Taiwan - Biotech Companies - Career Pages
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| Roche | Schlieren, Switzerland | Small Molecules |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Ufovax | , | Renamed Uvax Bio? |
| Indexus Biomedical | , | Shut down 2018 |
| Medreich | Bengaluru, India | CDMO |
| EndoStim | , | Shut down Jan 2020 |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Onyvax | , | Assets Apparently Acquired |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| Athlon Pharma | , | No news since 2006 lawsuit |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Divide and Conquer | , | Website gone Mar 2024 |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Enovalife | Paris, France | Biometrics and medical writing services |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| Neuronax | , | Renamed Axoltis Pharma |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| , | Renamed Create Medicines, Oct 2025 | |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Rechon Life Science | , | Ancient website Dec 2020 |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Boston Biokeys | , | Gone June 2017 |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| Chiromics | , | Website now a penny stock shill |
| BianoGMP | Gera, Germany | Oligonucleotides |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| GenoImmune | , | |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| , | Website under construction Dec 2024 - May 2026 | |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| , | Acquired by hVIVO, Jan 2025 | |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Pathwork Diagnostics | , | Closed 2013 |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| , | Website down Oct 2025 - Jan 2026 | |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| InxMed | Beijing, China | Oncology Treatments |
| Bracco | Monroe Township, NJ | Imaging |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Neose | , | Gone |
| TumorEnd | , | Website gone Feb 2019 |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| BalinBac Therapeutics | , | Gone 2018 |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Pharmaron | Coventry, RI | API Manufacturing |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| , | Website down Jan 2026 - May 2026 | |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Altair Therapeutics | , | Shut down Feb 2011 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Pharmatrope | , | Absurd website 2020-2023 |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| ImmuneMed | , | Shut Down |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
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Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Baxter | Marion, NC | Medication Delivery |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| SJ Pharma | , | Website gone, Nov 2018 |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Biotrin International | , | Renamed Diasorin? |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Pharmanovia | London, UK | Acquisition of Drugs |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Parabase Genomics | , | Presumed gone |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| Aves Labs | , | Now part of Antibodies Inc |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| Snorx | , | Renamed Zelegent, May 2015 |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| Optimata | , | Shut down May 2019 |
| Advanced Vision Science | , | |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| IGF Oncology | , | Shut down 2022 |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Nexus Genomics | , | Gone 2001 |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Oxitope | , | Shut Down Feb 2019 |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Waratah Pharmaceuticals | , | Gone 2007 |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| Califia Bio | , | Shut down May 2020 |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Sunho Biologics | Nanjing, China | Biologics |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Lupin | Somerset, NJ | Generics |
| QuantaBio | Beverly, MA | PCR equipment |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| pHion Therapeutics | , | Winding down Mar 2025 |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| MedinCell | Jacou, France | API Delivery Gel |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| , | Acquired by MasterControl, Mar 2025 | |
| , | Inactive May 2025 | |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| Evonik Industries | Lafayette, IN | API Manufacturing |
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Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| , | Acquired by Merck, May 2026, $6.67B | |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| , | Website down Dec 2025 - Apr 2026 | |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| Lysogene | , | Liquidating, Jan-May 2023 |
| , | Website down Dec 2025 - Apr 2026 | |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| TheraCoat | , | Renamed UroGen Pharma |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| Roche | Pleasanton, CA | Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| Inductive Bio | Virtual, US | Compound Optimization |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Signatur Biosciences | London, UK | PCR Platform |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| R2M Pharma | South SF, CA | Drug Development Services |
| Fortrea | Durham, NC | Clinical Research |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Envisagenics | New York, NY | Software-based drug discovery |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Evestra | San Antonio, TX | Women's Health |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| Koelis | Meylan, France | Prostate Biopsy System |
| AMRI | , | Renamed Curia, Jul 2021 |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| , | Acquired by Xoma, Nov 2025 | |
| Myoposity Therapeutics | , | Gone |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| , | Website down Jan 2026 - May 2026 | |
| , | mRNA Cell Therapy combo | |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| , | Acquired by Hologic, Jan 2025, $350M | |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Meissner | Camarillo, CA | Lab Systems |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| TRIFARMA | Chennai, India | APIs |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis la |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| PACT Pharma | , | Shut down Sep 2023 |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| , | Website down Aug 2025 - Jan 2026 | |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| , | Website down Jan 2026 - Mar 2026 | |
| FemtoVox | , | |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| AC Diagnostics | , | Website from 2004 |
| Cerebroscience | , | One employee, website gone |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
 |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| Sancilio | , | Now Micelle BioPharma |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Ciphergen | , | Now Vermillion |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| Calchan | , | Shut down Dec 2020 |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| hC Bioscience | , | Shut down Mar 2025 |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| , | Website down Jul 2025 - Jan 2026 | |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Boston Neurosciences | , | Website down Jun 2020 |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Birdotech | Shanghai, China | CDRMO |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Symansis | Timaru, New Zealand | Reagents |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| Septerna | South SF, CA | GPCR Drug Discovery |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| , | Shut down Nov 2025, Tempus acquired assets | |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| VitaCyte | Indianapolis, IN | Collagenase |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Avexxin | , | Rebranded as Coegin Pharma |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| , | Liquidated Jun 2025 | |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Xylo | Boulder, CO | Psychedelics |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Onkor Pharma | , | 10 year old company with no product or website |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Curefaktor Pharmaceuticals | , | Website Gone |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| Unigene Laboratories | , | Closed 2013 |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| , | Liquidating Feb 2025 | |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| , | Now PiSA USA | |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Diality | Irvine, CA | Hemodialysis System |
| icotec | Altstätten, Switzerland | Spinal Implants |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Defyrus | , | Website gone Nov 2017 |
| Formycon | Martinsried, Germany | Biosimilars |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| Ribocept | , | Defunct |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| algorithmRx | , | Now Venebio |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Genencor | , | Bought by DuPont |
| Baxter | Jayuya, PR | Medication Delivery |
| Plexanome | , | Gone 2018 |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| RFE Pharma | , | Gone 2019 |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| MIFCOR | , | Founders both gone Feb 2021 |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
 |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Lectus Therapeutics | , | Sold off product |
| Splice Histology | Worcester, MA | Histopathology Services |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| Italchimici | , | Acquired by Recordati, May 2016 |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| MantraPharma | Lévis, QC | Generics |
| Kurin | San Diego, CA | Blood Collection Technology |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| Synteract | , | Website down May 2022 - Oct 2022 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| Piramal | Mumbai, India | CDMO |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| Alfacell | , | Now Tamir Biotechnology |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Furong Biotech | , | |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Bayer | Mailand , Italy | Small Molecules |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| SelectX | , | Website hacked; No updates since 2011 |
| BioDatomics | , | Website gone Jan 2019 |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| Getinge | La Ciotat, France | Medical Technology |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
 |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Medtronic | Shoreview, MN | Medical Devices |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| Stryker | Mahwah, NJ | Medical Devices |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| Bluestar Genomics | , | Renamed ClearNote Health |
| Plureon | , | Website gone, one employee after 17 years |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
 |
Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| Elektrofi | Boston, MA | Biologics Formulation |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Pathfinder Cell Therapy | , | Gone 2016 |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| AptaIT | , | Website gone and for sale Nov 2019 |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Diverse Genomics | , | Website gone Jul 2020 |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Crown Bioscience | Beijing, China | Drug Development |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| , | Website down Nov 2025 - Apr 2026 | |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| , | Acquired by Collate, Aug 2025 | |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| SR Pharma | , | Now Silence Therapeutics |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| Prommune | , | |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| Genetic Technologies Group | , | Renamed geneType |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| Bracco | Milan, Italy | Imaging |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Santen | Tampere, Finland | Ophthalmics |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| , | Pivoted to blockchain, Sep 2025 | |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Gerinda Therapeutics | , | Gone 2009 |
| neoSurgical | , | Shut down 2017 |
| , | Website down, CEO gone Apr 2026 | |
 |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| CMC Biologics | , | Now part of AGC Biologics |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| ProPharma Group | Washington, DC | Consulting |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| , | Renamed BreezeBio, Feb 2026 | |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| , | Website down Dec 2025 - Apr 2026 | |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Bruker | Billerica, MA | Scientific Instruments |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| , | Website down Sep 2025 - Dec 2025 | |
| Argolight | Pessac, France | Microscopes |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| Iomai | , | Bought by Intercell 2008 |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Wepredic | Saint Gregorie, France | Cell Lines |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| Obexia | , | Gone |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| ReproSource | Marlborough, MA | Fertility Testing |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| Telis Bioscience | , | Renamed Alvea |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Genopis | , | Acquired by Wacker Feb 2021 |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| EMKinetics | , | Seems inactive Feb 2021 |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Apotech Consulting | London, UK | Life Science Consulting |
| PharmaDerm | , | Part of Sandoz |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| MGI Tech | Shenzhen, China | Sequencing |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| Trinity Drug Partners | , | Gone |
| CP Life Science | , | Split and became Medvacon |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| Allez Health | Carlsbad, CA | Biosensors |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| DDi | Basel, Switzerland | Clinical Software |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| TranS1 | , | Renamed Baxano Surgical |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| , | Renamed Trace Biosciences | |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| , | Shut down May 2025 | |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| GliaMed | , | Website copyright 2009, seems defunct |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Remo CRO | , | Seems to be rebranded as Supeira |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| CLCbio | , | Acquired by Qiagen, 2013 |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| Instapath | Houston , TX | Automated Digital Pathology |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| Anchen | , | Bought by Par Pharmaceutical |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| BioVolutions | , | Gone |
| Niowave | Lansing, MI | Radioisotopes |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Cellenion | Lyon, France | Single Cell Testing |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| , | Gone 2023, website taken over by a designer | |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
 |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| Axium Pharmaceuticals | , | Dissolved |
| MSD | Carlow, Ireland | Vaccines |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| PreciThera | , | Website taken over, Dec 2021 |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| Avatar Biotechnologies | , | Gone 2010 |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| Biovays | , | Website Gone |
| Creative Enzymes | Shirley, NY | Enzymes |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Trophea | , | Liquidated, Dec 2019 |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Santen | Osaka, Japan | Ophthalmics |
| Kegelbell | , | Shut down, Dec 2024 |
| CyberHeart | , | Acquired by Varian, May 2019 |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| LifeQual Pharmaceuticals | , | Website Gone |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| Avenir Pharma | , | No longer active |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Medley Genomics | , | Website for sale Feb 2021 |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Dharma Biomedical | , | Website gone Nov 2022 |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Align Technology | Tempe, AZ | Teeth alignment |
| ZyStor | , | Bought by BioMarin, closed |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| Neuraxpharm | Langenfeld, Germany | Generics |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| NovoKera | , | Merged into Longevity Biomedical |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| Digene | , | Merged with Qiagen |
 |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| Prochon Biotech | , | Acquired by Histogenics |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Photonion | Schwerin, Germany | Analytical Equipment |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| Santen | Emeryville, CA | Ophthalmics |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| Precision Virologics | , | Precision Virologics |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| Caidya | Raleigh, NC | Clinical Research Organization |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| Virapur | , | Acquired by Microbiologics, 2017 |
| STB Lifesaving Technologies | , | Website gone |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| Hookipa Biotech | , | Now Hookipa Pharma |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| Sonexa Therapeutics | , | Closed 2013 |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| Aixa Bio | Cambridge, MA | AI genomics |
| Medtronic | Mounds View, MN | Medical Devices |
| CereScan Corp | , | Renamed CereHealth |
| , | Website down Jun 2025 - Dec 2025 | |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| MiniMed | Northridge, CA | Diabetes Management |
| Genedata | Basel, Switzerland | Bioinformatics |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Metrohm | Riverview, FL | Lab Data Management Software |
 |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| Artificial | Palo Alto, CA | AI Lab Platform |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Aikium | Berkeley, CA | AI Drug Discovery |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| , | being Acquired by Chugai, Oct 2025 | |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| Vivid Genomics | , | Shut down Sep 2023 |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Catawba Research | Charlotte, NC | Clinical Research |
| Altasciences | Auxvasse, MO | Contract Research |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| , | Became part of Accelerator, Dec 2025 | |
| Epigene Labs | Paris, France | Data Integration Platform |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Protelight Pharmaceuticals | Jiangyin, China | Peptide and Small Molecules Therapies |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| AmplifyBio | , | Shut down Apr 2025 |
| T-Ray Science | , | Renamed Verisante |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| argenx | Boston, MA | Antibody therapies |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| CFL Biotech | , | Website gone Jul 2020 |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Life Analytics Group | , | Gone |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Ketal Biomedical | , | Gone |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| , | Website down Oct 2025 - Feb 2026 | |
| Helsinn | Iselin, NJ | Small Molecules |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| Omneuron | , | Closed |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Rezolute | Bend, OR | Biologics |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| CONMED | Utica, NY | Surgical, Medical Devices |
| Techne | , | Part of R&D Systems |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| Serentrix | , | Seems gone Apr 2022 |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| Stryker | San Jose, CA | Medical Devices |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Eyetech | , | Website Gone 6-16-12 |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Accellacare | Wilmington, NC | Clinical Research |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| , | Shut down Apr 2026 | |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| MakroCare | San Francisco, CA | Drug Development Partner |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Ventaleon | , | Shut down 2020 |
| Ossur | Irvine, CA | Orthopedic Devices |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| Avatar Medical | Paris, France | Surgical Visualization |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Oticon | Somerset, NJ | Hearing Aids |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| MindRank | Shanghai, China | AI Drug Discovery |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Genfit | Cambridge, MA | Drug Discovery |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Slainte Bioceuticals | , | Gone |
| Seraph Biosciences | Detroit, MI | POC Pathogen Detection |
| Beacle | , | Founder gone, no info |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Perceptive | Nottingham, UK | Medical Imaging |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| ASIT Biotech | , | Renamed DMS Imaging |
| Aplagen | , | No activity since 2008 |
| Vernacare | Blackwood, UK | Surgical Devices |
| RhinoCyte | , | Website moved to a marketing agency domain |
| , | Acquired by AbbVie, Aug 2025 | |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Universal Precision Instruments, Inc. | , | |
| , | Acquired by Sun Pharma, May 2025 | |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Celsis | , | Now AAIPharma |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| , | Gone Jan 2026 | |
| Progenika | , | Bought by Grifols |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| CatSci | Cardiff, UK | Contract Research |
| Scion NeuroStim | , | Presumed gone |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| , | Website down Jan 2026 - May 2026 | |
| Medice | Iserlohn, Germany | Small Molecules |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| Enzo Biochem | , | |
| |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| JAMP Pharma | Boucherville, QC | Generics |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Champions Biotechnology | , | Now Champions Oncology |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| FHC | Bowdoin, ME | Medical Devices |
| Cobalis | , | Basically Bust |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Camurus | Lund, Sweden | Specialty medicines |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Neocis | Miami, FL | Dental Surgery Robots |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Analogic | Peabody, MA | Medical Imaging |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| Curia | Bon-Encontre, France | Contract Development, Manufacturing |
| Eco Quest | , | Now Cynata Therapeutics |
| , | ||
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| , | Part of Evogene | |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Piramal | Digwal, India | CDMO |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Zai Lab | Suzhou, China | Small Molecules |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| Avomeen | , | Acquired by Element, Mar 2021 |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| , | Acquired by Waters, 2023 | |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| Micell Technologies | , | Seems shut down 2019 |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| Flen Pharma | , | Now Flen Health |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| 7TM Pharma | , | Gone |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| Facile Therapeutics | , | Shut down Dec 2021 |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| CTG Pharma | , | Gone |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| , | Website down Dec 2025 - Apr 2026 | |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Enterin | , | Website taken over Feb 2025 |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Chroma Medicine | , | |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| Securecell | Urdorf, Switzerland | Lab automation |
| , | Website taken over May 2026 | |
| , | Acquired by Immedica, Feb 2025 | |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Celerion | Tempe, AZ | Clinical Research |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| Cardima | , | Bankrupt Dec 2010 |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| SironRx | , | Website gone Jul 2015 |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| BioPointe Scientific | , | Subsumed into parent |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| InnoCare | Shanghai, China | Cancer Treatments |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| ACROBiosystems | Basel, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Roche | Mannheim, Germany | Diagnostics |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Pion | Billerica, MA | Dissolution Data |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| VB Spine | Leesburg, VA | Spinal Implants |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| ReactDx | Melbourne, FL | Wireless Monitors |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Medtronic | Cincinnati, OH | Medical Devices |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Nuvik Therapeutics | , | No website, very little info |
| Synfini | Menlo Park, CA | AI Drug Design |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Restek | Bellefonte, PA | LCGC Equipment |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Centocor | , | Renamed Janssen Biotech |
| Anergix | , | Shut down Mar 2009 |
| BaseCure Therapeutics | , | |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| OxyPharma | , | Website not updated in five years, emails bounced |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Purely Proteins | , | All employees gone, no info |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Roslin Cells | , | Renamed RoslinCT |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| Hologic | Newark, DE | Diagnostic, Imaging |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| iTherapeutics | , | Doubt they do anything |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| , | Website down Oct 2025 - Jan 2026 | |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
 |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| Catalyst Clinical Research | Raleigh, NC | Clinical research solutions to the global biopharmaceutical industry |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| Genomics PLC | Oxford, UK | Genomic algorithms |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Antibiotice | Iasi, Romania | Generics |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Synlab | Munich, Germany | Clinical Lab Services |
| Active Implants | , | Renamed NUsurface |
| Seeker Biologics | , | Shut down May 2023 |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| Medtronic | Jacksonville, FL | Medical Devices |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| Marpē Therapeutics | , | Professor sideline |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| Evoke Medical | , | Renamed DirectSync Surgical |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| , | Website taken over, Jan 2026 | |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| VistaMed | , | |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| Adroit Surgical | , | Defunct |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| Cell Biosciences | , | Now ProteinSimple |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| NanoSort | , | Renamed NanoCellect |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Olio Labs | San francisco, CA | Software to de-risk clinical trials |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Clario | Philadelphia, PA | Clinical Services |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| G1 Therapeutics | , | |
| Kerecis | Arlington, VA | Wound Healing |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| GNA Biosolutions | , | Now part of HP Health |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Genomica | , | Shut down Sep 2022 |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| , | Acquired by Certara, Oct 2024 | |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| TheoremDx | , | Bankrupt Feb 2020 |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| GeneDx | Stamford, CT | Genetic Data |
| Medtronic | Danvers, MA | Medical Devices |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| , | ||
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Curamir Therapeutics | , | Shut down 2020 |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Vodori | Chicago, IL | Commercial Content Software |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| Moximed | Fremont, CA | Joint treatment |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| , | Acquired by Paradigm Health, Jan 2023 | |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| , | Website down May 2025 - Dec 2025 | |
| Elona Pharmaceuticals | , | Gone |
| InsightRX | San Francisco, CA | Dosing Model |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| NeoVista | , | Gone 2011 |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| A2IDEA | , | Only employee left Jan 2024 |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Medelis | Thompson's Station, TN | Clinical Research |
| Novotech | Shanghai, China | Clinical Research |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| Immutics | , | Renamed TrueBinding |
| Northern Lipids | , | Renamed Transferra |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| EyeCyte | , | Gone 2014 |
| EnquBio | San Diego, CA | Contract Research & Services |
| AxoGlia Therapeutics | , | Ran out of money |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| , | Website down May 2025 - Dec 2025 | |
| Avontec | , | Gone |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| Vision Genomics | , | Website Gone, Jul 2016 |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Entelos | , | Bankrupt |
| Rho | Durham, NC | Clinical Research |
| Procertus | , | Website Gone, Apr 2016 |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| mAbRx | , | Gone |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| Parexel | Durham, NC | Clinical Research |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Convalife Pharmaceuticals | Shanghai, China | Oncology, viruses and aging treatments; bispecific antibodies, small molecules |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Alverix | , | Acquired by BD, Jan 2014 |
| Biocious Life Sciences | , | Now Agilent |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| StromaCyte | , | Small time, no info. Defunct |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Apgene Bio | , | Shut down Oct 2020 |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| Genmab | Plainsboro, NJ | Biologics |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| OraSure | Bethlehem, PA | Diagnostics |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Amigenics | , | Gone |
| RegenoCELL Therapeutics | , | Presumed gone |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| ICN Pharmaceuticals | , | Now Valeant |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| , | Website down Sep 2025 - Feb 2026 | |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| Dermagen | , | Website Gone, scammy sites with similar name |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| Vanquish Oncology | , | No news 2015-2021 |
| Viragen | , | Liquidated Oct 2007 |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Evogene | Rehovot, Israel | Computational Biology |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| FocalOne | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Nano Oncology | , | Gone |
| QInstruments | Jena, Germany | Lab Instruments |
| Nuredis | , | Shut Down Apr 2021 |
| Viral Genetics | , | Now VG Life Sciences |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| Scynexis | Jersey City, NJ | Small Molecules |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Azano Biotech | , | Now Sandia Biotech |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| BioChain | Newark, CA | Sample Preparation |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Lannett | Trevose, PA | Generic Small Molecules |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| ArgusEye | Linköping, Sweden | Biosensors |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| Novalar | , | Licensing agreement, essentially gone |
| TocopheRx | , | Gone before 2019 |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| SteriTech | Sligo, Ireland | Process Equipment |
| LianBio | , | Winding down Feb 2024 |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Carver Biosciences | , | |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Website down Jul 2025 - Oct 2025 | |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| , | Assets being sold off May 2026 | |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| CONMED | Largo, FL | Surgical, Medical Devices |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Sania Therapeutics | London, UK | CNS Treatments |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| ModeX Therapeutics | Weston, MA | Biologics |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Expression Patholgy | , | Now OncoPlexDx |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| BrainCells | , | Website gone Feb 2014 |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| Staburo | Munich, Germany | Clinical Services |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| , | Acquired by Xoma, Oct 2025 | |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| , | Acquired by InformedDNA, Mar 2025 | |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| AlloThera | , | Gone, 2018 |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| Satoris | , | Bought by Rules-Based Medicine |
| Wetlin Research Associates | , | Centerwatch only |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Advansta | San Jose, CA | Protein characterization products |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| ATON | Shanghai, China | CDMO |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| , | Acquired by Medicover, Apr 2026 | |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| ARTham Therapeutics | , | Shut Down late 2023 |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| Life Couriers | Munich, Germany | Diagnostics |
| TRIA Bioscience | , | Shut down Aug 2021 |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| Cholestech | , | Now Alere |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Microislet | , | Bankrupt 2008 |
| Chanelle Pharma | London, UK | Generics |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Valneva | Lyon, France | Antibody Discovery |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| Amorsus | , | Website Gone 8-30-13 |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| Akermin | , | Closed |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Hemadvance | , | Gone |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Qbiogene | , | No website. Fisher sells their products |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| Ho’ola Therapeutics | , | |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| , | Acquired by IMA Group, Oct 2025 | |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| X-Rx | , | Shut down Jun 2020 |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| CardioCreate | , | Shut Down Jun 2020 |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| |
Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Aimmune Therapeutics | , | |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| , | Acquired by Chiesi, Apr 2023 | |
| NeuroFx | , | Renamed Theratome Bio |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Angiomics | , | Product being sold by another company |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| SeqRight | , | Acquired by GE Apr 2012 |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| DesignMedix | , | Shut down Aug 2020 |
| Outset Medical | San Jose, CA | Dialysis Device |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| Teva | West Chester, PA | Small Molecules |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Biowest Therapeutics | , | Website Gone |
| Amakem | , | Website gone Dec 2015 |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| , | Redirecting to Siemens, Feb 2026 | |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Anesiva | , | Bankrupt 2010 |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Bicolor | Belfast, UK | Lab Assays |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Adela | Toronto, ON | Liquid Biopsy |
| Telephus Medical | , | Now Telephus Biosciences |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| , | Renamed Envue, Feb 2026 | |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| tte laboratories | , | Acquired by Transcat |
| SourceMDx | , | Assets Sold |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Neurophet | Seoul, Korea | AI-Image Processing |
| Curadev | Kent, UK | Immuno-oncology |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Getinge | Merrimack, NH | Medical Technology |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| BA Sciences | Morrisville, NC | Analytical Services |
| Aliquot Solutions | , | Shut down Oct 2024 |
| Elite Research Institute | , | Gone, May 2018 |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| NovaLead Pharma | Pune, India | Small Molecules |
| Theranos | , | Dissolving, Sep 2018 |
| preclinics | Eystrup, Germany | Contract Research |
| PRA International | , | Now PRA Health Sciences |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| , | Website down Oct 2025 - Jan 2026 | |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Phasiq | , | Website gone Jul 2018 |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Osteologix | , | Liquidated, Sep 2015 |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Indigene Pharmaceuticals | , | Gone 2012 |
| Eleven P15 | , | Shut down |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Karykion | , | Website outdated, doesn't seem serious |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Java Clinical | , | Website gone Jun 2019 |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Alms Therapeutics | , | Gone Jul 2022 |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| , | Website down May 2025 - Nov 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| QT Vascular | , | Website gone Jan 2024 |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| GeneSeek | , | Bought by Neogen |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Vaccibody | , | Renamed Nykode Therapeutics |
| , | Renamed Fareon, Feb 2025 | |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| BGI | Copenhagen, Denmark | Diagnostics |
| Cam Med | , | Renamed Qlibrium |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| CBM Biopharma | , | Shut down Nov 2020 |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| , | Merged with Cohance, May 2025 | |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| , | Acquired by Inizio, Dec 2025 | |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Mitokyne | , | Renamed Mitobridge |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| Novasecta | London, UK | Pharma Consultancy |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| RegeneraTEch | , | Renamed Regencor |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Novocell | , | Renamed Viacyte |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Librede | , | Acquired by Lygos, Jan 2020 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| Accellacare | Cary, NC | Clinical Research |
| bioRASI | Aventura, FL | Clinical Research |
 |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Virax Biolabs | London, UK | Viral test Kits |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| NeurAxon | , | No updates since 2008 |
| Acelyrin | , | Merged into Alumis, May 2025 |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| TamuroBio | , | Shut Down Jun 2024 |
| DyNAbind | , | Shut down Apr 2025 |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| Zivena | , | Gone |
| Pharming Group | Leiden, Netherlands | Biologics |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| REPROMEDIX | , | Gone 2012 |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| , | Website down Jan 2026 - May 2026 | |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Altus Biologics | , | Vertex Subsidiary |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| , | Acquired by Canoa, Aug 2019 | |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Nuventra Pharma Sciences | , | Now Allucent |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| American Stem Cell | , | Changed name to Targazyme |
| TeutoCell | , | Renamed Xell, 2014 |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| Esculon | , | Seems defunct, employees gone |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| Central Pharma | Bedford, UK | Filling, Packaging |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| OccuRx | , | Merged into Certa Therapeutics |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| , | Website down Dec 2025 - Apr 2026 | |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| Makefield Therapeutics | , | Website Gone |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| THORASYS | Montréal, QC | Lung Function Measurement |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| Vega Therapeutics | , | Part of Star Therapeutics |
| Elypta | Solna, Sweden | Liquid Biopsy |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Masy Systems | , | fka Masy Biosystems |
| Maccine | , | Gone |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Stelvio Oncology | , | Gone late 2019 |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
 |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Ovation.io | Portland, ME | LIMS |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| Parker BioConsulting | , | Sole employee is a professional board member |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Acumed | Beijing, China | Medical Implants |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| , | No news 2020 - Nov 2025 | |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| Combs Lab | , | Website gone Dec 2016 |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| LabTwin | , | Merged with Labforward |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| Celerion | Montreal, QC | Clinical Research |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| OFD Biopharma | Albany, OR | Lyophilization |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Biotium | Fremont, CA | Fluorescent Reagents |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| EndoLogic | , | Seems inactive, Aug 2023 |
| , | Acquired by QOL Medical, Nov 2025 | |
| , | Website down Jun 2025 - Dec 2025 | |
| Alan Laboratories | , | Website gone, Jan 2019 |
| Gensco Pharma | Doral, FL | Transdermals |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Genfit | Loos, France | Drug Discovery |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| Pfizer | Ringaskiddy, Ireland | API production |
| Aethox Therapeutics | London, UK | Inhibitors |
| Iproteos | , | Products now with Accure Therapeutics |
| ObsEva | , | Shut down Feb 2024 |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| Dynacare | , | Bought by LabCorp 2002 |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| QT Ultrasound | , | Renamed QT Imaging |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| , | Website down Jan 2026 - May 2026 | |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Iquum | , | Acquired by Roche, Apr 2014 |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Pharmaron | Ningbo, China | R&D Services |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Intercytex | , | Liquidated |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Barrier Therapeutics | , | Bought by Stiefel |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| IONETIX | Lansing, MI | Radiopharmaceutical |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| Tecomet | Wilmington, MA | Implant Components |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| SFS | Madrid, Spain | Clinical Research Organization |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| Zila | , | Bought by Tolmar, Jul 2009 |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| Boston Scientific | St. Paul, MN | Medical Devices |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| AesRx | , | Bought by Baxter, Jul 2014 |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| Bafna | Chennai, India | Generics |
| MacroPore | , | Gone |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| , | Acquired by Uniphar | |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| Baxter | Singapore, Singapore | Medication Delivery |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Revance | Nashville, TN | Movement Disorder Treatment |
| EuroAPI | Paris, France | API Production, CDMO |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| Strike Bio | , | Assets auction, Aug 2017 |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Recopharma | , | Seems gone |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| NexMed | , | Now Apricus Bio |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Cytomatrix | , | Gone, Jun 2013 |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| Metabogenix Technologies | , | Gone Sep 2015 |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| Frenova | Waltham, MA | Renal clinical research |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Tecnimede | Lisbon, Portugal | Generics |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
 |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Curis | Lexington, MA | Small Molecules |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| Recida Therapeutics | , | |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| Salvat | Miami, FL | Small Molecules |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Seer | Redwood City, CA | Early Detection |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| Synovex | , | Renamed Adheron Therapeutics |
| Lion TCR | Singapore, Singapore | T cell therapy |
| SereDigm | , | Gone Nov 2009 |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Bora Biologics | San Diego, CA | Contract Biologics |
| , | Renamed BTgen Bio, May 2026 | |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Phytomedics | , | Can't find info on it |
| Cala Health | San Mateo, CA | Neurological Device |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| Fonar | Melville, NY | Upright MRI |
| NinePoint Medical | , | Seems gone Sep 2020 |
| Global Cell Solutions | , | Gone Apr 2018 |
| Claritas Genomics | , | Closed Jan 2018 |
| Commence Bio | , | Gone 2018 |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| Verenium | , | Bought by BASF, Dec 2013 |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Automata | London, UK | Lab workflow automation platform |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| , | Website down Sep 2025 - Dec 2025 | |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| AuraSense Therapeutics | , | Renamed Exicure |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Calico | South SF, CA | Aging treatments |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Breathometer | , | Product didn’t work, pivoted |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Palingen | , | Renamed IGM Biosciences |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| Applied Molecular Genetics | , | Renamed Amgen |
| NeuMedics | , | Website taken over by massager sales |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Avenge Bio | , | Shut Down Jul 2024 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Synlogic | , | Shut down Sep 2024 |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
 |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| Nuvelution Pharma | , | Gone 2020 |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| Weave | St. Louis, MO | Regulatory Submission Consulting |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| , | Renamed Silthera, Apr 2026 | |
| Absynth Biologics | , | Website Gone Jan 2019 |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| CEL-SCI | Vienna, VA | Biologics |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| , | Website down Oct 2025 - Feb 2026 | |
| CanCure | , | No news 2017 - 2024 |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| ImmuVen | , | Website gone, Dec 2015 |
| Prognosys Bioscience | , | 10 years in stealth mode |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Resprotect | , | No update since 2012 as of 2020 |
| Core Dynamics | , | Gone |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| Gennova Bio | Pune, India | mRNA vaccine |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| Kivu Bioscience | San Francisco, CA | ADCs |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| Delpor | Brisbane, CA | Drug Delivery System |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Merck KGaA | Singapore, Singapore | |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| NeuroWave Systems | Beachwood, OH | EEG |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| , | Shut down Jan 2025 | |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Axonia Medical | , | Gone 2015 |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Tri-Pac | South Bend, IN | Contract Filling |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| CSSi | , | |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Amphora Medical | , | Shut down May 2019 |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Best Vascular Novoste | , | Now Novoste |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| Pangaea Pharmaceuticals | , | Became Zycos |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Facet Biotech | , | Bought by Abbott 2010 |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| SuraMedical | , | Most employees left, not registered in MN |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| , | No news 2015 - Jan 2026 | |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| CanBas | Shizuoka, Japan | Small Molecules |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| numares | Regensburg, Germany | Clinical Diagnostics |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Boca Pharmacal | , | Bought by Qualitest |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Tactic Pharma | , | Website gone, Apr 2018 |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| , | Renamed Numerion Labs, Oct 2025 | |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Large Scale Biology | , | Shut Down |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Louisville Bioscience | , | Now LBIdx |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| , | ||
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Elm Tree Medical | , | Shut down Nov 2020 |
| , | Website down Aug 2025 - Jan 2026 | |
| Axplora | Chennai, India | API manufacturing |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| IQVIA | Lenexa, KS | Clinical Research |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| Ortho Development | Draper, UT | Ortho Implants |
| Haini Pharmaceutical | Shanghai, China | Generics |
| Medarex | , | Bought by BMS 2009 |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Hansa Medical | , | Renamed Hansa Biopharma |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Lorantis | , | Merged with Celldex 2005 |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| YishengBio | , | Now YS Biopharma |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| ImmBio | , | Shut down Nov 2019 |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| , | Acquired by IQVIA | |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| , | Acquired by BICO, Aug 2021, $15M | |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| Nido Surgical | , | Shut down Apr 2022 |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Nanosonics | Sydney, Australia | Ultrasound |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| Omixon | Boston, MA | Next-gen sequencing products |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| IR2Dx | , | Gone, 2019 |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| Quanta Biosciences | , | Renamed QuantaBio |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| LinkChem | Shanghai, China | CDMO |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| PredxBio | Pittsburgh, PA | Image Analysis |
| LKC Technologies | Gaithersburg, MD | Electrophysiology Systems |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Sorbent Therapeutics | , | Gone post 2014 |
| Envision Genomics | , | Website gone Nov 2019 |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Cytiva | Amersham, UK | Medical Devices |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| MeiRui Pharma | , | Bought by GSK |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| , | Website down Jul 2025 - Nov 2025 | |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| , | Website down Jul 2025 - Dec 2025 | |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| HEC | , | Website down Dec 2024 - May 2025 |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Nereus | , | Website Gone late 2013, no info |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| MaxThera | , | Shut Down Dec 2011 |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Qardio | Covina, CA | Portable Heart Monitors |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| , | Website down Jul 2025 - Jan 2026 | |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| , | No news Jan 2021 - Jan 2026 | |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| Intact Genomics | St. Louis, MO | PCR kits |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| AQEMIA | Paris, France | AI Drug Discovery |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| NeoVentures | London, ON | Custom Aptamers |
| , | Website down Nov 2025 - Apr 2026 | |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| , | Website down Oct 2025 - Feb 2026 | |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| AAVLife | , | Renamed Annapurna |
| , | Website down Nov 2025 - Dec 2025 | |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| NIOX | Morrisville, NC | Asthma management device |
| Curia | Hyderabad, India | Contract Research |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| , | No news Mar 2021 - Jan 2026 | |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| , | Shut down Mar 2026 | |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| Advanced Peptides | , | No business filings since 2011 |
| Proteom | , | Acquired by Amura Ltd |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Statera Therapeutics | , | Shut down Jan 2022 |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Sequella | , | Ancient website ©2017, last news 2017 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Ottobock | Vienna, Austria | Prosthetics |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| 76Bio | , | Shut down Jan 2025 |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Ribon Therapeutics | , | Shut down May 2024 |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| Verséa Health | Tampa, FL | Diagnostics |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Platelet BioGenesis | , | renamed PlateletBio |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| Soluble Systems | , | Renamed Solsys Medical |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| Noble | Orlando, FL | Auto-injector Trainers |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Abselion | Cambridge, UK | Biologics Quantification |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| , | Website down Jan 2026 - May 2026 | |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| Michrom | , | Bought by Bruker, Feb 2011 |
| , | Website down Nov 2025 - Apr 2026 | |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| CeQur | Luzern, Switzerland | Insulin pump |
| Cell Therapy Ltd | , | Renamed Celixir |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| Cromos Pharma | Portland, OR | Clinical Research |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Torrington, CT | Animal Research Equipment | |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| 10BioSystems | , | Website Gone, Apr 2016 |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Bridge Laboratories | , | Gone 2013 |
 |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| Synergx | , | Owned by Morphogenesis |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| Genexa | , | Shut down before Nov 2023 |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Siga | Corvallis, OR | Small Molecules |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Alchemia | , | Gone, late 2017 |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| , | No news 2019 - Sep 2025 | |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| Oxis International | , | Renamed GT Biopharma |
| StemCell2MAX | , | Website gone Apr 2019 |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| Singular Genomics | San Diego, CA | Genomics |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| |
Lee, MA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| Venclose | , | Acquired by BD, Dec 2021 |
| Affinity Bio | , | Renamed MyriO Tx |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Astrum | Paris, France | Clinical Development CRO |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Imeka | Sherbrooke, QC | Neuroimaging |
| Aitia | Cambridge, MA | Analytics |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Hydra Biosciences | , | Website gone Mar 2019 |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| BenuBiopharma | , | Shut down Sep 2023 |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| CTC | Uppsala, Sweden | Clinical Site Network |
| CytoLogix | , | Gone, Sep 2012 |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| Apieron | , | Shut down, May 2010 |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| , | Shut down Oct 2025 | |
| , | Acquired by Sensei Biotherapeutics, Feb 2026 | |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| 89bio | Rehovot, Israel | Liver Treatments |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| , | Acquired by Lantheus, Jan 2025 | |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Lavipharm | Peania Attica, Greece | Small molecules |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Amplyus | , | Renamed miniPCR |
| Angelica Therapeutics | , | Gone 2018 |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| , | Shut down Aug 2025 | |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| Angel Biotechnology | , | Bankrupt, 2013 |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| UniteLabs | , | Shut Down |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| MicroPort | Clamart, France | Medical Devices |
| Avail Medsystems | , | Tech sold Mar 2024 |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| icometrix | Leuven, Belgium | Imaging AI |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Palo Alto, CA | Molecular Discovery Platform | |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| Teva | Toronto, ON | Small Molecules |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| NuAire | Plymouth, MN | Lab Equipment |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Memento Medicines | , | |
| Kastle Therapeutics | , | Closed May 2018 |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| , | Website down Oct 2025 - Feb 2026 | |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| GeoVax | Smyrna, GA | Vaccines |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| , | No news 2017 - Apr 2026 | |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| Targanta | , | Bought by The Medicines Company |
| Sepracor | , | Now Sunovion |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| AntiOp | , | Tech sold Jun 2015 |
| , | Acquired by Aptean, Oct 2016 | |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| Abazyme | , | Dissolved Jun 2017 |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| Quentis Therapeutics | , | Shut down late 2020 |
| CureGene | Shanghai, China | |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Cambrian Genomics | , | Shut down Dec 2017 |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Hybrigenics Services | , | Renamed ATON Group |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| Northway Biotech | Waltham, MA | Contract research |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Parexel | Newton, MA | Clinical Research |
| Cytiva | Marlborough, MA | Medical Devices |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Acretia | , | Gone |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| MeDiNova Research | , | Now part of Accelacare |
| AddBIO | , | Gone Oct 2023 |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| , | Website down Jan 2026 - May 2026 | |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| Neuroptix | , | Renamed Cognoptix |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| , | Shut down Nov 2025 | |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| ProPharma Group | Bozeman, MT | Consulting |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Vasade Biosciences | , | Gone |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| rhealth | Bedford, MA | Diagnostics |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Yunovia | Hwaseong, Korea | Small Molecules |
| , | ||
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| American Drug Co. | , | Renamed Five Star Products |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Pharmexa | , | Merged into Affitech, May 2009 |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Ansata Therapeutics | , | Out of business 2007 |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Flownamics | Madison, WI | Automated Sampling |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| Beta Pharma | Princeton, NJ | Small Molecules |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| CanSino Biologics | Tianjin, China | Vaccines |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| bioMerieux | Lombard, IL | Diagnostics |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| Keenova | Dublin, Ireland | Small Molecules |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Embody | Norfolk, VA | Soft Tissue Healing |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| SanBio BV | Uden, Netherlands | Antibodies |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Biotix | San Diego, CA | Lab Consumables |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| SK Biotek | , | part of SK pharmteco |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Pharmascience | Montréal, QC | Generics |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| Formulatrix | Bedford, MA | Lab Automation |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Chrysalis | Burlington, MA | GMP Space |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| Parion Sciences | Durham, NC | Mucosal Targets |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| , | Shut down Oct 2024 | |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| Hovione | Macau, China | Contract Manufacturing |
| ViaCord | , | Part of PerkinElmer |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Codon Devices | , | Closed Apr 2009 |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Celixir | , | Shell acquired Dec 2023 |
| , | Renamed Cyaris, Apr 2026 | |
| Geneffects | , | Shut down Feb 2020 |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| GenSure | Shijiazhuang, China | Diagnostics |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| , | Acquired by Altivera Medical, Mar 2026 | |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Texcell | Frederick, MD | Contract Research |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| Ikotech | , | Closed Dec 2015 |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Recodagen | , | Gone Jun 2009 |
| Horiba Instruments | Irvine, CA | Equipment |
| Axcella Health | , | Renamed Axcella Therapeutics |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Piramal | Ahmedabad, India | CDMO |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| Persomics | , | Gone 2019 |
| MacuClear | , | Website gone Jan 2019 |
| Roche | Buonas, Switzerland | Diagnostics |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| DiaVax Biosciences | , | Renamed Helocyte |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Biotheneum | , | Gone |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| ABD Bioquest | , | Renamed AAT Bioquest |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Metamark Genetics | , | Shut down 2018 |
| O-Ray pharma | , | Inactive Jun 2022 |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Medtronic | Minneapolis, MN | Medical Devices |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| Uncover Therapeutics | , | |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| , | Website down Jul 2025 - Dec 2025 | |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| Norganoid | Macclesfield, UK | Organoid Technology |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Celest Therapeutics | , | |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| , | Renamed Solario Bio | |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Ribomic | Tokyo , Japan | Aptamers |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| Rafagen | , | Website redirecting to Rophibio |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| CBH ClinTrials | , | now CenExelCBH |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| , | Gone Sep 2025 | |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| Gentian USA | Moss, Norway | IVD Products |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| Groove Biopharma | , | Gone 2015 |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Curia | León, Spain | Contract Development, Manufacturing |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| PPD | Middleton, WI | Contract R & D, Consulting |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Actylis | Port Washington, NY | Raw Materials |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| AIBioTech | , | Assets auction, Aug 2017 |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| XW Laboratories | , | Renamed XWPharma |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| GeneCopoeia | Rockville, MD | Lab reagents |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| , | Main person has four other jobs, Dec 2025 | |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| , | Website down Dec 2025 - Feb 2026 | |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| NewVac | , | |
| Amplified Proteomics | , | Shut down Jan 2006 |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Ergomed | Geneva, Switzerland | Clinical Research |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| Niramai | London, UK | AI-breast cancer detection device |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| Axial Biotech | , | Closed Mar 2013 |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| , | Website down Dec 2025 - Apr 2026 | |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| AlphaMab Oncology | Suzhou, China | Biologics |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| , | No news 2020 - Dec 2025 | |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| White Biotech Solutions | , | Shut Down 2019 |
| T&T Scientific | , | Website gone May 2023 |
| Hunterian Medicine | Cambridge, MA | CRISPR-based drug discovery |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| Innovagen | Lund, Sweden | Custom antibody development |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| OrthoData | , | Renamed Intellirod Spine |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Appia Bio | , | Shut down Aug 2025 |
| Alliance Spine | San Antonio, TX | Spinal implants |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| Galileo Research | , | No news since 2012, presumed gone |
| DxNow | , | Renamed ZyMot fertility |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Nura Bio | South SF, CA | Small Molecule |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| , | Merged with Nova Biomedical | |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| BioSyntech | , | Bought by Piramal |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| IDRx | , | Acquired by GSK, Feb 2025 |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| GenEndeavor | Hayward, CA | Diagnostics |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| Trek Therapeutics | , | Shut down Sep 2019 |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Savage Medical | , | Renamed Averto Medical |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Protein Forest | , | Bought by Cell Biosciences |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Primera Biosystems | , | Now PrimeraDx |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| CNS Research | , | Seem gone, 2020 |
| Neotech | , | Website down Jan 2019 |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Quantificare | Maringa, Brazil | Medical Imaging |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| XStalBio | , | Folded |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| TriVirix | , | Now Nortech Life Sciences |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Curia | Glasgow, UK | Contract Research, Development, Manufacturing |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| Proveri | , | Gone 2016 |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Viva Biotech | Shanghai , China | Contract Research |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Supratek Pharma | , | Website gone Sep 2017 |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| , | Website down Jan 2026 - May 2026 | |
| Neugenesis | , | Bought by Intrexon, 2011 |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Cell>Point | , | Cant find any confirmation they are active |
 |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| Deinove | , | Bankrupt Mar 2023 |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| MabSpace Biosciences | , | Renamed Transcenta |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Ionian Technologies | , | Gone Mar 2016 |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| ProteoVec | , | Website gone Jul 2015 |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| Global BioDevelopment | , | Website gone |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| Davol | , | Acquired by Bard, 1980 |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Sojournix | , | Shut down Jun 2021 |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| MicroPort | Saluggia, Italy | Medical Devices |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| GenturaDx | , | Bought by Luminex 2012 |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| Celemics | , | Gone Jul 2018 |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| DDi | London, UK | Clinical Software |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Lumen Bioscience | Seattle, WA | Biologics |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| NuVascular Technologies | , | Shut down Nov 2021 |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| Resilience | Hamilton, OH | Biomanufacturing |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Nigra | , | Acquired by Vernalis |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Enodar BioLogic | , | Gone, Jun 2014 |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Cyto360 | , | Website gone Aug 2018 |
| Körber | Hamburg, Germany | Production Monitoring Software |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| OSI Pharmaceuticals | , | Bought by Astellas |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| , | Website down Oct 2025 - Feb 2026 | |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Getinge | Mahwah, NJ | Medical Technology |
| Henderson Morley | , | Bankrupt |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| , | No news 2021 - Jan 2026 | |
| AtheroGenics | , | Assets Sold Off 2009 |
| , | Website down Jul 2025 - Oct 2025 | |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| Vernacare | Maple, ON | Surgical Devices |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| Oxehealth | , | Pivoted to mental health platform |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| MetaMorphix | , | Changed to Scidera Genomics |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Cebix | , | Shut down, Feb 2015 |
| Faze Medicines | , | Shutting down Nov 2022 |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Neurogene | Houston, TX | Genetic Therapies |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| Piramal | Turbhe, India | CDMO |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| Anaheim Clinical Trials | , | Now CenExelACT |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| AmCell Biosciences | , | Website gone Apr 2021 |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| BIOMODEX | , | Acquired by Mentice |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| ImmuNext | , | Website gone Feb 2025 |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| Bionovica | , | Website gone Dec 2022 |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Kona Medical | , | Closed, Dec 2016 |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| Scientia Advisors | , | Website gone Jul 2015 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| Upstate Biotechnology | , | Closed 2005 |
| Mednoxa | , | Website gone Jan 2020 |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| Vadovations | , | No info. 2012 SBIR grant |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Avadel Pharmaceuticals | Dublin, Ireland | 505(b)(2) product |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| Stryker | Flower Mound, TX | Medical Devices |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| , | Website down Dec 2025 - Apr 2026 | |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| BioTheryX | San Diego, CA | Small Molecules |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| NextImmune | , | Renamed NXI Therapeutics |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| Pevion Biotech | , | Gone, 2-19-14 |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| , | Website down Jan 2026 - May 2026 | |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Xhale | , | Acquired by Philips, Aug 2018 |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| , | No news 2021 - Sep 2025 | |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| CovX Research | , | Bought by Pfizer |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| Ventris Medical | Newport Beach, CA | Tissues |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| E3X Bio | , | Shut Down Mar 2019 |
| Accellacare | Raleigh, NC | Clinical Research |
| Accord Healthcare | Ahmedabad , India | Generics |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Trine Pharmaceuticals | , | Closed 2008 |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| Hemanext | Lexington, MA | Transfusion Technologies |
| MiNA Therapeutics | London, UK | Small activating RNA |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Dendritix | , | Renamed Argos Therapeutics |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| Adynxx | , | Website taken over Sep 2020 |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| SeromYx Systems | Woburn, MA | Systems Serology |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| AFID Therapeutics | , | Gone 2012 |
| , | Renamed Ribonexus, Nov 2021 | |
| Agile EndoSurgery | , | Gone |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Weatherden | London, UK | Clinical Consulting |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| Ergomed | Surrey, UK | Clinical Research |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| MiRus | Marietta, GA | Spine Implants |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| Interdict | San Francisco, CA | Small Molecules |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| Novosis | , | Acquired by Acino, 2006 |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Ergomed | Madrid, Spain | Clinical Research |
| BioSpherex | , | Renamed Metabiomics |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Audubon Bioscience | Houston, TX | Biospecimens |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| PegaOne | , | Centessa Company |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Purinomia Biotech | , | |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| GL Technologies | San Diego, CA | Calibration Services |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| RheoSense | San Ramon, CA | Viscometers |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| Baxter | Grosotto, Italy | Medication Delivery |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Light Sciences Oncology | , | Shut down late 2020 |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| GEROPHARM | Moscow , Russia | Large drug maker |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| PNP Therapeutics | Birmingham, AL | Outlicensed sole product Sep 2021 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| , | Website down May 2025 - Dec 2025 | |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| CombinatoRx | , | Now Zalicus |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Regentys | , | Acquired by Generex, Jan 2019 |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| , | Renamed Cordica Medical, Jan 2026 | |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Catalent | Winchester, KY | Contract Manufacturing |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Nanobiotix | Paris, France | Nanoparticles |
| Selten Pharma | , | Gone 2017 |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Viwit | Shanghai, China | APIs, Formulation |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| IQVIA | Parsippany, NJ | Clinical Research |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| Rubix Device | , | Website gone, Aug 2017 |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| , | Website down, COO gone Oct 2025 | |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| , | Filings late Jun 2025 | |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Mattson Jack | , | Now Kantar Health 2009 |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Apaxis Medical | , | Gone 2019 |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Proteome Sciences | Surrey, UK | Proteomics |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Regulaxis | , | No news 2020-2024 |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| Smart Biosciences | , | Renamed sb-Peptide |
| MeiraGTx | London, UK | Gene Therapy |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| Trident Lifeline | Surat, India | Generics |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| Cytiva | Freiburg, Germany | Medical Devices |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| SL Pharma Labs | , | Website gone May 2018 |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| Delpharm | Huningue, France | Contract Manufacturing |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| MSD | Ballydine, Ireland | Small Molecules |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Niche Generics | Arlesey, UK | Contract Generics |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| OD-OS | Irvine, CA | Retinal Laser |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Genometry | , | Shut down Dec 2019 |
| TME Pharma | Berlin, Germany | L-aptamers |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| Veramed | London, UK | Biostatistics and programming services |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Curia | Aurengabad, India | Contract Development, Manufacturing |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| Phenomix | , | Shut Down 2011 |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| ZyGEM | , | Renamed MicroGEM |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Sonavex | Baltimore, MD | Ultrasound |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| Hikma | London, UK | Medication Delivery |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| , | Website down Oct 2025 - Feb 2026 | |
| Pace | San German, PR | Analytical Testing, CDMO |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Mustang Bio | Worcester, MA | Immunotherapies |
| Createrna Science | Wuhan, China | Small Molecules |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
 |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| Tryton Medical | , | Shut down Jan 2021 |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| Sonus Pharma | , | Merged with Oncogenex |
| Pfizer | Hurley, UK | Consumer Healthcare |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| PROGEN | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| , | Seems to have shut down mid 2025 | |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| GemoPharm | , | No news 2017-2022 |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| Stada | Belgrade, Serbia | Generics |
| MedShape | , | Acquired by DJO, Apr 2021 |
| Capsigen | Vancouver, WA | AAV Vectors |
| Peptone | London, UK | Translational Biophysics |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| Proteotech | , | Website gone Jul 2015 |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| GeneAssess | , | Gone |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| Axplora | Shanghai, China | Purification Systems |
| Lupin | Goa, India | Generics |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| , | Acquired by Altaris, Mar 2025 | |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| SRI International | Menlo Park, CA | Independent Research |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Niche Generics | Hitchin, UK | Contract Generics |
| Cellevolve Bio | , | Shut down Aug 2023 |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| XtalPi | Cambridge, MA | AI Drug Design |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| Cellenion | Berlin, Germany | Single Cell Testing |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| Globe Life Sciences | London, UK | Strategy Consulting |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| Refeyn | Oxford , UK | Mass Photometry |
| Adaptix | Oxford, UK | Medical imaging |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| , | Website taken over, Jan 2026 | |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| , | Acquired by Tecan, Aug 2021 | |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| NetBio | , | Renamed ANDE |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| AxioMed | , | President left in 2018, not registered in MA |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Alerchek | , | Closed late 2016 |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| Pirche | Grünwald, Germany | Transplant Matching |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| Santen | Osaka, Japan | Ophthalmics |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Sterling | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| Monobind | Lake Forest, CA | IVD |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| Compliment Corporation | , | Closed Dec 2011 |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Solace Pharmaceuticals | , | Out of business 2011 |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| Admescope | Oulu, Finland | ADME-tox services |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Immunosyn | , | Charged with Securities Fraud |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| TTP Labtech | , | Renamed SPT Labtech |
| XaTek | , | No news 2021 - Feb 2025 |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| GenoMatix | , | Acquired by Intrexon |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| , | Website down Sep 2025 - Feb 2026 | |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| Esoterix | , | Bought by LabCorp, May 2005 |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Cadex Genomics | , | Shut down Jul 2024 |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| Clina Research | , | Website gone Jul 2023 |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| PL Developments | , | Parts of website taken over |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Veeva Systems | Radnor, PA | Life Science Software |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| iLeadBMS | Gyeonggi, Korea | Small Molecules |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Zai Lab | Shanghai, China | Small Molecules |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Intelliseq | Murrieta, CA | Genome Informatics |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| CytRx | , | Renamed LadRx Sep 2022 |
| Pharmaron | Cardiff, UK | R&D Services |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| , | Website down Oct 2025 - Jan 2026 | |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| , | Website down Apr 2026, seems bankrupt | |
| Ribonomics | , | Sold to MBL International |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| SegAna | , | Website down May 2021 - Sep 2021 |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Gene Sciences | , | Shut Down Jul 2019 |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| STARLIMS | Hollywood, FL | LIMS |
| Compucyte | , | Sold Assets to Thor Labs |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| , | ||
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Eos Biosciences | , | Shut down Oct 2020 |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| , | Renamed EarliPoint Health, Oct 2025 | |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| Gilead | Oceanside, CA | Small Molecules |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Cellenion | Tempe, AZ | Single Cell Testing |
| , | Website down Nov 2025 - Mar 2026 | |
| Grannus Biosciences | , | Gone |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| United Immunoassay | , | Business revoked Jan 2022 |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Cerimon | , | Gone |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| Nanobac Pharmaceuticals | , | Gone |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Crystal Bio Solutions | Cranbury, NJ | Bioanalytical services, biomarker discovery, CMC analytical services, and quantitative clinical pharmacology |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| , | Website down Nov 2025 - Apr 2026 | |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| ImmunArray | , | Shut Down, 2021 |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| Metrad Biosystems | , | Website gone |
| Predictive Biosciences | , | Closed 2013 |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Suvoda | Portland, OR | Clinical Trial Software |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Bioserve | , | Acquired by ReproCell, 2014 |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| BionX Medical | , | Acquired by Ottobock |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Gene Techno Science | , | Renamed Kidswell Bio |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Aspira Labs | , | Renamed Aspira Women's Health |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Alper Biotechnology | , | Gone |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| TamRx | , | Website taken over Aug 2020 |
| Boston Scientific | Galway, Ireland | Medical Devices |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| , | Website taken over, Nov 2025 | |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| , | Website down Jan 2026 - May 2026 | |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| , | Acquired by Maverix Medical, Dec 2023 | |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| , | Website down Oct 2025 - Feb 2026 | |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Brightflow Medical | Paris, France | Heart Failure Device |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| AzurRx | , | Merged into First Wave Bio |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| Infectex | , | Website taken over May 2020 |
| Hepta | San Francisco, CA | Liquid Biopsy |
| BinaryBio | , | Out of business Jul 2015 |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Revvity | Waltham, MA | Diagnostics, Services |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| Spirox | , | Bought by Stryker, Jul 2017 |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Immagene | , | Renamed Flindr Therapeutics |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Pathens | , | Website hijacked Sep 2020 |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Medicure | Winnipeg, MB | Small Molecule |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| AlphaGenix | , | Gone 2014 |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| CultureTrax | , | Shut Down Dec 2019 |
| Orchestra BioMed | New Hope, PA | Medical devices |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Personalis | Fremont, CA | Genome Services |
| MyoSyntax | , | Gone 2021 |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| Genomas | , | Website gone May 2020 |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| NsGene | , | Website gone |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| Viva Biotech | Jiaxing , China | Contract Research |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| PharmatrophiX | , | No news 2015 - Sep 2025 |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Lupin | Coral Springs, FL | Generics |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| ThauMDx | , | Closed down 2003, out of cash |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Catalyst Clinical Research | Schiphol, Netherlands | Clinical research solutions to the global biopharmaceutical industry |
| Artimplant | , | Bankrupt, 2013 |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| , | Renamed Torpedo Therapeutics | |
| Smithers | Akron, OH | Contract Research |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| Valneva | Livingston, UK | Biologics Manufacturing |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
 |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Greenstone Biosciences | Palo Alto, CA | |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| , | No news 2019 - Jan 2026 | |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| South Coast Clinical Trials | , | |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| , | Website down Nov 2025 - Apr 2026 | |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Cetero Research | , | Renamed PRACS Institute |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| Cue Health | , | Shut down May 2024 |
| Newgen Biopharma | , | Suspended trading due to scandal |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Devsynthesis | Austin, TX | Chemistry CRO |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| Visitube | , | No website Mar 2020 |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Madison Vaccines | , | Website gone Dec 2019 |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Boston Scientific | Cork, Ireland | Medical Devices |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Texcell | Shanghai, China | Contract Research |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| HarkerBIO | , | Shut down Apr 2019 |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Vanguard Therapeutics | , | |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| Novonesis | Paraná, Brazil | Enzymes |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Chaperone Therapeutics | , | Gone 2019 |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| Zai Lab | Hong Kong, China | Small Molecules |
| Starkey | Eden Prairie, MN | Hearing Aids |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| Altasciences | Overland Park, KS | Contract Research |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| Delpharm | L'aigle, France | Contract Manufacturing |
| WiseGene | , | Website gone jan 2020 |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| Minimus Spine | , | Only real employee now full-time at another company |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Point Biomedical | , | Liquidated Jul 2008 |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| OrphoMed | , | Shut Down 2022 |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Merix Bioscience | , | Renamed Dendrix |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| , | Website down Sep 2025 - Feb 2026 | |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| Spriaso | , | No news 2019 - May 2025 |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| Minntech | , | Now Medivators |
| Acrux | West Melbourne, Australia | Drug Delivery |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| Verix Health | , | Renamed Serpex Medical |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Gene Signal | , | Bankrupt, Apr 2021 |
| Rinat | , | Bought by Pfizer 2006 |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| Trophea Development | , | Liquidated Dec 2019 |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Curium | , | Dissolved, Mar 2015 |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| Journey Colab | , | Shut down Jan 2025 |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| , | Pivoted to defense, Feb 2026 | |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| , | Renamed Aurevia | |
| Coating Place | Verona, WI | Drug Delivery Services |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Vivamer | , | Shut down, Jul 2015 |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Abviva | , | Gone, 2008 |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Amresco | , | Acquired by VWR, Feb 2011 |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| EpicGenetics | , | Seems gone Jan 2024 |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Soin Neuroscience | , | Seems like one guy |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| EndoInSight | , | Website taken over Sep 2021 |
| Lusis | Hayward, CA | Diagnostics |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| , | Website down Jan 2026 - May 2026 | |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| , | Shut down 2025 | |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| Pierce | , | Part of Thermo Fisher |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Sanofi | Reading, UK | Small Molecules |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| Sierra Surgical | , | Shut down Feb 2019 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| PhytoMedical | , | Apparently Gone |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| iKaryos Diagnostics | , | Gone |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| Idience | San Francisco, CA | Cancer Therapies |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Folia Biotech | , | Website Gone May 2018 |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| JAJ International | , | Website not working, redirecting strangely |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| HawkCell | Lyon, France | MRI Research Technology |
| Bangalore, India | Contract Chemistry Services | |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| LipimetiX Development | , | Website gone, Jan 2020 |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Arraystar | Rockville, MD | Microarrays |
| DDi | Princeton, NJ | Clinical Software |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Clarivate | London, UK | Vascularized organoids |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| Cell Genesys | , | Merged with BioSante |
| MatTek | Ashland, MA | Cell Products, Services |
| Obenomics | , | No website Apr 2014 |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Rhaeos | Evanston, IL | Shunt Monitor |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| Libra Clinical Research Associates | , | Gone |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| Gen Plus | Munich, Germany | Formulation |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| ViroMed | , | Renamed Helixmith |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
 |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Intrexon | , | Renamed Precigen |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| Hua Medicine | Shanghai, China | Small Molecules |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| Daktari Diagnostics | , | Gone 2017 |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Apoptos | , | Acquired by Receptos |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| Solvay | , | Bought by Abbott 2010 |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Appili Therapeutics | Halifax, NS | Small molecule |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Remedium Bio | Needham, MA | Gene Therapy |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Hologic | Beijing, China | Diagnostic, Imaging |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| AlloCure | , | Website Gone, Jul 2015 |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| Ximedica | Plymouth, MN | Medical Device Services |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| Klogene Therapeutics | , | Gone 2019? |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| , | Website down Jun 2025 - Dec 2025 | |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Cytoplex Biosciences | , | Gone |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| , | Website down Sep 2025 - Dec 2025 | |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| Target Medicals | , | No news 2016 - Oct 2024 |
| Benchling | San Francisco, CA | Biotech Software |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| AxoTect | , | Phantom company |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| SmartCells | , | Bought by Merck Dec 2010 |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| , | No news 2018 - May 2026 | |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| American Biooptics | , | Renamed Avivo BioOptics |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| Serica Technologies | , | Bought by Allergan |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| , | Website down Jun 2025 - Dec 2025 | |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| Artera | Los Altos, CA | AI Diagnostics |
| ExThera Medical | Martinez, CA | Blood filtration |
| Rytvel Biotechnology | , | |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Gensignia | , | Website Gone, Aug 2017 |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| ProPharma Group | San Diego, CA | Consulting |
| Nizyme | , | Gone Jul 2015 |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| ApoImmune | , | Gone 2014 |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Stemnovate | Cambridge, UK | Research Cells |
| , | Website down Jul 2025 - Dec 2025 | |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Medtronic | Minneapolis, MN | Medical Devices |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| Biohit | Helsinki, Finland | Diagnostics |
| Nymirum | , | Renamed Base4, Feb 2023 |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| , | Acquired by StarFish Medical, Nov 2024 | |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| , | Acquired by Frontage, Jul 2021 | |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| , | Pivoted to food, Feb 2026 | |
| NormOxys | , | Gone |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| NeoDiagnostix | , | Website Down Feb 2025 |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Mardil Medical | , | Website gone Feb 2021 |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Nanosonics | Manchester, UK | Ultrasound |
| Qualiber | , | Presumed inactive, website gone |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Altasciences | Scott Township, PA | Contract Research |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| Karo Bio | , | Renamed Karo Pharma |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| , | ||
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| Panaxia | Lod, Israel | Medical Cannabis |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Integer | Plano, TX | Medical & Surgical Devices |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| QuantuMDx | Newcastle, UK | Diagnostics |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Jina Pharmaceuticals | , | |
| JCL Bioassay | , | Renamed CMIC |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| Genecare | , | Gone |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Root Lines Technology | , | Renamed Samabriva |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Noeledge | , | Shut down Jul 2024 |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Sampled | Motherwell, UK | Biostorage |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| Synergen | , | Bought by Amgen 1994 |
| ChemRegen | , | Seems gone Jan 2022 |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| , | Crypto Pivot, Nov 2025 | |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| FusionBio | , | Website down Sep 2025 |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| On-Q-Ity | , | Closed 2013 |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| Organogenesis | Canton, MA | Biologics |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Axikin Pharmaceuticals | , | Closed per Google |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Lupin | Mandideep, India | Generics |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Ergomed | Krakow, Poland | Clinical Research |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| Theragenics | Buford, GA | Medical Devices |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Pharsight | , | Merged with Tripos to become Certara |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Novaliq | Cambridge, MA | Drug Delivery |
| Relevant Bio | , | Shut Down Oct 2023 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Orthofix International | Lewisville, TX | Medical Devices |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Glide Pharma | , | Renamed Glide Technologies |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| MURO PHARM | , | Dissolved, May 2007 |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| Reach Separations | Nottingham, UK | Purification Services |
| SunMed | , | Renamed AirLife |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| Sanofi | Midrand, South Africa | Biologics |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| COOL-BIO | , | Gone |
| BioClinical Solutions | Chicago, IL | Clinical Trial Solutions |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| Ergomed | Kiev, Ukraine | Clinical Research |
| BioGaia | Stockholm, Sweden | Probiotics |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Alchemgen | , | Gone |
| Panacos | , | Believe they are inactive |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| Activ Surgical | Boston, MA | Surgical Software |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| DiagnoCure | , | Liquidated, Apr 2016 |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| Univfy | Los Altos, CA | IVF reports |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| SWITCH Biotech | , | Gone, 2020 |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| , | No news 2021 - Jan 2026 | |
| Pharmadax | New Taipei City, Taiwan | Generics |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| In Veritas Medical Diagnostics | , | Shell company |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Excalipoint Therapeutics | Shanghai, | |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Station X | , | Website Gone Mar 2018 |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| , | Renamed Entirety Biomedical | |
| Adrenergics | , | Gone Sep 2017 |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| , | Acquired by Instem, Jul 2025 | |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| , | Website down Jan 2026 - May 2026 | |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| , | Website down May 2025 - Sep 2025 | |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| , | Website down Oct 2025 - Feb 2026 | |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| , | Acquired by EPI, Mar 2022 | |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Carrington Labs | , | Changed Name to DelSite |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| DelSite | , | Bankrupt |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| , | Website down Oct 2025 - Feb 2026 | |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Menarini | Florence, Italy | Biologics |
| Norgine | Madrid, Spain | Specialty Pharma |
| Mesoblast | New York , NY | Regenerative Medicine |
| Blansett Pharmacal | , | Gone Jan 2019 |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| XenaCare | , | Gone |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| Gentel Bio | , | Ceased Operations 2012 |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| , | Website down Dec 2025 | |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| , | Website down Oct 2025 - Feb 2026 | |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Altasciences | Everett, WA | Contract Research |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| Genovis | Cambridge, MA | Nanoparticles |
| Sirana Pharma | , | Merged with Apexis Bio |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Amarin | Dublin, Ireland | Small Molecules |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| CoreBiome | , | Merged into Diversigen |
| Gentell | Yardley, PA | Wound Care |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Targeson | , | Website gone, Mar 2017 |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| Pinnaxis | Noida, India | Pharmacovigilance |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| Mithridion | , | Website Gone, Company appears to be as well |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| BioTeam | Middleton, MA | Scientific IT consulting |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| , | Subsumed into Synoptics | |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| Aytu BioScience | , | now Aytu BioPharma |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| Genentech | South SF, CA | Small Molecules, Biologics |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| PredictImmune | , | Shut down Nov 2023 |
| Anacura | Evergem, Belgium | Analytical |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| Sierra Neuropharmaceuticals | , | Not active |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| , | Renamed WallabyPhenox | |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Actera Pharmaceuticals | , | Closed |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| PreDxion Bio | , | Renamed Refractal |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Virometix | Schlieren, Switzerland | Vaccines |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| Proxygen | Vienna, Austria | Cancer Therapies |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Atugen | , | Acquired by SR Pharma 2005 |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| Createrna Science | Shanghai, China | Small Molecules |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Texcell | Evry, France | Contract Research |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| VytronUS | , | Shut down Mar 2020 |
| numares | Houston, TX | Clinical Diagnostics |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Peritia | Morrisville, NC | Consulting |
| Howfond | , | Website gone, Jul 2015 |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| Olymvax | Chengdu, China | Vaccines |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| GeneEx | , | Now RevDia |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| MYcroarray | , | Renamed Arbor Biosciences |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| PhoreMost | Cambridge, UK | Biologics |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| , | Winding down, Dec 2025 | |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| CMD Medtech | Columbus, OH | Medical Device Development |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| Eversana | Chicago, IL | Commercialization Consulting |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Takara Bio USA | San Jose, CA | Lab products |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| TransCellular Therapeutics | , | Gone 2019 |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Corin | Cirencester , UK | Orthopedics |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| EmerVax | , | Renamed Circurna |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| iWel | Exton, PA | Glucose Meters |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Calyx Pharma | Mumbai, India | APIs |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Arete Therapeutics | , | Out of Business |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| , | Acquired by Scantox, Sep 2024 | |
| , | Subsumed into Synoptics | |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| Helus Pharma | Toronto, ON | Psychedelics |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Allergenics Inc | , | Closed Mar 2007 |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Stat One | Morrisvile, NC | eClinical |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| Delpharm | Reims, France | Contract Manufacturing |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| CanTx | , | Website gone, Feb 2015 |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Daré Bioscience | San Diego, CA | Women's Health |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Flow Eighteen38 | , | |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| MerciaPharma | , | No updates 2014-2023 |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| GenomeKey | Bristol, UK | IVD Device |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| DiObex | , | Shut Down 2009 |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Neuro3 Therapeutics | Cambridge, | Small Molecules, siRNA |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Luye Pharma | Shanghai, China | Small Molecules |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| Invibio | Cleveleys, UK | Implants |
| Glenveigh Medical | , | Website down Sep 2024 |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| Sunol Molecular | , | Assets sold 2005 |
| Apolife | , | Renamed Biosavita |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| Matritech | , | Assets bought by Matritech 2007 |
| PregLem | , | Acquired by Richter, Oct 2010 |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| , | Acquired by IQVIA | |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| , | Website down Aug 2025 - Jan 2026 | |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Roche | Tucson, AZ | Diagnostics |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| , | Pivoted to Crypto, Oct 2025 | |
| CRI Lifetree | , | Part of PRA Health Sciences |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| AGILeBiotics | , | Shut down 2024? |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Accellacare | Bristol, TN | Clinical Research |
| Nensius Research | , | Website Gone |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Accellacare | Rocky Mount, NC | Clinical Research |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| Amachumu Bio | , | Shut down April 2021 |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| , | Website taken over May 2026 | |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| , | Merged with DefiniGEN to become pixl.bio | |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| Altasciences | Cypress, CA | Contract Research |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Protox Therapeutics | , | Now Sophiris Bio |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| NemaPharm | , | Defunct? |
| Spinafx Medical | Toronto, ON | Steroid Injection Device |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Urogenix | , | Acquired by Astellas |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Medipacs | , | Shut down Jul 2024 |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| , | Renamed Athens Bioscience, Mar 2026 | |
| , | Website down Jan 2026 - May 2026 | |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| Boston Scientific | Spencer, IN | Medical Devices |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Sygene Technologies | , | Website gone Nov 2018 |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| accuFD | , | Closed Dec 2017 |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| TissueNetix | , | Gone Feb 2018 |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| , | Website down Jun 2025 - Dec 2025 | |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| , | Became part of Accelerator, Dec 2025 | |
| Rx3 | , | Now Trius Therapeutics |
| BGI | Shenzhen, China | Genetic Testing |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| Neoantigenics | , | Website gone Sep 2017 |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| Novotech | Taipei, Taiwan | Clinical Research |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| DDL | Edison, NJ | Device Testing |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| VG Life Sciences | , | Shell company |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Ipsen | Wrexham, UK | Biologics |
| Seneb Biosciences | , | Gone 2017 |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Novelty Nobility | Seongnam, Korea | ADCs |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Lung Bioengineering | , | Part of United Therapeutics |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| August Therapeutics | , | Shut down Dec 2024 |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| , | Shut down Jan 2025 | |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| SphynKx Therapeutics | , | Gone |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Spiden | , | Renamed Liom, Jul 2024 |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| EndoSphere | , | Gone pre-2011 |
| , | Renamed Valion Bio, Apr 2026 | |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Gene Labs | , | Bought by GSk 2008 |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| Ikano Therapeutics | , | Gone |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| Scintillant Bioscience | , | Gone May 2025 |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| , | Website down Nov 2025 - Apr 2026 | |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| Activated Cell Therapy | , | Changed name to Dendreon |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| Ergomed | Moscow, Russia | Clinical Research |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Martek Biosciences | , | Bought by DSM |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| Minimally Invasive Devices | , | Shut down |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| , | Acquired by Affluent Medical, Feb 2026 | |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Omniseq | , | Acquired by LabCorp, 2021 |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| RetiPharma | , | Dissolved Nov 2019 |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| , | Crypto Pivot, Oct 2025 | |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Scholar Rock | Cambridge, MA | Biologics |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| InfraReDx | Bedford , MA | Medical Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| Bioxene | , | Website gone, Company Presumed gone |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| GeneProt | , | Shut down Apr 2005 |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| , | ||
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| GenEscence | , | Gone Jul 2013 |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Gene ID inc | , | Website taken over |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| MicroStem | , | Gone Jun 2017 |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Covalent Bioscience | , | Shut down, 2025? |
| Apotex | Toronto, ON | Small Molecule Generics |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| MetaStat | , | Website gone May 2019; Shell Company |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| Curia | Frankfurt, Germany | Contract Development, Manufacturing |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Graybug | , | Now Graybug Vision |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| Covaris | Woburn, MA | DNA Sample Prep |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| Trillium Diagnostics | , | Closed Jul 2016 |
| VastBiome | , | Renamed PragmaBiome |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| FineHeart | Pessac, France | Heart Failure Device |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| TAI Diagnostics | , | Gone |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| NuLife Sciences | , | Shell acquired for a security business |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| Celunol | , | Merged with Diversa to become Verenium |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Trilations | New York, NY | Strategic Consulting |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| Indago | , | Renamed Lazurite |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Proimmune | Oxford, UK | Immunology research products |
| Sophiris Bio | , | Shut down May 2020 |
| TauTaTis | , | Shut down 2011 |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| SIRGA Advanced Biopharma | , | Appears defunct |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Recon Therapeutics | , | Shut down Jun 2017 |
| MEDISPECTRA | , | Gone 2002 |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| VLST Corp | , | Wound Down, Jun 2013 |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Otsuka | Rockville, MD | Small Molecules |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Celerion | Vienna, Austria | Clinical Research |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| Oticon | Smørum, Denmark | Hearing Aids |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Xenikos | , | Shut down early 2023 |
| hVIVO | London, UK | Viral Services |
| , | Website down Aug 2025 - Jan 2026 | |
| Gerard Biotech | , | Lab supplies, seems defunct |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| IQVIA | Durham, NC | Clinical Research |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| , | Website down Jul 2025 - Jan 2026 | |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| 4HF Biotec | Freiburg, Germany | Anti-cancer Treatments |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| , | Website down Dec 2025 - Apr 2026 | |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| Nasseo | , | Gone |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| AlphaVax | , | No employees on LI. Not sure active |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| Saffron Therapeutics | , | Website down Oct 2021 |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| Novacea | , | Bought by Transcept |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| Syncro Medical | Langhorne, PA | Software development |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Ottobock | Duderstadt, Germany | Prosthetics |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| Elixir Medical | Milpitas, CA | Stents |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| Mojave Therapeutics | , | Gone |
| Xenomics | , | Now TrovaGene |
| Meabco | , | |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Nuvation Bio | New York, NY | Oncology Treatments |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| , | Website down Jul 2025 - Dec 2025 | |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| BiVACOR | Houston, TX | Heart replacement |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| Bayer | Berlin, Germany | Small Molecules |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Belyntic | Berlin, Germany | Immunotherapies |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| , | Acquired by Bruker, May 2024, €870M | |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Proxima | New York, NY | AI Protein Folding Platform |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| LENSAR | Orlando, FL | Cataract Laser |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| Syndexa Pharm | , | Closed Jul 2013 |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| , | Assets moved to Co-Diagnostics, 2013 | |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| Hybrigenics | , | Renamed ATON |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| MicroCam | , | Shut down 2015? |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| Altheos | , | Closed |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| Selventa | , | Closed 2016 |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Crown Bioscience | San Diego, CA | Drug Development |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| Visgo Therapeutics | , | Gone Jun 2018 |
| Biolab Pharma | São Paulo, Brazil | Small Molecules |
| , | Renamed Ladder Bio, Nov 2025 | |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Genyro | San Francisco, CA | DNA Construction Technology |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| PharmedArtis | , | Gone 2019 |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Blackfynn | , | Gone Apr 2022 |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Alt Bioscience | , | Now PDx Biotech |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| Arginox Pharmaceuticals | , | Apparently Gone |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Gerostate Alpha | , | Shut down Dec 2024 |
| amcure | , | Liquidated Sep 2024 |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| OmniBiome Therapeutics | , | Gone 2014? |
| BioDot | Irvine, CA | Equipment |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| PolyTherics | , | Joined Antitope to become Abzena |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| IQVIA | Durham, NC | Clinical Research |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Biovertis | , | Acquired by Deinove, May 2018 |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| ReSync Bio | , | Acquired by Benchling 2025 |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| Protypia | , | |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| Quellthera | , | Subsumed into Liveleaf |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| Ileo Science | , | Seems gone Mar 2022 |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| Norac Pharma | Azusa, CA | API Manufacturing |
| CorTechs Labs | , | Renamed Cortechs.ai |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| , | Website down Nov 2025 - Apr 2026 | |
| Sixal | , | SBIR, Presumed defunct |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| 2 Bridge | Zoersel, Belgium | Consulting |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| AerovectRx | , | No news since 2006, Website gone |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| NanoTess | Calgary, AB | Biocatalysts |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| Affymax | , | Dissolved 2014 |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| DiAthegen | , | Website Gone Oct 2015 |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Cogenics | , | Now Beckman Coulter Genomics |
| Arcellx | Rockville, MD | Adaptive Immune Cell Therapies |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| , | Website taken over Feb 2026 | |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Neurogene | New York, NY | Genetic Therapies |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| , | DNA origami nanotechnology | |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| Xegen | Gemenos, France | NGS Data Analysis |
| Bard1 | , | Renamed INOVIQ |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| Bio-Processing Alliance | , | Website now for a training company |
| Generex Biotechnology | , | Website gone Feb 2024 |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| , | Website down Jul 2025 - Jan 2026 | |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| Surface Logix | , | Bought by Nano Terra |
| CohBar | , | Shut down, late 2023 |
| , | Website down Jan 2026 - May 2026 | |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| Imcyse | , | Liquidating, Jun 2025 |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| Analog Pharma | Princeton, NJ | Generics |
| Cato Research | , | Renamed CATO-SMS |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| LightMed | , | |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Johari Medtech | Jodhpur, India | Medical Devices |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Adepthera | , | Shut down 2014 |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Zai Lab | South SF, CA | Small Molecules |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Correlogic | , | Assets bought by Vermillion 2011 |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| Stemnovate | Cambridge, UK | Research Cells |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| NNS Clinical Research | , | Gone |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Acylin Therapeutics | , | Assets sold 2014 |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| Saniona | Glostrup, Denmark | Small Molecules |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| , | Website down Jun 2025 - Dec 2025 | |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| Genmab | Utrecht, Netherlands | Biologics |
| Accelrys | , | Bought by Dassault, 2014 |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Regenicin | , | Residential address, three employees, no money |
| , | No news Sep 2010 - Oct 2025 | |
| Stimwave | , | Bankrupt, Oct 2022 |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Centinel Spine | West Chester, PA | Spinal Implants |
| Biodel | , | Merged with Albireo, Oct 2016 |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| Carticept Medical | , | Dissolved Feb 2020 |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Avineuro | , | Website taken over Feb 2024 |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Locanabio | , | Shutting down late 2023 |
| , | Website down May 2025 - Dec 2025 | |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| Medion Diagnostics | , | Bought by Grifols? |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Leukosight | , | Gone, website is online pharmacy now |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| Incyte | Wilmington, DE | Small Molecules |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Telo Genomics | Toronto, ON | Diagnostics |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| , | Website down Jan 2026 - May 2026 | |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| Quintessence Biotech | , | Biomimetic Separation |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| Dante Labs | , | Seems to be Dante Genomics now |
| ARC Medical | , | Acquired by Typenex Medical |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| Novonesis | Bangalore, India | Enzymes |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Biotagenics | , | Renamed MedBiome |
| Aerogen | Galway, Ireland | Nebulizers |
| Azad Pharma | Hangzhou, China | APIs, generics |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| Strides Arcolab | , | Now just Strides |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| Clinical Microbiomics | , | Merged into cmbio |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| VersaPharm | , | |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Repligen | Waltham, MA | Protein Manufacturing |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| Pharos iBT | , | aka Pharos iBio |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Jaleva Pharmaceuticals | , | Gone |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| Courante Oncology | Excelsior, MN | Clinical Research |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Spine View | , | Gone |
| Sinobioway | , | |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| Novo Nordisk | Beijing, China | Inflammation Research |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Vyteris | , | Bankrupt 2012 |
| Cytel | Pune, India | Clinical software, statistical services |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Procognia | , | Website Gone, Layoffs 2014 |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| , | Renamed Proxoma, Jan 2026 | |
| WntResearch | , | Shell acquired by Opsy |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| , | Website down May 2025 - Sep 2025 | |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| Biomoles | , | Closed Sep 2017 |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| EpiFinder | , | Gone May 2025 |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Bioptimus | Paris, France | AI Drug Discovery |
| Almac | Craigavon, UK | Pharmaceutical Services |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| VitamFero | , | Website gone Aug 2018 |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| Anumana | Cambridge, MA | AI ECG reading |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| Alacrity Biosciences | , | Gone post-2011 |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| Metrohm | Houston, TX | Lab Data Management Software |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Octapharma | Vienna, Austria | Plasma Products |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Gen-probe | , | Acquired by Hologic 2012 |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| Effipharma | , | Marked as closed by Google |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Genyous Biomedical International | , | Presumed Gone |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| Fairway Medical Technologies | , | Website gone |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| TRIFARMA | Rozzano, Italy | APIs |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| EPD Biotherapeutics | , | |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| APCRA | , | Shut down 2020 |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| ActivX Biosciences | , | Shut down Mar 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| Huons | Seongnam, Korea | Small Molecules |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| , | Winding down Jan 2026 | |
| Mirador Biomedical | , | Shut Down 2019 |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Lyndra | Lexington, MA | Month-long Drug Delivery |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| GlycoEra | Boston, MA | Custom Glycan Platform |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Sciele Pharma | , | Bought by Shionogi |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Convergen LifeSciences | , | Renamed Genprex |
| ICU Medical | San Clemente, CA | Disposable medical products |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| Getinge | Tournefeuille, France | Medical Technology |
| Narus Development Solutions | , | Gone |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| Accellix | Jerusalem, Israel | On-demand Assays |
| Baccuico | , | Renamed Bactobio |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| , | Website down Jan 2026 - May 2026 | |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| CompanyLogo | City, State | Business |
| Amarin | Bridgewater, NJ | Small Molecules |
| Bayer | Bitterfeld, Germany | Small Molecules |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Agrisera | Vännäs, Sweden | Antibodies |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| ChemPacific | Baltimore, MD | Chemicals |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| Zars Pharma | , | Acquired by NuVo Research |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Cuda Pharmaceuticals | , | Presumed gone |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| Transdermal Technologies | , | Website Gone |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Hemanext | Avon, MA | Transfusion Technologies |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| myoscience | , | Renamed iovera |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| TNI Biotech | , | Renamed Immune Therapeutics |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| , | Website down Dec 2025 - Apr 2026 | |
| Theravance Biopharma | South SF, CA | Small Molecules |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Biotia | Brooklyn, NY | AI Genomics |
| WideCELLS | , | Shut down Nov 2019 |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Rallybio | New Haven, CT | Therapeutics |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Actome | Freiburg, Germany | Protein Quantification |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Evvy | New York, NY | At-home vaginal microbiome test |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| Senetek | , | Not sure what happened, no site, seem gone |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| Dey LP | , | Bought by Mylan 2007 |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Epic Sciences | , | Shut down May 2025 |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| |
Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| ISM Therapeutics | , | Website Gone, no response from employees |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| GliaGen | , | Renamed CaCy Therapeutics |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
 |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Clinilabs | Eatontown, NJ | Clinical Research |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Otonomy | , | Laid off all employees, Dec 2022 |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Getinge | Wayne, NJ | Medical Technology |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| Qurasense | , | Renamed Qvin |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| PhotoSonix Medical | , | Now a licensing outift |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| LabConnect | Johnson City, TN | Lab Services |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| , | Website down May 2025 - Jan 2026 | |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| CertiRx | , | Shut down |
| NextPharma | London, UK | Contract Research & Development |
| ApoVax | , | Shut down Jul 2014 |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Plexision | Pittsburgh, PA | Diagnostics |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| May Health | Paris, France | Ovulation Restoration Therapy |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Organix | Woburn, MA | Contract Research & Development |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| Xencor | San Diego, CA | Antibody Discovery |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| Neuron23 | South SF, CA | AI-drug discovery |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
 |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| Wacker | Munich, Germany | Polymers, Resins |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| Simbex | Lebanon, NH | Biomechanical devices |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| Aviria Biosciences | , | Disappeared |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| BBB Therapeutics | , | Bankrupt 2015 |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| NeuClone | Sydney, Australia | Biosimilars |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| ProUroCare Medical | , | Gone |
| Almirall | Barcelona, Spain | Small Molecules |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Asuragen | Austin, TX | Diagnostics |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| MedGyn Products | Westmont, IL | OBG Devices |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Doylestown, PA | RTSM Platform | |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| Green Cross | , | Renamed GC Pharma |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| Nvelop Therapeutics | , | |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| ResearchDx | Irvine, CA | Diagnostics |
| Silere Medical Technology | , | Shut down Dec 2013 |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| , | ||
| Akttyva Therapeutics | Mansfield, MA | AI-based Drug Discovery |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| Rhythmedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Amrita Therapeutics | , | Seems gone |
| , | Shut down Mar 2026 | |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| Scientific Industries | Bohemia, NY | Lab equipment |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Annova Chem | , | Gone, 2017 |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| Alliqua | Langhorne, PA | Hydrogels |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| MabCo | , | Renamed Agenix |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| Owkin | New York, NY | AI for Medical Research |
| SaluMedica | , | Website Gone Jul 2015 |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| Evonetix | Cambridge , UK | Desktop Platform for DNA Synthesis |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Axxam | Milan, Italy | Drug discovery services |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Lupin | Maharashtra, India | Generics |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Cancer Insight | , | Renamed LumaBridge |
| Prominex | San Diego, CA | POC Diagnostics |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| XellSmart | Suzhou, China | Cell Therapy |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Curio Bioscience | Palo Alto, CA | High Resolution Spatial Biology |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| , | Renamed MindWalk, Sep 2025 | |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| Antara Biosciences | , | Bankrupt 2007 |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| Akkadix | , | Gone 2001 |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| Pfizer | Kalamazoo, MI | Manufacturing |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| 121 Bio | , | Gone mid 2016 |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| HeartVista | , | Renamed Vista.ai |
| Tikcro Technologies | , | Liquidating 2021 |
| , | Website down Sep 2025 - Feb 2026 | |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Able Labs | , | big FDA trouble, gone |
| Pulse Biomedical | , | Distributor |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Hepalink | Shenzhen, China | Heparin API |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Amadix | Valladolid, Spain | Diagnostic development |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| , | Website down Jan 2026 - May 2026 | |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| 3D Biomatrix | , | Closed down |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Attralus | Naples, FL | Amyloidosis Treatments |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Verus Pharmaceuticals | , | Dissolved |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| Okairos | , | Acquired by GSK, May 2013 |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Virtici | Seattle, WA | Product / Company Incubator |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Delpharm | Evreux, France | Contract Manufacturing |
| NeuralInk | Fremont, CA | Neural Implants |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| BrainScope | Bethesda, MD | EEG characterization |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| genOway | Lyon, France | Rat and cell models |
| ObvioHealth | New York, NY | Clinical Study Software |
| JD Bioscience | Seoul, Korea | Small Molecules |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Orexia | , | Acquired by Centessa |
| Profound Medical | Mississauga, ON | Real-time MRI |
| , | Acquired by MannKind, Oct 2025, $296M | |
| DFE Pharma | Goch, Germany | Excipients |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Tribiosys | , | Appears defunct, likely late 2007 |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Quantamerix | , | No info since 2012, never registered in MA |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Abcam | Cambridge, UK | Antibodies |
| ADS Biotechnology | , | Bankrupt 2014 |
| Proteonomix | , | Shell Company |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| Gentegra | , | Part of IntegenX |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| PathAI | Boston, MA | AI Powered Pathology |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Stentys | , | Website down May 2021 - Oct 2021 |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| SVBio | , | Changed name to Lifecode |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| Cairn Research | Kent, UK | Scientific Instruments |
| Institute for Drug Discovery | , | Gone |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Intelliseq | Kraków, Poland | Genome Informatics |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| InteKrin | , | Owned by Coherus Biosciences |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Moleac | Singapore, Singapore | Stroke Products |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| GnuBIO | , | Bought by Bio-rad |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| , | Shut down Jul 2014 | |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| SineuGene | Beijing, China | Gene Therapy |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Delpharm | Lille, France | Contract Manufacturing |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| BGI | Hong Kong, China | Genetic Testing |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| XDx | , | Changed name to CareDx |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Molecular Sensing | , | Business revoked Aug 2019 |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| Akubio | , | Bankrupt Sep 2007 |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| Inventiva | Daix, France | Small Molecules |
| Sanofi | North York, ON | Biologics, Vaccines |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Piramal | Mahad, India | CDMO |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Genemod | Edmonds, WA | Lab management software |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Website down Sep 2025 - Dec 2025 | |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| Mabcare Therapeutics | , | |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Avivo BioOptics | , | Website down Dec 2022 |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| AtriCure | Mason, OH | Cardiovascular Devices |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Medicure | Princeton, NJ | Small Molecule |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Stada | Bad Vilbel, Germany | Generics |
| Procos | Cameri, Italy | Contract Manufacturing |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| BioDevek | , | Formerly LabCentral, seems gone |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| miR Scientific | , | Renamed miRNA Scientific |
| NewHeart Devices | , | Gone |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Clinnex | Ahmedabad, India | Clinical Research |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| Lux Biosciences | , | Gone |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| OvaGene Oncology | , | Gone Feb 2020 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Cellink | Kyoto, Japan | Bioprinting |
| Quantificare | Biot, France | Medical Imaging |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| , | Acquired by Bruker, Sep 2020 | |
| MilliporeSigma | Madison, WI | Small Molecules |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| OmniGuide | Billerica, MA | Surgical technology |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Viravaxx | , | |
| Inverness Medical | , | Renamed Alere 2011 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Cytonome | , | Shut down Nov 2009 |
| , | Acquired by Healx, Sep 2025 | |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| RNA Therapeutics | , | No website Mar 2020 |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Algenics | , | Website gone Dec 2015 |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Amp Orthopedics | , | Shut down, 2012 |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Proacta | , | Gone 2014 |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Stellartech Research | Milpitas, CA | Electronic device development |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| AMDL | , | Now Radient Pharmaceuticals |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| Cytheris | , | Out of business 2013 |
| MabQuest | , | No website Dec 2018 - May 2023 |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| PnuVax | , | No news 2017 - Aug 2024 |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Coeptis | , | |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Stiefel | , | Acquired by GSK |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| Lexogen | Vienna, Austria | RNA kits |
| Greppo Technologies | , | Renamed Verix Health |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| ImmuneWorks | , | Website gone, Apr 2018 |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Limerick Bio | , | Gone 2011 |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Curry Pharmaceuticals | , | Closed 2008 |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Anulex Technologies | , | Closed 2014 |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| Comac Medical | Sofia, Bulgaria | European CRO |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| LC Technologies | , | Renamed EyeGaze |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| , | Website down Feb 2025 - Dec 2025 | |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| ImmuneXcite | , | Closed Oct 2017 |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| Vericel | Cambridge, MA | Cellular Therapy |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Pharmion | , | Acquired by Celgene 2007 |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| , | Website down Jun 2025 - Dec 2025 | |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Curia | Hopkinton, MA | Contract Development, Manufacturing |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Recipharm | Strangnas, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| ArunA Biomedical | , | |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Lavipharm | East Windsor, NJ | Small molecules |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| Avance Clinical | Firle, Australia | Clinical Research |
| Purdue Pharma | Stamford, CT | Small Molecules |
| Genomic Solutions | , | Acquired by Digilab |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| Terapio | , | Website Gone, Sep 2020 |
| Advanz Pharma | London, UK | Specialty Generics |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| , | Website down Aug 2025 - Jan 2026 | |
| Silktap | , | Liquid silk. Site gone |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| , | Website down Dec 2025 - Apr 2026 | |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| |
Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Axbio | Santa Clara, CA | Biochips |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| bioTHER | , | Gone |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| OperaCRO | , | Now part of Tigermed |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Guangzhou, China | Clinical Research | |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| , | No news 2019 - Sep 2025 | |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| Lab901 | , | Bought by Agilent |
| Eternans | , | Shut down Jul 2022 |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| OriMAbs | , | Gone post 2022 |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Anergis | , | Liquidating, Jan 2021 |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| Sermes | Madrid, Spain | Full Service CRO |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Nexus BioPharma | , | No news 2017-2022 |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| Relion | , | Shut down 2015? |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Invectys | Paris, France | DNA Vaccine |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Website down Jul 2025 - Dec 2025 | |
| Syntagon | , | Acquired by Ardena, May 2018 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Kinaxo | , | Bought by Evotec |
| Berkshire, UK | Clinical Trial Solutions | |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ERT | , | Renamed Clario, Nov 2021 |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Hesperos | Orlando, FL | Human-on-a-chip |
| Celerion | Zurich, Switzerland | Clinical Research |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Keenova | Bridgewater, NJ | Small Molecules |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Vyriad | Rochester, MN | Immunovirotherapy |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| Curia | San Cristóbal, Spain | Contract Development, Manufacturing |
| , | Shut down Dec 2025 | |
| Parexel | Harrow, UK | Clinical Research |
| Optime Therapeutics | , | Acquired by Lippomix |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| Celtaxsys | , | No longer active, Aug 2020 |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| , | Website 404 Sep 2025 - Apr 2026 | |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Basecamp Research | London, UK | AI-Biology Data |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| , | Website down Oct 2025 - Jan 2026 | |
| Zydus Cadila | Ahmedabad, India | Generics |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Bionsight | Seoul, Korea | Database For Research |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| Clinisys | Tucson, AZ | LIMS Platform |
| Niche Generics | Dublin, Ireland | Contract Generics |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Vessel Biosciences | , | Shut down Mar 2023 |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| Innexus Biotechnology | , | Gone |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| , | Winding down Apr 2026 | |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| Sinotherapeutics | Shanghai, China | Generics |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Reserva | , | Renamed NeurMedix, 2016 |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| YMC Process Technologies | Devens, MA | Purification Technology |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| , | Website down Aug 2025 - Jan 2026 | |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| Profil | Neuss, Germany | Clinical Research Services |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| Cellipse | , | Website taken over May 2020 |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| ActivaTek | , | Acquired by North Coast Medical |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Protein Design Labs | , | Renamed PDL Biopharma |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| NeuroVia | , | Shut down 2019 |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Omnitura | , | Website gone Jan 2022 |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| Berg | , | Acquired, Jan 2023 |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Apicore | Gujarat, India | API Development & Manufacturing |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| , | No news 2016 - Sep 2025 | |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| KALA BIO | Arlington, MA | Drug Delivery |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| X7 Research | , | Website hijacked Feb 2025 |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Osteolab | , | Spam site |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| 149 Medical | , | Shut down Dec 2022 |
| Myrexis | , | Liquidating 2013 |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Rgene | , | Late business filings Aug 2021 |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| BioAMPS | , | Gone |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| , | No website updates since 2013 as of Dec 2025 | |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| MindWalk | Victoria, BC | Custom Antibodies |
| Ionpath | , | Shut down Feb 2025 |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| Cellex | , | Presumed Gone |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| , | Website down Jul 2025 - Jan 2026 | |
| Jubilant Cadista | Salisbury, MD | Fully Integrated Contract Research, Generics |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquired by Insphero, Nov 2025 | |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| ActoBio Therapeutics | , | Brought into Precigen |
| Putney | , | Acquired by Dechra, Mar 2016 |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Accellacare | Hickory, NC | Clinical Research |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| GIVAX | Boston, MA | GI Vaccines |
| Flux Biosciences | , | Shut down, ~2022 |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| , | Reportedly Closed Mar 2026 | |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Silence Therapeutics | Berlin, Germany | RNAi |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| Enci Therapeutics | , | No website, business suspended by NC |
| , | Website down Jun 2025 - Dec 2025 | |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Percivia | , | Shut Down 2012 |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Reading, UK | Analytical Services | |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Dorphan | , | Shut down so owner could spend more time skiing |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| , | No news 2018 - Sep 2025 | |
| Velia Therapeutics | , | Shut down Jan 2025 |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| Akrivis Technologies | , | Gone Jun 2021 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| , | Website messed up, single employee, Dec 2025 | |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| Covenant Therapeutics | , | Gone |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Elix | Tokyo, Japan | AI Drug Discovery |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| Kallyope | New York, NY | Gut-brain axis focus |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| NeoPharm | , | Merged with Insys Therapeutics |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| NEXGEL | Langhorne, PA | Hydrogels |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| InvivoGen | San Diego, CA | Life Science Reagents |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Nanogen | , | Now Epoch Biosciences |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Medtronic | Galway, Ireland | Medical Devices |
| AbbVie | Waco, TX | Contract Manufacturing |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| America Stem Cell | , | Changed name to Targazyme |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| AndroBioSys | , | Presumed gone |
 |
Fontenilles, France | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| Endocare | , | Website down Jan 2021 - May 2021 |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| EPISONA | , | Gone Nov 2018 |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| F2G | Cheshire, UK | Antifungals |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| , | Part of Genesis Biotechnology Group | |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| GMP-Orphan France | , | Renamed Orphalan |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| Therabest | Seoul, Korea | iPSC |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| seqWell | Beverly, MA | Sequencing Service |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| AbbVie | Dublin, Ireland | Medical Devices |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| GlycoSolutions | , | Closed Aug 2015 |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Novogene | Beijing, China | Genomic Services |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| SynAm Vaccine | , | Gone 2017 |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| CardiRen Biomedical | , | Gone Aug 2017 |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| KXT bio | , | Shut down 2019 |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| Multerra Bio | , | Bankrupt May 2021 |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation psuedo-subsidiary | |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| EMS | Hortolândia, Brazil | Small Molecules |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| PMG Research | , | Now Acellacare |
| , | Renamed Imviva Biotech, Oct 2025 | |
| CombImmune | , | Website Gone Jul 2015 |
| Therics | , | Acquired by Integra |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Ennov | Paris, France | Software Solutions |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| Wyeth | , | Bought by Pfizer |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Maxivax | , | Renamed Release Therapeutics |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| IDM Pharma | , | Acquired by Takeda |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| SiliCycle | Québec, QC | Separation Technologies |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Archimedes Vascular | Birmingham, | Hypertension Devices |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Apollo Scientific | Manchester, UK | Research Products |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| Autotelic | , | Gone 2022 |
| Virco | , | Bought by J&J |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| CisThera | , | Shut down Jan 2023 |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| , | Acquired by eurifins, Sep 2024 | |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| IBA Analytics | , | Website gone Jul 2015 |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| , | Acquired by Ligthouse Lab Services | |
| , | ||
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Biotel | , | Acquired by CardioNet, 2010 |
| , | Renamed First Atom Therapeutics | |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| Quench Bio | , | Wound down Mar 2021 |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| Antisoma | , | Became investment company |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| OD-OS | Teltow, Germany | Retinal Laser |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Tal Medical | , | Gone |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| Aerovance | , | Gone, don’t know where |
| EsbaTech | , | Bought by Alcan |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| Piramal | Morpeth, UK | CDMO |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Molsid | Lyon, France | Fluorogenic Probes |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Tgen Tech | , | Renamed Annoviant |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| MolPlex | , | Insolvent, 2016 |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| AbGenomics | , | Renamed Altrubio |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| Anfiro | , | Shut down Dec 2019 |
| , | Website down Jul 2025 - Dec 2025 | |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| Valor Biotechnology | , | Renamed Roivant |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Biophytis | Paris, France | Therapies for aging diseases |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| Excaliard | , | Bought by Pfizer 2011 |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| Kuroki Consulting | , | Shut down 2020 |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| Vernay | Griffin, GA | Fluid Control Solutions |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| , | Website taken over Mar 2026 | |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Roche | Mississauga, ON | Small Molecules |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| Altasciences | Laval, QC | Contract Research |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Vicus Therapeutics | , | Gone 2019 |
| ViraCyte | , | Renamed AlloVir |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Waters | Milford, MA | Chromatography & Chemistry |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Actium Biosystems | , | Gone 2013 |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| , | Website down Dec 2025 - Apr 2026 | |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| AngioChem | , | All employees gone, no info, presumed gone |
| QuatRx | , | Acquired by Shionogi, 2017 |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| Inexia | , | Acquired by Centessa |
| ProPharma Group | Westlake, OH | Consulting |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Inventprise | Redmond, WA | Vaccines |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| Heraeus Medical | Changshu, China | Medical Devices |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| Mott | Farmington, CT | HPLC system components, Filtration |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| Bayer | Mexico City, Mexico | Small Molecules |
| Gilead | Edmonton, AB | Small Molecules |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Apcer Life Sciences | London, UK | Consultants |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| EpitoGenesis | , | Gone 2017 |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Wokingham, UK | Analytical Services | |
| New Brunswick Scientific | , | Merged into Eppendorf |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| Rezolute | Redwood City, CA | Biologics |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| , | Website down Aug 2025 - Jan 2026 | |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| Cell Technology | , | Acquired by ICT |
| Evofem Biosciences | San Diego, CA | Women's health |
| Immune Technology Corp | New York, NY | Virology research products |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Advaned Viral Research | , | Shut down 2009 |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| Safecor Medical | , | Shut down Apr 2021 |
| Medtronic | Warsaw, IN | Medical Devices |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| VaxNewMo | , | Renamed Omiose |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| Dynatherm Medical | , | Shut down 2012 or later |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Zomanex | , | Gone Oct 2019 |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| INEX Pharmaceuticals | , | Gone May 2007? |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| , | Acquired by BioIVT, Aug 2024 | |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Invenra | Madison, WI | Antibodies and their derivatives |
| Delpharm | Tours , France | Contract Manufacturing |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| , | Renamed Turing Medical | |
| Premier Biomedical | , | Pivoted out of life science |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Afferon | , | Gone, no info |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| Jet Life Sciences | Hyderabad, India | APIs |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| Sequoia Pharmaceuticals | , | Folded |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| Inno Biologics | , | Website gone Jun 2020 |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Regenica Biosciences | , | Gone Nov 2020 |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| , | Website down Jan 2026 - May 2026 | |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Vericel | Ann Arbor, MI | Cellular Products |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
| Genemo | , | Seems inactive, Jul 2024 |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| MicrofluidX | , | Renamed MFX |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| Bioserv America | , | Shut down Aug 2024 |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| Kendle | , | Acquired by INC Research 2011 |
| GlycoRegImmune | , | Changed name to GRI |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| restor3d | Durham, NC | 3D printed implants and devices |
| Stromedix | , | Bought by Biogen Idec 2012 |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| BioParadox | , | Shut down Dec 2017 |
| Sterling | Concord, ON | Medical Device Contract Manufacturing & Development |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| US Genomics | , | Now PathoGenetix |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| Calcionics | , | Shut down 2010 |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| , | Selling pipeline, winding down Jul 2025 | |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Abgent | , | Renamed Abcepta, 2019 |
| , | Website down Nov 2025 - Feb 2026 | |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Bioasis Technologies | , | Closing down Jun 2023 |
| , | Company gone Nov 2023, website taken by a game | |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Zylacta | , | No news 2015 - Oct 2024 |
| Y's Therapeutics | , | Website Gone |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| CardioCanary | , | Founders gone. Doubt it's active |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Heragen | , | Gone |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Curia | Albany, NY | Contract Research, Development, Manufacturing |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| Crown Bioscience | Taicang, China | Drug Development |
| CyBio | , | Merged into Jena, Jul 2014 |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| , | Acquired by Stryker, Sep 2024 | |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| CeNeRx | , | Shut Down, 2013 |
| Vitrology | , | Acquired by SGS, May 2012 |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| Caris Life Sciences | Irving, TX | Diagnostics |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| Sepiatec | Berlin, Germany | Separation Systems |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| bioMerieux | Durham, NC | Diagnostics |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| Sanofi | Paris, France | Small Molecules |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| Medrobiotics | , | Bankrupt, May 2024 |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| Medochemie | Limassol, Cyprus | Generics |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| , | Shut down Feb 2026 | |
| Targinta | Lund, Sweden | Antibodies for Cancer |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Kuano | Cambridge, UK | AI Drug Discovery |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Cure Foreward | , | Services suspended, May 2017 |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| Xtuit | , | Gone Jul 2018 |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Gensia Sicor | , | Renamed Sicor |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| , | No news 2017 - Apr 2026 | |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| DM Clinical Research | Houston, TX | Clinical Research |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| Pentapharm | Basel, Switzerland | APIs |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Celerion | Belfast, UK | Clinical Research |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| Kymanox | Morrisville, NC | Life Science Consulting |
| DNALite Therapeutics | , | Renamed Particella |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| Apic Bio | , | Shut down Jan 2024 |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| Sundia | , | Part of BioDuro |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Antigenics LLC | , | Now Agenus |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| GenSensor | Nantes, France | Process Analytical Technology |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| DL Develop | , | Website gone, Dec 2018 |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Solvanix | , | Shut down Nov 2023 |
| XtalPi | Shenzhen, China | AI Drug Design |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| , | Website down Oct 2025 - Feb 2026 | |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| , | Website down Jul 2025 - Jan 2026 | |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Apollomics | Foster City, CA | Cancer medicines |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Emergo by UL | Austin, TX | Medical device consulting |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| PowderMed | , | Acquired by Pfizer 2006 |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| Indena | Milan, Italy | CDMO |
| Therorna | Beijing, China | RNA Therapies |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| LyoGo | , | Website gone, all employees gone |
| Profusa | Emeryville, CA | Real-time biosensors |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| , | Website down Dec 2025 - Feb 2026 | |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| Getinge | Getinge, Sweden | Medical Technology |
| CompleGen | , | Shut down Aug 2021 |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Ectycell | , | Part of Cellectis |
| NextGen Sciences | , | Defaulted, sued by employees |
| Piramal | Rabale, India | CDMO |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| Roche | Burgess Hill, UK | Diagnostics |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| SOCIUM | Tokyo, Japan | Contract Research |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| Lean Biologix | Norfolk, MA | Consulting |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Ansh Labs | Webster, TX | Diagnostics Products |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| , | Website down Jan 2026 - May 2026 | |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| Vistin Pharma | Oslo, Norway | Generics |
| PharmacoFore | , | Now Signature Therapeutics |
| Salus Bioscience | , | Forfeited in CA |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| Macusight | , | Effectively acquired by Santen, 2008 |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| , | Website down Jun 2025 - Dec 2025 | |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| Abbott | Singapore, Singapore | Diagnostics |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Nanoferix | , | Renamed Pendant Biosciences |
| , | Website down Dec 2025 - Apr 2026 | |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| Inspirata | Tampa, FL | Cancer Insights |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Norgine | Milan, Italy | Specialty Pharma |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Oncorus | , | Liquidated, Jun 2023 |
| AstraZeneca | New Haven, CT | Biologics |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Humanyx | , | No website, Seems gone |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Imalux | , | Ceased Operations, Apr 2014 |
| , | Main employees gone for months as of Nov 2025 | |
| Michigan Clinical Research Institute | , | |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Hutchmed | Hong Kong, China | Oral drugs |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Iconovo | Lund, Sweden | Inhalation Technology |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Microfluidics | Westwood, MA | High shear fluid processors |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| TR Biosurgical | , | Website Taken Over |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| ConjuChem | , | Bankrupt 2011 |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| OxOnc Development | , | Website gone Apr 2018 |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| Kembiotix | , | No info, Aug 2022 |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| 1859, Inc. | , | Shut down Jul 2023 |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Talis Biomedical | , | |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| , | Acquired by Olon, 2024 | |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Picoseq | , | Renamed Depixus |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Cytovale | South SF, CA | Sepsis Detection |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| Genova Clinical Research | , | Gone, 2014 |
| , | Website down May 2025 - Dec 2025 | |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| ProPharma Group | Windsor, ON | Consulting |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Noscira | , | Liquidated |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| DiaGenic | , | Switched to energy sector |
| Chromtech | Apple Valley, MN | Chromatography Products |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| Ximedica | San Francisco, CA | Medical Device Services |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| Solexa | , | Merged with Illumina 2006 |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Medtronic | North Haven, CT | Medical Devices |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| EhmetDx | , | Renamed Ehmet Health |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| Z-Factor | , | Centessa Company |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| 3B BlackBio | Bhopal, India | PCR products |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| Glysantis | , | Shut down Late 2020 |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| Tethys Bioscience | , | Shut Down, late 2013 |
| D-Pharm | , | Website Gone, Aug 2016 |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| NeuroPharm | , | Liquidated 2010 |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Novarad | Provo, UT | Imaging Software and Technology |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| APSciences | , | Website gone Aug 2022 |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| Sarstedt | Nümbrecht, Germany | Lab products |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| Harmony Labs | , | Now Ei |
| Medrio | San Francisco, CA | Clinical Trial Software |
| , | No news Jun 2021 - Jan 2026 | |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| ClinOne | Needham, MA | Clinical Patient Platform |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Acuvax | , | Pivoted to investments, 2014 |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Santen | Osaka, Japan | Ophthalmics |
| Echo | San Diego, CA | Microscopy |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| , | Website down Aug 2025 - Jan 2026 | |
| Iktos | Paris, France | AI for New Drug Design |
| Emmes | Rockville, MD | Clinical Research Organization |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Arbovax | , | Gone |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| Catalyst Clinical Research | Cheshire, UK | Clinical research solutions to the global biopharmaceutical industry |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| BioArra | , | Bought by VWR Nov 2016 |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Targenics | , | No website Mar 2020 |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| DNASTAR | Madison, WI | Molecular Biology Software |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| Veravas | Oakdale, MN | Diagnostics |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Neurotronik | , | Most employees moved to InnerPulse |
| Delta4 AI | Schindellegi, Switzerland | AI Drug Discovery |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| , | Website down Dec 2025 - Apr 2026 | |
| Westat | Rockville, MD | Clinical trial design, management, services |
| InVasc Therapeutics | , | Shut down 2012 |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Avaxia Biologics | , | IP acquired by Circle33 |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Bolder Biotechnology | Boulder, CO | Biologics |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| InCytu | , | Website gone Jul 2015 |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| Laureate Pharma | , | Acquired by Gallus |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| Stryker | Portage, MI | Medical Devices |
| United Neuroscience | , | Renamed Vaxxinity |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Novotech | Melbourne, Australia | Clinical Research |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Mediatech | , | Now Cellgro |
| General Oncology | Brookline, MA | Cancer Therapies |
| Epiomed Therapeutics | , | Gone |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Idience | Seoul, Korea | Cancer Therapies |
| Vie Diagnostics | , | Renamed Phoresa |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| , | Website down Jan 2026 - May 2026 | |
| Curia | Hayward, CA | Contract Research |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Valitor | Berkeley, CA | Protein therapeutics |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| AB Science | Paris, France | Small Molecules |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| , | Acquired by mining company; fka Anew Medical | |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| Grunenthal | Origgio, Italy | Small molecules |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Quest Clinical Research | , | Now part of eStudysite |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| Zensun | , | Website gone Jan 2019, Chinese company |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Genetron Health | Beijing, China | Diagnostics |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Genoma | , | Website gone May 2021 |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| Talecris Biotherapeutics | , | Merged with Grifols |
| QSV Biologics | , | Website Gone |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| Torpedo Bio | , | |
| Bakersfield, CA | Clinical Trials | |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Thermo Fisher | Bend, OR | CDMO |
| ChondroGene | , | Now GeneNews |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Vernacare | Worksop, UK | Surgical Devices |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Aeres Biomedical | , | Gone Jul 2013 |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| GenoSpace | Boston, MA | Platform for genomic data |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| iBridge Medical | , | Website gone Jan 2020 |
| Cogentis Therapeutics | , | No news 2017-2023 |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| Spring Discovery | , | Renamed Spring Science |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| XtalPi | Shanghai, China | AI Drug Design |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| PluriCell | , | Renamed LizarBio |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Genocea Biosciences | , | Winding Down May 2022 |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| Phenoquest | , | Website gone, Oct 2015 |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Abogen | Suzhou, China | mRNA |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| iCeutica | , | Seems gone, Jan 2022 |
| BGI | Kobe, Japan | Genetic Testing |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Formurex | Stockton, CA | Contract Research |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| , | Acquired by Arterex, Jun 2023 | |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Élancé Therapeutics | , | Bispecific Antibodies |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| Stasys Medical | , | Shut down Feb 2025 |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Promethera Biosciences | , | Renamed Callaion |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Axplora | Raubling, Germany | API CDMO |
| Synthon | , | |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| GemacBio | , | Renamed PolyNeuroS |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| , | Website down Jul 2025 - Dec 2025 | |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| Agenix | , | Gone, Website taken over |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Penwest | , | Bought by Endo |
| Rubicon Research | Thane , India | Generics |
| Innovative BioTherapies | , | Gone |
| Voitheia Bioscience | , | |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Sanovel | Istanbul, Turkey | Generics |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Adlon Therapeutics | , | |
| AssureRx | , | Renamed Assurex Health |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| Cytiva | Piscataway, NJ | Medical Devices |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Quartzy | Hayward, CA | Lab Management Software |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| West-Ward | , | Now part of Hikma |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Verana Health | San Francisco, CA | Clinical Database |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| CO.DON | Teltow, Germany | Cell Therapies |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Formation Bio | New York, NY | AI Drug Discovery |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| MMI Genomics | , | Assets bought by Neogen |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| VasoRx | San Diego, CA | RNA delivery |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| Kar Bioanalytical | , | Seem gone |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Akero Therapeutics | South SF, CA | NASH therapy |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Verasonics | Kirkland, WA | Research Ultrasound |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| Velquest | , | Bought by Accelrys Jan 2012 |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| Opsonix | , | Shut down May 2018 |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| Signalife | , | Renamed Heart Tronics |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| , | No news Aug 2019 - Jan 2026 | |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| NX Development | Lexington, KY | Brain Imaging |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| Western States Biopharmaceuticals | , | Website Taken Over |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| Pear Bio | London, UK | Cancer Treatment Selection |
| Molecular Detection Inc | , | Gone 2016 |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| CTIBIOTECH | Meyzieu, France | Tissue Sample |
| Genomics | Oxford, UK | Human Genetics Platform |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| DiagnoSearch | Thane, India | Clinical Research |
| HebeCell | Natick, MA | Cell Therapies |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| Piramal | Pithampur, India | CDMO |
| ProteinLinks | , | Seem gone |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| Theramex | London, UK | Women's Health |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Gencove | New York, NY | Genome Sequencing |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Solano Pharmaceuticals | , | Website gone |
| Chrysalis | Morrisville, NC | GMP Space |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Piramal | Lexington, KY | CDMO |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Chennai, India | Contract Development Organization | |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| Zumutor Biologics | Cambridge, MA | Biologics |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Stago | Gennevilliers, France | Diagnostics |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| Omeros | Seattle, WA | Small Molecules |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| Actavalon | , | Shut down Dec 2020 |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| , | Shut down Oct 2024 | |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| Coferon | , | Renamed BlinkBio |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| Gilead | Foster City, CA | Small Molecules |
| Afaxys | Charleston, SC | Women's Health |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| , | Website down Jan 2026 - May 2026 | |
| OXON | Madrid, Spain | Real World Evidence |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| Clear Image Technology | , | Now CIT Ortho |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| Getinge | Plewiska, Poland | Medical Technology |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| Nteryx | , | Changed name to Ardelyx |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| TG Therapeutics | Morrisville, NC | Biologics |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Eurogentec | Seraing, Belgium | Biologics |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| Steris | Mentor, OH | Contamination Control |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| CytoVera | , | Gone June 2017 |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Asarina Pharma | , | Winding down Jul 2024 |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| TearScience | , | Acquired by J&J, Nov 2017 |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| SalioGen Therapeutics | , | Shut down late 2024 |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| AsymBio | Jinshan, China | Biologics CDMO |
| PharmAbcine | Daejeon, Korea | Antibodies |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Spear Bio | Woburn, MA | Immunoassays |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| Zumutor Biologics | Bangalore, India | Biologics |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Celavie Biosciences | , | Shut down Mar 2024 |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| Cydan Development | , | Shut down Sep 2021 |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| Cherry Biotech | Paris, France | Organoid Culture |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| ChronTech Pharma | , | Became real estate company |
| CoRegen | Aspen, CO | Genetically Engineered T Reg Cells |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| Novonesis | Beijing, China | Enzymes |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| AVEO Oncology | Boston, MA | Small Molecules |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Tasso | Seattle, WA | Blood-collection products |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| ECI Biotech | , | Gone 2016 |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Twistnostics | , | Renamed Scanogen |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| FluoroPharma | , | Shell Company |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Bacthera | , | Liquidating, Feb 2025 |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| QuA Vodis | , | Gone |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| SIMR (Australia) Biotech | Shanghai, China | CNS Small Molecules |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| , | Merged with Vizgen, Oct 2024 | |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Cellf BIO | , | Website taken over Jan 2019 |
| , | Website down Dec 2025 - May 2026 | |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Tico Bio | , | Renamed Inso Biosciences |
| Evolve BioSystems | , | Renamed Infinant Health |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| JK Biopharma Solutions | , | Founder gone |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Akceli | , | Shut down, Sep 2004 |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Natera | San Carlos, CA | Prenatal Testing |
| , | Shut down Jul 2025 | |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| SomaServe | , | Renamed ViaNautis Bio |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| BioFluentLabs | , | Shut down July 2012 |
| TcLand Expression | , | Website Gone |
| Apath | , | No website update since 2014, Feb 2023 |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Yao Pharma | Chongqing, China | APIs, Generics |
| Cellink | Gothenburg, Sweden | Bioprinting |
| Bayer | Barcelona, Spain | Small Molecules |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| Almac | Souderton, PA | Pharmaceutical Services |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| , | Website down Aug 2025 - Jan 2026 | |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Ecopharm | , | Website down Feb 2021 |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| NS Pharma | Paramus, NJ | Small Molecule |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| Exactech | Gainesville, FL | Medical Implants |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Proteorex | , | Gone Nov 2017 |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Molecular Loop | Woburn, MA | NGS Technology |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| MicroVention | , | Now Terumo Neuro |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| DKP Genomics | , | Dissolved Jul 2025 |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| Unilife | , | Bankrupt, Apr 2017 |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| Psomagen | Rockville, MD | Genetic Sequencing |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| BA Sciences | Salem, NH | Analytical Services |
| Celsense | , | Shut down Dec 2021 |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Paris, France | Molecular Discovery Platform | |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| , | Acquired by Fujirebio, 2022 | |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Nodality | , | Gone |
| Synthace | London, UK | Development Software |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| Catamaran Bio | , | Winding down Jan 2024 |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| NEC Oncoimmunity | , | Renamed NEC |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Revolution Biomanufacturing | Canton, MA | mRNA, lipid nanoparticle CDMO |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| PepLib Biotech | Metuchen, NJ | Peptides |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Cognis Corp | , | Acquired by BASF 2010 |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| UVision 360 | , | Renamed Luminelle |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| Manhattan Pharmaceuticals | , | Gone |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Affivant | , | Part of Roivant |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Roxall | , | No news 2019 - May 2025 |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| Raytone Bio | , | |
| RION | Rochester, MN | Exosome Therapeutics |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Proscia | , | |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| , | No news 2019 - Apr 2026 | |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| Hypromatrix | , | Gone 2007 |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| Lacerta Therapeutics | , | Shut down May 2024 |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| , | Shut down Mar 2026 | |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Oncovista | , | Dormant 2016 |
| Tirupati | New Delhi, India | Generics |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Medivector | , | Gone late 2018 |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| RxGen | , | Renamed Virscio, Jan 2020 |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| ClinArt | , | Now ClinArt MENA |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| CSL Behring | King of Prussia, PA | Biologics |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| , | Renamed Cyclana Bio | |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Ona Therapeutics | Barcelona, Spain | Cancer Therapies |
| PROGEN | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Advanced Genetic Technologies | , | No info |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| MicroPort | Shanghai, China | Medical Devices |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| ArisGen | , | Only employee has four other jobs |
| Catalyz | , | Gone |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| , | Liquidated 2024 | |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Nabla Bio | Cambridge, MA | Antibody Design |
| , | No news 2021 - Sep 2025 | |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Leading Pharma | Fairfield, NJ | Generics |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Enesi Pharma | , | Renamed aVaxziPen |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| Abiologics | Cambridge, MA | Synteins |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| MetaMol Theranostics | , | Gone |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Axplora | Mourenx, France | API manufacturing |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| Mindshare Medical | , | Renamed RevealDx |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| RegeneMed | , | No longer active in CA as of 2014 |
| Enlibrium | , | Gone 2018 |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| , | ||
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| , | Renamed Racura Oncology, Dec 2025 | |
| Stago | Taverny, France | Diagnostics |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Zyomyx | , | Closed as of 2014 |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Simpirica Spine | , | Became Empirical Spine |
| Alera Labs | Durham, NC | Contract Research & Services |
| Genae Associates | , | Acquired by IQVIA |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| Psylo | , | Renamed Xylo, Jan 2025 |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| , | Website down Dec 2025 - Apr 2026 | |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| , | 16 years in, CMO is CEO elsewhere Dec 2025; fka Glycoregimmune | |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Tella | , | Website down May 2023 - Dec 2023 |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| Serentis | , | Website Gone |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Almac | Durham, NC | Pharmaceutical Services |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| mibe Arzneimittel | Brehna, Germany | Generics |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Elixir Pharmaceuticals | , | Gone |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
| Triage Wireless | , | Now named Sotera Wireless |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Summation Bio | , | Shut down May 2023 |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| Pharminox | , | Website gone, Aug 2017 |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| , | Acquired by IQVIA | |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| Cellink | Blacksburg, VA | Bioprinting |
| Aixlie Pharmaceuticals | , | No idea what happened |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| Tuevol Therapeutics | , | Gone by 2020 |
| Kirax | , | Website Gone |
| Weatherwax | , | Renamed General Proximity |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Ana-Gen Technologies | , | Gone post 2001 |
| Delta-Vir | , | Website down Mar 2023 |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| TreeFrog Therapeutics | Pessac, France | 3D Stem Cell Culture Technology |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| COR Clinical Research | , | Shut down after owner passed |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| South Coast Clinical Trials | , | Website gone |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| OncoQr | , | No news 2017 - Oct 2024 |
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| , | Website taken over Feb 2026 | |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| Indero | Montréal, QC | Dermatology Clinical Research |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| NKMax America | , | Renamed NKGEN Biotech |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| , | Website down Jan 2026 - May 2026 | |
| Launchpad Therapeutics | , | |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| , | No news 2021 - Apr 2026 | |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| , | Website down Aug 2025 - Jan 2026 | |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Anoixis | Natick, MA | Pharmacometric Services |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| Healx | Cambridge, UK | AI Drug Discovery |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| CROSSJECT | Dijon, France | Needle-free Injection |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| Insulete | , | Website gone, presumed inactive |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| Aviv Biomedical | , | Shut down 2018 |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| , | Website down Sep 2025 - Feb 2026 | |
| Sensys Medical | , | Old company, no website, presumed defunct |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| QL Biopharm | Beijing, China | Biologics |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Mendaera | San Mateo, CA | Medical Robotics |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| BioXpert | , | Website gone Mar 2017, employees gone |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| SVA | Madison, WI | Biotechnology Management Consulting |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| BioCydex | , | No info 2019 - Mar 2025 |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| Cytokinetics | South SF, CA | Small Molecules |
| , | Renamed KadisBio | |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Nesher Technologies | , | Shut down Oct 2017 |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| Apotex | Toronto, ON | Small Molecule Generics |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| , | Renamed Virchow | |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| NorthLinks Bio | , | |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| Mabimmune | , | Merged with Neurimmune |
| , | Pivoted to crypto Jan 2026 | |
| MediWound | Yavne, Israel | Wound & Burn Care |
| , | Now Nexus Spine | |
| Centricity Research | Toronto, ON | Clinical Research |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| AbBaltis | Kent, UK | Plasmas & Sera |
| Symbollon | , | Gone |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| Cambrian Bio | New York, NY | Small Molecules |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| , | Renamed Verge Medical, Mar 2025 | |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| Stago | Clarkston, GA | Diagnostics |
| Optovue | , | Renamed Visionix Sep 2021 |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| , | Website down Jan 2026 - May 2026 | |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| UniXell | Shanghai, China | Cell Therapy |
| Cytoskeleton | Denver, CO | Research Products |
| NeuroNano Pharma | , | Gone 2018 |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| NextCure | Beltsville, MD | Immune Therapies |
| , | Renamed Hermes Biosciences | |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| , | Website down Oct 2025 - Feb 2026 | |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| , | Website down Aug 2025 - Jan 2026 | |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Pathway Genomics | , | Renamed OmeCare |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Organon (2) | Jersey City, NJ | Women's Health |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Ossis | , | 3D-printed orthopedic implants |
| Quanticate | Bangalore, India | Clinical Research |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| LinKinVax | , | Rebranded as EnnoDC |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| Existence Genetics | , | Bankrupt Dec 2012 |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| , | Shut down Oct 2023 | |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| Dundee Cell Products | , | Renamed DC Biosciences |
| Vivex Biologics | Atlanta, GA | Tissues |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| Kirgen | Shanghai, China | Lab Supplies |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Pall | Port Washington, NY | Filtration |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| JABio | , | Shut Down May 2021 |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| Phase Forward | , | Bought by oracle |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| XO1 | , | Bought by J&J, Mar 2015 |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| Getinge | Suzhou, China | Medical Technology |
| , | Website down Dec 2025 - Apr 2026 | |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| Calibrant | , | Closed |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Genta | , | Liquidation 2012 |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Novotech | Bangkok, Thailand | Clinical Research |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| Applied Therapeutics | New York, NY | Small Molecules |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| Endothelix | , | Now owned by American Heart technologies |
| Metenova | ZZ, Sweden | Mixers |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| , | Website gone Feb 2026 - Apr 2026 | |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| Wheaton | , | Renamed DWK Life Sciences |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| Integer | Chaska, MN | Medical & Surgical Devices |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| alphaSyx Therapeutics | , | Gone |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| CorWave | Clichy, France | Blood Pumps |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| tiakis Biotech | Kiel, Germany | Biologics |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| nitec Pharma | , | Merged with Horizon Pharma |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Calzada | , | Renamed Polynovo |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| , | Website down Oct 2025 - Feb 2026 | |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| ProPharma Group | Raleigh, NC | Consulting |
| Clontech | , | Now Takara Bio |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Metabasis | , | Bought by Ligand |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| BiOM | , | Now BionX Medical |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| OBDURO Biotechnologies | , | never a registered CA business |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Calibra Medical | , | Acquired by JNJ 2012 |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Veeva Systems | Dublin, OH | Life Science Software |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| SEQENS | Ecully, France | APIs, Ingredients |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Catalyst Clinical Research | Wilmington , NC | Clinical research solutions to the global biopharmaceutical industry |
| G6 Spine | , | Gone 2017 |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| NeuroVista | , | Website Gone, President has new job |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| STC Biologics | Newton, MA | Services |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| , | Website down Jan 2026 - Mar 2026 | |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Atherotech | , | Shut down Feb 2016 |
| Zelos Therapeutics | , | No site |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| XBiotech | Austin, TX | Antibody Therapy |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| , | Website down Jan 2026 - May 2026 | |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| PeriGen | Cary, NC | Perinatal Devices |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| MOgene | St. Louis, MO | Genomic Services |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| RepRegen | , | Gone, 2014 |
| Aegea Biotechnologies | , | |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Tempered Biosciences | , | Absurd website has to be gone |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| Corza Medical | Shanghai, China | Surgical Devices |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Alibion | , | Website down May 2021 - Sep 2021 |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| , | Liquidation, Jun 2025 | |
| Lavipharm | Paris, France | Small molecules |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| , | Website down Jun 2025 - Dec 2025 | |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| Sebra | Tucson, AZ | Tube Sealer |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Bio-Detail | , | Website gone Feb 2023 |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| Doctor Pack | Bangalore, India | Packaging |
| SemBioSys | , | Bankrupt, Jul 2012 |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| Blu Biotech | , | Website down May 2023, CEO gone |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| Boragen | , | Renamed Reactive Biosciences |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| Heidelberg, Germany | Scalable Protein Production | |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Calmune | , | Liquidated |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| MSD | Leopardstown, Ireland | Small Molecules |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Totient | , | Acquired by Absci, Jul 2021 |
| Orbus Pharma | , | Website Gone |
| Sentien Biotechnologies | , | Shut down late 2021 |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| Parexel | Sheffield, UK | Clinical Research |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| Curia | Valladolid, Spain | Contract Development, Manufacturing |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| MedTrials | Dallas, TX | Clinical Trial Management |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| , | Website down Jul 2025 - Jan 2026 | |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| , | ||
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| Glenmark | Mumbai, India | Generic Small Molecules |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| Jetequip | Boucherville, QC | Fluid Handling |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Sopharma | Sofia, Bulgaria | Generics |
| Natus Medical | Middleton, WI | Medical Devices, software |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Accutome | , | Now part of Keeler |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Northstar Neuroscience | , | Dissolved |
| Droice | New York, NY | AI Clinical Data |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| Immunogen (1) | , | Renamed ImmunogenX |
| Resilience | San Diego, CA | Biomanufacturing |
| , | Small Molecule Therapies | |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| Sysmex | Tokyo, Japan | Diagnostics |
| Doer Biologics | Hangzhou, China | Biologics |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| Sopherion | , | Website taken over, Mar 2017 |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Novonesis | North Rocks, Australia | Enzymes |
| Ally Therapeutics | , | Shut down early 2021 |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| |
Rhymney, UK | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| Analiza | Cleveland, OH | Physicochemical Services |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| PulmoGeniX | , | No business filings 2016-2020 |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| Rosedale Medical | , | Now Intuity Medical |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| Abbott | Irving, TX | Devices |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| Chesapeake Biological Labs | , | Now known as Cangene |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| , | Acquired by HB Fuller, Jul 2023 | |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| Allux Medical | , | Shut down, Feb 2009 |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Protelica | , | Dissolved, Dec 2006 |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Acumed | Hampshire , UK | Medical Implants |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| Intellirod Spine | , | Sold Assets late 2020 |
| , | Website down Sep 2025 - Dec 2025 | |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| CORONIS | Athens, Greece | Clinical Studies |
| Abbott | Mississauga, ON | Diagnostics |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| Unither Pharmaceuticals | Paris, France | CDMO |
| nplex biosciences | , | Renamed Nomic Bio |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| Leucid Bio | London, UK | Cell Therapy |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Getinge | Fairfield , NJ | Medical Technology |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Avecia | , | Bought by Nitto Denko |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| NeoCura | Beijing, China | Personalized Vaccines |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| NantHealth | El Segundo, CA | Diagnostics |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Epic Pharma | Laurelton, NY | Generics |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| X2 Pharma | , | Website Gone |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Metabolex | , | Now CymaBay Therapeutics |
| Vali Nanomedical | , | Gone 2016 |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| Labshire | Cambridge, MA | Laboratory Consulting |
| Cdymax | Bangalore, India | APIs |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Xcelthera | , | Shut down, Apr 2021 |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| Dipharma | Baranzate, Italy | APIs, Generics |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Tanai Therapeutics | , | Obesity Treatment |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| Genex Pharma | Mumbai , India | Generics |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| , | Subsumed into Synoptics | |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| Hasten Pharma | Hefei, China | Small Molecules |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| Assurance Scientific Laboratories | Birmingham, AL | Molecular Technologies |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Veeva Systems | Shanghai, China | Life Science Software |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| NextPharma | Limay, France | Contract Research & Development |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| Avalyn Pharmaceuticals | Cambridge, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| Salvat | Barcelona, Spain | Small Molecules |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| ImmunoBiochem | , | No news 2018 -2023 |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Macrogen | , | Renamed Psomagen, 2019 |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| ADMA Biologics | Ramsey, NJ | Biologics |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Opentrons | New York, NY | Lab Automation Robots |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Grunenthal | Aachen, Germany | Small molecules |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| Genera Medix | , | Apparently sold all products |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| , | Website down Dec 2025 - Apr 2026 | |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| Bionsight | Chuncheon, Korea | Database For Research |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Molecular Logix | , | Gone, Dec 2018 |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Onorach | Dundee, UK | Clinical Trial Management |
| Therix Medical | , | Seems gone |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| Life Stem Genetics | , | Basically gone |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Geron | Foster City, CA | Small Molecule |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| Affinimark Technologies | , | Gone |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| InnoVoyce | Boston, MA | ENT Lasers |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| , | Acquired by Generic Specialties, May 2016 | |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| Nocimed | , | Renamed Aclarion |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| |
Mississauga, ON | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| Innerpulse | , | Gone maybe 2013 |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| InnoCare | Beijing, China | Cancer Treatments |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| Madeira Therapeutics | , | Gone. No info |
| Biokit | , | Rolled into Werfen |
| Avecris | Singapore, Singapore | Gene Delivery |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| , | Filings late Mar 2025 - Feb 2026 | |
| Sanofi | Haverhill, UK | Small Molecules |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Atanse | , | Website gone, May 2018 |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| ProPharma Group | Deerfield, IL | Consulting |
| , | Website down May 2025 - Dec 2025 | |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Roche | Basel, Switzerland | Small Molecules |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| Optherion | , | Sold Assets, Still Exists |
| Delpharm | Gaillard, France | Contract Manufacturing |
| R/D Clinical Research | , | Website Gone |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| Serometrix | , | More of an aspiration than a company |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| Cibiem | , | Shut down May 2021 |
| Avam | Odessa, FL | Clinical Diagnostics |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Pfizer | Puurs, Belgium | Packaging |
| Virvio | , | Gone Feb 2020 |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| , | Acquired by Alcon, Sep 2025 | |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| Novotech | Hong Kong, China | Clinical Research |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| TCXpress | , | Renamed BlueSphere Bio |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| Active Pass Pharmaceuticals | , | Gone |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Celula | , | Acquired by NeoSeq |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| , | Assets acquired by Alexion, Feb 2011 | |
| NeuroproteXeon | , | Gone 2021 |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Yposkesi | , | part of SK pharmteco |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Alphatec Spine | , | Renamed Atec Spine |
| Heart Tronics | , | Effectively defunct after scandal |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| VasoNova | , | Acquired by Teleflex Medical |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Arstasis | , | Appears Gone Sep 2017 |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| CelerDx | , | Tiny startup that went nowhere |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| CRIO | Boston, MA | eClinical Software |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| Endovasc | , | Bankrupt 2008 |
| DNAMx | , | Renamed Adela |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Octant Biotech | Emeryville, CA | Small Molecules |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ViThera Pharmaceuticals | , | Gone 2017 |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| preclinics | Potsdam, Germany | Contract Research |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| Action Pharma | , | Abbott acquired product, 2012 |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| Genestack | Cambridge, UK | Genomics operating system |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| BioMarin Pharmaceutical | London, UK | Biologics |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Atlas Genetics | , | Renamed Binx Health |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Ipsen | Sumter, SC | Biologics |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Curexsys | , | Dissolving, Jul 2024 |
| Gran Med | , | Gone |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Berg Pharma | , | Now just Berg |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| Infinitopes | Oxford, UK | Vaccines |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Bioquanta | , | Gone 2013 |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| Groton Biosystems | , | Gone before Jun 2015 |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Alaeras | , | Dissolved Jan 2014 |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| , | Renamed AtaiBeckley | |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Nura | , | Acquired by Omeros |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Naveris | Waltham, MA | Cancer Diagnostic |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Eurand | , | Now Aptalis |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| C/M/C Biologics | , | Now CMC Biologics |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Healogix | Doylestown, PA | Consulting |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Qlucore | Lund, Sweden | Visualization Software |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| Getinge | Englewood, CO | Medical Technology |
| Orochem | Naperville, IL | Reagents, Automation |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Trigemina | , | Shut down Aug 2020 |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| , | Part of ICE Pharma | |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Tolerx | , | Shut Down 2011 |
| GeneFab | Alameda, CA | Gene Therapy Services |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Cira Discovery | , | Website copyright 2003 |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Antitope | , | Now part of Abzena |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| EmpowerPharm | , | Shut down |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| Laborie | Portsmouth, NH | Medical Devices |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Remora Therapeutics | , | Shut down 2021 |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| ErVimmune | Lyon, France | Cancer Vaccines |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Newcastle, WA | Contract Chemistry Services | |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| , | Shutdown Oct 2025 | |
| Cognosetta | , | Gone 2021 |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| STX-Med | , | Renamed Cefaly |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| , | Acquired by Novacyt Group | |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| Nuevolution | , | Bought by Amgen May 2019 |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| Procept BioRobotics | San Jose, CA | Aquablation |
| , | Gone Jan 2025 | |
| NeuroVasx | , | No website May 2019, founded 1997 |
| Sterling | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| , | Website down Oct 2025 - Feb 2026 | |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| Pharmaron | Hertfordshire , UK | R&D Services |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| Akela Pharma | , | Now PharmaForm |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| Cyberval | , | Seems inactive Feb 2024 |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| Abnovel | , | Gone Jul 2010 |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| Cymbiotics | , | Gone 2019-2020 |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Getinge | Delft, Netherlands | Medical Technology |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Allometra | , | Gone |
| MantaBio | Beverly, MA | Real-time PCR System |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| Genuiti Therapeutics | , | |
| Tisucor | , | Shut down Feb 2020 |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| Piramal | Ennore, India | CDMO |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Revotek | , | Website down May 2023 - Sep 2023 |
| Qualicaps | Whitsett, NC | Capsules |
| Diversa | , | Merged with Celunol to become Verenium |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| , | Acquired by Instem, Jul 2025 | |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| CATO SMS | , | Renamed Allucent, May 2022 |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| MWG Biotech | , | Owned by Eurofins |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| Inference | Pune, India | Clinical Trial Services |
| Vista Scientific | , | Shut down Dec 2015 |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| Biopar | , | Gone? |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| DanPET | , | One guy, Feb 2024 |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Mitokine Bioscience | , | Seems to be a research library now |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| Velomedix | , | Shut down 2014 |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Aracea Therapeutics | , | No website Aug 2022 |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| Cryoniss | Deeside, UK | Bio Banking |
| , | Renamed PsiThera, Dec 2025 | |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| , | Renamed Kyntra Bio, Jan 2026 | |
| One Drop | , | Gone Dec 2024 |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| , | Website gone Feb 2026 | |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| Wellinks | New Haven, CT | Portable Nebulizer |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| XtalPi | Beijing, China | AI Drug Design |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Curia | Buffalo, NY | Contract Research |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| InterX | , | Acquired by NeoTX, May 2022 |
| Essential Pharma | Egham, UK | Generics |
| AniLocus | Germantown, MD | Preclinical CRO |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| Pique Therapeutics | , | Shut down Dec 2020 |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Avistone | Beijing, China | Precision Oncology |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Novoresearch | , | Gone 2014 |
| Chromocyte | , | |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| Ativa Medical | , | Renamed Immune IQ? |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| BioMAS | , | Ceased operating, Jul 2016 |
| Eos Biotechnology | , | Gone 2005 |
| , | Website down Aug 2025 - Jan 2026 | |
| Curia | Origgio, Italy | Contract Development, Manufacturing |
| IncellDx | , | Renamed HealthBio AI |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| Tunnell Consulting | Berwyn, PA | Consulting |
| Riboxx | Dresden, Germany | RNA Products |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| Biolab Pharma | Mississauga, ON | Small Molecules |
| Paige | New York, NY | AI Pathology |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| , | Acquired by Instem, Jul 2025 | |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| MyOme | Palo Alto, CA | Genomic Analysis |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| Rose Research Center | Raleigh, NC | Clinical Research |
| Cygene Labs | , | Gone |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Grunenthal | Quito, Ecuador | Small molecules |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Gossamer Bio | San Diego, CA | Small Molecules |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Ackley Hartnett | Moorestown, NJ | Tablet Machines |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| Corcym | London, UK | Implants, Instruments |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| GeneVivo | , | Unknown Fate |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| DNA Worldwide | Frome, UK | DNA Testing |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Acrongenomics | , | No info since 2013, seems gone |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| imarc | , | Acquired by Avania, Jun 2021 |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| , | Shut down late 2025 | |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Glialogix | , | Gone Nov 2017 |
| RS Medical | Vancouver, WA | Medical Devices |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| Medicomp | , | Renamed ReactDx |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| OcuDyne | , | AMD Medical Device |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Gilead | Mississauga, ON | Small Molecules |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| CPI Global | , | Website gone Jun 2020 |
| Oncology Clinical Research | , | Gone |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| Xcede Technologies | , | Gone Jun 2020 |
| Algenix | , | MN Business revoked, Mar 2004 |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| Xeris Biopharma | Chicago, IL | Injectables |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| Stago | Asnières sur Seine, France | Diagnostics |
| Hana Biosciences | , | Now Talon Therapeutics |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| PPL Therapeutics | , | Sold in 2003 |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| Apollo Spine | , | Renamed G6 Spine |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| CellXplore | , | Gone |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Kiecana Clinical Research | , | Now KCR |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| Lab Owl | , | Part of Inflexion Point |
| Grid Biosciences | New Territories, China | Vaccines |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Getinge | Hechingen, Germany | Medical Technology |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| AGI Therapeutics | , | Bought by Videra |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| RK Pharma | Pearl River, NJ | Generics |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Provecs Medical | , | Gone Nov 2019 |
| Cellnovo | , | Bankrupt, Jul 2019 |
| Gene Logic | , | Bankrupt |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| , | Website down Oct 2025 - Feb 2026 | |
| NIOX | Uppsala, Sweden | Asthma management device |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| Bluegrass Vascular | San Antonio, TX | Vascular access system |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Baxter | Alliston, ON | Medication Delivery |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| AJES Life Sciences | , | Renamed L2P Research |
| Macrocure | , | Merged into Leap Therapeutics |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| Kimer Med | Nelson , New Zealand | Antivirals |
| 3DBiopsy | , | Renamed Triopsy |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Palmaz Scientific | , | Bankrupt, 2016 |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Terumo Medical | Somerset, NJ | Medical Devices |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| AndroScience | , | Ancient website, no news 2014-2023 |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| APT Therapeutics | , | Shut down Mar 2019 |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| Antios Therapeutics | , | Shut down Feb 2023 |
| PrognosDx Health | , | Website gone Jun 2016 |
| Adheren | , | Gone, 2016 |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| IQVIA | San Diego, CA | Clinical Research |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Piramal | Aurora, ON | CDMO |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| , | Merged into Meridian Bioscience | |
| Silence Therapeutics | London, UK | RNAi |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Aliri | Loos, France | Contract Mass Spec |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| NTRC | , | Now Oncolines |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| , | Website down Oct 2025 - Feb 2026 | |
| GenQual | , | Inactive, Jun 2017 |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| Stago | Marseille, France | Diagnostics |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Abselion | Cambridge, MA | Biologics Quantification |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| LFB | Paris, France | Plasma derived drug products |
| Aspreva | , | Acquired by Vifor Pharma |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Verge Genomics | South SF, CA | Algorithm-based Drug Discovery |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Asensus Surgical | Durham, NC | Robot surgical system |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Alfasigma | Bologna, Italy | Small Molecules? |
| , | Website down Jan 2026 - Apr 2026 | |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| NTC | Milan, Italy | Generics |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| Glen Research | Sterling, VA | Oligos |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| Helix | San Mateo , CA | Genetic Testing |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| CytoMol (2) | , | SF-based, Looks gone |
| Piramal | Riverview, MI | CDMO |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| SoftGenetics | State College, PA | Software for genetic analysis |
| Sanovel | Silivri, Turkey | Generics |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Syngene International | Bangalore, India | Contract Research |
| Precision Research Institute | , | Shut down Apr 2024 |
| Minakem | Dunkerque , France | API Manufacturing |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Waterford, UK | Medical Device Contract Manufacturing | |
| Cirina | , | Merged with Grail, May 2017 |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| Microbiotix | Worcester, MA | Small Molecules |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| Taligen Therapeutics | , | Acquired by Alexion |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Peplin | , | Acquired by Leo Pharma 2009 |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| Epigenesis Pharmaceuticals | , | Gone |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Stealth Therapeutics | , | Gone |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| , | Liquidating Jan 2026 | |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| , | Liquidating, Sep 2025 | |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| Actis Biologics | , | Gone |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Stryker | Salt Lake City, UT | Medical Devices |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Cytiva | Tokyo, Japan | Medical Devices |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| PsiThera | Watertown, MA | Oral Small Molecules |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Curia | Rozzano, Italy | Contract Development, Manufacturing |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| PepVax | , | Gone 2024 |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Nusano | Valencia, CA | Radioisotopes |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| OverT Bio | New York, NY | Cell Therapy |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| Lucena | , | Failed |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| , | Website down May 2025 - Dec 2025 | |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Sprna | , | Website gone Jan 2020, no info |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| Integra LifeSciences | Boston, MA | Medical Devices |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| Proteins and Peptide Management | , | Now Adocia |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| Sinovac Biotech | Beijing, China | Vaccines |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| Ximedica | Providence, RI | Medical Device Services |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Acidophil | , | Gone late 2022 |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Semaphore Solutions | Victoria, BC | Lab Software |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| Concordia Healthcare | , | Now Concordia International |
| , | Acquired by Avania, Oct 2024 | |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| VedaLab | Cerisé, France | IVD rapid tests |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| Sicor Biotech | , | Bought by Teva 2004 |
| Vante BioPharm | , | Rebranded at Sebra |
| Signant Health | Horsham, PA | eClinical Solutions |
| Vascular Technology | Nashua, NH | Surgical Devices |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| Proteologics | , | Apparently Gone |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| Metrochem | Hyderabad , India | APIs |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Sirius Genomics | , | Gone |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| Core Prognostex | , | Seems inactive |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| Ocis Biotechnology | , | |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| Nile Therapeutics | , | Merged with Capricor |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Promosome | , | Gone |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| DoveTree Medicines | , | |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| CoAxia | , | Closed down Spring 2013 |
| TissUse | Berlin, Germany | Multi Organ chip |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Spirometrix | , | Renamed Spirosure |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Biorelate | Manchester, UK | AI Data Curation |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| superDimension | , | Acquired by Covidien May 2012 |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| Isis Biopolymer | , | Website taken over |
| Elanex Pharmaceuticals | , | Gone |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| MiniVax | , | Gone Jan 2016 |
| Vista.ai | Palo Alto, CA | MRI Software |
| Resilience | Mississauga, ON | Biomanufacturing |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| Karius | Redwood City, CA | Diagnostics |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| Steba Biotech | , | Renamed ImPact Biotech |
| Axya medical | , | Gone 2012 |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| CrelioHealth | Columbia, MD | LIMS |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| Meditrial | New York, NY | Clinical Services, Software |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Perlegen | , | No Site |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| , | Shut down Sep 2025 | |
| SynapDx | , | Shut down, Mar 2017 |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| Peptimmune | , | Liquidated 2011 |
| Mindflow Design | , | Now part of MPE |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Curl Bio | , | Shut down Feb 2020 |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Neuromatters | , | Shut down Dec 2019 |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| , | Shut down 2024 | |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| , | Dissolved, Apr 2024 | |
| Certego Therapeutics | , | Seems gone May 2023 |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| AdvaStim | , | Shut down, Dec 2017 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| TCG GreenChem | Ewing, NJ | |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Pfizer | Clondalkin, Ireland | Biologics |
| SEQENS | Pune, India | Analytical method validation, API development |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| CeQur | Greenville, SC | Insulin pump |
| AdrenaCard | , | Gone 2019 |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| Gastrotech | , | Now Rose Pharma |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Halo Genomics | , | Bought by Agilent |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| Norgine | Vienna, Austria | Specialty Pharma |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Affigen | , | Liquidating Fall 2019 |
| , | Shut down Jul 2025 | |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| Veryan Medical | Galway, Ireland | Helical Stent |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| Apofore | , | Shut down, Dec 2015 |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| Alimentiv | San Diego, CA | Clinical Services |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Aztech Sciences | , | Website gone Jun 2021 |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| Parcell Labs | , | Website Gone, Oct 2016 |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| US Labs | , | Bought by Labcorp |
| Avax Technologies | , | Gone |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| , | Website down Sep 2025 - Dec 2025 | |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Zenosense | , | No website, shell company Nov 2020 |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| VitalScientific | , | Analytical Systems for Diagnostics |
| Interferon Source | , | Bought by PBL Assay Science |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Alcon | Mississauga, ON | Eye Care Products |
| Curia | Buffalo, NY | Contract Research |
| Lindus Health | London, UK | CRO |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| , | ||
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| , | Website down Aug 2025 - Dec 2025 | |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Surgisense | , | Presumed gone |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| Dirui Industrial | Changchun, China | Automated Assays |
| Sanarus | , | Acquired by Hologic, 2020 |
| Etubics | , | Rolled into ImmunityBio |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| Celregen | Hangzhou, China | iPSC |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| Cilag | , | Joined J&J 1959 |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| , | Website down Dec 2025 - Apr 2026 | |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Immunome | Exton, PA | Cancer Immunotherapy |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Sure Genomics | , | Gone 2014? |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| , | Renamed Singulera, Nov 2025 | |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| Kulira Technologies | , | Website Gone Oct 2016 |
| Savant HWP | , | Gone 2019 |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Concerto HealthAI | , | Renamed ConcertAI |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| August Bioservices | Nashville, TN | Research & Development Services |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| MJ Biopharma | Mumbai, India | Generics |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| Partner Therapeutics | Lexington, MA | Biologics |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| Cureport | Worcester, MA | Nanomedicines |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| yuFlu | , | No website, no info Feb 2021 |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| , | Renamed Pixl.bio, Nov 2025 | |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| , | No news 2019 - Sep 2025 | |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Epigen | , | Renamed Egenix, 2002 |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Abbott | Princeton, NJ | Diagnostics |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| sRNA Dx | , | aka sRNAlytics |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Abcellute | , | Dissolved, Sep 2016 |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| , | Renamed Transcend, Feb 2022 | |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| EXO Biologics | Liège, Belgium | Exosomes |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Advarra | Columbia, MD | Regulatory Consulting |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| McGee Pharma | , | Merged with Pharmalex |
| CTK Biotech | Poway, CA | Diagnostics |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| Genstruct | , | Now Selventa |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| Avadel Pharmaceuticals | Chesterfield, MO | 505(b)(2) product |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| Syneos Health | Morrisville, NC | Clinical Development |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| , | Website down Aug 2025 - Jan 2026 | |
| Semafore Pharmaceuticals | , | Gone? |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| APIE Therapeutics | , | Gone Jun 2025 |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| , | Part of Normec | |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| , | Renamed LeonaBio, Jan 2026 | |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| Myriad Pharmaceuticals | , | Now Myrexis |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| NK CellTech | Shanghai, China | Cell Therapies |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| TaiwanBio | , | Website gone Oct 2021 |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Synomics | , | Now Smithers Pharma Services |
| BioMap | Palo Alto, CA | AI Models |
| Cerimon Pharmaceuticals | , | Gone |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Abbott | Donegal, Ireland | Diagnostics |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| LexaMed | Toledo, OH | Life Science Consulting |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| CombiGene | , | Stopped research Jan 2025 |
| Menarini | Firenze, Italy | Small Molecules |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| Getinge | Rastatt, Germany | Medical Technology |
| Genlantis | , | Acquired by AMSBIO |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| VaxInnate | , | Dissolved Feb 2017 |
| , | Website taken over Feb 2026 | |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| ViroPharma | , | Bought by Shire Jan 2014 |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| CSL Behring | Bradley, IL | Biologics |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| , | Acquired by Kite, Aug 2025 | |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| , | Renamed Mobia Medical, Feb 2026 | |
| Biocode Hycel | , | Website gone |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| Jenken Biosciences | , | Shut down by 2014 |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Navigenics | , | Acquired by Life Technologies 2012 |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Gataca | , | Gone |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| Bayer | Bergkamen, Germany | Small Molecules |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| PluriSelect | El Cajon, CA | Cell Separation |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| Eden Biodesign | , | Bought by Watson |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| Norton Scientific | , | Website Gone, Oct 2014 |
| ChunLab | , | Renamed CJ Bioscience |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| GTX Medical | , | Renamed ONWARD |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| Via Pharmaceuticals | , | Shell Company |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Enterey | Irvine, CA | Life Science Consulting |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| Newormics | , | Renamed vivoVerse, late 2022 |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| , | Acquired by MMS, Feb 2025 | |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Biosion | Nanjing, China | Bispecific Antibody |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Haupt Pharma | , | Merged with Aenova |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| Amaranth Medical | , | Website gone, Apr 2019 |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| Maxwell Biosciences | Austin, TX | Antivirals |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| , | Website down Jan 2026 - May 2026 | |
| Zetra Biologicals | , | Gone |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| MediQuest Therapeutics | , | Gone? |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Endogenx | , | Website Gone Dec 2013 |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Ascend Genomics | , | Shut down |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| Roche | Welwyn, UK | Small Molecules |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Attogene | Austin, TX | Rapid Diagnostics |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| Compugen | San Francisco, CA | Biologics |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| , | Website taken over Feb 2026 | |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| Stago | Franconville, France | Diagnostics |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| Cougar Biotechnology | , | Bought by J&J |
| DecImmune Therapeutics | , | Gone 2017 |
| CoMind | London, UK | Non-invasive brain monitoring system |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| Hope Medicine | Pudong, China | Antibody Therapy |
| Biological Dynamics | , | Shut down Jul 2024 |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Orros Therapeutics | , | gone 2018 |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Zuma Biosciences | , | Company Gone |
| Circadiance | Export, PA | CPAP Mask |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| SuperX | , | Gone |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| Pharmaron | Tianjin, China | R&D Services |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Delpharm | Orléans, France | Contract Manufacturing |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| SYNkinase | , | Shut down |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| RxCelerate | Cambridge, UK | Contract Services |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| , | Website down Nov 2025 - Apr 2026 | |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| PharmaVigilant | , | Gone 2014 |
| , | Acquired by Lonza, Apr 2017 | |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| Veeva Systems | Toronto, ON | Life Science Software |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| |
Allentown, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Biotrofix | , | Gone, Dec 2014 |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Novartis Animal Health | , | Acquired by Lilly |
| Oncofactor | , | Gone 2016 |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| Vascular Biogenics | , | Now VBL Therapeutics |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Brilliant Research | , | Website gone Dec 2018 |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Quakertown, PA | Microionization CDMO | |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| Ambu | Ballerup, Denmark | Medical Devices |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| Regenerative Sciences | , | Took on Regenexx product name |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| Destiny Pharma | Brighton, UK | Antimicrobials |
| Instylla | Bedford, MA | Embolization treatment |
| Synergistix | Sunrise, FL | CRM software |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| , | Website down Jan 2026 - May 2026 | |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| , | Renamed Until Labs, Oct 2025 | |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| Calixar | Lyon, France | Membrane Proteins |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Polytherapeutics | , | Gone Jun 2018 |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| Samsara Sciences | , | Shut Down Mar 2020 |
| Opis Research | Desio, Italy | Clinical Research |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| Kesios Therapeutics | , | Closed down according to investors |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| Microbia-pe | , | Renamed Microbia |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| Compass Biotech | , | Defunct |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| DxTech | , | Seems gone. No info Dec 2015 |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| Chrono Therapeutics | , | Shut Down 2019 |
| Sitka Biopharma | , | Website gone Jan 2022 |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| ADispell | , | Website gone Apr 2018 |
| Revvity | Boston, MA | Diagnostics, Services |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Nucryst | , | Bought by Smith & Nephew |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Nanovelos | , | Subsumed into Nanogroup |
| SoBran | Falls Church, VA | Preclinical Services |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| Maroon Biotech | , | Gone Sep 2010 |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Acureon Pharmaceuticals | , | Closed 2008 |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Rox Medical | , | Gone 2019 |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| Bioenza | , | Website gone Sep 2017 |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| , | Website down Jan 2026 - May 2026 | |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Piper Therapeutics | , | Website gone May 2020 |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| Ergomed | London, UK | Clinical Research |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| UMN Pharma | , | Liquidating Apr 2025 |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| , | Winding down Jan 2026 | |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| MediciNova | La Jolla, CA | Small Molecules |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| Vaxart | South SF, CA | Oral Vaccines |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Acucela | , | folded into Kubota Vision |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| , | Shut down Sep 2025; fka GenoFAB | |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| vTv Therapeutics | High Point, NC | Small molecules |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| CoaguSense | Fremont, CA | Coagulation monitor |
| BioRelix | , | Restructured. Unknown Status. |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Indocruit | , | Gone |
| Beardsworth | , | Bought by TFS International 2013 |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Phoresa | , | Shut down Mar 2018 |
| DP Clinical | Rockville, MD | Clinical Research |
| SYNCROSOME | Marseille, France | Preclinical contract research |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Piramal | Hyderabad, India | CDMO |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| , | Seems inactive Jan 2026 | |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| Chiron | , | Bought by Novartis |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| Ceronco Biosciences | , | Gone 2015? |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| Omnimmune | , | Shell company, trademark abandoned |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| Intellikine | , | Bought by Millennium 2011 |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| , | Shut Down Dec 2024 | |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Bionas Discovery | , | Website gone Jun 2018 |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| Tychan | , | Liquidated early 2022 |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| Extract Technology | Mauston, WI | Containment Equipment |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| , | Website down Jun 2025 - Dec 2025 | |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| Novacta | , | Website Gone, no info |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Ensoma | Boston, MA | in vivo Gene Editing |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| , | Website down Jan 2026 - Apr 2026 | |
| Avrygen | , | Website Gone, execs gone |
| Precise Bio | , | Gone 2023 |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| Acumed | Hillsboro, OR | Medical Implants |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| , | Renamed Edding, Feb 2026 | |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| , | Website down Jan 2026 - May 2026 | |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Xention | , | All programs halted or disposed of by 2016 |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| CellCarta | Montréal, QC | Clinical Research |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ProSci | Poway, CA | Antibodies, etc. |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| Helsinn | Dublin, Ireland | Small Molecules |
| arGEN-X | , | Older name for Argenx |
| Sterling | Barrie, ON | Medical Device Contract Manufacturing & Development |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| TargeGen | , | Bought by Sanofi 2010 |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| LumaBridge | San Antonio, TX | Clinical Research |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| Ankon Technologies | Wuhan, China | Medical Devices |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| Prokarium | London, UK | Oral Vaccines |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Senzime | Uppsala, Sweden | Devices |
| CardioEphEx | , | Shut down Dec 2020 |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| , | Website down Sep 2025 - Jan 2026 | |
| CellASIC | , | Bought by Millipore, May 2012 |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| , | Acquired by Sebia, Sep 2024 | |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| , | Renamed Peritia, Jan 2026 | |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Theranostech | , | Renamed Sandia Biotech |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| , | Acquired by Source BioScience, Apr 2025 | |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| GeneoDx | , | Website gone Oct 2019 |
| VitalMedix | , | Out of Money 2010 |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| , | Acquired by Syner-G BioPharma Group | |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| Octapharma | Springe, Germany | Plasma Products |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Erbe | Tübingen , Germany | Surgical Systems |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Ribopro | Oss, Netherlands | mRNA Services |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Norgine | Hengoed, UK | Specialty Pharma |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Advena | Bromsgrove, UK | Medical Device Regulatory Consulting |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| PathoGene | , | Website taken over, Oct 2017 |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Venebio | Glen Allen, VA | Consultants |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| , | Website down Jan 2026 - May 2026 | |
| Epocal | , | Acquired by Alere, Feb 2013 |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Mendelian | London, UK | Rare Disease Diagnosis |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Erba MDX | , | Website gone Aug 2019 |
| Averion | , | Now Aptiv |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| ABgene | , | Bought by Apogent, Dec 2001 |
| , | Renamed SylamoreBio | |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| Biogenes | Berlin, Germany | Antibodies |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Envision Pharma | , | Merged with UBC |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| Axial3D | Belfast , UK | 3D printing for medical use |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| VieVax | , | Gone Jan 2007 |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| , | Acquired by Versiti, Jul 2023 | |
| Vivacy | Archamps, France | Aesthetic Medicine |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| AnaBioTec | , | Now Anacura |
| Caidya | Shanghai, China | Clinical Research Organization |
| Assay Designs | , | Now Enzo Life Sciences |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| In Cell Art | , | Website taken over Feb 2025 |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| Biocodex | Gentilly, France | Microbiota Treatments |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Diagon | Budapest, Hungary | Hematology Reagents |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| Ganymede | Palo Alto, CA | Lab Automation |
| Kumuda | , | Website gone Mar 2023 |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| Cell Targeting Inc | , | Bought by Biotime |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Evocutis | , | Pivoted to investments |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Siga | New York, NY | Small Molecules |
| , | Website down Jun 2025 - Oct 2025 | |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Molecular Throughput | , | Rebranded as mtibio |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| , | Website taken over Mar 2026 - Apr 2026 | |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Curia | Albuquerque, NM | Contract Research |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Bausch Health | Laval, QC | Small Molecules |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| , | Website hijacked Oct 2025 | |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Nanostream | , | Closed Mar 2008 |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| LeukoSite | , | Acquired by Millennium 1999 |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| EVA Pharma | Giza, Egypt | Branded Generics |
| SomaLogic | Boulder, CO | Blood Analysis |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Serotiny | , | Acquired by J&J, 2023 |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Tigris Pharmaceuticals | , | Now Kirax |
| Abbott | Des Plaines, IL | Diagnostics |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| CGT Global | Folsom, CA | Tissue Sourcing |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Oscor | , | Acquired by Integer, Dec 2021 |
| Tides Medical | Lafayette, LA | Biologics |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| Qynapse | Boston, MA | Imaging Analysis |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Orthologic | , | Now Capstone Therapeutics |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| HistoIndex | Hangzhou, China | Digital Pathology |
| Mepha | Basel, Switzerland | Generics |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| HydroCision | North Billerica, MA | Saline Jet Device |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| , | Acquired by Crypto Group, Jan 2025 | |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Lederle Labs | , | Bought by Wyeth 1994 |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Liposonix | , | Bought by Medicis |
| NovaDel Pharma | , | Business dissolved 2014 |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Cologne, Germany | Surgical Simulation | |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| , | Website down Jul 2025 - Dec 2025 | |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| 206 Ortho | , | Shut down 2021 |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Brain Vision | Morrisville, NC | EEG Systems |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| Pneumolabs | , | Dissolved Sep 2018 |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| HCW Biologics | Miramar, FL | Immunotherapy |
| , | No news 2017 - Apr 2026 | |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| Apharm | , | Now Biofarma Group |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| Octane Biotech | Lucknow, India | Generics |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Elucid | Boston, MA | Arterial Analysis Software |
| , | No news 2020 - Dec 2025 | |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Nesch, LLC | , | Website gone Oct 2018 |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Gravidas Diagnostics | , | preeclampsia POC test |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| BioLegacy Research | San Diego, CA | Contract Research |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| LemnaGene | , | Acquired by Biolex 2005 |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Rezo Therapeutics | San Francisco, CA | |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| , | Acquired by Instem, Jul 2025 | |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| NeuMed | , | Website four years since update, no employees on LI |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| Syantra | Calgary, AB | Breast cancer blood test |
| , | Website down Dec 2025 - Apr 2026 | |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Nucleus Network | Herston, Australia | Clinical Research |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| Vernay | Suzhou, China | Fluid Control Solutions |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Warnex | , | Merged into DIAGNOS Inc |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| Znomics | , | Bankrupt, Shell Company Now |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Lavipharm | Peania, Greece | Small molecules |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Accellacare | Salisbury, NC | Clinical Research |
| Cambridge Pharma | , | Rolled into parent, SMC |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| Raze Therapeutics | , | Closed due to complicated biology |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| , | Website down Sep 2025 - Dec 2025 | |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| MLAB Biosciences | Needham, MA | Biologics |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| Progyny | New York, NY | IVF products |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| , | Website down Jan 2026 - Mar 2026 | |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| CorDx | San Diego, CA | Diagnostics |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| , | Website down Dec 2025 - Mar 2026 | |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Amoytop Biotech | Xiamen, China | Biologics |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Islet Sciences | , | Gone |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Cordis | Miami Lakes, FL | Medical Devices |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Immunovant | Durham, NC | Monoclonal Antibody |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| Pharmaron | Beijing, China | R&D Services |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Heraeus Medical | Dorado, PR | Medical Devices |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| AdipoGenix | , | Gone Jun 2012 |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| , | Acquired by IQVIA | |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| , | Dissolved Jun 2019 | |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| BioVersys | Basel, Switzerland | Drug Discovery |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| Mytos | London, UK | Automated Cell Culture |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| TRPblue | , | Shut down Dec 2023 |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Ascenta Therapeutics | , | Gone |
| Axcend | Lehi, UT | Chromatography Services |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| BBOT | South SF, CA | RAS-targeted small molecules |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| bioMerieux | Cambridge, MA | Diagnostics |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| SDIX | Newark, DE | Diagnostics |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| RQM+ | Monroeville, PA | Regulatory compliance consulting |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| HpVac | , | Renamed Atopia Therapeutics |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Neurologix | , | Bankrupt, Liquidation |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| , | Acquired by Epitype, Oct 2025 | |
| Ottobock | Königsee, Germany | Prosthetics |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| Nephros | South Orange, NJ | Dialysis Devices |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Emulate | Boston, MA | Organs-on-chips |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Lipid Genomics | , | Seems unserious |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| Protein Metrics | Boston, MA | Protein characterization software |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| Vision Medicines | , | Gone 2017 |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| RadioRx | , | Now EpicentRx |
| Proteintech | Wuhan, China | Research Antibodies |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Pharmaron | Beijing, China | R&D Services |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| Pharmathen | Amstelveen, Netherlands | Generics |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| Maplehurst Genetics International | , | Website gone |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| , | Website down Jul 2025 - Dec 2025 | |
| Odyssey Thera | , | Shut down 2014 |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| , | Website down Jul 2025 - Jan 2026 | |
| Santen | Nara, Japan | Ophthalmics |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| ApcinteX | , | Centessa Company |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| CRI | , | Now BiomericsATL |
| , | Renamed Motive Health, Jul 2023 | |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| AblaCor | , | Shut down May 2019 |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| BioVascular | , | 2007 website as of Mar 2019 |
| Linical | Stuart, FL | Clinical Research |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| , | Website down Sep 2025 - Dec 2025 | |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Pharmazz | Greater Noida , India | Small Molecules |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Cytochroma | , | Acquired by Opko Health |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| PX Biosolutions | , | Gone |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Alvea | , | Shut down Oct 2023 |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Kasocio | , | Liquidated, Dec 2019 |
| , | Pivoted to crypto, Apr 2026 | |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| , | Website down Oct 2025 - Feb 2026 | |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Clinical Scientist Group | , | Website gone, employee gone |
| MikrobEX | , | Renamed Rebiotix |
| BioPhyZica | , | Gone 2016 |
| Patronus Biotech | Singapore, | |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Velcura Therapeutics | , | Website Gone |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| , | Acquired by Xoma, Sep 2025 | |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Alliances Catalyst | , | Liquidated |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| WestGene | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| NIOX | Oxford, UK | Asthma management device |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| iThemba Pharmaceuticals | , | No information |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| ApniCure | , | Gone 2017 |
| Celerion | West Conshohocken, PA | Clinical Research |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| Genaera | , | Dissolved |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| PLC Medical Systems | , | Renamed RenalGuard |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| DynoSense | , | Shut down Sep 2022 |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| Nya Cell Therapeutics | , | No info |
| Paranta Biosciences | , | Website gone Dec 2021 |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| NeuroTherapeutics | , | Gone |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| Domainex | Essex, UK | Drug Discovery Services |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| Vernacare | Chorley, UK | Surgical Devices |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| SOLADIS | , | Acquired by Efor, 2021 |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| AM2PAT | , | Trouble with contaminated products, gone |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| AliveDx | Eysins, Switzerland | Diagnostics |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| BostonGene | Waltham, MA | Biomedical Software |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| Ascelegen | , | Closed |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Bio-ops | , | Now SVA |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| Sinusys | , | Shut down 2023 |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Olon USA | Concord, OH | Contract Research |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| , | Website taken over Nov 2025 - Mar 2026 | |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Boston Scientific | Marlborough, MA | Medical Devices |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| DDi | Singapore, Singapore | Clinical Software |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| ClearView | Newton, MA | Strategic Consulting |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| , | Website down Jan 2026 - Mar 2026 | |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Purdue Pharma | Wilson, NC | Small Molecules |
| Carolus Therapeutics | , | Business revoked in CA |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| Coral Drugs | New Delhi, India | APIs |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| Arxspan | , | Renamed SciY |
| Azopharma | , | Bankrupt, Apr 2010 |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Genecure | , | Shut down Sep 2021 |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Corza Medical | Somerset, UK | Surgical Devices |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Biomedica | , | Now part of Oxford Biomedica |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| Clearbridge Biomedics | , | Renamed Biolidics |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| Lifebit | London, UK | Genetic Data Analysis |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| Genialis | Boston, MA | Bioinformatics |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Alumis | South SF, CA | Autoimmune Treatments |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| , | Bought by Veracyte, Mar 2021, $600M | |
| , | Website down Dec 2025 - Apr 2026 | |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Knopp Biosciences | , | |
| DLK Medical Technologies | Dallas, TX | OTC |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Suir Pharma | , | Bankrupt, May 2016 |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Cedilla Therapeutics | , | Shut down May 2023 |
| Excelimmune | , | Closed Jul 2016 |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Rheos Medicines | , | Shut down Dec 2022 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Novometrics | , | Dissolved Dec 2019 |
| Nano Science | , | Acquired by EAG, 2006 |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| Sytera | , | Merged with Sirion Aug 2006 |
| , | Seems to be News website, Jan 2026 | |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| , | Assets Acquired by Klotho, Sep 2025 | |
| MediLink Therapeutics | Suzhou, China | ADC |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| Kereos | , | Seems gone |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| Abbott | Longford, Ireland | Diagnostics |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| MSN Labs | Hyderabad, India | Generics |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Tripos | , | Bought by Certara |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Accugent Laboratories | , | Website gone Sep 2017 |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| EVerZom | Paris, France | Exosome Therapeutics |
| Allelix | , | Merged with NPS |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| ParinGenix | , | Gone, 2012? |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| ImmuRx | , | Gone, not sure what happened |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Valsphere | , | Website gone Nov 2019 |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| Ezose Sciences | , | Rebranded as S-bio |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| , | Shut down June 2024 | |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| ARCBio | , | Shut down 2014 |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| , | No news 2020 - Apr 2026 | |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| Gene Express Inc | , | bankrupt? |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| Confer Health | , | Shut down 2021 |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| OP2 Drugs | , | Website gone Jan 2020 |
| Nanosens | , | Merged into Cardea Oct 2019 |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| Cardeas Pharma | , | Gone, 2017 |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| ERBC | Baugy, France | Non clinical CRO |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Mentrik Biotech | , | Gone |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| Compugen | Holon, Israel | Biologics |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| StemPar Sciences | , | Website disappeared, no news |
| CD Genomics | Shirley, NY | Genomics Services |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| BIND Biosciences | , | Now BIND Therapeutics |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| Apini Therapeutics | , | |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| PTM BioLabs | , | Renamed PTM BIO |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| Alxerion Biotech | , | Gone May 2021 |
| Alnis BioSciences | , | No info |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Curia | Rensselaer, NY | Contract Research, Development, Manufacturing |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| 3T Biosciences | South SF, CA | TCR Therapies |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Ambion | , | Bought by Applied Biosystems 2006 |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Ceptyr | , | Out of business 2012 |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| Satya | Hyderabad, India | Small Molecule |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| JustRight Surgical | , | Renamed Bolder Surgical |
| , | Website taken over, Feb 2026 | |
| Salvat | Madrid, Spain | Small Molecules |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Gallus | , | Bought by Patheon, Aug 2014 |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Excelsyn | , | Bought by AMRI |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Ergomed | Zagreb, Croatia | Clinical Research |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| Par Health | St. Louis, MO | Generics |
| Novahep | , | Website down, Oct-Dec 2017 |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| , | ||
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| , | Pivoted to defense contracting, Jan 2026 | |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Inflammix | , | Renamed AnchorBio Solutions |
| Akesobio | Zhongshan, China | Antibody Therapies |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| Vernacare | Newtown, UK | Surgical Devices |
| , | Part of Genesis | |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| Allievex | , | Shut down Feb 2025 |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Innomab | , | Gone 2017 |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| Pharma Medica | Toronto, ON | Clinical Services |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| Hematogenix | Tinley Park, IL | Pharma Services |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| NascaCell | , | German Aptamer company, not sure of fate |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| , | Website down Aug 2025 - Jan 2026 | |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Drugabilis | Villejust, France | Druggability Services |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| K2M | , | Acquired by Stryker, Nov 2018 |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| Ansaris | , | Gone |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Novitium Pharma | East Windsor, NJ | Generics |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| , | Website down Dec 2025 - Apr 2026 | |
| Zyagen | San Diego, CA | Life Science Reagents |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| , | ||
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Omnia Biologics | , | Website gone Sep 2017 |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Alkermes | Wilmington, OH | Small Molecules |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| Roche | Laval, QC | Diagnostics |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Rad AI | San Francisco, CA | Radiology Software |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| AB Sciex | , | Renamed Sciex |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| MSD | Brinny, Ireland | Small Molecules |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| AbRegen | , | Website gone, Mar 2019 |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| Intica Biomedical | , | Bankrupt 2014 |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| AstraZeneca | Boston, MA | Biologics |
| Acologix | , | Closed Aug 2011 |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| ArKal Medical | , | Gone 2012 |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| Cellcion | , | Website gone, company going inactive |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Synosia Therapeutics | , | Acquired by Biotie |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| Typharm | Norwich, UK | Generics |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| BioWa | , | Part of Kyowa Kirin Group |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | Website down Dec 2025 - Apr 2026 | |
| InterGenetics | , | Assets auctioned |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Menarini | Dresden, Germany | Small Molecules |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Protalex | , | Failed 2018, shell |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| Obecure | , | Inactive, no info |
| Coldstream Laboratories | , | Bought by Piramal |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| Scion Medical Technologies | , | Gone 2016 |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| TaliaPharm | , | Website gone, Jan 2018 |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| Vanadis Laboratories | , | Gone 2018 |
| Inspirata | North York, ON | Cancer Insights |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| Protein Polymer Technologies | , | Basically Gone |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| PhotoThera | , | Ceased operations Dec 2012 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| EQL Pharma | Lund, Sweden | Generics |
| Alcon | Irvine, CA | Eye-Care Products |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| Supeira | , | Website gone Mar 2023 |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Ahmedabad, India | Clinical Trials | |
| Auris Medical | , | Renamed Altamira Therapeutics |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| Epixis | , | Acquired by VBI Vaccines |
| Alife | San Francisco, CA | AI-powered IVF |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| La Jolla Biologics | , | Website gone Nov 2014 |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| Cytiva | Burnaby, BC | Cell Culture Products |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Eccogene | Shanghai, China | Small Molecules |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| Infinity Bio | Baltimore, MD | Reactome Services |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Sage Science | Beverly, MA | DNA Fractionation |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| Xyntek | , | Segment of non-life science business |
| Synentec | Elmshorn, Germany | Cell Imaging |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Ergomed | Prague, Czech Republic | Clinical Research |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| , | ||
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Getinge | Vendôme, France | Medical Technology |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| Augmenta Biologicals | , | Website Gone May 2014 |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| EuBiologics | Seoul, Korea | Vaccines |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| , | Liquidating, Mar 2025 | |
| NeuTec Pharma | , | Shut down 2010 |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Ingenetix | Wien, Austria | PCR Products |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| NovoMedix | San Diego, CA | Small molecules |
| Epigenetix | , | No annual report filed 2013-2019 |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| LinaTech | Suzhou, China | Cancer treatment device |
| Meta-Iq | , | Website gone Jun 2020 |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Salgomed | , | Shut down Apr 2022 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| Kate Therapeutics | , | |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| Endologix | Irvine, CA | Medical Devices |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| Mediso | Budapest, Hungary | Medical Imaging |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| , | Website down Dec 2025 - Apr 2026 | |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| , | Renamed Helyx Industries | |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| LifeMax | , | Part of AmMax |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| Resilience | Alameda, CA | Biomanufacturing |
| PolyMedix | , | Bankrupt Apr 2013 |
| Vedere Bio II | , | Shut down Mar 2023 |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Bakhu Pharma | , | Bankrupt, location sold |
| Silenseed | , | Renamed Silexion |
| CYTOO Cell Architects | , | |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Nephrion | , | Closed 2006? |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Mousera | , | Renamed Vium |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Apobiologix | Toronto, ON | Biosimilars |
| CereSpir | , | No news 2020 - Nov 2024 |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| OraPharma | , | Owned by Valeant |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| VentriFlo | Pelham, NH | Blood Pumping System |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| Abcam | Waltham, MA | Antibodies |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| Recensa Therapeutics | , | Only employee gone 2018 |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| Abbott | Alameda, CA | Diabetes Care |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Nexus Spine | Draper, UT | Spinal Implants |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| PlaSalus | , | Amateurish looking |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| OncoCell MDx | , | Renamed Immunis.AI |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Parsolex | , | |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| Meissner | Castlebar, Ireland | Lab Systems |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| Altasciences | Montréal, QC | Contract Research |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| Ergomed | Raleigh, NC | Clinical Research |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| , | business filings late Oct 2023 - Oct 2025 | |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| BIOS Health | Cambridge, UK | Neural interface platform |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| BHR Pharma | , | Subsidiary of Besins |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| StaphOff Biotech | , | Shut down 2017 |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| Nexgenia | , | Gone Dec 2019 |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Prescos | , | Shut down Feb 2014 |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Madera Biosciences | , | Shut down Aug 2020 |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| , | Website down Jul 2025 - Dec 2025 | |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| , | Acquired by Glaukos, Aug 2025 | |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Biobase | , | Bought by Qiagen, May 2014 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Logan Medical Devices | , | Gone? |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Anavex Life Sciences | New York, NY | Small Molecules |
| Promaxo | Oakland, CA | Small form MRI |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| Eargo | San Jose, CA | Hearing Aids |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| Aresus Pharma | , | Seems folded in to Dermago |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| Syneos Health | Newtown, PA | Clinical Development |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| Allenex | , | Bought by CareDx, Apri 2016 |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| Prolexys Pharmaceuticals | , | Website Gone |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| , | Website down Jul 2025 - Dec 2025 | |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Genitope | , | Wound Down |
| Cytopeia | , | Acquired by BD, May 2008 |
| Animas | , | Shut down, Oct 2017 |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Kura Oncology | San Diego, CA | Small Molecules |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Pharma Medica | Mississauga, ON | Clinical Services |
| , | Renamed Indero | |
| Delpharm | Milan, Italy | Contract Manufacturing |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| , | ||
| Occam Design | Louisville, SS | Medical Device Development |
| , | Merged with ABX-CRO | |
| Duramed | , | Acquired by Barr Labs 2001 |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| Vernacare | Bolton, UK | Surgical Devices |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Turing Medical | St. Louis, MO | Neuromodulation |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| , | Website down Nov 2025 - Apr 2026 | |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Evalve | , | Owned by Abbot Vascular |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| Heraeus Medical | Kolkata, India | Medical Devices |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| , | Renamed FocalOne, Feb 2026 | |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| , | Website down Oct 2025 - Feb 2026 | |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| TruGenomix | , | Renamed Polaris Genomics |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| |
Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| ProtAffin | , | Winding Down |
| , | Renamed Revr Jan 2026 | |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Xact Medical | , | Website down Mar 2024 |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| M3 Wake Research | Encino, CA | Clinical Research |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| Balance Therapeutics | , | Gone late 2020 |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| SutroVax | , | Renamed VaxCyte |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Borean Pharma | , | Gone |
| ResMed | San Diego, CA | Medical Devices |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| VALOS | Genova, Italy | Clinical Statistics |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| Iquity Labs | , | Merged into Decode Health |
| Neuro Bio | Oxford, UK | T14 Blocker |
| KVK Tech | Newtown, PA | Generics |
| Adlyfe | , | Gone, no info |
| Quanticate | Raleigh, NC | Clinical Research |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| Nascent Biologics | , | Changed to Nascent Biotech |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| ConquerX | , | Dissolved Jun 2021 |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| Microsure | Son, Netherlands | Surgical Robots |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Cytera CellWorks | , | Renamed Mytos |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| GigaGen | San Carlos, CA | Immune therapeutics |
| iBio | San Diego, CA | Antibody Therapies |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| , | Acquired by hVIVO, Dec 2019 | |
| Amorsa Therapeutics | , | Acquired, 2022 |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Immerge BioTherapeutics | , | Founded 2000 |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| , | Website down May 2025 - Dec 2025 | |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| Lombard Medical | Didcot, UK | Medical Devices |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Abbott | Sylmar, CA | Device Manufacturing |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| InteguRx | , | Website taken over, Dec 2023 |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Assurance Scientific Laboratories | Austin, TX | Molecular Technologies |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Turku Bioscience | Turku, Finland | Research Services |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| BioMS Medical | , | Gone? |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| SE3D | , | Renamed Seed Therapeutics |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| , | Winding down Apr 2026 | |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Venta Medical | , | Gone, Apr 2017 |
| SilaGene | , | Gone |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| Spyryx Biosciences | , | Shut down 2019 |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| Angioslide | , | Gone, Oct 2009 |
| Best Vascular | , | Now Best Vascular Novoste |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Oncogen | , | Acquired by BMS, 1986 |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| AltaRex | , | Gone |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Amstem | , | SEC problems |
| Validation Associates | Herndon, VA | Validation Consulting |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Halloran Consulting Group | Boston, MA | Consulting |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Stada | Bad Vilbel, Germany | Generics |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| EcoSurg | , | Shut Down May 2017 |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| PRACS Institute | , | Bankrupt 2013 |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Grifols | Clayton, NC | Biologics |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| , | Acquired by Instem, Jul 2025 | |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| Diagast | Loos, France | Transfusion Reagents |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| RenovoRx | Mountain View, CA | Catheters |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Axplora | Pompey, France | CDMO Services |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Aranscia | Houston, TX | Diagnostic Software |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| Curia | Springfield, MO | Contract Development, Manufacturing |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| , | Website down Aug 2025 - Jan 2026 | |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| QuantRx Biomedical | , | Shell company |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| BioArctic | Stockholm, Sweden | CNS treatments |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Derma-Cell Research | , | Website gone Nov 2019 |
| Inventa Biosciences | , | Not Active |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| Promedior | , | Acquired by Roche, Feb 2020 |
| Accelsiors | Budapest, Hungary | Clinical Research |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| , | Website down Sep 2025 - Feb 2026 | |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| NanoVector | , | Gone 2019 |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| KynderMed | , | Renamed Prena |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Jerini | , | Acquired by Shire, 2008 |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| TumorGen | San Diego, CA | Cancer Treatments |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| Tangent Medical Systems | , | Closed |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| , | Website down Nov 2025 - Apr 2026 | |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| BG medicine | , | Gone 2019 |
| Deimos Biosciences | , | |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Integrated Genomics | , | Changed to Igenbio |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| Stago | Maastricht, Netherlands | Diagnostics |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| , | Acquired by Millipore, Dec 2010 | |
| Keenova | Hazelwood, MO | Small Molecules |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| Ekteino | , | Closed, Dec 2016 |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| KeraCure | , | Gone 2014 |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| , | Gone before Dec 2025 | |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| LyoTechnica | , | Gone |
| EyeTel Imaging | , | Gone Jul 2015 |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Fusion Biopharma | , | Presumed gone |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| NeurAegis | , | Seems gone, Sep 2022 |
| Empatica | Milan, Italy | Seizure Detection |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Formex | , | Merged into BioDuro, Nov 2015 |
| |
Macungie, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| Formation Biologics | , | Rebranded as Forbius |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Oncodesign Services | Dijon, France | Preclinical services |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Mitos Pharmaceuticals | , | Website Gone |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Velos | , | Acquired by WCG, Mar 2018 |
| Develco Pharma | Schopfheim, Germany | Generics |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| Medistem | , | Bought by Intrexon Dec 2013 |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Octapharma | Lingolsheim, France | Plasma Products |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| , | Acquired by Embecta, Mar 2026 | |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Elegen | San Carlos, CA | DNA writing |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| Avexa | , | Renamed Novita Healthcare |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| Nostrum Laboratories | Kansas City, MO | Generics |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Skylit Medical | , | Renamed Clarify medical |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| , | Renamed PKx Bio, 2026 | |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Sebia | Lisses, France | Electrophoresis |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| Curadigm | , | folded into Nanobiotix |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Cellworks | South SF, CA | Biosimulations |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| bespark*bio | Vienna, Austria | Consulting |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Angex Pharmaceuticals | , | Gone 2018 |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Alkermes | Waltham, MA | Small Molecules |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| Integer | Salem, VA | Medical & Surgical Devices |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| V-gene | , | Website gone, Aug 2017 |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| SpinalMotion | , | Website gone, 11-30-14 |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| EmpathBio | , | |
| , | Website taken over, Nov 2025 | |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| inDNA Research Labs | , | Shut down 2015 |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| Ebewe Pharma | , | Now Sandoz |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Trudell Medical | London, ON | Inhalation Devices |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Applied Integrin Sciences | , | Gone |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Pharmathen | Marousi, Greece | Generics |
| Simondr | , | Website gone, President has new job |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| AstraZeneca | Baar, Switzerland | Biologics |
| , | Website down Jun 2025 - Dec 2025 | |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Rhythm Health | , | Renamed Motus Therapeutics |
| Otsuka | Tokushima, Japan | Small Molecules |
| Nova Biomedical | Norwood, MA | Lab instruments |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| , | Website down Jul 2025 - Dec 2025 | |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| , | Website down May 2025 - Oct 2025 | |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| GSK | Hamilton, MT | Vaccine additive |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Mologen | , | Liquidating, May 2020 |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| SenzaGen | Lund, Sweden | Genomic Assays |
| CreaGen | Woburn, MA | Drug Discovery Services |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| Taxolog | , | Website gone, Nov 2015 |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| , | Gone Mar 2024 | |
| Bioclinica | , | Merged with ERT, 2021 |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| Novotech | Seoul, Korea | Clinical Research |
| Arzeda | Seattle, WA | Computation protein design |
| BZL Biologics | , | Gone 2003 |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| Allogene Therapeutics | South SF, CA | CAR-T |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Aadigen | , | Renamed Aanastra |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| Abbott | Altavista, VA | Nutrition |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| MicroPort | Arlington, TN | Medical Devices |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| MabPrex | , | Out of business, 2016 |
| AtCor Medical | , | Now part of CardieX |
| Deepcell | Menlo Park, CA | Genetic Tests |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| Validant | , | Renamed Eliquent Life Sciences |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| , | Website taken over Feb 2026 | |
| Diamed | , | Bought by Bio-rad |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| Cerba Research | Ghent, Belgium | Lab Testing |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Profluent | Emeryville, CA | AI Protein Creation |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Kentucky Bioprocessing | , | Now Kbio |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| CureBiotech | , | Presumed gone |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| , | ||
| Synergistix Biotech | , | Dissolved Dec 2003 |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Quanticate | Hitchin, UK | Clinical Research |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| Ergomed | Frankfurt, Germany | Clinical Research |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| Shionogi | Florham Park, NJ | Small Molecules |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Cancervax | , | Acquired by Micromet, May 2006 |
| Qool Therapeutics | , | Gone Jan 2021 |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Phenomyx | , | Gone Jun 2019 |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| AL-S Pharma AG | , | New Dec 2016, no site Aug 2018 |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| , | Shut down Jan 2026 | |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| PRI Research | , | Renamed Wake Clinical |
| RecomGenex | , | Renamed TargetEx Biosciences |
| VAXX | , | Not sure what happened to them |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| , | Website down Oct 2025 - Jan 2026 | |
| Tyrian Diagnostics | , | Gone 2012 |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| , | Website down Sep 2025 - Feb 2026 | |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Neurokos | , | Gone. No info |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| SNBL | , | Acquired by Altasciences |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| VB Spine | Allendale, NJ | Spinal Implants |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| Alkermes | Dublin, Ireland | Small Molecules |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Predictive Therapeutics | , | Renamed NeoTX |
| , | No info 2019 - Mar 2026 | |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| , | No news 2022 - Mar 2026 | |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Getinge | Ankara, Turkey | Medical Technology |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Getinge | Antalya, Turkey | Medical Technology |
| , | Renamed ExGen Dx, Jul 2025 | |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| BEAT BioTherapeutics | , | Closed 2017 |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| PreventAGE Health Care | , | fka Journey Biosciences |
| Veryan Medical | Horsham, UK | Helical Stent |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| , | Renamed ElisiGen, Dec 2025 | |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Akesis LLC | , | Bankrupt 2015 |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| Figure8 Surgical | , | Surrendered business in CA |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Conkwest | , | Website gone Dec 2015 |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| HackScience | , | Renamed Cytera, Nov 2018 |
| Tolmar | Fort Collins, CO | Small Molecules |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Cristers | Suresnes, France | Generics |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| , | Now PamDx, May 2026 | |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Ipsen | Dublin, Ireland | Small Molecules |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| , | Website down Oct 2025 - Feb 2026 | |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| ProtonDx | London, UK | Diagnostics |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| ExcelseBio | , | Part of IntegrityBio |
| Spherics | , | Bankrupt |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| OpenClinica | Needham, MA | Clinical Study Software |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Vivifi Life Sciences | Bangalore, India | Generics |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Biowarn | , | Gone |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Terpenoid Therapeutics | , | Gone |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| PharmaGap | , | Shut down 2013 |
| , | Renamed Alethio Therapeutics | |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| Roche | Basel, Switzerland | Diagnostics |
| Surepharm | , | Liquidating, Apr 2025 |
| Prime Biologics | , | Seems gone 2019 |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| AngioCure | , | Employees all gone, Nov 2017 |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| Loop Therapeutics | , | Shut down Jan 2021 |
| Batu Biologics | , | Gone 2019? |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| , | Renamed Helus Pharma, Jan 2026 | |
| , | Acquired by Eclipsebio, Jan 2026 | |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| Ampac Analytical | , | part of SK pharmteco |
| Mankind Pharma | New Delhi, India | OTC? |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| GeNO | , | Renamed Vero Biotech, 2018 |
| , | Website down Aug 2025 - Jan 2026 | |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| Tensys Medical | , | Website gone Sep 2017 |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| Navinta | Ewing, NJ | Generics |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Gameto | New York, NY | Female Fertility Extension |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| Tapestry Pharmaceuticals | , | Gone |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| , | Website down Oct 2025 - Feb 2026 | |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| British Biotech | , | Merged into Vernalis 2003 |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Novotech | Bangalore, India | Clinical Research |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| Ergomed | Cologne, Germany | Clinical Research |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| , | ||
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Endotis Pharma | , | Founded in 2003. No info |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| , | Renamed Aspen Neuroscience | |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Moon Surgical | Paris, France | Robotic Surgery System |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Medallion Therapeutics | , | Shut down 2018 |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Angiosyn | , | Acquired by Pfizer 2005 |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| Luvak Lab | , | Dissolved 2013 |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| NKT Therapeutics | , | Shut down May 2021 |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Liverpool, UK | Clinical Research | |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Dalex Biotech | , | Gone |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| Five Star Products | , | Liquidated |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| Xenova | , | Acquired by Celtic Pharma |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| Dropshot Therapeutics | , | |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| Medrobotics | , | Bankrupt Jun 2022 |
| , | Part of Greenpharma | |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Abnovo | , | Gone |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Studylog | South SF, CA | Animal Study Workflow Software |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| , | No news 2019 - Oct 2025 | |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| Empatica | Cambridge, MA | Seizure Detection |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Accellacare | Ames, IA | Clinical Research |
| Sanofi | Frankfurt, Germany | Small Molecules |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Ablacon | , | Shut down Mar 2024 |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| Ameridose | , | Shut Down 2012 |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| , | Website down Aug 2025 - Jan 2026 | |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| Aspira Scientific | , | Gone Nov 2015 |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Refined Diagnostics | Münster, Germany | Lasers |
| MSD | Dublin, Ireland | Women's Health Products |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Baxter | Deerfield, IL | Medication Delivery |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Cue Biopharma | Boston, MA | Immunotherapy |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| 1CellBio | , | Gone Jun 2019 |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Esper Therapeutics | , | Shut down 2016 |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| AB ANALITICA | Padua, Italy | Sequencing products |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| AllerMAbs | , | Website gone Oct 2022 |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Apnex Medical | , | Shut down, Aug 2013 |
| Immunovaccine | , | Rebranded IMV, 2018 |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| Noucor Health | Barcelona, Spain | Small Molecules |
| Apollomics | Xiaoshan, China | Cancer medicines |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Evidera | , | Acquired by PPD, 2016 |
| Intellimedix | , | Company founder/employee all moved on |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Abpro | Woburn, MA | Antibodies |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| 89bio | San Francisco, CA | Liver Treatments |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| , | Website down Sep 2025 - Feb 2026 | |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| CMD Bioscience | , | Closed, 2015 |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| Coley Pharma | , | Acquired by Pfizer |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| Getinge | Växjö, Sweden | Medical Technology |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Transmed Oncology | , | Gone? |
| , | Renamed Carvolix, Feb 2026 | |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Pangenetics | , | Bought by Abbott |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Integra LifeSciences | Andover, UK | Medical Devices |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Alvogen | Morristown, NJ | Generics, OTCs |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Niagara Biosciences | , | No info, Aug 2022 |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| Provasculon | , | Website Gone, Apr 2014 |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| Metris Therapeutics | , | Presumed Gone |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| CMP Pharma | Farmville, NC | Small Molecules |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| Sequel Pharmaceuticals | , | Gone |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Novita Healthcare | , | Renamed TALi Digital |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Lupin | Baltimore, MD | Generics |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Agendia | Irvine, CA | Breast Cancer Assay |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Develco Pharma | Pratteln, Switzerland | Generics |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| DDL | Eden Prairie, MN | Device Testing |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Acculysis | , | Website gone, sole employee with Agilent now |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Human Genome Sciences | , | Bought by GSK |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| AccelaPure | , | Bankrupt 2007 |
| IMMY | Norman, OK | Fungal Diagnostics |
| Novotech | Sydney, Australia | Clinical Research |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| AmProtein | , | Presumed Gone |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Panther Orthopedics | , | Shut down Dec 2022 |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| , | CEO left 2020, still on website Dec 2025 | |
| , | Acquired by Sartorius, Apr 2025 | |
| Antabio | Labège, France | Antibacterial drugs |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| PsiOxus Therapeutics | , | |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| , | Website down Aug 2025 - Jan 2026 | |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Tarsa Therapeutics | , | Product rights acquired |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| Guardion Health Sciences | , | Shut down |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Altiris Therapeutics | , | Presumed Gone |
| Epigenos Biosciences | , | |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| Curadev | Noida, India | Immuno-oncology |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Talima Therapeutics | , | Closed 2011 |
| , | Renamed NeuraNova, Jan 2026 | |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Saghmos Therapeutics | , | |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| Delpharm | Quetigny, France | Contract Manufacturing |
| CG Therapeutics | , | Dissolved Jul 2013 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| VIVUS | Campbell, CA | Small Molecules |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Exelixis | Alameda, CA | Small Molecules |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Kalypsys | , | Gone |
| , | Website down Oct 2025 - Feb 2026 | |
| PromoCell | Heidelberg, Germany | Cellular Products |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Qynapse | Paris, France | Imaging Analysis |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| |
Bethlehem, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Grove Instruments | , | Shut Down June 2017 |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| Medicure | Holetown, Barbados | Small Molecule |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| , | Renamed Ensera, Oct 2025 | |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| deCODE Biostructures | , | Now Emerald Biostructures |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Lunit | Seoul, Korea | AI Image Analysis |
| Abbott | Clonmel, Ireland | Stents |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| Alte Biosciences | , | Gone, Apr 2016? |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Balboa Biosciences | , | Gone 2010 |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| Micropore Technologies | Hyderabad, India | Membrane-Based Process Equipment |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| DC Biosciences | , | Shut down Jul 2023 |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Pristine Bioproduction | , | Not a going concern |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| Cell Matrix | , | Acquired by Cancervax |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| PeriCor Therapeutics | , | Website Gone |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Modern Biosciences | , | Renamed Istisso |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| Senseonics | Germantown, MD | Medical Devices |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| Molsoft | San Diego, CA | Drug Design Software |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| American Regent | Shirley, NY | Generics |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| MitoStem | , | Seems gone |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Heritage Pharmaceuticals | , | Part of Emcure |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| GSL Biotech | , | Acquired by Dotmatics |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Angiosonics | , | Shut down 2002 |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Dexcom | San Diego, CA | Glucose Monitors |
| , | Website down Nov 2025 - Apr 2026 | |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Cytecs | Münster, Germany | Cell Analysis |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| Itero Biopharmaceuticals | , | Website Gone |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| Labopharm | , | Bought by Paladin 2011 |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| Tecomet | Wilmington, MA | Implant Components |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| SteriTech | Surrey, UK | Process Equipment |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| KAI Research | , | Acquired by Navitas Life Sciences |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Ozgene | Bentley, Australia | Genetically modified mice |
| Metronomia | Munich, Germany | Consulting & Data Management |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| Antyra | , | Gone |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| , | Website down Dec 2025 - Apr 2026 | |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| Orthogonal LLC | Chicago, IL | Medical device software |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| VGX Pharmaceuticals | , | Merged with Inovio |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Trimeris | , | Merged with Synageva |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| SK Biotek | , | part of SK pharmteco |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Bastion Therapeutics | , | Shut down |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| Calypte Biomedical | , | Gone |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Scinomix | Earth City, MO | Lab Automation Products |
| Amivas | Waterford, Ireland | Antimalarial |
| Hemaquest | , | Gone by 2017, No info |
| Apalexo Biotechnologie | , | No info, probably gone |
| Healionics | Seattle, WA | Biomaterials for devices |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| Instil Bio | Dallas, TX | Cell Therapy |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| , | Website down Sep 2025 - Dec 2025 | |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| Pathnostics | Irvine, CA | Diagnostics |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| , | ||
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Virscio | New Haven, CT | Contract Research & Consulting |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Marical | , | Website Gone |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Altravax | , | Shut down 2016 |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| Berlex | , | Now Bayer |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| IntelligentMDx | , | Shut down Feb 2015 |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Advangen | , | Acquired by Cellmid, May 2013 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| , | Shut down Jan 2025 | |
| Stago | Tianjin, China | Diagnostics |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Lusochimica | , | Owned by Menarini |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Ataia Medical | , | Website taken over Jan 2024 |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| Fabric Genomics | Oakland, CA | Computational genomics |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| MDQuest | , | Website Down Feb 2025 |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| Coordination Therapeutics | , | Not Active |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Biomendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Beta-Pro | , | Now Triangle Research Labs |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| Aceto | , | Renamed Actylis, Sep 2022 |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| Boston Scientific | Valencia, CA | Medical Devices |
| Creative Bioinformatics Consultants | , | Gone |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Hemay Pharmaceutical | Tianjin, China | |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Anthra Pharmaceutical | , | Gone |
| Medpace | Cincinnati, OH | Clinical Research |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| LivaNova | London, UK | Nerve stimulation therapy |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| , | Website down Oct 2025 - Feb 2026 | |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| Quiescence Technologies | , | Website Gone |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Synostics | , | Gone 2014 |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Excelya | Boulogne, France | Clinical Research |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| Diassess | , | Renamed Lucira Health |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Scios | , | Bought by JnJ, Feb 2003 |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| BioCrea | , | Website Gone, Feb 2018 |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| Bionode | , | Shut down Mar 2024 |
| Accellacare | Downers Grove, IL | Clinical Research |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| NovoLipid | , | Website Gone |
| , | Website down Nov 2025 - Mar 2026 | |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| Accumed Systems | , | Dated website, cant find any employees |
| Biocoat | Horsham, PA | Medical Device Coatings |
| NanoBio Systems | , | Shut Down Jun 2022 |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Gangagen | Bangalore , India | Ectolysins |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Tequesta BioScience | , | Defunct |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| , | Website down Jan 2026 - May 2026 | |
| , | Acquire by Savillex, Nov 2024 | |
| , | Website down Oct 2025 - Dec 2025 | |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| Alkem Labs | Mumbai, India | Generics |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| Catalina Pharma | , | No info 2017-2022 |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Whole Biome | , | Renamed Pendulum Biosciences |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| Qrativ | , | Folded into nFerence |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| , | Renamed Novakand Pharma, Sep 2025 | |
| Zai Lab | Cambridge, MA | Small Molecules |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Hovione | Mumbai, India | Contract Manufacturing |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Traversa Therapeutics | , | Bankrupt |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| VM Discovery | , | 20 yr old company with no info on website |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| Attenuon | , | Now Tactic |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Riverain Technologies | Miamisburg, OH | Imaging |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| Ergomed | Mumbai, India | Clinical Research |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| Stada | Bad Vilbel, Germany | Generics |
| Curia | Tonneins, France | Contract Development, Manufacturing |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| Divergence | , | Bought by Monsanto |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| Bellus Medical | , | Renamed Crown Aesthetics |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Perlara PBC | , | Shut down Feb 2019 |
| Pharmexon | Prague, Czech Republic | Consulting |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| Resilience | East Norriton, PA | Biomanufacturing |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| ZipBio | Seattle, WA | Compact Proteins |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Soletics | , | Website gone Jun 2021 |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| Modular Medical | San Diego, CA | Insulin Pump |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Chanelle Pharma | Amman, Jordan | Generics |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| DNAe | London, UK | Next-gen Sequencing |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| Pharmos | , | Gone |
| Curia | Camarillo, CA | Contract Development, Manufacturing |
| Northfield Laboratories | , | Bankrupt 2009 |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| Accium BioSciences | , | Shut down Oct 2024 |
| Vectura | , | |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| Grifols | Durham, NC | Biologics |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| |
Conshohocken, PA | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Bioventus | Durham, NC | Orthobiologics |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Advancells | Noida, India | Stem Cell Treatments |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Alltrna | Cambridge, MA | tRNA therapies |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| , | Website down Jun 2025 - Dec 2025 | |
| Amherst Pharmaceuticals | , | Gone 2019 |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Biovail | , | Merged with Valeant |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| Nycomed | , | Acquired by Takeda 2011 |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Monroe Research | Monroe, NC | Clinical Trials |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Biocorp | Issoire, France | Medical Devices |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Talee Bio | , | Renamed Spirovant Sciences |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| Anazen Diagnostics | , | Part of Cardiox |
| Celerion | Lincoln, NE | Clinical Research |
| , | Website down Jul 2025 - Dec 2025 | |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| PDL BioPharma | , | Shut down early 2021 |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| Barc Lab | , | Renamed Cerba Research |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| FFE Therapeutics | , | Shut down Dec 2013 |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| , | Shut down Jan 2024 | |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| , | Website down Oct 2025 - Feb 2026 | |
| LakeShore Biopharma | Beijing, China | Vaccines |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| Tecomet | Kenosha, WI | Implant Components |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| Copley Scientific | Nottingham, UK | Test equipment |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Redpoint Bio | , | Inactive |
| NeuroSearch | , | Wound down 2012 |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Abgenix | , | Bought by Amgen 2006 |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| Getinge | Orléans, France | Medical Technology |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| Clarapath | Hawthorne, NY | Pathology Device |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| , | Website down Nov 2025 - Apr 2026 | |
| Getinge | Solna, Sweden | Medical Technology |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| TandemAI | New York, NY | AI to democratize the drug development process |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| , | Founder, Principal gone Sep 2024 | |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Sonosine | Kidlington, UK | Medical Imaging |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| CareDx | Brisbane, CA | Diagnostics |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| , | Renamed Algernon Health, Oct 2025 | |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Micrologix Biotech | , | Renamed Migenix |
| Collgard Biopharmaceuticals | , | Gone |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| CyteGen | , | 2015 founded, website never active |
| , | Website down Dec 2025 - Apr 2026 | |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Stopped work Aug 2025, IP company | |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| SulfaGENIX | , | Website gone, Jan 2019 |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| ProPharma Group | Fort Washington, PA | Consulting |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| , | Renamed THX Pharma, Sep 2025 | |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| Gilson | Middleton, WI | Lab Supplies |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Alfama | , | Merged into Proterris, May 2017 |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| ABL | Lyon, France | Viral Vector CDMO |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| , | Website down Jul 2025 - Dec 2025 | |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Solventum | St. Paul, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| , | Website down Sep 2025 - Dec 2025 | |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| EMD Serono | Boston, MA | Biologics |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Roowin | Riom, France | Chemical Synthesis |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| , | Seems gone, Feb 2026 | |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| , | Website down Jul 2025 - Dec 2025 | |
| Evozyne | Chicago, IL | Protein Design Platform |
| Lupin | Mumbai, India | Generics |
| Piramal | Grangemouth, UK | CDMO |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| ProCrysta Biologix | , | Shut down 2018 |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| BridGE Genomics | , | Gone 2022 |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Oak BioSciences | , | Shut down Nov 2024 |
| Zephyr AI | McLean, VA | AI Data Analysis |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Amniox Medical | , | Folded into BioTissue |
| , | part of ElevateBio; fka LifeEDIT | |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| Streck | La Vista, NE | QC & Diagnostic Products |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| FIT Biotech | , | Bankrupt Feb 2019 |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| iCareDx | , | Renamed AcuamarkDx |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Alcon | Houston, TX | Eye-Care Products |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| Keenova | Malvern, PA | Small Molecules |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| Stada | Vršac, Serbia | Generics |
| Topivert | , | Liquidating Jan 2021 |
| Affitech | , | Gone |
| Menarini | L'Aquila, Italy | Small Molecules |
| AstronauTx | London, UK | Alzheimer's Treatments |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Integer | Alden, NY | Medical & Surgical Devices |
| Doloromics | , | Shut down Mar 2025 |
| Roche | Penzberg, Germany | Diagnostics |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| , | Website under construction, Feb 2024 - Nov 2025 | |
| Redpoint Research | , | Gone 2019 |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| TransGenRx | , | Bankrupt |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| Accellacare | Knoxville, TN | Clinical Research |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Novartis | Emeryville, CA | Diagnostics |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| , | Acquired by Stryker, Oct 2024 | |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| Bonenta | , | Website gone |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Translational Bioscience | , | |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| , | Acquired by IQVIA | |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| Denk Pharma | Munich, Germany | Generics |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Heart Repair Technologies | , | |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| Isolagen | , | Reorganized as Fibrocell Science |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Nina Biotherapeutics | , | Gone, after 2015 |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| Gennova Bio | Pune, India | mRNA vaccine |
| Dharma Therapeutics | , | Gone, 2013 |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Proteintech | Rosemont, IL | Research Antibodies |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Alderon Biosciences | , | Presumed gone |
| Getinge | Mumbai, India | Medical Technology |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| Singulex | , | Shut down Jun 2019 |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Lumanity | London, UK | Consulting |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| MILabs | Houten, Netherlands | Molecular Imaging |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| TFS | Lund, Sweden | Clinical Research |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| GlySens | , | Bankrupt Nov 2022 |
| Theracos | , | Renamed TheracosBio |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| Lyman Biopharma Consulting | , | Switched to writing |
| Partek | , | Acquired by Illumina, May 2024 |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Pharmaron | Xi'an, China | R&D Services |
| VasculoMedics | , | Gone 2019 |
| , | Acquired by IQVIA | |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| OxStem | , | Shut down 2021; Oxford spinout |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Catylix | , | Shut down Oct 2021 |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Chrysalis | Waltham, MA | GMP Space |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| Redoxis | Lund, Sweden | Drug development CRO |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Embecta | Parsippany, NJ | Diabetes Care |
| TrialStat Solutions | Montreal, QC | eClinical |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Medelis | Ypres, Belgium | Clinical Research |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| , | Website down Sep 2025 - Dec 2025 | |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Metis Laboratories | , | |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| DNAtrix | , | Gone late 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Entropia Biosciences | , | Shut Down June 2019 |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| RJS Biologics | , | Shut down Feb 2019 |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| Inform Genomics | , | Website Gone Nov 2018 |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| , | Bankrupt, ceased operations Mar 2026 | |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| Targovax | , | Renamed Circio, Apr 2023 |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Genuine Biosystem | Chennai, India | IVD Products |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Transave | , | Merged with Insmed Dec 2010 |
| Novotech | Auckland , New Zealand | Clinical Research |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Pharmaron | Louisville, KY | R&D Services |
| Integer | Clarence, NY | Medical & Surgical Devices |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| GT Molecular | Fort Collins, CO | PCR Kits |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| Terumo Medical | Elkton, MD | Medical Devices |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| CO.DON | Leipzig, Germany | Cell Therapies |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Genomadix | Kanata, ON | Portable PCR |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| Azad Pharma | Montreal, QC | APIs, generics |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Viropro | , | Bankrupt 2015 |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| Avema Pharma | , | Bought by PL Developments |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| Western Biologics | , | Dissolved, 1998 |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| Acumed | Madrid, Spain | Medical Implants |
| Avioq | Durham, NC | HIV Diagnostics |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| Medispect | , | Shut Down 2013 |
| Pharos Dx | , | Gone |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Pivotal BioSciences | , | Shut down late 2018 |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| Patrin Pharma | Skokie, IL | Generics |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Cambria Biosciences | , | Gone Feb 2008 |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Diatos | , | No website, founded 1999 |
| Predicine | Hayward, CA | Liquid Biopsy |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| Exodon | , | Website taken over, Jul 2014 |
| Quantificare | Suwanee, GA | Medical Imaging |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| Sea Medical Systems | , | Gone |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| Neural Analytics | , | Renamed NovaSignal |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| GT Biologics | , | Renamed 4D Pharma Research |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Triangle Insights Group | Durham, NC | Consulting |
| Bio Processing | , | Bought by Bio-rad |
| , | Shut down Jul 2026; aka Integrity Implants | |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| IvWatch | Newport News, VA | IV infiltration detection |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| Synedgen | Claremont, CA | Biofilm Control |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Arbutus Biopharma | Warminster, PA | RNAi |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Squarex | , | Gone as of Oct 2021 |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Texcell | Gronau, Germany | Contract Research |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| ROKIT | Seoul, Korea | Organ Regeneration |
| Alizyme | , | Bankrupt 2009 |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| , | Renamed Kapadi, Nov 2025 | |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| PKPD International | , | Attack website |
| XellSmart | Shanghai, China | Cell Therapy |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| Duality Biologics | Shanghai, China | ADCs |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| OptiVia Medical | , | Website looks pretty terrible |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| Stemetix | , | Shut down Apr 2021 |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Ocean Therapeutics | , | Shut down June 2013 |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Elan | , | Bought by Perrigo, Dec 2013 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| NantCell | , | Renamed ImmunityBio |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| GeneTrol | , | Merged with CytoPharm |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Neurosave | , | Gone 2018 |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Catalyst Clinical Research | Clinton, CT | Clinical research solutions to the global biopharmaceutical industry |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Altos Therapeutics | , | Gone Jun 2019 |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| Alexis Biotech | , | Dissolved May 2015 |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| SARcode | , | Bought by Shire Mar 2013 |
| Niveus Medical | , | Closed Dec 2017 |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| C3 Jian | , | Now C3J Therapeutics |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| InnoCare | Nanjing, China | Cancer Treatments |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| Zambon | Bresso, Italy | Small Molecules |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| BioConsulting International | , | Ancient website, presumed defunct |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Repco Development Technologies | , | Renamed 3Dispense |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| Castor | Claymont, DE | eClinical Trial Software |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| Biotechnical Services | , | Shut down Apr 2019 |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| DMD Therapeutics | , | Gone Nov 2018 |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| Medtronic | Memphis, TN | Medical Devices |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| AccuVein | Medford, NY | Vein Visualization |
| Bach Pharma | , | Shut down late 2023 |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| 14M Genomics | , | Shut down, Feb 2016 |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| PluroGen Therapeutics | , | Gone 2013 |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| Xencor | Pasadena, CA | Antibody Discovery |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| Thyritope Biosciences | , | Closed Oct 2016 |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Tarpon Biosystems | , | Gone by 2017 |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| NeuroTransit | , | Behind on taxes in CA |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| Bioneeds | Bangalore , India | Contract Research |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Gamma Therapeutics | , | Gone |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Altan Pharma | , | Acquired by Ethypharm |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Lacer | Barcelona, Spain | Small Molecules |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| , | Acquired by Galecto, Nov 2025 | |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| , | No news 2020 - Apr 2026 | |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| Kelliop | Newark, CA | Diagnostic Reader |
| CTIBIOTECH | Philadelphia, PA | Tissue Sample |
| NeurOptics | Irvine, CA | Pupillometry |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| StemBioSys | San Antonio, TX | Stem Cells |
| , | Renamed Grey Matters Health, Apr 2026 | |
| DDL | Irvine, CA | Device Testing |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| SCOLR Pharma | , | Closed Mar 2013 |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| Medica | , | Gone before 2019 |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Vesper Medical | Wayne, PA | Venous Stent |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| Forge Biologics | Grove City, OH | Biologics |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Vrata Therapeutics | Cambridge, | |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Retroject | , | Seems gone |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| Biomax Informatics | , | Acquired by Labvantage |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| Holloway America | Springfield, MO | Vessels, Tanks |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| Microphage | , | Bankrupt Jun 2013 |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| Origen Therapeutics | , | Gone |
| , | Seems renamed to Lusis Biosciences | |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Veracyte | South SF, CA | Cytology Diagnostics |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Eisai | Nutley , NJ | Small Molecules |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| ID Pharma | , | Acquired by I'rom Group |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| Proteintech | Manchester, UK | Research Antibodies |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| , | Part of SBO Hearing, Feb 2026 | |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| Vascular Genesis | , | Website gone Aug 2022 |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| Plaxgen | , | Shut Down 2019 |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| Iontas | , | |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| Eurosequence | , | Website gone Jan 2020 |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| Imstem Biotechnology | , | Website gone May 2021 |
| |
Heerenveen, Netherlands | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| |
Hamont-Achel, Belgium | Sharp is a leader in commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| nference | Cambridge, MA | Clinical AI |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| Quratis | Cheongju, Korea | Vaccines |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Aureon Biosciences | , | Insolvency Proceedings |
| Inovio Biomedical | , | Seems gone |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Altasciences | Harleysville, PA | Contract Research |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| SolaranRx | , | Website taken over |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Denizen Biologics | , | Shut down Mar 2023 |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| Pfizer | Surrey, UK | Consumer Healthcare |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Orion Genomics | St. Louis, MO | Biomarkers |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Dornier MedTech | Sillingy, France | Urology Devices |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Bioventus | Cordova, TN | Orthobiologics |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| Biomatters | , | Renamed Geneious |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| , | Rebranded as VivoSim, Apr 2025 | |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Piramal | Sellersville, PA | CDMO |
| Kylin Therapeutics | , | Sold |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| AbX Biologics | , | Renamed Abveris |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| Oligasis | , | Changed named to Kodiak Sciences |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| icometrix | Boston, MA | Imaging AI |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| NB Therapeutics | , | Gone |
| , | Website down Nov 2025 - Apr 2026 | |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Innogenix | Amityville, NY | Generics |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| Biotox Sciences | , | Renamed BTS Research |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Androclus Therapeutics | , | Closed, May 2007 |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Originus | , | Gone |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Conformis | , | |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| preclinics | Parma, Italy | Contract Research |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| , | Shut down Jan 2024 | |
| Applied NeuroSolutions | , | Gone |
| MedCision | , | Assets bought by MedCision, May 2018 |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Syneos Health | Princeton, NJ | Clinical Development |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| Cellanome | Foster City, CA | Multiomics Platform |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Mederi Therapeutics | , | Now Mederi-RF |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| METiS Technologies | , | |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Accellacare | Winston-Salem, NC | Clinical Research |
| MSM Protein Technologies | , | Gone Jun 2019 |
| EvON Medics | Ellicott City, MD | Medical Devices |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| Brighton Biotech | , | Only employee is an accountant |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| CranioVation | , | Shut down Jan 2022 |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| Regulome | , | Gone 2006 |
| Quartet Medicine | , | Wound down, Nov 2017 |
| Adams Clinical | Watertown, MA | Clinical Facility |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| Celvive | , | No news from 2012-2020 |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| QuantumBio | State College, PA | Protein characterization software |
| Encorium | , | Bankrupt |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| LunaDNA | , | Shutting down Jan 2024 |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Ignis Therapeutics | Shanghai, China | |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| Ceribell | Sunnyvale, CA | Fast EEG |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| DxTerity | Torrance, CA | Genomic Testing |
| SGS Quay Pharma | , | |
| , | Website down Jan 2026 - May 2026 | |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| ions.bio | Planegg, Germany | Biomarkers |
| BRAND | Wertheim, Germany | Liquid Handling |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| Ipca Laboratories | Mumbai, India | APIs |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| Anvyl | , | Website gone Jan 2021 |
| Eminent Services | Frederick, MD | Drug Services |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Cytosolix | , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed |
| Viatris (2) | Hyderabad, India | Small Molecules |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| RelonChem | Cheshire, UK | Generics |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| M2 Medical | , | Now Asante Solutions |
| Pfizer | McPherson, KS | Sterile Injectables |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| Padagis | Allegan, MI | Generics |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| , | Website down Jan 2026 - Mar 2026 | |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Trilobio | San Francisco, CA | Lab Automation |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| LifeSensors | , | Website hijacked Feb 2025 |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| , | Website down Jan 2026 - May 2026 | |
| Meristem Therapeutics | , | Defunct |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| , | Website down Nov 2025 - Apr 2026 | |
| Endomag | Cambridge, UK | Biopsy Tracer |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| Zai Lab | Beijing, China | Small Molecules |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Mabqi | Grabels, France | Antibody Discovery |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Lung LLC | , | Renamed Lung Biotechnology |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| , | Shut down Oct 2025 | |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| AlcaSynn | , | Renamed ChironWells |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| Corza Medical | Boulder, CO | Surgical Devices |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| , | Website down Sep 2025 - Dec 2025 | |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| Advantagene | , | Renamed Candel Therapeutics |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |