Bankrupt, Jul 2012 | |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| , | Gone, Oct 2022 | |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| , | Acquired by Johnson & Johnson, Nov 2023, $400M | |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| , | Seems gone Nov 2022 | |
| , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones | |
| , | Website taken over Jan 2024 | |
| , | Renamed AI Therapeutics | |
| , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones | |
| , | ||
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| , | Acquired Cellix and now operating under that name it seems, Jan 2019 | |
| , | Website down Sep 2021 - Jan 2022 | |
| , | Website down Jan 2024 - Jul 2024 | |
| , | Acquired by Anika Therapeutics, Feb 2020, $100M | |
| Pro-Lab Diagnostics | Round Rock, TX | Clinical & Molecular Diagnostics |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| , | Licensed all IP permanently to Biogen, Feb 2017 | |
| Piramal | Mulund West, India | Small Molecules |
| , | Now Evelo Biosciences | |
| , | Website down Jan 2020 - Jun 2020 | |
| Caris Life Sciences | Irving, TX | Diagnostics |
| , | Renamed zPREDICTA | |
| , | Merged with Upjohn, renamed Viatris | |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| , | Website down Jan 2024 - Jul 2024 | |
| , | Gone Mar 2016 | |
| SeNostic | Hannover, Germany | Diagnostics for Neurodegeneration |
| , | Renamed Adhesion Therapeutics, May 2024 | |
| , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox | |
| , | Seems pulled into Roivant, Sep 2022 | |
| Innoplexus | Hinjewadi, India | AI for Drug Discovery |
| , | ||
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Xybion | Princeton, NJ | Cloud LIMS, Quality |
| , | Acquired by CEND Therapeutics, Sep 2020 | |
| , | Website gone, Company Presumed gone | |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| , | Acquired by Emmes, Dec 2020 | |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| |
Belfast, UK | ARC Regulatory is a specialist regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 | |
| , | Bought by Merck, Sep 2017, $150M + $453 Milestones | |
| , | Renamed Scaffold Biologics, Mar 2018 | |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| , | Renamed First Light Diagnostics, Dec 2018 | |
| , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 | |
| , | Bankrupt, May 2024 | |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| , | Website taken over Feb 2025 | |
| , | Changed name to Levolta Pharmaceuticals | |
| , | Website down Feb 2020 - Aug 2020 | |
| , | Acquired by Charles River Labs, Jan 2020, $380M | |
| , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares | |
| , | Website down May 2023 - Dec 2023 | |
| , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology | |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| , | Acquired by P95, Jul 2024 | |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Getinge | Tournefeuille, France | Medical Technology |
| Kurin | San Diego, CA | Blood Collection Technology |
| , | ||
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| , | Acquired by mAbxience, Jun 2014 | |
| MicroPort | Clamart, France | Medical Devices |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| , | ||
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| Gilead | Edmonton, AB | Small Molecules |
| , | Renamed Averna Therapeutics, Jan 2025 | |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Echelon Biosciences, Apr 2014 | |
| Isolere Bio | Research Triangle Park, NC | Chromatography-free solutions for the purification of biological therapeutics |
| , | Renamed Arbor Biosciences | |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| , | Bought by Fountain Pharma, Jan 2017 | |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Celerion | Vienna, Austria | Clinical Research |
| , | Acquired by DJO, Apr 2021 | |
| Eurogentec | Seraing, Belgium | Biologics |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Jetequip | Boucherville, QC | Fluid Handling |
| , | Acquired by Life Technologies, Jan 2008 | |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| , | Renamed Theratome Bio | |
| , | Sold off product to Acorda, Folded? | |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Lindus Health | London, UK | CRO |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| , | Out of Money 2010 | |
| , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M | |
| Curevo Vaccine | Bothell, WA | Vaccines |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Bora CDMO | Tainan City, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Eccogene | Shanghai, China | Small Molecules |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| , | Website gone Jun 2022 - Oct 2022 | |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Valitor | Berkeley, CA | Protein therapeutics |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| , | Merged into Eppendorf | |
| Semaphore Solutions | Victoria, BC | Lab Software |
| , | Fully acquired by IQVIA, Apr 2021 | |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| , | Acquired by Catalent, Sep 2016 | |
| , | Acquired by Concentra Biosciences, May 2023 | |
| , | Acquired by Sino Biological, Oct 2023 | |
| Alexion Pharmaceuticals | New Haven, CT | Biologics |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| , | Website down Jun 2020 - Jan 2021 | |
| , | Acquired Accumetrics, Rebranded as Accriva Diagnostics | |
| , | Merged with Aenova | |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Robeauté | Paris, France | Neurosurgical Robotics |
| , | Shut down by 2014 | |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems | |
| , | Acquired by Cortexyme, May 2022 | |
| , | ||
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| , | Acquired by ALS Group USA, Feb 2019 | |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| , | Bought by Cornerstone Therapeutics 2012 | |
| , | ||
| , | Renamed BobcatBio, Jan 2025 | |
| , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 | |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| , | Acquired by AMRI, Jul 2014 | |
| , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial | |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| , | Acquired by Adare Pharma Solutions, Dec 2021 | |
| , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M | |
| , | ||
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| , | Bought by Boehringer Ingelheim, Sep 2018, $244M | |
| , | Dissolved | |
| , | Website down Jan 2021 - May 2021 | |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| , | Renamed ProKidney, Dec 2020 | |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| , | Gone Jun 2021 | |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| , | Shutting down late 2023 | |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| , | Changed name to Activate Immunotherapy, Aug 2016 | |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| , | Acquired by Entelos, Aug 2007 | |
| Secura Bio | Las Vegas, NV | Acquisition & Worldwide Commercialization |
| Getinge | Getinge, Sweden | Medical Technology |
| Healogix | Doylestown, PA | Consulting |
| , | Merged with Oncotelic Apr 2019; fka Oxigene | |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Quantificare | Makati City, Philippines | Medical Imaging |
| , | Renamed BlueLight Therapeutics, Jun 2020 | |
| , | Acquired by Teleflex Medical | |
| , | Now Anacura | |
| IGM Biosciences | Mountain View, CA | Antibody Treatments |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 | |
| , | Gone 2018 | |
| , | Seems to have pivoted to data analytics; fka Transparency Life Sciences | |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| , | Website taken over by a church, Jan 2024 | |
| , | No website Aug 2020 - Jul 2024 | |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| , | ||
| Accellacare | Cary, NC | Clinical Research |
| , | Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones | |
| Medtronic | Shoreview, MN | Medical Devices |
| NovoMedix | San Diego, CA | Small molecules |
| , | Chapter 7 bankruptcy, Feb 2023 | |
| , | Renamed DMS Imaging | |
| , | Bought by Spark Therapeutics, Mar 2016, $15M | |
| Tecnimede | Lisbon, Portugal | Generics |
| , | ||
| , | Folded into IQVIA, Aug 2023 | |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Syros Pharmaceuticals | Cambridge, MA | Gene Regulation Drug Discovery Platform |
| , | Filed for bankruptcy, Jun 2013 | |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| , | ||
| , | Website taken over Sep 2020 | |
| , | Website not updated since 2008 | |
| , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 | |
| , | Renamed vTv Therapeutics | |
| , | Renamed Abveris | |
| , | Website down Feb 2024, never registered business | |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| SYNCROSOME | Marseille, France | Preclinical contract research |
| Terumo Medical | Elkton, MD | Medical Devices |
| , | Gone 2014? | |
| , | Bought by Celgene, Jan 2012, $350M | |
| , | Merged with Orgenesis Biotech | |
| , | Renamed General Proximity | |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 | |
| Spesana | Memphis, TN | Clinical Decision Software |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| , | ||
| Archimedic | West Chester, PA | Medical Device Consulting |
| , | Website suspended, Sep 2020 - Jan 2021 | |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| , | ||
| , | Merged into BioDuro, Nov 2015 | |
| , | Gone Jul 2013 | |
| , | ||
| , | Website down May 2022 - Jun 2022 | |
| , | Renamed Alnylam | |
| , | Renamed Averto Medical | |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| Humacyte | Durham, NC | Bioengineered Vessels |
| , | Gone 2010 | |
| , | ||
| , | Acquired by Invitae, Nov 2017 | |
| , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M | |
| MSD | Ballydine, Ireland | Small Molecules |
| , | Apparently sold all products | |
| , | Bought by Ethicon, Mar 2016 | |
| , | Website under construction Feb 2020 - Mar 2021 | |
| , | Merged into Millendo therapeutics, Dec 2018 | |
| Almac | Penicuik, UK | Pharmaceutical Services |
| , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones | |
| Xequel Bio | Mount Pleasant, SC | Peptide for Injury Healing |
| Ultivue | Cambridge, MA | Reagents, chemicals |
| Lupin | Goa, India | Generics |
| , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics | |
| Triangle Insights Group | Durham, NC | Consulting |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Pepper Bio | Boston, MA | Transomics drug discovery |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| , | Acquired by Leica Biosystems, Nov 2022 | |
| , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech | |
| Qualigen Therapeutics | Carlsbad, CA | Inhibitors |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| , | Website down Dec 2022 - Apr 2023 | |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| , | Renamed Minka Therapeutics, 2018 | |
| , | No news 2017 - Aug 2024 | |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| , | Funded in 2009, presumed defunct | |
| , | Acquired by Retroscreen Virology Group, Mar 2014 | |
| , | Acquired by Sanofi, Dec 2021 | |
| , | Merged into Certa Therapeutics | |
| Stago | Gennevilliers, France | Diagnostics |
| , | Bought by Cell Medica, Jul 2016 | |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| , | Gone Jan 2019 | |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| , | Acquired by Century Therapeutics, Jun 2020 | |
| , | Acquired by Vertex, Jun 2019, $245M | |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| , | Acquired by NeuroDiscovery, Feb 2013 | |
| , | Website redirecting to Nantoomics, Nov 2019 | |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| |
King of Prussia, PA | WuXi Biologics | Biologics & vaccines development services for antibodies & proteins from mammalian expression systems. |
| ABX -CRO advanced pharmaceutical services | Radeberg, Germany | Research Products |
| Akesobio | Zhongshan, China | Antibody Therapies |
| , | Acquired by Quotient Sciences, Feb 2021 | |
| , | Website Gone | |
| , | Renamed Eden Biologics, Feb 2021 | |
| , | ||
| , | Dissolved | |
| , | Website copyright 2006 as of Nov 2019 | |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Drug Farm | Jiashan, China | Using AI to discover genetic therapies |
| Charles River Laboratories | Malvern, PA | Research Animal Models and Preclinical Research |
| , | Merged into Lion Biotechnologies, 2013 | |
| , | Acquired by 3M, Feb 2007 | |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| , | Renamed Vantage Medtech | |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| , | Acquired by SillaJen, Nov 2013, up to $150M | |
| Eurofins CDMO | Mississauga, ON | Eurofins CDMO focuses on APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| , | Acquired by Syner-G BioPharma Group, Jan 2023 | |
| , | Gone Oct 2018 | |
| , | Renamed Cusabio Technology | |
| , | Renamed Qvin | |
| BIOPIX-T | Voutes, Greece | Molecular diagnostic device for rapid testing at the Point-of-Care |
| , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name | |
| , | Acquired by Heraeus, 2020 | |
| , | Assets sold to Nephrion, 2007 | |
| , | Acquired by Eli Lilly, Oct 2023 | |
| , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket | |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| , | Website down Sep 2022 - Feb 2023 | |
| , | Shut Down 2018? | |
| , | Shut down Aug 2020 | |
| Innovo Therapeutics | , | AI Drug Discovery |
| , | Shut down May 2019 | |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| , | Website down Apr 2024 - Aug 2024 | |
| , | Acquired by Sangamo, Aug 2013 | |
| , | Bought by Zavation, Sep 2018 | |
| , | Assets bought by Vermillion 2011 | |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| , | ||
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| , | Acquired by Lilly | |
| , | Website gone Aug 2019 | |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| Biomarker Strategies | Rockville, MD | Tumor Biomarker Testing Systems |
| , | Gone | |
| Cellics Therapeutics | San Diego, CA | Nanosponge Technology |
| , | Now KCR | |
| , | Merged into Affitech, May 2009 | |
| , | Renamed GT Biopharma | |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Veeda Clinical Research | Ahmedabad, India | Preclinical & Clinical Research |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 | |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| , | Shut down Jul 2023 | |
| , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 | |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| XtalPi | Shenzhen, China | AI Drug Design |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| , | Gone Feb 2018 | |
| , | Acquired by Halozyme, May 2022, $960M | |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| PolyGen Pharmaceuticals | Edgewood, NY | Generics |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| , | Rolled into Werfen | |
| , | Website down May 2021 - Sep 2021 | |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| , | Acquired by Merck, Feb 2021, $1.85B | |
| , | Assets acquired by Rebus Biosystems, Dec 2021 | |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| , | Changed name to Nemera, Jul 2014 | |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| , | Gone | |
| , | Gone; fka Molecular Diagnostics, Inc. | |
| , | Renamed MiNK Therapeutics, Aug 2021 | |
| Caidya | Raleigh, NC | Clinical Research Organization |
| , | Founded 2000 | |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| GeoVax | Smyrna, GA | Vaccines |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| , | Acquired by eurofins, Jan 2018 | |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| , | Bought by Sunovion, $430M, Aug 2012 | |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Stellartech Research | Milpitas, CA | Electronic device development |
| , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 | |
| , | ||
| , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 | |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| , | Acquired by TransEnterix, Sep 2015, $100M | |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| , | Renamed DirectSync Surgical | |
| Gradiant Bioconvergence | Seoul, Korea | Organoid-based target discovery, Biomaterials |
| , | Acquired by Charles River, Apr 2019, €448M | |
| ADC Therapeutics | London, UK | Antibody-drug conjugates |
| , | Possibly reincarnated as StemCell2MAX | |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| , | No website, trials started in 1999. Genzyme may have taken control of product | |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| , | Gone | |
| , | Renamed Solsys Medical | |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| Addex Therapeutics | Geneva, Switzerland | Allosteric modulators |
| , | Acquired by BMS, Jan 2024, $4.8B | |
| , | Website down Nov 2024 - Feb 2025, marked is closed on Google | |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| , | Gone Jun 2019 | |
| , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 | |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Mnemo Therapeutics | Paris, France | CAR-T Therapies |
| BiOneCure Therapeutics | Germantown, MD | Antibody-Drug Conjugates |
| , | Website down Dec 2023 - May 2024 | |
| preclinics | Potsdam, Germany | Contract Research |
| , | ||
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| , | Bought by Pfizer, Jul 2019, $340M + $470M milestones | |
| , | Changed name to Oxurion, Sep 2018 | |
| , | Changed name to Generation Bio, Nov 2017 | |
| , | Acquired by LivaNova, Dec 2017 | |
| , | Renamed Torrent Pharmaceuticals | |
| Amniotics | Lund, Sweden | Stem Cell Therapies |
| , | ||
| Opna Bio | South SF, CA | Novel oncology therapeutics |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| , | Renamed Ingenus Pharmaceuticals, 2019 | |
| Profluent | Berkeley, CA | AI Protein Creation |
| , | Acquired by Dendreon Pharmaceuticals, Nov 2003 | |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| , | Renamed Zerigo Health, Oct 2020 | |
| , | Renamed Piton Therapeutics, Jan 2023 | |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| , | Website lists an exec who left in 2002 as being active | |
| , | Merged into ANI Pharmaceuticals Jun 2013 | |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan City, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| |
Taipei, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Crown Bioscience | Taipei, Taiwan | Drug Development |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung City , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| HanchorBio | Taipei City, Taiwan | Fc-Based Designer Biologics |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| Pharmadax | New Taipei City, Taiwan | Generics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclincal, Toxicology and Pharmacology laboratory. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Teclison | Taipei, Taiwan | Cancer Therapies |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| TWi Pharmaceuticals | Taipei, Taiwan | High barrier generics |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Zai Lab | Taipei, Taiwan | Small Molecules |