Taiwan - Biotech Companies - Career Pages
| Soteria Biotherapeutics | , | Website down Nov 2022 - Mar 2023 |
| NeuroNexus Technologies | Ann Arbor, MI | Electrophysiology Research Products |
| Solvo Biotechnology | Budapest, Hungary | Assays |
| Advancing Drugs | , | Website gone May 2020 - Sep 2020 |
| Pegbio | Hangzhou, China | Drugs for Chronic Diseases |
| METiS Technologies | , | |
| Dynamic Cell Therapies | , | Website down Feb 2025 - Jul 2025; fka Raqia Therapeutics |
| Vectron Biosolutions | Trondheim, Norway | Bioprocessing Services |
| Epic Medical Research | Red Oak, TX | Clinical Research & Services |
| Immunodiagnostic Systems | Poulily-en-Auxois Dijon, France | Immunoassay System |
| MS-Omics | , | Merged with Clinical-Microbiomics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| BCR Diagnostics | , | Website gone Apr 2019, Seems defunct |
| Sunho Biologics | Nanjing, China | Biologics |
| OM Pharma | Meyrin, Switzerland | Microbial derived immunotherapeutic products |
| SLC Consulting | , | Changed name to Lean Biologix, Jan 2014 |
| Clinical Trial Center North (CTC North & KG) | , | Acquired by Agenus, Feb 2022 |
| Pharmacosmos | Holbaek, Denmark | Iron Deficiency Medicines |
| Cellcion | , | Website gone, company going inactive |
| Hubro Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Cellular Ecosystems Therapeutics | , | Renamed Celsius Therapeutics, Jan 2018 |
| Orion Genomics | St. Louis, MO | Biomarkers |
| ProteinQure | Toronto, ON | Computational R&D tools to perform drug design in silico |
| Genetic Technologies Group | , | Renamed geneType |
| Byonoy | Hamburg, Germany | Microplate Readers |
| Artron BioResearch | Burnaby, BC | Antibodies, Antigens |
| CellVoyant | Bristol, UK | AI Cell Imaging |
| Flow Medtech | , | Website down Feb 2022 - Jul 2022 |
| Syd Labs | Hopkinton, MA | Antibodies, reagents, research supplies, etc. |
| , | Website gone Feb 2026 | |
| cmbio | Copenhagen, Denmark | Omics, Bioinformatics, Software Platforms |
| CellzDirect | , | Acquired by Life Technologies, Jan 2008 |
| Flocel | , | Website weird Dec 2023 - Jul 2024 |
| PreviPharma | Mannheim, Germany | Plasma Industry Services |
| VIVEbiotech | Donostia-San Sebastian, Spain | Lentiviral CDMO |
| Novo Nordisk | Clayton, NC | Diabetes, obesity, liver disease and other therapeutic areas |
| Synlico | South SF, CA | In Silico CAR T Drug Discovery |
| Sanofi | Mississauga, ON | Small Molecules, Biologics |
| , | Winding down, Dec 2025 | |
| , | Website down Oct 2025 - Feb 2026 | |
| Kinarus Therapeutics | , | Merged with distributor, Apr 2024; Sister company of Strekin |
| Freeline Therapeutics | , | Renamed Spur Therapeutics, Jun 2024 |
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Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| TcLand Expression | , | Website Gone |
| Kv1.3 Therapeutics | , | Shut down Nov 2018 |
| Vistin Pharma | Oslo, Norway | Generics |
| Aspire Biotech | Colorado Springs, CO | Biomaterials |
| TE Connectivity | Galway, Ireland | Contract Medical Devices |
| Apellis Pharmaceuticals | Hawthorn East, Australia | Cyclic peptide analog |
| PMV Pharma | Princeton, NJ | P53 regulators |
| Yumab | Braunschweig , Germany | Antibody Generation |
| Berlex | , | Now Bayer |
| Quantum Orthopedics | , | Renamed Spinal Elements |
| BianoGMP | Gera, Germany | Oligonucleotides |
| CytoReason | Tel Aviv, Israel | Machine Learning Drug Discovery |
| EOC Pharma | Taizhou, China | In licensing for Chinese market |
| Antibody Solutions | Santa Clara, CA | Antibody Development |
| Innogene Kalbiotech | Singapore, Singapore | Biologics, Biosimilars, Diagnostics |
| Advanced Tissue Sciences | , | Liquidated Mar 2003 |
| Targacept | , | Merged into Catalyst Biosciences, Aug 2015 |
| Boulder Diagnostics | , | Assets purchased by Oxford Immunotec, Aug 2014 |
| Seven and Eight Biopharmaceuticals | , | Website down, employees gone Jun 2024 |
| Aerial BioPharma | , | No employees on LI, no web updates since 2014, no info on whether active |
| Pharmaron | Cardiff, UK | R&D Services |
| SiranBio | Suzhou, China | siRNA, Oligonucleotide Therapies |
| Ontera | , | Website down Apr 2022 - Jun 2022, employees virtually all gone |
| ENSEM Therapeutics | Waltham, MA | Characterizing rare conformational states in drug targets |
| Galenea | , | Technology acquired by Q-State Biosciences, 2017 |
| Gentegra | , | Part of IntegenX |
| AbbVie | Irvine, CA | Small Molecules, Biologics |
| Helix BioMedix | , | No news 2017 - Aug 2025 |
| Prospect Bio | , | Website down Jun 2020 - Jan 2021 |
| Laekna Therapeutics | Shanghai, China | Small Molecules targeting cancer and liver diseases |
| Insero Health | , | Merged into Biscayne Pharmaceuticals, Oct 2015 |
| Kantar Health | , | Acquired by Cerner, Apr 2021, rebranded as Cerner Enviza |
| XW Laboratories | , | Renamed XWPharma |
| Teleflex Medical | Singapore, Singapore | Surgical and Medical Devices |
| Haystack Sciences | , | Acquired by insitro, Oct 2020 |
| Dynex Technologies | Chantilly, VA | Microplate Readers, Technology |
| SynerK | , | Website down Apr 2025 - Sep 2025 |
| Avra Medical Robotics | , | Reverse Merged with CardioVentures, Apr 2023 |
| Achira | San Francisco, CA | Atomistic foundation simulation models to power the future of drug discovery |
| Aignostics | Berlin, Germany | Biomarker Discovery, Translational Research, Digital Diagnostics |
| MyoKardia | , | Acquired by Bristol-Myers Squibb, Oct 2020, $13.1B |
| Vivia Biotech | Madrid, Spain | AML Diagnostic |
| Teleflex Medical | Madrid, Spain | Surgical and Medical Devices |
| Madam Therapeutics | , | Website down Feb 2024 - Jul 2024; Wound healing, may have drug application |
| Morton Grove Pharmaceuticals | , | Acquired by Wockhardt, Oct 2007 |
| Integrated Diagnostics (1) | , | Gone Jan 2009 |
| AOP Orphan Diseases | Bratislava, Slovakia | Orphan disease treatments |
| WuXi Apptec | Suzhou, China | All types of contract work for small molecules, devices |
| Molecular Loop | Woburn, MA | NGS Technology |
| Ascentage Pharma | Taizhou, China | Small molecule cancer therapeutics |
| Prelude Therapeutics | Wilmington, DE | Cancer Treatments |
| Techpool Biopharma | Guangzhou, China | Urinary-derived Biologics |
| Link Medicine | , | Closed Jan 2014. AstraZeneca bought some neuroscience small molecules |
| Dexcel Pharma USA | Parsippany, NJ | Generics |
| Capcium | , | Website down Feb 2024 - Aug 2024 |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Adavium Medical | , | Website gone Dec 2023 - May 2024 |
| Orchid Orthopedic Solutions | Baden-Dattwil, Switzerland | Contract Medical Device Work |
| Surfix Diagnostics | Wageningen, Netherlands | Photonic Diagnostics |
| Immunxperts | , | Became part of Q2 Lab Solutions, Feb 2024 |
| Imdaptive | , | Website from 2008 as of Jun 2019, seems unserious |
| Forest Laboratories | , | Bought by Actavis, Jul 2014, $25B |
| Serodopa Therapeutics | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Verva Pharmaceuticals | , | Liquidated May 2016 |
| Sarum Biosciences | , | website ©2007, last news 2013 |
| Nusano | Valencia, CA | Radioisotopes |
| Pepscan Therapeutics | , | Combined with Biosynth Carbosynth and Vivitide to become Biosynth, Sep 2022 |
| PPL Therapeutics | , | Sold in 2003 |
| CTL Immunotherapies | , | Merged with MiniMed and Allecure to become MannKind, 2001 |
| Shoreline Biome | , | Renamed Intus Bio, Oct 2022 |
| BioAMPS | , | Gone |
| Annexon Biosciences | Brisbane, CA | Neurodegenerative and autoimmune disorders |
| Leukosight | , | Gone, website is online pharmacy now |
| ReactDx | Melbourne, FL | Wireless Monitors |
| RSB SPINE | , | Website down Jul 2021 - Feb 2022 |
| Pulse Biomedical | , | Distributor |
| Avanos Medical | Alpharetta, GA | Pain Management, Respiratory, IV Devices |
| Stella Therapeutics | , | Closed, Dec 2017 |
| Indivior | North Chesterfield, VA | Addiction Treatments |
| Poly Pharmaceuticals | Owens Cross Roads, AL | Generics |
| Cuda Pharmaceuticals | , | Presumed gone |
| Nuclea Biotechnologies | , | Website gone Oct 2016, layoffs Jan 2016, Assets sold Apr 2017 |
| ProJect Pharmaceutics | Martinsried, Germany | Protein Formulation & Process Development |
| ACROBiosystems | San Jose, CA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Harbour BioMed | Natick, MA | Antibodies and fragments |
| Viva Biotech | Shanghai , China | Contract Research |
| Icon Bioscience | , | Acquired by pSivida, rebranded as EyePoint Pharmaceuticals |
| Genzyme | , | Acquired by Sanofi, 2011, $20.1B |
| Opko Health | Miami, FL | Biologics, Vaccines, Diagnostics, etc. |
| Aarkus Therapeutics | , | Renamed Aarvik Therapeutics |
| Ymir Genomics | , | Dissolved Jun 2021 |
| Amplified Sciences | West Lafayette, IN | Diagnostics |
| Fe3 Medical | , | Website hijacked Apr 2023 - Jun 2023 |
| Bazell Pharma | , | Acquired by Amzell, Mar 2021 |
| Arcuate Therapeutics | , | Shut down Mar 2021 |
| ImmuneID | , | Website down Dec 2023 - May 2024 |
| Rhythm Health | , | Renamed Motus Therapeutics |
| Ziopharm Oncology | , | Renamed Alaunos Therapeutics, Jan 2022 |
| VNUS Medical Technologies | , | Bought by Covidien, May 2009, $440M |
| MSD | Carlow, Ireland | Vaccines |
| Biojo Sciences | Seoul, Korea | Gene Therapy & Others |
| Relation Therapeutics | London, UK | Machine Learning Drug Discovery |
| Molecular Stethoscope | , | Renamed Superfluid Dx, Oct 2023 |
| Fyodor Biotechnologies | Baltimore, MD | Malaria Test |
| Aviria Biosciences | , | Disappeared |
| Aqua Pharmaceuticals | , | Acquired by Almirall, up to $400M |
| RDx BioScience | , | Website down Aug 2023 - Jan 2024; LI page gone Nov 2023 |
| WhiteLab Genomics | Paris, France | Cell & Gene Therapy Services |
| Biolab | São Paulo, Brazil | Small Molecules |
| Biocon | Bangalore, India | Fully Integrated Drug Company |
| Xiogenix | Muskego, WI | Automated processing equipment and engineering solutions for cell and gene therapy and tissue banking |
| KeyZell | Sevilla, Spain | Treatments and digital tools against cancer |
| Medannex | Edinburgh, UK | Monoclonal Antibody targeting Annexin-A1 |
| CPTx | South SF, CA | Gene-encoding single-stranded DNA |
| Capsida Biotherapeutics | Thousand Oaks, CA | AAV Gene Therapy |
| Adcentrx Therapeutics | San Diego, CA | Antibody drug conjugate |
| MetaMorphix | , | Changed to Scidera Genomics |
| Kernal Biologics | Cambridge, MA | mRNA Technology |
| Smith and Nephew | Andover, MA | Sports Medicine, Trauma, Wound Care, etc. |
| Aquinnah Pharmaceuticals | Cambridge, MA | ALS targeting drugs |
| Novosis | , | Acquired by Acino, 2006 |
| Adheren | , | Gone, 2016 |
| HTL Biotechnology | Javene , France | Pharmaceutical-grade Polymers |
| Covaris | Woburn, MA | DNA Sample Prep |
| Hollis-Eden Pharmaceuticals | , | Changed Name to Harbor Biosciences, Feb 2010 |
| Beacon Biosignals | Boston, MA | AI software/electroencephalography for neuro biomarker discovery |
| Castor | Claymont, DE | eClinical Trial Software |
| LiNA MEDICAL | Naerum, Denmark | Minimally invasive gynecology |
| Diversa | , | Merged with Celunol to become Verenium |
| EpiVax | Providence, RI | Bioinformatic tools for immunogenicity screening, vaccine design, services |
| Solta Medical | , | Acquired by Valeant, $236M Dec 2014 |
| Immunosyn | , | Charged with Securities Fraud |
| Second Sight | , | Merged with Nano Precision Medical, Aug 2022 to become Vivani Medical |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| GeneLink Biosciences | , | Website gone Jul 2018 |
| Pyranose Biotherapeutics | , | Website gone Apr 2022, not registered in CA |
| Ocularis Pharma | , | Website gone, Jul 2015 |
| Skyland Analytics | , | Acquired by IDBS, Nov 2021 |
| Oxford Pharma | , | Homepage not working, Jun 2019 |
| Meta-Iq | , | Website gone Jun 2020 |
| Talaria Antibodies | , | Inactive Mar 2024; fka LaCell |
| Aventis | , | Merged with Sanofi-Synthelabo, Apr 2004; Formed in 1999 when Rhône-Poulenc merged with Hoechst Marion Roussel |
| Alnara Pharmaceuticals | , | Bought by Eli Lilly, Jul 2010, $380M |
| , | Acquired by Millipore, Dec 2010 | |
| Forecyte Bio | , | Website down Feb 2025 - Jul 2025 |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Santen | Emeryville, CA | Ophthalmics |
| Meridian Life Science | Memphis, TN | Antibodies, Antigens, Proteins, PCR, Lab Stuff |
| Quantum Medical Metrics | , | President left in 2011, website still lists him |
| BlueLight Therapeutics | , | Shut down Oct 2021; fka Biodesy |
| , | Renamed Grey Matters Health, Apr 2026 | |
| Affitech | , | Gone |
| , | Acquired by Altaris, Mar 2025 | |
| FazaClo | , | Acquired by Azur Pharma 2007 |
| Celsee Diagnostics | , | Acquired by Bio-Rad, Apr 2020 |
| IRISYS | , | Acquired by Recro, Aug 2021 |
| Inoviv | London, UK | Bespoke Biomarker Tests |
| EpiBiome | , | Sold discovery platform to Locus Biosciences, Jul 2018 |
| Diality | Irvine, CA | Hemodialysis System |
| JSS Medical Research | Warsaw, Poland | Clinical Research & Consulting |
| Athenex | , | Chapter 11 Bankruptcy, May 2023 |
| Bexel Pharmaceuticals | , | Bought by Orchid Pharma, Aug 2006, $3M |
| Swedish Orphan Biovitrum | Stockholm, Sweden | Biologics |
| Akinion Pharmaceuticals | , | Seem to have disappeared after development status halted, 2016 |
| Solvo Biotechnology | Szeged, Hungary | Assays |
| Aviva Systems Biology | San Diego, CA | Antibodies, Peptides, Kits, etc. |
| EsoBiotec | , | Acquired by AstraZeneca, May 2025, $425M + $575M milestones |
| Magellan Diagnostics | , | Purchased by Meridian Biosciences, Mar 2016, $66M |
| NovaLead Pharma | Shrewsbury , MA | Small Molecules |
| Orphalan | Paris, France | Small molecule for Wilson's disease |
| Haemtech Biopharma Services | , | Renamed Prolytix, Feb 2022 |
| Brand Institute | Miami, FL | Global pharma and biotech branding agency that partners on naming over 75% of new drugs every year |
| Oceana Therapeutics | , | Acquired by Salix Pharmaceuticals, Nov 2011, $300M |
| Syndexa Pharm | , | Closed Jul 2013 |
| Athena Discovery | , | Website down Jan 2025 - Jun 2025 |
| Corvas International | , | Acquired by Dendreon Pharmaceuticals, Nov 2003 |
| Genetics Squared | , | Changed name to Everist Health Jan 2011 |
| Aseda Sciences | Oakland, MD | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| PHT Corporation | , | Acquired by ERT, May 2015 |
| Imnewrun Bioscience | Suwon, Korea | BBB-Penetrating Antibodies |
| Eckert and Ziegler | Berlin, Germany | Isotopes for Medical Use |
| Atrility Medical | Madison, WI | Arrhythmia Monitoring |
| Centrix Pharmaceutical | , | Website down Feb 2021 - Jul 2021 |
| DesignMedix | , | Shut down Aug 2020 |
| Perfuze | Galway, Ireland | Stroke Treating Technology |
| GEROPHARM | Moscow, Russia | Large drug maker |
| Pulmagen Therapeutics | , | Website gone Jan 2019; Created out of Argenta Discovery's drug operations when it was sold to Charles River |
| Evvy | New York, NY | At-home vaginal microbiome test |
| ONFAB | Cheshire, UK | Custom-designed, single-use and retrofit flexible isolators |
| Ackley Hartnett | Moorestown, NJ | Tablet Machines |
| Chrysalis | Burlington, MA | GMP Space |
| PharmaGap | , | Shut down 2013 |
| PepSep | , | Acquired by Bruker, Feb 2022 |
| Annai Systems | , | Website down Jul 2021 - Feb 2022 |
| Brainvectis | , | Acquired by AskBio, Apr 2020 |
| Beximco Pharmaceuticals | Dhaka, Bangladesh | Generics |
| OncoResponse | Seattle, WA | Immuno-oncology antibodies |
| SelectX | , | Website hacked; No updates since 2011 |
| A&G Pharmaceutical | , | Still technically active Jan 2022, but no progress in a decade |
| Tides Medical | Lafayette, LA | Biologics |
| Bioagilytix | Hamburg, Germany | Bioanalytical services, immunoassays, cell-based assays |
| Coloplast | Beijing, China | Wound care, surgical, bladder, bowel devices |
| Metrohm | Houston, TX | Lab Data Management Software |
| Concert Pharmaceuticals | , | Acquired by Sun Pharma, Mar 2023 |
| Acrotech Biopharma | East Windsor, NJ | Specialty Pharmaceuticals |
| Gala Biotech | , | Acquired by Catalent Pharma Solutions, ~Jul 2007 |
| Tactile Medical | Minneapolis, MN | Wraps for Lymphedema Patients |
| IntegenX | , | Acquired by Thermo Fisher, Mar 2018 |
| Riemser Pharma | , | Acquired by Esteve, Jan 2020 |
| NanoVation Therapeutics | Vancouver, BC | Gene Therapy Delivery |
| Cleveland Diagnostics | Cleveland, OH | Cancer Diagnostics |
| Avanti Therapeutics | , | Now Chikojee Therapeutics (more or less) |
| B-MoGen Biotechnologies | , | Folded in to R&D Systems |
| Compass Therapeutics | Boston, MA | Antibody Therapies |
| RK Pharma | Pearl River, NJ | Generics |
| Ironshore Pharmaceuticals | , | Acquired by Collegium, Sep 2024, $525M; Shut down, Oct 2017, brought back Sep 2018 |
| OneCell Diagnostics | , | Renamed 1Cell.Ai, Apr 2025 |
| Biacore | , | Acquired by GE, Jun 2006, $390M |
| Stryker | Portage, MI | Medical Devices |
| BioGenerics | , | Renamed Coherus Biosciences, Apr 2012 |
| Boston Biochem | , | Acquired by Techne, Apr 2011 |
| , | Website down Oct 2025 - Dec 2025 | |
| TechLab | Blacksburg, VA | Intestinal diagnostics |
| Noile-Immune Biotech | Tokyo, Japan | Immuno-oncology |
| International Medical Industries | Pompano Beach, FL | Compounding Pharmacy Drug Delivery |
| Zymeworks | Vancouver, BC | In Silico Biologics Development |
| ChemOvation | St Helens, UK | Pharmaceutical Services |
| Proliant Biologicals | Feilding, New Zealand | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Mott | Farmington, CT | HPLC system components, Filtration |
| Deverra Therapeutics | Seattle, WA | Cell Therapies |
| Thompson Surgical Instruments | Traverse City , MI | Surgical Retraction Device |
| Corza Medical | Jestetten, Germany | Surgical Devices |
| Ashvattha Therapeutics | Redwood City, CA | Nanomedicine Delivery |
| Stellar Pharmaceuticals | , | Changed name to Tribute Pharmaceuticals Jan 2013 |
| Certara | Paris, France | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| NeurMedix | , | Shut down June 2021; fka Reserva |
| Endogenx | , | Website Gone Dec 2013 |
| Mission Bio | South SF, CA | Single-cell nucleic acid characterization |
| Lonza | Vallensbaek Strand, Denmark | Contract Manufacturing, Development; Lab Systems, Research Products |
| Minakem | Beuvry-la-Forêt, France | API Manufacturing |
| Nogra Pharma | , | Bought by Celgene, Apr 2014, $710M |
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Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Xsensio | Lausanne, Switzerland | Lab-on-skin |
| Avant Diagnostics | , | Assets acquired by OncBioMune, Jun 2020 |
| Almon Therapeutics | , | No business filings Aug 2022 - Feb 2025; Website under construction, Feb 2024 - Dec 2024; Residential Address Feb 2024 |
| Galen Biotechnologies | , | Website gone Apr 2019, no annual report filed 2017 or 2018 |
| Abeome | , | Merged with Biophtha to become Lanier Biotherapeutics, Oct 2021 |
| ARC Medical Devices | Richmond, BC | Reduction of harmful and painful surgical adhesions through its innovative medical devices |
| MDR Laboratories | Sahmbrook, UK | Biocompatibility Services |
| TyrNovo | , | Bought by Kitov Therapeutics, Jan 2017, $2M + $1.8M stock |
| Schwarz Pharma Manufacturing | , | Acquired by UCB 2006 |
| Alizyme | , | Bankrupt 2009 |
| Jerini | , | Acquired by Shire, 2008 |
| PulmoSonix | , | Merged with PulmoSonix to become iSonea, 2011 |
| Allergenics Inc | , | Closed Mar 2007 |
| Curevo Vaccine | Bothell, WA | Vaccines |
| Lumenis | Chatswood, Australia | Energy-based medical treatments |
| Excelya | Boulogne, France | Clinical Research |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Vishpha | Zhytomyr district , Ukraine | Generics |
| C.R. Bard | , | Acquired by BD, Dec 2017, $24B |
| Plas-Tech Engineering | Lake Geneva, WI | Medical Device and Contract Manufacturing |
| , | Website down Nov 2025 - Apr 2026 | |
| Elevar Therapeutics | Seoul, Korea | Oncology Treatments |
| Bioforce Nanosciences | , | Shut Down Prior to Aug 2014 |
| Zelluna Immunotherapy | Oslo, Norway | TCR cancer cell therapy |
| GoodCell | , | Website down Jun 2023 - Dec 2023 |
| Eton Pharmaceuticals | Deer Park, IL | 505(b)(2) drugs |
| Antegrin Therapeutics | , | Merged with Cascadia Therapeutics to become Indalo Therapeutics, Oct 2016 |
| CytoSorbents | Berlin, Germany | Blood Purification Therapy |
| Align Technology | Tempe, AZ | Teeth alignment |
| Bonum Therapeutics | Seattle, WA | Better protein therapeutics |
| Guided Therapy Systems | , | Website gone Jun 2022 |
| Halo Genomics | , | Bought by Agilent |
| Blu Pharmaceuticals | , | Acquired by PuraCap, Mar 2016 |
| , | Website down Aug 2025 - Jan 2026 | |
| Sinogen Pharmaceutical | , | Website down Dec 2019 - May 2020 |
| Arrys Therapeutics | , | Became subsidiary of Kyn Therapeutics |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Lumeda | , | Merged with Cytoveris to become OncoLux, Jun 2025 |
| NBE Therapeutics | , | Acquired by Boehringer Ingelheim, Dec 2020, €1.18B |
| Aber Instruments | Alexandria , VA | Dielectric spectroscopy for live cell density readings |
| TruGenomix | , | Renamed Polaris Genomics |
| Adagio Therapeutics | , | Renamed Invivyd, Sep 2022 |
| AIT Therapeutics | , | Renamed Beyond Air, Jun 2019 |
| IDT Australia | Boronia, Australia | Contract Manufacturing |
| QT Ultrasound | , | Renamed QT Imaging |
| ADS BIOTEC | Chiba, Japan | Lab Instruments, Consumables |
| Nanovelos | , | Subsumed into Nanogroup |
| Nutrinia | , | No website Dec 2018 - Aug 2021; No news since 2015 |
| DJO Global | , | Renamed Enovis, Apr 2022 |
| Anju Life Sciences Software | Berchem, Belgium | Life Sciences Software |
| Pharmacia | , | Merged with Upjohn, Aug 1995 to become Pharmacia & Upjohn |
| BAROnova | , | Website down Apr 2021 - Sep 2021 |
| DVS Sciences | , | Acquired by Fluidigm, Jan 2014, $207M |
| DeNovo Sciences | , | Renamed Celsee Diagnostics, Oct 2015 |
| NeuroDerm | Rehovot, Israel | Reformulations of established drugs |
| Beacon Discovery Inc | , | Acquired by Eurofins Scientfiic, Feb 2021; Spun out of Arena Pharmaceuticals, Sep 2016 |
| Anju Life Sciences Software | Pune, India | Life Sciences Software |
| Norwood Medical | Dayton, OH | Medtech Manufacturing |
| Dorphan | , | Shut down so owner could spend more time skiing |
| KalVista Pharmaceuticals | Framingham, MA | Ophthalmology Products |
| Akceli | , | Shut down, Sep 2004 |
| Amypopharma | , | Website down Apr 2023 - Sep 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| Aptevo Therapeutics | Seattle, WA | Oncology and hematology therapeutics, Bispecific Antibody |
| Suzhou Ribo Life Science Company | Kunshan, China | RNAi |
| Sontec Instruments | Centennial, CO | Surgical Instruments |
| Fortify Therapeutics | , | Shut down Mar 2021 |
| S-biomedic | Ghent, Belgium | Proprietary skin microbiome modulation tech |
| Immuneering | Cambridge, MA | Bioinformatics for genomics |
| DegenRx | , | No news 2019 - Aug 2024; employees list other jobs on profiles |
| Flomics | Barcelona, Spain | Molecular Biopsies |
| Tedor Pharma | Cumberland, RI | Contract Manufacturing, Small Molecules |
| Tolerion (old) | , | Changed name to Bayhill Therapeutics Nov 2002 |
| Brii Biosciences | San Mateo, CA | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Veryan Medical | Galway, Ireland | Helical Stent |
| Lakefront Biotherapeutics | Mechelen, Belgium | Drug & Antibody Therapy Discovery |
| Plasmidsaurus | South SF, CA | Genome Sequencing Services |
| Xlumena | , | Acquired by Boston Scientific Apr 2015, $62.5M |
| Countable Labs | Palo Alto, CA | Identifying Rare Events in PCR Workflow |
| Agilent | Beijing, China | High-Throughput Screening Equipment, Imaging instruments |
| InnAVasc Medical | , | Acquired by W.L. Gore, Aug 2022 |
| Inviragen | , | Bought by Takeda, May 2013 Announced |
| Genoptix | , | Bought by Novartis Jan 2011, sold off Jan 2017, bought by Neogenomics, Dec 2018, $125M + 1 million shares |
| Vivatides Therapeutics | Woburn, MA | RNA Therapeutics |
| Epistem | , | Website down, Jul 2023 - Nov 2023 |
| DZS Clinical Services | , | Renamed Medfiles, Jan 2023 |
| BRL Medicine | Shanghai, China | Cell & Gene Therapy Platforms |
| Ascentawits Pharmaceuticals | Shenzhen, China | Small Molecule |
| Dendreon | Seattle, WA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Bioprospecting | , | Renamed Soricimed Biopharma, 2010 |
| , | Acquired by Olon, 2024 | |
| Revivicor | , | Acquired by United Therapeutics, 2011, $7.6M |
| Interline Therapeutics | , | Website down Jun 2024 - Nov 2024; CA filings late Feb 2024 |
| Anglian Pharmaceuticals | , | Now part of Crescent Pharmaceuticals |
| BioHealthWays | , | Website down Nov 2024 - Mar 2025; Residential Address Jul 2019 |
| Orchid Chemicals & Pharmaceuticals | , | Renamed Orchid Pharma |
| Strand Therapeutics | Boston, MA | Gene Therapy |
| Rytvel Biotechnology | , | |
| Rivanna Medical | Charlottesville, VA | Ultrasound |
| Noctrix Health | Pleasanton, CA | Device for restless Leg |
| ZiJian Biotechnology | Shenzhen, China | Diagnostics |
| Oncocyte | , | Renamed Insight Molecular Diagnostics, Jun 2025 |
| EpimedX | , | Website Gone Jan 2018; Business Registration Delinquent |
| Charles River Laboratories | Sulzfeld, Germany | Research Animal Models and Preclinical Research |
| AMLo Biosciences | Newcastle upon Tyne, UK | Prognostic Melanoma Biomarker Technology |
| H.E.L. Group | Princeton, NJ | Parallel and high pressure biotechnology lab equipment |
| InventisBio | Shanghai, China | Oncology & Metabolic Diseases |
| Sungen Biomedical | Beijing, China | Monoclonal Antibodies |
| Axentis Pharma | , | Company appears active in court, doubtful they are scientifically active |
| Nexomics Biosciences | Rocky Hill, NJ | Protein & structural biology services |
| Ataxion | , | Merged into Luc Therapeutics, Mar 2017 |
| vTv Therapeutics | High Point, NC | Small molecules |
| Vadovations | , | No website. Oklahoma based, Blood pump |
| CELLSCRIPT | Madison, WI | RNA for Translation |
| EPD Biotherapeutics | , | |
| ACMI | , | Acquired by Gyrus, 2005, $500M |
| Imricor Medical Systems | Burnsville, MN | MR-Guided Ablations |
| LaCell | , | Merged with Obtala Sciences, became Talara Antibodies |
| Apricus Biosciences | , | Merged with Seelos Therapeutics, Jan 2019 - will change name to Seelos |
| SynZyme Technologies | , | Renamed AntiRadical Therapeutics |
| Kither Biotech | Torino, Italy | Therapies for the treatment of rare pulmonary diseases |
| Bora Biologics | San Diego, CA | Contract Biologics |
| Thoratec | , | Bought by St. Jude Medical, Oct 2015, $3.4B |
| Carigent Therapeutics | , | Had a grant in 2008. No info for a long time |
| Mindshare Medical | , | Renamed RevealDx |
| , | Assets moved to Co-Diagnostics, 2013 | |
| B. Braun | Bethlehem, PA | Infusion therapy and pain management |
| Sinusys | , | Shut down 2023 |
| Elevar Therapeutics | Fort Lee, NJ | Oncology Treatments |
| Curadigm | , | folded into Nanobiotix |
| Astra Biotech | Berlin, Germany | In Vitro Diagnostics |
| Bioseek | , | Bought by Asterand Nov 2009, Sold to DiscoveRx Nov 2012 |
| Neuron23 | South SF, CA | AI-drug discovery |
| , | Acquired by IQVIA | |
| Monaghan Medical | Plattsburgh, NY | Holding Chambers |
| 3B BlackBio | Bhopal, India | PCR products |
| ImaginAb | Inglewood, CA | Imaging Products, Antibodies |
| Tangram Therapeutics | London, UK | In-Silico Drug Discovery |
| NimbleGen | , | Bought by Roche, renamed Roche Nimblegen, some tech sold to Arrowhead |
| SK Biopharmaceuticals | Gyeonggi, Korea | Neuro Treatments |
| Liveon Biolabs | Tumakuru, India | Contract Pharmaceutical Research |
| MediWound | Yavne, Israel | Wound & Burn Care |
| Cdymax | Bangalore, India | APIs |
| Dropworks | , | Acquired by Bio-rad, 2021 |
| Nanolek | Moscow, Russia | Biosimilars, Vaccines, Contract Manufacturing |
| Sovato | Santa Barbara, CA | Robotic-Assisted Surgery |
| Conformetrix | , | Renamed C4X Discovery Jul 2013 |
| , | Website down Dec 2025 - Apr 2026 | |
| LS9 | , | Bought by Renewable Energy Group, Jan 2014 |
| Helios Biosciences | , | Bankrupt. Gone 2011. Assets seem to have been purchased by AventaCell BioMedical |
| Feldan Therapeutics | Quebec City, QC | Peptide-based Intracellular Delivery Technology |
| Flare Therapeutics | Cambridge, MA | Therapeutics Targeting Transcription Factors |
| Vivopath | , | Acquired by Charles River, Jul 2014 |
| SMERUD Medical Research Group | Oslo, Norway | Full Service Clinical Research Organization |
| DxTech | , | Seems gone. No info Dec 2015 |
| Ampac Fine Chemicals | , | part of SK pharmteco |
| Bioserv America | , | Shut down Aug 2024 |
| Comprehensive Clinical Research | , | Website taken over Sep 2020 |
| TBD Pharmatech | Tartu, Estonia | API CDMO |
| Nanosonics | Sydney, Australia | Ultrasound |
| Eliem Therapeutics | , | Renamed Climb Bio, Oct 2024 |
| AFID Therapeutics | , | Gone 2012 |
| ExpreS2ion Biotechnologies | Hørsholm, Denmark | Expression System for Recombinant Protein Production |
| CHAIN Biotech | Nottingham, UK | Microbiome therapeutics |
| Viant Medical | Upland, CA | Contract Medical Devices |
| Delpharm | Brétigny-Sur-Orge, France | Contract Manufacturing |
| QS Pharma | , | Acquired by Quotient Clinical, 2017 |
| NeoTherma Oncology | , | Home page taken over by scammy reveiws |
| Frontier Scientific Solutions | Wilmington, NC | Cold Storage |
| ACS Biomarker | , | Shut down 2024; Website down Nov 2024 - Jan 2025 |
| SARomics Biostructures | Lund, Sweden | Structure-Based drug discovery services |
| PhenoVista Biosciences | San Diego, CA | Phenotypic assay services |
| Octagen | , | Assets bought by Ipsen, 2008 |
| Valens Therapeutics | , | Dissolved, Nov 2014 |
| Elex Biotech | , | Website down Feb 2024 - Jul 2024 |
| Axol Bioscience | Cambridge, UK | Human Cell Culture Products |
| Cranford Pharmaceuticals | , | Seems like they were just a company that sought an ANDA to sell on |
| Epic Therapeutics | , | Acquired by Baxter, Nov 2002, $50M+ |
| Calithera Biosciences | , | Liquidating, Jan 2023 |
| Weatherden | London, UK | Clinical Consulting |
| Fresenius Kabi | Melrose Park, IL | Contract Manufacturing |
| Nemod Biotherapeutics | , | Assets bought by Glycotope Biotechnology 2007 |
| Hepion Pharmaceuticals | Edison, NJ | Antiviral Therapies |
| Mucodel Pharma | , | Website down/hijacked Sep 2021 - Dec 2021 |
| Cellens | Boston, MA | Nanoscale Cancer Diagnostics |
| Evergreen Theragnostics | Springfield, NJ | CSMO, Radiochemistry, Clinical & Commercial Manufacturing |
| Leucid Bio | London, UK | Cell Therapy |
| Biowe Technology | Beijing, China | Lab products, Liquid Handling |
| Aequus Biopharma | , | Owned by CTI Biopharma, no news since 2012, no employees on LinkedIn |
| , | Website down Oct 2025 - Feb 2026 | |
| Bioeksen | Istanbul, Turkey | Molecular Diagnostics |
| , | Renamed Dasher Neuroscience, Mar 2026 | |
| Cellenion | Lyon, France | Single Cell Testing |
| Retrogen | San Diego, CA | Genomics & Diagnostics |
| CytoBioscience | , | Acquired in Reverse Merger, entity renamed Inventa Biotech |
| MDQuest | , | Website Down Feb 2025 |
| Carmenta Bio | , | Acquired by Progenity, Apr 2015 |
| Cellomics | , | Acquired by Fisher Scientific, Aug 2005, $49M |
| VelaVigo | Shanghai, China | Antibodies, ADCs |
| , | Website down Jan 2026 - May 2026 | |
 |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Delta4 AI | Vienna, Austria | AI Drug Discovery |
| Cellstate Biosciences | , | Website down Jan 2025 - Jun 2025; Residential Address, Aug 2022 |
| 1CellBio | , | Gone Jun 2019 |
| Cegrogen Biotech | , | No news 2017-2023, can't find any registration info Nov 2023 |
| Prometheon Pharma | , | Website down Sep 2021 - Jan 2022 |
| OxyPharma | , | Website not updated in five years, emails bounced |
| MarvelBiome | Woburn, MA | Microbial Therapeutics |
| Cabaletta Bio | Philadelphia, PA | Chimeric Auto Antibody Receptors |
| Tissue Regenix | Leeds, UK | Replacement Body Parts |
| Gilead | Edmonton, AB | Small Molecules |
| Arrowhead Pharmaceuticals | Pasadena, CA | RNAi |
| RQX Pharmaceuticals | , | Acquired by Amgen, Feb 2013, $111M |
 |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Abbott | Donegal, Ireland | Diagnostics |
| RayzeBio | San Diego, CA | Radiopharmaceuticals Therapy for Cancer |
| Abgent | , | Renamed Abcepta, 2019 |
| Norgine | Vienna, Austria | Specialty Pharma |
| Harrison Clinical Research | , | Merged with Synteract, became SynteractHCR |
| Biobase | , | Bought by Qiagen, May 2014 |
| miniPCR bio | Cambridge, MA | Miniature PCR machine |
| Piramed Pharma | , | Acquired by Roche, Apr 2008, $160M + $15M milestones |
| Advion Interchim Scientific | Harlow, UK | Immunoassays |
| SpliSense | Jerusalem, Israel | Antisense Oligonucleotides |
| MultiOmic Health | London, UK | AI-enabled precision medicine for metabolic conditions |
| Totient | , | Acquired by Absci, Jul 2021 |
| , | Shut down Oct 2025 | |
| Terumo Medical | Ann Arbor, MI | Medical Devices |
| Protagonist Therapeutics | Brisbane, Australia | Oral peptides |
| Iconix Biosciences | , | Acquired by Entelos, Aug 2007 |
| Zikani Therapeutics | , | Acquired by Eloxx Pharmaceuticals, Apr 2021; fka Macrolide Pharmaceuticals |
| Methapharm | Brantford, ON | Specialty Pharmaceuticals |
| VSPharmTech | Seagu, Korea | Small Molecules for Cancer |
| Glenveigh Medical | , | Website down Sep 2024 |
| Panaxium | Aix-en-Provence, France | Brain-Machine Interface |
| Sillar Clinical | Deurle, Belgium | Clinical Research |
| Silence Therapeutics | London, UK | RNAi |
| , | Renamed Filana Therapeutics, Mar 2026 | |
| Immuneel Therapeutics | Bengaluru, India | CAR-T Cell Therapy |
| Oncology Pharma | , | Website down Feb 2024 - May 2024; Business filings late, Jul 2023; Formerly an internet/networking company, rebranded and became a drug delivery company Jun 2019 |
| Accelus | Palm Beach Gardens, FL | Minimally Invasive Surgical Technology |
| MyBioSource | San Diego, CA | ELISA Kit, Recombinant Protein, Antibody & custom kit productions. MyBioSource.com: One-Stop Reagent Shop with nearly 2 million Life Science Products. |
| Upstream Bio | Waltham, MA | Therapies for allergic, inflammatory conditions |
| Arbor Biotechnologies | Cambridge, MA | CRISPR enzymes |
| EmeritusDX | Lake Forest, CA | Cancer Diagnostics |
| UCB Pharma | Leuven, Belgium | Small Molecules, Biologics |
| Cascade Chemistry | , | Acquired by Aceto, Jun 2021 |
| OncoCare Therapeutics | , | No website Jan 2020 - Jul 2024 |
| AdeptBio | , | Bought by Asterand Bioscience, Aug 2015 |
| Genesoft Pharmaceuticals | , | Acquired by Genome Therapeutics, Nov 2003 |
| OmniAb | Oro Valley, AZ | Antibody repertoires and high-throughput screening technologies |
| Amerigen Pharmaceuticals | , | Website down Jan 2020 - Dec 2020 |
| LiquiLume | , | Website gone, Mar 24, 2015 |
| LumiraDx | , | Acquired by Roche, Jul 2024, $295M |
| Novellus Therapeutics | , | Acquired by Brooklyn ImmunoTherapeutics, Jul 2021 |
| Celvive | , | No news from 2012-2020 |
| Juvaris | , | Licensed most assets. Virtual company, just gets money from licensing |
| Tetra Discovery Partners | , | Renamed Tetra Therapeutics, Aug 2019 |
| APCure | , | Website redirects to AltraBio, Feb 2019 |
| Tarix Pharmaceuticals | , | Effectively changed name to Tarix Orphan |
| PainTEQ | Tampa, FL | Sacroiliac Joint Stabilization Device |
| Bioferment | , | Merged with Sapec & Cernitin in 1994 to become Cerbios-Pharma |
| Vivo Bio Tech | Hyderabad, India | Contract Drug Development & Discovery |
| Caprico Biotechnologies | Norcross, GA | Flow Cytometry Products & Services |
| Exo Imaging | Santa Clara, CA | Ultrasound Platform |
| Rayner Intraocular Lenses | West Sussex, UK | Intra-Ocular Lenses |
| NexEos Diagnostics | , | Renamed NexEos Bio |
| Mercury Biomed | , | Website down Mar 2024 - Jul 2024 |
| OCON Therapeutics | Modiin, Israel | Intrauterine Drug Delivery |
| Fluid Biotech | , | Renamed Fluid Biomed, late 2022 |
| IDM Pharma | , | Acquired by Takeda |
| AUM Biosciences | Singapore, Singapore | Treatments for Asia-Prevalent Cancers |
| Momenta Pharmaceuticals | , | Acquired by J&J, Oct 2020, $6.5B |
| Systagenix | , | Acquired by KCI, Oct 2013, $485M |
| China Medical Systems | Hong Kong, China | Small Molecules, Monoclonal Antibodies |
| , | Website down Jan 2026 - May 2026; fka Intiva Biopharma | |
| Tybema BioSolutions | , | Website gone Sep 2017, no employees |
| Bexorg | New Haven, CT | Dead Brains for Drug Discovery |
| KARL STORZ Endoscopy | Singapore, Singapore | Endoscopy |
| Dipharma | Mereto di Tomba, Italy | APIs, Generics |
| Varex Imaging | Salt Lake City, UT | X-ray Imaging Components |
| GenVivo | San Marino, CA | Proprietary Gene Delivery Technology |
| Singleron Biotechnologies | Suzhou, China | Single-Cell Sequencing, Service Lab |
| Volution Immuno-pharmaceuticals | , | Merged with Celsus to become Akari Therapeutics, Aug 2015 |
| Wellmarker Bio | Hanam, Korea | Biomarker-based cancer drugs |
| bioRASI | Aventura, FL | Clinical Research |
| Progenitor Life Sciences | , | Website down Feb 2022 - Jul 2022 |
| JRX Biotechnology | , | Filings late Sep 2022 - Oct 2023, single person |
| SCTbio | Prague, Czech Republic | Cell & Gene Therapy Services |
| Safis Solutions | , | Acquired by Pharmalex, Apr 2017 |
| Allurion Technologies | Natick, MA | Gastric Balloon |
| LW Scientific | Lawrenceville, GA | Lab Equipment |
| Bioxell Pharma | , | Website gone, Sep 2018 |
| Millennium Pharmaceuticals | , | Acquired by Takeda, May 2008, $8B, eventually rebranded as Takeda Oncology |
| Biosim AI | , | Merged with Deep Origin, Jan 2024 |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| Incara Pharmaceuticals | , | Renamed Aeolus Pharmaceuticals |
| Synthomics | , | Website down Oct 2020 - Mar 2021 |
| , | Liquidation, Jun 2025 | |
| ImmunID | , | Patents acquired by Adaptive Biotechnologies, Site redirecting to Adaptive. Presumed defunct since url was involved. |
| HepatoSys | , | Website down Dec 2020 - Jan 2021 |
| GlycoMimetics | , | Acquired by Crescent Biopharma, Jun 2025 |
| Resolys Bio | , | Website Down May 2024 - Nov 2024 |
| Talee Bio | , | Renamed Spirovant Sciences |
| Boan Biotech | Nanjing, China | Biosimilar Antibodies |
| Aspen Biopharma | , | Renamed Venaxis Dec 2012 |
| c-Lecta | Leipzig, Germany | Enzymes, Microbial Strains, Contract Manufacturing |
| Mavupharma | , | Acquired by AbbVie, Jul 2019 |
| Celularity | Warren, NJ | Placenta-derived stem cells |
| ColubrisMX | , | Renamed ENDOQUEST robotics, Jun 2022 |
| Mabworks Biotech | Beijing, China | Antibodies, ADCs |
| Avantia Labs | Horsham, PA | Bioanalytical Solution for Cell & Gene Therapy |
| Alchemab Therapeutics | London, UK | Human-derived antibodies |
| OxSyBio | , | Website down Mar 2020 - Dec 2020 |
| CavtheRx | , | Website down Nov 2022 - Feb 2023; Yale Startup from 2014 |
| Satsuma Pharmaceuticals | Durham, NC | Drug Delivery Tech for Migraine |
| Symbient Product Development | , | Acquired by Gener8, Feb 2020 |
| Zetra Biologicals | , | Gone |
| Animantis | , | Website down Oct 2021 - Feb 2022 |
| Drumroll Health | , | Seems to have pivoted to data analytics; fka Transparency Life Sciences |
| , | Website down Jan 2026 - May 2026; fka Phosphagnics; Company switched to biotech in 2004 | |
| Bioclinica | , | Merged with ERT, 2021 |
| Sequenom | , | Bought by LabCorp, Sep 2016, $371M |
| T-cell Factory | , | Bought by Kite Pharma Mar 2015 €20M |
| Progen Biotechnik | East Hartford, CT | Antibodies, in vitro diagnostics, ELISA, AAV |
| EnBiotix | , | Acquired by Polyphor, Oct 2021 |
| Fairhaven Pharmaceuticals | , | Acquired by Liminal BioSciences, Jul 2020 |
| GenoMatix | , | Acquired by Intrexon |
| BioXcel Therapeutics | New Haven, CT | Sublingual thin film formulation, oral small molecule |
| Rejuvenate Bio | San Diego, CA | Gene Therapy for Aging |
| Sana Biotechnology | Seattle, WA | Cell & Gene Therapies |
| Pharnext | , | Website down Oct 2024 - Mar 2025 |
| Cybrexa Therapeutics | New Haven, CT | Small Molecule DNA repair Inhibitors |
| Vyrix Pharmaceuticals | , | Merged with Luoxis to become Aytu Bioscience, Apr 2015; originally spun out of Ampio |
| GeneCentric Therapeutics | Durham, NC | Cancer Biomarker, Drug Discovery |
| Quay Pharma | , | Acquired by SGS, Renamed SGS Quay Pharma, Jan 2024 |
| EAG Laboratories | Raleigh, NC | Analytical & Synthesis Services |
| Neurocea | , | Website down Apr 2022 - Aug 2022 |
| Menarini | Firenze, Italy | Small Molecules |
| Nafas Medical | , | Renamed Tioga Cardiovascular, Apr 2019; fka Nafas Medical |
 |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| CardioVax | , | Renamed Abcentra, Jan 2019 |
| ALX Oncology | South SF, CA | Immuno-oncology |
| Somru Bioscience | Charlottetown, PE | Antibodies, ELISA, etc. |
| JAJ International | , | Website not working, redirecting strangely |
| Topokine Therapeutics | , | Acquired by Allergan, Apr 2016, $85M + milestones |
| PharmAkea Therapeutics | , | Split company into ATXCo and PharmAkea - sold ATXCo to Blade Therapeutics, PharmAkea to Galecto |
| JADBio | Los Angeles, CA | Machine Learning Data Analysis |
| Cyntellect | , | Important assets acquired by Brooks Automation Feb 2012, Company dissolved May 2012 |
| Olymvax | Chengdu, China | Vaccines |
| QSV Biologics | , | Website Gone |
| American Life Science Pharmaceuticals | , | Website taken over Jun 2020 |
| Atnahs Pharmaceuticals | , | Renamed Pharmanovia |
| County Line Pharmaceuticals | , | Acquired by Alvogen, Mar 2016, $300M |
| Cormorant Pharmaceuticals | , | Acquired by BMS, Jul 2016, $95M + $425M milestones |
| , | Website taken over May 2026 | |
| Symogen | Marlow, UK | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Lineagen | , | Acquired by Bionano Genomics, Aug 2020, $9.6M |
| Lyra Therapeutics | Virtual, US | Biomedical scaffold technology |
| Monserate Biotechnology Group | , | Occasionally file business docs. Website has a 1998 copyright on one page as of Oct 2022 |
| Pall | Port Washington, NY | Filtration |
| BlackThorn Therapeutics | , | Acquired by Neumora, Oct 2021 |
| Scion NeuroStim | , | Presumed gone |
| Kent Scientific | Torrington, CT | Animal Research Equipment |
| MediciNova | La Jolla, CA | Small Molecules |
| SummerBio | , | Quit after pandemic testing no longer needed, 2021 |
| Trilogy Sciences | , | Renamed Totus Medicines, Dec 2020 |
| Lifeline Cell Technology | Frederick, MD | Primary human cells, optimized cell culture media, and cell culture reagents |
| Proa Medical | , | Business lapsed in CA 2022, boutique at old location, no employees on LI |
| Biocatalyst | , | Website down Oct 2021 - Mar 2022 |
| Biota Pharmaceuticals | , | Changed name to Aviragen Therapeutics, Apr 2016 |
| MaaT Pharma | Lyon, France | Microbiome Correction |
| Xequel Bio | Virtual, Virtual | Peptide for Injury Healing |
| Lutonix | , | Acquired by C.R. Bard, Dec 2011 |
| AccuraGen | San Jose, CA | Liquid Cancer Biopsy |
| ApoPharma | , | Seems folded into parent, Nov 2023 |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| Oxyrase | Mansfield, OH | Oxygen Removal Technology |
| Prothena | Brisbane, CA | Antibodies for neuro / immune targets |
| Hovione | Loures, Portugal | Contract Manufacturing |
| Vital Therapies | , | Reverse merged with Immunic Therapeutics, Apr 2019 |
| BioArkive | , | Website gone Jun 2022 - Oct 2022 |
| CertiRx | , | Shut down |
| Keystone Clinical Studies | , | Now part of Flourish Research |
| 490 BioTech | , | Website down Feb 2025 - Jul 2025 |
| Ankaa Therapeutics | , | no news since 2016 as of Dec 2020, residential address |
| Genfit | Cambridge, MA | Drug Discovery |
| TAI Diagnostics | , | Gone |
| Combangio | , | Acquired by Kala Pharmaceuticals, Nov 2021 |
| Optimer Pharmaceuticals | , | Acquired by Cubist Oct 2013 |
| Harpoon Therapeutics | , | Acquired by Merck, Mar 2024, $680M |
| Quanticate | Bangalore, India | Clinical Research |
| AlloOnc | , | Pie-in-the-sky startup. Giving out T shirts for donations. Gone |
| PrEP Biopharm | , | Website down Sep 2023 - Mar 2024 |
| OcyonBio | Aguadilla, PR | Contract Manufacturing |
| Lameplast Group | , | Now part of TekniPlex Healthcare |
| Plex Pharmaceuticals | , | No news 2020-2023; Acquired by Collidion, 2017 |
| DM Clinical Research | Houston, TX | Clinical Research |
| Lab Owl | , | Part of Inflexion Point |
| Profusa | Emeryville, CA | Real-time biosensors |
| Treace Medical Concepts | Ponte Vedra, FL | Bunion surgical device |
| Marman Industries | La Verne, CA | Contract Manufacturing - Plastic Devices |
| Sinorda Biomedicine | Guiyang, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Axcend | Lehi, UT | Chromatography Services |
| NIOX | Uppsala, Sweden | Asthma management device |
| Lonza | Pearland, TX | Contract Manufacturing, Development; Lab Systems, Research Products |
| Exocell | , | Acquired by Ethos Biosciences, Nov 2018 |
| Akermin | , | Closed |
| Lysogene | , | Liquidating, Jan-May 2023 |
| Viasys Healthcare | , | Acquired by Cardinal Health, May 2007, $1.5B |
| ProPharma Group | Westlake, OH | Consulting |
| BioSciencesCorp | San Ramon, CA | Biologics Services & Consulting |
| DNA Technology | , | Merged with Biosearch Technologies, 2013 |
| NTRC | , | Now Oncolines |
| Orgenesis | Germantown, MD | Autologous Cellular Conversion |
| Obsidian Therapeutics | Cambridge, MA | Cell & Gene Therapies |
| TheraCell | , | Acquired by Isto Biologics, Apr 2022 |
| Ana-Gen Technologies | , | Gone post 2001 |
| Blu Biotech | , | Website down May 2023, CEO gone |
| DDL | Irvine, CA | Device Testing |
| GenSyn Technologies | , | Website gone, Oct 2017 |
| Wavely Diagnostics | Seattle, WA | Smartphone-Based Ear Infection Diagnostic |
| Charles River Laboratories | Hyderabad, India | Research Animal Models and Preclinical Research |
| Pharmaron | Beijing, China | R&D Services |
| ENCO Pack | , | Nothing on website, 2018-Dec 2022 |
| ErVimmune | Lyon, France | Cancer Vaccines |
| LegoChem Biosciences | , | Renamed LigoChem Biosciences, May 2024 |
| Ningaloo Biosystems | Cologne, Germany | Optogenetic Bioproduction |
| Invibio | Cleveleys, UK | Implants |
| MercachemSyncom | , | Renamed Symeres, Nov 2020 |
| Torque Therapeutics | , | Merged with Cogen Immune Medicines to become Repertoire Immune Medicines, Mar 2020 |
| Semnur Pharmaceuticals | , | Merged with Scilex, Mar 2019 |
| Indena | Milan, Italy | CDMO |
| LambdaGen Therapeutics | Singapore, Singapore | Non-viral, genome insertion |
| Plexision | Pittsburgh, PA | Diagnostics |
| Microphage | , | Bankrupt Jun 2013 |
| Purna Pharmaceuticals | Puurs, Belgium | Contract services for the development and manufacturing of semi-solid, powders and liquid pharmaceutical products |
| BioSymetrics | Boston, MA | Phenomics-driven drug discovery |
| CohBar | , | Shut down, late 2023 |
| ActivX Biosciences | , | Shut down Mar 2023 |
| LiliumX | , | Renamed Valink Therapeutics, Nov 2023 |
| BioNumerik Pharmaceuticals | , | Website gone Jan 2019 |
| VB Spine | Leesburg, VA | Spinal Implants |
| Maxer Endoscopy | , | Acquired by Erbe Elektromedizin, Apr 2021 |
| NeuMoDx Molecular | , | Shut down Jun 2024; Fully acquired by Qiagen, Sep 2020 |
| , | Website down May 2025 - Dec 2025 | |
| , | Acquired by Harrow Health, Nov 2025; Spun out of Harrow Health/Imprimis Jan 2019 | |
| Ingenetix | Wien, Austria | PCR Products |
| NeoGenomics | Nashville, TN | Genetic & Diagnostic Testing |
| Solace Therapeutics | , | Shut down Sep 2022 |
| Epigenic Therapeutics | Shanghai, China | Gene Editing Therapy |
| Agenus | Lexington, MA | Biologics, Vaccines |
| Epicyte Pharmaceutical | , | Acquired by Biolex May 2004 |
| Pfizer | Sanford, NC | Small Molecules, Vaccines, Biologics |
| Ambys Medicines | , | Acquired by Cytotheryx, Feb 2023 |
| SonoThera | South SF, CA | Ultrasound-mediated nonviral gene delivery platform |
| , | Website down Oct 2025 - Jan 2026 | |
| Aro Biotherapeutics | Philadelphia, PA | Protein Scaffolds, Antisense Oligonucleotide |
| NatCure Sciences | , | Website Gone, Jan 2016 |
| Anza Therapeutics | , | Closed Feb 2009, assets bought by Aduro Biotech |
| Immunovative Therapies | , | Website down May 2023 - Dec 2023 |
| Charles River Laboratories | Kuopio, Finland | Research Animal Models and Preclinical Research |
| EndoChoice | , | Acquired by Boston Scientific, Nov 2016, $210M |
| Spark Therapeutics | , | Acquired by Roche, Dec 2019, $4.8B |
| TransThera Sciences | Nanjing, China | Small Molecules |
| Teleflex Medical | Le Faget, France | Surgical and Medical Devices |
| Somatex | Berlin, Germany | Biopsy Marker, tumor localization |
| iSonea | , | Changed name to Respiri, Dec 2015 |
| CellEctric Biosciences | Vienna, Austria | Electromagnetic cell manipulation |
| Symmetry medical | , | Acquired by Tecomet, Dec 2014 |
| Acertara Acoustic Laboratories | Longmont, CO | Ultrasound probe testing devices |
| resTORbio | , | Merged with Adicet Bio, Sep 2020 |
| United Therapeutics | Silver Spring, MD | Small Molecules, Biologics |
| Sunregen Healthcare | , | Website down Jun 2021 - Oct 2021 |
| Cali Biosciences | Shenzhen, China | 505(b)2 Drugs |
| |
Talinn, Estonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Element Science | San Francisco, CA | Wearable device to prevent cardiac death |
| Alba Bioscience | , | Took name of Quotient BioDiagnostics, May 2013 |
| Proprio | Seattle, WA | Light Field-Enabled Surgical technology |
| Artios Pharma | Cambridge, UK | DNA Damage Response Therapies |
| Synairgen | Southampton, UK | Inhaled Biologics |
| Astero Bio | , | Acquired by BioLife Solutions, Apr 2019, $8M; Bought all assets of MedCision, May 2018 |
| Allegro Ophthalmics | San Juan Capistrano, CA | Ophthalmic Small Molecules |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Delpharm | Pointe-Claire, QC | Contract Manufacturing |
| Rectify Pharmaceuticals | Boston, MA | Positive Functional Modulators disease-modifying precision therapeutics that restore ABC transporter function |
| Zai Lab | Cambridge, MA | Small Molecules |
| Inventa BioTech | , | Website gone Jun 2020, shell company |
| Seda | Manchester, UK | Pharmaceutical Development and Clinical Pharmacology |
| Bell Biosystems | , | Website down Jul 2019 - Oct 2019 |
| Zencore Biologics | Shanghai, China | Contract Manufacturing |
| Rechon Life Science | , | Ancient website Dec 2020 |
| WCG Clinical | Cary, NC | Clinical Trial Services |
| SGM Biotech | , | Acquired by Mesa Biotech, Apr 2010 |
| BioInvent International | Lund, Sweden | Antibody Drugs |
| Nihon Kohden | Shanghai, China | Medical Electronic Equipment |
| Delpharm | Evreux, France | Contract Manufacturing |
| Peptagen | , | Annual report filed with NC Apr 2014. Don’t really seem active though. Tip that they ran out of money 2012 |
| Laboratorio Elea Phoenix | Buenos Aires, Argentina | Drug Exporter |
| Berg Pharma | , | Now just Berg |
| Matritech | , | Assets bought by Matritech 2007 |
| Devgen | , | Bought by Syngenta, Sep 2012 |
| CORONIS | Athens, Greece | Clinical Studies |
| Therasonic | Paris, France | Drug Delivery to the Brain |
| Nurix Therapeutics | Brisbane, CA | Small Molecules, Protein Degradation |
| Silenseed | , | Renamed Silexion |
| Proven Process Medical Devices | , | Acquired by NextPhase, May 2021 |
| Butterfly Network | Guilford, CT | Subscription Ultrasound Device |
| Inmagene | , | Renamed Imagene, Aug 2025 |
| Cibiem | , | Shut down May 2021 |
| Teligent | , | Bankruptcy, Oct 2021, selling company off |
| CRISPR Therapeutics | Zug, Switzerland | CRISPR-Cas9 therapy |
| Adona Medical | Los Gatos, CA | Device for Heart Failure |
| Aperture Therapeutics | San Carlos , CA | Oligonucleotide therapeutics |
| Mapmygenome | Hyderabad, India | Consumer-focused genomic analysis |
| EndoSphere | , | Gone pre-2011 |
| AblaCare | , | Renamed May Health, Sep 2022 |
| Sakura Finetek | Torrance, CA | Automated instruments, consumables, and reagents for anatomic pathology |
| Bilhi Genetics | , | Website down Oct 2024 - Feb 2025, closed on Google |
| Radionetics Oncology | San Diego, CA | Radiopharmaceuticals |
| Contextual Genomics | , | Renamed Canexia Health, Jul 2020 |
| GeneMed Biotechnologies | Torrance, CA | Molecular Diagnostics, Tissue based diagnostics |
| Endotelix | Geneva, Switzerland | Diagnostics, Research reagents for Antiphospholipid Syndrome |
| Bioincept | , | 20+ years, no products, no LI page, unfinished website Nov 2023 |
| CellVec | Singapore, Singapore | Gene therapy CDMO, cGMP license to manufacture Viral vectors |
| Cellective BioTherapy | , | No active employees on LI, nothing much happened 2015-2023, listed execs on website not scientific |
| MPI Research | , | Acquired by Charles River Laboratories, Apr 2018, $800M |
| Bio Elpida | , | Acquired by Sartorius, Dec 2022 |
| JD Bioscience | Seoul, Korea | Small Molecules |
| RedHill Biopharma | Raleigh, NC | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Third Harmonic Bio | , | Liquidation, Apr 2025 |
| Daktari Diagnostics | , | Gone 2017 |
| Turning Point Therapeutics | , | Acquired by BMS, Aug 2022, $4.1B; fka TP Therapeutics |
| Walking Fish Therapeutics | , | Shut down May 2024 |
| NxThera | , | Acquired by Boston Scientific, Apr 2018, $306M + $100M milestones |
| , | Acquired by BioCryst, Jan 2026, $700M; fka Catabasis Pharmaceuticals | |
| Fosun Pharma | Zurich, Switzerland | Small molecules, diagnostics, traditional |
| Indivumed Therapeutics | Hamburg, Germany | Biospecimens |
| Renerva | Pittsburgh, PA | Implantable technologies to improve the outcome of peripheral nerve repair procedures |
| Peplin | , | Acquired by Leo Pharma 2009 |
| Best Vascular Novoste | , | Now Novoste |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
 |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Scidera Genomics | , | Bought by Neogen, Jan 2013 |
| Diamed | , | Bought by Bio-rad |
| CellPly | Bologna, Italy | Personalized cancer treatment |
| LAXAI | Hyderabad, India | Pharma, Biotech CDMO |
| Delpharm | L'aigle, France | Contract Manufacturing |
| Genomas | , | Website gone May 2020 |
| Aeris Therapeutics | , | Assets auctioned, Acquired by Pulmonx Jan 2015 |
| Altasciences | Montréal, QC | Contract Research |
| HeartBeat.bio | Vienna, Austria | Heart Organoid |
| Delve Bio | Boston, MA | Metagenomic NGS Diagnostics |
| Veristat | Basel, Switzerland | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Antikor Biopharma | Stevenage, UK | ADC technology |
| Neurodyn | , | Renamed AlphaCognition, Feb 2020 |
| Novadip Biosciences | Mont-Saint-Guibert , Belgium | Personalized, Stem-Cell Based Regenerative Medicine |
| Siemens Healthineers | Malvern, PA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Synergistix | Sunrise, FL | CRM software |
| Intradigm | , | Merged with Silence Therapeutics 2009 |
| PCI Pharma Services | Madison, WI | Contract Manufacturing, Services |
| CleanNA | Waddinxveen , Netherlands | Nucleic Acid Extraction Kits and Automation Systems |
| Athersys | Cleveland, OH | Stem Cell Treatments |
| The Ritedose Corporation | Columbia, SC | Contract manufacturing of small fill volume pharmaceutical unit dose sterile and non-sterile liquids |
| Speedel Pharma | , | Bought by Novartis, Jul 2008, $880M |
| Clinical Data | , | Bought by Forest Labs Feb 2011 |
| Creative Diagnostics | Shirley, NY | Antibodies, Diagnostic components, viral antigens, etc. |
| Premas Biotech | Gurugram, India | Contract Research, Development & Manufacturing |
| 360biolabs | Melbourne, Australia | Contract service provider bringing together virology and immunology in a quality-assured environment |
| Biotecx Laboratories | , | Website not updated since 2007. AOL email |
| AddexBio | San Diego, CA | Reagents, Cells, Research Tools |
| Alcanza Clinical Research | Methuen, MA | Clinical Sites |
| 4SR Biosciences | , | Merged with hC Bioscience, Jan 2023 |
| Onera Health | Eindhoven, Netherlands | Sleep Diagnostics & Monitoring |
| Verrica Pharmaceuticals | West Chester, PA | Topical therapies |
| New World Medical | Rancho Cucamonga, CA | Surgical Tools |
| Cambrex | Longmont, CO | Small Molecules Research, Development & Manufacturing Services |
| Mosaic Therapeutics | Cambridge, UK | Combination Therapies for Oncology |
| Celladon | , | Merged into Eiger Bio, Mar 2016 |
| Biomay | Vienna, Austria | Contract Biologics & Related |
| Bioniche Pharma | , | Acquired by Mylan, Sep 2010, $550M |
| EpicGenetics | , | Seems gone Jan 2024 |
| Abt Bio-Pharma Solutions | , | Acquired by United Biosource, May 2010 |
| Zipline Medical | , | Acquired by Stryker, Jul 2018, $9M |
| Mera Pharmaceuticals | , | Bought by a karate business, Aug 2012, presumably for ticker |
| PreClinOmics | , | Acquired by Crown Bioscience, Mar 2016 |
| NeuroTherm | , | Bought by St Jude Medical Aug 2014, $200M |
| Chargepoint Technology | Liverpool, UK | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| Global Pharma Tek | Toronto, ON | Contract Research, Clinical Research, Consulting |
| IV Diagnostics | , | Website down Sep 2023 - Mar 2024, LI gone Dec 2023 |
| Alera Labs | Durham, NC | Contract Research & Services |
| Cellares | San Francisco, CA | Cell Therapy Manufacturing Technology |
| Adthera Bio | Birmingham, UK | Cell Therapy CDMO |
| Companion Medical | , | Acquired by Medtronic, Aug 2020 |
| Y-mAbs Therapeutics | New York, NY | Antibody Therapies for Oncology |
| Körber | Hamburg, Germany | Production Monitoring Software |
| Kadimastem | Ness Ziona, Israel | Stem cell therapeutics |
| Sedia Biosciences | Beaverton , OR | Diagnostics & Sampling |
| CoMentis | , | Fka Athenagen, site gone Oct 2017 |
| Genosity | , | Bought by Invitae, Apr 2021, $200M |
| Signature Therapeutics | , | Merged into Ensysce Biosciences, Dec 2015 |
| Ancora Pharmaceuticals | , | Assets Acquired by Corden Pharm, Oct 2013 |
| Engitix | London, UK | Human Organ Decellularization Technology |
| Genection | , | InVivoScribe Subsidiary. Integrated as of Apr 2015 |
| preclinics | Eystrup, Germany | Contract Research |
| ACROBiosystems | Chessington, UK | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Movetis | , | Acquired by Shire, Aug 2010 |
| Rani Therapeutics | San Jose, CA | Orally delivered Biologics |
| Cirsium Biosciences | San Diego, CA | Plant-grown Gene Therapy |
| Adaptimmune Therapeutics | Philadelphia, PA | T Cell Cancer Therapy |
| Samsung Biologics | Incheon, Korea | Contract Biologics Manufacturing |
| Cole-Parmer | Shanghai, China | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| Demetrix | , | No employees on LI Oct 2024; Website down Aug 2024 - Oct 2024 |
| Orexo | Morristown, NJ | Improved specialty pharmaceuticals and treatments for new areas of use |
| eMed Technologies | El Dorado Hills, CA | Infusion System |
| Siegfried | Hal Far, Malta | Contract Drug Manufacturing, APIS, Development |
| RaySearch Laboratories | Hasselt, Belgium | Cancer Research Software |
| Celek Pharmaceuticals | , | Dissolved Dec 2013 |
| Shalby Advanced Technologies | El Dorado Hills, CA | Orthopedic Implants |
| ABAC Therapeutics | , | Website down Dec 2024 - May 2025 |
| IMBiotechnologies | Edmonton, AB | Embolotherapy devices |
| Alan Laboratories | , | Website gone, Jan 2019 |
| Vyne Therapeutics | Ness Ziona, Israel | Small Molecule |
| Ichor Medical Systems | San Diego, CA | Enhanced Delivery of Gene Therapy |
| Replicate Bioscience | San Diego, CA | Preventing oncology drug resistance |
| Biohit | Helsinki, Finland | Diagnostics |
| ObvioHealth | New York, NY | Clinical Study Software |
| Scibase | Berlin, Germany | Complementary Information for Melanoma Detection |
| Irazu Oncology | Baltimore, MD | Outer membrane vesicle technology |
| VGYAAN Pharmaceuticals | Skillman, NJ | Specialty Pharmaceuticals |
| Alydia Health | , | Acquired by Organon Jun 2021; fka InPress Technologies |
| Invea Therapeutics | Guilford, CT | AI Drug Discovery to Target Gut-Brain Axis |
| Recipharm | Odivelas, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Taxus Cardium Pharmaceuticals | , | Changed name to Gene Biotherapeutics, new entity named Taxus Cardum sprung up to manage umbrella companies? |
| Crown Bioscience | Beijing, China | Drug Development |
| Euprotein | , | Acquired by Meridian Bioscience, Apr 2022 |
| Pharmavene | , | Acquired by Shire, Mar 1997 |
| Chromtech | Apple Valley, MN | Chromatography Products |
| LinKinVax | , | Rebranded as EnnoDC |
| Rad AI | San Francisco, CA | Radiology Software |
| Nephron Pharmaceuticals | West Columbia, SC | Generic Respiratory Medications & Contract Manufacturing |
| Norgine | Madrid, Spain | Specialty Pharma |
| Cytoskeleton | Denver, CO | Research Products |
| BetaStem Therapeutics | , | Gone as of Oct 2016, likely much sooner, Unknown fate. |
| Carl Zeiss Meditec | Dublin, CA | Medical Devices |
| Curasan | Wake Forest, NC | Dental Bone Grafts |
| Acino | Aesch, Switzerland | Novel drug delivery formulations |
| Microlin Bio | , | Presumed gone, website gone Jan 2019 |
| Sonavex | Baltimore, MD | Ultrasound |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Calibra Medical | , | Acquired by JNJ 2012 |
| Amzell | , | Website down Jul 2021 - Dec 2021 |
| Brooks Life Sciences | , | Renamed Azenta Life Sciences, Sep 2021 |
| EuMederis Pharmaceuticals | , | One person, no news 2013 - Jun 2023 |
| Key Tech | Baltimore, MD | Medical Device Consultants |
| Advanced Clinical | Maitland, FL | Clinical Research Organization |
| Transcenta Therapeutics | Suzhou, China | Antibody Therapeutics |
| Privo Technologies | Peabody, MA | Nano-engineered treatments |
| Elona Pharmaceuticals | , | Gone |
| Butterworth Labs | Middlesex, UK | Analytical Chemistry |
| Stuart Therapeutics | Stuart, FL | Treatments for chronic ophthalmology conditions |
| Mirus Bio | Madison, WI | Transfection Reagents, Biotech Services |
| MGI Tech | Shenzhen, China | Sequencing instruments, reagents, and related products |
| Vanadis Laboratories | , | Gone 2018 |
| Ondine Biomedical | Vancouver, BC | Anti-Infectives, Photodisinfection |
| Empyrean Neuroscience | Cambridge, UK | Small Molecules Derived from Plants and Fungi |
| Neotropix | , | No news since 2011, no employees on LinkedIn with pictures. Doubt this company is active |
| FineHeart | Pessac, France | Heart Failure Device |
| Impact Biologicals | , | Ludicrously old website, Nov 2019 |
| Etiome | Cambridge, MA | AI platform to forecast disease progression in patients |
| Lusis | Hayward, CA | Diagnostics |
| Aresus Pharma | , | Seems folded in to Dermago |
| Sortis Pharma | Hyderabad, India | Contract Services |
| Roche | Rotkreuz, Switzerland | Diagnostics |
| Accriva Diagnostics | , | Acquired by Werfen/Instrumentation Laboratory, Jan 2017; fka ITC |
| Tepha Medical Devices | , | Acquired by BD, Jul 2021 |
| Gene Techno Science | , | Renamed Kidswell Bio |
| Blue Oak Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Novaliq | Cambridge, MA | Drug Delivery |
| Scios Nova | , | Changed name to Scios, Mar 1992 |
| Santarus | , | Acquired by Salix Pharmaceuticals, Jan 2014 |
| Caris Life Sciences | Basel, Switzerland | Diagnostics |
| ARIAD Gene Therapeutics | , | Merged into ARIAD, Sep 2008 |
| Solway Pharmaceuticals | , | Nothing out there but a facebook page |
| Brightflow Medical | Paris, France | Heart Failure Device |
| Bayer | Barcelona, Spain | Small Molecules |
| Hemab Therapeutics | Copenhagen, Denmark | Bleeding Disorder Treatments |
| BioAesthetics | , | Website maintenance, Sep 2024 - Aug 2025 |
| Oncurious | , | Closed according to Google Dec 2022; Website down Sep 2022 - Dec 2022 |
| Monopteros Therapeutics | , | Business Filings late Mar 2024; Website down Mar 2024 - Jul 2024; Residential address, Jul 2022 |
| Vico Therapeutics | Leiden, Netherlands | Oligonucleotide based RNA modulating therapeutics |
| Syrinx Bioanalytics | , | Acquired by Senexa Life Science, May 2022 |
| Pfizer | Lake Forest, IL | Sterile Injectables |
| NovoBiotic Pharmaceuticals | Cambridge, MA | Small Molecules |
| Rezolute | Bend, OR | Biologics |
| Middle Peak Medical | , | Acquired by Symetis, technology moved to Polares Medical |
| Iota Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| HCW Biologics | Miramar, FL | Immunotherapy |
| Vistagen Therapeutics | South SF, CA | Stem Cell Technology |
| Kestra Medical Technologies | Kirkland, WA | Wearable Medical Devices |
| bioMerieux | Saint-Laurent, QC | Diagnostics |
| Human Genome Sciences | , | Bought by GSK |
| System1 Biosciences | , | Renamed Herophilus, Jan 2021 |
| Cytek Biosciences | Fremont, CA | Flow Cytometers |
| Draxis Pharma | , | Bought by Jubilant 2008 |
| GenoImmune | , | |
| Titan Spine | , | Bought by Medtronic, Jun 2019 |
| Armada Pharmaceuticals | , | Renamed Formation Biologics |
| Apellis Pharmaceuticals | San Francisco, CA | Cyclic peptide analog |
| Daisy Genomics | Carlsbad, CA | Long-read sequencing platform |
| Worldwide Clinical Trials | Bucharest, Romania | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Astellas | Killorglin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| abiliLife | , | Website gone Dec 2023 - Feb 2024 |
| , | Renamed Peritia, Jan 2026 | |
| Brammer Bio | , | Bought by Thermo Fisher, May 2019, $1.7B |
| SolaranRx | , | Website taken over |
| Parexel | Newton, MA | Clinical Research |
| Redwood Scientific | , | Website gone Nov 2018, Had FTC problems |
| , | Acquired by Ligthouse Lab Services | |
| THERAMetrics | , | Acquired Relief Therapeutics, Jun 2016, took name |
| Comprehend Systems | , | Acquired by Saama Technologies, Aug 2019 |
| Teleflex Medical | Mexico City, Mexico | Surgical and Medical Devices |
| Curium Pharma | Noblesville, IN | Nuclear Diagnostics & Medicine |
| , | Renamed Terrestrial Bio, Mar 2026 | |
| Nervive | , | Website down Nov 2023 - Mar 2024 |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| ESI Bio | , | Joined with Hepregen to become Ascendance Biotechnology, Nov 2015 |
| Califia Bio | , | Shut down May 2020 |
| Kiji Therapeutics | Paris, France | iPSC-MSC |
| Biotez | , | Acquired by BBI Solutions, Jan 2022 |
| Lupagen | Dallas, TX | Improved Cell & Gene Therapy Production |
| GeniPhys | Indianapolis, IN | Collagen for Tissues Regeneration |
| Dolomite Bio | , | Acquired by Unchained Labs, Jul 2023 |
| Unither Pharmaceuticals | Gannat, France | CDMO |
| LipoScience | , | Bought by LabCorp, Nov 2014, $85.3M |
| Bayer | Grenzach, Germany | Biotech / Pharma / Chemical Giant |
 |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Scailyte | Basel, Switzerland | AI interpretation of Single Cell Data |
| Diapharm Analytics | Münster, Germany | Pharma, Life Sciences Consulting |
| |
Sisseln, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Inova Diagnostics | , | Acquired by Werfen, 2008 |
| Stemgent | , | Acquired by ReproCELL, Sep 2014 |
| Innovent Biologics | Jiangsu, China | Monoclonal Antibodies, Biosimilars |
| DiaCarta | Nanjing, China | Molecular Diagnostics Tests |
| Bifrost Biosystems | Berkeley, CA | Optical Pooled Screening Technology |
| Abogen | Suzhou, China | mRNA |
| Quartzy | Hayward, CA | Lab Management Software |
| Biotox Sciences | , | Renamed BTS Research |
| Glycostem | Oss, Netherlands | Cellular Immunotherapy, Growth Medium |
| Nova Therapeutics | Mississauga, ON | Cancer Treatments |
| PreludeDx | Laguna Hills, CA | Breast Cancer Diagnostic Platform |
| Sanofi | Geel, Belgium | Small Molecules, Biologics |
| White Biotech Solutions | , | Shut Down 2019 |
| Contraria Biotech | , | Reported closed Apr 2025; Website down Feb 2025 - Mar 2025; fka AchilleS Vaccines |
| CoCo Therapeutics | , | Dissolved Apr 2016 |
| 89bio | San Francisco, CA | Liver Treatments |
| Luna Innovations | Roanoke, VA | Sensors and Systems |
| Synaptis Therapeutics | , | Doesn't seem active Aug 2022 |
| OrciMed Life Sciences | Hyderabad, India | Clinical Services |
| Abcam | Cambridge, UK | Antibodies |
| NeuroWave Systems | Beachwood, OH | EEG |
| Viela Bio | , | Acquired by Horizon Therapeutics, Mar 2021, $3B; MedImmune spinout |
| Miller Technical Services | Plymouth, MI | Medical Device Manufacturing |
| CMIC | Tokyo, Japan | Pharmaceutical Contract Work |
| OpenClinica | Needham, MA | Clinical Study Software |
| Technoclone | Vienna, Austria | Diagnostics for blood clotting and haemostasias |
| Innovative Health Solutions | , | Renamed Neuraxis, May 2022 |
| Bristol Myers Squibb | Brisbane, CA | Small Molecules, Biologics |
| Ovation.io | Portland, ME | LIMS |
| NeuroproteXeon | , | Gone 2021 |
| ALung Technologies | , | Acquired by LivaNova, Jul 2022 |
| VentiRx Pharmaceuticals | , | Apparently acquired by Celgene |
| Eclipsebio | San Diego, CA | RNA Products & Services |
| Stira Pharmaceuticals | Fairfield, NJ | Product Development, Analytical R&D |
| Arnatar Therapeutics | San Diego, CA | RNA-based Medicines |
| Escient Pharmaceuticals | San Diego, CA | GPCR-targeted Drugs |
| Ractigen Therapeutics | Nantong, China | Small activating RNA |
| Baxano Surgical | , | Bankrupt, 2014, product bought by group that named themselves TranS1 |
| Inhibitex | , | Acquired by BMS 2012, $2.5B |
| Allarity Therapeutics | Hørsholm, Denmark | Cancer Treatments with Companion Diagnostics |
| Cellnovo | , | Bankrupt, Jul 2019 |
| Rinat | , | Bought by Pfizer 2006 |
| AB Diagnostic Systems | Berlin, Germany | Clinical Diagnostics |
| NanoCor Therapeutics | , | Seems gone. Website gone Sep 2015. 2 employees on Linkedin. Spun out from Asklepios |
| Genus Oncology | , | Website down Jul 2022; Not registered business in MA, Dec 2019 |
| CompleGen | , | Shut down Aug 2021 |
| Acertara Acoustic Laboratories | Daejeon, Korea | Ultrasound probe testing devices |
| Enterin | , | Website taken over Feb 2025 |
| Girindus | , | Sold by Solvay to Nitto Denko Avecia Jan 2013 |
| Align Pharmaceuticals | , | Acquired by Cyclacel, Oct 2007 |
| pro-Actina | , | Website down Dec 2021 - Apr 2022 |
| COBIK | Ajdovščina, Slovenia | Contract Work, Drug Discovery |
| Multiplex Biosciences | , | Merged with Rules-Based Medicine, Nov 2006 |
| BrYet Health | , | Website down Oct 2022 - Mar 2023 |
| Alma Bio Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Silony Spine | Frauenfeld, Switzerland | Implants, Instruments |
| , | Website down Jan 2026 - May 2026 | |
| Celonic | Basel, Switzerland | Biologics Contract Work |
| ROKIT | Seoul, Korea | Organ Regeneration |
| EXINI Diagnostics | Lund, Sweden | Diagnostic Devices |
| Rentschler Biopharma | Laupheim, Germany | Biologics CMO |
| BiaCure Therapies | Milwaukee, WI | High-Frequency Energy Technology for the Treatment of Onychomycosis |
| Elevate Movement | Carlsbad, CA | External Orthopedics Support Devices |
| Karuna Therapeutics | , | Acquired by BMS, Mar 2024, $12.7B |
| GIVAX | Boston, MA | GI Vaccines |
| PeptiMimesis | , | No news 2017-2024, Employees all gone Jul 2024 |
| CC-Pharming | , | Website down Aug 2023 - Dec 2023 |
| VytronUS | , | Shut down Mar 2020 |
| Laboratoires Robert and Carrière | , | Merged with Laboratoires Dausse in 1970 to become Synthélabo |
| Zyla Life Sciences | , | Merged into Assertio, May 2020 |
| Medtronic | Raleigh, NC | Imaging, Medical Devices |
| Karykion | , | Website outdated, doesn't seem serious |
| Geneffects | , | Shut down Feb 2020 |
| Attoplex | Hanam-si, Korea | Molecular Diagnostics |
| 4immune Therapeutics | Westwood, MA | CAL / CAR T Cell Therapy |
| Mach5 Therapeutics | Atlanta, GA | Gene therapies and advanced biologics |
| ContraVir Pharmaceuticals | , | Renamed Hepion Pharmaceuticals, Jul 2019 |
| , | Renamed Tangram Therapeutics, Oct 2025 | |
| Attwill Medical Solutions | Lodi , WI | Vascular Access Technologies |
| Embecta | Parsippany, NJ | Diabetes Care |
 |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Immunocore | Abingdon, UK | T Cell Receptor Fragment Therapies |
| Viant Medical | Barreal de Heredia, Costa Rica | Contract Medical Devices |
| MediPrint Ophthalmics | San Diego, CA | Digital Printing on Contact Lenses for Drug Delivery |
| Celata Therapeutics | , | Renamed Pepper Bio, Oct 2021 |
| Texcell | Evry, France | Contract Research |
| Anvil Biosciences | , | Assets acquired 2017-2018 |
| Mast Therapeutics | , | Bought by Savara for its public shell, Jan 2017 |
| Nectar Life Sciences | Chandigarh, India | API Manufacturing |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Arsenal Biosciences | South SF, CA | Cancer Treatments |
| Magic Lifescience | Mountain View, CA | POC Molecular Diagnostics |
| Coripharma | Hafnarfjordur, Iceland | Contract Generic Manufacturing |
| HUB Organoids | Utrecht, Netherlands | Organoids, Services |
| AgeX Therapeutics | , | Merged with Serina Therapeutics, Mar 2024 |
| Laboratorio Reig Jofre | Malmö, Sweden | Pharma manufacturing (antibiotics/injectable |
| Beactica Therapeutics | Uppsala, Sweden | Fragment-based drug discovery platform |
| BioGrasp | , | New website coming soon May 2020 - May 2021 |
| Cephalon | , | Acquired by Teva, Oct 2011, $6.8B |
| Laguna Pharmaceuticals | , | Shut down, Dec 2015; fka ChanRx |
| Pharma Tech Industries | Royston, GA | Contract Manufacturing |
| Odyssey Therapeutics (2) | Frankfurt , Germany | Small Molecules, Biologics |
| Fosun Pharma | Mumbai, India | Small molecules, diagnostics, traditional |
| Foundation Medicine | Boston, MA | Diagnostic Assay |
| California Biotechnology | , | Renamed Scios, Mar 1992 |
| Neteera Technologies | Jerusalem, Israel | Contactless Remote Patient Monitoring |
| Tavros Therapeutics | , | Acquired by Vividion Therapeutics, Jan 2025 |
| Advanced Softgel | , | Not FDA registered, Feb 2022, probably all nutraceuticals |
| Tegra Medical | Dartmouth, MA | Contract Medical Device Manufacturer |
| Arrevus | , | Acquired by Aceragen, Nov 2021 |
| Biscayne Neurotherapeutics | , | Acquired by Supernus, Oct 2018, $15M + $168M milestones |
| Panoptes Pharma | , | Acquired by EyeGate Pharmaceuticals, Jan 2021 |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Agios Pharmaceuticals | Cambridge, MA | Small Molecules |
| Seismic Therapeutic | Watertown, MA | Bispecific therapeutic antibodies |
| Millipore | Burlington, MA | Purification, Analytic Biologics, Discovery |
| Sellas Life Sciences Group | New York, NY | Cancer Immunotherapies |
| Applied BioCode | Santa Fe Springs, CA | Bar-coded Magnetic Beads, Assays, Multiplexed Systems |
| Bio2 Technologies | , | Rebranded as Novum Medical, 2021 |
| Oticon | Somerset, NJ | Hearing Aids |
| Coho Therapeutics | , | Website gone Feb 2023; No info, Nov 2021 - Dec 2021 |
| Novonesis | Salem, VA | Enzymes, Biologic Reagents |
| Flownamics | Madison, WI | Automated Sampling |
| Jacobio Pharmaceuticals | Beijing, China | Small Molecules? |
| NovAliX | Strasbourg, France | Small Molecule Discovery Services |
| Medical Acoustics | , | Website down May 2020 - Dec 2020 |
| Unither Pharmaceuticals | Le Haillan, France | CDMO |
| Alectos Therapeutics | Burnaby, BC | Small Molecules |
| Aisa Pharma | Boston, MA | Raynaud's Treatment |
| Edwards Lifesciences | Irvine, CA | Medical Devices |
| Structure Medical | Naples, FL | Precision Implant Manufacturing |
| SeaView Research | , | Acquired by Quotient Clinical, Feb 2017 |
| HeadSense Medical | , | Founder left Dec 2017, Site gone Apr 2018 |
| MAPS PBC | , | Renamed Lykos Therapeutics, Jan 2024 |
| Hookipa Biotech | , | Now Hookipa Pharma |
| Wockhardt | Wrexham, UK | Generics, Contract Manufacturing |
| Oncodisc | , | Acquired by Veris Health, Jun 2021 |
| Xcellon Biologics | North Bethesda, MD | Complex Biologics CDMO |
| Xcorporeal | , | Agreed to be acquired, but uncertain if it happened |
| Integral BioSystems | Bedford, MA | Drug Delivery Services |
| Tecnimede | Lisbon, Portugal | Generics |
| Straumann | Basel, Switzerland | Dental Implants and Regeneration |
| Carrick Therapeutics | Dublin, Ireland | Small Molecules |
| Asha Pharma | San Diego, CA | Solid state crystallization services |
| kez.biosolutions | Potsdam-Golm, Germany | Polyketide Biosynthesis Outsourcing |
| Poniard Pharmaceuticals | , | Was a shell company being acquired by Allozyne to get listed. Called off Dec 2011. |
| Advanz Pharma | London, UK | Specialty Generics |
| Ifyber | Ithaca, NY | Contract Research - Device & Pharma |
| X-in8 Biologicals | , | No real employees, website under construction perpetually |
| Accellacare | Salisbury, NC | Clinical Research |
| Hemmo Pharmaceuticals | , | Acquired by Piramal, Apr 2021, $106M + Milestones |
| , | Pivoted to crypto Nov 2025; Formed by combination of HealthCare Pharmaceuticals & GITR, Jan 2016 | |
| Tarpon Biosystems | , | Gone by 2017 |
| Formac Pharmaceuticals | , | Tech licensed exclusively by W.R. Grace, Oct 2017 |
| Biomatik | Kitchener , ON | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Omnis Pharmaceuticals | , | Merged with Magnis Therapeutics, Mar 2016, became Vyriad |
| Enteric Medical | , | Bought by Boston Scientific, Jun 2002, $300M |
| Genecare | , | Gone |
| GlobeStar Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Analogic | Saint-Laurent, QC | Medical Imaging |
| Rubhu Biologics | Athens, GA | Cell Therapy Services |
| Becton Dickinson | Canaan, CT | Various medical devices and health products |
| Aspen Pharmacare | Gqerberha, South Africa | Small Molecules |
| Imalux | , | Ceased Operations, Apr 2014 |
| iQ Biosciences | Alameda, CA | Drug Discovery Services |
| Medicure | Princeton, NJ | Small Molecule |
| Almac | Souderton, PA | Pharmaceutical Services |
| CombiGene | , | Stopped research Jan 2025 |
| KSQ Therapeutics | Lexington, MA | CRISPR-based drug discovery |
| GliaCure | , | Website down Sep 2022 - Feb 2023 |
| Abbratech | Branford, CT | Antibody Discovery Platform |
| Amuza | San Diego, CA | Neuroscience Research Equipment |
| California Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Micregen | Reading, UK | Mesenchymal Stem Cell-derived Secretomes |
| Daiichi Sankyo | Munich, Germany | Small Molecules |
| Arteriocyte | , | Merged with ISTA Technologies to become ISTO Biologics, Oct 2016 |
| BrainSpace | Bothell, WA | Automated cerebrospinal fluid manager |
| DNAmito | , | Website down Jul 2021 - Dec 2021 |
| Genable Technologies | , | Bought by Spark Therapeutics, Mar 2016, $15M |
| Profound Medical | Mississauga, ON | Real-time MRI |
| Ibex Technologies | , | Acquired by BBI Solutions, Apr 2024 |
| Metys Pharmaceuticals | , | Acquired by Novaremed, Sep 2021 |
| Exothera | Jumet, Belgium | Viral vector CDMO |
| Koelis | Auvergne-Rhône-Alpes, France | Prostate Biopsy System |
| Delos Pharmaceuticals | , | Renamed Aeovian Pharmaceuticals, Sep 2019 |
| PharmaLex | Karlsruhe, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Abselion | Cambridge, MA | Biologics Quantification |
| , | Website down Oct 2025 - Nov 2025; No business filings Feb 2022 - Dec 2025 | |
| Celltech | , | Acquired by UCB, May 2004, $2.7B |
| Epify | , | Website down Mar 2023 - Sep 2023 |
| Triangle Insights Group | Durham, NC | Consulting |
| Versatope Therapeutics | Lowell, MA | Exosomes derived from probiotics |
| RS Medical | Vancouver, WA | Medical Devices |
| Sequana Medical | Sint-Denijs-Westrem, Belgium | Implantable pump systems |
| Sanbor Medical | Allentown, PA | Medical device manufacturing |
| Cerebral Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Regulome | , | Gone 2006 |
| Genefirst | Oxford, UK | Cancer, HPV, Respiratory Screening |
| Rapid Micro Biosystems | Munich, Germany | Microbial Analysis |
| Glycobia | , | Website Gone, Aug 2017, hired someone Feb 2018 |
| RhoVac | , | Reverse Merged with Chosa, Jan 2023 |
| JCL Bioassay | , | Renamed CMIC |
| Salubris Biotherapeutics | Gaithersburg, MD | Biologics |
| Goldpoint Clinical Research | , | Website gone, employees gone |
| , | Website down Sep 2025 - Dec 2025 | |
| CTL Amedica | Carrollton, TX | Cervical, Lumbar Implants |
| Acerand Therapeutics | Shanghai, China | Oral Small Molecules |
| Artivion | Kennesaw, GA | Tissues, surgical adhesives, additional devices |
| Brain Sentinel | , | Website down Jul 2022; CSO left Mar 2020, still on website Aug 2020 |
| Amira Medical | , | Acquired by Roche, Nov 2001 |
| CF PharmTech | Wuxi, China | Specialty Respiratory Pharmaceuticals |
| Medical Manufacturing Technologies | Charolette, NC | Medical Device Manufacturing |
| Oxford BioTherapeutics | Basel, Switzerland | Antibody Therapies |
| Achelios Therapeutics | Durham, NC | Topical small molecules |
| Red Glead Discovery | Lund, Sweden | Drug Discovery Services |
| CryoVascular | , | Bought by Boston Scientific, 2005 |
| AnaSpec | Fremont, CA | Peptides, Antibodies, Reagents |
| Cotinga Pharmaceuticals | , | Website for sale Feb 2021; fka Critical Outcome Technologies |
| OncoSec Medical | , | Chapter 7 Bankruptcy, June 2023 |
| ReWalk Robotics | , | Renamed Lifeward, Jan 2024 |
| , | Website down Aug 2025 - Jan 2026 | |
| Lupeng Pharmaceutical | Guangzhou, China | Small molecule drugs: BTK inhibitors, Bcl-2/Bcl-xL Inhibitors, Targeted Protein Degraders |
| SparingVision | Boston, MA | Retinal Gene Therapy Treatments |
| BioStorage Technologies | , | Acquired by Brooks Life Sciences, Nov 2015 |
| West Pharma | Horsens, Denmark | Pharmaceutical Supplier |
| Haplogen | , | Website down Oct 2021 - Mar 2022 |
| Percivia | , | Shut Down 2012 |
| Medipure Pharmaceuticals | , | Bankrupt, May 2022 |
| Aletheon Pharmaceuticals | , | Closed Sep 2007 |
| Capstone Therapeutics | , | Virtual/Shell Company since about 2010 |
| imarc | , | Acquired by Avania, Jun 2021 |
| Genentech | Hillsboro, OR | Small Molecules, Biologics |
| UniXell | Shanghai, China | Cell Therapy |
| Coherex Medical | , | Acquired by Biosense Webster, Nov 2015 |
| , | Website down Jul 2025 - Nov 2025 | |
| Beeken Biomedical | Newton, MA | Hemostasis Products |
| TEI Biosciences | , | Bought by Integra Life Sciences, Jun 2015 |
| Sicor Biotech | , | Bought by Teva 2004 |
| Fixx Pharmaceuticals | , | Website down Oct 2022, never registered as a business in Nevada |
| Flow Contract Site Laboratory | Bothell, WA | Flow Cytometry |
| InnoCore Pharmaceuticals | Groningen, Netherlands | Polymer Based Biodegradable Drug Delivery Technologies |
| , | Renamed Orvida Pharma, Apr 2026 | |
| Remix Therapeutics | Watertown, MA | Small molecule therapies designed to reprogram RNA processing |
| Innogen Pharmaceutical | , | Website gone Feb 2024 |
| Ardian | , | Acquired by Medtronic, Nov 2010, $800M |
| RPS Diagnostics | , | Assets acquired by Quidel, May 2017, $14M, shell merged into Lumos Diagnostics, May 2019 |
| Achira Labs | Bengaluru, India | Microfluidics-based medical diagnostics |
| Elucigene Diagnostics | , | Bought by Yourgene Health, Apr 2019 |
| Sandstone Diagnostics | , | Assets acquired by Labcorp |
| Breathomix | Leiden, Netherlands | Breath Analysis for Diagnosis |
| Clinitude | Hasselt, Belgium | Clinical Consulting |
| 92Bio | Hayward, CA | Design of multispecific biologics for the treatment of cancer |
| Freudenberg Medical | Baldwin Park, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| The RND Group | Indianapolis, IN | Medical Device Software |
| Augelux Therapeutics | Wuhan, China | AAV-Based Optogenetic Gene Therapies for Ocular Diseases |
| Ganymed Pharmaceuticals | , | Bought by Astellas, Dec 2016, $1.4B |
| Nano Science | , | Acquired by EAG, 2006 |
| Prosonix | , | Bought by Circassia, Jun 2015, $158M |
| Epsilon-3 Bio | , | Shutting down Nov 2020 |
| Praedicare | , | Website down Jan 2025 - Jul 2025 |
| Recipharm | Mannheim, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Perrigo | Allegan, MI | Small Molecule Generics, Consumer Healthcare |
| Twin City Bio | , | Renamed ProKidney, Dec 2020 |
| Hematologics | Seattle, WA | Contract molecular analysis studies |
| Ergomed | Frankfurt, Germany | Clinical Research |
| AlloVir | , | Acquired by Kolaris Therapeutics, Nov 2024 |
| Cambridge Research Biochemicals | , | Acquired by Biosynth, May 2023 |
| Hovione | Mumbai, India | Contract Manufacturing |
| Norwich Laboratories | , | Subsumed into parent Alvogen |
| Spinal Kinetics | , | Acquired by Orthofix, Mar 2018, $105M |
| Theorem Clinical Research | , | Bought by Chiltern, Sep 2015 |
| Mestastop Solutions | Bangalore, India | Oncology Discovery & Repurposing |
| Cell Essentials | , | Business filings late, Sep 2023 - Aug 2025 |
| Ocular Therapeutix | Bedford, MA | Sustained ophthalmic therapies with proprietary tailored hydrogels |
| Hercon Pharmaceuticals | , | Acquired by Zydus Cadila, 2019 |
| CPR Pharma | , | Split into Agilex Biolabs & Avance Clinical, Jan 2019 |
| ACRC Trials | , | Website down Mar 2025 - Aug 2025 |
| RaySearch Laboratories | Paris, France | Cancer Research Software |
| Quiet Therapeutics | , | Everyone seems gone Jan 2022 |
| OrthoData | , | Renamed Intellirod Spine |
| Clasp Therapeutics | Rockville, MD | Antibody-like T Cell Engagers |
| Sun Pharmaceuticals | Mumbai, India | Generic Small Molecules, APIs |
| Genemod | Edmonds, WA | Lab management software |
| Onkor Pharma | , | 10 year old company with no product or website |
| Fibronox | , | No website, Jul 2019 - May 2023 |
| Dompé | Milan, Italy | Biologics, Small Molecules, OTC |
| M2 Medical | , | Now Asante Solutions |
| , | Website down Dec 2025 - Apr 2026 | |
| Alverix | , | Acquired by BD, Jan 2014 |
| Kerecis | Reykjavik, Iceland | Wound Healing |
| Performance Cell Manufacturing | , | Renamed Cellipoint Bioservices |
| Tekmira Pharmaceuticals | , | Changed name to Arbutus Biopharma, Jul 2015 |
| Definiens | , | Acquired by MedImmune, Nov 2014 |
| New England Biolabs | Ipswich, MA | Reagents, Enzymes, Purification |
| Getinge | Mumbai, India | Medical Technology |
| Unchained Labs | Shanghai, China | Tools for biologics research & development |
| DNAe | Carlsbad, CA | Next-gen Sequencing |
| Pharmalucence | , | Fully integrated into Sun Pharma |
| Accellacare | Knoxville, TN | Clinical Research |
| Signant Health | Blue Bell, PA | eClinical Solutions |
| Kenox Pharmaceuticals | Monmouth Junction, NJ | Aerosol Drug Delivery |
| Pierre Fabre | Saint Julien en Genevois, France | Oncology, derm / cosmetics |
| Prolifaron | , | Acquired by Alexion, Sep 2000, $41M |
| , | Website down May 2025 - Sep 2025 | |
| Opko Biologis | Kiryat Gat, Israel | Bio-betters |
| Estrigenix Therapeutics | Milwaukee, WI | Mental Health of Menopausal Women |
| InnFocus | , | Acquired by Santen, Jul 2016 |
| Phenocell | , | Acquired by Axol Bioscience, Oct 2024 |
| Phosplatin Therapeutics | , | Renamed Promontory Therapeutics, May 2022 |
| A1M Pharma | , | Renamed Guard Therapeutics |
| Henlius Biopharmaceuticals | Shanghai, China | Biosimilars |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| NeuroRecovery Technologies | , | Merged with GTX Medical, Oct 2019 |
| SEQENS | Limay, France | Contract manufacturing, Proprietary APIs |
| TCXpress | , | Renamed BlueSphere Bio |
| CyGenica | Pune, India | Nanomolecular Drill, Non-Viral Delivery Platform |
| SynAgile | , | Doesn't seem active, Mar 2024 |
| Everest Clinical Research | Markham, ON | Clinical CRO |
| CSL Behring | King of Prussia, PA | Biologics |
| Contraline | Charlottesville, VA | Reversible Male Contraception |
 |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Aquatrove BioSciences | , | Bought by SASMAR, Aug 2016 |
| Quanttus | , | Moved to Mountain View, Site down May 2017, presume gone |
| Antigenics | , | Renamed Agenus, Jan 2011 |
| Stereotaxis | St. Louis, MO | Surgical Navigation System |
| VolitionRx | Singapore, Singapore | Cancer Diagnostics |
| Innovative Biosensors | , | Website gone Jul 2015-Feb 2016 |
| AdProtech | , | Acquired by Inflazyme Pharmaceuticals, Apr 2004 |
| Arresto Biosciences | , | Bought by Gilead, Jan 2011, $225M |
| Lumos Diagnostics | Carlsbad, CA | POC Diagnostics |
| Graphite Bio | , | Merged with LENZ Therapeutics, Mar 2024 |
| Pulmonx | Redwood City, CA | Lung disease treatments |
| Amphora Medical | , | Shut down May 2019 |
| Sumo Biosciences | , | Seem to have rebranded as Oncovalent Therapeutics, 2020 |
| Ogeda | , | Bought by Astellas, May 2017, €500M |
| Upjohn | , | Merged with Pharmacia in 1995 to become Pharmacia & Upjohn |
| Biofidelity | Cambridge, UK | Genetic Testing Technology |
| Enovis | Lewisville, TX | Various Medical and Surgical Devices |
| Obenomics | , | No website Apr 2014 |
| LGM Pharma | Colorado Springs, CO | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Veryan Medical | Horsham, UK | Helical Stent |
| Rad Pharm | , | Merged with Medifacts, became CoreLab Partners |
| Biomea Fusion | San Carlos, CA | Small Molecules Targeting Cancer |
| Sentinel Diagnostics | Milan, Italy | In Vitro Diagnostics |
| Lupin | Maharashtra, India | Generics |
| Florida Biotechnologies | , | Acquired by NAYA Biosciences, Jan 2024, $20M |
| Amgen | Cambridge, MA | Small Molecules, Biologics |
| Imago Pharmaceuticals | , | Website taken over by fashion Jan 2023; Website down Oct 2022 - Jan 2023; 3 ex Elan employees bought up an Elan program, sold it, using funds for JNK program |
| Algynomics | , | Acquired by Proove Biosciences, May 2016 |
| ProtaGene | Dortmund, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Delta-Vir | , | Website down Mar 2023 |
| Circio | Oslo, Norway | Immuno-oncology, Oncolytic Virus |
| GeneDx (old) | , | Acquired by Sema4, Jan 2022, $623M |
| WCCT Global | , | Acquired by Altasciences, Feb 2021 |
| Outpace Bio | Seattle, WA | Smart Cell Therapies |
| Nautilus Biotechnology | San Carlos, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| EG 427 | Paris, France | Pinpoint Gene Therapy |
| Biosense Webster | , | Rolled in to J&J Medtech; Created out of Merger between J&J-owned Cordis Webster & Biosense, Aug 1998 |
| Staten Biotechnology | , | Website down Dec 2023 - Jul 2024 |
| TE Connectivity | Suzhou, China | Contract Medical Devices |
| Modern Biosciences | , | Bankrupt, Jan 2024 |
| Nucleus RadioPharma | Davidson, NC | Radiotherapy CDMO |
| Disarm Therapeutics | , | Acquired by Eli Lilly, Oct 2020, $135M + $1.225B milestones |
| Nanion | Munich, Germany | Automated patch clamp instruments, membrane biophysics analyzers, and cell analytics platforms |
| Metagenomi | Emeryville, CA | Gene-Edited Microbial Treatments |
| MilliporeSigma | Rockville, MD | Biosafety testing, analytical development, and cell bank manufacturing services |
| Stereotaxis | Amsterdam, Netherlands | Surgical Navigation System |
| X-gen Pharmaceuticals DJB | Horseheads, NY | Generic Small Molecules |
| Neomend | , | Acquired by Bard, Oct 2012, $140M |
| Siegfried | Hameln, Germany | Contract Drug Manufacturing, APIS, Development |
| Greenwich Biosciences | , | Acquired by Jazz Pharmaceuticals, May 2021 |
| Gardedam Therapeutics | , | Merged with CANTABio Dec 2015 |
| Opus Genetics | Raleigh, NC | Ophthalmology Gene Therapy |
| Avatar Medical | Paris, France | Surgical Visualization |
| Alkahest | San Carlos, CA | Aging therapy using blood components |
| Microbot Medical | Yoqneam, Israel | Micro-robot assisted medical technologies |
| Restorative Therapies | Nottingham, MD | Functional Electrical Stimulation |
| Longboard Pharmaceuticals | , | Acquired by Lundbeck, Oct 2024; Arena Pharmaceuticals spinout |
| Moderna Therapeutics | Melbourne, Australia | RNA Therapies |
| Novum Pharmaceutical Research Services | Scarborough, ON | Clinical Research |
| SIA Pharma | , | Website down Apr 2023 - Sep 2023 |
| Indel Therapeutics | , | Gone. Site disappeared 2014 |
| 10BioSystems | , | Website Gone, Apr 2016 |
| CellChorus | Houston, TX | Visual AI on Time-lapse Imaging Microscopy in Nanowell Grids |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| AccelaPure | , | Bankrupt 2007 |
| Corus Pharma | , | Bought by Gilead, Aug 2006 |
| Prosolia | , | Website down Mar 2021 - Sep 2021 |
| Zila | , | Bought by Tolmar, Jul 2009 |
| SciGen | , | Bough by Yifan Pharmaceutical, Aug 2018 |
| Immage Biotherapeutics | , | Out of money, disbanded Aug 2017 |
| eEnzyme | Gaithersburg, MD | Biological reagents and bio-assay kits |
| Spring Bioscience | , | License antibodies to Abcam; Bought by Ventana 2007 |
| WaVe Life Sciences | Kagoshima, Japan | Stereopure oligonucleotides |
| Microtest | , | Acquired by Accuratus Lab Services, Jul 2014 |
| Dornier MedTech | Webling, Germany | Urology Devices |
| Novadaq | , | Bought by Stryker, Sep 2017 |
| Pel-Freez Biologicals | Rogers, AR | Biologicals for Research |
| Nuvisan | Neu-Ulm, Germany | Drug discovery, preclinical, clinical development, manufacturing services |
| Aspira Women's Health | Austin, TX | Diagnostics |
| Cleveland Medical Devices | Cleveland, OH | Sleep Testing Devices |
| Excelmab | Guangzhou, China | Bispecific Antibody Platform |
| Mozart Therapeutics | Seattle, WA | CD8 Treg cell modulators |
| Quantificare | Biot, France | Medical Imaging |
| Alderaan Biotechnology | , | Website down Mar 2025 - Aug 2025 |
| Angion Biomedica | , | Acquired by Elicio Therapeutics, Jun 2023 |
| GSK | Worthing, UK | Small Molecules, Vaccines, Biologics |
| Frontera Therapeutics | Suzhou, China | Gene Therapy Development |
| Auxogyn | , | Changed name to Progyny, Apr 2015 |
| Cilag | , | Joined J&J 1959 |
| Audentes Therapeutics | , | Acquired by Astellas, Jan 2020, $3B |
| Oxford Biomedica | Bedford, MA | CDMO, AAV manufacturing |
| BenuBiopharma | , | Shut down Sep 2023 |
| Schrodinger | Portland, OR | Computation Drug Discovery Platform |
| Axplora | Raubling, Germany | API CDMO |
| SJ Pharma | , | Website gone, Nov 2018 |
| SEQENS | Turku, Finland | Contract manufacturing, Proprietary APIs |
| Genewiz | South Plainfield, NJ | Sequencing, Biotech Services |
| Nuclivision | Gent, Belgium | Software solution that uses state-of-the-art AI algorithms to enhance the quality of PET scans |
| BioReperia | Linköping, Sweden | Cancer Diagnostics Consulting |
| Nfocus Neuromedical | , | Shut Down Mar 2013; fka CardioVasc |
| Coloplast | Humlebæk, Denmark | Wound care, surgical, bladder, bowel devices |
| CS Genetics | Cambridge, UK | Single Cell Genomic Analysis |
| OncoImmune | , | Acquired by Merck, Nov 2020, $425M |
| Molecular Biology Resources | Milwaukee, WI | Molecular Biology Kits, Services |
| Raland Therapeutics | , | Renamed Efferent Labs, May 2015 |
| Eisbach Bio | Planegg-Martinsried, Germany | Oncology Treatments |
| Unchained Labs | Brighton, MA | Tools for biologics research & development |
| Precision Therapeutics (3) | , | Renamed Alnylam |
| Protein Sciences | , | Acquired by Sanofi, Aug 2017, $650M + $100M milestones |
| Suir Pharma | , | Bankrupt, May 2016 |
| Applied Molecular Evolution | , | Bought by Eli Lilly, Feb 2004 |
| Innovare | , | Website under construction, Aug 2021 -May 2022 |
| NVIGEN | Campbell, CA | Nanoparticle Delivery for Imaging |
| ClearNote Health | San Mateo, CA | Liquid Biopsy |
| GandW Laboratories | , | Seems to have sold itself off by Oct 2021 |
| Immudex | Virum, Denmark | Diagnostics & Reagents |
| Cyberval | , | Seems inactive Feb 2024 |
| Qurin Diagnostics | Leiden, Netherlands | non-invasive, urine-based cancer diagnostics |
| , | Renamed Lunai Bioworks, Aug 2025; Merging with BioSymetrics; fka Enochian Biosciences; fka DanDrit | |
| SNBL | , | Acquired by Altasciences |
| Rejuve Therapeutics | Beltsville, MD | Gene therapy drug development company researching senescent cell solutions. |
| Neurophet | Seoul, Korea | AI-Image Processing |
| Associates of Cape Cod | East Falmouth, MA | Endotoxin Testing |
| Applied Molecular Genetics | , | Renamed Amgen |
| Hansen Medical | , | Bought by Auris Surgical, Apr 2016, $40M |
| 1molar | , | Website down Jul 2021 - Dec 2021 |
| Advanced Clinical | Guildford, UK | Clinical Research Organization |
| Heprotech | , | Around since at least 2012, nothing but a single page Google Website |
| Nemaura Pharma | , | Seems gone Mar 2025, stopped filings reports, previsouly outsourced everything and layoffs; Website down Oct 2024 - Mar 2025 |
| Tangshian Yian Biological Engineering | , | Acquired by Sinovac |
| Molecular Targeting Technologies | , | Website copyright 2012 as of Apr 2021 |
| Oxford Immunotec | , | Acquired by Perkin Elmer, Mar 2021, $591M |
| PHASE Scientific Americas | Garden Grove, CA | Diagnostics |
| Seaside Therapeutics | , | Apparently Defunct. Site Gone Apr 2014. Bad news in 2013 |
| Theon Therapeutics | , | Renamed Theonys, Aug 2021 |
| ImmunGene | , | Merged into new company, Apr 2019 |
| Maxis Clinical Sciences | London, UK | Clinical Research Consulting |
| 3P Biopharmaceuticals | , | Merged with Biovian, Feb 2024 to become 3PBIOVIAN |
| AbbVie | Worcester, MA | Biologics, Contract Manufacturing |
| Sequence Bio | St. John's, NL | Genomic analysis for drug targets |
| , | Renamed Cellixx, May 2026 | |
| Renibus Therapeutics | Southlake, TX | Small Molecules |
| ETAGEN Pharma | , | No reports filed 2018 thru Aug 2021 |
| WaveBreak | , | Renamed Wren Therapeutics, Apr 2024 |
| Ikena Oncology | , | Merged with Inmagene, Jul 2025; fka Kyn Therapeutics |
| Actus Therapeutics | , | Website down Nov 2019 - Feb 2019 |
| AngioChem | , | All employees gone, no info, presumed gone |
| , | Website down Oct 2025 - Jan 2026; Residential Address, Jun 2024 | |
| Scenic Biotech | Amsterdam, Netherlands | Genetic Modifier Targeting |
| Irvine Center for Clinical Research | , | Now Irvine Clinical Research |
| Gene Logic | , | Bankrupt |
| Vision Genomics | , | Website Gone, Jul 2016 |
| AVE Science & Technology | Changsha, China | Analysis Machines |
| Gallus | , | Bought by Patheon, Aug 2014 |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Vantia Therapeutics | , | Liquidated Feb 2021 |
| PathoVax | , | Website down Nov 2024 - Apr 2025 |
| Ajinomoto Bio-Pharma Services | San Diego, CA | Contract Manufacturing |
| Cellestis | , | Acquired by Qiagen Aug 2011 |
| Nautilus Neurosciences | , | Sold main drug in 2013. Don't seem active |
| Gelesis | , | Chapter 7 bankruptcy, Nov 2023 |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| MIGS | , | Acquired by DNA2.0, Apr 2016, |
| LiNA MEDICAL | Sady, Poland | Minimally invasive gynecology |
| Cangene | , | Acquired by Emergent Biosolutions, Dec 2013, $222M |
| Dornier MedTech | Tokyo, Japan | Urology Devices |
| Twist Bioscience | South SF, CA | Synthetic DNA, genes and libraries |
| Altruist Biologics | Suzhou, China | Biologics CDMO |
| Bausch Health | Laval, QC | Small Molecules |
| Z-Factor | , | Centessa Company |
| Direct Flow Medical | , | Shut down, Nov 2016 |
| Ezose Sciences | , | Rebranded as S-bio |
| Vyome Biosciences | , | Renamed Vyome Therapeutics |
| Biomeme | Philadelphia, PA | Portable real-time PCR |
| Lineage Therapeutics | , | Acquired by Impax, Mar 2015 |
| ZeptoMetrix | Buffalo, NY | Infectious Disease Diagnostics |
| InVivo Therapeutics | , | Chapter 11 Bankruptcy, Feb 2024, winding down |
| PharmaVigilant | , | Gone 2014 |
| Thrive Informatix | San Ramon, CA | Clinical Research |
| Collegium Pharmaceutical | Stoughton, MA | Drug Release Technology |
| Mendaera | San Mateo, CA | Medical Robotics |
| Labatec Pharma | Geneva, Switzerland | Small Molecules, Specialty |
| ViraSource | , | Shut Down 2023; Website down Apr 2024 - Jul 2024 |
| Stem Cell Theranostics | , | Gone Sep 2018 |
| UCB Pharma | Seattle, WA | Small Molecules, Biologics |
| Recipharm | Karlskoga, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Blue Stream Labs | , | Acquired by Charles River Labs, Jun 2016 |
| Vicept Therapeutics | , | Acquired by Allergan, 2011 |
| Asia Regulatory and Quality Consultancy | Singapore, Singapore | Medical Device Registration Services |
| Altair Clinical | , | Bought by Accelovance, Feb 2015 |
| SolveBio | , | Acquired by QuartzBio, Jan 2023 |
| LUZITIN | , | Employees all moved on, Aug 2023 |
| , | Website down Jan 2026 - May 2026 | |
| Cue Health | , | Shut down May 2024 |
| , | Website down Oct 2025 - Feb 2026 | |
| Xcelris Genomics | , | Website down Jan 2021 - Jul 2021; fka Virion Health |
| VeonGen Therapeutics | Planegg, Germany | AAV Gene Therapy |
| Sonata Biosciences | , | Website gone May 2021 - Aug 2021 |
| EZ Biosystems | College Park, MD | Transfection Reagents |
| Biotronik | Berlin, Germany | Pacemakers, implantable defibrillators, stents and remote patient management. |
| Ions Pharma | , | Website copyright 2005 as of Mar 2021 |
| Polyneuron Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Lubrizol Life Science Health | Cleveland, OH | Specialty Chemicals, Contract Development & Manufacturing |
| Sequoia Pharmaceuticals | , | Folded |
| Northumbria Pharma | Sedgefield, UK | Generics, Regulatory/Quality Services |
| Ampac Analytical | , | part of SK pharmteco |
| Emotional Brain | , | Offloaded all IP, Freya Pharma Solutions obtained Lybrido |
| AlphaGenix | , | Gone 2014 |
| Biofourmis | Needham, MA | AI for adverse event prediction |
| Piramal | Morpeth, UK | CDMO |
| Orthopeutics | , | Impossibly ancient website, Mar 2024; IP acquired Apr 2022 |
| , | Acquired by Boston Scientific, Jan 2025 | |
| Epeius Biotechnologies | , | Renamed GenVivo, Jun 2018; Website Gone as of Jul 2013 |
| QuatroBio | , | No website, no info Apr 2019 - Jan 2025 |
| Jupiter Endovascular | Menlo Park, CA | Endovascular Device for Pulmonary Embolism |
| Inflazome | , | Acquired by Roche, Sep 2020, $450M |
| Polymun Scientific | Klosterneuburg, Austria | Contract Development & manufacturing |
| PCI Synthesis | , | Rebranded Seqens, 2019 |
| Landos Biopharma | , | Acquired by AbbVie, May 2024, $137.5M |
| ParinGenix | , | Gone, 2012? |
| AGC Biologics | Bothell, WA | Contract Manufacturing - Biologics |
| Flen Pharma | , | Now Flen Health |
| Laboratoires CTRS | , | Website taken over Nov 2023 - Feb 2024 |
| AgNovos Bioscience | Rockville, MD | Osteoporosis Treatment |
| Celerion | Montreal, QC | Clinical Research |
| Ipsen | Tianjin, China | Small Molecules, Biologics |
| Acorda Therapeutics | , | Filing Chapter 11 Bankruptcy, Apr 2024 |
| Reset Therapeutics | , | Renamed Synchronicity Pharma, Mar 2019 |
| BGI | Shenzhen, China | Genetic Testing |
| Mirna Therapeutics | , | Merged with Synlogic, Aug 2017 |
| Fibroheal Woundcare | Bengaluru, India | Wound Care |
| Esculon | , | Seems defunct, employees gone |
| AmbioPharm | North Augusta, SC | Peptide APIs, Generic Peptides, Vaccine Services, Analytical |
| Biomicro Systems | , | No website Jun 2019, founded 1997 |
| Druggability Technologies | , | Renamed Tavanta Therapeutics, Sep 2020 |
| Curi Bio | Seattle, WA | Human 3D tissue disease models (skeletal muscle, cardiac, NMJ) for drug safety, efficacy, & potency |
| Enterey | Irvine, CA | Life Science Consulting |
| Arrhythmia Research Technology | , | Renamed Micron Solutions, Mar 2017 |
| LondonPharma | , | Website down Dec 2022 - Apr 2023 |
| , | Gone 2023, website taken over by a designer | |
| InteKrin | , | Owned by Coherus Biosciences |
| Lucerna | Brooklyn, NY | RNA-based research reagents |
| Paragonix Technologies | Waltham, MA | Organ Transport System |
| Tara Innovations | New York, NY | Contract R&D, Formulation (proprietary & contract) |
| Ultromics | Oxford, UK | AI-Interpretation of Echocardiograms |
| Life Chemicals | Niagara-on-the-Lake, ON | Screening Libraries, Chemical Synthesis |
| Cook Biotech | , | Acquired by RTI Surgical, Feb 2024 |
| Meda Biotech | , | Seems inactive, Feb 2025 |
| BioFire Diagnostics | Salt Lake City, UT | Diagnostics System |
| Isis Biopolymer | , | Website taken over |
| Aura Biosciences | Boston, MA | Delivery by Pseudo-Viruses |
| Parsolex | , | |
| CellPrint Biotechnology | , | Website down Jan 2024 - Jul 2024 |
| QuantaBio | Beverly, MA | PCR equipment |
| Releviate Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| SpineThera | , | Part of Frenelle Pharma, Feb 2025 |
| Calzada | , | Renamed Polynovo |
| Infinitopes | Oxford, UK | Vaccines |
| , | Website down Jan 2026 - Feb 2026, CEO gone Dec 2025 | |
| , | Acquired by Calibre Scientific, Jan 2024 | |
| Avastus Preclinical Services | Cambridge, MA | Preclinical Services |
| X-Nav Technologies | Lansdale, PA | Dental Surgery Navigation System |
| Aethon Therapeutics | New York, NY | Antibody immunotherapies for tumors that have developed resistance |
| Vitrology | , | Acquired by SGS, May 2012 |
| Advanced Biohealing | , | Bought by Shire 2011, Now Shire Regenerative Medicine |
| Incepta Vaccine | Dhaka, Bangladesh | Vaccine Production |
| Aerovance | , | Gone, don’t know where |
| Intra-Cellular Therapies | Bedminster, NJ | Small molecules for neurology |
| NeoTrail Therapeutics | , | |
| Irazu Biodiscovery | , | Presumed gone, not too serious in first place |
| , | Acquired by RTI Surgical , Nov 2024 | |
| Eyenovia | , | Pivoted to crypto/blockchain, Jul 2025 |
| Interdict | San Francisco, CA | Small Molecules |
| 480 Biomedical | , | Renamed Lyra Therapeutics, Sep 2018 |
| Ultragenyx Pharmaceutical | Novato, CA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| LunaDNA | , | Shutting down Jan 2024 |
| Accurus Biosciences | Richmond, CA | Cellular & Antibody Services |
| Genprex | Austin, TX | Non Viral Gene Delivery |
| SHL Medical | Deerfield Beach, FL | Medical Device assembly, labeling, packaging |
| Menarini | Florence, Italy | Biologics |
| Beeline Therapeutics | , | Shut down Jul 2021 |
| Xhale | , | Acquired by Philips, Aug 2018 |
| Dandelion Science | Hoboken, NJ | AI neuromodulation platform |
| Norgine | Milan, Italy | Specialty Pharma |
| VG Life Sciences | , | Shell company |
| Avitia | Montreal, QC | AI Cancer Diagnostics |
| Portrai | Cambridge, MA | Antibody, antibody fragment, peptides |
| Exsilio Therapeutics | , | Renamed Averna Therapeutics, Jan 2025 |
| Nangenex | , | Website down Sep 2020 - Jan 2021 |
| Ipsen | Cambridge, MA | Small Molecules, Biologics |
| Fob Synthesis | , | Exceptionally outdated website Nov 2019 (ca. 2005) |
| ProMed Prototypes | Plymouth, MN | Complete in-house mold design, mold build, and prototype component manufacturing. |
| BiomX | Ness Ziona, Israel | Microbiome-based Therapeutics |
| StemProtein | , | Website gone Jul 2019, possibly subsumed into parent Stemedica |
| Millipore | Danvers, MA | Purification, Analytic Biologics, Discovery |
| Active Motif | Carlsbad, CA | Epigenetics Research products |
| Cancervax | , | Acquired by Micromet, May 2006 |
| AAVP Biosystems | , | Renamed PhageNova Bio, Nov 2018 |
| OMC Medical | Horsham, UK | Regulatory Consulting |
| Stada | Banja Luka, Bosnia & Herzegovina | Generics |
| Groove Biopharma | , | Gone 2015 |
| Churchill Pharmaceuticals | , | Website down Mar 2024 - Jul 2024 |
| Pace | Huntersville, NC | Analytical Testing, CDMO |
| Intera Oncology | Newton, MA | Oncology and Neuromodulation Drug Delivery |
| Azopharma | , | Bankrupt, Apr 2010 |
| Edge Therapeutics | , | Acquired by PDS biotechnology, reverse merger, Mar 2019 |
| Taxon Biosciences | , | Acquired by DuPont, Apr 2015 |
| Taligen Therapeutics | , | Acquired by Alexion |
| Vor Biopharma | Cambridge, MA | CAR-T Stem Cell Therapy |
| Plectonic Biotech | Hallbergmoos, Germany | Logibody Technology |
| Klinsel | Kuala Lumpur, Malaysia | Clinical Research |
| Insilico Medicine | Hong Kong, China | In Silico Drug Discovery |
| Lonza | Tokyo, Japan | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Acquired by ETAP Group, Oct 2023 | |
| Sciecure Pharma | Monmouth Junction, NJ | Generics |
| Hatchtech | , | Product licensed to Dr. Reddy's |
| Just Biotherapeutics | , | Acquired by Evotec, Jul 2019, up to $90M |
| AlphaMol Science | Shenzhen, China | Therapeutics targeting GPCR |
| Motus GI | Fort Lauderdale, FL | Endoscopy Technology |
| Green Valley Pharmaceuticals | Shanghai, China | Alzheimer's Treatment |
| Anelixis Therapeutics | , | Acquired by Novus Therapeutics, Sep 2020; fka Anelixis Pharmaceuticals |
| Charles River Laboratories | Calco, Italy | Research Animal Models and Preclinical Research |
| CyVek | , | Acquired by Bio-Techne, 2014 |
| Myotwin | Göttingen, Germany | Heart Muscle Platform |
| Prognos | New York, NY | Clinical & Genomic Lab data |
| Bio Delivery Systems | , | Renamed ImmuPharma, 2005 |
| Syner G BioPharma Group | Framingham, MA | CMC Consulting |
| Art Bioscience | Rehovot , Israel | DMD Gene Therapy |
| OncoDNA | Gosselies, Belgium | Cancer diagnostic test based on NGS and IHC technology |
| Azzur | , | Facilities now Chrysalis, Consulting business sold to Eliquent after Bankruptcy, Mar 2025 |
| Octapharma | Lingolsheim, France | Plasma Products |
| inRegen | , | Acquired by ProKidney via SPAC, Jan 2022; fka RegenmedTX |
| , | Website down Jan 2026 - May 2026; Co-located with GC Pharma | |
| Taiga Biotechnologies | , | Website down Mar 2024 - Jul 2024 |
| Zai Lab | South SF, CA | Small Molecules |
| Blackrock Neurotech | Salt Lake City, UT | Brain-Computer Interfaces |
| Minoryx Therapeutics | Barcelona, Spain | Small Molecules for Rare Diseases |
| Vaccinex | Rochester, NY | Human therapeutic monoclonal antibodies and other targeted biological therapies |
| My Intelligent Machines (MIMs) | , | Website down Jun 2024 - Nov 2024 |
| OncoFusion | , | Website gone Jan 2020, no employees on LinkedIn |
| Hubei Minkang Pharmaceutical | , | Site down, Aug 2018 |
| Fratagene Therapeutics | , | Shut down Dec 2022 |
| BioQuiddity | , | Changed name to BioQ Pharma, Oct 2015 |
| Cyclomedica | Kingsgrove, Australia | Lung Imaging |
| Ambry Genetics | Aliso Viejo, CA | Genetic Testing |
| Quratis | Cheongju, Korea | Vaccines |
| Novel Microdevices | Baltimore, MD | POC Diagnostics |
| Promega | San Luis Obispo, CA | Vast Catalog of Biotechnology Products |
| Applied Therapeutics | New York, NY | Small Molecules |
 |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Carbiotix | Lund, Sweden | Gut Microbiota Testing |
| Neopeutics | South SF, CA | Drug discovery contract research |
| Esper Therapeutics | , | Shut down 2016 |
| The Binding Site | , | Acquired by Thermo Fisher, Jan 2023, $2.6B |
| 14M Genomics | , | Shut down, Feb 2016 |
| Jnana Therapeutics | Boston, MA | SLC transporter Drug Discovery |
| Generex Biotechnology | , | Website gone Feb 2024 |
| Tabuk Pharmaceuticals | Riyadh, Saudi Arabia | Small Molecules |
| Avelos Therapeutics | Seoul, Korea | Treating Undruggable Cancer Cells |
| Qyuns Therapeutics | Taizhou, China | Antibody drugs for autoimmune and allergic diseases, biosimilars |
| Ajinomoto Bio-Pharma Services | Osaka, Japan | Contract Manufacturing |
| Alexo Therapeutics | , | Renamed ALX Oncology, Jun 2018 |
| Sanarus | , | Acquired by Hologic, 2020 |
| enVVeno Medical | Irvine, CA | Bioprosthetic Devices & Technologies |
| Genotype Diagnostics | , | Part of Paliwoda Group |
| Amasa Therapeutics | , | Website being updated Apr 2024 - May 2025, Linkedin gone Feb 2025 |
| RiconPharma | , | Renamed Ingenus Pharmaceuticals, 2019 |
| Sienna Biopharmaceuticals | , | Filed Chapter 11 bankruptcy, Sep 2019 |
| CardioCreate | , | Shut Down Jun 2020 |
| Anaheim Clinical Trials | , | Now CenExelACT |
| Pharmadule Morimatsu | Stockholm, Sweden | Modular Pharma Manufacturing Facilities |
| Angitia Biopharmaceuticals | Guangzhou, China | Bispecific Antibody |
| VedaBio | San Diego, CA | Molecular Detection, Gene Editing |
| Anaphore | , | Acquired RuiYi, rebranded as RuiYi |
| Lexent Bio | , | Acquired by Foundation Medicine, Jun 2020 |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| SalveoDx | , | Merged with ImmunArray, Aug 2019 |
| AlphaCore Pharma | , | Bought by MedImmune, Apr 2013 |
| Baxter | Grosotto, Italy | Medication Delivery |
| RaySearch Laboratories | Singapore, Singapore | Cancer Research Software |
| Angelica Therapeutics | , | Gone 2018 |
| 3-V Biosciences | , | Renamed Sagimet Biosciences, Aug 2019 |
| OncoViRx | , | Website down Feb 2021 - Sep 2021 |
| Genetic Therapy | , | Bought by Sandoz, Jul 1995, #295M |
| Endologix | Irvine, CA | Medical Devices |
| Freyr Solutions | Lörrach, Germany | Regulatory Consulting |
| ReceptorPharma | , | Website down Jan 2025 - Mar 2025 |
| Akriveia Therapeutics | , | Rebranded as Akrevia Therapeutics |
| ONFAB | Eden Prairie, MN | Custom-designed, single-use and retrofit flexible isolators |
| Amaranth Medical | , | Website gone, Apr 2019 |
| Locemia Solutions | , | Sole product acquired by Eli Lilly, Oct 2015 |
| , | Renamed Carvolix, Feb 2026 | |
| Simondr | , | Website gone, President has new job |
| Parexel | Sheffield, UK | Clinical Research |
| SegWay Orthopedics | , | Acquired by Trice Medical, Feb 2019 |
| , | Acquired by Exact Sciences, Sep 2023; Acquired by Agilent, Apr 2021, $550M | |
| Xenogenics Corporation | , | No info, website gone, presumed gone |
| Inverness Medical | , | Renamed Alere 2011 |
| , | Acquired by Worldwide Clinical Trials, Feb 2026 | |
| Primera Biosystems | , | Now PrimeraDx |
| Lab21 | , | Renamed Cambridge Analytical Laboratories, Dec 2019 |
| NMI TT Pharmaservices | Reutlingen, Germany | Preclinical contract research services, specialty: multiplex protein profiling services |
| Function Therapeutics | Milwaukee, WI | Protease-activated receptors |
| Ethos Biosciences | Logan Township, NJ | Assays & reagents |
| SGC Pharma | , | Website taken over, Nov 2016 |
| Pierre Fabre | Château-Renard, France | Oncology, derm / cosmetics |
| INTIO | , | Website down Jan 2021 - May 2021 |
| Cytecs | Münster, Germany | Cell Analysis |
| Kadmon Pharmaceuticals | , | Rebranded as Kadmon |
| RDD Pharma | , | Merged with Innovate Biopharmaceuticals, Apr 2020 |
| Coloplast | Brookshire, TX | Wound care, surgical, bladder, bowel devices |
| Navidea Biopharmaceuticals | Columbus, OH | Radiopharmaceuticals |
| Mission Therapeutics | Cambridge, UK | Small Molecules |
| Thermo Fisher | Grand Island, NY | Molecular Biology & Biotech Lab Products |
| Amplifold | , | DNA origami nanotechnology |
| CatSci | Cardiff, UK | Contract Research |
| Sansoro Health | , | Merged into Datica, Jun 2019 |
| Beckley Canopy Therapeutics | , | Acquired by Canopy Growth, Oct 2019 |
| BeyondSpring Pharmaceuticals | Florham Park, NJ | Small Molecules |
| Avalia Immunotherapies | , | Website down Jul 2023 - Oct 2023 |
| Amarantus Bioscience | , | No business filings since 2019 as of Mar 2021; Website down Mar 2021; Purchased a CBD/Hemp company Feb 2020 to provide cash flow (?) |
| PsyCheNomicS | , | Acquired by Novasite Pharmaceuticals, Jun 2005 |
| Stentys | , | Website down May 2021 - Oct 2021 |
| Imanis Life Sciences | Rochester, MN | Genetic & Cellular Research Products |
| Allegro Diagnostics | , | Acquired by Veracyte, late 2014 |
| Tera Discoveries | , | Renamed Cloud Pharmaceuticals, Jun 2014 |
| bioSyntagma | , | Website down Aug 2024 - Feb 2025 |
| cgtx-Peptide Development | , | Renamed conoGenetix Biosciences |
| Sanguine Biosciences | San Diego, CA | Biospecimen Collection |
| Future Fields | Edmonton, AB | Contract Protein Research |
| Aquinox Pharmaceuticals | , | Acquired via Reverse Merger by Neoleukin Therapeutics Aug 2019; Stopped all RD Jul 2018 |
| Azenta Life Sciences | Indianapolis, IN | Biostorage |
| Novo Nordisk | Gentofte, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Aethox Therapeutics | London, UK | Inhibitors |
| , | Acquired by GE Healthcare, 2021, $1.45B | |
| Novum Pharmaceutical Research Services | Las Vegas, NV | Clinical Research |
| Transine Therapeutics | , | Renamed Harness Therapeutics, Sep 2023 |
| Augurex Life Sciences | Vancouver, BC | Biomarker discovery & validation |
| Charles River Laboratories | Chatillon-sur-Chalaronne, France | Research Animal Models and Preclinical Research |
| , | Website down Dec 2025 - Apr 2026; Not registered in CA 2020 - Nov 2025 | |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| SpineSource | , | Website down Feb 2025 - Aug 2025 |
| Bioton | Ozarow Mazowiecki, Poland | Biosimilars, generics, creams, etc. |
| IST Innuscreen | Berlin, Germany | Reagents, Lab supplies |
| Umbra Therapeutics | , | Renamed Hyku Biosciences, Aug 2023 |
| , | Renamed Persevere Therapeutics, Feb 2026 | |
| Recipharm | Uppsala, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| EMS | Hortolândia, Brazil | Small Molecules |
| Leadingtac Pharmaceutical | Shanghai, China | Small Molecules |
| Manhattan Genomics | New York, NY | Gene Correction Therapies |
| deCODE Biostructures | , | Now Emerald Biostructures |
| AstraZeneca | Södertälje, Sweden | Small Molecules, Vaccines, Biologics |
| Tenet Medicines | , | Acquired by Eliem Therapeutics, Jun 2024 |
| Iproteos | , | Products now with Accure Therapeutics |
| Kirax | , | Website Gone |
| Yposkesi | , | part of SK pharmteco |
| Liminatus Pharma | , | Pivoting to crypto Jul 2025; Supposedly created to be acquired in a SPAC, never seems to have happened; Website down Aug 2023 - Sep 2023 |
| ReCerise Technologies | Seoul, Korea | Liver Therapies |
| TE Connectivity | Wilsonville, OR | Catheter manufacturing & development |
| VitalConnect | San Jose, CA | Cardiac Monitoring Patch |
| Transkaryotic Therapies | , | Acquired by Shire, 2005 |
| NeurOptics | Irvine, CA | Pupillometry |
| ViaCyte | , | Acquired by Vertex, Nov 2022, $320M |
| FibroTx | , | Doesn't seem active, LI page gone Nov 2023 |
| Coronado Biosciences | , | Renamed Fortress Biotech, Apr 2015 |
| Atrion Medical | , | Acquired by Nordson, Aug 2024 |
| Xenikos | , | Shut down early 2023 |
| WDSrx –Woodfield Distribution | , | Acquired by Reliable HealthCare Logistics |
| Lantibio | , | Website Gone, no news since 2007 as of Dec 2019 |
| CDR-Life | Zurich, Switzerland | Antibody for immuno-oncology and ophthalmology |
| Unichem Pharmaceuticals | East Brunswick, NJ | Generics |
| Surv Biopharma | Tokyo, Japan | Conditionally-replicating adenovirus |
| SparingVision | Paris, France | Retinal Gene Therapy Treatments |
| AbX Biologics | , | Renamed Abveris |
| Viseon | Irvine, CA | Minimally Invasive Spine Surgery |
| uBiome | , | Chapter 11 Bankruptcy, Sep 2019 |
| Cutanea Life Sciences | , | Acquired by Biofrontera, Mar 2019 |
| Areterna | Bethesda, MD | Raw materials and services to support mRNA and oligonucleotide manufacturing |
| Nu-Med Plus | , | Website down Sep 2022 - Feb 2023 |
| Pfizer | Wuxi, China | Small Molecules, Biologics, Vaccines |
| Nautilus Biotechnology | San Diego, CA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| SK Pharmteco | Rancho Cordova, CA | Small Molecule Development & Manufacturing |
| Harmac Medical Products | Buffalo, NY | Contract manufacturer of single-use medical devices |
| Taewoong Medical | Gimpo-si, Korea | Stents, Endoscopes |
| ZaltanPharma | , | Acquired by Riemser, Oct 2019 |
| Polyphor | , | Renamed Spexis, Dec 2021 |
| Niche Generics | Hitchin, UK | Contract Generics |
| BioMedFlex | , | Filings late Apr 2024 - Mar 2025, one founder died Jun 2024 |
| Novacea | , | Bought by Transcept |
| Asymptote | , | Acquired by GE Healthcare, Apr 2017 |
| ELS Solutions | São Paulo, Brazil | Strategic Advisory |
| Accellix | Jerusalem, Israel | On-demand Assays |
| iChek | , | Website gone Aug 2022 - Feb 2023 |
| Vibliome | , | Website down Oct 2024 - Mar 2025 |
| Epichem | Bentley, Australia | Synthetic and medicinal chemistry services. Extensive reference standards catalogue. Global delivery. |
| Daan Gene | Guangzhou, China | Diagnostics, Instruments, Reagents |
| SanBio Co Ltd | Tokyo, Japan | Regenerative Cell Medicine |
| Synergene Therapeutics | , | Doctor owner still indicates it exists, but doubtful |
| Allogene Therapeutics | South SF, CA | CAR-T |
| Lindus Health | London, UK | CRO |
| Parsagen Diagnostics | , | Acquired by Qiagen |
| Traffick Therapeutics | , | Asset sold to Vertex, Nov 2016 |
| Synactix Pharmaceuticals | , | Website down May 2022 - Sep 2022, Owner and sole employee moved for a diff university job |
| Excaliard | , | Bought by Pfizer 2011 |
| Beckman Coulter Diagnostics | Chaska, MN | Diagnostics |
| Euformatics | Espoo, Finland | Clinical NGS Data analysis software |
| StrataGent Life Sciences | , | Acquired by Corium, 2007 |
| FenoMark Diagnostics | Solna, Sweden | Diagnostics |
| Escala Therapeutics | , | Was Fortress Biotech, No website Mar 2020 - Dec 2020 |
| Ally Therapeutics | , | Shut down early 2021 |
| Celentyx | Oxford, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| Starodub | Nuland, Netherlands | Regulatory Consulting |
| Dorna Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| Core Clinical Research & Consultancy | , | Renamed Core Oncology |
| Qool Therapeutics | , | Gone Jan 2021 |
| Cytel | Hyderabad, India | Clinical software, statistical services |
| Xenios | , | Acquired by Fresenius, Nov 2016; formed out of merger between novalung & medos, 2013 |
| Applied Cardiac Systems | , | Now ACS Diagnostics |
| Yokogawa | Sugar Land, TX | Cell Analysis, Biological Containment, Equipment |
| AkaRx | , | Acquired by Eisai, Dec 2009 |
| Parexel | Durham, NC | Clinical Research |
| Cell Culture Biosolutions | , | Website gone Nov 2020, not listed in CA business registry |
| , | Website down Aug 2025 - Jan 2026 | |
| Phoresa | , | Shut down Mar 2018 |
| Jetequip | Boucherville, QC | Fluid Handling |
| AGC Biologics | Copenhagen, Denmark | Contract Manufacturing - Biologics |
| Biomagnetics Diagnostics | , | Forfeited Business in CA, Jul 2006; Website not updated since 2010 |
| Sairiyo Therapeutics | , | Acquired by PharmaDrug, Feb 2021 |
| ArrePath | Princeton, NJ | Machine learning-based platform for the discovery of new classes of anti-infectives |
| Repairon | Göttingen, Germany | iPSC to create tissue for heart repair |
| Othera Pharmaceuticals | , | Acquired by Colby Pharmaceuticals 2012 |
| Enable Injections | Cincinnati, OH | Wearable Automated Injector Device |
| Mavalon Therapeutics | , | Shutting down Feb 2021 |
| FluidForm Bio | Waltham, MA | Human Tissue for Advanced Cell Therapy |
| Combinent BioMedical Systems | , | Shut down Nov 2013 |
| Claret Bioscience | Scotts Valley, CA | NGS Library Prep |
| Axeq Technologies | , | Created by Macrogen, Brought back into Macrogen, 2016 |
| Lucence Diagnostics | Singapore, Singapore | Cancer Detection |
| Merz Therapeutics | Raleigh, NC | Small Molecules |
| Enteris BioPharma | , | Renamed Mod3 Pharma, Mar 2025 |
| UroMems | Eybens, France | Implantable MyoElectroMechanical System |
| LyoGo | , | Website gone, all employees gone |
| Patheon | Whitby, ON | Contract Manufacturing and Development |
| Utah Medical | Dublin, Ireland | Devices focusing on women's health |
| Amaros | Menlo Park, CA | Ophthalmology Data Platform |
| Medallion Therapeutics | , | Shut down 2018 |
| PreCision Dermatology | , | Acquired Triax Pharmaceuticals, Renamed Onset Dermatologics |
| Ken Block Consulting | Richardson, TX | Regulatory Consulting for Medical Device Companies |
| Sterling Pharma Solutions | Cork, Ireland | Contract Development & Manufacturing - APIs |
| Dianomi Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| iBeCa Therapeutics | , | Website gone, Apr 2018 |
| NeoGenomics | Aliso Viejo, CA | Genetic & Diagnostic Testing |
| ContraFect | , | Website down Dec 2023 - May 2024 |
| Silicon Therapeutics | , | Acquired by Roivant, Feb 2021, $450M |
| Medicomp | , | Renamed ReactDx |
| 3PBIOVIAN | Turku, Finland | Contract Development & Manufacturing |
| Ixico | London, UK | AI-powered imaging analysis, imaging operations and central nervous system expertise from early phase to observational research. |
| Singapore Biotech | , | Website down Sep 2020 - Jan 2021 |
| Quantapore | , | Business filings 11 months late Nov 2023; LI page gone Nov 2023; CEO has full-time job elsewhere as of Oct 2023 |
| Samsung Bioepis | Incheon, Korea | Biologics, Biosimilars |
| Precision BioSciences | Durham, NC | Genome-editing enzymes, CAR-T |
| Scitaris & Co KG | Berlin, Germany | Strategy Consulting |
| Calchan | , | Shut down Dec 2020 |
| Regenera Pharma | , | Website gone Apr 2021 - Jun 2021 |
| ProMed Pharma | Plymouth, MN | Contract Manufacturing of Molded Dosage Forms and Combination Products |
| Asymchem | Beijing, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Pfizer | New York, NY | Small Molecules, Vaccines, Biologics |
| Wasatch Microfluidics | , | Renamed Carterra, May 2017 |
| , | Website down Jul 2025 - Mar 2026 | |
| Axoltis Pharma | Lyon, France | Neurological Peptide Drugs |
| Creoptix | , | Acquired by Malvern Panalytical, Jan 2022 |
| Satori Pharmaceuticals | , | Shut Down May 2013 |
| Lyophilization Services of New England | , | Acquired by PCI Pharma Services, Dec 2021 |
| Huya Bioscience | Shanghai, China | Compound Advancement |
| LabGenius Therapeutics | London, UK | Synthetic DNA library |
| NovaCardia | , | Bought by Merck, Jul 2007, $350M |
| Sujana Biotech | , | Website down Mar 2022 - May 2022, employees in other jobs |
| Natco Pharma | Manali, India | Generics, APIs, Contract Manufacturing |
| RadioRx | , | Now EpicentRx |
| ADMEcell | , | Dissolved, basically rebranded as Adari Cell Science, Jun 2020 |
| Saffron Therapeutics | , | Website down Oct 2021 |
| Biostate AI | Houston, TX | AI-Enhanced RNA Sequencing |
| Barofold | , | Assets Acquired by Pressure Biosciences, Dec 2017 |
| VersaPharm | , | |
| Agno Pharma | Lianyungang, China | Small molecule CRO, CDMO |
| Jubilant HollisterStier | Spokane, WA | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| Anterion Therapeutics | , | Bankrupt Feb 2012 |
| ProFarma | Vilnius, Lithuania | Biosimilars, Services |
| Boston Life Sciences | , | Renamed Alseres Pharmaceuticals, Jun 2007 |
| Immco Diagnostics | , | Acquired by Trinity Biotech, Aug 2013, $33M |
| Egis Pharmaceuticals | Budapest, Hungary | Generics |
| ABOzymes | , | Renamed Avivo, Sep 2022 |
| Astrum | Paris, France | Clinical Development CRO |
| MVI Health | , | Acquired by Penumbra, Sep 2018 |
| Ceregene | , | Acquired by Sangamo, Aug 2013 |
| Ottobock | Duderstadt, Germany | Prosthetics |
| FSG Bio | , | Changed name to Gossamer Bio, Dec 2017 |
| Neuron Therapeutics | , | Dissolved 2003, IP acquired by Integra LifeSciences |
| Vantage Medtech | Moonachie, NJ | Medical Device Design & Development |
| , | Assets acquired by Aptar, Jul 2025; fka Enteris BioPharma | |
| Penn Pharma | , | Bought by PCI Pharma Services, Jul 2014, $215M |
| , | Liquidating, Sep 2025 | |
| Evidenze | Barcelona, Spain | Clinical Research Organization |
| Applied Microarrays | , | Acquired by Schott, Sep 2021 |
| VaxNewMo | , | Renamed Omiose |
| OxStem | , | Shut down 2021; Oxford spinout |
| Biotica | , | Bankrupt. Assets sold May 2013 |
| Cerenis Therapeutics | , | Renamed Abionyx, Aug 2019 |
| Arrakis Therapeutics | Waltham, MA | RNA-targeted small molecules |
| Pain Therapeutics | , | Renamed Cassava Sciences, Mar 2019 |
| Protinhi Therapeutics | , | Shut Down May 2024 |
| Ethypharm | Saint-Cloud, France | Specialty Pharma |
| TNI Medical | , | Acquired by Masimo, Mar 2020 |
| Audubon Bioscience | Houston, TX | Biospecimens |
| Mai De Pharmaceuticals | , | Website Gone, nothing online about them |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| XuanZhu Pharmaceutical | , | Website down Oct 2022 - Mar 2023 |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Biogen | Cambridge, MA | Small Molecules, Biologics, Biosimilars, ASO |
| Daiichi Sankyo | Uxbridge, UK | Small Molecules |
| Abbkine Scientific | Wuhan, China | Biochemicals, antibodies, proteins, peptides, ELISA assay kits and various contract research offerings |
| Amferia Kills Bacteria | Mölndal, Sweden | Wound Care Antimicrobial |
| Diosynth | , | Bought by Organon, Jan 2005 |
| Berry Oncology | , | Website down Feb 2025 - Jun 2025 |
| SEQENS | Aramon, France | Contract manufacturing, Proprietary APIs |
| Hitachi Chemical Advanced Therapeutics Solutions | , | Renamed Minaris Regenerative Medicine, Sep 2020 |
| Crystal NAX | Cranbury, NJ | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Serica Technologies | , | Bought by Allergan |
| Cellenion | Portsmouth, UK | Single Cell Testing |
| Isla Pharmaceuticals | , | Website down Jan 2021 - Mar 2021 |
| Ultradian Diagnostics | , | Former CEO referred to company in the past tense as of Mar 2019 |
| Vironika | , | Website down Feb 2025 - Apr 2025, employees gone |
| Kite Pharma | London, UK | Engineered Autologous T Cell Therapy, CAR-T |
| Pinewood | , | Bought by Wockhardt, Feb 2013, €150M |
| Primity Bio | , | Acquired by Caprion Biosciences, Sep 2018 |
| Olfa Thera | San Francisco, | Small molecule therapeutics to treat cardiovascular and respiratory conditions |
| ERBC | Baugy, France | Non clinical CRO |
| BioreclamationIVT | , | Renamed BioIVT, Sep 2017 |
| RelonChem | Cheshire, UK | Generics |
| Synageva BioPharma | , | Acquired by Alexion, Jun 2015, $8.4B |
| Novo Nordisk | Seattle, WA | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Renamed Pixl.bio, Nov 2025 | |
| Xenco Medical | San Diego, CA | Surgical Devices |
| Cornerstone Pharmaceuticals | , | Changed name to Rafael Pharmaceuticals, Jun 2017 |
| Ellex | , | Acquired by Lumibird, Jun 2020 |
| BioStem Technologies | Pompano Beach, FL | Perinatal tissue products for use in regenerative therapies |
| H&A Scientific | Greenville, NC | LIMS, Stability Software |
| Xoft | , | Acquired by Elekta, Oct 2023 |
| Western Biologics | , | Dissolved, 1998 |
| AbGenomics | , | Renamed Altrubio |
| Scibase | Stockholm, Sweden | Complementary Information for Melanoma Detection |
| ISTO Biologics | Hopkinton, MA | Orthobiologics |
| , | Acquired by Sanofi, Dec 2025, $1.15B | |
| Nanologica | Södertälje, Sweden | Nanoporous Silica |
| NetBio | , | Renamed ANDE |
| , | Acquired by ImmunoPrecise, Apr 2022, €20M | |
| Qrons | , | Website down May 2025 - Jul 2025; worth almost nothing |
| Charles River Laboratories | Shrewsbury, MA | Research Animal Models and Preclinical Research |
| Refractal | , | Website down Mar 2023 - Dec 2023 |
| Axis Clinicals USA | Dilworth, MN | Clinical Trials |
| Kendle | , | Acquired by INC Research 2011 |
| Life Spine | Huntley, IL | Expandable Spinal Implants |
| Aktiia | Neuchâtel, Switzerland | Blood Pressure Monitor |
| Carmat | Vélizy-Villacoublay, France | Artificial Organs |
| Wound Management Technologies | , | Renamed WNDM Medical, Apr 2018 |
| Diartis Pharmaceuticals | , | Bought out by investors, Mar 2013. Not sure what will happen |
| Embla Systems | , | Acquired by Natus Medical, Sep 2011 |
| NX Pharmagen | , | Spun out a company and seems like no one works there |
| Epitomics | , | Bought by Abcam, Mar 2012, $155M |
| NAMSA | Chasse-sur-Rhône, France | Medical Research Organization - Medical Devices |
| Novotech | Seoul, Korea | Clinical Research |
| Euclid Systems | Sterling, VA | Corneal reshaping contact lenses for myopia |
| Helixrus | Seoul, Korea | Multi-Omics Tools |
| Keenova | Dublin, Ireland | Small Molecules |
| Myonexus Therapeutics | , | Bought by Sarepta, May 2019, $165M |
| Bangs Laboratories | Fishers, IN | Microspheres, beads |
| AstraZeneca | New Haven, CT | Biologics |
| Agilent | Cheshire, UK | High-Throughput Screening Equipment, Imaging instruments |
| Charles River Laboratories | Newark, DE | Research Animal Models and Preclinical Research |
| ToolBox Genomics | Draper, UT | Genetic Testing |
| 2C Tech | , | Website down Oct 2024 - Mar 2025; Business filings late Nov 2024 |
| QLD Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| MipSalus | Hørsholm, Denmark | Developing new proprietary drugs for treating all variants of hyperphenylalaninemia, diagnostics |
| Therabest | Seoul, Korea | iPSC |
| Aerovate Therapeutics | , | Merged with Jade Biosciences, Apr 2025 |
| OWC Pharmaceutical | , | Website down Jan 2022 - Jul 2022 |
| Simbex | Lebanon, NH | Biomechanical devices |
| NeuCyte | Mountain View, CA | iPSC platform for drug discovery |
| Aerogen | Galway, Ireland | Nebulizers |
| Navamedic | Oslo, Norway | Small molecule for mouth/throat, dermatology, urology, gynecology, cardiology, metabolism |
| Protea Biosciences | , | Website down Jul 2020 - Aug 2020; Bankrupt Dec 2017 |
| Artio Medical | , | Website down Jul 2023 - Oct 2023; fka Metactive Medical |
| Bioniche Life Sciences | , | Renamed Telesta Therapeutics |
| Compliment Corporation | , | Closed Dec 2011 |
| Acino | Kiev, Ukraine | Novel drug delivery formulations |
| Geneius Biotechnology | Natick, MA | Autologous, adoptive T-cell therapies |
| CellTivity Scientific | Paris, France | Biopsy Imaging |
| BIOLYPH | Chaska, MN | Lyophilization Services, Formulation & Device Design to Optimize Quality & Value of IVD & RUO Assays |
| BTgen Bio | Incheon, Korea | Biologics Contract work |
| BioVest | , | Bankrupt, restructured, twice, Was told by a spinout employee that Biovest is no longer operating (Jul 2016) |
| Eurofins Genomics | Louisville, KY | Genomic Supplies & Services |
| Microline PENTAX | , | Renamed Microline Surgical, Sep 2009 |
| Ribotargets | , | Merged with British Biotech, Mar 2003 |
| Enosi Therapeutics | , | Website down Feb 2025 - Jul 2025; aka Enosi Life Sciences |
| Xyntek | , | Segment of non-life science business |
| Brainwave Discovery | , | Outdated website, no employees on LI Jun 2023 |
| NeurAegis | , | Seems gone, Sep 2022 |
| Entheon Biomedical | , | Website down Jan 2023 - Sep 2023 |
| K2M | , | Acquired by Stryker, Nov 2018 |
| PKC Pharmaceuticals | , | 29 yr old company in RD stage |
| Stratatech | , | Bought by Mallinckrodt, Aug 2017, $76M + $121M milestones |
| Legend Biotech | Piscataway, NJ | Cell Therapy |
| , | Website down Sep 2025 - Dec 2025 | |
| N30 Pharmaceuticals | , | Renamed Nivalis Therapeutics |
| Nanna Therapeutics | , | Acquired by Astellas, Apr 2020 |
| Gilero | Shenzhen, China | Contract manufacturing of medical device & drug delivery systems and injection mold tooling |
| EPI Health | , | Rolled in to Novan Therapeutics, Mar 2023 |
| Tisbury Pharmaceuticals | , | CEO is with new company, website gone, company presumed gone |
| Basic Pharma | Geleen, Netherlands | Pharma CDMO, albumin |
| Zydus Pharmaceuticals USA | Pennington, NJ | Generics |
| LigaTrap | , | Acquired by Chromagenex, Apr 2025 |
| Propella Therapeutics | , | Acquired by Astellas, Dec 2023, $175M |
| Axxam | Milan, Italy | Drug discovery services |
| Autoscribe Informatics | Lakeville, MA | LIMS/Laboratory Software & Services |
| Sedor Pharmaceuticals | , | Website Down Nov 2022 - Apr 2023 |
| Arthrogen | , | Website down Jul 2021 - Sep 2021 |
| Alpha Biopharma (1) | , | CA-based, Presumed defunct |
| Adamas Pharmaceuticals | , | Acquired by Supernus, Nov 2021 |
| Newcells Biotech | Newcastle, UK | 3D in vitro Models |
| Scitaris & Co KG | Boston, MA | Strategy Consulting |
| Pathway Oncology | , | Acquired by Virax, Mar 2014 |
| Appia Bio | , | Shut down Aug 2025 |
| Soft Tissue Regeneration | , | Renamed Biorez, 2016 |
| hC Bioscience | , | Shut down Mar 2025 |
| ABS Biotechnologies | Tulln an der Donau, Austria | Stem Cell Technology for Drug Screening |
| Alvine Pharmaceuticals | , | Assets acquired by ImmunogenX, Mar 2016 |
| Universal Sensors | , | Now vantix DIAGNOSTICS |
| Cybelle Biosciences | , | No website Jun 2019, 2014 startup |
| Vcare PharmaTech | , | Website down Feb 2024 - Jul 2024 |
| , | Renamed PKx Bio, 2026 | |
| Delveinsight Business Research Group | Gurugram, India | Business Consulting |
| Voyager Therapeutics | Lexington, MA | AAV capsid Gene Therapy |
| Lumenis | Formello, Italy | Energy-based medical treatments |
| Providus Therapeutics | , | Dissolved, Sep 2016 |
| , | Website down Jun 2025 - Dec 2025 | |
| PSC Biotech | Pomona, CA | Consulting, metrology, professional services |
| Braveheart Bio | San Francisco, CA | Therapeutics for hypertrophic cardiomyopathy and related conditions |
| Ab Studio | Hayward, CA | Antibody humanization and optimization service |
| American Qualex | , | Website down Apr 2023 - Aug 2023 |
| , | Renamed Cytonome, Jul 2003 | |
| Liquidia | Morrisville, NC | Precision-Sized Drug Molecules |
| Sonoma Pharmaceuticals | Boulder, CO | Small Molecule Anti-Infectives |
| Kurome Therapeutics | , | Website redirecting to real estate group, Jul 2025 |
| Tosk | Mountain View, CA | Small Molecules for Cancer |
| Dance Biopharm | , | Renamed Aerami Therapeutics, Sep 2019 |
| Serif Biomedicines | Cambridge, MA | Non-Viral Gene Therapy Delivery |
| GlobeImmune | , | Terminated lease on HQ. Effectively done, Nov 2016 |
| Dogma Therapeutics | , | Product acquired by AstraZeneca, Sep 2020; Residential address |
| ResearchDx | Irvine, CA | Diagnostics |
| Terray Therapeutics | Monrovia, CA | Spatially encoded screening and optimization platform |
| Mestag Therapeutics | Cambridge, UK | Fibroblast Biology for Antibody Discovery |
| SineuGene | Beijing, China | Gene Therapy |
| Therachon | , | Bought by Pfizer, Jul 2019, $340M + $470M milestones |
| Boan Biotech | Singapore, Singapore | Biosimilar Antibodies |
| Validus Pharmaceuticals | Parsippany, NJ | Acquired, reformulated generics |
| Gilero | Durham, NC | Medical device design & development, drug delivery systems design & development, 510k FDA, testing, contract manufacturing |
| Generate Biomedicines | Somerville, MA | Machine Learning for Therapeutic Protein Design |
 |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| GSK | Wavre, Belgium | Small Molecules, Vaccines, Biologics |
| Indee Labs | Berkeley, CA | Gene Delivery Technology |
| COUR Pharmaceuticals | Skokie, IL | Nanoparticles |
| Regentys | , | Acquired by Generex, Jan 2019 |
| Providence Medical Technology | Pleasanton, CA | Spinal fusion |
| Anpac Bio | , | Renamed Fresh2, May 2023 |
| , | Website down Sep 2025 - Dec 2025 | |
| Rodin Therapeutics | , | Acquired by Alkermes, Nov 2019, up to $950M |
| Neurogeneration | , | Phase 1 after 15 years; Website password protected Aug 2020 - Oct 2020 |
| SciAn Services | Toronto, ON | Clinical Research, Trial Data Management |
| Bioasis Technologies | , | Closing down Jun 2023 |
| GT Biopharma | San Francisco, CA | Antioxidant Therapeutics, Antibodies |
| Alteron Therapeutics | Kalamazoo, MI | TDP-43 Inhibitors |
| Heraeus Medical | Wehrheim, Germany | Medical Devices |
| Emergent BioSolutions | Winnipeg, MB | Biologics, Contract Manufacturing, Biodefense |
| Mage Biologics | , | No website Jul 2021 - Jul 2024 |
| TocopheRx | , | Gone before 2019 |
| DynPort Vaccines | Falls Church, VA | Vaccines, Biodefense |
| CorMatrix | , | Renamed CorVivo, Jun 2025 |
| numares | Regensburg, Germany | Clinical Diagnostics |
| Oxford Pharmaceuticals | Birmingham, AL | Formulation & Packaging |
| Biostage | , | Renamed Harvard Apparatus Regenerative Technology, Jul 2023; fka Harvard Apparatus Regenerative Technology |
| Revixia | , | Website down Jan 2023 - Jul 2023; Inside ATAI for now |
| Novometrics | , | Dissolved Dec 2019 |
| UgenTec | , | Merged with Seven Bridges Genomics & PieranDx to become Velsera, Jan 2023 |
| Vivoryon Therapeutics | Halle, Germany | Small Molecules |
| , | Shut down Jul 2026; aka Integrity Implants | |
| , | Acquired by MannKind, Oct 2025, $296M | |
| Hematech | , | Acquired by Sanford Health, Jan, 2013, became Sanford Applied Biosciences |
| Ichnos Glenmark Innovation | New York, NY | Bispecific Antibodies |
| AegisCN | , | No website, May 2020 - Nov 2023 |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| Vivex Biologics | Atlanta, GA | Tissues |
| TeselaGen Biotechnology | Portola Valley, CA | AI-enabled software platform for designing, building, and optimizing biological and biochemical products. |
| ChemioCare | , | Renamed Starton Therapeutics, Dec 2019 |
| FutureChem | Seoul, Korea | PET agents, Radiopharmaceuticals |
| |
Tbilisi, Georgia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Korsana Biosciences | Waltham, MA | Neurodegenerative Therapies |
| Meribel Pharma Group | Solna, Sweden | Contract Manufacturing |
| CAPP Medical | , | Acquired by Roche, Apr 2015 |
| AutoTissue | Berlin, Germany | Cardiovascular Tissue Engineering |
| Meabco | , | |
| PENTAX Medical | Tokyo, Japan | Medical Devices |
| Calydon | , | Acquired by Cell Genesys Aug 2001, $17.4M stock |
| Bellerophon Therapeutics | , | Liquidated, Oct 2023 |
| NeoSeq | , | Website down May 2021 - Aug 2021 |
| SensaPharm | , | Website gone, Jan 2020 - Jan 2021 |
| Rexahn Pharmaceuticals | , | Merged with Ocuphire Pharma, Nov 2020 |
| ZOETIC Pharmaceuticals | , | Website Gone Jan 2019 |
| EpiPM Therapeutics | , | Renamed Praxis Precision Medicines, Oct 2016 |
| Lachman Consultants | Westbury, NY | Regulatory Consulting |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Zycos | , | Acquired by MGI Pharma, Sep 2004, $50M |
| Sotera Digital Health | Carlsbad, CA | Vital signs monitoring devices |
| Seracare Life Sciences | Milford, MA | Biologic products for research |
| Atro Medical | Nijmegen, Netherlands | Meniscus Prosthesis |
| InterVivo | , | Renamed Transpharmation, Jun 2025 |
| Auritec Pharmaceuticals | , | Business filings 1.5 years late May 2024, no news since 2018 |
| Kuroki Consulting | , | Shut down 2020 |
| Omniscient Neurotechnology | Sydney, Australia | Software solutions to connect pioneers in neurosurgery, neurology, and neuroscience with subject-specific brain analytics. |
| Compass Biotechnology | , | Delinquent in CO, 2012 |
| PIN Pharma | , | Website taken over Jun 2023; Website down Feb 2023 - Apr 2023 |
| RapidTrials | , | Pivoted to staffing, 2017 |
| Solirna Biosciences | , | Ceased operations in 2010. Owned by Genesis R&D which ran out of money |
| Commit Biologics | Aarhus, Denmark | Single-domain Antibodies |
| ADSM-Synchro Medical | , | Acquired by Tyber Medical, Feb 2023 |
| Cabrellis Pharmaceuticals | , | Acquired by Pharmion, Nov 2006 |
| uFluidix | Toronto, ON | Point of care diagnostics and cartridges |
| Origene | Wuxi, China | Human cDNA Library, Monoclonal Antibodies |
| GenEndeavor | Hayward, CA | Diagnostics |
| Chiron Behring Vaccines | , | Bought by Bharat Biotech, Feb 2019 |
| Sebra | Tucson, AZ | Tube Sealer |
| Alpha Fusion | Tokyo, Japan | Radiopharmaceuticals |
| Bayer | Bergkamen, Germany | Small Molecules |
| NMD Pharma | Aarhus , Denmark | Small Molecule Drug Discovery |
| Renascent Biosciences | , | Website down Sep 2021 - Jan 2022 |
| Urogenix | , | Acquired by Astellas |
| Ultragenyx Pharmaceutical | Bedford, MA | Small Molecules, Biologics, Gene Therapy, mRNA, Antisense Oligo |
| Dezima Pharma | , | Acquired by Amgen Sep 2015, $300M+$1.2B milestones |
| LoQus23 Therapeutics | Cambridge, UK | Oral Small Molecules |
| arGEN-X | , | Older name for Argenx |
| SMS-oncology | , | Merged with Cato Research, Oct 2019 |
| Signet Therapeutics | Shenzhen, China | Organoid Model Drug Discovery, AI |
| Hypoxygen | Frederick , MD | Hypoxia workstations, gloveboxes, low oxygen incubators, carbon dioxide chambers for precise atmospheric control in cell bio and physiological research |
| CellFiber | Tokyo, Japan | Fiber Culturing Equipment |
| Niche Biomedical | , | Renamed Aneuvo, Dec 2021 |
| Regen BioPharma | , | Website gone Sep 2025; Filings late Mar 2023 - Aug 2025 |
| Avantis Medical Systems | , | Shut down Aug 2019, IP assets acquired by PSIP LLC Jul 2019 |
| Biolipox | , | Bought by Orexo, €94M, Oct 2007 |
| Graybug | , | Now Graybug Vision |
| Anew Medical | , | Renamed Klotho Neurosciences, Sep 2024 |
| Actinobac Biomed | , | Website under construction, Sep 2021 - Jun 2022 |
| MicroSpec | Peterborough, NH | Medical Extrusions, Catheters |
| Zoll | Broomfield, CO | Medical Devices, Defibrillators |
| SaponiQx | Lexington, MA | Saponin Based Vaccine Adjuvants |
| Ark Therapeutics | , | Attempted to sell business, instead only sold parts |
| cmbio | Germantown, MD | Omics, Bioinformatics, Software Platforms |
| EXPUTEC | , | Acquired by Korber Group, Jun 2020 |
| Agencourt Bioscience | , | Now Beckman Coulter Genomics |
| Biocorp | Issoire, France | Medical Devices |
| Nastech Pharmaceutical | , | Changed name to mdRNA, Nov 2007 |
| Foresee Pharmaceuticals | Newark, DE | Drug Delivery tech |
| Bearpac Medical | , | Website down Feb 2021 - May 2021 |
| Akesis Pharmaceuticals | , | Bankrupt 2009, closed 2013 |
| Boryung | , | Linkedin page is an homage, Mar 2025 |
| Caris Life Sciences | Irving, TX | Diagnostics |
| XaTek | , | No news 2021 - Feb 2025 |
| Sciengenix Laboratory | , | Website gone Nov 2022 |
| Syqe Medical | Tel Aviv, Israel | Inhaler for Medicinal Plants |
| KVK Tech | Newtown, PA | Generics |
| enEvolv | , | Acquired by Zymergen, Mar 2020 |
| Spectrus | Beverly, MA | End-to-end mass spec CRO with project consulting, method design, sample processing and data analysis |
| Chem-Tech | , | Bought by Neogen, Jan 2014 |
| Certara | Radnor, PA | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| IMV | , | Assets acquired by BioVaxys, Feb 2024; fka Immunovaccine |
| VRG Therapeutics | Leiden, Netherlands | Ai Drug Discovery Platform |
| Longeveron | Miami, FL | Stem Cells to combat aging |
| Alfama | , | Merged into Proterris, May 2017 |
| Persys Medical | , | Acquired by Safeguard Medical, Jun 2021 |
| Metronomia | Munich, Germany | Consulting & Data Management |
| PHusis Therapeutics | , | No news 2014 - Jul 2024; Residential Address Aug 2022 |
 |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Adaptive TCR | , | Changed name to Adaptive Biotechnologies, Jan 2012 |
| Accell Clinical Research | Bucharest, Romania | Clinical Research |
| Onyx Pharmaceuticals | , | Bought by Amgen, Aug 2013, $10.4B |
| Korro Bio | Cambridge, MA | RNA-editing Drugs |
| Synergistix Biotech | , | Dissolved Dec 2003 |
| Uriach | Barcelona, Spain | Small Molecules, OTC |
| Merck | Lansdale, PA | Small Molecules, Vaccines, Biologics |
| Inflection Biosciences | Dublin, Ireland | Small Molecule Discovery |
| Treeway | Tilburg, Netherlands | Small Molecules, Gene Therapy |
| Addimmune | Rockville, MD | HIV Gene Therapy |
| Telix Pharmaceuticals | Herstal, Belgium | Radio immunotherapy |
| SmartZyme BioPharma | , | Website gone Jan 2021 |
| Worldwide Clinical Trials | Kharkov, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Cynvec | , | Website being update Jan 2023 - May 2023 |
| Pilot Therapeutics | , | Effectively defunct late 2003 |
| SteriTech | Surrey, UK | Process Equipment |
| , | No news Jan 2021 - Jan 2026 | |
| BASE Pharma | , | Seem to be part of Getz Healthcare now |
| Prometic Bioseparations | , | Renamed Astrea Bioseparations |
| NxGen MDx | Grand Rapids, MI | Fetal Genetic Screening |
| Simplify Clinical Trials | , | Website down Aug 2024; No business Filings 2023-2024 |
| Senti Biosciences | South SF, CA | Gene Circuits; Cell & Gene Therapies |
| Phoenicia Biosciences | , | Seems like baloney company. SBIR |
| Viridian Pharma | , | Acquired by Martindale Pharma, Jul 2016 |
| Bio-Rad | Richmond, CA | Research & Diagnostic Products |
| , | Acquired by Alcon, Sep 2025 | |
| Praxis Life Sciences | , | Acquired by Treximo, Mar 2019 |
| Entelos | , | Bankrupt |
| ImmunoSite Technologies | , | Website taken over Feb 2024 |
| GRAIL | Menlo Park, CA | Cancer diagnostics |
| , | Acquired by BICO, Aug 2021, $15M | |
| Solsys Medical | , | Acquired by Misonix, Sep 2019, $97M stock; fka Soluble Systems |
| Retrotope Pharmaceuticals | , | Filings late Dec 2022 - May 2025; No info 2021 May 2025 |
| NNS Clinical Research | , | Gone |
| Neurotrope | , | Renamed Synaptogenix, Dec 2020 |
| Preora Diagnostics | , | Renamed Preora Healthcare, Oct 2017 |
| Abbey Pharmaceuticals | , | Acadia spinout. No info since 2006 founding. Presume defunct |
| Kogenix | , | Merged with Klogene, Dec 2017 |
| Nubiyota | Guelph, ON | Microbiome therapeutics platform |
| Lannett | Trevose, PA | Generic Small Molecules |
| Calistoga Pharmaceuticals | , | Bought by Gilead, Feb 2011, $375M + $125Milestones |
| Luminex | , | Acquired by Diasorin, Apr 2021, $1.8B |
| TSRL Inc | Ann Arbor, MI | Advisory Services |
| Avexxin | , | Rebranded as Coegin Pharma |
| BRT Laboratories | , | Seem to be part of DNA Diagnostics Center, Nov 2019 |
| Aliri | Colorado Springs, CO | Contract Mass Spec |
| Safecor Medical | , | Shut down Apr 2021 |
| Sapient Discovery | , | Shut down, Jan 2018 |
| Johnson and Johnson | New Brunswick, NJ | Consumer Products |
| Mantra Bio | , | Website down Aug 2024 - Mar 2025 |
| SixOne Solutions | , | Website Gone, Feb 2017 - Mar 2017; 2013 SBIR |
| Cortria | , | Website down Feb 2025 - Jun 2025 |
| STC-Stem Cell Treatment & Research Institute (STRI) | Seoul, Korea | Stem Cell Treatments |
| Bionoxx | Seongnam, Korea | Tumor-targeting Antigen |
| Ravata Solutions | , | Website down Feb 2025 - Jun 2025 |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| iLeadBMS | Hwaseong, Korea | Small Molecules |
| GlycoSolutions | , | Closed Aug 2015 |
| CO.DON | Teltow, Germany | Cell Therapies |
| Synthorx | , | Acquired by Sanofi, Jan 2020, $2.5B |
| Brain Scientific | , | Website down Sep 2023 - Mar 2024 |
| Noble Life Sciences | Woodbine, MD | Preclinical CRO, Drug, Vaccine & Devices, GLP and non-GLP, Small & Large Animals, FDA, OLAW, AAALAC |
| |
Tonneins, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Adams Clinical | Watertown, MA | Clinical Facility |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Rockfield Medical Devices | Galway, Ireland | Tube & Pump Feeding Technology |
| Redwood Pharma | , | Website down Dec 2024 - Apr 2025 |
| Yao Pharma | Chongqing, China | APIs, Generics |
| ATS Medical | , | Bought by Medtronic, Apr 2010, $370M |
| Origami Therapeutics | San Diego , CA | Small Molecules for Genetic Diseases |
| Chemify | Glasgow, UK | Robotics, AI, Chemistry, Chemputers |
| Flowonix Medical | Hackettstown, NJ | Spinal drug delivery pump |
| Arbovax | , | Gone |
| Zenas BioPharma | Waltham, MA | Immune-Based Therapies |
| West Pharma | Waterford, Ireland | Pharmaceutical Supplier |
| EAG Laboratories | Toulouse, France | Analytical & Synthesis Services |
| Ratiopharm | Ulm, Germany | Generic Small Molecules |
| Cosyne Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Medacta | Castel San Pietro, Switzerland | Orthopedic Implants |
| Quell Therapeutics | London, UK | Treg cell therapies |
| Tyrian Diagnostics | , | Gone 2012 |
| Ankon Technologies | Wuhan, China | Medical Devices |
| ApoCell | , | Acquired by Precision for Medicine, Jul 2019 |
| In Veritas Medical Diagnostics | , | Shell company |
| Intelligenome | Houston, TX | CRISPR Diagnostics |
| Qrumpharma | , | Acquired by MannKind, Dec 2020 |
| Fornix Biosciences | , | Acquired by skiing company in reverse merger, Dec 2013 |
| Bacainn Therapeutics | , | Now part of Adiso Therapeutics |
| KaloCyte | Baltimore, MD | Artificial Red Blood Cell |
| Impleo Medical | , | CEO Founder Owner gone but still on website |
| GlycoMark | , | Website down Jun 2023 - Dec 2023 |
| TB-Stopper | , | Website hijacked Oct 2020 |
| Hemispherx Biopharma | , | Renamed AIM ImmunoTech, Aug 2019 |
| PDTx | , | Merged with Ovation.io, Sep 2024 |
| Trinity Biotech | Jamestown, NY | Diagnostics |
| Kalila Medical | , | Acquired by Abbott, Feb 2016 |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| InteRNA Technologies | , | Shut down Mar 2023 |
| Capella Bioscience | , | Merged into Centessa Pharmaceticals |
| Aptose Biosciences | San Diego, CA | Cancer Drugs |
| DxTerity | Torrance, CA | Genomic Testing |
| Apollo Endosurgery | , | Acquired by Boston Scientific, Apr 2023, $615M |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Skyline Biosciences | , | Subsumed into Paragon Biosciences |
| Otonomy | , | Laid off all employees, Dec 2022 |
| Supira Medical | Los Gatos, CA | Low-profile, high-flow percutaneous ventricular assist device |
| Soin Therapeutics | , | Acquired by JanOne, Sep 2022 |
| Physical Sciences | Andover, MA | Retinal Imaging |
| Concordia International | , | Renamed Advanz Pharma, Oct 2018 |
| Repligen | Waltham, MA | Protein Manufacturing |
| Rubik Therapeutics | , | Website down Nov 2024 - May 2025 |
| Teva | Petah Tikva, Israel | Small Molecules, Biologics |
| Miracogen | Shanghai, China | Antibody-drug conjugates |
| Spirosure | , | Acquired by Caire, Jun 2020; fka Spirometrix |
| OTR Therapeutics | Shanghai, China | Treatments for immunology & inflammation, oncology |
| Puma Biotechnology | Los Angeles, CA | Acquisition & Development of cancer therapies |
| Moderna Therapeutics | Harwell, UK | RNA Therapies |
 |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| CSL Behring | Bradley, IL | Biologics |
| Penrose TherapeuTx | , | Website down Aug 2023 - Feb 2024 |
| SEQENS | Bourgoin, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Five3 Genomics | , | Website redirecting to Nantoomics, Nov 2019 |
| TRIFARMA | Rozzano, Italy | APIs |
| 4SC-Discovery | , | Sold to BioNTech Small Molecules, Apr 2016 |
| Nexus Therapeutics | , | Acquired by Transport Pharmaceuticals, Aug 2006 |
| Synthetica Bio | , | Renamed Ryght, Nov 2023 |
| iCeutica | , | Seems gone, Jan 2022 |
| Acorn Biomedical | , | Not registered as business in CA Mar 2020 - Apr 2020 |
| Casper Pharmaceuticals | East Brunswick , NJ | Specialty Pharmaceuticals |
| Saama Technologies | Campbell, CA | Clinical Trial Analytics |
| Iris Medicine | Berkeley, CA | Small Binding RNA |
| Avidea Technologies | , | Acquired by Vaccitech, Dec 2021 |
| RND Group | , | Acquired by Gener8, Dec 2021 |
| Science | Alameda, CA | Retinal Implants, Medical Technology |
| Arista Biologicals | , | Acquired by Fortis Life Sciences, Feb 2022 |
| , | Main employees gone for months as of Nov 2025 | |
| Acella Pharmaceuticals | Alpharetta, GA | Generics |
| BioMedical Enterprises | , | Bought by DePuy Synthes, May 2016 |
| Transparency Life Sciences | , | Renamed Drumroll Health |
| Analiza | Cleveland, OH | Physicochemical Services |
| Excelsyn | , | Bought by AMRI |
| Kala Pharmaceuticals | , | Renamed KALA BIO |
| Midlothian Labs | , | Acquired by Hi-Tech Pharmacal, Dec 2007 |
| , | Winding down Apr 2026 | |
| Berkshire Sterile Manufacturing | , | Acquired by Sharp, Oct 2023 |
| GCP ClinPlus | Beijing, China | Clinical Research |
| Diffinity Genomics | , | Acquired by Chiral Technologies, Aug 2015 |
| Cloudbyz | Warrenville, IL | Clinical Trial Management Software |
| Bioiberica | Palafolls, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| Carbogen Amcis | Manchester, UK | Drug Development & Commercialization |
| SiDx | , | Website down Oct 2022 - Apr 2023 |
| Abcuro | Newton, MA | T Cell Therapy, Antibodies |
| Interpreta | , | Website down Feb 2024 - Jul 2024 |
| Veristat | Brighton, UK | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Topadur Pharma | Schlieren, Switzerland | Compounds Targeting cGMP-Enzyme Regulation System |
| , | Acquired by Paradigm Health, Jan 2023 | |
| Engrail Therapeutics | San Diego, CA | Treatments for Life-Limiting Diseases |
| Saptalis Pharmaceuticals | Hauppauge, NY | Complex generics, difficult to formulate dosage forms and novel drug delivery systems |
| Potrero Medical | , | Renamed Accuryn, Feb 2024 |
| Intraop Medical | Sunnyvale, CA | Radiation therapy during surgery |
| Mentice | Gothenburg, Sweden | Endovascular Simulators |
| ErVaccine | , | Renamed ErVimmune, Oct 2023 |
| Proximity Biosciences | , | Website down Jul 2021 - Oct 2021 |
| , | ||
| ProBioGen | Berlin, Germany | Therapeutic Proteins, Viral Vaccines, Contract Development and Manufacturing, Immunogenicity Testing |
| NomoCan Pharmaceuticals | , | No progress 2014-2024 |
| Allosteros Therapeutics | , | No website Dec 2018 - Dec 2019 |
| CQ Medical | Orange City, IA | Positioning, Radiation Devices |
| Gyrasol Technologies | , | Website gone, marked as closed on google, emails bouncing |
| Blue Ridge BioSciences | , | Employee who left 2.5 yrs ago still on website Apr 2021 |
| Dongfang Biotech | Beijing, China | Antibody Therapies |
| Insight Pharmaceuticals | , | Acquired by Prestige Brands, Apr 2014, $650M |
| Xel Herbaceuticals | , | Renamed Xel Pharmaceuticals |
| DMK Pharmaceuticals | , | Bankruptcy, Feb 2024; Merged with Adamis, May 2023 |
| Neotract | , | Acquired by Teleflex, Sep 2017, $1.1B |
| Angstrom Pharmaceuticals | , | Website disappeared, Jan 2016 no info |
| Microsure | Son, Netherlands | Surgical Robots |
| Matica Biotechnology | College Station, TX | CDMO for Cell, Gene, Vaccines & Viral Therapies |
| Horizon Discovery | , | Acquired by Perkin Elmer, Oct 2020, $383M |
| SVBio | , | Changed name to Lifecode |
| Gavilán Biodesign | , | Renamed Ten63 Therapeutics, 2020 |
| Enzene Biosciences | Pune, India | Biosimilars, peptides |
| , | No news 2019 - Sep 2025 | |
| NeoProgen | , | Website down Aug 2022 - Jan 2023 |
| ATXA Therapeutics | Dublin, Ireland | Cardiopulmonary Treatments |
| ChemGenes | Wilmington, MA | DNA / RNA synthesis |
| Streck | La Vista, NE | QC & Diagnostic Products |
| Abalone Bio | Emeryville, CA | Antibody Therapies |
| RSIP Vision | San Jose, CA | Image analysis algorithms |
| Xenetic Biosciences | Framingham, MA | Biologic drugs, novel oncology therapeutics and vaccinations |
| Lincoln pharmaceuticals | Ahmedabad, India | Generics |
| POINT Biopharma | , | Acquired by Eli Lilly, Dec 2023, $1.4B |
| Oncologie | , | Renamed OncXerna, Sep 2020 |
| AMS UK | , | Website down Apr 2022 - Aug 2022 |
| Nereid Therapeutics | Boston, MA | Small molecules that can modulate protein interactions found in disease states |
| Ion Dx | Monterey, CA | Ion Mobility Spectrometer, Associated Services |
| Progentec Diagnostics | Oklahoma City, OK | Diagnostics |
| Heraeus Medical | Zhaoyuan, China | Medical Devices |
| , | Acquired by Sebia, Dec 2022 | |
| Therapixel | Nice, France | Artificial Intelligence for Medical Imaging |
| Compass Neurosciences | , | Renamed Ceretype Neuromedicine, Feb 2020 |
| Stratagene | , | Acquired by Agilent, Apr 2007, $246M |
| EastCoast Bio | , | Acquired by Medic Biochemica, Jun 2020 |
| AmProtein | , | Presumed Gone |
| 3PBIOVIAN | Boston, MA | CDMO - viral vectors, plasmids, proteins |
| Validation Professionals | , | Website crazy outdated, Aug 2024 |
| SaluMedica | , | Website Gone Jul 2015 |
| Acta Vascular | , | Acquired by CardioVasc, Apr 2007 |
| Currax Pharmaceuticals | Brentwood, TN | Small Molecules, Specialty, Generics |
| Aureka Biotechnologies | Laguna Hills, CA | Digitalizing Therapeutic Discovery |
| Nonagen Therapeutics | London, UK | Cancer Therapies |
| Autotac Bio | Seoul, Korea | Autophagy-targeting chimeric molecules |
| PharmaRoth Labs | , | Reincarnation of Fero Industries. No website, stock still traded as of Jul 2014 |
| , | Renamed Kapadi, Nov 2025 | |
| Raven Biotechnologies | , | Acquired by MacroGenics Jul 2008 |
| Integrated Nano-Technologies | , | Bankrupt Mar 2023 |
| Incipio Devices | Huntington, IN | Orthopedic Devices, Contract Manufacturing |
| Imperative Care | Campbell, CA | Large Diameter Catheters for stroke care |
| Ho’ola Therapeutics | , | |
| Pro-Pharmaceuticals | , | Changed name to Galectin Therapeutics |
| Control Medical Technology | , | Website down Jan 2025, no FL busienss registration, no employees |
| Amneal Pharmaceuticals | Branchburg, NJ | Generic Small Molecules |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Viatris (2) | Shanghai, China | Small Molecules, Generics |
| Piramal | Aurora, ON | CDMO |
| Axis Therapeutics | , | Website down Dec 2022 - Apr 2023; JV between Athenex & Xiangxue Life Sciences |
| ChemCon | Freiburg, Germany | Contract chemical R&D; small molecule contract manufacturing |
| Gennova Bio | Pune, India | mRNA vaccine |
| Integra LifeSciences | Tullamore, Ireland | Medical Devices |
| Silarus Therapeutics | , | Shut down Dec 2020 |
| Laurus Labs | Hyderabad, India | API manufacturing |
| Alanex | , | Acquired by Agouron, Apr 1997 |
| PhysioCue | , | Website down Mar 2022 - Oct 2022 |
| TE Connectivity | Berwyn, PA | Medical Devices |
| Celmed BioSciences | , | Acquired by Kiadis Pharma, Dec 2006 |
| Nightstar Therapeutics | , | Acquired by Biogen, Jun 2019, $800M; aka NightstaRx |
| Hyseg Pharmaceuticals | , | Acquired by ARCA Biopharma, Jan 2009 |
| Biokeys Pharmaceuticals | , | Changed name to ADVENTRX Pharmaceuticals Jun 2003 |
| Cardeas Pharma | , | Gone, 2017 |
| Cognitive Pharmaceuticals | , | Merged with Mithridon, Jun 2008 |
| Raidium | Aubervilliers, France | Foundation Model for precision medicine in radiology |
| , | Acquired by AbbVie, Aug 2025 | |
| Zocere | , | Website down Dec 2022 - Apr 2023 |
| ChironWells | , | Website down Dec 2023 - Jul 2024 |
| Amp Orthopedics | , | Shut down, 2012 |
| Spineart | Plan-Les-Ouates, Switzerland | Spinal Implants |
| RiboX Therapeutics | Shanghai, China | Circular RNA |
| Cambrian Bio | New York, NY | Small Molecules |
| Organicell | , | Renamed Zeo Scientific, Mar 2024 |
| Resonetics | Nashua, NH | Contract Medical Device Manufacturing & Development |
| SapVax | , | Website down Feb 2023 - Jun 2023 |
| ActoBio Therapeutics | , | Brought into Precigen |
| HealthPoint Bio | , | Bought by Smith & Nephew |
| PanXome | , | Website down Sep 2021 - Jan 2022 |
| Revitope Oncology | Amesbury, MA | Antibody conjugated to a peptide containing a protease cleavable site |
| MedPharm | Durham, NC | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Synerlab Group | , | Renamed Meribel Pharma Group, Apr 2025 |
| Icell Kealex Therapeutics | , | Website down Jun 2021 - Sep 2021; Were rebranding as Vaxiqure, Apr 2020, but didn't seem to happen |
| Bayer | Mexico City, Mexico | Small Molecules |
| Tolemy Bio | Cambridge, UK | Cell Biology Simulation |
| , | Acquired by Bausch + Lomb, Jul 2024; fka TearLab | |
| , | Acquired by Azurity Pharmaceuticals, Apr 2025 | |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Werfen | Bedford, MA | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| Cadwell Industries | Kennewick, WA | EEG, EMG, Electrodes, Other Devices |
| Autocam Medical | Plymouth, MA | Precision-Machined Medical Devices, Implants |
| ViraTherapeutics | , | Bought by Boehringer Ingelheim, Sep 2018, $244M |
| Spiral Genetics | , | Acquired by Omicia, Jan 2017 |
| Neovasc | , | Acquired by Shockwave Medical, Apr 2023, $100M |
| Roxall | , | No news 2019 - May 2025 |
| KARL STORZ Endoscopy | Tuttingen, Germany | Endoscopy |
| ProMedDx | , | Acquired by Precision for Medicine, Aug 2019 |
| Escalier Biosciences | , | Website down Jan 2023 - Jul 2023 |
 |
Philadelphia, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Wellinks | New Haven, CT | Portable Nebulizer |
| MANA Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| Scitara | Marlborough, MA | Digital Connectivity for Labs |
| Nashville Biosciences | Nashville, TN | Linked EMR and biospecimens |
| Gifford Bioscience | Birmingham, UK | Preclinical CRO specializing in receptor-ligand interactions. |
| ApoImmune | , | Gone 2014 |
| Deep Apple Therapeutics | San Francisco, CA | Oral small molecule |
| Raqia Therapeutics | , | Renamed Dynamic Cell Therapies, Jun 2022 |
| N2 Biomedical | , | Merged with Precision Medical Coatings, Sep 2021; fka Spire Medical |
| Biosero | San Diego, CA | Laboratory Automation, Liquid-handling |
| AbbVie | Mascot, Australia | Small Molecules, Biologics |
| 908 Devices | Burlington, MA | Pre-Mass spec prep device |
| Ceragenix Pharmaceuticals | , | Bankruptcy |
| INVO Bioscience | , | Merged with NAYA Biosciences, Oct 2024 |
| Vanton Research Laboratory | , | Seems closed, Oct 2021 |
| Indigene Pharmaceuticals | , | Gone 2012 |
| MannKind | Westlake Village, CA | Inhalable Biologics, Gene Therapy |
| Vernay | Suzhou, China | Fluid Control Solutions |
| Genomadix | Kanata, ON | Portable PCR |
| CynapseDx | , | Acquired by Pharmakure, Apr 2021 |
| Numeric Biotech | , | Four listed employees don’t list as a job on LI, Aug 2022 - Oct 2025 |
| Institute for Drug Discovery | , | Gone |
| Delpharm | Boulogne-Billancourt, France | Contract Manufacturing |
| Amnis | , | Acquired by EMD Millipore, Aug 2011 |
| OP2 Drugs | , | Website gone Jan 2020 |
| Apollo Cytokine Research | , | Acquired by Symansis, Jun 2008 |
| Latigo Biotherapeutics | Thousand Oaks, CA | Non-opioid Pain Relief |
| Chesapeake PERL | , | Likely gone. No plans to bring back website. |
| ID Pharma | , | Acquired by I'rom Group |
| Helena Laboratories | Beaumont, TX | Diagnostics, Capillary Electrophoresis |
| Twist Bioscience | Tel Aviv, Israel | Synthetic DNA, genes and libraries |
| BioBoston Consulting | Boston, MA | Quality & Regulatory Consulting |
| |
Dundalk, Ireland | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Sygnature Discovery | Cheshire, UK | Drug Discovery Contract Research |
| Solis Biodyne | Tartu, Estonia | PCR and qPCR reagents |
| Biedermann Motech | Miami , FL | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| SOTIO Biotech | Prague, Czech Republic | Active Cellular Immunotherapy |
| Apic Bio | , | Shut down Jan 2024 |
| NeuroNova | , | Acquired by Newron, Jun 2012 |
| Protara Therapeutics | New York, NY | Cell Therapy |
| Atheromed | , | Acquired by Volcano, May 2014, $115M |
| PeLeMed | Seoul, Korea | Viral and Cancer Drugs |
| Amylon Therapeutics | , | Website down Oct 2023 - Mar 2024; Spun out of ProQR, Sep 2017 |
| Sofie | Dulles, VA | PET Imaging, radiochemical synthesis, radiopharma probes |
| Cutaneous NeuroDiagnostics | , | Renamed CND Life Sciences |
| Datar Cancer Genetics | Nashik, India | Liquid Biopsy Analysis |
| Ovid Therapeutics | Boston, MA | Treatments for rare brain disorders |
| Clinical Research Laboratories | , | Acquired by eurofins, Sep 2018 |
| CRELUX | Gräfelfing, Germany | Drug Discovery Services |
| Maruho Medical | , | Website down Apr 2024 - Aug 2024 |
| Advanced Clinical | Frankfurt, Germany | Clinical Research Organization |
| Med Institute | West Lafayette, IN | Medical Device Testing |
| Protean BioDiagnostics | Orlando, FL | Oncology Services |
| UBC | Lake Mary, FL | Biopharmaceutical Consulting & Services |
| Zai Lab | Taipei, Taiwan | Small Molecules |
| YZY Biopharma | Wuhan, China | Bispecific Antibody |
| Stem Pharm | Fitchburg, WI | Biomaterials supporting stem cell growth |
| Acobiom | Grabels, France | Cancer Treatment Prediction |
| Aixlie Pharmaceuticals | , | No idea what happened |
| BioNTech | Berlin, Germany | mRNA, Vaccines, Biologics |
| Garnet BioTherapeutics | , | Bankrupt May 2011 |
| , | Website down Feb 2025 - Dec 2025 | |
| Pulmobiotics | Barcelona, Spain | Live Biotherapeutics |
| Apellis Pharmaceuticals | Munich, Germany | Cyclic peptide analog |
| NerveVision | , | Website gone Dec 2024; Website down Sep 2024; Not sure if active Feb 2024 |
| Michigan Clinical Research Institute | , | |
| Anogen | Mississauga, ON | Antibodies, ELISA kits, growth factors, lab reagents |
| Immunetics | , | Acquired by Oxford Immunotec, Oct 2016 |
| Kylin Therapeutics | , | Sold |
| Diagnostics Research Group | , | Acquired by IMA Group, Oct 2021 |
| Bio-Rad | Pleasanton, CA | Digital PCR |
| Velox Biosystems | , | Website gone Sep 2021, execs gone |
| AutoMedx | , | Website down May 2021 - Sep 2021 |
| PhagoMed | , | Acquired by BioNTech, Nov 2021 |
| AllTech Medical Systems America | , | Website down Oct 2021 - Mar 2022 |
| , | Renamed BreezeBio, Feb 2026 | |
| Gentium | , | Bought by Jazz Pharmaceuticals, Jan 2014, $1B |
| Dermtreat | , | Renamed Afyx Therapeutics, Sep 2018 |
| Acrivon Therapeutics | Lund, Sweden | Checkpoint Inhibitor |
| Invisio Medical | , | Not registered as business in MA, Nov 2021, CEO has different 'real' job |
| Fonar | Melville, NY | Upright MRI |
| , | Website down May 2025 - Jan 2026 | |
| Certara | St. Louis, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Keystone Heart | , | Merged with Venus Medtech, Dec 2018 |
| Correlogic | , | Assets bought by Vermillion 2011 |
| BeVinced | Amsterdam, Netherlands | Medical Device CRO |
| Aucta Pharmaceuticals | Piscataway, NJ | 505(b)(2) |
| mFluiDx | Oakland, CA | Diagnostics at Primary Care Clinics |
| Protein Design Labs | , | Renamed PDL Biopharma |
| bioLytical Laboratories | Richmond, BC | Rapid Diagnostics |
| Cardiome Pharma | , | Acquired Correvio, took name years later |
| , | CEO left Mar 2024, website still listing him Jan 2026 | |
| Arsenal Medical | Waltham, MA | Therapeutic foam technology |
| Harbor Clinical | Hingham, MA | Clinical Trial Services |
| Alliance Protein Laboratories | , | Acquired by KBI Biopharma, Jun 2017 |
| LUMICKS | Amsterdam, Netherlands | Dynamic Single-Molecule analysis products |
| Niche Generics | Arlesey, UK | Contract Generics |
| Aegea Biotechnologies | , | |
| , | Shut Down Dec 2024 | |
| Protein Polymer Technologies | , | Basically Gone |
| Strides Arcolab | , | Now just Strides |
| LabCentrix | , | fka BioPharm Informatics, seems gone Jul 2019 |
| Lumenis | San Jose, CA | Energy-based medical treatments |
| Carolus Therapeutics | , | Business revoked in CA |
| Selenity Therapeutics | , | Renamed Mycovia Pharmaceuticals |
| Paddock Labs | , | Bought by Perrigo, Jul 2011, $540M |
| Fresenius Kabi | Wilson, NC | Contract Manufacturing |
| Diva Pharmaceuticals | , | Owner transitioned to real estate |
| CV Therapeutics | , | Acquired by Gilead Apr 2009, $1.4B |
| Groton Biosystems | , | Gone before Jun 2015 |
| CO.DON | Leipzig, Germany | Cell Therapies |
| FIMECS | Kanagawa, Japan | RaPPIDS, E3 ligase binders and linker combinations |
| Bionure | , | Reincarnated as Accure Therapeutics, May 2020 |
| Apogent | , | Acquired by Fisher, Aug 2004 |
| HiArc | Merrimack, NH | CDMO specializing in design and development of complex medical instrumentation |
| DLRC Group | Munich, Germany | International consulting group, supporting the Pharma & Biotech community |
| Maine Biotechnology Services | , | Acquired by BBI, Mar 2018 |
| Zion Pharma | Shanghai, China | BBB-penetrating Compounds |
| Aragen Life Sciences | Hyderabad, India | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| BlueSens Gas Sensor | Herten, Germany | Gas Analysis in Bioprocessing |
| AVEO Oncology | Boston, MA | Small Molecules |
| Metabolomics Diagnostics | , | Acquired by Trinity Biotech, Sep 2024 |
| Grey Matter Neurosciences | Toronto, ON | Ultrasound Helmet |
| Quality Agents LLC | Rockville, MD | Provides Validation, QA, QC, and Project Management services for Biotech and Pharma clients. |
| Microfluidics | Westwood, MA | High shear fluid processors |
| SIG Medical | , | Acquired by Zimmer, Sep 2019 |
| Stago | Tianjin, China | Diagnostics |
| AcuraBio | , | Shut down Sep 2023; fka LuinaBio |
| Bowil Biotech | , | Renamed Biovico, Feb 2025 |
| Jina Pharmaceuticals | , | |
| ProMed Molding | Minneapolis, MN | Device component molding, assembly |
| , | Website down Jan 2026 - May 2026 | |
| Synthesize Bio | Seattle, WA | AI-data Generation |
| NextPharma | Limay, France | Contract Research & Development |
| Alaeras | , | Dissolved Jan 2014 |
| Veraptus | , | Website down Apr 2023 - Sep 2023 |
| Medvacon | Sparta, NJ | Quality and Compliance Consulting |
| Laronde | , | Merged with Senda Biosciences to become Sail Biomedicines, Oct 2023 |
| Asentral IRB | , | Acquired by Brany, Dec 2019 |
| Biopharma Group | Winchester, UK | Biopharma Group are a global CDMO who specializes in liquid and drying technologies. |
| Sitec Labs | Navi Mumbai, India | Analytical Bioequivalence |
| Quality Biological | Gaithersburg, MD | Custom and standard cell culture media, buffers, molecular biology reagents, and bacterial media |
| Pandorum Technologies | San Carlos, CA | Tissue Engineering |
| FDAQRC | Cedar Park, TX | Quality & Regulatory Consultants |
| Atopix Therapeutics | , | Bought by Chiesi, 2016 |
| X-Biotix Therapeutics | , | Website down May 2022 |
| Veloxis Pharmaceuticals | Cary, NC | Immunosuppression Therapies |
| PCAsso Diagnostics | , | Website gone, Jul 2015 |
| Pharmazz | Greater Noida , India | Small Molecules |
| Axplora | Chennai, India | API manufacturing |
| Alternative Bio | , | No website Dec 2022 - Jul 2025 |
| Early Is Good | Indianapolis, IN | Multi-Omics Platform |
| SpineX | Northridge, CA | Noninvasive Neuromodulation |
| J.B. Pharma | Mumbai, India | Generic Pharmaceuticals |
| RTI Surgical | , | Renamed Evergen, Dec 2024; Brought back after Bankruptcy; Renamed Surgalign, Jul 2020 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Kanglin Biotechnology | Hangzhou, China | AAV Gene Therapy, Stem Cell Platform |
| Onconetics Pharmaceuticals | , | Website taken over Jul 2021 |
| Abiologics | Cambridge, MA | Synteins |
| Calando Pharmaceuticals | , | Subsidiary of Arrowhead Research, no news since 2011 as of Dec 2019 |
| Brain Health Therapeutics | , | Renamed NapticBio, Jan 2018 |
| Baebies | Durham, NC | Newborn Diagnostic Device |
| Heidelberg Pharma | Ladenburg, Germany | Diagnostic and therapeutic products for oncology |
| Predictive Therapeutics | , | Renamed NeoTX |
| Cellipont Bioservices | The Woodlands, TX | Cell Therapy CDMO |
| Thermo Fisher | Guilford, CT | Molecular Biology & Biotech Lab Products |
| Buffalo Biolabs | , | Website hijacked Jun 2023 - Aug 2023 |
| Ablacon | , | Shut down Mar 2024 |
| Advanced Technologies for Novel Therapeutics | , | Website being updated Jun 2015-Dec 2019 |
| Travecta Therapeutics | , | Website down Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| California Neuroscience Research | , | Website down Jul 2022 - Nov 2022 |
| Novonesis | Paraná, Brazil | Enzymes |
| , | Acquired by BioNTech, Dec 2025, $1.2B | |
| Patheon | Florence, SC | Contract Manufacturing and Development |
| Hyku Biosciences | Burlington, MA | Chemoproteomics platform covalently targeting ligandable amino acids |
| NAMSA | Seoul, Korea | Medical Research Organization - Medical Devices |
| Chord Therapeutics | , | Acquired by Merck KgAA, Dec 2021 |
| oncomed manufacturing | Brno, Czech Republic | Contract Manufacturing |
| Humeltis | , | Website empty Sep 2024 - Feb 2025 |
| NeuroPn Therapeutics | , | Website down Jan 2025 - Jun 2025 |
| Polyplus Transfection | , | Acquired by Sartorious, Sep 2023, €2.4B |
| MC3 Cardiopulmonary | , | Acquired by Medtronic, Mar 2024 |
| Pipex Pharmaceuticals | , | Changed name to Sheffield Pharmaceuticals upon reverse merging with them, 2006 |
| Carnot BioSciences | , | Website gone Jan 2023; Spun out of SmartZyme, empty website Aug 2019 - Dec 2022 |
| Amring Pharmaceuticals | , | Acquired by Nordic Pharma, Mar 2024 |
| Adaptiiv Medical Technologies | Halifax, NS | Medical Device Design Software |
| ProFound Therapeutics | Cambridge, MA | Protein Target Discovery |
| Clarivate | London, UK | Vascularized organoids |
| N-of-One | , | Acquired by Qiagen, Jan 2019 |
| AtheroNova | , | Chapter 11 Bankruptcy Mar 2015, Website gone Jun 2016 |
| Nuclera | Cambridge, UK | Desktop Bioprinting |
| EKR Therapeutics | , | Bought by Cornerstone Therapeutics 2012 |
| Carlsmed | Carlsbad, CA | Surgical Workflow Platform |
| Millipore | Temecula , CA | Purification, Analytic Biologics, Discovery |
| Errant Gene Therapeutics | , | Renamed San Rocco Therapeutics, 2020 |
| Exelead | , | Acquired by Merck KgaA, Jan 2022, now part of Sigma-Aldrich |
| Bioenvision | , | Acquired by Genzyme, Oct 2007, $345M |
| CytoPharm | , | Not sure what happened to them, ex employee declined to answer questions |
| KATO Pharmaceuticals | , | Website down, Employees all gone, Aug 2023 |
| Trilliant Surgical | , | Acquired by DJO, Jan 2021 |
| Aviron | , | Acquired by Medimmune, Dec 2001, $1.5B |
| AltruBio | San Francisco, CA | Antibody Therapeutics |
| Moonlight Bio | Seattle, WA | Cell Therapies focused on T cells |
| Orthoforge | , | Website down Dec 2024 - May 2025 |
| Santa Ana Bio | Alameda, CA | Immunology drug development, biologics |
| Scorpion Therapeutics | , | Assets Acquired by Lilly, Jan 2025 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Nemesis Bioscience | , | Website down Mar 2023 - Dec 2023 |
| EMD Serono | Boston, MA | Biologics |
| , | Website taken over May 2026 | |
| Oxford BioTherapeutics | Oxford, UK | Antibody Therapies |
| Rehabtronics | Edmonton, AB | Physical Rehabilitation Devices |
| , | Acquired by Hologic, Jan 2025, $350M | |
| Neuvivo | Palo Alto, CA | ALS Therapies |
| MedPlast | , | Bought Integer Business & Rebranded as Viant Medical, Jul 2018 |
| Targanta | , | Bought by The Medicines Company |
| Vicuron Pharmaceuticals | , | Acquired by Pfizer (2005) then sold to Durata (2010) |
| Allegiant Health | Deer Park, NY | Contract Manufacturing, Generics |
| Apobiologix | Toronto, ON | Biosimilars |
| Interprotein | Kanagawa, Japan | Highly active modulators for protein-protein interaction targets |
| GlyCart Biotechnology | , | Acquired by Roche, Jul 2005 |
| Talon Therapeutics | , | Bought by Spectrum Pharmaceuticals Jul 2013 |
| Praxgen Pharmaceuticals | Monmouth Junction, NJ | Generics |
| , | Renamed Ohio Clinical Trials, Mar 2026 | |
| NephroGenex | , | Filed Chapter 11 Bankruptcy, May 2016; Site gone Jul 2018 |
| Astarte Biologics | , | Renamed Cellero, May 2020 |
| AEYE Health | New York, NY | Diabetic Eye Exam |
| Bio-Detail | , | Website gone Feb 2023 |
| Gannex Pharma | , | Website down Apr 2025 - Sep 2025 |
| Scaled Biolabs | , | Website gone Oct 2022; One co-Founder moved on Feb 2020 |
| Coulter Pharmaceutical | , | Bought by Corixa, Oct 2000 |
| Bioness | , | Acquired by Bioventus, Mar 2021, $45M + $65M milestones |
| IZI Medical | Owings Mills, MD | Bone Cement, Imaging Markers, Surgical Needles |
| Pamlico BioPharma | , | Gone as of Jan 2019 |
| STA Pharmaceutical | San Diego, CA | API manufacturing |
| Edgewise Therapeutics | Boulder, CO | Small Molecules for Musculoskeletal Diseases |
| Vigene Biosciences | , | Acquired by Charles River, Jun 2021, $292M + $57M milestones |
| AdnaGen | , | Main Assets acquired by Qiagen, Mar 2015 |
| Weave Bio | San Francisco, CA | Regulatory Platform |
| Genextropy | , | Gone, site redirecting to Nigerian pharmacy |
| nplex biosciences | , | Renamed Nomic Bio |
| , | Website down Nov 2025 - Apr 2026; Strategic Alts Mar 2023; fka CytRx | |
| AGADA Biosciences | Halifax, NS | Tissue Collection, Clinical Services |
| LGM Pharma | Irvine, CA | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Mastel Precision | Rapid City, SD | Ophthalmology instruments, diamond knives and toric markers |
| ZSFab | Waltham, MA | 3D printed surgical implants |
| , | Liquidated Jun 2025 | |
| RenovoRx | Mountain View, CA | Catheters |
| Epione Biopharmaceuticals | , | Inactive Jun 2016 |
| Peregrine Pharmaceuticals | , | Pivoted to be CRO, CMO and operates under Avid bioservices now |
| Syngene International | Bangalore, India | Contract Discovery, Biology |
| Orchid Orthopedic Solutions | Arab, AL | Contract Medical Device Work |
| GenePath Diagnostics | Ann Arbor, MI | Molecular Diagnostics |
| Nabi Biopharmaceuticals | , | Merged with Biota Holdings 2012 |
| Ultrabio Technologies | , | Shut down Jul 2022 |
| Galenica | , | Spun out health and beauty assets and became Vifor Pharma, Apr 2017 |
| AngioDynamics | Amsterdam, Netherlands | Array of Medical Devices |
| Bespak | King's Lynn, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| Scientia Advisors | , | Website gone Jul 2015 |
| NeuroTransit | , | Behind on taxes in CA |
| , | Website down Aug 2025 - Jan 2026 | |
| BioMarin Pharmaceutical | Mexico City, Mexico | Biologics |
| Holloway America | Springfield, MO | Vessels, Tanks |
| , | Reverse merged with Crypto Mining company, May 2026 | |
| Genefluidics | , | Website down Jan 2025 - Jul 2025 |
| algorithmRx | , | Now Venebio |
| Valeritas | , | Acquired by Zealand Pharma, Feb 2020, $23M |
| Advanced Brain Monitoring | Carlsbad, CA | EEG headsets, physiological monitoring systems, software |
| Facet Technologies | , | Renamed Facet Medical Technologies |
| SciSafe | , | Sold for $73M Nov 2024; Acquired by Biolife Solutions, Sep 2020 |
| Corium | Boston, MA | Transdermal Generics, Consumer Products |
| Gradalis | Carrollton, TX | Cancer immunotherapy, RNAi |
| Bioneer | Oakland, CA | Protein Synthesis Equipment & Reagents |
| AlphaPharm | , | Acquired by Mylan, 2007 |
| Cubist Pharmaceuticals | , | Bought by Merck Jan 2015 |
| Refeyn | Oxford , UK | Mass Photometry |
| PIC Therapeutics | Natick, MA | Modulating Oncology Translation to Improve Cancer Outcomes |
| , | Website down Jan 2026 - May 2026 | |
| ReCode Therapeutics | Menlo Park, CA | Nucleic Acid Therapeutic Delivery |
| Avalign Technologies | Schaumburg, IL | Orthopedics & Surgical |
| Davol | , | Acquired by Bard, 1980 |
| Imris, Deerfield Imaging | Chaska, MN | Image Guided Therapy Solutions |
| Elucida Oncology | , | Shut Down Jul 2024 |
| Alliqua | Langhorne, PA | Hydrogels |
| Five Prime Therapeutics | , | Acquired by Amgen, Apr 2021, $1.9B |
| , | Renamed Solario Bio | |
| Vessix Vascular | , | Acquired by Boston Scientific, Nov 2012, $425M |
| Syapse | , | Acquired by N-Power Medicine, Jan 2025 |
| Phase Scientific | Garden Grove, CA | At Home Lipid Panel |
| Sovereign Pharmaceuticals | , | Merged with Capellon, 2001 |
| RITA Medical Systems | , | Bought by AngioDynamics 2007 |
| Haini Pharmaceutical | Shanghai, China | Generics |
| Gandeeva Therapeutics | Burnaby, BC | Drug discovery using cryogenic electron microscopy |
| Cellworks | South SF, CA | Biosimulations |
| Antisense Therapeutics | , | Renamed Percheron Therapeutics, Nov 2023 |
| Ovax | , | Website down Mar 2025 - Aug 2025 |
| Sequana Therapeutics | , | Bought by Arris Pharmaceuticals 1998 |
| Nova in Silico | Lyon, France | in silico Prediction of Drug Efficacy |
| Full Spectrum Genetics | , | Owner is "gone fishing" in Hawaii according to LI; Website down Apr 2022 - May 2022 |
| Myricx Pharma | , | Renamed MyricxBio, Aug 2023 |
| Octeta Therapeutics | , | Renamed Cirius Therapeutics |
| Solvanix | , | Shut down Nov 2023 |
| Brii Biosciences | Shanghai, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Sterling Pharma Solutions | Cramlington, UK | Contract Development & Manufacturing - APIs |
| Corza Medical | Sinking Spring, PA | Surgical Devices |
| Teva | Parisppany, NJ | Small Molecules, Biologics |
| SEQENS | Ecully, France | APIs, Ingredients |
| , | CEO/Founder gone Sep 2025; Website down Feb 2026 - Mar 2026; Residential Address, Dec 2025 | |
| Tribune Therapeutics | Stockholm, Sweden | Therapies targeting CCN protein |
| Nanomedical Diagnostics | , | Renamed Cardea, Jan 2019 |
| Compass Biotechnologies | , | Stock went to zero in 2012, Shell company |
| Trevigen | , | Acquired by Bio-Techne, Sep 2017 |
| BDD Pharma | Newhouse, UK | Development and clinical testing of innovative pharmaceutical products. |
| Genae Associates | , | Acquired by IQVIA |
| MAA Laboratories | Durham, NC | Drug Delivery Technology |
| Sanofi | Frankfurt, Germany | Small Molecules |
| iECURE | Blue Bell, PA | Gene Editing Therapies |
| Innogenix | Amityville, NY | Generics |
| Integer | Trenton, GA | Medical & Surgical Devices |
| Dharma Biomedical | , | Website gone Nov 2022 |
| Stellartech Research | Milpitas, CA | Electronic device development |
| Valocor Therapeutics | , | Acquired by Dermira, Oct 2011 |
| Teleflex Medical | Piestany, Slovakia | Surgical and Medical Devices |
| Cmed | , | Integrated into Aixial Group, May 2023 |
| Tizona Therapeutics | South SF, CA | Immunotherapies |
| Meadowhawk Biolabs | Marlborough, MA | Small & Large Molecule CRO |
| Hyprocell | , | Website down Apr 2022 - Aug 2022 |
| Blansett Pharmacal | , | Gone Jan 2019 |
| Acadia Pharmaceuticals | San Diego, CA | Small Molecules |
| Natco Pharma | Uttarakhand, India | Generics, APIs, Contract Manufacturing |
| ViroCell Biologics | London, UK | CDMO - viral vectors and gene-modified cells |
| Mediar Therapeutics | Boston, MA | Antibody Therapies |
| Endocyte | , | Bought by Novartis, Dec 2018, $2.1B |
| ISM Therapeutics | , | Website Gone, no response from employees |
| Aerocrine | , | Bought by Circassia Pharmaceuticals, May 2015, $219M |
| AqueSys | , | Acquired by Allergan, Oct 2015, $300M |
| BioAtla | San Diego, CA | Conditionally-active Biologics |
| Cell Marque | Rocklin, CA | Antibodies, etc. |
| TeneoBio | , | Acquired by Amgen, Oct 2021, $900M; fka OMT Therapeutics |
| Eli Lilly | Basingstoke, UK | Small Molecules, Biologics |
| Mediwhale | Singapore, Singapore | Non-invasive retina scan-based AI software |
| , | Pivoted to defense contracting, Jan 2026 | |
| Accuronix Therapeutics | , | Website down Sep 2025; No news 2016 - Aug 2025 |
| Rubicon Research | Thane , India | Generics |
| Dow Development Labs | Petaluma, CA | Formulation Development, Clinical Manufacturing, Supplies |
| Biomediq | , | Acquired by ScreenPoint Medical, Jan 2025 |
| VasoRx | San Diego, CA | RNA delivery |
| Santen | Tampere, Finland | Ophthalmics |
| Asinex | Winston-Salem, NC | Small Molecule Library Creation |
| Thermo Fisher | Fremont, CA | Lab Supplies and Equipment |
| Sollis Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| OLS Omni Life Science | Basel, Switzerland | Cell Research Products |
| SoundBite Medical | , | Website down Feb 2025 - Jul 2025 |
| KeraCure | , | Gone 2014 |
| PreciThera | , | Website taken over, Dec 2021 |
| Bimini Health Tech | Plano, TX | Tissue & Cell-Based Regenerative Medicine |
| CRISMO | Germiston, South Africa | Clinical Research Investigator Site Management Organization |
| OncoHost | Binyamina, Israel | Personalized Cancer Diagnostics & Treatment |
| Novalon Pharmaceutical | , | Acquired by Karo Bio Nov 2000 |
| LDR Holdings | , | Bought by Zimmer Biomet, $1B, Jun 2016 |
| Ceterix Orthopaedics | , | Acquired by Smith & Nephew, Jan 2019, $50M + $55M Milestones |
| Texcell | Gronau, Germany | Contract Research |
| Luma Therapeutics | , | Website down Mar 2020 - Jan 2021; fka Illumicure |
| Magnolia Medical Technologies | Seattle, WA | Sepsis Diagnosis Device |
| Presage Biosciences | Seattle, WA | Targeted Tumor Drug Delivery Technology |
| TiGenix | , | Acquired by Takeda, Jul 2018, $630M |
| AI Therapeutics | , | Renamed OrphAI Therapeutics, Sep 2023 |
| Akita Biosciences | Boston, MA | Nasal Drug Delivery |
| Karuna Pharmaceuticals | , | Renamed Karuna Therapeutics |
| Camber Spine | King of Prussia, PA | Spinal Implants |
| KBI Biopharma | Louisville, CO | Contract Development & Manufacturing |
| BioSim Pharmaceuticals | , | Not a registered business in WA, no updates 2015-2022 |
| BEBIG Medical | Berlin, Germany | Radiation Therapy Products |
| Ascentage Pharma | Beijing, China | Small molecule cancer therapeutics |
| SynCo Bio Partners | , | Acquired by Wacker, May 2018 |
| NanoSmart Pharmaceuticals | , | Appear inactive, 2019; fka Target Pharmaceuticals |
| Inscope Medical Solutions | , | Website down Jan 2022 - May 2022 |
| Enesi Pharma | , | Renamed aVaxziPen |
| Arrowhead Pharmaceuticals | Madison, WI | RNAi |
| MediQuest Therapeutics | , | Gone? |
| On-Q-Ity | , | Closed 2013 |
| RCP Diagnostics | , | Acquired by Provista Life Sciences, Dec 2006 |
| Ingenium Therapeutics | Daejon, Korea | NK Cell Therapy |
| Denk Pharma | Munich, Germany | Generics |
| Allovate Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| SpectraScience | , | Shell company, Jul 2019, $482k market cap |
| Angiomics | , | Product being sold by another company |
| IFM Therapeutics (1) | , | Acquired by BMS after less than a year, $300M + $1B milestones. Spinning out some assets into new company with same name |
| Epione Laboratories | , | Website down Jul 2020 - Dec 2020 |
| Steba Biotech | , | Renamed ImPact Biotech |
| Kinetigen | , | Renamed Nuventra Pharma Sciences, Sep 2013 |
| Massive Genomics | , | Website down Feb 2022 - Jul 2022 |
| ProtAffin | , | Winding Down |
| GeneTrol | , | Merged with CytoPharm |
| Kanaph Therapeutics | Seoul, Korea | Bispecific Antibodies, Small Molecules, ADCs |
| EirGen Pharma | Waterford, Ireland | Contract Small Molecule Manufacturing & Development |
| Guided Therapeutics | Norcross, GA | Cervical Cancer Test |
| , | Website down Oct 2025 - Feb 2026 | |
| Cardiva Medical | , | Acquired by Haemonetics, Jan 2021, $510M |
| RetiPharma | , | Dissolved Nov 2019 |
| Pharmascience | Montréal, QC | Generics |
| Darwin Molecular | , | Acquired by Chiroscience, Nov 1996, $120M stock |
| Verily Life Sciences | Dallas, TX | Using technology to solve health problems |
 |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Summation Bio | , | Shut down May 2023 |
| Cadila Pharmaceuticals | Dholka, India | Contract Small Molecules |
| , | Now Nexus Spine | |
| Element | Eagan, MN | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Sano Genetics | Cambridge, UK | Genome Sequencing for Research Purposes |
| Hansa Biopharma | Lund, Sweden | Novel immunomodulatory enzymes for transplantation and acute autoimmune diseases |
| , | Renamed Fareon, Feb 2025 | |
| NeuralInk | Fremont, CA | Neural Implants |
| Nuwill Research & Innovations | Bengaluru, India | Formulation Development, Analytical Services |
| Valor Biotherapeutics | , | All employees gone as of Dec 2017 |
| Kura Oncology | San Diego, CA | Small Molecules |
| Inovio Pharmaceuticals | San Diego, CA | DNA Vaccines |
| Clinigen Group | Burton on Trent, UK | Clinical Manufacturing, Consulting, Generic Drugs |
| CellRight Technologies | , | Acquired by Tissue Regnix, Aug 2017 |
| OcuMedic | , | Website down Dec 2022 - Feb 2023 |
| Urotronic | , | Acquired by Laborie Medical Technologies, Oct 2023, up to $600M |
| Actokine | , | Not registered as a business in MA Dec 2018 - Feb 2022 |
| , | Acquired by Healx, Sep 2025 | |
| Advanced Electrophoresis Solutions | Cambridge, ON | Electrophoresis |
| NeoGenomics | Fort Myers, FL | Genetic & Diagnostic Testing |
| Applied Pharmaceutical Science | Beijing, China | Anti-tumor Drugs |
| Intrinsic Bioprobes | , | Acquired by Thermo Fisher Sep 2011 |
| Zyno Medical | , | Website down Mar 2024 - Sep 2024 |
| LaunchWorks CDMO | Beverly, MA | Contract Manufacturing |
| Biologics Process Development | , | Acquired by ViroPro, 2010 |
| Miltenyi Biotec | Auburn, CA | Magnetic Cell Sorting Products |
| ProBio | Pennington, NJ | Genomics, Proteomics, Biologics |
| Visirna Therapeutics | Shanghai, China | RNAi Therapeutics: siRNA Drugs |
| Reviticell | , | Website redirecting to a plea for investments, Oct 2015 |
| Tonbo Biosciences | , | Acquired by Cytek Biosciences, Nov 2021 |
| Impact Analytical | Midland, MI | Contract testing laboratory. comprehensive analytical services |
| Tarabios | , | Website down Feb 2025 - Jul 2025 |
| PuraMed Bioscience | , | Stock worthless, website gone Oct 2016 |
| Lipid Genomics | , | Seems unserious |
| Hettich | Tuttlingen, Germany | Centrifuges & Incubators |
| Cerebrotech | , | Website down Feb 2023 - Jul 2023 |
| CellGenEx | , | Merged with CDR Therapeutics to form Xcyte, Jan 1998 |
| , | Website down Aug 2025 - Jan 2026 | |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| IGM Biosciences | , | Acquired by Concentra, Aug 2025; Strategic Alternatives, ended both programs, Jan 2025 |
| JHL Biotech | , | Renamed Eden Biologics, Feb 2021 |
| DIAsource ImmunoAssays | Louvain-la-Neuve, Belgium | Clinical Diagnostic Products |
| Sterifre Medical | , | Website down Feb 2025 - Jun 2025 |
| Transgenomic | , | Merged into Precipio, Jun 2017 |
| GDMC | , | Website down Jul 2024 - Dec 2024 |
| Allendale Pharmaceuticals | , | Acquired by Synova Healthcare, Feb 2007, $16M stock |
| PGXIS | , | Spun out Adorial, but no mention that PGXIS was folded. No website or info. |
| DermaRite | North Bergen, NJ | Foam Dressing |
| Aves Labs | , | Now part of Antibodies Inc |
| OrPro Therapeutics | , | No business filings in CA, Nov 2016 - Jul 2024 |
| Pacific PharmaScience | , | Business filings late, Jan 2023 - Aug 2025 |
| Veloxity Labs | Peoria, IL | Bioanalytical CRO focused on LC-MS bioanalysis. |
| Vexim | , | Acquired by Stryker, Feb 2018, $216M |
| BioArctic | Stockholm, Sweden | CNS treatments |
| Pear Bio | London, UK | Cancer Treatment Selection |
| Biointron | Shanghai, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Boston Scientific | St. Paul, MN | Medical Devices |
| NodThera | Little Chesterford, UK | NLRP3 inflammasome inhibitors |
| Axogen | Alachua, FL | Nerve Tissue Processing |
| Axoft | Cambridge, MA | Implantable Neuro Probes |
| Axplora | Vizag, India | API manufacturing, kilo lab |
| Syngene International | Bangalore, India | Contract Research |
| Evergreen Therapeutics | Bethesda, MD | AI Pharmaceutical Company |
| Sartorius Stedim Biotech | Goettingen, Germany | Lab products, Equipment, Consumables |
| Affini-T Therapeutics | Watertown, MA | TCR Cell Therapy |
| Neurosolutions | Coventry, UK | Translational Preclinical Neuroscience Research Services |
| Carbiotix | Palo Alto, CA | Gut Microbiota Testing |
| Tieos Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| Quantori | Cambridge, MA | Digital transformation, data science, AI, and cloud solutions |
| Keli Therapeutics | Kaunas, Lithuania | Regenerative Cellular Therapy |
| Hansa Medical | , | Renamed Hansa Biopharma |
| Xanodyne | , | Reported closed prior to Oct 2013 |
| MilliporeSigma | Madison, WI | Small Molecules |
| Univercells Technologies | Nivelles, Belgium | Bioreactors, Upstream Equipment |
| Alper Biotechnology | , | Gone |
| AOP Orphan Diseases | Sofia, Bulgaria | Orphan disease treatments |
| Glysantis | , | Shut down Late 2020 |
| Sirenas Marine Discovery | , | Business not registered since 2015 as of Sep 2019 |
| Via Biomedical | , | Acquired by Heraeus Medical, Sep 2019 |
| Recipharm | Masate, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Lonza | Verviers, Belgium | Small Molecules, Biologics |
| Rentschler Biotechnologie | , | Renamed Rentschler Biopharma |
| 206 Ortho | , | Shut down 2021 |
| Northern Nanopore Instruments | , | Acquired by Oxford Nanopore, Nov 2023 |
| Applied Molecular Transport | , | Merged with Cyclo Therapeutics, Sep 2023 |
| Fosun Pharma | Sydney, Australia | Small molecules, diagnostics, traditional |
| Precidiag | , | Renamed Piton Therapeutics, Jan 2023 |
| Accurate Clinical Research | Richmond, TX | Clinical Research |
| , | Website taken over Nov 2025 - Mar 2026 | |
| InnaVirVax | , | Renamed Minka Therapeutics, 2018 |
| Khepri Pharmaceuticals | , | Acquired by Arris Pharmaceuticals Nov 1995 |
| Forendo Pharma | , | Acquired by Organon, Dec 2021, $954M |
| August Bioservices | Nashville, TN | Research & Development Services |
| Oligasis | , | Changed named to Kodiak Sciences |
| Stuart Pharmaceuticals | , | Acquired by Atlas Chemical Industries |
| Amgen | Dún Laoghaire, Ireland | Small Molecules, Biologics |
| Aytu BioScience | , | now Aytu BioPharma |
| Precision Medical Technologies | Warsaw, IN | End-to-end implant (this location) and instrument manufacturing |
| Bivision Pharmaceuticals | Shanghai, China | Radiopharmaceuticals |
| Recordati | Saint-Victor, France | Small Molecule Manufacturing |
| BioLife Cell Bank | , | Renamed AveXis, Jan 2014 |
| Intersect ENT | , | Acquired by Medtronic, May 2022, $1.1B |
| Vasomune Therapeutics | Toronto, ON | Therapeutics to combat vascular dysfunction to stabilize the body as it battles disease |
| Vyant Bio | , | Liquidated, Nov 2023 |
| Charles River Laboratories | Charleston, SC | Research Animal Models and Preclinical Research |
| RuiYi | , | Renamed Bird Rock Bio, Dec 2015 |
| Pfizer | Puurs, Belgium | Packaging |
| GenDx | Utrecht, Netherlands | HLA Typing via NGS |
| APP Pharma | , | Bought by Fresenius Kabi, Jul 2008, $4.6B |
| Cunde Medical | , | mRNA Cell Therapy combo |
| Dermik Laboratories | , | Owned by Sanofi, Acquired by Valeant Jul 2011 |
| Saffron Pharma | Faisalabad, Pakistan | Small molecule Drugs: Tablets, Capsules etc. |
| Cortechs.ai | San Diego, CA | Imaging technology |
| Mankind Pharma | New Delhi, India | OTC? |
| EdiGENE | , | Renamed Modalis Therapeutics, Sep 2019 |
| DermaSensor | Miami, FL | Skin Cancer Diagnosis Device |
| Cadista Pharmaceuticals | , | Now Jubilant Cadista Pharmaceuticals |
| Domain Surgical | , | Merged with OmniGuide Surgical, 2016 |
| , | Website down Oct 2025 - Feb 2026 | |
| CTD Inc. | , | Renamed Cyclo Therapeutics |
| Engage Therapeutics | , | Acquired by UCB, Jun 2020, $125M |
| Nexus-Dx | San Diego, CA | POC Diagnostics |
| Neuronyx | , | Became Garnet BioTherapeutics, Mar 2009 |
| Polytherapeutics | , | Gone Jun 2018 |
| Aclaris Therapeutics | Wayne, PA | Novel topical dermatological therapies |
| Canary Medical | Carlsbad, CA | Implant Data Transmission |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Paramita Therapeutics | , | Website down Sep 2024 - Mar 2025 |
| Rentschler Fill Solutions | , | Website gone Jun 2020 |
| Biologos | Glendale Heights, IL | Standard and custom cell culture media and reagents |
| NKT Therapeutics | , | Shut down May 2021 |
| Adimab | Lebanon, NH | Yeast-Derived Antibodies |
| Indalo Therapeutics | , | Website redirecting to a stay-at-home mom page |
| TwoStep Therapeutics | San Carlos, CA | PIP Therapies |
 |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| IVAX Corporation | , | Acquired by Teva 2006 |
| Iaso Therapeutics | East Lansing, MI | Vaccines |
| Charles River Laboratories | Sherbrooke, QC | Research Animal Models and Preclinical Research |
| Great Basin Corp | , | Website down, Mar-Apr 2018 |
| Cell Sciences | Newburyport, MA | Lab Reagents, Antibodies |
| OXOS Medical | Atlanta, GA | X-ray Technology |
| Apex Medical Technologies | , | Website from 2010 as of Feb 2025, emails bouncing |
| Coastal Genomics | , | Acquired by Yourgene, Aug 2020, up to $5.5M + $8M milestones |
| Transcend Therapeutics | New York, NY | Psychedelics |
| Embark Biotech | , | Acquired by Novo Nordisk, Aug 2023, €15M |
| Peak Bio | , | Merged with Akari Therapeutics, Nov 2024 |
| AutoGenomics | , | Renamed, SOLVD Health Dec 2020; Acquired by Prescient Medicine Holdings Apr 2019 |
| , | Shut down Nov 2025, Tempus acquired assets | |
| PolyNeuroS | , | Website down May 2022 -Sep 2022 |
| Vtesse | , | Acquired by Sucampo Pharmaceuticals, Apr 2017, $200M; Spunout of Cyden Orphan drug accelerator |
| HiberCell | Roseville, MN | Tumor dormancy detection and treatments |
| BioNTech | Cambridge, MA | mRNA, Vaccines, Biologics |
| |
Cambridge, MA | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Anika Therapeutics | Bedford, MA | Small Molecules |
| Regend | Shanghai, China | Cell Therapy, Manufacturing |
| Neurologix | , | Bankrupt, Liquidation |
| Spruce Biosciences | South SF, CA | Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis |
| Transition Therapeutics | , | Bought by Opko, $60M stock, Jul 2016 |
| Amorsus | , | Website Gone 8-30-13 |
| Surgical Specialties | , | Renamed Corza Medical after acquisition/merger |
| Synereca Pharmaceuticals | , | Website gone May 2018 |
| Rubius Therapeutics | , | Shutting down Feb 2023; Axed existing programs to create new ones Sep 2022 |
| Altimmune | Gaithersburg, MD | Biologics, Vaccines, Drug Delivery |
| SciGenom | Cochin, India | Next-gen sequencing services, bioinformatics |
| Ventaleon | , | Shut down 2020 |
| MicroGEM | , | Bankrupt, assets acquired by MicroGEM Apr 2016 |
| Abcalis | Braunschweig, Germany | Recombinant Antibodies |
| Acanthas Pharma | Dundas, ON | Small Molecule CDMO |
| Pharsight | , | Merged with Tripos to become Certara |
| Fresenius Kabi | Labesfal, Portugal | Contract Manufacturing |
| MMS Holdings | Canton, MI | Clinical Research Organization |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Patronus Biotech | Singapore, | |
| Dendritic Nanotechnologies | , | Acquired by starpharma, Oct 2006 |
| Analogic | Peabody, MA | Medical Imaging |
| Cajal Therapeutics | Seattle, WA | Neurodegenerative Therapies |
| PellePharm | , | Website down Sep 2023 - Mar 2024; Sold only product to Sol-Gel, Jan 2023 |
| Azelead | , | Website down Feb 2023 - Jul 2023 |
| SpectronRx | Indianapolis, IN | Diagnostics, Radionucleotides, Contract Manufacturing |
| Greenstone Biosciences | Palo Alto, CA | |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Fountain Medical Development | , | Renamed ClinChoice, Sep 2020 |
| Ceros Pharmaceuticals | , | Acquired by Auxeris Therapeutics, Jan 2004 |
| Immunservice | Hamburg, Germany | Cell Culture Reagents, Proteins |
| NeuroVasx | , | No website May 2019, founded 1997 |
| Medelis | Ypres, Belgium | Clinical Research |
| Zurich Medical | Minneapolis, MN | Cardiovascular Devices |
| Devicor Medical Products | Cincinnati, OH | Breast Cancer Diagnosis |
| Globe Life Sciences | London, UK | Strategy Consulting |
| Acucela | , | folded into Kubota Vision |
| Porton Advanced Solutions | Suzhou, China | Cell & Gene Therapy CDMO |
| Immunologix Laboratories | Tampa, FL | Lab Services |
| STAT3 Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Alpioner Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| Aoxing Pharmaceutical | , | Merged with Cyclo Therapeutics, Sep 2023 |
| NeoVentures | London, ON | Custom Aptamers |
| Imeka | Sherbrooke, QC | Neuroimaging |
| , | Acquired by StarFish Medical, Nov 2024 | |
| Corthera | , | Acquired by Novartis 2010, $120M + $500M milestones |
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Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Attyloid | Düsseldorf, Germany | Quantitative detection of single oligomers and aggregates |
| Compendia Bioscience | , | Acquired by Life Technologies, Oct 2012 |
| Vigeo Therapeutics | Cambridge, MA | Biologics for Cancer |
| Pharmatek | , | Acquired by Catalent, Sep 2016 |
| Aulos Bioscience | Larkspur, CA | IL-2 binding monoclonal antibodies |
| Ayerst Labs | , | Merged with Wyeth 1943 |
| CONMED | Greenwood Village, CO | Surgical, Medical Devices |
| Open Monoclonal Technology | , | Acquired by Ligand, Jan 2016, $178M |
| Profil | Neuss, Germany | Clinical Research Services |
| Nerviano Medical Sciences | Nerviano, Italy | Oncology drugs |
| Vie Diagnostics | , | Renamed Phoresa |
| Genovac | Fargo, ND | Antibody Discovery Tools |
| Humanwell Pharmaceutical | Ballwin, MO | Anesthetic and pain medications |
| S-Cubed | Wantage, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Orros Therapeutics | , | gone 2018 |
| PharmaMatrix | Wilson, NC | Pharma Automation Consulting |
| Stelexis Therapeutics | New York, NY | Drugs targeting pre-cancerous stem cells |
| Stage Cell Therapeutics | , | Bought by Juno Therapeutics, May 2015, €52.5 million |
| Promaxo | Oakland, CA | Small form MRI |
| Interferon Source | , | Bought by PBL Assay Science |
| Juno Therapeutics | , | Acquired by Celgene, Jan 2018, $9B |
| Rasa Life Science Informatics | Pune, India | Bioinformatics |
| GeneVivo | , | Unknown Fate |
| OSI Pharmaceuticals | , | Bought by Astellas |
| Axplora | Le Mans, France | HPAPIs, ADC conjugation / payload |
| Synapse Biomedical | Oberlin, OH | Diaphragm Pacing System |
| Pharmacopeia | , | Acquired by Ligand Pharmaceuticals 2008 |
| Biodel | , | Merged with Albireo, Oct 2016 |
| Avalon Pharmaceuticals | , | Bought by Clinical Data |
| Artimplant | , | Bankrupt, 2013 |
| Vernal Biosciences | Colchester, VT | mRNA Production |
| , | Merged with ATAI Life Sciences, Nov 2025, became AtaiBeckley; fka Beckley Psychadelics | |
| Gentel Bio | , | Ceased Operations 2012 |
| Oncolinx | , | Website down Oct 2021 - Mar 2022 |
| Platomics | Vienna, Austria | Automated Regulatory Platform |
| Artivila Therapeutics | Shenzhen, China | AI Drug Discovery |
| Silverback Therapeutics | , | Merged with ARS Pharmaceuticals, Nov 2022 |
| Bionix Implants | , | Bought by CONMED, Mar 2003 |
| Synovex | , | Renamed Adheron Therapeutics |
| Odonate Therapeutics | , | Shut down Mar 2021 |
| Azenta Life Sciences | La Jolla, CA | Automation Products |
| Bioverativ | , | Acquired by Sanofi, Jan 2018, $11.6B; Biogen's spinout hemophilia group |
| Ailex Pharmaceuticals | , | Doesn't seem active, Jun 2025; aka RD2RX |
| Aurigon | , | Website down Oct 2021 - Mar 2022 |
| iTeos Therapeutics | , | Winding down May 2025, shell acquired by Concentra, Jul 2025 |
| MaSTherCell | , | Acquired by Catalent, Feb 2020; Bought by Orgenesis, Mar 2015, $24M in shares |
| DiObex | , | Shut Down 2009 |
| Biocare Medical | Pacheco, CA | Immuno histochemistry machines & reagents |
| , | Renamed Damora Therapeutics, Mar 2026 | |
| Autonomic Technologies | , | IP acquired by Unity HA |
| Lantheus Medical Imaging | Bedford, MA | Small Molecules for Imaging |
| Weavr Health | , | Website down Dec 2022 - Apr 2023; fka Boston Microfluidics |
| Noscendo | Duisburg, Germany | Pathogen ID via NGS |
| CIMYM BioSciences | , | Defunct Joint Venture, sold assets 2012 |
| Triage Wireless | , | Now named Sotera Wireless |
| Synosia Therapeutics | , | Acquired by Biotie |
| Ribon Therapeutics | , | Shut down May 2024 |
| Siloam Biosciences | , | Acquired by MiCo BioMed, May 2018 |
| IntelliPharmaCeutics | , | Website down Feb 2024 - Jul 2024 |
| UGA Biopharma | Hennigsdorf, Germany | Cell Product, Cell Development, Process Development, Analytical |
| Stemnion | , | Renamed Noveome Biotherapeutics, Jan 2009 |
| Thievon-Wright Consulting Group | , | Acquired by ERG Clinical, Apr 2018 |
| , | Website down Dec 2025 - Mar 2026; Formed out of Merger between Transcriptic & 3Scan | |
| Frontage | Hayward, CA | Contract Research & Development, Clinical Services, CMC Services |
| Genocury Biotech | Shenzhen, China | Off-the-shelf Cell & Gene Therapy |
| BeOne Medicines | Suzhou, China | Small Molecules, Monoclonal Antibodies |
| m2p-labs | , | Acquired by Beckman-Coulter, Nov 2020 |
| Cobra Introducer | , | Everyone gone Aug 2022 |
| Riboxx Pharmaceuticals | , | Sole employee is professor, no news since 2017 as of Apr 2021 |
| , | Website down Jan 2026 - May 2026 | |
| InfiCure Bio | , | Website down Apr 2024 - Aug 2024 |
| Algorx Pharmaceuticals | , | Acquired by Corgentech in reverse merger, Dec 2005 |
| Partner Therapeutics | Lexington, MA | Biologics |
| Xenomics | , | Now TrovaGene |
| Avista Pharma Solutions | , | Bought by Cambrex, Jan 2019, $252M; Formed from the CMC business of Array BioPharma and contract services business of Scynexis |
| , | Merged with Cohance, May 2025 | |
| cCAM Biotherapeutics | , | Acquired by Merck, Aug 2015, $605M |
| Visterra | , | Acquired by Otsuka, Sep 2018, $430M |
| HMNC Brain Health | Munich, Germany | Psychiatric Treatments |
| Paradigm Shift Therapeutics | , | Shut down Apr 2020 |
| Camurus | Lund, Sweden | Specialty medicines |
| Peptide Logic | , | Website down Jun 2024 - Nov 2024 |
| Otic Pharma | , | Merged with Tokai Pharmaceuticals, May 2017 |
| Evoke Medical | , | Renamed DirectSync Surgical |
| Kayem Pharmaceutical | , | Renamed Jonakayem Pharma - Formulation |
| Orbus Pharma | , | Website Gone |
| Ayala Pharmaceuticals | , | Products acquired by OS therapies, Apr 2025; Major products acquired by Immunome, 2024; Merged with Biosight, Oct 2023; Merged with Advaxis, Jan 2023 |
| PRACS Institute | , | Bankrupt 2013 |
| Boehringer Ingelheim | Ingelheim am Rhein, Germany | Small Molecules, Biologics |
| BioSkyrb Genomics | Durham, NC | Amplification Technology for Improved Genomic Sequencing |
| Acertara Acoustic Laboratories | Tokyo, Japan | Ultrasound probe testing devices |
| Exiris | Rome, Italy | Human Therapeutic Antibodies |
| Photonamic | , | Website down Apr 2019 - Aug 2019 |
| Nobel Biocare | Kloten, Switzerland | Implants, Biologics |
| Codon Devices | , | Closed Apr 2009 |
| Reichert | Depew, NY | Eye diagnostic instruments and equipment |
| Biomerix | , | Website gone Jun 2016, CEO only employee on LI |
| Gritstone Oncology | , | Renamed Gritstone Bio, May 2021 |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| Exogene | Oxford, UK | AI to find TCRs for cancer therapy |
| Genedata | Basel, Switzerland | Bioinformatics |
| Pharma Consulting Associates | , | Website taken over Mar 2025 - May 2025 |
| MingMed Biotechnology | Guangzhou, China | Small Molecules, Immunotherapy, Botox |
| HeavyBio | Shenzhen, China | Antibodies, Antigens |
| BlueArc Biosciences | Del Mar, CA | Diagnostics (Biosensors with Synthetic Biology |
| Blueshift Biotechnologies | , | Acquired by MDS Analytical, Jun 2008, $13M |
| Nanoform | Helsinki, Finland | Nanoparticles to Assist Drug Delivery |
| LifeLens Technologies | Ivyland, PA | Physiologic Monitoring |
| Checkmate Pharmaceuticals | , | Acquired by Regeneron, May 2022, $250M |
| Vivasc Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Rhombus Pharma | Gandhinagar, India | Generics |
| Evestra | San Antonio, TX | Women's Health |
| CytoSorbents | Princeton, NJ | Blood Purification Therapy |
| AMRI | , | Renamed Curia, Jul 2021 |
| Blue Cross Laboratories | Mumbai, India | Generics |
| Paradigm Biopharmaceuticals | Melbourne, Australia | Drug Repurposing |
| Lygos | Hayward, CA | Biologically-derived specialty chemicals |
| Fortis Life Sciences | Boston, MA | Reagents, antibodies, enzymes and lateral flow assay components, plus CDMO, contract R&D services |
| Vanquish Oncology | , | No news 2015-2021 |
| Predict4Health | , | Renamed Okeiro, May 2025 |
| , | Shut down late 2025 | |
| Symmune Therapeutics | , | Website gone Dec 2019 - Aug 2020 |
| Horizon Surgical Systems | Malibu, CA | Robotic Cataract Surgical Devices |
| MayTrex Therapeutics | , | Website down Aug 2023 - Apr 2024 |
| Opna Bio | Epalinges, Switzerland | Novel oncology therapeutics |
| , | Website down Jan 2026 - May 2026 | |
| O'Hara Technologies | Richmond Hill, ON | Solid Dosage Pharma Equipment |
| AngioDynamics | Hong Kong, China | Array of Medical Devices |
| Asalyxa Bio | , | Website down Feb 2023 - Jul 2023 |
| Woodland Biosciences | , | Acquired by Ichor Life Sciences, Sep 2021 |
| NEC Oncoimmunity | , | Renamed NEC |
| Psyadon Pharmaceuticals | , | Acquired by Emalex Biosciences, Aug 2018 |
| Arbor Pharmaceuticals | , | Acquired by Azurity, Sep 2021 |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Titan Medical | , | Renamed Conavi Medical, Oct 2024 |
| Canfield Scientific | Parsippany, NJ | Medical Imaging, Clinical Research Services |
| Accord Healthcare | Ahmedabad , India | Generics |
| Bionoxx | Yangsan, Korea | Tumor-targeting Antigen |
| Alcon | Schaffhausen, Switzerland | Eye-Care Products |
| Cellon | , | Website down Jun 2023 - Dec 2023 |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| EzBiome | Gaithersburg, MD | Microbiology Services |
| ReadCoor | , | Acquired by 10X Genomics, Oct 2020 |
| Panther Biotechnology | , | Acquired in Reverse Merger by media company, presumably for ticker symbol |
| Thrive Bioscience | Beverly, MA | Analytical & automation technology |
| Levitronix Technologies | Framingham, MA | Pumps and Related Products |
| Biosidus | Buenos Aires, Argentina | Biosimilars |
| Cylene Pharmaceuticals | , | Website gone 12-21-13, CEO switched jobs Oct 2013 |
| Automated Medical Instruments | , | Renamed AblaCor, Jan 2013 |
| Scientific Industries | Bohemia, NY | Lab equipment |
| CerRx | , | Website down Feb 2021 - May 2021; Company seems inactive, but trial updated on clinicaltrials.gov in 2019 |
| Synoesis Therapeutics | , | No website Jan 2020 - Aug 2021; 2018 or earlier startup |
| Entellus Medical | , | Acquired by Stryker, Feb 2018, $662M |
| Otsuka | Rockville, MD | Small Molecules |
| Enzo Life Sciences | Farmingdale, NY | Life Sciences R&D Products |
| Aciont | , | Website down Jun 2023 - Dec 2023 |
| Vertex | Cambridge, MA | Small Molecules, Gene Editing, Cell Therapy |
| Star Scientific | , | Renamed Rock Creek Pharmaceuticals Jun 2014 |
| Sequel Med Tech | Manchester, NH | Insulin Delivery |
| Kemp Proteins | Frederick, MD | Mammalian & insect culture services |
| BioMarin Pharmaceutical | San Rafael, CA | Biologics |
| Adrenergics | , | Gone Sep 2017 |
| HartmannWillner | , | Website down Feb 2025 - Jul 2025 |
| ExcellGene | Monthey, Switzerland | Cell line development & engineering. Protein engineering. GMP-process development (USP&DSP). |
| Brolex | , | Exclusively licensed product to Cooper Surgical |
| Ascensia Diabetes Care | Parsippany, NJ | Diabetes Devices |
| Celloram | Cleveland, OH | Cell therapy and small molecules |
| iota Biosciences | Alameda, CA | Implantable Bioelectronic Devices |
| Mist Pharmaceuticals | , | Website gone, no info Nov 2019 |
| Psomagen | Rockville, MD | Genetic Sequencing |
| C4 Therapeutics | Watertown, MA | Ubiquitin-proteasome system based therapeutics, protein degradation |
| Attentive Therapeutics | , | 10 years old, only CEO on LI who has always had diff job |
| Hydrocapsule | , | Website gone Oct 2022 - Feb 2023 |
| GenoSpace | Boston, MA | Platform for genomic data |
| SK Life Science | Paramus, NJ | Small Molecules for CNS |
| Cytiva | Freiburg, Germany | Medical Devices |
| Sharp | Rhymney, UK | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| , | Website down Jul 2025 - Dec 2025 | |
| Orochem | Naperville, IL | Reagents, Automation |
| Halsa Pharmaceuticals | , | Award in 2008, No additional info, presume defunct |
| Morvus Technology | , | Website being update Dec 2024 - Aug 2025; Website down Jun 2024 - Aug 2024 |
| Bioinduction | , | Acquired by Amber Tx, Sep 2023 |
| avateramedical | Jena, Germany | Robot-assisted, Minimally-invasive Surgery |
| Pie Medical Imaging | Maastricht , Netherlands | Cardiac Imaging |
| Somerset Pharma | Somerset, NJ | Sterile injectable and ophthalmic drugs |
| Chi-Med | , | Renamed Hutchmed, Mar 2021 |
| Zelos Pharmaceuticals | , | Renamed Azelon Pharmaceuticals |
| Enochian Biosciences | , | Renamed Renovaro Biosciences, Aug 2023 |
| , | CA filings late Jun 2024 - Oct 2025 | |
| Hepregen | , | Joined with ESI Bio to become Ascendance Biotechnology, Nov 2015 |
| Drugabilis | Villejust, France | Druggability Services |
| ReSolution Latin America | Buenos Aires, Argentina | Clinical Research Consulting |
| Grunenthal | Origgio, Italy | Small molecules |
| PrimeVax Immuno-Oncology | Orange, CA | Dengue Virus combined with autologous dendritic cells |
| Asterand Bioscience | , | Bought by BioreclamationIVT, Aug 2017; Bought by Stemgent, Aug 2012 |
| , | Renamed Ensera, Oct 2025 | |
| Oxford Biomedica | Oxford, UK | Gene-based Medicines |
| BAP Pharma | Marlow, UK | Clinical Supplies |
| Dornier MedTech | Singapore, Singapore | Urology Devices |
| insitro | South SF, CA | Machine Learning, Drug Discovery |
| Celixir | , | Shell acquired Dec 2023 |
| Linkage Biosciences | , | Acquired by Thermo Fisher, Jul 2017 |
| Velentium Medical | Richmond, TX | Design and manufacturing of therapeutic and diagnostic active medical devices |
| Zimmer Biomet | Warsaw, IN | Medical Implants |
| Genedrive | Manchester, UK | Molecular Diagnostics Platform |
| Modis Therapeutics | , | Bought by Zogenix, Sep 2019, $250M + $150M milestones |
| Ozgene | Bentley, Australia | Genetically modified mice |
| BugSeq | Vancouver, BC | Sequencing Analysis |
| Affomix | , | Acquired by Illumina, Jul 2010 |
| Norgen Biotek | Thorold, ON | Products for sample collection, sample preparation and sample detection. Comprehensive research services |
| Ceramedix | , | No website Dec 2019 - Aug 2021; Hiring for a job Jan 2021; LinkedIn points to inactive website Aug 2021 - Jul 2024 |
| Emphasys Medical | , | Assets acquired by Pulmonx, May 2009 |
| Titan Clinical Solutions | , | Website down Apr 2022 - Aug 2022 |
| Injex Pharma | , | Bought by Chinese Investor, Jan 2016 |
| Dornier MedTech | Sillingy, France | Urology Devices |
| SegAna | , | Website down May 2021 - Sep 2021 |
| Aizant | Hyderabad, India | Drug, API R&D and Manufacturing |
| AI Proteins | Boston, MA | Synthetically-designed Proteins |
| Volta Medical | Marseille, France | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| Johnson & Johnson MedTech | Somerville, NJ | Medical Devices |
| Shockwave Medical | Santa Clara, CA | Lithoplasty for treating occlusive calcified lesions |
| AlivaMab Discovery Services | , | Renamed AlivaMab Biologics, Oct 2023 |
| Baxter | Deerfield, IL | Medication Delivery |
| Calypte Biomedical | , | Gone |
| Endomag | Cambridge, UK | Biopsy Tracer |
| Piramal | Ahmedabad, India | CDMO |
| Velocity Pharmaceutical Development | , | Now part of X-37 |
| CROSSJECT | Dijon, France | Needle-free Injection |
| VastBiome | , | Renamed PragmaBiome |
| Bliss Biopharmaceutical | Hangzhou, China | Antibody-Drug Conjugates |
| Pharmexon | Prague, Czech Republic | Consulting |
| Nemera | Le Tréport, France | Drug Delivery Systems |
| CellforCure | , | Acquired by Novartis, Feb 2019 |
| Flex Medical | Austin, TX | Personal diagnostics, advanced surgical tools |
| Almac | Craigavon, UK | Pharmaceutical Services |
| Cardionomic | , | Website down Jul 2024 - Dec 2024 |
| Cartography Biosciences | South SF, CA | Cancer Immunotherapies |
| Xenova | , | Acquired by Celtic Pharma |
| DRP Biomedical | , | Renamed HemaFlo Therapeutics, Jan 2016 |
| Corticrine | , | Bought by Actinogen, Aug 2014, $5.75M |
| Envoy Therapeutics | , | Acquired by Takeda, Nov 2012 |
| Mobius Medical | Sydney, Australia | Clinical Research |
| Lux Biosciences | , | Gone |
| Apofore | , | Shut down, Dec 2015 |
| Therox Pharmaceuticals | , | Acquired by OXIS International, Jul 1995 |
| Synergy Pharmaceuticals | , | Acquired by Bausch Mar 2019; Bankrupt, Dec 2018, want to accept Bausch bid $200M for assets, auction forthcoming |
| StratifAI | Berlin, Germany | Platform linking histology, RNASeq, and patient outcomes |
| Chondrial Therapeutics | , | Merged with Zafgen, May 2020, became Larimar Therapeutics |
 |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Genovis | Cambridge, MA | Nanoparticles |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| Orphidia | , | No business filings 2017-2020; Website down Oct 2020 - Jan 2021 |
| Getinge | Fairfield , NJ | Medical Technology |
| Foguera | , | Bought by Sandoz Jul 2012, $1.525B |
| Uncover Therapeutics | , | |
| Altasciences | Scott Township, PA | Contract Research |
| Novatim Immune Therapeutics | Shanghai, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Xinvento | , | Acquired by Rhythm Pharmaceuticals, Feb 2023, $5M + $206M milestones |
| BioTechnique | York, PA | Contract Pharmaceutical Manufacturing |
| Mapp Biopharmaceutical | San Diego, CA | Infectious Disease Treatment |
| Biopharm Services | Buckinghamshire, UK | Biotech Software |
| sb-Peptide | Saint Egrève, France | Custom peptide synthesis |
| Ancora Heart | Santa Clara, CA | Cardiac procedures for Mitral Valve Regurgitation |
| Hi-Tech Pharmacal | , | Acquired by Akorn, Apr 2014 |
| Syntax for Science | , | Acquired by Optimapharm, Nov 2020 |
| Octane Biotech | Lucknow, India | Generics |
| Transferra Nanosciences | , | Acquired by Evonik Jun 2016; fka Northern lipids |
| Ultragenyx Pharmaceutical | Woburn, MA | Small Molecules, Biologics |
| Pear Tree Pharmaceuticals | , | Merging into Dare Bioscience, May 2018 |
| Cartherics | Notting Hill, Australia | Cell Therapy Technology |
| Saghmos Therapeutics | , | |
| Athena Diagnostics | , | Acquired by Fisher Diagnostics, Mar 2006 |
| Recipharm | Paderno Dugnano, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Shut down Dec 2025 | |
| Mirador Therapeutics | San Diego, CA | Drugs for inflammatory and fibrotic diseases |
| Evozyne | Chicago, IL | Protein Design Platform |
| PolyNovo | Port Melbourne, Australia | Biodegradable material |
| TumorGen | San Diego, CA | Cancer Treatments |
| Surface Bioadvances | , | Website Gone, Aug 2016; SBIR grant |
| Indian Immunologicals | Hyderabad, India | Veterinary Biologics, Vaccines |
| Juvise Pharmaceuticals | Paris, France | Small Molecule |
| Pattern Bioscience | Austin, TX | Rapid Diagnosis for Antibiotic Treatment |
| North Coast Biologics | , | Website down Mar 2023 - Apr 2023 |
| Imagene AI | Miami, FL | Image-based Biomarker Detection |
| Kelliop | Newark, CA | Diagnostic Reader |
| H2Biologics | , | Website down Aug 2024 - Feb 2025 |
| ZS Pharma | , | Bought by AstraZeneca Nov 2015, $2.7B |
| RecomGenex | , | Renamed TargetEx Biosciences |
 |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Cellistic | Mont-Saint-Guibert, Belgium | Cell Therapy Platforms |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Tongjitang Chinese Medicines Company | , | Bought by Winteam Pharmaceutical |
| Validogen | Raaba-Grambach, Austria | Contract protein expression, strain development, cell banking |
| AdvanDx | , | Acquired by OpGen, Jul 2015 |
| , | Website down Dec 2025 - Apr 2026 | |
| Biosyngen | Singapore, Singapore | Cell & Gene Therapy, Antibodies |
| Pathwork Diagnostics | , | Closed 2013 |
| Algok Bio | Bellevue, WA | Small Molecules, Monoclonal Antibody |
| Colibri Heart Valve | Louisville, CO | Heart Valve |
| Famar | Anthoussa, Greece | Contract Manufacturing - Small Molecules |
| Greenleaf Health | , | Acquired by Validant, Apr 2021, now part of Eliquent Life Sciences |
| CRI | , | Now BiomericsATL |
| CIMA Labs | , | Acquired by Teva, May 2011 |
| Gene Sciences | , | Shut Down Jul 2019 |
| HaiHe Biopharma | Shanghai, China | Small Molecules |
| Capo Therapeutics | , | Not registered as business in CA Mar 2020, no news since 2017, no one on LinkedIn |
| EpimAb Biotherapeutics | Shanghai, China | Bi-specific Antibodies |
| 3F Therapeutics | , | Acquired by ATS Medical, Jan 2006 |
| Enthought | Austin, TX | Custom scientific software, AI/ML-driven data tools, and digital transformation services |
| QurAlis | Cambridge, MA | ALS cure - Small Molecules, ASO |
| NGX Bio | , | Website down May 2022 - Oct 2022 |
| Proteomedix | , | Acquired by Blue Water Biotech, Dec 2023 |
| Geneseeq Technology | Toronto, ON | Cancer Genomic Profiling |
| Allecure | , | Merged with MiniMed and CTL Immunotherapies to become MannKind, 2001 |
| Neocis | Miami, FL | Dental Surgery Robots |
| AdvaStim | , | Shut down, Dec 2017 |
| Theragenesis | Oppenheim, Germany | Medical Device Regulatory Consulting |
| AlmataBio | , | Acquired by Avalo Therapeutics, Mar 2024, $22M |
| Celtaxsys | , | No longer active, Aug 2020 |
| Zogenix | , | Acquired by UCB, Mar 2022, $1.9B |
| Fluxion Biosciences | , | Acquired by Cell Microsystems, Aug 2023 |
| RNA Therapeutics | , | No website Mar 2020 |
| Ariel Pharmaceuticals | , | Website redirecting to Takeda; Site Gone Sep 2013 |
| INCOG BioPharma | Fishers, IN | Injectable CDMO |
| Alkan Pharma | , | Acquired by Hikma, Apr 2011, $60.5M |
| Axplora | Gropello, Italy | API manufacturing, kilo lab |
| NovaCina | , | Merged with Biocina, Jan 2025 |
| Symbio | Port Jefferson, NY | Full-service CRO & Clinical Research Consulting in Dermatology, Ophthalmology and Women's Health. |
| Applied Proteomics | , | Assets bought by DiscernDx, Feb 2018, $1.85M |
| TP Therapeutics | , | Renamed Turning Point Therapeutics, Nov 2018 |
| Reach Separations | Nottingham, UK | Purification Services |
| Diavacs | , | Website gone Oct 2019 - Dec 2020 |
| |
Sofia, Bulgaria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Teleflex Medical | Mascot, Australia | Surgical and Medical Devices |
| Apollo Biopharmaceutics | , | Acquired by MitoKor, May 2001 |
| Access Cardiosystems | , | Went out of business after recalling all its products, Nov 2004 |
| Breathe BioMedical | Moncton, NB | Breath Diagnostics |
| , | Website down Aug 2025 - Jan 2026 | |
| Pfizer | Karachi, Pakistan | Small Molecules, Biologics, Vaccines |
 |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| PepLib Biotech | ZhuZhou, China | Peptides |
| Kedalion Therapeutics | , | Acquired by Novartis, Jun 2022 |
| GoodStart Genetics | , | Acquired by Invitae, Aug 2017 |
| Aspira Scientific | , | Gone Nov 2015 |
| BioWhittaker | , | Merged into Cambrex Oct 1997 |
| Biopta | , | Acquired by ReproCELL, combined with Reinnervate to become ReproCELL Europe, Jul 2016 |
| Macusight | , | Effectively acquired by Santen, 2008 |
| AgilVax | , | Website gone, CEO gone Oct 2021 |
| Klocke Group | Weingarten, Germany | Contract Manufacturing |
| Anazen Diagnostics | , | Part of Cardiox |
| Bioprofarma Bago | Caba, Argentina | Branded Generics |
| KOTAI Biotechnologies | Osaka, Japan | Immune AI platform and data analysis |
| Affinity Biologicals | Ancaster, ON | Proteins, Antibodies, Reagents |
| OncBioMune Pharmaceuticals | , | Shut down Jul 2021 |
| DNA Therapeutics | , | Acquired by Onxeo, Mar 2016, €1.7M |
| Ad-Tech Medical Instrument | Oak Creek , WI | Innovative electrodes for the surgical treatment of intractable epilepsy as well as devices for neurodiagnostic and neurosurgery |
| CytoCore | , | Gone; fka Molecular Diagnostics, Inc. |
| Oncolytics Biotech | San Diego, CA | Human Reovirus Delivery |
| Hemera Biosciences | , | Website down Nov 2024 - May 2025; Rights to only product (HMR59) acquired by Janssen, Dec 2020 |
| VedaLab | Cerisé, France | IVD rapid tests |
| Nycomed | , | Acquired by Takeda 2011 |
| Gerinda Therapeutics | , | Gone 2009 |
| Utah Medical | Midvale, UT | Devices focusing on women's health |
| GlycoRegImmune | , | Changed name to GRI |
| Concerto HealthAI | , | Renamed ConcertAI |
| Constant Pharmaceuticals | , | Renamed Constant Therapeutics, Jan 2019 |
| Immerge BioTherapeutics | , | Founded 2000 |
| BioEcho Life Sciences | Cologne, Germany | Life Science Research Products |
| Andarix Pharmaceuticals | , | Not registered in MA, Nov 2022 |
| Trellis Bioscience | Redwood City, CA | Antibody Therapeutics |
| UCB Pharma | Boston, MA | Small Molecules, Biologics |
| N-Side | Cambridge, MA | Clinical Trial Supply Chain Software |
| Karmelsonix | , | Merged with Karmelsonix to become iSonea, 2011 |
| Sonde | Boston, MA | Voice-Based Diagnostics |
| Ananke Therapeutics | , | CEO gone Feb 2024; No website Apr 2023 - Nov 2023 |
| Abceutics | , | Acquired by Merck, Apr 2024, $208M |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Meddux | Boulder, CO | Medical Device Design, Development & Manufacturing Services |
| Mirari Biosciences | , | Website Gone, Nov 2016, One Employee |
| Ascenta Therapeutics | , | Gone |
| SunMed | , | Renamed AirLife |
| MetaSight Diagnostics | Rehovot, Israel | Diagnostics |
| Gamamabs Pharma | , | Assets Acquired by Exelixis, May 2021 |
| Charles River Laboratories | Mumbai, India | Research Animal Models and Preclinical Research |
| Ivantis | , | Website down Feb 2023; Acquired by Alcon, Jan 2022, $475M |
| Pyxis Oncology | Boston, MA | Antibody Immunotherapy |
| DiaMedica Therapeutics | Minnetonka, MN | Biologics |
| Spine View | , | Gone |
| Lila Sciences | Cambridge, MA | Scientific superintelligence platform and fully autonomous labs |
| Marck Biosciences | , | Renamed Amanta Healthcare, Sep 2014 |
| , | Acquired by Pacira BioSciences, Feb 2025; fka GeneQuine Biotherapeutics | |
| EliteImmune | Gaithersburg, MD | Customized reagents and services for monoclonal antibody development |
| AxisPharm | San Diego, CA | Bioanalytical Services, Proteomics, ADC Linker and Bioconjugation Services |
| Occlutech | Schaffhausen, Switzerland | Minimally-invasive Cardiac Devices |
| icometrix | Leuven, Belgium | Imaging AI |
| BioTalentum | Gödöllő, Hungary | Stem Cell Research & Services |
| Redpoint Research | , | Gone 2019 |
| Cytel | King of Prussia, PA | Clinical software, statistical services |
| Synthetic Gestalt | London, UK | AI Drug Discovery |
| RaNA Therapeutics | , | Renamed Translate Bio, Jun 2017 |
| Innocoll | , | Website down Dec 2024 - May 2025 |
| Zevra Therapeutics | Celebration, FL | Modifications of Existing Drugs |
| Sense Biodetection | , | Acquired by Sherlock Biosciences, Feb 2023 |
| Ypsomed | Solothurn, Switzerland | Self-injection systems |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| Phlebotics | , | 13 years old in 2021, founder/sole employee is part-time |
| MannKind | Danbury, CT | Inhalable Biologics, Gene Therapy |
| Mogrify | Cambridge, UK | Stem Cell Conversion |
| Optibrium | Cambridge, UK | Software solutions for small molecule design, optimization and data analysis |
| AntiOp | , | Tech sold Jun 2015 |
| Genkyotex | , | Acquired by Calliditas, Nov 2020 |
| Vericel | Ann Arbor, MI | Cellular Products |
| Heptares Therapeutics | , | Acquired by Sosei Group, Feb 2015 |
| Universal Diagnostics | Madrid, Spain | In-Vitro Diagnostic |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| AmtixBio | Hanam, Korea | Small Molecules, Sustained-release Technology |
| Arginox Pharmaceuticals | , | Apparently Gone |
| Pfizer | Groton, CT | Small Molecules, Biologics |
| Bristol Myers Squibb | New York, NY | Small Molecules, Biologics |
| PsiOxus Therapeutics | , | |
| Anutra Medical | , | Website down Jun 2023 - Dec 2023 |
| MilliDrop | , | Product Acquired by Gold Standard Diagnostics |
| Realize Therapeutics | Lake Bluff, IL | Cannabinoid-based & Microbiotic Therapeutics |
| Contego Medical | Raleigh, NC | Endovascular Devices |
| EmpathBio | , | |
| OnLume | Madison, WI | Fluorescence image-guided surgery |
| Oricula Therapeutics | , | Licensed sole product to Decibel Therapeutics, Sep 2018; No longer registered as business in WA |
| Bio-Rad | Irvine, CA | Research & Diagnostic Products |
| SignalRx Pharmaceuticals | , | Seems inactive, Dec 2023; no news 2018-2023 |
| Silarx Pharmaceuticals | , | Acquired by Lannett, Jun 2015 |
| Sytera | , | Merged with Sirion Aug 2006 |
| NovaDigm Therapeutics | , | Seems gone, Jul 2022 |
| Stratus Medical | Magnolia, TX | RF technology for pain |
| Vir Biotechnology | Bellinzona, Switzerland | Infectious disease therapies |
| Emmes | Rockville, MD | Clinical Research Organization |
| Xdynia | , | Merged with Tau Therapeutics to become Cavion, Aug 2014 |
| Sanomune | , | Acquired by Diamedica, Dec 2009 |
| NovaSignal | , | Renamed NeuraSignal, Jan 2024 |
| Advangen | , | Acquired by Cellmid, May 2013 |
| SystImmune | Redmond, WA | Novel therapeutic bi-specific, and multi-specific antibodies, antibody-drug conjugates |
| Reviva Pharmaceuticals | Cupertino, CA | Small Molecules |
| Johnson and Johnson Innovative Medicine | Raritan, NJ | Small Molecules, Biologics |
| Congenica | Cambridge, UK | Clinical genomic analytics platform |
| Protalix Biotherapeutics | Carmiel, Israel | Plant-derived Recombinant Therapeutics |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| Proxima Clinical Research | Houston, TX | Clinical Consulting |
| Mirata BioPharma | , | Website gone Jun 2020 - Mar 2021 |
| Portal Instruments | Cambridge, MA | Needle-free drug delivery platform |
| MeMed | Tirat Carmel, Israel | Test to distinguish bacterial from viral infections |
| Slayback Pharma | , | Acquired by Azurity Pharmaceuticals, Sep 2023 |
| Lung Bioengineering | , | Part of United Therapeutics |
| Aquapharm Biodiscovery | , | Acquired by Lallemand Dec 2013 |
| Viropro | , | Bankrupt 2015 |
| CreaGen | Woburn, MA | Drug Discovery Services |
| Bio-Path Holdings | Bellaire, TX | Antisense DNA therapeutics |
| Biodesy | , | Renamed BlueLight Therapeutics, Jun 2020 |
| 2X Oncology | , | Merged into parent company, Oncology Venture |
| Aastrom Biosciences | , | Changed name to Vericel, Oct 2014 |
| Frame Cancer Therapeutics | , | Acquired by CureVac, Jun 2022, €32M |
| Ceptaris Therapeutics | , | Bought by Actelion, Sep 2013, $250M |
| Kane Biotech | Winnipeg, MB | Biofilm Prevention Technology |
| Expedeon | , | Acquired by Abcam, Jan 2020; Acquired by SYGNIS, Jun 2017, €11.5M |
| Saluda Medical | North Yorkshire, UK | Spinal Cord Stimulation Device |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| NeuroHealing | , | Website down Feb 2024 - Jul 2024 |
| Aurora Biomed | Vancouver, BC | Liquid handling, elemental analysis, ion channel tech |
| 4TEEN4 Pharmaceuticals | Hennigsdorf, Germany | Antibody and diagnostic for dpp3, a biomarker of short-term organ dysfunction |
| Molecular Diagnostics, Inc | , | Renamed CytoCore |
| MGI Tech | Shenzhen, China | Sequencing |
| EnquBio | San Diego, CA | Contract Research & Services |
| Geistlich Pharma | Wolhusen, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Exemplify BioPharma | Cranbury, NJ | CMC laboratory and consulting services for small molecule programs - Process, Analytical, Formulation Development, QA, and Reg Affairs |
 |
Bordeaux, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Hybrigenics Services | , | Renamed ATON Group |
| Bio-Processing Alliance | , | Website now for a training company |
| amp Biosimilars | , | Seems to have pivoted to Crypto |
| Zucero Therapeutics | , | Website down Apr 2023 - Sep 2023 |
| Parion Sciences | Durham, NC | Mucosal Targets |
| ImmunoBiosciences | , | Website Gone 2-15-14. No info on what happened. |
| DoseCue | , | Website down Dec 2021 - Jul 2022 |
| Lumenis | Frankfurt am Main, Germany | Energy-based medical treatments |
| Cempra Pharmaceuticals | , | Merged into Melinta Therapeutics, Nov 2017 |
| Arch Oncology | , | Laid off all employees, website down Nov 2022 - Jan 2023; fka Tioma Therapeutics, also fka Vasculox |
| Nordic Pharma | Paris, France | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| Ally Pharma | , | Merged out of life sciences, Dec 2014 |
| , | Website down Sep 2025 - Feb 2026 | |
| Enable Medicine | Menlo Park, CA | Spatial Biology |
| Ultransonix | , | Acquired by Analogic, Mar 2013, $83M |
| BioCircuit Technologies | Atlanta, GA | Peripheral nerve monitoring and repair |
| Flaskworks | , | Acquired by Northwest Biotherapeutics, Sep 2020 |
| , | No news 2018 - May 2026 | |
| Piramal | Riverview, MI | CDMO |
| RxLogix | Aventura, FL | Pharmacovigilance Solutions |
| Q Therapeutics | Salt Lake City, UT | CNS Therapies |
| Bio-Rad | Philadelphia, PA | Tumor Markers |
| KMC Systems | , | Renamed HiArc, Jul 2025 |
| Gurus | Yerevan, Armenia | Clinical Data, Stats, Software |
| Miracor Medical | Awans , Belgium | Devices for Heart Disease |
| Cirrus Pharmaceuticals | , | Acquired by Kemwell, Jul 2013 |
| Metrochem | Hyderabad , India | APIs |
| Robocath | Rouen, France | Robotic Cardiovascular Treatments |
| Boston Strategic Corporation | , | Changed name to Strategia Therapeutics, Apr 2015 |
| Metenova | ZZ, Sweden | Mixers |
| REVA Medical | San Diego, CA | Minimally invasive medical devices |
| Premier Research Group | Morrisville, NC | Clinical research & consulting |
| Arima Genomics | Carlsbad, CA | Genomic Analysis Kits |
| NuGEN Technologies | , | Acquired by Tecan, Aug 2018, $54.4M |
| Tegmine Therapeutics | South SF, CA | Antibody Drug Discovery Platform |
| IGF Oncology | , | Shut down 2022 |
| InCarda Therapeutics | West Jordan, UT | Pulmonary drug delivery |
| Celera | , | Acquired by Quest Diagnostics, Mar 2011, $671M |
| Corvus Pharmaceuticals | Burlingame, CA | Immuno-oncology |
| Inscripta | , | Merged with Manu, Aug 2025 |
| Aptuit | , | Bought by Evotec, Aug 2017, $300M |
| PBL Interferon Source | , | Renamed PBL Assay Science |
| Sword Diagnostics | , | Website down Sep 2022 - Feb 2023 |
| Farmabios | , | Merged with Novasep & PharmaZell to become Axplora, Oct 2022 |
| Aurex Laboratories | , | Acquired by APNAR Pharma, Jul 2022 |
| Igenbio | Chicago, IL | Genomics, Gene Expression |
| PluroGen Therapeutics | , | Gone 2013 |
| Ataxion Therapeutics | , | Bought by Clal Biotech, Mar 2017, became Luc Therapeutics |
| ACCESS Oncology | , | Acquired by Keryx Biopharmaceuticals, Jan 2004 |
| Nirogyone Therapeutics | , | Renamed Norogy Therapeutics, Nov 2020 |
| Shorla Pharma | , | Renamed Shorla Oncology, Mar 2022 |
| |
Palo Alto, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| iLine Microsystems | Donostia-San Sebastian, Spain | POC Diagnostics |
| Nanobiotix | Paris, France | Nanoparticles |
| Toran Therapeutics | , | Never really took off, all employees gone Jan 2023; No info Jul 2021 - Aug 2021, Flagship Pioneering |
| , | Acquired by Frontage, Jul 2021 | |
| Summit Therapeutics | Menlo Park, CA | Utrophin modulation technology |
| Barrx Medical | , | Acquired by Covidien, Nov 2011, $325M |
| Somerville Development Partners | St Albans, UK | Regulatory affairs consultancy based in the UK, helping pharma and biopharma companies |
| 4SC | Planegg-Martinsried, Germany | Autoimmune & Cancer Small Molecules |
| Seattle Genetics | , | Renamed SeaGen, Oct 2020 |
| Pierre Fabre | Mazamet, France | Oncology, derm / cosmetics |
| Alphatec Spine | , | Renamed Atec Spine |
| LuBioScience | Zürich, Switzerland | Lab products and services |
| Dropprint Genomics | , | Acquired by Immunai, Mar 2021 |
| Firefly BioWorks | , | Acquired by abcam, Jan 2015, $28M |
| Amarantus Diagnostics | , | Merged into Avant Diagnostics, Mar 2016 |
| Vivelix Pharmaceuticals | , | Website gone Aug 2020 - Feb 2022 |
| Manus Biosynthesis | , | Renamed Manus Bio, Jun 2018 |
| Acandis | Pforzheim, Germany | Devices for Stroke |
| An-Con Genetics | , | Renamed Bovie Medical, Oct 1998 |
| Etubics | , | Rolled into ImmunityBio |
| Caliper Life Sciences | , | Bought by Perkin Elmer, Sep 2011, $600M |
| Xceleron | , | Acquired by Pharmaron, Jan 2017 |
| PepGen | Boston, MA | Peptide Conjugation Technology for Gene Delivery |
| ARKRAY | Minneapolis, MN | Clinical Diagnostics |
| CoBioRes | , | Website down Jul 2022 - Oct 2022 |
| DevaCell | , | LI gone Nov 2023; Business filings late Jan 2023 - Dec 2024 |
| Vasoptic Medical | Columbia, MD | Blood-flow Monitoring |
| Defyrus | , | Website gone Nov 2017 |
| Immunofoco | Shanghai, China | Autologous CAR-T cell product |
| GlycoFi | , | Bought by Merck, $400M, 2006 |
| Semorex | , | Website gone Dec 2017, single employee on LinkedIn |
| Lung LLC | , | Renamed Lung Biotechnology |
| Jemincare Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| ArTara Therapeutics | , | Renamed Protara Therapeutics, May 2020 |
| Chiesi | Colombes, France | Small Molecules, Biologics, Orphan Drugs |
| CytoVeris | , | Merged with Lumeda to become OncoLux, Jun 2025 |
| Adams Respiratory Therapeutics | , | Acquired by Reckitt Benckiser, Dec 2007, $2.3B |
| Agendia | Irvine, CA | Breast Cancer Assay |
| Microsize | Quakertown, PA | Microionization CDMO |
| , | Website down Oct 2025 - Feb 2026 | |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Immetacyte | , | Renamed Cellular Therapeutics Ltd, Mar 2018 |
| Avertix Medical | Eatontown, NJ | Implant to detect heart problems |
| Anadys Pharmaceuticals | , | Acquired by Roche 2011 |
| CiMaas | Maastricht, Netherlands | Cellular Immunotherapy |
| Profluent | Emeryville, CA | AI Protein Creation |
| Altermune Technologies | , | Tech acquired by Centauri Therapeutics, Jan 2016 |
| Essentialis Therapeutics | , | Merged with Capnia, Mar 2017 |
| OptiVia Medical | , | Website looks pretty terrible |
| hVIVO | London, UK | Viral Services |
| inDNA Research Labs | , | Shut down 2015 |
| Obecure | , | Inactive, no info |
| Acceler8 Clinical Research | Chester, UK | Clinical Research |
| Amomed Pharma | , | Acquired by AOP, Jan 2022 |
| Innate Immunotherapeutics | , | Acquired Amplia Therapeutics, took its name |
| Gener8 | San Jose, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Zai Lab | Hong Kong, China | Small Molecules |
| AvenCell Therapeutics | Watertown, MA | CAR-T, T cell engaging bispecific antibody |
| A&E Medical | , | Acquired by Zimmer Biomet, Dec 2020, $250M |
| Bioprocessing Inc. | , | Bought by Bio-Rad |
| Mirina Corp | , | Changed name to Groove Biopharma, Jun 2011 |
| NeoVista | , | Gone 2011 |
| POMS | Redmond, WA | Web-based Manufacturing Execution System |
| Nostrum Pharmaceuticals | , | Website from 2008 |
| Cytogel Pharma | Darien, CT | Drug Delivery Technologies |
| Prolor Biotech | , | Acquired by OPKO, Aug 2013, renamed Opko Biologics |
| ViroStat | , | Acquired by Medix Biochemica, Nov 2023 |
| Collgard Biopharmaceuticals | , | Gone |
| Medivation | , | Bought by Pfizer, Oct 2016, $14B |
| Knome | , | Acquired by Tute Genomice, Nov 2015 |
| Sortera bio | Cambridge, UK | AI Biologics Discovery |
| ANTITOXIN | Bammental, Germany | Blood grouping reagents |
| AgenTus Therapeutics | , | Renamed MiNK Therapeutics, Aug 2021 |
| Corixa | , | Bought by GSK, 2005; closed 2006 |
| Kindeva Drug Delivery | St. Paul, MN | Drug Delivery CDMO |
| Gema Biotech | , | Acquired by AMEGA biotech, early 1990s |
| Huons | Seongnam, Korea | Small Molecules |
| Hengrui Therapeutics | , | Renamed Luzsana, May 2022 |
| Amagma Therapeutics | , | Being folded into new company, Feb 2023 |
| ViroMed | , | Renamed Helixmith |
| Modus Therapeutics | Stockholm, Sweden | Heparin Derivatives |
| Genstruct | , | Now Selventa |
| Quellthera | , | Subsumed into Liveleaf |
| Simbec-Orion Group | Mid Glamorgan, UK | Clinical Research |
| Grunenthal | Aachen, Germany | Small molecules |
| ImmunoScience | , | Website closed Sep 2022 - Nov 2022 |
| Smart4Diagnostics | Munich, Germany | Diagnostics |
| ViiV Healthcare | Durham, NC | 10 HIV Treatments |
| Solstice Oncology | , | |
| Avistone | Beijing, China | Precision Oncology |
| Zephyrus Pharmaceuticals | , | Might be Zephyrus Biosciences |
| Cernostics | , | Acquired by Castle Bioscience, Dec 2021, up to $30M + $50M Milestones |
| Fulcrum Pharma | , | Now Aptiv Solutions |
| Arcturus Therapeutics | San Diego, CA | Lipid nanoparticle (LNP) mRNA drug delivery systems |
| Idyllic Pharmaceuticals | , | Founder gone 2015, no add'l info |
| Regeneron | Tarrytown, NY | Small Molecules, Biologics |
| ABTECH Scientific | , | Website absurdly outdated, Dec 2020 - Jan 2022 |
| Pharmidex | London, UK | Drug discovery CRO. GLP/non-GLP services, DMPK studies, therapeutic models and GLP toxicology |
| GyneConcepts | , | No news 2016 - Nov 2024 |
| BioLogo | , | Acquired by Nordic MUbio, Mar 2018 |
| Kynos Therapeutics | , | Acquired by Dr. Falk Pharma, Oct 2024 |
| Boston Scientific | Maple Grove, MN | Medical Devices |
| CryptoMedix | , | No updates Jan 2022 - Jul 2025 |
| Cogentis Therapeutics | , | No news 2017-2023 |
| Alexar Therapeutics | , | Renamed Ralexar Therapeutics, Mar 2016 |
| Panag Pharma | , | Website down Dec 2024 - Mar 2025; Acquired by Tetra Biopharma, May 2019 |
| Medical Instrument Development Laboratories | San Leandro, CA | Ophthalmic devices |
| Biogelx | , | Website down Sep 2021 - Feb 2022 |
| Heraeus Medical | Kolkata, India | Medical Devices |
| Human Metabolome Technologies | Boston, MA | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| CEND Therapeutics | , | Merged with Caladrius Biosciences, Apr 2022, to become Lisata Therapeutics; fka DrugCendR |
| GeneoDx | , | Website gone Oct 2019 |
| Evergen | Glencoe, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Fractyl Laboratories | , | Renamed Fractyl Health |
| PCI Pharma Services | Großbeeren, Germany | Contract Manufacturing, Services |
| FzioMed | San Luis Obispo, CA | Surgical Adhesion Barrier |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Schrodinger | New York, NY | Computation Drug Discovery Platform |
| RareCyte | Seattle, WA | Rare Cell Analysis |
| Folio Biosciences | , | Merged with Conversant Bio, Renamed Folio Conversant, then merged into Discovery Life Sciences, Oct 2018 |
| Synendos Therapeutics | Basel, Switzerland | Small molecule for cns disorder |
| Terumo Medical | Elkton, MD | Medical Devices |
| Sonosite | , | Acquired by FujiFilm, Dec 2011 |
| Ibex Preclinical Research | Logan, UT | Preclinical Research |
| Health Gene Technologies | , | Website down Dec 2020 - May 2021 |
| Exalenz Bioscience | , | Acquired by Meridian Bioscience, Apr 2020 |
| 9 Meters Biopharma | , | Bankrupt Jul 2023; fka Innovate Biopharmaceuticals, Merged with RDD Pharma Apr 2020 |
| Avesthagen | Bangalore, India | Systems Biology Platform |
| Spinnovation Biologics | , | Acquired by Sinensis Life Sciences, Oct 2014 |
| MNM Bioscience | , | Website down Jun 2023 - Sep 2023; Claim Boston/Delaware, but everyone in Poland Apr 2022 |
| ProPharma Group | Bozeman, MT | Consulting |
| Paragon Medical | , | Acquired by AMETEK, Oct 2023; Previously part of MW LifeSciences |
| Almirall | Barcelona, Spain | Small Molecules |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Gyros Protein Technologies | Uppsala, Sweden | Bioassay Equipment |
| Precision for Medicine | Frederick, MD | Services / Consulting |
| DNAtrix | , | Gone late 2023 |
| KynderMed | , | Renamed Prena |
| Somnus Therapeutics | , | Probably gone, not sure what happened |
| , | Acquired by Medicover, Apr 2026 | |
| DFE Pharma | Goch, Germany | Excipients |
| TissueGene | , | Renamed Kolon TissueGene, Mar 2018 |
| Evestia Clinical | Hertfordshire, UK | Clinical Research & Services |
| Navinta | Ewing, NJ | Generics |
| P95 | Leuven, Belgium | Vaccine and Infectious Clinical Research |
| Isoray Medical | , | Meregd with Viewpoint Molecular Targeting to become Perspective Therapeutics, Feb 2023 |
| West Pharma | Singapore, Singapore | Pharmaceutical Supplier |
| Aerpio Therapeutics | , | Merged with Aadi Bioscience, Aug 2021 |
| Diagnoplex | , | Assets acquired by Novigenix, Feb 2015 |
| Aurelia Bioscience | , | Acquired by Chernwood Molecular, Jun 2021 |
| Amrita Therapeutics | , | Seems gone |
| Fusion Genomics | Richmond, BC | Developing a cheaper, faster, more sensitive, single diagnostic NGS test for all infectious diseases |
| Abraxis Bioscience | , | Bought by Celgene, Jun 2010, $2.9B |
| Stemnovate | Cambridge, UK | Research Cells |
| PerSeptive Biosystems | , | Acquired by Perkin-Elmer, 1998 |
| SOPHiA GENETICS | Boston, MA | Clinical Next Gen Sequencing Dry Lab Service |
| BioGenics | , | Website down early 2021 - Apr 2022 |
| Zydus Therapeutics | Pennington, NJ | Small Molecules |
| , | Assets acquired by Tivic, Dec 2025; fka Scorpion Biological Services | |
| CELLphenomics | , | Acquired by GSK, Feb 2025 |
| Revalesio | Tacoma, WA | Proprietary charge-stabilized nanostructure (CSN) technology |
| Dexa Medica | Tangerang, Indonesia | Small Molecules |
| CytoImmune Therapeutics | Southbank, Australia | Cancer Immunotherapy |
| ProMIS Neurosciences | Toronto, ON | Neurodegenerative Therapies |
| Kanyos Bio | , | Acquired by Anokion, Sep 2019 |
| Pierce | , | Part of Thermo Fisher |
| Versicor | , | Changed Name to Vicuron Pharmaceuticals |
| Reverse Medical Corp | , | Bought by Covidien, 08/14 |
| Viagene | , | Acquired by Chiron, Apr 1995, $95M |
| Antibodies Incorporated | Davis, CA | Antibodies, Assays, Development Services, Diagnostic kits, etc.. |
| Novasite Pharmaceuticals | , | Business forfeited according to CA SOS |
| Unizyme | , | Virtual, No progress Mar 2015 - Jul 2019 |
| Oncozyme Pharma | , | Renamed Verlyx Pharma, 2015 |
| Idogen | , | Website gone Nov 2023; Strategic Alts, Apr 2023 |
| Burst Diagnostics | Fort Collins, CO | Chemiluminescent Diagnostic Platform |
| Amivas | Waterford, Ireland | Antimalarial |
| Unilife | , | Bankrupt, Apr 2017 |
| HemostOD | St. Sulpice, Switzerland | Platelet Manufacturing |
| Annapurna | , | Merged into Avalanche Biotechnologies, Feb 2016, Renamed Adverum Biotechnologies |
| Protein Dynamic Solutions | Wakefield, MA | Protein Characterization for Drug Development |
| GSK | Marietta, PA | Small Molecules, Vaccines, Biologics |
| Alpha Innotech | , | Acquired by Cell Biosciences, Sep 2009 |
| Ethismos Research | , | Website gone Mar 2023; working on foods |
| Neuroptix | , | Renamed Cognoptix |
| Aptamer Sciences | Gyeonggi, Korea | Protein analysis technology |
| EpiBone | Brooklyn, NY | Personalized Bone Grafts |
| Molecular Response | , | Acquired by Bioduro, Mar 2018 |
| , | Renamed Aspen Neuroscience | |
| DeepSight Technology | Santa Clara, CA | Next-gen Ultrasound |
| Sage Science | Beverly, MA | DNA Fractionation |
| Limerick Bio | , | Gone 2011 |
| CMC Biologics | , | Now part of AGC Biologics |
| Tyber Medical | Bethlehem, PA | Orthopedic Devices |
| Biotagenics | , | Renamed MedBiome |
| Herophilus | San Francisco, CA | Phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases |
| Alltrna | Cambridge, MA | tRNA therapies |
| Nosopharm | , | Website down Dec 2024 - Feb 2025, the taken over by scammers |
| Engine Biosciences | San Mateo, CA | AI & genomics |
| Versatile Biology Lab | , | Website down Nov 2023 - Mar 2024 |
| Tinoro | , | Website gone, no business filings since 2017 as of Oct 2020 |
| Secura Bio | Berkeley Heights, NJ | Acquisition & Worldwide Commercialization |
| OXiGENE | , | Renamed Mateon Therapeutics, Jun 2016 |
| Bard1 | , | Renamed INOVIQ |
| Xtal Concepts | Hamburg, Germany | Measuring instruments for the characterization of nano- and microparticles in liquids |
| Inference | Chesterbrook, PA | Clinical Trial Services |
| BioCanCell | , | Renamed Anchiano Therapeutics, Aug 2018 |
| Beloteca | San Diego, CA | Generics & 505(b)(2) drugs |
| Inspirata | North York, ON | Cancer Insights |
| Amnicell | , | Website down Dec 2022 - Apr 2023 |
| Microplate Dx | Glasgow, UK | UTI Diagnosis |
| Fedora Pharmaceuticals | , | No news 2020 - Mar 2025 |
| HB Therapeutics | , | No website, Dec 2018 - Dec 2020 |
| Chemir Analytical Services | , | Acquired by EAG, 2011 |
| The Tech Group | , | Acquired by West Pharma, May 2016 |
| Metheor Therapeutics | , | Shut down, Dec 2018 |
| Biovian | , | Merged with 3P Biopharmaceuticals, Feb 2024 to become 3PBIOVIAN |
| Aucta Pharmaceuticals | Shanghai, China | 505(b)(2) |
| DNASense | , | Merged with Clinical-Microbiomics, MS-Omics, CosmosID to become Cmbio, Oct 2023 |
| InterGenetics | , | Assets auctioned |
| Abbey Moor Medical | , | Product sold to SRS Medical, Nov 2012 |
| ACROBiosystems | Cambridge, MA | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Pharmatech | , | Acquired by Caris Life Sciences, May 2019 |
| AmpleLogic | Madhapur , India | Provider of GAMP Solutions to the Life Science Industry |
| Pannex Therapeutics | New York, NY | Panx1 Targeting Therapeutics |
| Ensera | Lakeland, FL | Device Manufacturing, Pharmaceutical Packaging |
| Integra LifeSciences | Saint Priest, France | Medical Devices |
| Hipro Biotechnology | Shijiazhuang, China | Diagnostic Manufacturing |
| XRpro Sciences | , | Renamed Icagen Jul 2015, Purchased Icagen (1) assets from Pfizer |
| Code Biotherapeutics | Hatfield, PA | DNA-based Gene Therapy Vector |
| Adeptrix | Beverly, MA | Bead Assisted Mass Spec |
| Nexgenix | , | Doesn't seem active as of Mar 2015 |
| , | Website down Jul 2025 - Dec 2025 | |
| Anitoa Systems | Hangzhou, China | Diagnostic Systems |
| ChemDiv | San Diego, CA | Contract Development, Clinical Trial Monitoring |
| Biocoat | Horsham, PA | Medical Device Coatings |
| Aderis Pharmaceuticals | , | Acquired by Schwarz Pharma, Jul 2005 |
| Platelet BioGenesis | , | renamed PlateletBio |
| Biobeat | Petah Tikva, Israel | Cuffless Blood Pressure Monitor |
| Unleash Immuno Oncolytics | , | Website down Sep 2021 - Feb 2022 |
| Celluris | Monthey, Switzerland | CAR T Cell Therapy |
| Centocor | , | Renamed Janssen Biotech |
| Neurogene | New York, NY | Genetic Therapies |
| Quartesian | , | Acquired by Veranex, Jun 2021 |
| Aber Instruments | Aberystwyth, UK | Dielectric spectroscopy for live cell density readings |
| Ziylo | , | Bought by Novo Nordisk, Jul 2018, up to $800M |
| NRTK Biosciences | , | No website Dec 2020 - Jul 2024; Mentioned in NatBio, Dec 2020 |
| Crossbeta Biosciences | , | Website down Nov 2024 - Jun 2025; Spins out all products |
| , | Renamed Envue, Feb 2026 | |
 |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Sai Life Sciences | Hyderabad , India | Contract Development & Manufacturing |
| PowderMed | , | Acquired by Pfizer 2006 |
| AbbVie | Dublin, Ireland | Medical Devices |
| Xeno Biosciences | , | IP being acquired by LPOXY Therapeutics, Jan 2025 |
| Proteintech | Rosemont, IL | Research Antibodies |
| , | No news Jun 2021 - Jan 2026 | |
| C2i Genomics | , | Acquired by Veracyte, Feb 2024, $70M +$25M milestones |
| Scientific Diversified Industries | , | Website down Dec 2021 - Apr 2022 |
| OrphoMed | , | Shut Down 2022 |
| Apicore | Gujarat, India | API Development & Manufacturing |
| Echo Biotech | Beijing, China | Exosome Products & Services |
| InBrain Pharma | Lille, France | Neurodegenerative Treatments |
| JRF GLOBAL | Valvada , India | Non clinical GLP research services |
| DiaMex | , | Acquired by LGC, Dec 2024 |
| The Antibody Lab | Vienna, Austria | Contract Antibody Work |
| IgY Immune Technologies & Life Sciences | , | Renamed IGY Life Sciences |
| Prominex | San Diego, CA | POC Diagnostics |
| Nano Precision Medical | , | Merged with Second Sight to become Vivani Medical, Aug 2022 |
| BreviTest Technologies | , | Website down Jun 2023 - Dec 2023 |
| Tamarind Bio | San Francisco, CA | Computational Tools |
| Hyperion Therapeutics | , | Bought by Horizon Pharma Mar 2015 $1.1B |
| Genome & Company | Suwon, Korea | Microbiome, Antibody Therapies |
| Lyophilization Technology | Warminster, PA | Contract Lyophilization |
| , | Website down Jan 2026 - May 2026 | |
| Gordagen Pharmaceuticals | , | Bankrupt, dissolved Oct 2017 |
| Bertis | Gwacheon-si, Korea | Cancer Diagnostics, Diagnostic Platform |
| Helicos Biosciences | , | Chapter 11 Bankruptcy Nov 2012, Assets purchased by SeqLL |
| West Pharma | São Paulo, Brazil | Pharmaceutical Supplier |
| CardiAQ Valve Technologies | , | Acquired by Edwards Life Sciences, Jul 2015, $350M + $50M milestones |
| Cygnus Therapeutic Systems | , | Dissolved Nov 2005 |
| Pixelgen Technologies | Stockholm, Sweden | 3-dimensional spatial mapping of cell surface proteins |
| Fast-Diag | , | Website down Jun 2023 - Dec 2023 |
| SmooFi | , | Changed name to NuLife Sciences, Dec 2016 |
| TheraSource | , | No news Jul 2017 - Feb 2024 |
| CuraGen | , | Bought by Celldex 2009, $94.5M |
| Trailhead Biosystems | Beachwood, OH | Specialized Human Cells |
| IMMY | Norman, OK | Fungal Diagnostics |
| TransEnterix | , | Renamed Asensus Surgical, Feb 2021 |
| Nexus Dx | , | Merged into Sphingotec, May 2018 |
| Dermagen | , | Website Gone, scammy sites with similar name |
| Triad Life Sciences | , | Acquired by Convatec, Mar 2022 |
| RareGen | , | Acquired by Liquidia, Jun 2020 |
| , | Renamed Definium Therapeutics, Jan 2026 | |
| iSpecimen | Woburn, MA | Biospecimen Procurement |
| GenePharm | Pallini, Greece | Pharmaceutical Contract Manufacturing |
| Existence Genetics | , | Bankrupt Dec 2012 |
| , | Website down Oct 2025 - Feb 2026 | |
| BBOT | South SF, CA | RAS-targeted small molecules |
| Synplogen | Kobe, Japan | Gene Therapy production, sequence design |
| Bamboo Therapeutics | , | Bought by Pfizer, Jul 2016, $150M + milestones |
| Teleflex Medical | Shanghai, China | Surgical and Medical Devices |
| Oculis | Lausanne, Switzerland | Dexamethasone for Ocular Delivery |
| , | Merged with Vizgen, Oct 2024 | |
| Charles River Laboratories | Frederick, MD | Research Animal Models and Preclinical Research |
| diaDexus | , | Filed Chapter 7, Jun 2016 |
| Kuros Biosciences | Schlieren, Switzerland | Medical Devices |
| Biodesix | Louisville, CO | Molecular Diagnostics |
| Gilero | Pittsboro, NC | Contract manufacturing of medical device & drug delivery systems |
| Maverix Biomics | San Mateo, CA | Next Generation Sequencing data analysis |
| AOP Orphan Diseases | Birmingham, UK | Orphan disease treatments |
| Shenandoah Biotechnology | , | Acquired by Fujifilm Irvine Scientific, Mar 2022 |
| Quanta Biosciences | , | Renamed QuantaBio |
| Bend Bioscience | Bend, OR | Clinical Manufacturing, Development |
| CollaGenex | , | Acquired by Galderma, Feb 2008, $420M |
| Balmes Transplantation | , | Renamed Kinapharma, 2020 |
| Alladapt Immunotherapeutics | , | Shut down Apr 2024 |
| X2 Pharma | , | Website Gone |
| Multiplicom | , | Acquired by Agilent, €68M, Dec 2016 |
| Cerus | Concord, CA | Medical Devices, Biotechnology |
| Axo Neurotech | San Francisco, CA | Neural Interfaces |
| Medical Device Success | , | Website down Nov 2023 - Mar 2024 |
| Immulogic Pharmaceutical | , | Gone, 1999 |
| Gaelic Laboratories | Clonmel, Ireland | Beta-Lactam manufacturing, Analytical Testing, Batch Release |
| Avicor Biotech | , | No news Jun 2020 - Feb 2025 |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| CombiMatrix | , | Acquired by Invitae, Nov 2017 |
| Vesuvius Therapies | , | New in 2015, quickly disappeared from VC website |
| Akrimax | , | Website password protected Apr 2020 - Oct 2020 |
| Acylin Therapeutics | , | Assets sold 2014 |
| MolPlex | , | Insolvent, 2016 |
| Machaon Diagnostics | Berkeley, CA | Clinical reference lab |
| Lewis and Clark Pharmaceuticals (2) | , | CEO gone in 2017, still on website Feb 2023; Merged into Inspyr Therapeutics, Sep 2017 |
| Vipergen | Copenhagen, Denmark | Small Molecule Discovery Using DNA-Encoded Chemical Libraries |
| Wuxi Griffin Pharmaceuticals | , | Website down Jul 2024 - Sep 2024 |
| Visiopharm | Hørsholm, Denmark | AI Research - Diagnostics, Pathology |
| Yellow Jersey Therapeutics | , | Acquired by J&J, Jul 2024, $1.25B |
| Xencor | Pasadena, CA | Antibody Discovery |
| Aslan Pharmaceuticals | , | Liquidating Jul 2024 |
| Ekso Bionics | San Rafael, CA | Exoskeleton |
| Mitim | , | Acquired by Recipharm, Feb 2016, $75.5M |
| Aestus Therapeutics | , | Gone late 2014 estimated |
| Advanced Biologics | , | Dissolved, Dec 2017 |
| FORESIGHT&LINX | , | Website down Apr 2021 - Sep 2021 |
| Elpis Biopharmaceuticals | Lexington, MA | Cellular & Biologic Therapies |
| Venebio | Glen Allen, VA | Consultants |
| Q32 Bio | Waltham, MA | Biologics to restore healthy immune regulation |
| Sciele Pharma | , | Bought by Shionogi |
| Link Medical | Oslo, Norway | Clinical Research, Regulatory |
| Vioquest | , | Fka Chiral Quest, effectively gone |
| Uptake Medical | San Jose, CA | Non-surgical, non-implant therapy to improve breathing |
| Achaogen | , | Chapter 11 bankruptcy, Apr 2019 |
| TMC Pharma Services | Hampshire, UK | Global pharma/biotech services company, providing full product development from preclinical through to marketing |
| Chelsea Therapeutics | , | Acquired by Lundbeck, Jun 2014, up to $658M |
| Xyphos | South SF, CA | Cell-based cancer therapies |
| Alacrita | Cambridge, MA | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| Meissner | Camarillo, CA | Lab Systems |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| , | Website down Nov 2025 - Apr 2026 | |
| Novo Nordisk | Fukushima, Japan | Diabetes, obesity, liver disease and other therapeutic areas |
| Alchemia | , | Gone, late 2017 |
| Antyra | , | Gone |
| CeGaT | Tubingen, Germany | Diagnostic Genetic Sequencing |
| Color | Burlingame, CA | Genetic testing, direct to consumer |
| ARC Medical Design | , | Acquired by Olympus, Aug 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| Phaze Clinical Research | Athens, Greece | Clinical Research, Consulting |
| Avania | Collingwood, Australia | Medical Device Clinical Research |
| 4basebio | Cambridge, UK | Synthetic DNA Constructs |
| MileCell Biotech | San Diego, CA | Cells, Matrices, Reagents |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| ZYUS Life Sciences | Saskatoon, SK | Cannabinoid-based therapies |
| ProNeurogen | , | CEO left Dec 2020 seems like only academic founder is left, location is a residence |
| Lucena | , | Failed |
| Micregen | Berkshire, UK | Mesenchymal Stem Cell-derived Secretomes |
| Anthem Biosciences | Bangalore , India | Contract Research |
| Lexitas | Durham, NC | Ophthalmic Clinical Research |
| RaySearch Laboratories | New York, NY | Cancer Research Software |
| StemiRNA Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Accelovance | , | Merged with Linical, took name, Jul 2018 |
| Biolojic Design | Cambridge, MA | AI-based Multibody technology |
| Celerion | West Conshohocken, PA | Clinical Research |
| Apollo Medical Devices | , | Website expired Nov 2019 - Feb 2020 |
| Eucure Biopharma | Beijing, China | Therapeutic Antibodies |
| Panacos | , | Believe they are inactive |
| Clina Research | , | Website gone Jul 2023 |
| Tusk Therapeutics | , | Acquired by Roche, Sep 2018, $81M + $679M milestones; Team spinning out into new company Black Belt Therapeutics |
| Transport Pharmaceuticals | , | Purchased by NitricBio, Oct 2009 |
| Batavia Biosciences | Woburn, MA | Early Stage Product Development Services |
| CureMeta | , | Failed to file business docs, dissolved Jun 2019 |
| Neurotargeting | , | Website gone Oct 2019, company founded 2007 |
| KORU Medical Systems | Mahwah, NJ | Infusion Systems |
| EndoTheia | Nashville, TN | Next-generation devices for flexible endoscopy |
| ChronTech Pharma | , | Became real estate company |
| Raytone Bio | , | |
| , | Subsumed into Synoptics | |
| E&O Laboratories | Bonnybridge, UK | Microbiological Culture Media |
| Igenomix | Buenos Aires, Argentina | Contract genetic testing for reproductive health; covid-19 pcr |
| Viridian Therapeutics | Waltham, MA | Monoclonal Antibodies, Fc Fragments |
| NEOMED-LABS | , | Merged with Pacific Biomarkers, Nov 2018 |
| Cambrex | Charles City, IA | Small Molecules Research, Development & Manufacturing Services |
| Develco Pharma | Pratteln, Switzerland | Generics |
| Resolvyx Pharmaceuticals | , | Website Gone, Jan 2016; no employees on LinkedIn |
| Celadon Laboratories | , | Renamed DNA Analytics, Sep 2020 |
| Radient Pharmaceuticals | , | Insolvent but ex-employees are running it as consultants |
| Aestus Pharmaceuticals | , | Renamed Alanza |
| Resilience Therapeutics | , | Website down Feb 2021 - Jul 2021; Not much info out there, May 2018 - May 2020; one employee and a board; residential address |
| OrSense | Raleigh, NC | Blood Analytes Monitor |
| Vicarious Surgical | Waltham, MA | Surgical Robotics |
| Lumenis | Yokneam, Israel | Energy-based medical treatments |
| Bellicum Pharmaceuticals | , | Shut down Mar 2024; Strategic Alts, Mar 2023 |
| RenovaCare | , | Website has nothing, no employees on Linkedin, doesn't seem serious Feb 2024 |
| Prazer Therapeutics | Seoul, Korea | Targeted Protein Degradation Drug Discovery Platform |
| Arpeggio Biosciences | Boulder, CO | AI Drug Screening Platform |
| Provisio Medical | San Diego, CA | Endovascular Devices |
| Rigenerand | , | Acquired by Evotec, Jul 2022, €23M |
| Latent Labs | Cheshire, UK | AI models to design and optimize proteins |
| Abcyte Therapeutics | , | No website Jan 2022, Marked as closed on Google, but active in CA database Nov 2020 - Jan 2022 |
| Tusker Medical | , | Acquired by Smith & Nephew, Jan 2020 |
| Follicum | , | Merged with Coegin Pharma, Feb 2022; Entire pipeline on hold Sep 2021 |
| Trilobio | San Francisco, CA | Lab Automation |
| Mesa Biotech | , | Acquired by Thermo Fisher, Mar 2021, $550M |
| Prolytix | Essex Junction, VT | Contract Biologics Research & Development |
| CosmosID | , | Merged with Clinical-Microbiomics, DNASense, MS-Omics to become Cmbio, Oct 2023 |
| Intelligencia | Athens, Greece | AI-Drug Discovery |
| SeQure Dx | , | Acquired by MaxCyte, Jan 2025 |
| Patara Pharma | , | Shut down Sep 2018 to become Respivant |
| ICU Medical | San Clemente, CA | Disposable medical products |
| Aliri | Salt Lake City, UT | Contract Mass Spec |
| Invivyd | Waltham, MA | Therapeutic Antibodies |
| Pisgah Labs | , | Acquired by IPCA Pharmaceutical, Jan 2018 |
| OncoCell MDx | , | Renamed Immunis.AI |
| LGM Pharma | Modiin, Israel | APIs, CDMO Services |
| , | Acquired by Scantox, Sep 2024 | |
| Celnova Pharma | Buenos Aires, Argentina | Regional Therapeutics |
| Isabi | New York, NY | Cancer Genome and Transcriptome Analysis |
| ReViral | , | Acquired by Pfizer, Jun 2022, up to $525M |
| ThauMDx | , | Closed down 2003, out of cash |
| Sepragen | Union City, CA | Chromatography, Bioreactors |
| Phico Therapeutics | , | Liquidating, Apr 2024 |
| G & H ITL | Ilminster, UK | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Volta Medical | Providence, RI | Artificial intelligence to revolutionize interventional cardiac electrophysiology |
| AbVitro | , | Bought by Juno Therapeutics, Jan 2016, $125M |
| Radikal Therapeutics | , | Pivoted to Services, Changed name to Salzman Group, Mar 2018 |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Ceronco Biosciences | , | Gone 2015? |
| , | Acquired by Takara Bio, Jan 2025 | |
| Alliance Spine | San Antonio, TX | Spinal implants |
| RemeGenix | , | Business Forfeited in MD, Nov 2008 |
| Ability Biomedical | , | Acquired by Medarex, $4.7M, Jul 2004 |
| Cognis Corp | , | Acquired by BASF 2010 |
| Consanance | Krakow, Poland | Medical Device Design & Manufacturing |
| Jiuzhou Pharma | Kanagawa , Japan | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| IROC Inocross | , | Assets acquired by Avedro, Sep 2014 |
| CONTINUUS Pharmaceuticals | Woburn, MA | Continuous small molecule manufacturing |
| Acousia Therapeutics | Tübingen , Germany | Small Molecules for Hearing Loss |
| AngioCure | , | Employees all gone, Nov 2017 |
| Aurobindo Pharma | Hyderabad, India | Bulk Active Manufacturer |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| , | Renamed EVA Therapeutics, Apr 2026 | |
| AboleIIs Pharma | Nantes, France | Monoclonal Antibody |
| Medreich | Bengaluru, India | CDMO |
| Radar Therapeutics | , | Smart Programmable Medicines Using Molecular RNA Sensors |
| Pin Therapeutics | Seongnam, Korea | Protein Degradation Therapeutics |
| , | CEO left, seems defunct Dec 2025; Website down Nov 2025 - Jan 2026; fka Ceremedix | |
| Warnex | , | Merged into DIAGNOS Inc |
| CyteGen | , | 2015 founded, website never active |
| Ergomed | Prague, Czech Republic | Clinical Research |
| Meraqi Medical | , | Acquired by Viant Medical, Sep 2019 |
| Clinimetrics | , | Acquired by Omnicare Dec 2004; Now Theorem Clinical Research |
| Chattem | , | Bought by Sanofi, Dec 2009, $1.9B |
| Adicet Bio | Redwood City, CA | Immunotherapies |
| Elixirgen Scientific | , | Subsumed into Ricoh Sciences |
| Antidote Technologies | North Miami Beach, FL | Clinical Recruiting |
| Menlo Therapeutics | , | Renamed Vyne Therapeutics, Sep 2020 |
| Fiagon AG Medical Technologies | Hennigsdorf, Germany | Electromagnetic Navigation for Surgery |
| Ascletis Pharma | Hangzhou, China | RNAi Therapeutic |
| Stelis Biopharma | , | Renamed OneSource, Sep 2024 |
| Plus Therapeutics | Austin, TX | Radiotherapy |
| InVera Medical | Galway, Ireland | Treatment for venous disease |
| IMBiologics | Suwon, Korea | Antibody Therapeutics |
 |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| LexaGene | , | Chapter 7 bankruptcy, Feb 2023 |
| Daicel Arbor Biosciences | Ann Arbor, MI | Kits, reagents, and technologies for genetics and synthetic biology |
| Promiliad Biopharma | , | No updates since 2008 as of Sep 2020 |
| NextCODE Health | , | Acquired by WuXi PharmTech, Jan 2015, $65M; rebranded as WuXi NextCODE |
| BTS Research | , | Renamed BioLegacy Research, Jul 2025 |
| Encore Pharma | , | Website exists, no updates since 2001 as of Jun 2019 |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Aevi Genomic Medicine | , | Acquired by Cerecor, Feb 2020, $15.6M + $6.5M Milestones |
| Brains On-Line | , | Acquired by Charles River, Aug 2017 |
| PARI Pharma | Starnberg, Germany | Nebulizer Product Development Services |
| SciNeuro Pharmaceuticals | Rockville, MD | Neuro Treatments |
| Micronoma | , | CEO Gone Sep 2024; Website down Sep 2024; Filings late Jun 2022 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| CENTOGENE | Rostock, Germany | Genetic Testing |
| Ativa Medical | , | Renamed Immune IQ? |
| Bastion Biologics | , | Closed on Google Aug 2022 |
| Ardana Biosciences | , | Bankrupt, Jul 2008 |
| Apellis Pharmaceuticals | Zug, Switzerland | Cyclic peptide analog |
| ImmuNext | , | Website gone Feb 2025 |
| Trovex BioTherapeutics | , | No website, Nov 2018 - May 2023; "Stealth" |
| Pareto Bio | , | Website down Mar 2024 - Jul 2024; fka Consortia Therapeutics |
| Paloma Pharmaceuticals | , | Acquired by Stratus Media, Renamed RestorGenex, Mar 2014 |
| AngioDynamics | Queensbury, NY | Array of Medical Devices |
| Henogen | , | Acquired by Novasep, Jul 2009 |
| Ocis Biotechnology | , | |
| mBio Diagnostics | , | Merged with Brava Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| Valneva | Vienna, Austria | Biologics Manufacturing |
| , | Renamed Athens Bioscience, Mar 2026 | |
| OncoSignature | , | Renamed Acrivon Therapeutics, May 2018 |
| Hamari Chemicals | , | Website down Nov 2022 - Mar 2023 |
| Inkspace Imaging | Pleasanton, CA | MRI Body Array |
| Optometrics | , | Acquired by Dynasil, Mar 2005 |
| BaseHealth | , | Acquired by Genalyte, Apr 2020 |
| Advanced Infusion | , | Website down Jan 2018 - Feb 2018, Emails bouncing |
| Beta Pharma | Princeton, NJ | Small Molecules |
| Darling Therapeutics | , | Website down Jun 2023 - Feb 2024; Stealth Dec 2022 |
| Milkhaus Laboratory | , | Got out of pharma business by offloading assets to Beech Tree Labs in 2004 |
| Structure Medical | Mooresville, NC | Precision Implant Manufacturing |
| Biopredic | , | Renamed Wepredic, Mar 2022 |
| FLUIDDA | Kontich, Belgium | Functional Respiratory Imaging |
| Pharmathen | Marousi, Greece | Generics |
| Prometheus Laboratories | , | Sold by Nestle to Precision IBD Jun 2019, rebranded Prometheus Biosciences |
| Cardioxyl Therapeutics | , | Bought by BMS, Nov 2015, $300M |
| Pyramid Labs | , | Renamed Pyramid Pharma Services, Jun 2025 |
| Tetra Bio-Pharma | , | Website now Canadian Pharmacy |
| Cellpep | , | Merged with Procyon to become Ambrilia Biopharma, Jan 2006 |
| ProgenaBiome | Ventura, CA | Genetic Sequencing |
| FloDesign Sonics | , | Acquired by MilliporeSigma, Oct 2019 |
| Provention Bio | , | Acquired by Sanofi, Apr 2023, $2.9B |
| Abionic | Epalinges, Switzerland | Rapid Sepsis Diagnostic Device |
| KPL | , | Acquired by SeraCare, Aug 2013, Stock |
| New Brunswick Scientific | , | Merged into Eppendorf |
| , | Website down Jan 2026 - May 2026 | |
| Pippin Therapeutics | , | Renamed Akero Therapeutics, Jun 2018 |
| Spring Discovery | , | Renamed Spring Science |
| InGeneron | Munich, Germany | Stem cell collection and processing technology, Therapy |
| Cerner Enviza | , | Acquired by Oracle, Jun 2022; fka Kantar Health |
| Mercury Bio | Santa Fe, NM | Next-generation Biomolecular Drug Delivery Platform |
| Oakwood Labs | Oakwood Village, OH | Sterile Injectables |
| ActivaTek | , | Acquired by North Coast Medical |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Macrolide Pharmaceuticals | , | Renamed Zikani Therapeutics 2019 |
| Ausun Pharmaceutical | Zhejiang , China | APIs and Intermediates |
| Cenexi | Osny, France | Sterile Pharmaceutical Manufacturing |
| Expression Manufacturing | West Chester, OH | CDMO that specializes in cell and lentiviral vector manufacturing |
| HKG Epitherapeutics | , | Renamed EpiMedTechGlobal, Jun 2024 |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Biostorage Lab Services | , | Website down Nov 2023 - Mar 2024 |
| Innolake Biopharm | Hangzhou, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Synthon | , | |
| AMDL | , | Now Radient Pharmaceuticals |
| Sinclair Research | , | Acquired by Altasciences, Jan 2022 |
| Confluent Medical Technologies | Fremont, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Patagonia Pharmaceuticals | , | Majority of assets acquired by Timber Pharmaceuticals, 2019 |
| Cliniqa | San Marcos, CA | Lab Research Products, Biomaterials |
| Verra Therapeutics | , | 8 years preclinical, Mar 2025 |
| Somagenics | Santa Cruz, CA | RNAi technology / Diagnostics |
| Eleven Therapeutics | Cambridge, UK | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Verenium | , | Bought by BASF, Dec 2013 |
| Manifold Bio | Boston, MA | Measurement-driven drug design |
| VAXX | , | Not sure what happened to them |
| |
Waltham, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Healthpoint Biotherapeutics | , | Acquired by Smith & Nephew, Sep 2013, $782M |
| AnTolRx | , | Renamed Immunocodex, Feb 2024 |
| Drawbridge Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; under construction May 2023 - Jul 2023 |
| Irvine Pharmaceutical Services | , | Acquired by Nitto Denko Avecia, Oct 2016 |
| Diaccurate | , | Renamed Evexta Bio, Nov 2023 |
| Charnwood Molecular | , | Renamed Charmwood Discovery, Sep 2023 |
| DyNAbind | , | Shut down Apr 2025 |
| Sonus Pharma | , | Merged with Oncogenex |
| Akkadix | , | Gone 2001 |
| Proteome Systems | , | Renamed Tyrian Diagnostics, 2008 |
| International Process Solutions | San Carlos, CA | Calibration, validation, preventative maintenance, and data management services |
| SemBioSys | , | Bankrupt, Jul 2012 |
| Protein Forest | , | Bought by Cell Biosciences |
| Century Therapeutics | Branchburg, NJ | iPSC Therapy platform |
| Avotres | Cedar Knolls, NJ | Biologics for Immuno-Oncology |
| SalvaRx | , | Bought by Portage Biotech, Aug 2018 |
| AFFiRiS | Vienna, Austria | Therapeutic Vaccines |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| Noble | Orlando, FL | Auto-injector Trainers |
| , | Website down Jan 2026 - May 2026 | |
| PlateletBio | , | Website down Dec 2022 - Apr 2023; fka Platelet BioGenesis |
| BioThrust | Aachen, Germany | High Gas Transfer Bioreactor |
| , | Renamed Aurevia | |
| Labrys Biologics | , | Bought by Teva, Jun 2014 |
| Ingenus Pharmaceuticals | Orlando, FL | Generics & OTC |
| Siegfried | Irvine, CA | Contract Drug Manufacturing, APIS, Development |
| PepVax | , | Gone 2024 |
| xCella Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $7M |
| AccuRna | Tokyo, Japan | Nucleic Acid Therapeutics |
| BAP Pharma | Somerset, NJ | Clinical Supplies |
| Target Pharmaceuticals | , | Renamed Nanosmart Pharmaceuticals, Jun 2006 |
| Cohance Lifesciences | Hyderabad, India | Contract Manufacturing, ADC development |
| United Neuroscience | , | Renamed Vaxxinity |
| Madison Vaccines | , | Website gone Dec 2019 |
| Beijing Fogangren Bio-pharma | , | Website down Sep 2021 - Feb 2022 |
| EMD Serono | Billerica, MA | Small Molecules, Biologics |
| ConvaTec | Bridgewater, NJ | Wound Care, Infusion Systems, Critical Care |
| TheraSense | , | Acquired by Abbott, Jan 2004, $1.2B |
| Kalytera Therapeutics | , | Renamed Claritas, Apr 2021 |
| Mysthera Therapeutics | , | Website down Apr 2025 - Aug 2025 |
| Bayer | Mississauga, ON | Biotech / Pharma / Chemical Giant |
| GT Molecular | Fort Collins, CO | PCR Kits |
| Cocoon Bioscience | Vizcaya, Spain | Custom Biologics Development |
| Wepredic | Saint Gregorie, France | Cell Lines |
| |
London, UK | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Ergomed | Geneva, Switzerland | Clinical Research |
| Antiva Biosciences | Redwood City, CA | Antiviral therapy |
| Cullinan Therapeutics | Cambridge, MA | In-Licensing & Developing Oncology Assets for Sale |
| Nephrion | , | Closed 2006? |
| KXT bio | , | Shut down 2019 |
| ZWI Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| ReForm Biologics | , | Renamed Comera Life Sciences, Jan 2022 |
| NantHealth | El Segundo, CA | Diagnostics |
| ST Pharm | Seoul, Korea | Contract API, RNA, DNA |
| Beardsworth | , | Bought by TFS International 2013 |
| ITM Isotopen Technologien München | Garching, Germany | Targeted diagnostic and therapeutic radiopharmaceuticals and radionuclides for use in cancer treatment |
| VitriVax | Boulder, CO | Thermostabilization and Atomic Layer Deposition methods for Vaccine Formulation |
| Tavanta Therapeutics | King of Prussia, PA | Specialty Pharma |
| SGS Quay Pharma | , | |
| MetrioPharm | Zurich, Switzerland | Small Molecules |
| Rontis | Veles, North Macedonia | Generics, Contract Manufacturing |
| Mako Surgical | , | Acquired by Stryker, Sep 2013, $1.65B |
| Tokalas | , | Merged with Oncternal Therapeutics, Jun 2016 |
| Spinal Elements | Carlsbad, CA | Spinal Implants |
| Microbiology & Quality Associates | , | Part of Analytical Lab Group |
| Circuit Therapeutics | , | Website down Feb 2021 - Oct 2021 |
| OcellO | , | Acquired by Crown Bioscience, May 2021 |
| Midwest Institute for Clinical Research | Indianapolis, IN | Clinical Research |
| Aptus Clinical | , | Website down Feb 2023 - Jul 2023 |
| Natco Pharma | Kothur, India | Generics, APIs, Contract Manufacturing |
| Precision Research Institute | , | Shut down Apr 2024 |
| HistoTox Labs | , | Acquired by Inotiv, Apr 2021, $22M |
| Aurora Biopharma | , | No news 2017 - Aug 2024 |
| SonoScape Medical | Shenzhen, China | Ultrasound, Endoscopy |
| ions.bio | Planegg, Germany | Biomarkers |
| P10 BIOSCIENCES | , | Believed defunct, Never registered as MA business, had SBIR grant |
| Cenexi | Fontenay-sous-Bois, France | Sterile Pharmaceutical Manufacturing |
| Luqa Pharmaceuticals | , | Website down Apr 2021 - Sep 2021 |
| Integer | Galway, Ireland | Medical & Surgical Devices |
| VasoGen | , | Assets acquired in complex transaction by Intellipharmaceutics, Oct 2009 |
| Nensius Research | , | Website Gone |
| Dharma Therapeutics | , | Gone, 2013 |
| Medipan | Blankenfelde-Mahlow, Germany | Assays |
| Health Diagnostic Laboratory | , | Bankrupt, Jun 2015 |
| ElevateBio | Waltham, MA | Cell & Gene Therapy CDMO, Incubator |
| BMG Pharma | Milan, Italy | B2b healthcare focused on development and out-licensing of product for dermatology, oral care, osteoarthritis, and women's health |
| VITRAC Therapeutics | , | Shut down after May 2022 |
| Isotopia Molecular Imaging | Petach Tikva, Israel | Nuclear Medicine |
| Biousian Biosystems | , | Website hacked, Jan 2016; 2009 SBIR no website Dec 2019 |
| Adorial | , | Spun out of PGXIS, Feb 2015; Acquired by C4X Discovery |
| Kirwan Surgical | Marshfield, MA | Microsurgical Tools |
| THORASYS | Montréal, QC | Lung Function Measurement |
| NewLink Genetics | , | Acquired by Lumos Pharma in Reverse Merger, Mar 2020 |
| Veredus Laboratories | Singapore, Singapore | Multiplexed molecular solutions |
| Model Medicines | San Diego, CA | AI Drug Discovery |
| Generatx | , | Website down Jul 2021 - Sep 2021; not a registered CA business |
| QuiO Technologies | , | CEO Founder gone late 2021 |
| OncXerna Therapeutics | , | Website down Nov 2023 - Jul 2024 |
| Xcelthera | , | Shut down, Apr 2021 |
| ProteinLinks | , | Seem gone |
| Eutilex | Seoul, Korea | T cell and antibody therapies |
| NanoView Biosciences | , | Acquired by Unchained Labs, May 2022; Merged with Nexgen Arrays, Dec 2016 |
| Integrated Proteomics Applications | , | Acquired by Bruker, Sep 2020 |
| miRagen Therapeutics | , | Acquired Viridian Therapeutics, Oct 2020, took that name Jan 2021 |
| Aesculap Biologics | , | Website down Jan 2025 - Jul 2025 |
| Diazyme Laboratories | Poway, CA | Diagnostic Reagents |
| VeraSci | , | Acquired by WCG, Jul 2021; fka Neurocog Trials |
| Pharmexa | , | Merged into Affitech, May 2009 |
| Huonslab | Seongnam, Korea | Antibody Delivery Technology |
| Belrose Pharma | , | Website down Aug 2019 - Aug 2020; Acquired its technology from Enzon in Apr 2013 |
| CultureTrax | , | Shut Down Dec 2019 |
| MiniVax | , | Gone Jan 2016 |
| Carmell Therapeutics | , | Renamed Carmell Coporation after merger with Axolotl Biologix, Aug 2023 |
| Calyx | , | Merged with Invicro to become Perceptive, Sep 2024 |
| Lonza | Tampa, FL | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | No news Aug 2019 - Jan 2026 | |
| Vanguard Therapeutics | , | |
| Excalipoint Therapeutics | Shanghai, | |
| InBios International | Seattle, WA | Clinical Diagnostics |
| Bionas Discovery | , | Website gone Jun 2018 |
| Medicem | Kamenné Žehrovice, Czech Republic | Medical Devices for Ophthalmology & Surgery |
| China Medical Systems | Shenzhen, China | Small Molecules, Monoclonal Antibodies |
| , | Website down Oct 2025 - Feb 2026 | |
| CIS Biotech | , | Website down Jun 2023 - Dec 2023 |
| Blueprint Genetics | Espoo, Finland | Genetic tests |
| Acelity | , | Bought by 3M, Oct 2019, $6.7B |
| Altasciences | Harleysville, PA | Contract Research |
| , | Acquired by Bausch Health, Sep 2025, $63M | |
| Hexaell Biotech | Jiading, China | Cell Therapy for Liver Disease |
| CoRegen | Aspen, CO | Genetically Engineered T Reg Cells |
| Mendus | Stockholm, Sweden | Cell Therapy for Immuno-Oncology |
| Cytomed | , | Operations acquired by UCB Pharma, Feb 1999 |
| Precision Therapeutics (2) | , | Renamed Predictive Oncology, Jun 2019 |
| Neusentis | , | Formerly known as Icagen, bought by Pfizer Oct 2011 $56M, rebranded Mar 2012, renamed Pfizer Neuroscience 2016 |
| microCHIPS Inc | , | Renamed Microchips Biotech, 2014? |
| Sequoia Genetics | London, UK | Genetic research to help inform drug discovery and development |
| ProKidney | Winston-Salem, NC | Autologous Kidney Cell Therapy |
| Ecrins Therapeutics | , | Website down Feb 2022 - Jul 2022 |
| Nonin | Plymouth, MN | Noninvasive Pulse Oximetry |
| Sitero | Coral Gables, FL | Clinical Trial Solutions |
| Laboratoires Mayoly Spindler | Chatou , France | Generics |
| Lacerta Therapeutics | , | Shut down May 2024 |
| SDiversity | , | Website down Feb 2021 - Sep 2021 |
| ExSar | , | Closed 2013. Drug assets transferred to new operating entity as same location called Zywie LLC |
| Alliance Medical Products | , | Acquired by Siegfried, May 2012 |
| Tantti | , | Acquired by Repligen, Jul 2024 |
| TentaConsult Pharma & Med | Münster, Germany | Pharma Device Consultancy |
| Vectorious Medical Technologies | Tel Aviv, Israel | In-heart Microcomputer |
| GenePOC Diagnostics | , | Acquired by Meridian Bioscience, Apr 2019, $50M + $70M milestones |
| ANTEANA THERAPEUTICS | , | Short-lived, not sure was ever serious |
| NKMax America | , | Renamed NKGEN Biotech |
| SwanBio Therapeutics | , | Merged with Freeline Therapeutics to become Spur Therapeutics, Jun 2024 |
| Actome | Freiburg, Germany | Protein Quantification |
| Syzygy Biotech | , | Renamed Empirical Bioscience, Feb 2014 |
| Phanes Therapeutics | San Diego, CA | Treatments for solid tumors and eye diseases |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Worldwide Clinical Trials | Austin, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Alcinous Pharmaceuticals | , | Website down Mar 2023 - Dec 2023 |
| Techcyte | Orem, UT | Anatomic & Clinical Pathology AI Platform |
| DNA Genotek | Ottawa, ON | DNA Sampling |
| Cortera Neurotechnologies | , | Technology bought by Nia Therapeutics, Jul 2019 |
| , | Website down Dec 2025 - May 2026 | |
| BioScale | , | Renamed ProterixBio, Apr 2016 |
| Alkeus Pharmaceuticals | Cambridge, MA | Ophthalmics |
| PulmoGeniX | , | No business filings 2016-2020 |
| AllerMAbs | , | Website gone Oct 2022 |
| Molecure | Warsaw, Poland | Novel therapeutics for neoplastic and inflammatory diseases |
| Biological Dynamics | , | Shut down Jul 2024 |
| Simtra BioPharma Solutions | Bloomington, IN | Contract Fill/Finish, Lyophilization |
| FC Therapeutics | , | Renamed Juno Therapeutics, Oct 2013 |
| Axelar | , | Presumed gone; Website down Mar 2020 - Sep 2020 |
| AES Chemunex | , | Bought by bioMerieux, May 2011 |
| Cytrellis Biosystems | Woburn, MA | Medical devices for aesthetics |
| Epocal | , | Acquired by Alere, Feb 2013 |
| ChromaTan | Lower Gwynedd, PA | Single-use, column-free purification |
| Cell Medica | , | Renamed Kuur Therapeutics, Mar 2020 |
| Zapaq | , | Merged with Athenagen to become CoMentis, Aug 2006 |
| Aromarc Therapeutics | , | Website down Feb 2025 - Jul 2025 |
| Genesis Biopharma | , | Merged into Lion Biotechnologies, 2013 |
| Myriad Pharmaceuticals | , | Now Myrexis |
| BeiGene | , | Renamed BeOne Medicines, Nov 2024 |
| Senseonics | Germantown, MD | Medical Devices |
| Genetronics Biomedical | , | Renamed Inovio Biomedical |
| Evonik Industries | Lafayette, IN | API Manufacturing |
| Vevo Therapeutics | , | Renamed Tahoe Therapeutics, Apr 2025 |
| SafetyFix Medical Technologies | St. Louis, MO | Removable Screws |
| Blaze Bioscience | Seattle, WA | Real-time cancer cell visualization for surgical applications |
| Blondin Bioscience | , | Website redirecting to an Assisted Living Facility, Jan 2020 |
| GeneAssess | , | Gone |
| Grifols | Los Angeles, CA | Diagnostics, Plasma Derivatives |
| TZ Medical | Tualatin, OR | Monitoring Solutions |
| Medion Diagnostics | , | Bought by Grifols? |
| Biovectra | Charlottetown, PE | Pharmaceutical Services |
| Evalve | , | Owned by Abbot Vascular |
| Terrestrial Bio | Woburn, MA | GLP-1 patch |
| Nicolet NeuroCare | , | Acquired by Natus Medical, Jul 2012, $58M |
| Hawaii Biotech | , | Sold Assets to Merck 2011 |
| Medispect | , | Shut Down 2013 |
| Tibet Pharmaceuticals | , | Penny stock Nov 2020, no info |
| Allotrope Medical | , | Acquired by Northgate Technologies, Apr 2023 |
| EDIRNA | , | Website down Jan 2025 - Jun 2025 |
| Kine Sciences | Seongnam, Korea | Erythroid differentiation regulator 1 targeting therapies |
| Quanterix | Billerica, MA | Protein Quantification Technology |
| PortaScience | , | Acquired by DCN Dx, Jun 2021 |
| Virometix | Schlieren, Switzerland | Vaccines |
| Bio Products Laboratory | , | Merged into Kedrion, Apr 2025 |
| Chrono Therapeutics | , | Shut Down 2019 |
| Hemaquest | , | Gone by 2017, No info |
| Andromeda Biotech | , | Acquired by Hyperion, Jun 2014 |
| TruCode Gene Repair | , | Renamed Vera Therapeutics |
| Intellisis | , | Renamed KnuEdge, Jun 2016 |
| Amprion | San Diego, CA | Brain Health Diagnostics |
| Cerecor | , | Renamed Avalo Therapeutics, Aug 2021 |
| Trudell Medical | London, ON | Inhalation Devices |
| Native Antigen Company | Oxford, UK | Development and manufacture of native viral and bacterial antigens |
| OvaScience | , | Merged into Millendo therapeutics, Dec 2018 |
| Singulex | , | Shut down Jun 2019 |
| Anacura | Evergem, Belgium | Analytical |
| Scanogen | Baltimore, MD | Point-of-care diagnostics |
| Recro | , | Renamed Societal CDMO, Mar 2022; aka Recro Pharma |
| Interleukin Genetics | , | Liquidating, Jul 2017, ultimately acquired by Orig3n, Nov 2017 |
| Proteomics International | Perth, Australia | Diagnostics, Analytical Services |
| Antharis Therapeutics | San Diego, CA | Discovery and development of monoclonal antibodies and ADCs |
| Sygnature Discovery | Cambridge, MA | Drug Discovery Contract Research |
| Kyowa Hakko Kirin | La Jolla, CA | Platform Drug Discovery Technology |
| Lumicell | Waltham, MA | Cancer imaging device technology |
| AIBioTech | , | Assets auction, Aug 2017 |
| Cytyc | , | Acquired by Hologic, May 2007, $6.2B |
| Pharmaceutical Development Company | , | Website down Feb 2021 - May 2021 |
| SOLADIS | , | Acquired by Efor, 2021 |
| Bio-Stream Diagnostics | Edmonton, AB | Diagnostic Platform |
| Genoskin | Toulouse, France | ex vivo Clinical Testing |
| BSP Pharmaceuticals | Latina Scalo, Italy | Contract Development & Manufacturing |
| Nanologix | , | CEO/Sole Employee retired, Dec 2023 |
| Kartos Therapeutics | Redwood City, CA | Oral MDM2 Inhibitor |
| Monte Rosa Therapeutics | Basel , Switzerland | Small molecule cancer drugs that modulate protein degradation pathways |
| ViCapsys Life Sciences | , | Website down Feb 2024 - Jul 2024 |
| Oxonium Therapeutics | , | Website not working May 2021 - Sep 2021 |
| , | Bought by Veracyte, Mar 2021, $600M | |
| Northway Biotech | Vilnius, Lithuania | Contract research |
| Agility Life Sciences | Nottingham, UK | Formulation CDMO |
| Elektrofi | Boston, MA | Biologics Formulation |
| , | No website Aug 2023 - Mar 2026; rapatx.com emails used; Rockville MD | |
| Medfiles | Kuopio, Finland | Clinical Consulting |
| Altavant Sciences | , | Merged with Enzyvant, Dec 2022 |
| Xoc Pharmaceuticals | , | Website down Aug 2024 - Dec 2024; Business Filings late Jan 2022 - Dec 2024 |
| Sterling Pharma Solutions | Deeside, UK | Contract Development & Manufacturing - APIs |
| Twelve | , | Bought by Medtronic, Aug 2015, $458M |
| MiTeGen | Ithaca, NY | Technologies and services for crystallography, cryogenic electron microscopy |
| Aptitude Medical Systems | Goleta, CA | Aptamers |
| Mutual Pharmaceutical | , | Company apparently still exists as of 2013 according to PA business registry, but no information |
| PHYSIIO International | , | Renamed Empatica, Jun 2014 |
| , | Pivoted to compute, Dec 2025; fka Precision Therapeutics; Merged with Helomics, Jul 2018 | |
| Globavir Biosciences | , | Website down Oct 2022 - Mar 2023 |
| Cylex | , | Bought by Viracor-IBT Feb 2013 |
| Osiris Therapeutics | , | Acquired by Smith & Nephew, Apr 2019, $660M |
| Altura Medical | , | Bought by Lombard Medical Aug 2015, though it was closed Aug 2013 according to Crunchbase |
| PharmaZell | , | Merged with Novasep & Farmabios to become Axplora, Oct 2022 |
| Genuiti Therapeutics | , | |
| OncoQr | , | No news 2017 - Oct 2024 |
| Cenix Biosciences | , | Website gone Jul 2015 |
| ImmunityBio | San Diego, CA | Cellular therapy |
| Trophos | , | Acquired by Roche, Jan 2015, €120M + €350 milestones |
| TrialStat Solutions | Montreal, QC | eClinical |
| CubaseBio | Stockholm, Sweden | Spatial Biology |
| Tanox | , | Acquired by Genentech, Aug 2007, $919M |
| Charles River Laboratories | Spencerville, OH | Research Animal Models and Preclinical Research |
| KCI | , | Renamed Acelity after KCI & Lifecell acquisitions |
| JIDEI Kongming Biotech | , | No info, Aug 2022 - Jul 2024; NatBio Jun 2022 |
| ARL Bio Pharma | Oklahoma City, OK | Analytical Services |
| Transnetyx | Cordova, TN | Automated PCR Services |
| Furiex Pharmaceuticals | , | Acquired by Forest Labs, Apr 2014 |
| AmXpress | Kowloon, China | Chromatography Products & Reference Standards |
| AJ Vaccines | Copenhagen, Denmark | Vaccines |
| Morphic Therapeutic | , | Acquired by Eli Lilly, Aug 2024, $3.2B |
| Strike Bio | , | Assets auction, Aug 2017 |
| Zhongze Therapeutics | Shanghai, China | Small molecules for psychiatric and neurological disorders |
| ACTA Laboratories | , | Website down Sep 2024; CA filings late Dec 2023 |
| Substipharm | Paris, France | Generics, prescription brands, otc, food supplement development |
| EnGeneIC | North Ryde, Australia | Targeted delivery of chemotherapeutics and functional nucleic acids in cancer, micro RNA |
| Biomed Diagnostics | White City, OR | In Vitro diagnostic devices and custom laboratory tools |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Ception Therapeutics | , | Acquired by Cephalon, 2010 |
| LNC Therapeutics | , | Renamed Ysopia Bioscience, Oct 2020 |
| Igenomix | Surrey, UK | Contract genetic testing for reproductive health; covid-19 pcr |
| SSCI | , | Bought from Aptuit by AMRI, Jan 2015 |
| RIana Therapeutics | Vienna, Austria | Anti-cancer Therapies |
| Rezolute | Redwood City, CA | Biologics |
| Lyterian Therapeutics | South SF, CA | Therapeutics |
| CereSpir | , | No news 2020 - Nov 2024 |
| Harmonic Discovery | Helsinki, Finland | Kinome-targeting Therapies |
| Regel Therapeutics | Cambridge, MA | AAV gene delivery |
| vivoVerse | Austin, TX | Large Scale Screening Platform for Nematodes |
| Protagen Diagnostics | , | Acquired by Oncimmune, Mar 2019 |
| iWel | Exton, PA | Glucose Meters |
| BiOraliX | , | Website down Mar 2025 - Aug 2025 |
| MIP Diagnostics | , | Renamed MIP Discovery, Jun 2022 |
| Freudenberg Medical | Alajuela, Costa Rica | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| LIBBS Farmaceutica | , | Website is now general information on Biosimilars in Brazil |
| CRISI Medical Systems | , | Acquired by BD, Mar 2015 |
| SAGICO | Tampa, FL | Spinal Analytics & Implants |
| Mindera | Vista, CA | Non-invasive skin cancer test |
| Igenomix | Marostica, Italy | Contract genetic testing for reproductive health; covid-19 pcr |
| Vaxtrials | , | Acquired by Emmes, Oct 2023 |
| , | Acquired by GNI Group, Jun 2026 | |
| Inits Pharma Audit | Montpellier, France | Pharma Audit Consultancy |
| BrightSpec | Charlottesville, VA | Molecular Rotational Resonance Instruments & Software |
| MetaSystems Group | Altlussheim, Germany | Automated Microscopy |
| Marpē Therapeutics | , | Professor sideline |
| Access Biologicals | , | Acquired by Grifols, Jun 2022, $140M for remaining 50% it did not own |
| , | Website down Jan 2026 - May 2026; fka Exopharm | |
| T-Ray Science | , | Renamed Verisante |
| Schering-Plough | , | Acquired by Merck, Nov 2009 |
| Sensorion | Montpellier, France | Inner ear disease treatments |
| , | Acquired by Sartorius, Apr 2025 | |
| Pharmathen | Amstelveen, Netherlands | Generics |
| Advanced Cell Therapies | , | Shut down for fraud 2003, unapproved stem cell treatments |
| Absorption Systems | , | Acquired by Pharmaron, Oct 2020 |
| Procos | Cameri, Italy | Contract Manufacturing |
| Viewpoint Molecular Targeting | , | Merged with isoray to become Perspective Therapeutics, Feb 2023 |
| Serimmune | , | Acquired by Infinity Bio, Jun 2025 |
| Toragen | San Diego, CA | Treatments preventing human papillomavirus |
| TORAX Medical | , | Acquired by Ethicon, Mar 2017 |
| RemeGen | Yantai, China | Antibodies, Fusion Proteins, Bifunctional antibodies |
| Figure8 Surgical | , | Surrendered business in CA |
| Allostera | , | Closed 2011 per Mark Kaufmann, former CEO |
| BioMarck Pharmaceuticals | , | Website down Oct 2022 - Feb 2023 |
| Scientific Protein Labs | Waunakee, WI | APIs, Manufacturing |
| Exegenesis Bio | Horsham, PA | Gene Therapy |
| Stryker | Flower Mound, TX | Medical Devices |
| Osseon | , | Dissolved, assets acquired by Merit medical, Sep 2014 |
| Court Square Group | Holyoke, MA | Audit Ready Compliant Cloud platform for Life Science companies |
| REVOLUTION Medicines | Redwood City, CA | Small Molecules |
| Artificial Cell Technologies | New Haven, CT | Nanofilm-Based Artificial Cells |
| Acuity Pharmaceuticals | , | Merged with Froptix and eXegenics to become Opko Health Mar 2007 |
| Susavion Biosciences | , | Website down Jun 2024 - Dec 2024 |
| Harris Pharmaceutical | , | Website down Aug 2022 - Feb 2023 |
| Pharis Biotech | , | Website gone Sep 2022 - Feb 2023 |
| Qvin | Menlo Park, CA | menstrual Blood Analysis |
| Kailera Therapeutics | Waltham, MA | Peptides, Small Molecules |
| Brevetti CEA | Sovizzo, Italy | Inspection Systems |
| Alcami | St. Louis, MO | Small Molecule & Biologics Analytical & Formulation Development |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Maverix Biomics | , | Website down Dec 2017-Mar 2018 |
| Oculex Pharmaceuticals | , | Acquired by Allergan, Oct 2003 |
| Acrigen Biosciences | Berkeley, CA | Precision Gene Editing Systems to harness the power of CRISPR for use in human therapeutics |
| Yorlabs | Beaverton, OR | Portable Wireless Ultrasound |
| Cellbox Solutions | Cologne, Germany | Cell Transport Device |
| HitGen | Chengdu, China | DNA encoded library for drug discovery |
| Eminent Services | Frederick, MD | Drug Services |
| Medtronic | Galway, Ireland | Medical Devices |
| Heraeus Medical | Sosnowiec, Poland | Medical Devices |
| Norton Scientific | , | Website Gone, Oct 2014 |
| PharmaEngine | , | Website down Feb 2024 - Dec 2024 |
| Raspberry Scientific | Sherbrooke, QC | Lyme disease screening |
| West Pharma | Jersey Shore, PA | Pharmaceutical Supplier |
| ViroMed Laboratories | , | Acquired by LabCorp, Jun 2001 |
| AI Medical Service | Tokyo, Japan | Endoscopic AI Diagnosis |
| Cyalume Medical | , | Website down Jan 2023; Not Registered in MA, Dec 2019 - Sep 2022 |
| Neion Bio | New York, NY | Genetic Engineering Platform Using Chicken Eggs |
| NeoLight | Scottsdale, AZ | Phototherapy Beds for Jaundice |
| X-Rx | , | Shut down Jun 2020 |
| Dipexium Pharmaceuticals | , | Merged into PLx Pharma, Apr 2017 |
| Avansci Bio | , | Technology bought by Roche Diagnostics, Dec 2014 |
| Arriello | South SF, CA | Strategy & Regulatory Consulting |
| , | Acquired by eurifins, Sep 2024 | |
| KineMed | , | Site gone Oct 2017; Filed Chapter 11 Bankruptcy May 2016 |
| Impac Medical Systems | , | Acquired by Elekta, Jan 2005 |
| PolyPeptide Group | Torrance, CA | Polypeptide Manufacturing |
| Rapid Micro Biosystems | Lowell, MA | Microbial Analysis |
| CrystalsFirst | Marburg, Germany | 3d modeling technology for drug design |
| RFS Pharma | , | Merged with CoCrystal Pharma, Nov 2014 |
| Cavion | , | Acquired by Jazz Pharmaceuticals, Aug 2019, $52.5M + $260M milestones; Formed out of Merger of Tau Therapeutics & Xdynia, Aug 2014 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| SDC | Waltham, MA | Clinical Data Services, Virtual Trials |
| Novo Nordisk | Fremont, CA | Regenerative medicine and stem cell therapies |
| MILabs | Houten, Netherlands | Molecular Imaging |
| EnVivo Pharmaceuticals | , | Changed name to Forum Pharmaceuticals, Apr 2014 |
| GeneCopoeia | Rockville, MD | Lab reagents |
| Corevalve | , | Acquired by Medtronic, Feb 2009, $700M + milestones |
| Certainty Therapeutics | , | No website, Dec 2018 - May 2023 |
| Targeted Diagnostics & Therapeutics | , | Shut down |
| Ferox Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Celltex Therapeutics | Houston, TX | Stem Cell Banking |
| CPI Global | , | Website gone Jun 2020 |
| Inference | Pune, India | Clinical Trial Services |
| |
Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| SciVac Therapeutics | , | Merged with VBI Vaccines, took their name Oct 2015 |
| Charles River Laboratories | Reno, NV | Research Animal Models and Preclinical Research |
| PixelEXX Systems | , | Empty website Dec 2019, founded 2011 |
| Remedica | Limassol, Cyprus | Pharma manufacturing (300+ products) |
| CaroGen | Farmington, CT | VLV-like Immunotherapy |
| CardioLabs | , | Acquired by AliveCor, Jun 2021 |
| Cardea Bio | , | Acquired by Paragraf, May 2023; fka Nanomedical Diagnostics |
| GV20 Therapeutics | Cambridge, MA | Antibody Therapeutics |
| Seragon Biosciences | Irvine, CA | Small Molecules, Gene Therapy |
| , | Website down Oct 2025 - Feb 2026 | |
| Barrier Biosciences | , | Website down Sep 2024 - Feb 2025 |
| Targeted Cell Therapies | , | Presumed gone. Listing employees on website in 2018 who left in 2011 |
| Advanced Ocular Systems | , | Acquired by scaffolding company, Dec 2008 |
| Mediwhale | Seoul, Korea | Non-invasive retina scan-based AI software |
| Ardena | Assen, Netherlands | Enhancing Solubility via Formulation Development |
| Presidio Pharmaceuticals | , | Only person listed on website doesn't even list this job on LI profile |
| Progyny | New York, NY | IVF products |
| BioInspire Technologies | , | Website down Mar 2020 - Aug 2020 |
| Sigma-Aldrich | , | Bought by Merck KgAA, Sep 2014, $17B, now part of MilliporeSigma |
| Virobay | , | Website down Nov 2018, no longer registered with CA |
| Vesalio | Dallas, TX | Vascular occlusion devices |
| Rewrite Therapeutics | , | Acquired by Intellia Therapeutics, Feb 2022, $45M + $155M milestones |
| JPM | Omm Al-Amad, Jordan | Small Molecules & Diagnostic Manufacturing |
| LumaBridge | San Antonio, TX | Clinical Research |
| Scios | , | Bought by JnJ, Feb 2003 |
| Predictive Biology | Carlsbad, CA | Identifying genetic reasons for drug response |
| MiCo Biomed | , | Seems inactive Feb 2023 |
| Interventional Systems | Kitzbühel, Austria | Surgical Robot |
| Cadence Inc | Staunton, VA | Medical Device Contract Manufacturing |
| , | Website down Jul 2025 - Oct 2025 | |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Climedo Health | Munich, Germany | Clinical Study Software |
| Flame Biosciences | , | Acquired by Leap Therapeutics, Jan 2023 |
| Livzon Pharmaceutical | Zhuhai, China | Generics, Traditional Medicines, APIs |
| Merial | , | Acquired by Sanofi 2009, swapped to Boehringer Ingelheim Jun 2016 |
| Aptagen | Jacobus, PA | Aptamers, Peptides, Nucleic Acids |
| 37degrees | Chicago, IL | Next-generation portable 2D and 3D cell culture incubation, imaging and analysis platforms |
| VitalMedix | , | Out of Money 2010 |
| Dovetail Genomics | , | Merged with Arc Bio to become Cantata Bio, Jun 2022 |
| Bigfoot Biomedical | , | Acquired by Abbott, Sep 2023 |
| MaxWell Biosystems | Zürich, Switzerland | Next-gen Electrophysiology |
| CovalX | Woburn, MA | Protein Complex Analysis |
| Beagle Bioscience | , | No idea what they do, Nov 2018 - Dec 2024 |
| Conjugate Group | Waltham, MA | Drug Development Consulting |
| Ubichem | , | Part of Lake Chemicals & Minerals |
| The Weinberg Group | , | Acquired by ProPharma Group, Jan 2019 |
| Ascyrus Medical | , | Bought by CryoLife Medical, Sep 2020 |
| HumanZyme | , | Acquired by Proteintech, Apr 2018 |
| Nanomerics | Harrow, UK | Pharmaceutical Nanotechnology |
| Surgalign | , | Chapter 11 Bankruptcy Jun 2023; fka RTI Surgical Holdings |
| Virogin Biotech | Richmond, BC | Oncolytic Virotherapy |
| , | Acquired by Smith + Nephew, Jan 2026, $450M | |
| Tico Bio | , | Renamed Inso Biosciences |
| AGC Biologics | Heidelberg, Germany | Contract Manufacturing - Biologics |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| Trishula Therapeutics | South SF, CA | Cancer Immunotherapy |
| , | Website taken over Feb 2026 | |
| Brivant Medical Engineering | , | Bought by Lake Region Medical, Aug 2009 |
| PEPperPRINT | Heidelberg, Germany | Microarray Platform |
| MIDI Labs | , | Acquired by Biolog, Jan 2023 |
| Pascal Biosciences | , | Website down Aug 2024 - Jan 2025 |
| Insightec | Tirat Carmel, Israel | Thermal Ablation via Ultrasound |
| Purdue Pharma | Stamford, CT | Small Molecules |
| , | Crypto Pivot, Nov 2025 | |
| CranioVation | , | Shut down Jan 2022 |
| Bioengine | Shanghai, China | Serum-Free Cell Culture |
| Active Biotech | Lund, Sweden | Small Molecules, Biologics |
| Helex Bio | Hyderabad, India | Gene Editing Analysis Services |
| Botiss Biomaterials | Zossen, Germany | Dental Regeneration |
| , | Acquired by Quanterix, Jul 2025, $127M | |
| In-Depth Genomics | , | Shut down Jan 2021 |
| Prothya Biosolutions | Espoo, Finland | Services and plasma-derived medicinal products |
| Scanlan International | St. Paul, MN | Surgical Instruments |
| Neos Therapeutics | , | Merged with Aytu BioScience, Mar 2021 |
| Theragenics | Buford, GA | Medical Devices |
| Rakuten Medical | San Diego, CA | Antibody conjugates for cancer |
| Metabiomics | Carlsbad, CA | Stool test for cancer |
| ValenzaBio | , | Acquired by Acelyrin, Jan 2023 |
| , | Acquired by Anthropic, Apr 2026, $400M | |
| Attovia Therapeutics | San Carlos, CA | Proprietary biparatopic nanobody platform |
| Teleflex Medical | Morrisville, NC | Surgical and Medical Devices |
| Ascentage Pharma | Rockville, MD | Small molecule cancer therapeutics |
| CyThera | , | Merged with Novocell & BresaGen to become ViaCyte in 2004 |
| TriVirix | , | Now Nortech Life Sciences |
| Cellmid | , | Website down Jul 2021 - Dec 2021; Lyramid is drug dev arm |
| Carvolix | AIX-EN-PROVENCE, France | Minimally-Invasive Prostheses |
| SigutLabs | Prague, Czech Republic | Chemical Synthesis Services |
| Avidity NanoMedicines | , | Now Avidity Biosciences |
| Curonix | Pompano Beach, FL | Minimally invasive, wireless neurostimulation systems |
| Admedus | , | Renamed Anteris Technologies, Jun 2020 |
| SK Pharmteco | Daejon, Korea | Small Molecule Development & Manufacturing |
| Lundbeck | Deerfield, IL | Small Molecules, Specializing in psychiatric/neuro |
| Axolabs | Kulmbach, Germany | Contract Oligonucleotide Work |
| Pacific Bio-Material Management | , | Acquired by Brooks Life Sciences, Jul 2017 |
| Interpares Biomedicine | , | Acquired by Clarified Precision Medicine, Aug 2021 |
| Stealth Biosciences | , | Not registered in CA, website gone Jan 2018 |
| Amneal Pharmaceuticals | Dahej, India | Generic Small Molecules |
| , | Website down Jun 2025 - Dec 2025 | |
| Adare Pharmaceuticals | , | Renamed Adare Pharma Solutions |
| Rodeo Therapeutics | , | Acquired by Amgen, Apr 2021, $55M + $666 milestones |
| Costanoan Biotechnologies | , | Gone Sep 2016 |
| NAEJA Pharmaceuticals | , | Bankrupt, 2016, came back as NAEJA-RGM, Apr 2017 |
| Respiratory Motion | , | Website hijacked Nov 2023 - Jan 2024 |
| Cloudbyz | Bengalaru, India | Clinical Trial Management Software |
| Warden Bio | , | Acquired by Kriya Therapeutics, Jan 2022 |
| Plurinomics | , | Merged with Axiogenesis to form Ncardia, Sep 2017 |
| Celyn Therapeutics | , | No website Sep 2021 - May 2023 |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| Boston Scientific | Galway, Ireland | Medical Devices |
| Simnova Biotherapeutics | Shanghai, China | CAR-NK & CAR-T Cell Therapy |
| First Dimension Biosciences | , | Website gone Aug 2022 - Dec 2022 |
| Curie Therapeutics | , | Renamed Mariana Oncology |
| Sierra Bioresearch | , | Seems inactive, Apr 2023 |
| Aptabio Therapeutics | Yongin, Korea | Transfection Reagents |
| Molzym | Bremen, Germany | Microbial DNA extraction kits, automated extraction instruments, PCR and real time PCR assay kits, DNA-free reagents |
| Bial | Coronado, Portugal | Small Molecules, Vaccines |
| Systems Oncology | Scottsdale, AZ | AI-Assisted Cancer Drug research |
| Recipharm | Strangnas, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Magpie Pharmaceuticals | Guangzhou , China | Modernizing Traditional Chinese Medicines |
| Applied Biologics | Scottsdale, AZ | Allografts, Membrane Patches |
| , | Acquired by Demeetra, Jan 2026; Spun out from Transposagen, 2016 | |
| Comprehensive Clinical Development | , | Now part of Radiant Research |
| ProPharma Group | Washington, DC | Consulting |
| Sanofi | Bridgewater, NJ | Small Molecules, Biologics |
| MicroMed Laboratories | , | Acquired by Infinity Laboratories, Jun 2020 |
| Oncotherapy Science | Kawasaki, Japan | Small Molecule, peptides, antibody therapies, contract analytical |
| Sintetica | Mendriosi, Switzerland | Analgesics & Anesthetics |
| BioTime | , | Renamed Lineage Cell Therapeutics, Aug 2019 |
| Deva Holdings | Istanbul, Turkey | Pharmaceuticals manufacturing. over 600 products in 13 areas |
| OncoPlexDx | , | Bought by Nantomics, Oct 2016 |
| Inventiva | Daix, France | Small Molecules |
| EpitoGenesis | , | Gone 2017 |
| AlphaVax | , | No employees on LI. Not sure active |
| Laboratorio Reig Jofre | Barcelona, Spain | Pharma manufacturing (antibiotics/injectable |
| Psylo | , | Renamed Xylo, Jan 2025 |
| GentiBio | Cambridge, MA | Engineered regulatory T cells |
| Novus Diagnostics | Dublin, Ireland | POC Infectious Diagnostics |
| Osteotech | , | Acquired by Medtronic Aug 2010 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Antitope | , | Now part of Abzena |
| Optivia Biotechnology | , | Acquired by BioIVT, Jul 2018 |
| Peptilogics | Pittsburgh, PA | Peptide Therapeutics |
| AddBIO | , | Gone Oct 2023 |
| Fochon Pharma | , | Seems gone Nov 2022 |
| Ark Biosciences | Shanghai, China | Respiratory Virus Therapeutics |
| Maxwell Biosciences | Austin, TX | Antivirals |
| , | Acquired by Netri, Mar 2025; fka Hippocampus Pharma | |
| Dragonfly Sciences | , | Gone? Jan 2016 |
| Nexus Discovery Advisors | , | Website expired May 2020 - Mar 2021 |
| Almatica Pharma | Morristown, NJ | Small Molecules |
| Reneo Pharmaceuticals | , | Merged with OmKure Therapeutics, Oct 2024 |
| Corline Biomedical | Uppsala, Sweden | Heparin Aggregates |
| Cambrex | Tallinn, Estonia | Small Molecules Research, Development & Manufacturing Services |
| SteriTech | Sligo, Ireland | Process Equipment |
| ABS Pharma Projects | , | Website Gone, April-Oct 2016 |
| Heat Biologics | , | Renamed Nighthawk Biosciences, Apr 2022 |
| Aixial Group | Horsham, UK | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Neopeutics | Penang, Malaysia | Drug discovery contract research |
| Bachem | Bubendorf, Switzerland | Contract Peptides, Oligos |
| , | Renamed Cyclana Bio | |
| Cook MyoSite | Pittsburgh, PA | Cell Therapies |
| Ascentage Pharma | Guangzhou, China | Small molecule cancer therapeutics |
| |
Albany, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| CellAct Pharma | , | Tech acquired by Mundipharma, 2017 |
| iHear medical | , | Acquired by InnerScope Hearing Technologies, Nov 2021 |
| BioQuadrant | , | Marked as closed on Google, Mar 2022 |
| , | Website down Jul 2025 - Jan 2026 | |
| Inte:Ligand | Maria Enzersdorf, Austria | In silico drug discovery software |
| Cianna Medical | , | Acquired by Merit Medical, Nov 2018, $200M |
| Tornier | , | Merged into Wright Medical, Oct 2015 |
| , | Website down Dec 2025 - Apr 2026 | |
| Dauntless Pharmaceuticals | , | Website down May 2022 - Oct 2022, not filing business documents from 2020 -2022 |
| QuatRx | , | Acquired by Shionogi, 2017 |
| Celenex | , | Bought by Amicus Therapeutics, Sep 2018, $100M |
| Efranat | , | Website under construction Dec 2019 - Apr 2020 |
| Atley Pharmaceuticals | , | Assets sold off in 2011 |
| Brilliant Research | , | Website gone Dec 2018 |
| Emergent BioSolutions | Gaithersburg, MD | Biologics, Contract Manufacturing, Biodefense |
| CorticoMetrics | , | Website down Nov 2023 - Mar 2024; Residential Address Jul 2022 |
| Epygen Biotech | Dubai, UAE | Biosimilars |
| Topivert | , | Liquidating Jan 2021 |
| Septodont | Saint-Maur-des-Fosses, France | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| ResVita Bio | Berkeley, CA | Engineered Skin Probiotics |
| Eureka Therapeutics | Emeryville, CA | Antibodies |
| Pharmaron | Tianjin, China | R&D Services |
| AcuNetx | , | Bankrupt, shut down Nov 2012 |
| Microbiologics | Kalamazoo, MI | Diagnostics, Services |
| Agility Clinical | , | Acquired by Precision for Medicine, Sep 2017 |
| Oscient Pharmaceuticals | , | Bankrupt, Jul 2009 |
| Cira Discovery | , | Website copyright 2003 |
| Aegis Life | , | Website down Sep 2024 - Nov 2024; Spinout of Entos Pharmaceuticals |
| AIT Bioscience | , | Acquired by Nexelis, Jul 2020 |
| Bluejay Diagnostics | Acton, MA | POC Diagnostics |
| Bioagilytix | San Diego, CA | Bioanalytical services, immunoassays, cell-based assays |
| Transdel Pharmaceuticals | , | Bankrupt, Jun 2011 |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Tracon Pharmaceuticals | , | Winding Down, Jul 2024 |
| PDL BioPharma | , | Shut down early 2021 |
| Labcyte | , | Acquired by Beckman Coulter, Jan 2019 |
| TriVascular Technologies | , | Merged into Endologix, Feb 2016 |
| Enzyre | Njimegen, Netherlands | Bleeding Diagnostic |
| Envision Medical | , | Bought by BMS, Aug 1996 |
| Syngoi Technologies | Zamudio, Spain | Synthetic DNA Technology |
| Acuson | , | Acquired by Siemens, Sep 2000, $700M |
| Compellis Pharmaceuticals | , | Shut down before Jun 2014 |
| Amneal Pharmaceuticals | Bridgewater, NJ | Generic Small Molecules |
| Ahura Scientific | , | Acquired by Thermo Fisher |
| Axplora | Wilmington, DE | Kilo lab, Chromatography |
| ACELEROX | , | 2015 spinout from Fannin, no website Dec 2019 |
| Wockhardt | Nani Daman, India | Generics, Contract Manufacturing |
| , | Renamed Helyx Industries | |
| Aeglea BioTherapeutics | , | Renamed Spyre Therapeutics, Nov 2023 |
| Boehringer Ingelheim Vetmedica | , | Acquired by Elanco, Oct 2016, $885M |
| Eikon Therapeutics | Millbrae, CA | Single Particle Tracking |
| 3Sbio | Shenyang, China | Biologics, Small Molecules |
| VitamFero | , | Website gone Aug 2018 |
| CURE Pharmaceutical | Oxnard, CA | Formulation; 505(b)(2) |
| Origenis | Planegg, Germany | Small Molecules that penetrate BBB |
| BioPro Implants | Port Huron, MI | Joint Replacements, Implants, Surgical Devices |
| Novavita Thera | , | Acquired by Castle Creek Biosciences, Jan 2022 |
| Protomer Technologies | Pasadena, CA | Glucose-responsive Insulin |
| Arno Therapeutics | , | Dissolved Dec 2017 |
| Medtronic | North Haven, CT | Medical Devices |
| Premaitha Health | , | Changed name to YourGene Bioscience, Nov 2018 |
| Empress Therapeutics | Watertown, MA | Co-Evolved Medicines |
| CellASIC | , | Bought by Millipore, May 2012 |
| Pharmos | , | Gone |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| Cherry Biotech | Paris, France | Organoid Culture |
| Avatamed | , | Website down Apr 2025 - Sep 2025 |
| Calyx Pharma | Mumbai, India | APIs |
| Avalyn Pharmaceuticals | Cambridge, MA | Therapies for the treatment of Idiopathic Pulmonary Fibrosis |
| Adventrx Pharmaceuticals | , | Changed name to Mast Therapeutics |
| TrichoScience Innovations | , | Owned by RepliCel Life Sciences |
| NuPak Medical | , | Bought by Katena Products, Jul 2017 |
| Par Health | St. Louis, MO | Generics |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Solexa | , | Merged with Illumina 2006 |
| Syngensys | Sheffield, UK | DNA, Cell Products |
| Masy BioServices | , | Acquired by Alcami, Dec 2021; fka Masy Systems |
| Dune Medical Devices | , | Acquired by Dilon Technologies, Apr 2020 |
| Kamau Therapeutics | South SF, CA | Gene Correction Technology |
| , | Website down Jan 2026 - May 2026 | |
| ICON plc. | San Antonio, TX | Clinical Trials, Consulting |
| CellPoint | , | Acquired by Galapagos, Jun 2022, €125M + €100M milestones |
| Pfizer | Newbridge, Ireland | Solid Dosage Forms |
| Ajax Therapeutics | Cambridge, MA | Computational chemistry and structural biology |
| Altus Life Science | San Jose, CA | Diagnostics & Genetic Tests |
| Anemot Therapeutics | , | No website Dec 2019 - Aug 2021 |
| Qoolabs | Carlsbad, CA | Monoclonal Antibodies, Rapid Flow Tests, Assay Kits |
| Nuvilex | , | Changed name to PharmaCyte Biotech, Jan 2015 |
| Rommelag | Sulzbach-Laufen, Germany | Blow-fill-seal, aseptic packing systems |
| SkinMedica | , | Acquired by Allergan Dec 2012 ($350 million) |
| Inspira Pharmaceuticals | , | Website down Nov 2024 - Apr 2025 |
| PAA Laboratories | , | Acquired by GE Healthcare, Aug 2011 |
| Skyran Biologics | , | Website down Jul 2022 - Nov 2022; Closely associated with Recensa Therapeutics |
| conoGenetix Biosciences | , | Renamed selectION Therapeutics |
| Halt Medical | , | Bankrupt, Jun 2017. Bought by Acessa Health. |
| Lonza | Vacaville, CA | Small Molecules, Biologics Contract Manufacturing |
| Activoris Medizintechnik | Gemünden , Germany | Packaging |
| Sirona Biochem | Vancouver, BC | Carbohydrate-Based Drugs |
| DT MedTech | s-Hertogenbosch, Netherlands | Ankle Replacements |
| Marina Biotech | , | Renamed Adhera Therapeutics, Oct 2018 |
| Conceptus | , | Bought by Bayer Apr 2013 |
| Critical Therapeutics | , | Merged with Cornerstone Therapeutics |
| |
Langenargen , Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Zenshine Pharmaceuticals | Burlingame, CA | Small Molecules |
| Commave Therapeutics | , | |
| Abdi Ibrahim | Istanbul, Turkey | Small Molecules |
| FYR Bio | Missoula, MT | Blood-based Diagnostics |
| Angel Medical Systems | , | Renamed Angel Medical Systems, Apr 2023 |
| Mitotherix | , | No Website, Apr 2014, presume gone |
| LifeSplice Pharma | , | Website copyight 2013 in Aug 2025, No News 2020 - Aug 2025 |
| Insulete | , | Website gone, presumed inactive |
| XingImaging | New Haven, CT | Neuro Biomarkers |
| Lupeng Pharma | , | No website Jul 2021 - May 2023 |
| Applied Integrin Sciences | , | Gone |
| Hema Biologics | Louisville, KY | Bleeding Treatments |
| Analytik Jena | Jena, Germany | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Chugai Pharmabody Research | Singapore, Singapore | Antibody drug discovery |
| DT MedTech | McMinnville, TN | Ankle Replacements |
| AorTech | , | Acquired RUA Medical, Mar 2020,, took name |
| Exotect | , | Founded 2015, No longer listed on Fannin Innovation website |
| Paganini Biopharma | , | Bought by OncoResponse, Nov 2017 |
| OncoEthix | , | Acquired by Merck, Dec 2014, $375M |
| , | ||
| DNA2.0 | , | Renamed ATUM, DEC 2016 |
| Sarstedt | Nümbrecht, Germany | Lab products |
| Orna Therapeutics | Watertown, MA | oRNA, Delivery |
| Apollo Spine | , | Renamed G6 Spine |
| TFF Pharmaceuticals | , | Shut down Nov 2024 |
| BinaryBio | , | Out of business Jul 2015 |
| GEMoaB Monoclonals | , | Being acquired/relocated by consortium, Jun 2021, now part of Avancell |
| Ascenth | West Lancaster, SC | Device, Diagnostics Clinical Research |
| Quantum Diamond Technologics | Waltham, MA | Biomarker Detection |
| Primordial Genetics | , | Merged with Pelican Technology to become Primrose Bio, Sep 2023 |
| , | Website down Oct 2025 - Feb 2026 | |
| GLAdiator Bioscience | , | No info or website Feb 2021 - Aug 2021; CEO signed NatBio letter Dec 2020 and is also CEO of another company |
| Getinge | Delft, Netherlands | Medical Technology |
| Thousand Oaks Biopharmaceuticals | Nantong, China | Biologics CDMO |
| NuvOx Therapeutics | Tucson, AZ | Dodecafluoropentane (DDFP)-based oxygen therapeutics |
| Pierre Fabre | Aignan, France | Oncology, derm / cosmetics |
| , | Website down Dec 2025 - Apr 2026 | |
| Connect Biopharma | Jiangsu, China | Treatments for autoimmune diseases and inflammation |
| Pace | Green Bay, WI | Analytical Testing, CDMO |
| Mperia Therapeutics | , | Website gone Dec 2020 - Apr 2021 |
| Pacgen Life Science Corporation | , | Website redirecting to Danner Lab, Sep 2022 - Nov 2022. No info |
| Kadmon | , | Acquired by Sanofi, Sep 2021 |
| Magnis Therapeutics | , | Merged with Omnis Pharmaceuticals, Mar 2016, became Vyriad |
| Corin | Cirencester , UK | Orthopedics |
| Élancé Therapeutics | , | Bispecific Antibodies |
| Pharmavize | , | Merged with Crystallics 2016, Renamed Ardena |
| Sestina Bio | , | Acquired by Inscripta, Jan 2023 |
| Sitari Pharmaceuticals | , | Acquired by GSK, Sep 2019 |
| , | Website down Dec 2025 - Jun 2026 | |
| Nexus BioPharma | , | No news 2017-2022 |
| Ensoma | Boston, MA | in vivo Gene Editing |
| Volumetric | , | Acquired by 3D Systems, Oct 2021 |
| , | Website down Jun 2025 - Dec 2025 | |
| Protelica | , | Dissolved, Dec 2006 |
| Esperion Therapeutics (1) | , | Acquired by Pfizer early 2004 $1.3B |
| AscentGene | Gaithersburg, MD | Cell Extracts & Proteins |
| Imagion Biosystems | Melbourne, Australia | Cancer Diagnostics, Nanotech |
| Hande Sciences | Suzhou, China | Contract Research & Manufacturing, Analytical, Process Development |
| CapnoPharm | Tübingen, Germany | Aerosolization of Chemotherapy |
| Universal Biosensors | Rowville, Australia | Molecular Diagnostics & Medical Devices |
| Azbil Telstar | Barcelona, Spain | Major Equipment, Installation, Consultancy |
| Eppendorf | Namur, Belgium | Wide Range of Scientific Products |
| Diag-Nose.io | Bethlehem, PA | Chronic Rhinosinusitis diagnostic and treatment platform |
| Ferrer | Barcelona, Spain | Small molecules, diagnostics, vaccines |
| , | Website taken over Dec 2025; Website down Oct 2025 - Dec 2025; fka Tesis Labs | |
| Nimble Therapeutics | , | Acquired by AbbVie, Dec 2024, $200M |
| PCI Pharma Services | San Diego, CA | Contract Manufacturing, Services |
| Corevigilance | , | Website down Feb 2024 - Jul 2024 |
| Singleron Biotechnologies | Ann Arbor, MI | Single-Cell Sequencing, Service Lab |
| Bavarian Nordic | Kvistgard, Denmark | Vaccines |
| Caristo Diagnostics | Oxford, UK | Cardiac risk evaluation |
| TCG Lifesciences | Kolkata, India | Contract Medicinal Chemistry |
| Concord Biosciences | , | Acquired by Frontage Labs, Apr 2018 |
| BetaSense | Bochum, Germany | Alzheimer's Diagnosis |
| Vascular Magnetics | , | Website not working right, July-Oct 2014. No employees on LinkedIN |
| PACT Pharma | , | Shut down Sep 2023 |
| VST Bio | San Diego, CA | Antibodies that target novel pathways |
| ThromboGenics | , | Changed name to Oxurion, Sep 2018 |
| Meditrial | New York, NY | Clinical Services, Software |
| JN Biosciences | , | Website down Sep 2023 - Mar 2024 |
| PluriCell | , | Renamed LizarBio |
| Stelios Therapeutics | , | Acquired by LEXEO Therapeutics, Jul 2021 |
| Freudenberg Medical | Minnetonka, MN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Asthmatx | , | Bought by Boston Scientific, Sep 2010, $194M + milestones |
| HepQuant | Denver, CO | Liver Disease Diagnosis |
| Alios Biopharma | , | Acquired by J&J Nov 2014, $1.75B |
| Menten AI | Stockholm, Sweden | Generative AI for Peptide Drug Design |
| Auris Surgical Robotics | , | Renamed Auris Health, Mar 2018 |
| DuPont Pharmaceuticals | , | Bought by BMS, Oct 2001, $7.8B |
| Ergomed | Mumbai, India | Clinical Research |
| Inpharmatica | , | Acquired by Galapagos, Jul 2019 |
| Biostride | , | Website gone May 2022 - Aug 2022 |
| Leinco Technologies | St. Louis, MO | Research products, contract manufacturing |
| Akrevia Therapeutics | , | Renamed Xilio Therapeutics, Mar 2020 |
| NEC | Oslo, Norway | Proprietary machine-learning based software |
| Virion\Serion | Würzburg, Germany | ELISA, immunodiagnostics |
| Prokarium | London, UK | Oral Vaccines |
| GlioPharma | , | Website down May 2020 - Sep 2020 |
| HemCon Medical Technologies | , | Renamed Tricol Biomedical |
| Kingchem Lifesciences | Shanghai , China | APIs, Intermediates |
| RAPT Therapeutics | South SF, CA | Immune-targeted cancer therapies |
| Innovation Pathways | , | Website gone, company presumed gone 2020 |
| ZebraSci | Branchburg, NJ | Contract Manufacturing, Development - Drugs & Devices |
| Savran Technologies | Newton, MA | Non-invasive Diagnostics |
| DSK InnoSciences | Newcastle, WA | Contract Chemistry Services |
| Parallel Biosystems | Watertown, MA | Human Immune Organoids for Drug Discovery |
| Unilabs | Geneva, Switzerland | Diagnostic Lab |
| Spindle Biotech | , | Acquired by Applied DNA Sciences, Jul 2023, $1.6M |
| Lunaphore Technologies | Tolochenaz, Switzerland | Tissue Analytics for In Vitro Diagnostics |
| Asklepion Pharmaceuticals | Baltimore, MD | Pediatric, rare diseases |
| MIP Discovery | , | Renamed Tozaro, Aug 2024 |
| Cytel | Ahmedabad, India | Clinical software, statistical services |
| CryoPort Systems | Brentwood, TN | Temperature-controlled supply chain solutions |
| VivaBioCell | , | Acquired by NantCell, Jun 2015 |
| Kesios Therapeutics | , | Closed down according to investors |
| STROX Biopharmaceuticals | , | No updates since 2011 as of Feb 2021 |
| Allozymes | Singapore, Singapore | Enzyme Engineering |
| Ribomed | , | Website down Sep 2021 - Oct 2021; Annual report not filed Apr 2021 |
| Voiant Medical | Los Angeles, CA | Clinical Trial Imaging |
| US Genomics | , | Now PathoGenetix |
| Oncolix | , | Website gone Oct 2019, no employees on LI |
| Covance | , | Acquired by LabCorp, Feb 2015, $5.7B |
| TheraBionic | Ettlingen, Germany | Hepatocellular carcinoma treatment device |
| Nanovery | Newcastle upon Tyne, UK | Nucleic Acid Detection technology |
| Bioscience Vaccines | , | Gone, Apr 2016? |
| Aribex | , | Acquired by Danaher, Nov 2012 |
| Oculogica | New Richmond, WI | Non-invasive eye-tracking device |
| InterShunt | Fridley, MN | Minimally Invasive Interarterial Shunts |
| XyloCor Therapeutics | King of Prussia, PA | Gene Therapy |
| Stada | Belgrade, Serbia | Generics |
| Vacthera BioTech | , | No website Jan 2020 - Aug 2021 - seems to be no employees |
| Matrixx Initiatives | , | Website down May 2021 - Sep 2021 |
| Oceanix Biosciences | , | Changed name to NovaScreen Biosciences, Sep 2000 |
| Certego Therapeutics | , | Seems gone May 2023 |
| Endotronix | Naperville, IL | Wireless Health Monitoring |
| Belkin Vision | , | Acquired by Alcon, Jul 2024, $81M |
| Bio-Rad | Hercules, CA | Research & Diagnostic Products |
| Catalent | Bridgewater, NJ | Oral Dosage Manufacturing |
| InGen Biosciences | , | Acquired by Exonhit 2012 |
| Stasys Medical | , | Shut down Feb 2025 |
| PlastoPharma | , | Renamed Adhex Pharma, Mar 2020 |
| Serenity Bioworks | , | Website down Sep 2024 - Feb 2025 |
| Risen Pharma Tech | Suzhou, China | Small Molecules, siRNA, Combination Therapies |
| , | Website down May 2026; Acquired by Element, Oct 2021 | |
| Biosynth | Louisville, KY | Antibodies & Peptides |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Celegence | Downers Grove, IL | Global Regulatory Consulting |
| Alimetry | Auckland, New Zealand | Gastric Diagnostics |
| Transform Pharmaceuticals | , | Bought by JnJ 2005 |
| 454 Life Sciences | , | Bought by Roche, Mar 2007, $454M |
| Bionova Scientific | Fremont, CA | Full-service Biologics CDMO |
| Mecuris | , | Website down Nov 2024 - Feb 2025, marked is closed on Google |
| Accugenix | , | Bought by Charles River, Aug 2012 |
| NewLimit | South SF, CA | Epigenetic Reprogramming Therapies |
| International Point Of Care | , | Acquired by Fortis Life Sciences, Jul 2023 |
| Integer | Plano, TX | Medical & Surgical Devices |
| Bravida Medical | Geneva, IL | Wound Dressing, Surgical Lights |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| Kulira Technologies | , | Website Gone Oct 2016 |
| Velsera | Creve Coeur, MO | Implementation and interpretation of next-gen sequencing for diagnostic purposes |
| Citrine Medicine | , | Website down May 2022 - Oct 2022 |
| Novartis | Basel, Switzerland | Small Molecules, Vaccines, Biologics |
| Soletics | , | Website gone Jun 2021 |
| Atlas Chemical Industries | , | Acquired by ICI, 1972 |
| Celavie Biosciences | , | Shut down Mar 2024 |
| , | Website taken over Jun 2026 | |
| Kazia Therapeutics | Sydney, Australia | Clinical-stage oncology company with a lead program in US-based phase II trials for brain cancer |
| Cardia | , | Website down Feb 2025 - Jun 2025 |
| Protalex | , | Failed 2018, shell |
| synvitrobio | , | Renamed Tierra Biosciences, Sep 2018 |
| MakroCare | Princeton, NJ | Drug Development Partner |
| Eli Lilly | Neuilly-sur-Seine, France | Small Molecules, Biologics |
| Bluefish Pharmaceuticals | Stockholm, Sweden | Generics pharmaceutical company |
| Boston Neurosciences | , | Website down Jun 2020 |
| TeraImmune | , | Acquired by Baudax Bio, Jun 2023 |
| Bluefin Biomedicine | Beverly, MA | Cancer Treatments |
| Centivax | South SF, CA | Antiinfectives, Antivenoms |
| Scinomix | Earth City, MO | Lab Automation Products |
| Nodexus | San Jose, CA | Platform to characterize, sort, and isolate single cells from biological samples |
| IMUNON | Lawrenceville, NJ | Heat-Activated Liposomal Technology, Oncology |
| Hubot CDMO | South Bend, IN | Contract Filling |
| , | Acquired by Novacyt Group | |
| OMO Consultants | ZZ, UK | Biopharmaceutical & Medical Device Consulting |
| Helsinn | Lugano, Switzerland | Small Molecules |
| Par'Immune | , | Website down May 2020 - Feb 2021 |
| Trace Biosciences | Beaverton, OR | Imaging Agents for Neurosurgery |
| Swedish Orphan Biovitrum | Basel, Switzerland | Biologics |
| Protein Metrics | Boston, MA | Protein characterization software |
| Biological E. | Hyderabad, India | Biologics, Small Molecules |
| SUDA Pharmaceuticals | , | Renamed Arovella, Oct 2021 |
| Prosion | Köln, Germany | Mimetics of Polyproline-II-Helix |
| Calhoun Vision | , | Renamed RxSight, Feb 2017 |
| Perrigo | Dublin, Ireland | Small Molecule Generics, Consumer Healthcare |
| BioMagnetic Solutions | State College, PA | Magnetic Cell Separation |
| Palmetto Pharmaceuticals | Greenville, SC | Generis |
| EnteroBiotix | Lanarkshire, UK | Fecal microbiota transplantation |
| Oncoscope | , | Assets acquired by SpectraScience, Feb 2016 |
| Grunenthal | Quito, Ecuador | Small molecules |
| ATS Labs | , | Changed name to Accuratus Lab Services |
| Prologue Medicines | Boston, MA | Viral-Derived Biologics |
| ReGenX Biosciences | Rockville, MD | Gene Therapy, Biologics |
| Epia Neuro | Alameda, CA | Brain-computer interfaces |
| , | Business filings late Mar 202 - Feb 2026; CEO gone Jun 2024, still on website Feb 2026 | |
| Norgine | Uxbridge, UK | Specialty Pharma |
| Source BioScience | Nottingham, UK | Antibodies, sequencing, lab services |
| rEVO Biologics | , | Part of LFB, Formerly GTC Biotherapeutics |
| Consort Medical | , | Acquired by Recipharm, Apr 2020 |
| Pacific Northwest Biotechnology | , | Closed 2013, according to Washington dept of revenue |
| Cyaris | Allschwil, Switzerland | Intelligent macrocycles |
| Worldwide Clinical Trials | Durham, NC | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| NeoSome Life Sciences | Billerica, MA | Contract Research |
| , | Shut down Apr 2026 | |
| Invitrogen | , | Acquired by Thermo Fisher, Apr 2013, $13.6B |
| Abbott | Sylmar, CA | Device Manufacturing |
| Steripharma | Syracuse, NY | Antibiotic Manufacturing |
| Anaeropharma Science | , | Website down Oct 2021 - Feb 2022 |
| Transpharmation | London, UK | Preclinical in vivo CRO |
| Base Therapeutics | Shanghai, China | Gene Edited Cell Therapies |
| Belharra Therapeutics | San Diego, CA | Small molecule drugs in oncology, immuno-oncology, autoimmune and neurodegenerative diseases |
| Immunovo | , | Website down Oct 2020 - Feb 2021 |
| Biomed Lublin | , | Renamed Synthaverse, Jun 2023 |
| Carterra | Salt Lake City, UT | High-throughput Antibody & Protein Characterization |
| Leo Pharma | Dublin, Ireland | Small Molecules |
| , | Part of ICE Pharma | |
| Tulyp Medical | , | Pressure-driven perfusion system |
| Caladrius Biosciences | , | Renamed Lisata Therapeutics, Sep 2022 |
| Fresenius Kabi | Uppsala, Sweden | Contract Manufacturing |
| Northern RNA | Calgary, AB | GMP Grade Plasmid DNA |
| Fermentas | , | Acquired by Thermo Fisher, May 2010, $260M |
| iTherapeutics | , | Doubt they do anything |
| Biocat | Heidelberg, Germany | Lab reagents, chemicals, instruments, etc |
| Advanced Clinical Research | , | Acquired by Velocity Clinical, Jun 2019 |
| Cole-Parmer | Mumbai, India | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| 2 Bridge | Zoersel, Belgium | Consulting |
| LifeHealth | , | Website down Mar 2022 - May 2022; CEO actively seeking job on LI, Dec 2021 |
| Diversigen | , | Website down Nov 2024 - Apr 2025; fka CoreBiome; Acquired by OraSure, Jan 2019 |
| Fidelis Research | Sofia, Bulgaria | biospecimen collections and custom contract research services |
| Aelan Cell Therapeutics | , | Renamed Aelan Cell Technologies, Apr 2015 |
| Avivia | Nijmegen, Netherlands | Small molecule services |
| IRIDEX | Mountain View, CA | Ophthalmic lasers |
| Immusoft | Seattle, WA | Autologous B cell-conditioning |
| Neuro3 Therapeutics | Cambridge, | Small Molecules, siRNA |
| Viva Biotech | Jiaxing , China | Contract Research |
| Talphera | San Mateo, CA | Oral-Transmucosal Drug Delivery |
| Adepthera | , | Shut down 2014 |
| Allarta Life Science | Hamilton, ON | Cell Therapies & Biologics |
| Symmetry Surgical | , | Acquired by Aspen Surgical, Oct 2022 |
| Mahana Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| Frontier Medicines | South SF, CA | Drug Discovery Using Chemoproteomics Platform |
| Formycon | Martinsried, Germany | Biosimilars |
| Diaxonhit | , | Website redirecting to eurobio scientific, Nov 2019 |
| La Jolla Pharmaceutical | , | Acquired by Innoviva, Aug 2022, $149M |
| Edison Oncology | Menlo Park, CA | Biomarker-driven, small molecule, targeted drug candidates |
| Blue Endo | , | No info after 2017, address does not appear occupied, Mar 2025 |
| , | Winding down Apr 2026 | |
| EAG Laboratories | Irvine, CA | Analytical & Synthesis Services |
| Santen | Osaka, Japan | Ophthalmics |
| , | Filings late Jul 2022 - Jun 2026 | |
| Differentiated Therapeutics | Boston, MA | Targeted Protein Degradation |
| Alliqua Biomedical | , | Reverse merged with Adynxx, May 2019, took name |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Catabasis Pharmaceuticals | , | Renamed Astria Therapeutics, Sep 2021 |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| , | Pivoted to food, Feb 2026 | |
| Interpace Biosciences | Parsippany, NJ | Personalized medicine through molecular diagnostics and innovation |
| Orchard Therapeutics | Boston, MA | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Alvotech | Zurich, Switzerland | Biosimilars |
| Inceptua | Berlin, Germany | Clinical Trial Services |
| Bio-Bridge Science | , | Website Gone 2-20-14, Taken over |
| Omixon | Budapest, Hungary | Next-gen sequencing products |
| Glympse Bio | , | Merged into Sunbird Bio, Aug 2023 |
| Alpharma | , | Bought by King Pharmaceuticals, now part of Zoetis |
| Jenrin Discovery | , | Shut down according to Google 2019 |
| , | Shut down 2024 | |
| Tagomics | Cambridge, UK | Multiomic Diagnostics |
| Chipiron | Paris, France | Ultra-low magnetic field MRI |
| Mercator Therapeutics | , | Changed Name to Alvos Therapeutics |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Wiener lab | Rosario, Argentina | Reagents, Instruments, Software |
| Adept Pharma and Bioscience Excellence | Hyderabad, India | Contract pharma development |
| NEMUS Bioscience | , | Renamed Emerald Bioscience |
| 3Dispense | , | Owner/sole employee stopped working there Jan 2024; fka Repco Development Technologies |
| TenSixteenBio | , | Website down Oct 2023 - Mar 2024; believe they will eventually have drug products |
| SpinaFX Medical | Toronto, ON | Steroid Injection Device |
| Omnix Medical | Jerusalem, Israel | Antibiotics |
| Cosmo | Dublin, Ireland | Specialty pharmaceuticals |
| , | Renamed Arletta Pharma Solutions, Nov 2025 | |
| Igenomix | Torrance, CA | Contract genetic testing for reproductive health; covid-19 pcr |
| Swedish Orphan Biovitrum | Waltham, MA | Biologics |
| , | Acquired, now a copper & silver explorer in Morocco | |
| Ichnos Sciences | , | Renamed Ichnos Glenmark Innovation, Jan 2024 |
| Bloomage Biotech | Jinan, China | Hyaluronic acid |
| Medevoke | , | Acquired by MEDiSTRAVA, Jan 2024 |
| Saranas | , | Website down Feb 2025 - Jul 2025 |
| BioFilm Control | , | Website down Apr 2024 - Jul 2024 |
| Medivators | , | Acquired by Cantel Medical, Sep 2015 |
| Genixus | , | Website down Jul 2024 - Dec 2024 |
| Maponos Therapeutics | Chicago, IL | Cell Therapy |
| MFX | Stevenage, UK | Cell Manufacturing Systems |
| Healionics | Seattle, WA | Biomaterials for devices |
| NovaTarg Therapeutics | , | Acquired by Pano Therapeutics, Apr 2022 |
| Ecopharm | , | Website down Feb 2021 |
| Overland Therapeutics | Shanghai, China | Novel Therapeutics |
| Biotage | Uppsala, Sweden | Medicinal & Analytical Chemistry |
| MSD | Dublin, Ireland | Women's Health Products |
| Theonys | , | Shut down late 2022; fka Theon Therapeutics |
| LGC Biosearch Technologies | Petaluma, CA | Reagents, Probes, Oligonucleotides |
| Alchemgen | , | Gone |
| Modalis Therapeutics | Tokyo, Japan | Genome Editing Tools for Therapeutic Discovery |
| Commonwealth Biotechnologies | , | Bankrupt, merged into HedgePath Pharmaceuticals |
| Labshire | Cambridge, MA | Laboratory Consulting |
| SulfaGENIX | , | Website gone, Jan 2019 |
| Genomtec | Wrocław, Poland | Molecular Diagnostic Platform |
| Gideon Pharmaceuticals | , | Acquired by Elorac Pharmaceuticals, Apr 2016 |
| Hain Lifescience | , | Acquired by Bruker, Oct 2018 (80% stake) |
| Veracyte | South SF, CA | Cytology Diagnostics |
| , | Website taken over by compounding pharmacy, May 2026 | |
| Aska Biotech | Hennigsdorf, Germany | Contract Manufacturing Biologics |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| YolTech Therapeutics | Shanghai, China | Gene Editing Therapy |
| Chimera Therapeutics | , | Not actively doing anything Dec 2024, just asking for investments |
| Certara | Tokyo, Japan | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Hudson BioPharma | , | Website down Mar 2022 - Apr 2022 |
| Roche | Welwyn, UK | Small Molecules |
| Foldrx Pharmaceuticals | , | Bought by Pfizer, Sep 2010 |
| Addrenex | , | Bought by Shionogi subsidiary Sciele, Nov 2009, $29M |
| , | Website down Nov 2025 - Apr 2026 | |
| Symbollon | , | Gone |
| EmulTech | , | Website down Jan 2025 - Jul 2025 |
| Stabilitech | , | Renamed iosBio Pharma, Jan 2021 |
| Adrenomed | Hennigsdorf, Germany | Sepsis drug |
| CytoLogix | , | Gone, Sep 2012 |
| RxSight | Aliso Viejo, CA | Adjustable intraocular lenses |
| , | Renamed MindWalk, Sep 2025 | |
| CDx Diagnostics | Suffern, NY | Sampling & 3D Imaging for Diagnosis |
| SpherIngenics | , | Presumed gone, academics' side project, emails bouncing |
| FKD Therapies | , | New Company, no website as of Apr 2014, still none in Dec 2019 |
| Boston Scientific | Valencia, CA | Medical Devices |
| AJES Life Sciences | , | Renamed L2P Research |
| Epygen Biotech | Maharashtra, India | Biosimilars |
| Axsome Therapeutics | New York, NY | CNS treatments |
| Trigemina | , | Shut down Aug 2020 |
| VRG Therapeutics | Budapest, Hungary | Ai Drug Discovery Platform |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Revotek | , | Website down May 2023 - Sep 2023 |
| Moonwalk Biosciences | South SF, CA | Epigenetic discovery and editing platform |
| Tecomet | Wilmington, MA | Implant Components |
| Losan Pharma | Neuenburg am Rhein, Germany | CDMO Manufacturing |
| AbSorber | , | Merged with Olerup, Jan 2017 |
| |
Sunderland, UK | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| AerovectRx | , | No news since 2006, Website gone |
| Magnus Medical | Burlingame, CA | Device for Depression Treatment |
| DirectSens | Vienna, Austria | Enzyme-based biosensors for healthcare diagnostics |
| CannBioRx Life Sciences | , | Renamed 180 Life Sciences |
| Createrna Science | Shanghai, China | Small Molecules |
| Sojournix | , | Shut down Jun 2021 |
| Opticyte | Seattle, WA | Cellular Oximetry |
| Themis Bioscience | , | Acquired by Merck KgAA/MSD Jun 2020 |
| Variational AI | Vancouver, BC | Small Molecule Drug Discovery |
| Arxspan | , | Renamed SciY |
| InterX | , | Acquired by NeoTX, May 2022 |
| Sanofi | Reading, UK | Small Molecules |
| Amgen | West Greenwich, RI | Small Molecules, Biologics |
| Cytosolix | , | Residential Address Jul 2022 - Aug 2022; No info Feb 2021 - Feb 2025; Yale backed |
| Blue Earth Therapeutics | Oxford, UK | Radiopharmaceuticals |
| First Wave BioPharma | , | Renamed Entero Therapeutics |
| Blue Water Biotech | , | Renamed Onconetix, Dec 2023 |
| Ceptur Therapeutics | , | Website taken over Sep 2023 - Dec 2023 |
| ATMI - Life Sciences | , | Life Science business acquired by Pall, Feb 2014 |
| , | No website updates since 2013 as of Dec 2025 | |
| Enantia | Barcelona, Spain | R&D Process Chemistry, Solid Form Development, and Medicinal Chemistry |
| Vium | , | Acquired by Recursion Pharma, Jul 2020 |
| Santaris Pharma | , | Bought by Roche, Aug 2014 |
| Roche | Burgess Hill, UK | Diagnostics |
| Hyundai Bioscience | Seoul, Korea | Antiviral Drug Delivery |
| NxGenBio Life Sciences | , | Website down Jan 2019 - Apr 2019 |
| Tolerion | , | Website down Apr 2021 - Sep 2021 |
| , | Website down Dec 2025 - Apr 2026 | |
| Viralytics | , | Bought by Merck KGaA, Jun 2018, $394M |
| Austral Biologicals | San Ramon, CA | Research product distributor, Contract Services |
| B.R.A.H.M.S. | , | Acquired by Thermo Fisher, Sep 2009, €330M |
| Baxa | , | Acquired by Baxter, Nov 2011, $380M |
| Biointron | Nanjing, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Bayer | Mechelen, Belgium | Biotech / Pharma / Chemical Giant |
| Thryv Therapeutics | Montreal, QC | LQT Syndrome Treatment |
| Element Genomics | , | Acquired by UCB, Apr 2018, up to $30M |
| Aveva Drug Delivery Systems | , | Acquired by DifGen Pharmaceuticals, Apr 2023; Acquired by Apotex, Mar 2012 |
| VistaMed | , | |
| Syntonix Pharmaceuticals | , | Acquired by Biogen, Jan 2007 |
| FluoroFinder | Broomfield, CO | Tool for Flow Cytometry |
| RayBiotech | Peachtree Corners, GA | ELISA kits & multiplex protein detection |
| Center for Clinical Research | , | Website Gone, Company Fate Unknown |
| PolyPeptide Group | San Diego, CA | Polypeptide Manufacturing |
| Beaufort | Virginia Beach, VA | Consulting - Diagnostics, Clinical, QA, etc. |
| Tiancheng Pharmaceutical | , | Acquired by Grifols, Mar 2022, $1.27B |
| Protego Biopharma | San Diego, CA | Drug Discovery Targeting protein Folding Diseases |
| EyeD Pharma | Seraing, Belgium | Optical Drug Delivery |
| Agile EndoSurgery | , | Gone |
| Fairbanks Pharmaceuticals | , | Shut down Dec 2021 |
| Twist Bioscience | Guangzhou, China | Synthetic DNA, genes and libraries |
| Salvat | Miami, FL | Small Molecules |
| Locus Pharmaceuticals | , | Rebranded part of the business as Ansaris in 2009. Whole entity is defunct. |
| Myrexis | , | Liquidating 2013 |
| TremRx | , | No activity since 2012, not registered in MA as a business |
| Biospective | Montréal , QC | Preclinical & Clinical Research |
| Ellume | , | Website taken over by spam, marked as closed Feb 2025 |
| Liminal BioSciences | Laval, QC | Small Molecules, Biologics, Protein Technologies |
| Mednoxa | , | Website gone Jan 2020 |
| Biopraxis | , | No website no info. 1996 SBIR grant. Seems to be an umbrella group |
| , | Assets acquired by Alexion, Feb 2011 | |
| Cell BioEngines | New York, NY | Cell-based Immunotherapies |
| Grupo Biotoscana | , | Acquired by Knight Therapeutics, Nov 2019 |
| Skape Bio | Copenhagen, Denmark | GPCR Drug Discovery with AI -Designed Biologics |
| Nuvation Bio | New York, NY | Oncology Treatments |
| Numerus | Wokingham, UK | Clinical Data Analysis |
| Boston Heart Diagnostics | , | Seems like a testing lab |
| Kyowa Hakko Kirin | Tokyo, Japan | Biologics |
| Denovo Biopharma | San Diego, CA | Biomarker technology |
| Vyera Pharmaceuticals | , | Website gone Oct 2024; Chapter 11 bankruptcy, May 2023; fka Turing Pharmaceuticals; Legally named Phoenixus |
| Galderma | Dallas, TX | Dermatological Consumer Products and Drugs |
| Certerra | , | Website down Apr 2022 - Jul 2022 |
| Ergomed | Surrey, UK | Clinical Research |
| Castle Creek Pharma | , | Renamed Castle Creek Biosciences |
| Kowa Pharmaceuticals | Montgomery, AL | Small Molecules |
| MSD | Leopardstown, Ireland | Small Molecules |
| Amarin | Bridgewater, NJ | Small Molecules |
| Tessa Therapeutics | , | Shut down Jul 2023 |
| ChanTest | , | Acquired by Charles River, Oct 2014, $52M + $2M milestones |
| Nexus Genomics | , | Gone 2001 |
| , | Renamed EarliPoint Health, Oct 2025 | |
| LigaChem Biosciences | Daejeon, Korea | ADC (Antibody-Drug Conjugate), Anti-biotics, Anti-coagulants & Anti-cancer therapeutics |
| VIAL Dermatology CRO | San Francisco, CA | Computation Drug Discovery, Clinical Trial Software |
| KuDOS Pharmaceuticals | , | Acquired by AstraZeneca, Dec 2005, £120M |
| Acasti Pharma | , | Renamed Grace Therapeutics, Oct 2024 |
| Chesapeake Biological Labs | , | Now known as Cangene |
| Novamab | , | No website/taken over Jan 2024 - Jul 2024 |
| Quality Bioresources | Seguin, TX | Formulation and lyophilization services for diagnostics and medical devices |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| iKaryos Diagnostics | , | Gone |
| ANA Therapeutics | , | Acquired by NeuroBo Pharmaceuticals, Dec 2020 |
| Seismic Bio | , | Renamed Seismic Therapeutic |
| JuvoBio Pharmaceuticals | , | Shut Down 2018? |
| Anthrogenesis | , | Acquired by Celegene, Jan 2003, $45M |
| Nanome | San Diego, CA | Virtual Reality Drug Discovery |
| Alucent Biomedical | , | Website down Sep 2024 - Feb 2025 |
| SAJE Pharma | , | No news 2020 - Jan 2025; Founder gone 2023 |
| Genaissance Pharmaceuticals | , | Acquired by Clinical Data, Jun 2005 |
| Healgen Scientific | Houston, TX | Diagnostic Manufacturing |
| Liminal Sciences | , | Website down Oct 2024 - Apr 2025 |
| Chia Tai TianQing Pharmaceutical Group | Lianyungang, China | Small Molecules, Generics |
| , | Acquired by Xoma, Oct 2025 | |
| Arriva Pharmaceuticals | , | fka Alphaone Pharmaceuticals, only info is a court case from 2005 |
| Stago | Franconville, France | Diagnostics |
| Jade Therapeutics | , | Acquired by EyeGate Pharma, Mar 2016, stock |
| Norganoid | Macclesfield, UK | Organoid Technology |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Fresenius Kabi | Graz, Austria | Contract Manufacturing |
| Euticals | , | Bought by AMRI, May 2016, $358M |
| Nipro Diagnostics | , | Changed name to Trividia Health, Jan 2016 |
| Canfield Scientific | Utrecht, Netherlands | Medical Imaging, Clinical Research Services |
| Epic Neuro | , | Website down, Apr 2024 - Sep 2024; Residential Address Aug 2019 |
| MetaStat | , | Website gone May 2019; Shell Company |
| Kezar Life Sciences | South SF, CA | Therapies for autoimmune disorders |
| Solano Pharmaceuticals | , | Website gone |
| Perspectum Diagnostics | Oxford, UK | Digital Diagnostics Technologies |
| Kangstem Biotech | Seoul, Korea | Cord Blood-derived Stem Cell, Culture Media |
| Divide and Conquer | , | Website gone Mar 2024 |
| DelSite | , | Bankrupt |
| ARCA Biopharma | , | Acquired by Oruka Therapeutics, Aug 2024; Merged with Nuvelo, 2009 |
| Immunetune | , | Website down May 2023 - Dec 2023 |
| Maroon Biotech | , | Gone Sep 2010 |
| GSK | Munich, Germany | Small Molecules, Vaccines, Biologics |
| Lysosomal Therapeutics | , | Acquired by BIAL, Sep 2020, rebranded BIAL Biotech |
| Advanced Circulatory Systems | , | Acquired by Zoll, Dec 2014 |
| , | Website down Jul 2025 - Dec 2025 | |
| SQZ Biotech | , | Liquidating, Feb 2024 |
| Agilux Laboratories | , | Acquired by Charles River, Oct 2016, $64M |
| Santen | Nara, Japan | Ophthalmics |
| Radiant Research | , | Merged with Synexus, Apr 2017 |
| Amarna Therapeutics | Leiden, Netherlands | Viral Gene Delivery Platform |
| Avigen | , | Bought by Medicinova, Dec 2009, $37M |
| Siolta Therapeutics | San Carlos, CA | Gut Microbiome Modification |
| In2Bones | , | Acquired by Conmed, Jun 2022, $145M |
| Visionary Pharmaceuticals | , | Gone, May 2018 |
| Bioxodes | Gosselies, Belgium | Thrombosis Therapies |
| FutureGen Biopharmaceutical | Beijing, China | ADC, Monoclonal Antibodies |
| De Novo Pharmaceuticals | , | Gone, unknown |
| Adenios | , | Closed Jun 2014 according to NY DOS |
| Berg | , | Acquired, Jan 2023 |
| Imara | , | Acquired by Enliven Therapeutics, Oct 2022 |
| Medeor Therapeutics | South SF, CA | Cellular Immunotherapy |
| Memo Therapeutics | Schlieren, Switzerland | Antibody Discovery Technology |
| Novelogics Biotechnology | , | Website Down May 2024 - Nov 2024 |
| Singleron Biotechnologies | Woodbridge, CT | Single-Cell Sequencing, Service Lab |
| MikrobEX | , | Renamed Rebiotix |
| , | Bankrupt, Jan 2023, Assets sold off May 2023 | |
| Invenio Imaging | Santa Clara, CA | Histology, Cavity Sampling |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| miRdetect | , | Website down Jan 2022 - Jul 2022 |
| ProterixBio | , | Website down Nov 2023 - Mar 2024; LI page gone Nov 2023; fka Bioscale; fka Marked Biochips |
| NeXstar Pharmaceutical | , | Merged into Gilead, Mar 1999 |
| Cleave Biosciences | , | Rebranded as Cleave Therapeutics |
| Vivamer | , | Shut down, Jul 2015 |
| Creative Bioinformatics Consultants | , | Gone |
| Hasten Pharma | Hefei, China | Small Molecules |
| Hybridon | , | Merged with Idera Pharmaceuticals, 2004 |
| Dianthus Therapeutics | Waltham, MA | Monoclonal Antibodies |
| XenoPort | , | Acquired by Arbor Pharmaceuticals, Jul 2016, $467M |
| PTS Diagnostics | Whitestown, IN | Diagnostic test systems |
| Kairos Biologics | , | Changed name to Compass Therapeutics, Jun 2014 |
| Immortagen | , | Website down Feb 2025 - Jul 2025 |
| LuxCath | , | Allied Minds subsidiary; Website gone Jun 2019 - Oct 2019 |
| Aesthera | , | Acquired by Solta Medical, Feb 2010 |
| AlphaGen Therapeutics | Shanghai, China | Radioligand Therapies |
| IRX Therapeutics | , | Renamed Brooklyn ImmunoTherapeutics, Nov 2018 |
| Surefire Medical | , | Renamed TriSalus Life Sciences, Sep 2018 |
| Incysus Therapeutics | , | Renamed IN8bio, Aug 2020 |
| Onorach | Dundee, UK | Clinical Trial Management |
| Vertical Bio | , | Acquired by Pierre Fabre, Sep 2023 |
| AP Pharma | , | Changed name to Heron Therapeutics Sep 2013 |
| Atreca | , | Sold all antibody assets to Imunome, May 2024, $5M + $7M milestones |
| TOT Biopharm | , | Renamed BioDlink, Jun 2025 |
| Cambridge Protein Arrays | Cambridge, UK | Protein microarrays |
| BiOncotech Therapeutics | , | Renamed Highlight Therapeutics, Apr 2020 |
| , | Website down Nov 2025 - Apr 2026 | |
| Xap Therapeutics | Cambridge, UK | Delivery Platform |
| Adroit Surgical | , | Defunct |
| NuLife Sciences | , | Shell acquired for a security business |
| iTolerance | Miami, FL | Implants, Cell Therapy |
| Orion Pharma | Reading, UK | Small Molecules, Generics |
| , | Renamed Mobia Medical, Feb 2026 | |
| Isis Pharmaceuticals | , | Changed named to Ionis Pharmaceuticals, Dec 2015 |
| Exogen Biotechnology | , | Website gone, Jan 2019 |
| Thermo Fisher | Auckland, New Zealand | Molecular Biology & Biotech Lab Products |
| Salzburg Therapeutics | , | Academic, solo employee outfit |
| Vega Therapeutics | , | Being acquired by Incyte, Jun 2026, $1.25B; Part of Star Therapeutics |
| Delpharm | Saint-Remy, France | Contract Manufacturing |
| 89bio | Rehovot, Israel | Liver Treatments |
| Fusion Pharmaceuticals Inc. | Hamilton, ON | Targeted Alpha Therapeutics for chemo-resistant Cancers |
| Alte Biosciences | , | Gone, Apr 2016? |
| CeloNova BioSciences | , | Renamed Alta Biomaterials |
| Pfizer | Singapore, Singapore | Small Molecules, Biologics, Vaccines |
| Pyros Pharmaceuticals | Parsippany, NJ | Generics |
| Cerep | , | Acquired by eurofins, Dec 2012 |
| ZAP Surgical | San Carlos, CA | Non-invasive Brain Tumor Treatment |
| Veritomyx | , | Website Down May 2024 - Nov 2024 |
| QLT Inc | , | Merged with Aegerion Pharmaceuticals, Nov 2016, renamed Novelion Therapeutics |
| Eutropics Pharmaceuticals | Cambridge, MA | Cancer Diagnostics |
| Goldilocks Therapeutics | , | CEO gone Aug 2022; Website gone Oct 2022 |
| Sunovion | , | Acquired by Sumitomo, Jul 2023; fka Sepracor |
| Aera Therapeutics | Cambridge, MA | Genetic Medicine Delivery |
| DiAthegen | , | Website Gone Oct 2015 |
| Biovertis | , | Acquired by Deinove, May 2018 |
| Miravo Healthcare | , | Website down Dec 2023 - May 2024 |
| KAI Research | , | Acquired by Navitas Life Sciences |
| AlfaGene Bioscience | , | Ancient website hasn't been updated since the year the company was founded (2007) |
| Solstice Neurosciences | , | Acquired by US World Meds 2010 |
| Sublime Therapeutics | , | No website, Dec 2019 - Aug 2021 |
| Phylonix | , | Website down, Mar 2018; No business filings since 2016 |
| Skeletech | , | Acquired by MDS, Aug 2005 |
| PRC Clinical | South SF, CA | Clinical Trial Management and supporting all phases of clinical studies for pharmaceutical, biotech and regenerative medicine developers globally |
| Dimension Inx | , | Renamed Dimension Bio, 2025 |
| SK Pharmteco | King of Prussia, PA | Viral Vectors |
| Resolution Therapeutics | Edinburgh, UK | Macrophage Cell Therapy |
| , | Gone Jan 2026 | |
| Cenexi | Hérouville-Saint-Clair, France | Sterile Pharmaceutical Manufacturing |
| Harmonic Discovery | Tucson, AZ | Kinome-targeting Therapies |
| Zensun | , | Website gone Jan 2019, Chinese company |
| Multerra Bio | , | Bankrupt May 2021 |
| Procognia | , | Website Gone, Layoffs 2014 |
| NeuroGenetic Pharmaceuticals | , | Website down Oct 2022 - Nov 2022 |
| Neurovative Diagnostics | Dallas, TX | Cloud-based EEG |
| INTEGA Skin Sciences | , | Acquired by Crescita Therapeutics, Sep 2016 |
| Ximedica | Plymouth, MN | Medical Device Services |
| |
Kaunas, Lithuania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Margaux Biologics | , | No website, Mar 2015 - Aug 2021 |
| Promontory Therapeutics | New York, NY | Phosphaplatins - Small Molecule Immunotherapies |
| , | Website taken over, Jan 2026 | |
| Fresenius Kabi | Toronto, ON | Infusion Therapy |
| Inrad | Kentwood, MI | Oncology markers, biopsy products |
| Heraeus Medical | Ramos Arizpe, Mexico | Medical Devices |
| Cambrex | Wiesbaden, Germany | Small Molecules Research, Development & Manufacturing Services |
| Valencia Technologies | Valencia, CA | Neuromodulation for Bladder Dysfunction |
| Acorn Biolabs | Toronto, ON | Stem Cell Preservation |
| , | Shut down Jul 2025 | |
| X-Ceptor | , | Acquired by Exelixis, Sep 2004, $22.3M |
| Neurophth Therapeutics | Wuhan, China | Ophthalmology Gene Therapy |
| Proteintech | Manchester, UK | Research Antibodies |
| Prismic Pharmaceuticals | , | Acquired by FSD Pharma, Jun 2019 |
| Ibex Biosciences | Cumberland, MD | Biologics, Cell Therapy, Gene Therapy |
| |
Jiangsu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Resinnate Therapeutics | , | Marked as closed on Google, Nov 2019 |
| Attune Medical | , | Acquired by Haemontics, Mar 2024, $160M; fka Advanced Cooling Therapy |
| Vensun Pharmaceuticals | Yardley, PA | Generics |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| bioTHER | , | Gone |
| Aadigen | , | Renamed Aanastra |
| Biotronik | Lake Oswego, OR | Pacemakers, implantable defibrillators, stents and remote patient management. |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Biomapas | Kaunas, Lithuania | Clinical, regulatory and pharmacovigilance solution provider |
| WuXi Apptec | Tianjin, China | All types of contract work for small molecules, devices |
| Zevacor | , | Acquired by Sofie Biosciences, Sep 2017 |
| Fujifilm Diosynth | Thousand Oaks, CA | Biologics Development & Manufacturing |
| Elm Tree Medical | , | Shut down Nov 2020 |
| Charles River Laboratories | Dublin, Ireland | Research Animal Models and Preclinical Research |
| Hemagen Diagnostics | Columbia, MD | Diagnostics |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| International Biophysics | , | Renamed Movair, Nov 2021 |
| Allergan | , | Acquired by AbbVie, May 2020, $63M |
| , | Website down Jun 2025 - Dec 2025 | |
| TransTech Pharma | , | Renamed vTv Therapeutics |
| MLM Medical Labs | Mönchengladbach, Germany | Clinical Lab |
| Standard BioTools | South SF, CA | Microarrays, Sequencing, Add'l Services |
| Byonyks Medical Devices | Itasca, IL | Home-based, bloodless peritoneal dialysis machines |
| Acculysis | , | Website gone, sole employee with Agilent now |
| GenEros Biopharma | , | Website down Apr 2024 - Aug 2024 |
| Phytopharm | , | Acquired by Ixico, Sept 2013 |
| Aqueduct Critical Care | , | Gone, Apr 2019 |
| Astex Pharmaceuticals | Cambridge, UK | Fragment-Based Drug Discovery |
| Axsun | , | Acquired by Excelitas Technologies Jan 2019; Spun back out by Philips, Oct 2015; Acquired by Volcano Jan 2009 |
| Neutrolis Therapeutics | , | Website gone, May 2018; Brought back as Neutrolis Apr 2019 |
| Enlaza Therapeutics | La Jolla, CA | Covalent Biologics |
| Aldena Therapeutics | , | Merged with other Medicxi companies to become Alys Pharmaceuticals, Feb 2024 |
| Chikujee Therapeutics | , | Acquired by Investors, Website Gone, CEO gone Aug 2016 |
| Intec Pharma | , | Acquired by Decoy Biosystems via Reverse Merger, Aug 2021 |
| HeartSine | Belfast, Ireland | Automated External Defibrillators |
| Ascend Diagnostics | Manchester, UK | State-of-the-art diagnostics platforms |
| Pfizer | Madrid, Spain | Small Molecules, Biologics, Vaccines |
| BeOne Medicines | Cambridge, MA | Small Molecules, Monoclonal Antibodies |
| Lyell Immunopharma | South SF, CA | Curative cell-based immunotherapies |
| AngioSense | , | Acquired by MicroHeart, Sep 2001 |
| Inovotion | La Tronche, France | In vivo oncology efficacy and toxicity assays |
| OncoPath Genomics | , | Employees all gone, still advertising a 2014 relocation on main page as of Feb 2018 |
| , | Website down Nov 2025 - Apr 2026 | |
| Vision RT | London, UK | Surface Guided Radiation Therapy systems |
| Alvos Therapeutics | , | Bought by Arrowhead Research, Apr 2012, $23.5M stock |
| QRxPharma | , | Website hawking muscle powder, May 2020 |
| Accipiter Biosciences | Seattle, WA | Multifunctional de novo biologic therapeutics |
| BriOri Biotech | , | Website down Feb 2023 - Jul 2023 |
| , | Went bankrupt, came back as Ag company Jan 2026 | |
| ActiViews | , | Acquired by Stryker, Oct 2013, $30M |
| Zinfandel Pharmaceuticals | , | No acitivty for years to 2024; Business filings late, Jul 2024; No website Dec 2019 - May 2023, allied with Takeda, Alzheimer's study failed Jan 2018 |
| XinThera | , | Acquired by Gilead, May 2023; Residential address Aug 2021 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Accugent Laboratories | , | Website gone Sep 2017 |
| BioRay Pharmaceutical | , | Website down 2020 - 2024 |
| Veeva Systems | North Sydney, Australia | Life Science Software |
| RinuaGene Biotechnology | Suzhou, China | mRNA Therapies |
| HistoIndex | Glasgow, UK | Digital Pathology |
| Athelas | Mountain View, CA | Instant point-of-care Immune-cell monitoring |
| Eiger Biopharmaceuticals | , | Chapter 11 bankruptcy, Apr 2024, sold all assets Jul 2024 |
| , | Website down Nov 2025 - Feb 2026 | |
| , | Website under construction, Nov 2023 - Jan 2026 | |
| Lifecell | , | Acquired by KCI, 2008, $1.7B; Sold to Allergan Dec 2016, $2.9B |
| Smith and Nephew | London, UK | Sports Medicine, Trauma, Wound Care, etc. |
| Novanta | Bedford, MA | Pumps, Surgical Cameras |
| aTyr Pharma | San Diego, CA | Therapeutic Proteins |
| PROMETRIKA | Cambridge, MA | Contract Clinical Work |
| TAD Pharma | Cuxhaven, Germany | Generic Small Molecules |
| Reprogenetics | , | Acquired by CooperSurgical, Jun 2016 |
| Teva | Cincinnati, OH | Small Molecules, Biologics |
| Clarus Therapeutics | , | Website down Apr 2024 - Jun 2024; Bankrupt Sep 2022 |
| Androclus Therapeutics | , | Closed, May 2007 |
| Holostem Tarapie Avanzate | Modena, Italy | Cell & Gene Therapy |
| Compass Pathways | Cheshire, UK | Psilocybin Therapy |
| Phadia | , | Acquired by Thermo Fisher, May 2011, $3.5B |
| Freudenberg Medical | Shenzhen, China | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| WorldCare Clinical | , | Merged with MedQIA to become Voiant Clinical, Sep 2023 |
| EndoInSight | , | Website taken over Sep 2021 |
| FSC Pediatrics | , | Acquired by Flamel, merged into Avadel Pharmaceuticals Jan 2017 |
| Sysmex | Tokyo, Japan | Diagnostics |
| Akron Biotechnology | Boca Raton, FL | Sera & Reagents |
| Aerami Therapeutics | , | Shut down Jul 2024; fka Dance Biopharm |
| Hycor Biomedical | Hoofddorp, Netherlands | In-Vitro Diagnostics |
| ThinkCyte | Tokyo, Japan | Image-Activated Cell Sorting |
| Thermo Fisher | Tewksbury, MA | Medical Diagnostics, Counterfeit Detection |
| Forge Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| Avaden Biosciences | , | not registered in WA, Feb 2025; No news 2022- Feb 2025 |
| Zilia | Quebec City, QC | Device for Assessment of Biomarkers in Eye |
| Argonaut Manufacturing Services | Carlsbad, CA | Argonaut is a CMO dedicated to serving highly-innovative companies in biopharmaceuticals and molecular diagnostics. Specializing in formulation, filling, finishing and final kitting. |
| Sensors for Medicine and Science | , | Changed name to Senseonics, Oct 2012 |
| StelKast | , | Acquired by Globus Medical, Sep 2019, $24.1M + $4.3M milestones |
| Cytomedix | , | Renamed Nuo Therapeutics, Oct 2014 |
| EDAP Technomed | Vaulx-en-Velin, France | Therapeutic Ultrasound |
| Zars Pharma | , | Acquired by NuVo Research |
| TRexBio | South SF, CA | Treg mapping in human tissues |
| Velesco Pharmaceutical Services | , | Acquired by Pace Analytical, Oct 2021 |
| CASPR Biotech | , | Website down Apr 2023 - Sep 2023 |
| Tarus Therapeutics | , | Acquired by Portage Biotech, Jul 2022 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| , | Part of Genesis | |
| , | No news 2018 - Sep 2025 | |
| Biologica Technologies | , | Merged with Isto Biologics, Oct 2023; aka Advanced Biologics |
| BojiMed | Guangzhou, China | Clinical Research |
| Biogazelle | , | Acquired by CellCarta, Dec 2021 |
| Mytos | London, UK | Automated Cell Culture |
| Septodont | Kent, UK | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| Voiant Medical | Waltham, MA | Imaging cro, therapeutics area expertise, & endpoint adjudication committees |
| Medifacts | , | Merged with Radpharm became CoreLab Partners |
| Ergomed | Hoofddorp, Netherlands | Clinical Research |
| Clarassance | , | Renamed Therabron Therapeutics, Dec 2014 |
| , | Acquired by BioIVT, Aug 2024 | |
| Pharyx | , | Renamed Erbi Biosystems, Nov 2019 |
| Vagdevi InnoScience | Hyderabad, India | Chemical Research Services |
| MedMira Laboratories | Halifax, NS | Rapid Test Diagnostics |
| Surmodics | Eden Prairie, MN | Coatings for IVD & Medical Devices |
| Molecular Devices | San jose, CA | Biotechnology Lab Equipment, Machines, Servicing |
| Heraeus Medical | St. Paul, MN | Medical Devices |
| Oncology Clinical Research | , | Gone |
| Eyconis | Redwood City, CA | Novel, best-in-class therapeutics for eye diseases |
| QuanDx | San Jose, CA | Molecular Diagnostics for Leukemia Fusion Genes |
| Denizen Biologics | , | Shut down Mar 2023 |
| Kiragen Bio | Allston, MA | Multiplex gene-edited CAR-T cell therapies |
| Ockham | , | Acquired by Chiltern, Jul 2014 |
| StemCell2MAX | , | Website gone Apr 2019 |
| Peptone | London, UK | Translational Biophysics |
| Marinomed Biotech | Korneuburg, Austria | Treatments from seaweed-derived polymers |
| WindMIL Therapeutics | , | Website down Aug 2022 - Jan 2023 |
| Fosun Pharma | Lisbon, Portugal | Small molecules, diagnostics, traditional |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| NovaDel Pharma | , | Business dissolved 2014 |
| Intrepid Labs | Toronto, ON | AI and robotics to accelerate drug formulation and therapeutic development |
| Adragos Pharma | Maisons-Alfort, France | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Medsenic | , | Merged with Bone Therapeutics, Oct 2022 |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Saol Therapeutics | Dublin, Ireland | Small Molecules |
| Azanta | , | Acquired by Norgine, Mar 2020 |
| Nanogen Pharmaceutical Biotechnology | Ho Chi Minh City, Vietnam | Biosimilars |
| Norgine | Luzern, Switzerland | Specialty Pharma |
| PassPort Technologies | San Diego, CA | Transdermal Microporation Drug Delivery System |
| CanBas | Shizuoka, Japan | Small Molecules |
| MGI Pharma | , | Acquired by Eisai, Jan 2008, $3.9B |
| AskBio | Durham, NC | Cellular & Protein-Based Therapies |
| Naveris | Waltham, MA | Cancer Diagnostic |
| LivaNova | London, UK | Nerve stimulation therapy |
| BeOne Medicines | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Ecron Acunova | , | Changed name to Navitas Life Sciences, Jun 2017 |
| NuPathe | , | Bought by Teva, Jan 2014, $144M |
| , | Website down Dec 2025 - Jun 2026 | |
| ArrayGen Technologies | Pune, India | Array design, analysis |
| Ultimovacs | , | Acquired by Zelluna, Feb 2025 |
| Dance Pharmaceuticals | , | Now Dance Biopharm |
| Insamo | , | |
| NatiVita | , | Website down Aug 2023 - Apr 2024 |
| Clear Image Technology | , | Now CIT Ortho |
| BioDlink | Jiangsu, China | Biosimilars, Antibodies, Gene Therapy, Vaccines |
| CMAB Biopharma | , | Website down Dec 2021 - Jul 2022 |
| TRB Chemedica International | Geneva, Switzerland | APIs, Hyaluronic Acid Products |
| Anchiano Therapeutics | , | Merged with Chemomab, Mar 2021; fka BioCanCell; discontinued failed phase 2 gene therapy product to focus on small molecule pipeline Nov 2019 |
| CapEval Pharma | Archamps, France | Drug Development Consultant |
| Optima Neuroscience | , | Acquired by Tucker-Davis Technologies, Sep 2011 |
| Veristat | Barcelona, Spain | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Azeria Therapeutics | , | Liquidating Dec 2020 |
| Proteon Therapeutics | , | Acquired by ArTara Therapeutics, Reverse Merger, Jan 2020 |
| Hillstream BioPharma | , | Renamed Tharimmune, Sep 2023 |
| The Medicines Company | , | Acquired by Novartis, Jan 2020, $9.7B |
| KARL STORZ Endoscopy | El Segundo, CA | Endoscopy |
| Sentinext Therapeutics | , | Website Gone Mar 2018 |
| Acepix Biosciences | Union City, CA | Cell based and histo-pathology products |
| Bio2 Medical | , | Tech acquired by Mermaid Medical Grup, Aug 2018 |
| Sansure Biotech | Changsha, China | Molecular Diagnostics |
| Western States Biopharmaceuticals | , | Website Taken Over |
| , | Website down May 2025 - Oct 2025 | |
| Adverum Biotechnologies | Redwood City, CA | Adeno-Associated Virus Delivery, Gene Therapy |
| Ferring Pharmaceuticals | Zhongshan, China | Manufacturing |
| Phoundry Pharmaceuticals | , | GSK spinout, bought by Intarcia, Sep 2015 |
| PhotoMedex | , | Sold assets 2016, Website Gone, Dec 2018 |
| Crystal Laboratory | , | Acquired by ALK-Abello, Dec 2016 |
| Epigenos Biosciences | , | |
| PX' Therapeutics | , | Acquired by Promise Proteomics, Jul 2019 |
| Eterna Therapeutics | , | Renamed Ernexa Therapeutics, Mar 2025 |
| Particle Sciences | , | Acquired by Agno Pharma, Dec 2023; Acquired by Lubrizol |
| Celtrix Pharmaceuticals | , | Acquired by Insmed in reverse merger, May 2000 |
| RhinoCyte | , | Website moved to a marketing agency domain |
| Foamix Pharmaceuticals | , | Merged with Menlo Therapeutics, Mar 2020 |
| Bionamic | Lund, Sweden | Software for Antibody Drug Development |
| Xeridiem | , | Acquired by Spetcrum Plastics |
| SeaSpine | , | Merged with Orthofix Jan 2023; Acquired by Integra Life Sciences, May 2011, $89M, subsequently spun back out from Integra, Jun 2015 |
| Renovaro | , | Renamed Lunai Bioworks, Aug 2025 |
| Strativa Pharmaceuticals | , | Bought by Par Pharmaceutical, Sep 2007 |
| Banner Pharmacaps | , | Acquired by Patheon, Dec 2012, Renamed Banner Life Sciences |
| CellCarta | Montréal, QC | Clinical Research |
| Xact Medical | , | Website down Mar 2024 |
| , | Acquire by Savillex, Nov 2024 | |
| Savient Pharmaceuticals | , | Bankrupt, Oct 2013 |
| Clear Genetics | , | Being Acquired by Invitae, Nov 2019, $50M |
| TELA Bio | Malvern, PA | Bioscaffolds, meshed |
| ParaPRO | Carmel, IN | Antiparasitic therapies for infestations such as head lice and scabies |
| Mobius Imaging | , | Bought by Stryker, Oct 2019, $500M |
| Medinno Pharmaceutical Technology | Gyeonggi, Korea | Cell Therapies |
| Meditope Biosciences | , | Business filings late May 2023 - Feb 2025; no news 2018-2025 |
| Sanovel | Silivri, Turkey | Generics |
| OssiFi Therapeutics | Overland Park, KS | Tissue Scaffold with Small Molecules for Bone Growth |
| Lifebit | London, UK | Genetic Data Analysis |
| CellFE | Alameda, CA | Intracellular Delivery Platform for Gene-Editing |
| , | Website down Sep 2025 - Feb 2026 | |
| Aequita Bioworks | San Carlos, CA | Antibodies for Muscle Loss Reduction |
| Dragonfly Therapeutics | Waltham, MA | Immuno-oncology Drugs |
| E3XBio | , | Website down, not active CA business Jan 2019 |
| Pediatrix Therapeutics | Shanghai, China | Small Molecules, possibly others |
| Tentamus Pharma | Derby, UK | Pharmaceutical Testing |
| Mast Group | Amiens, France | Cell Systems, Reagents, Assays |
| Chimeron Bio | Philadelphia, PA | Cancer Immunotherapy |
| Tenomix | London, ON | Robotic Tissue Grossing |
| Adapt Pharma | , | Bought by Emergent Biosolutions, Oct 2018, $635M + $100M milestones |
| Cytheris | , | Out of business 2013 |
| CTIBIOTECH | Meyzieu, France | Tissue Sample |
| HuidaGene Therapeutics | Shanghai, China | Gene Therapy, Gene editing platform, delivery vector platform |
| Entos | , | Renamed Iambic Therapeutics, Oct 2023 |
| Pure MHC | , | Everyone has other, seemingly more important jobs |
| Fresenius Kabi | Grand Island, NY | Contract Manufacturing |
| Viome Life Sciences | Bellevue, WA | Consumer mRNA analysis |
| Symetis | , | Acquired by Boston Scientific, May 2017, $435M |
| iBridge Medical | , | Website gone Jan 2020 |
| Scil Proteins | , | Renamed NavigoProteins, Feb 2017 |
| Procertus | , | Website Gone, Apr 2016 |
| Vesalius Therapeutics | Cambridge, MA | AI drug discovery using patient cell analysis |
| , | No info 2019 - Mar 2026 | |
| GVI Clinical Development Solutions | Winnipeg, MB | Clinical Research |
| Jenken Biosciences | , | Shut down by 2014 |
| Pixium Vision | , | Liquidating, Dec 2023 |
| Diatech Pharmacogenetics | Jesi, Italy | Pharmacogenetics |
| GAMUT Therapeutics | , | Acquired by SparingVision, Apr 2021 |
| Allarity Therapeutics | Tarpon Springs, FL | Cancer Treatments with Companion Diagnostics |
| Getinge | Suzhou, China | Medical Technology |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Microbial Machines | , | Website down, execs gone Aug 2024 - Nov 2024; fka SanaRx Biotherapeutics |
| Devyser | Årsta, Sweden | Genetic Diagnostics, NGS Analysis |
| Celator Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, Jul 2016, $1.5B |
| Kiadis Pharma | , | Acquired by Sanofi, Oct 2020, $357M |
| Pfizer | Brandon, MB | Small Molecules, Biologics, Vaccines |
| Scion Biomedical | , | Website down Dec 2022 - Apr 2023 |
| Novalar | , | Licensing agreement, essentially gone |
| Izana Bioscience | , | Website taken over Dec 2021 - Jan 2022 |
| ICON plc. | Farmingdale, NY | Clinical Trials, Consulting |
| Chiroscience | , | Merged with Celltech, Jun 1999 |
| Verb Surgical | , | Acquired by J&J Dec 2019 |
| GenQual | , | Inactive, Jun 2017 |
| Procept BioRobotics | San Jose, CA | Aquablation |
| Bionavigen | , | Website hijacked with redirects, Apr 2024 - Jul 2024, may have shut down years prior |
| ImmuSmol | Bordeaux, France | Antibodies to detect small molecules |
| OncoArendi Therapeutics | , | Renamed Molecure, Apr 2022 |
| TandemAI | Cambridge, MA | AI to democratize the drug development process |
| Thomas Regulatory Resolutions | , | Shut down Jan 2024 |
| Polyvascular | Houston, TX | Transcatheter Heart Valves |
| Biologics Consulting | Alexandria, VA | Full-service regulatory and product development consulting firm for biologics, pharma and medical devices |
| Questra Clinical Research | Permatang Pauh, Malaysia | Full services for phases II-IV clinical trials |
| Endolytix | Beverly, MA | Therapeutics for Antibiotic Resistance |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| FirstSense Medical | , | Website down Jul 2022 - Dec 2022 |
| Essential Biotechnology | , | Website down Jul 2022 - Nov 2022 |
| BioMimetic | , | Acquired by Wright Medical, Mar 2013, $190M cash + $190M milestones |
| QInstruments | Jena, Germany | Lab Instruments |
| Nemis Technologies | Wädenswil, Switzerland | Luminosity-based Pathogen Detection System |
| Promedius | Seoul, Korea | Chest X-Ray to Detect Osteoporosis |
| Delivra | , | Bought by Harvest One Cannabis, Mar 2019 |
| Zylox-Tonbridge | Hangzhou, China | Neurovascular Devices |
| Primary Peptides | Vancouver, BC | Peptide Therapeutics |
| MicroSurgical Technology | Redmond, WA | Surgical Devices |
| BiomeBank | Adelaide, Australia | Curated Gut Microbiomes for Disease Treatment |
| Argentum Medical | , | Renamed Bravida Medical, Jun 2024 |
| Mathys Medical | , | Acquired by DJO, Jun 2021 |
| ACROBiosystems | Shanghai, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Vaxcell Bio | Hwasun, Korea | Cancer Immunotherapy |
| ICBio-Initiative | Bangalore, India | Full-service Contract Research Organization |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Essentia Biosystems | , | Renamed Revance Therapeutics |
| CryoLife | , | Renamed Artivion, Jan 2022 |
| Respirogen | , | Website down Mar 2025 - Aug 2025 |
| Imaging Endpoints II | Scottsdale, AZ | Imaging Services |
| HedgePath Pharmaceuticals | , | Renamed Inhibitor Therapeutics, Aug 2019 |
| ARS Pharmaceuticals | San Diego, CA | Nasal Spray Epinephrine |
| Novoresearch | , | Gone 2014 |
| Myotherix | , | Website down Mar 2021 - Jul 2021 |
| Opna Bio | Lafayette, CA | Novel oncology therapeutics |
| H3 Biomedicine | , | Founded as Eisai subsidiary |
| Tecomet | Wilmington, MA | Implant Components |
| Vésale Bioscience | , | Renamed Intelliphage, Aug 2025 |
| Integrated Laboratory Systems | , | Acquired by Inotiv, Jan 2022, $56M |
| QuantuMDx | Newcastle, UK | Diagnostics |
| NanoCell Therapeutics | Berwyn, PA | Gene Therapy |
| Sekisui Diagnostics | Maidstone , UK | Diagnostics |
| May Health | Paris, France | Ovulation Restoration Therapy |
| , | Acquired by Avania, Oct 2024 | |
| Ciclofilin Pharmaceuticals | , | Acquired by ContraVir, Jun 2016, $17M + stock |
| Metabrain Research | , | Website down Jun 2023 - Apr 2024; being changed Oct 2022 - Mar 2023 |
| Tetraphase Pharmaceuticals | , | Acquired by La Jolla Pharmaceuticals, Jul 2020, $43M |
| Avenir Pharma | , | No longer active |
| Samaritan Pharmaceuticals | , | Website Gone, Sep 2015 |
| BRH Medical | , | Listed execs works for tobacco company, Mar 2025 |
| , | Renamed PsiThera, Dec 2025 | |
| Imgenex | , | Acquired by Novus Biologicals Oct 2013 |
| CTI BioPharma | , | Acquired by Sobi, Jun 2023, $1.7B |
| Intabio | , | Acquired by SCIEX, Jan 2021 |
| Odyssey Therapeutics (1) | , | Shut down 2018 |
| Abata Therapeutics | , | Wound Down Aug 2025; fka Velox Therapeutics |
| Syntiron | St. Paul, MN | Microbial Vaccines |
| Fagron | Capelle aan den Ijssel, Netherlands | Excipients, Drug Delivery technology |
| Reliance Life Sciences | Navi Mumbai , India | Biosimilars |
| DIGNITANA | Lund, Sweden | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| QUE Oncology | , | Employees all gone, Feb 2022 |
| Amoéba | Chassieu, France | Nature-derived Biocides |
| Avion Pharmaceuticals | Alpharetta, GA | Prescription Supplements |
| Oasmia Pharmaceutical | , | Renamed Vivesto, Mar 2022 |
| Normunity | New Haven, CT | Immune Normalizer Therapies |
| Kymanox | Morrisville, NC | Life Science Consulting |
| Locate Therapeutics | , | renamed Locate Bio, Oct 2018 |
| Boston BioProducts | Milford, MA | Buffers, Reagents, Lab Products |
| Neo Scientific | Cambridge, MA | Peptide Synthesis |
| Richter BioLogics | Hamburg, Germany | Biologics development & manufacturing |
| Atherotech | , | Shut down Feb 2016 |
| JW Therapeutics | Shanghai, China | Cell Therapies |
| AusTrials | , | Now Momentum Clinical Research after Merger, Mar 2024 |
| Bright Path Pharmaceuticals | , | Renamed Bright Path Laboratories |
| Mendelian | London, UK | Rare Disease Diagnosis |
| NorthStar Medical Technologies | Beloit, WI | Medical Radioisotopes |
| Integer | Clarence, NY | Medical & Surgical Devices |
| BrainCells | , | Website gone Feb 2014 |
| Adaptimmune Therapeutics | Abingdon, UK | T Cell Cancer Therapy |
| Sarepta Therapeutics | Cambridge, MA | siRNA |
| Cellex | , | Presumed Gone |
| ScieGen Pharmaceuticals | Hauppauge, NY | Generics |
| , | Renamed NeuraNova, Jan 2026 | |
| Quantum Biosystems | , | Website down Oct 2021 - Mar 2022 |
| CGI Pharmaceuticals | , | Bought by Gilead 2010 |
| QSAM Biosciences | , | Acquired by Telix Pharmaceuticals, May 2024 |
| Accession Therapeutics | Oxford, UK | Immuno-Oncology Viral Platform |
| PFS Genomics | , | Acquired by Exact Sciences, May 2021, $30.6M |
| TRiCares | Aschheim, Germany | Heart Valve Prosthesis |
| Minovia Therapeutics | Tirat Hacarmel, Israel | Cell therapy to treat mitochondrial diseases |
| SpecificiT Pharma | , | Website gone Jun 2020 |
| Affymetrix | , | Acquired by Thermo Fisher, Apr 2016, $1.3B |
| Curve Therapeutics | Southampton, UK | Small Molecule Macrocycles |
| Triplet Therapeutics | , | Shut down Sep 2022 |
| , | Renamed Imviva Biotech, Oct 2025 | |
| Ibex Medical Analytics | Brookline, MA | Cancer Diagnostics |
| Select ImmunoGenomics | , | Acquired by GeneCentric Therapeutics, Aug 2019 |
| Lantern Pharma | Dallas, TX | Personalized cancer therapy |
| Epigentek | Farmingdale, NY | Epigenetic Assays, Related Services |
| Proteome Sciences | Surrey, UK | Proteomics |
| IVIX | , | Russian company acquired by Ovoca Bio, 2018 |
| International Process Solutions | Oceanside, CA | Calibration, validation, preventative maintenance, and data management services |
| Flamma | Chignolo di’Isola, Italy | Contract Manufacturing & Services |
| TRIANA Biomedicines | Lexington, MA | Platform to discover and develop molecular glues - E3 ubiquitin ligases |
| Puren Pharmaceuticals | Munich, Germany | Generics, OTC |
| Chime Biologics | Wuhan, China | Biologics CDMO |
| Demo Pharmaceutical Industry | Athens, Greece | Pharmaceutical manufacturing for hospital market, private market, and renal care |
| Prolific Machines | Emeryville, CA | Photomolecular platform for difficult-to-produce proteins |
| Balto Therapeutics | , | Website down Jun 2020 - Feb 2021 |
| Stablepharma | Bath, UK | Fridge Free Vaccines |
| Nivagen | Sacramento, CA | Generics, 505(b)(2) |
| Ribopro | Oss, Netherlands | mRNA Services |
| Airiver Medical | Brooklyn Park, MN | Drug Coated Balloon for Respiratory Infections |
| , | Website under construction Dec 2024 - May 2026 | |
| Sharp | Allentown, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Pfizer | Cambridge, MA | Small Molecules, Biologics |
| Innorna | Nanjing, China | Lipid Nanoparticles |
| BrainStorm Cell Therapeutics | Kiryat Aryeh, Israel | Autologous, adult stem cell therapy technology |
| JenaValve | Irvine, CA | Transcatheter aortic valve replacement system |
| GeneWEAVE Biosciences | , | Bought by Roche, Aug 2015, $190M |
| CDF Therapeutics | , | Renamed TruCode Gene Repair, Oct 2017 |
| TE Connectivity | Carlsbad, CA | Medical Devices |
| AUM LifeTech | Philadelphia, PA | Gene silencing technology |
| Textco BioSoftware | , | Website down May 2025 - Aug 2025 |
| PathMaker Neurosystems | Boston, MA | Neurostimulation therapy |
| Versanis Bio | , | Acquired by Lilly, Aug 2023, $1.9B |
| Antios Therapeutics | , | Shut down Feb 2023 |
| Gloriana Therapeutics | , | Website down Sep 2024; business filings late May 2024 |
| Pentapharm | Basel, Switzerland | APIs |
| Syntekabio | Daejeon, Korea | AI Drug Development |
| Cyclenium Pharma | Montréal, QC | Small Molecule macrocycles |
| LigoCyte Pharmaceuticals | , | Acquired by Takeda Oct 2012 |
| ImmunoGenesis | Houston, TX | Immunotherapies |
| Sotax | Aesch, Switzerland | Pharmaceutical Testing Equipment |
| Freudenberg Medical | Kaiserslautern, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Renew Medical | , | Website down Sep 2020 - Mar 2021; BioTime subsidiary |
| Imcyse | , | Liquidating, Jun 2025 |
| Tamir Biotechnology | , | Acquired by Orgenesis, Apr 2020 |
| VBS Pharmaceuticals | , | Seems to have been rolled into Vascular Biosciences |
| Rallybio | New Haven, CT | Therapeutics |
| Aptiv Solutions | , | Bought by ICON plc, May 2014 |
| Neuroptis Biotech | , | No news since 2015 as of Dec 2019. Website gone Nov 2016 |
| Cheetah Medical | , | Bought by Baxter, Oct 2019, $190M + $40 Milestones |
| Potentiometric Probes | Farmington, CT | Voltage Sensitive Dyes |
| Spiracur | , | Product bought by Acelity, Dec 2015 |
| Tigris Pharmaceuticals | , | Now Kirax |
| Magle Biopharma | Lund, Sweden | Stem Cell CDMO |
| , | Website down Dec 2025 - Jun 2026 | |
| Zounds Hearing | , | Website down Jun 2023 - Dec 2023 |
| Yapan Bio | Hyderabad, India | Biotech CDMO |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| AxoGlia Therapeutics | , | Ran out of money |
| Agenta Biotechnologies | , | Presumed gone, employees gone |
| Strongbridge Biopharma | , | Acquired by Xeris, Oct 2021, $267M; fka Cortendo |
| , | Pivoted to crypto, Apr 2026 | |
| Geron | Foster City, CA | Small Molecule |
| Bridge Laboratories | , | Gone 2013 |
| Quantificare | Metro Manila, Philippines | Medical Imaging |
| Avalign Technologies | Bala Cynwyd, PA | Orthopedics & Surgical |
| GeneNews | , | Renamed StageZero Life Sciences, Jun 2019 |
| Gestalt Diagnostics | Spokane, WA | Digital Pathology Solutions |
| Adlai Nortye | Hangzhou, China | Cancer & Metabolic Disease Treatments |
| Tianyin Pharmaceutical | , | No website Nov 2020 - Jul 2024 |
| Autotelic | , | Gone 2022 |
| Synfini | Menlo Park, CA | AI Drug Design |
| Senetek | , | Not sure what happened, no site, seem gone |
| , | Shut down June 2024 | |
| Mantle Biotech | , | Residential Address Dec 2022; Website gone Aug 2022 - Oct 2022 |
| Proteotech | , | Website gone Jul 2015 |
| Novita Healthcare | , | Renamed TALi Digital |
| DCPrime | , | Acquired by Immunicum, Dec 2020 |
| Magle Chemoswed | Malmö, Sweden | CDMO |
| RTI Biologics | , | Merged with Pioneer Surgical to become RTI Surgical |
| Acer Therapeutics | , | Acquired by Zevra Therapeutics, Nov 2023, $15M |
| DynamiCure | Waltham, MA | IO Immunotherapy |
| D2L Clinical Solutions | Bengaluru, India | Clinical Trial Management Organization |
| Teleflex Medical | Porto, Portugal | Surgical and Medical Devices |
| ACS-Biotech | Villeurbanne , France | Tissue Repair Solutions |
| Nanobac Pharmaceuticals | , | Gone |
| Enthera Pharmaceuticals | Milan, Italy | IGFBP3 Inhibitors - Monoclonal Antibody, Fusion Proteins |
| , | ||
| Spectranetics | , | Acquired by Philips, Aug 2017, $1.9B |
| VitaResc Biotech | , | Merged with CuraCyte, Jun 2002 |
| BioDetego | , | Website down Jun 2021 - Oct 2021 |
| 1st Order Pharmaceuticals | , | No website, Sold main product to Xenon Pharmaceuticals, Apr 2017 |
| , | CEO left 2020, still on website Dec 2025 | |
| Nuance Pharma | Shanghai, China | Specialty Pharmaceuticals |
| Silk Road Therapeutics | , | Website down Jul 2021 - Nov 2021 |
| InsightRX | San Francisco, CA | Dosing Model |
| Manhattan Pharmaceuticals | , | Gone |
| Versartis | , | Merged with Aravive Biologics, Oct 2018 |
| Definium Therapeutics | New York, NY | Psychedelic-Inspired Drugs |
| Telix Pharmaceuticals | Fishers, IN | Radio immunotherapy |
| Florida Biologix | , | Merged with Brammer, Mar 2016 |
| |
Bengbu, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Cirtec Medical | Santa Clara, CA | Contract Medical Devices |
| Verathon | Bothell, WA | Bronchoscope, Bladder scan, airway visualization system |
| GC Therapeutics | Cambridge, MA | Synthetic Biology to Create Therapeutic Stem Cells |
| Intellicyt | , | Acquired by Sartorius, Jun 2016, $90M |
| Teknova | Hollister, CA | Lab Supplies, Reagents |
| Graybug Vision | , | Merged with CalciMedica, Mar 2023 |
| Obalon Therapeutics | , | Merged with ReShape Lifesciences |
| Cycle Pharmaceuticals | Cambridge , UK | Repurposed drugs, generics, formulation |
| Raffles PharmaTech | Huizhou, China | Small molecule KSM/RSM/APIs. Specialties; large-scale hydrogenation, chiral, sulfur, and transition metal-containing compounds |
| Turku Bioscience | Turku, Finland | Research Services |
| Sanofi | Waterford, Ireland | Small Molecules, Biologics |
| GenEscence | , | Gone Jul 2013 |
| Endocare | , | Website down Jan 2021 - May 2021 |
| Cambridge Bioscience | Cambridge, UK | Assays, Antibodies, Reagents, Cells, etc. |
| Nasseo | , | Gone |
| Corxel Bio | Shanghai, China | Small Molecules, Nasal Spray |
| Flow Neuroscience | Malmö, Sweden | At-home, non-invasive brain stimulation headset |
| Novelos | , | Changed name to Cellectar Biosciences, Feb 2014 after seeming to close late 2013 |
| Brijjit Medical | , | Renamed BRIJ Medical, Feb 2024 |
| Solaris Biotech | Cambridge, MA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Luminate Medical | Galway, Ireland | Chemo Hair Loss Device, Peripheral Neuropathy device |
| CellarisBio | San Diego, CA | Micro-Tag cell target engagement platform |
| Novartis | Cambridge, MA | Small Molecules, Vaccines, Biologics / Diagnostics |
| Adragos Pharma | Jura, Switzerland | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Stratus Therapeutics | Watertown, MA | Off-the-shelf hematopoietic stem cell therapies |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Sentinel Oncology | Cambridge, UK | Oncology small molecules |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| Corbus Pharmaceuticals | Norwood, MA | Orphan inflammatory-fibrotic diseases |
| Synta Pharmaceuticals | , | Merged with Madrigal Therapeutics Jul 2016, planning to take name and move HQ to Philadelphia |
| ABEC | Bethlehem, PA | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Meridien Research | , | Acquired by Accel Clinical Research, Jun 2020 |
| ImmunoIVD | Nacka Strand, Sweden | In vitro diagnostic qPCR-based newborn screening kits with pre-filled reagent plates |
| AcelRx Pharmaceuticals | , | Renamed Talphera, Jan 2024 |
| Interprotein | Osaka, Japan | Highly active modulators for protein-protein interaction targets |
| , | Website down Sep 2025 - Dec 2025 | |
| Endsulin | Madison, WI | Genetic therapy for type 1 diabetes |
| IFM Therapeutics (2) | Boston, MA | Innate Immunity Therapeutics |
| InVivoScribe | San Diego, CA | Molecular Diagnostics |
| Klotho Therapeutics | , | Business not yet registered in CA Dec 2017-Oct 2024 |
| Vera Therapeutics | Brisbane, CA | Gene Editing Technology |
| Light Sciences Oncology | , | Shut down late 2020 |
| Microbiology Research Associates | , | Acquired by private equity, combined into Analytical Lab Group |
| WaVe Life Sciences | Cambridge, MA | Stereopure oligonucleotides |
| Kemwell Biopharma | , | Bought by Recipharm, Apr 2016, $205M |
| Phosphorex | Hopkinton, MA | Nanospheres for drug delivery |
| Abbott | Hoofddorp, Netherlands | Drug-Eluting Stents |
| BN Products and Services | , | Website down Jan 2023 - Jul 2023 |
| Ultragenyx Pharmaceutical | Brisbane, CA | Small Molecules, Biologics |
| Halo Pharma | , | Acquired by Noramco, Nov 2023; Acquired by Cambrex, Sep 2018, $425M |
| Oncology Venture | , | Renamed Allarity Therapeutics |
| 510 Kardiac Devices | , | Acquired by Keystone Heart, Jun 2020 |
| Valentis | , | Merged with Urigen Pharmaceuticals, Jul 2007 |
| ApcinteX | , | Centessa Company |
| Roche | Tucson, AZ | Diagnostics |
| ImmuMetrix | , | Bought by CareDx Jun 2014 |
| Solvay | , | Bought by Abbott 2010 |
| SpringWorks Therapeutics | Durham, NC | Small Molecules |
| Vical | , | Reverse Merged with Brickell Biotech, Jun 2019 |
| Corhythm | , | Website down Apr 2023 - Sep 2023 |
| Sandoz | Basel, Switzerland | Generics, Biosimilars |
| LucasPye Bio | , | Website gone Jun 2023 - Sep 2023 |
| Meissner | Castlebar, Ireland | Lab Systems |
| Amphastar Pharmaceuticals | Rancho Cucamonga, CA | Generic Small Molecules |
| ApopTrol | , | Ridiculous website as of Nov 2019 |
| BioTeam | Middleton, MA | Scientific IT consulting |
| Noah Medical | San Carlos, CA | Surgical Imaging |
| Aradigm | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Viatris (2) | Canonsburg, PA | Small Molecules, Generics |
| Sprout Pharmaceuticals | Raleigh, NC | Treatment for Hypoactive Sexual Desire Disorder |
| CYTOO Cell Architects | , | |
| Atom Bioscience | , | Renamed Atom Therapeutics, Feb 2025 |
| DiCE Molecules | , | Renamed Dice Therapeutics |
| Anchor Diagnostics | Hamburg, Germany | Diagnostics |
| Trovis Pharmaceuticals | , | Closed Jul 2011 |
| , | being Acquired by Chugai, Oct 2025 | |
| Esperance Pharmaceuticals | , | Shut down late 2023; Technology sold to A28 Therapeutics, 2022 |
| Karma Biotechnologies | , | Website gone Apr 2025; business filings late Aug 2024 |
| Nano Oncology | , | Gone |
| PathAI | Boston, MA | AI Powered Pathology |
| Agilent | Santa Clara, CA | High-Throughput Screening Equipment, Imaging instruments |
| SK Pharmteco | Dublin, Ireland | Small Molecule Development & Manufacturing |
| |
Jiangsu, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| a:head bio | Vienna, Austria | 3d tissue cultures for modeling brain disorders with the goal of developing novel cns therapeutics |
| , | Website down Jun 2025 - Dec 2025 | |
| ChromoCell | , | Renamed Channel Therapeutics, Nov 2024 |
| Omixon | Boston, MA | Next-gen sequencing products |
| ACI Clinical | , | Acquired by WCG, Mar 2018 |
| Vitalunga | , | No info Jun 2022 - Jul 2025 |
| Furtim Therapeutics | , | Shut down Dec 2019 |
| Ergomed | Zagreb, Croatia | Clinical Research |
| Farapulse | , | Acquired by Boston Scientific, Jun 2021 |
| KBI Biopharma | Plan-les-Ouates, Switzerland | Contract Development & Manufacturing |
| Farcast Biosciences | , | Website down Apr 2020 - Sep 2020; fka Mitra Biotech, Mitra RXDX |
| Charles River Laboratories | Hollister, CA | Research Animal Models and Preclinical Research |
| Synergys Biotherapeutics | , | Website down Mar 2023 - Dec 2023 |
| Novira Therapeutics | , | Bought by J&J, Nov 2015 |
| Sancilio | , | Now Micelle BioPharma |
| Laragen | , | Acquired by Transnetyx, Aug 2023 |
| pHion Therapeutics | , | Winding down Mar 2025 |
| Biotium | Fremont, CA | Fluorescent Reagents |
| eGenesis | Cambridge, MA | CRISPR for xenotransplantation |
| , | Renamed Transcend, Feb 2022 | |
| Marlex Pharmaceuticals | New Castle, DE | Generics |
| Viant Medical | Grand Rapids, MI | Contract Medical Devices |
| Sibylla Biotech | Bresso, Italy | Small Molecule Protein Degraders |
| G&L Scientifc | Marlow, UK | QARA Consulting |
| Rouken Bio | Motherwell , UK | Discovery services. Primarily in vitro systems which model in vivo interactions, pathways and effector functions. |
| InSphero | Schlieren, Switzerland | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Sannova Analytical | Somerset, NJ | Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization |
| AriBio | Gyeonggi, Korea | Neurodegenerative Therapies |
| Orion | Cambridge, UK | Drugs, Diagnostics, Veterinary medicine, etc. |
| West Pharma | Exton, PA | Pharmaceutical Supplier |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| PnuVax | , | No news 2017 - Aug 2024 |
| Immuto Scientific | Madison, WI | Protein Structure Resolution |
| ThermaGenix | , | Technically exists Feb 2024, no updates since 2018 |
| Unicus Pharmaceuticals | Taunton, MA | Contract R&D services; Topical and Oral Semisolids, Solutions & Suspensions; Drug Delivery |
| Good Therapeutics | , | Acquired by Roche, $250M, renamed Bonum Therapeutics |
| Nucleix | Rehovot, Israel | Cancer Diagnostic |
| Genhelix | , | Acquired by mAbxience, Jun 2014 |
| Trek Therapeutics | , | Shut down Sep 2019 |
| Halcygen Pharmaceuticals | , | Renamed Mayne Pharma, Nov 2010 |
| Lys Therapeutics | Caen, France | BBB-crossing Monoclonal Antibody |
| , | Website down Oct 2025 - Feb 2026 | |
| BioMAS | , | Ceased operating, Jul 2016 |
| Aviragen Therapeutics | , | Acquired by reverse merger by Vaxart, Jan 2018; fka Biota Pharmaceuticals |
| Dornier MedTech | Kennesaw, GA | Urology Devices |
| DanPET | , | One guy, Feb 2024 |
| Capsigen | Vancouver, WA | AAV Vectors |
| OriCell Therapeutics | Shanghai, China | Tumor Immunotherapy, Bispecific Antibodies, CAR T |
| Serentrix | , | Seems gone Apr 2022 |
| Tissue Therapies | , | Rebranded as Factor Therapeutics, Jan 2016 |
| Genactis | Cologne, Germany | Pharmaceutical Consulting |
| Ralexar Therapeutics | , | Website down Jul 2021 - Dec 2021; co-located with Onspira Therapeutics |
| LIPAC Oncology | Menlo Park, CA | Intravesical delivery |
| Musculoskeletal Clinical Regulatory Advisers | New York, NY | Clinical Research Consulting |
| Sterling Medical Devices | , | Renamed Vantage Medtech |
| BioStable | , | Acquired by Corcym, Apr 2023 |
| Genesis Pharmaceuticals | , | Website down Jul 2022 - Oct 2022 |
| Boston Scientific | Cork, Ireland | Medical Devices |
| NewGen Surgical | San Rafael, CA | Medical devices & surgical products |
| Pediapharm | , | Renamed Medexus Pharmaceuticals, Dec 2018 |
| , | ||
| Icagen (1) | , | Acquired by Pfizer Oct 2011, Renamed Neusentis Mar 2012, Icagen name and assets acquired by XRPro Sciences Jul 2015 |
| Thunderbolt Pharma | , | Assets acquired by Aurinia, Aug 2021, $7M |
| Ohr Pharmaceuticals | , | Acquired by NeuBase Therapeutics via Reverse Merger, Jul 2019 |
| Cassiopea | , | Absorbed into Cosmo Pharmaceuticals, Dec 2021 |
| MilliporeSigma | Sheboygan Falls, WI | Small Molecules |
| , | Renamed BTgen Bio, May 2026 | |
| Nucleo Life Sciences | , | Acquired by CoreRx, May 2021 |
| Harmonic Discovery | New York, NY | Kinome-targeting Therapies |
| Inanovate | Sioux Falls, SD | Multiplexed protein quantification platform which |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Rapamycin Holdings | , | Renamed Emtora Biosciences, Feb 2019 |
| FreeThink Technologies | Branford, CT | Stability (ASAP) software and analytical services |
| Vaxon Biotech | , | Website blocking everyone, Apr 2022, down May 2022 - Dec 2022 |
| Valar Labs | Palo Alto, CA | AI Tumor Analysis |
| Autocam Medical | Suzhou, China | Precision-Machined Medical Devices, Implants |
| Augmedics | Arlington Heights, IL | Augmented Reality Surgical Guidance System |
| AcroImmune | , | Merged with OncoC4, Sep 2024 |
| Intarcia Therapeutics | , | Acquired by i2o Therapeutics, Aug 2023 |
| CureDM | , | Acquired by Boston Scientific, Feb 2018 |
| Kapa Biosystems | , | Bought by Roche, Aug 2015 |
| SetPoint Medical | Valencia, CA | Bioelectric medicine |
| , | Acquired by Lonza, Apr 2017 | |
| Drug Development Solutions | , | Acquired by Alliance Pharma, Jul 2022 |
| Impulse Dynamics | Pearl River, NY | Implantable Heart Failure Devices |
| Bionostics | , | Bought by Techne, Jun 2013 $104M |
| Emcure Pharmaceuticals | Pune, India | APIs, Formulations |
| Synaptic Pharmaceuticals | , | Acquired by Lundbeck, Nov 2002 |
| Apollomics | Xiaoshan, China | Cancer medicines |
| Atraverse Medical | Cardiff, CA | Transeptal access technologies |
| Cipla | Mumbai, India | Generics, APIs, Formulation |
| Sollievo Pharmaceuticals | , | Shut down Jan 2025 |
| Jerome Stevens Pharmaceuticals | Bohemia, NY | Tablet, Capsules Manufacturer |
| Soligenix | Princeton, NJ | Lipoprotein Delivery, Small Molecules |
| GenoFAB | , | Renamed GenoCAB, Jul 2025 |
| Aeolus Pharmaceuticals | , | Liquidated Mar 2018 |
| OptiNose | , | Acquired by Paratek, May 2025, $330M |
| Medica Corp | Bedford, MA | In-vitro diagnostic analyzers |
| ClinActis | Singapore, Singapore | Clinical Research - Asia |
| Fujifilm Diosynth | College Station, TX | Biologics Development & Manufacturing |
| Novocure | Baar, Switzerland | Tumor Treating Fields |
| MedGene | , | Changed name to MedGene Bioscience, Jun 2000, changed again to AnGes MG Oct 2001 |
| Neox Clinical Research | , | Acquired by Emmes, Dec 2020 |
| Xeris Biopharma | Chicago, IL | Injectables |
| DNX Biopharmaceuticals | , | Supposedly doing biosimilars, but no location after 8 years |
| Montai Health | , | Renamed Montai Therapeutics, Apr 2024 |
| Riboxx | Dresden, Germany | RNA Products |
| Warner Chilcott | , | Acquired by Actavis, Oct 2013 |
| AngioScore | , | Acquired by Spectranetics, May 2014, $230M+ |
| Arctoris | Oxford, UK | Robotic Laboratory for Cancer Research |
| Avania | Artarmon, Australia | Medical Device Clinical Research |
| Avalign Technologies | Greenwood, IN | Orthopedics & Surgical |
| Salvia BioElectronics | Eindhoven, Netherlands | Migraine Implant |
| Axanton Technology | , | Supposed CEO sent crying emoji when we asked if company was still active |
| Innovac Therapeutics | Cambridge, MA | RNA Therapeutics |
| Chamow & Associates | , | Acquired by Alira Health, Jan 2021 |
| Tolero Pharmaceuticals | , | Rolled in Sumitomo Dainippon Pharma Oncology, Jun 2020; Acquired by Sumitomo Dainippon Pharma, Jan 2017 |
| Q-State Biosciences | , | Renamed Quiver Biosciences, May 2023 |
| Asterias Biotherapeutics | , | Fully absorbed into BioTime Mar 2019; Technology acquired from Geron |
| Solid Biosciences | Charlestown, MA | Gene Therapy, Devices, Biologics, Small Molecules all for DMD |
| Celluris | São Paulo , Brazil | CAR T Cell Therapy |
| Emulate | Boston, MA | Organs-on-chips |
| Accovion | , | Acquired by Clinipace, Apr 2015 |
| Tripos | , | Bought by Certara |
| Titan Pharmaceuticals | , | Merging with private payroll company, Aug 2024 |
| SymPhysis Medical | Galway, Ireland | Minimally invasive, home-use catheter-based drainage devices for palliative care |
| Sitka Biopharma | , | Website gone Jan 2022 |
| TerraGen Discovery | , | Acquired by Cubist Aug 2000, $31M stock |
| Sherpa Clinical | , | Acquired by PCI Pharma Services, Oct 2018 |
| Ablaris Therapeutics | , | Founded and owned by Arrowhead Research |
| InClin | San Mateo, CA | Clinical Research, Consulting |
| iVEAcare | Roseville, MN | Neuromodulation Therapy |
| FLX Bio | , | Renamed RAPT Therapeutics, May 2019 |
| Hermes Pharma | Pullach, Germany | Formulation for Improved Swallowing |
| Amend Surgical | Alachua, FL | Bone Graft Substitute |
| Curio Biotech | Visp , Switzerland | Scientific Services |
| , | Pivoting to apartment ownership and other odd things; Strategic Alts, Aug 2025 | |
| Excelimmune | , | Closed Jul 2016 |
| TAGCyx Biotechnologies | Tokyo, Japan | Oligonucleotide Drug Discovery Platform |
| CooperSurgical | Trumbull, CT | Women's Health and other devices |
| Alligator Bioscience | Lund, Sweden | Antibody Therapeutics |
| Laminar Pharmaceuticals | Palma de Mallorca, Spain | Membrane Lipid Therapy, Synthetic Fatty Acids |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Applied Medical | Rancho Santa Margarita, CA | Surgical Devices |
| Bioprojet SCR | Paris, France | Small Molecules, Injector |
| Zensun Sci & Tech | San Diego, CA | Biologics, Small Molecule |
| Integer | New Ross, Ireland | Medical & Surgical Devices |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| Tanner Pharma Group | Charlotte, NC | International Commercialization Services |
| Oncostat | , | Renamed Recludix Pharma, Mar 2020 |
| , | Website down Jan 2026 - May 2026 | |
| Biosure | , | business filings late Apr 2023, website copyright 2014 in Feb 2025 |
| Remedy Plan Therapeutics | Washington, DC | Metastasis Inhibitor |
| ARCALIS | Fukushima, Japan | Contract mRNA Production |
| IASO Biotherapeutics | Nanjing, China | Fully-human antibody development platform |
| Ocelot Bio | , | Website down Jan 2025 - Jun 2025 |
| Vipragen | Bengalore, India | CRO - discovery, analytical, toxicology, etc |
| InflaRx | Jena, Germany | Antibodies for Inflammation |
| , | Website down Dec 2025 - Apr 2026 | |
| Serqet Therapeutics | , | Renamed Vesalius Therapeutics, Dec 2021 |
| , | Acquired by Grid.ai in reverse merger, Nov 2025; fka First Wave BioPharma; Merged with ImmunogenX, Mar 2024; Merged with AzurRx, Sep 2021, $229M stock, took name | |
| Regulonix | , | Website down Sep 2022 - Feb 2023 |
| Alkermes | Waltham, MA | Small Molecules |
| Amicrobe | , | Renamed Macro Biologics, Mar 2023 |
| Hiteck Pharmaceutical | Wuhan, China | Small Molecules, Biologics |
| Dionex | , | Bought by Thermo Fisher, Dec 2010, $2.1B |
| Genticel | , | Renamed Genkyotex, Feb 2017 |
| NuOrtho Surgical | , | Bankrupt, Feb 2015 |
| Data Intuitive | Lebbeke, Belgium | Data Services |
| SE3D | , | Renamed Seed Therapeutics |
| ExonHit | , | Became Diaxonhit after Exonhit/In Gen Bio merger |
| Ionian Technologies | , | Gone Mar 2016 |
| Aciex Therapeutics | , | Acquired by Nicox, Oct 2014, $120M |
| PRAECIS Pharmaceuticals | , | Acquired by GSK, Dec 2006, $54.8M |
| Chip Diagnostics | , | Website down, LI gone Oct 2024; Penn spinout |
| GITR | , | Combined with HealthCare Pharmaceuticals to become Leap Therapeutics, Jan 2016 |
| Axis-Shield | , | Acquired by Alere, Aug 2011 |
| Corza Medical | Tijuana, Mexico | Surgical Devices |
| NKGEN Biotech | Santa Ana, CA | Autologous and allogenic Natural Killer cell therapy |
| Epiphany Biosciences | , | Website Gone, Sep 2017, Seems gone |
| Dermavant Sciences | , | Acquired by Organon, Oct 2024 |
| Kyras Therapeutics | , | Website gone Aug 2018, no response from CEO, presumed defunct |
| Intuity Medical | , | Website down Aug 2024 - Feb 2025; fka Rosedale Medical |
| Hovione | Osaka, Japan | Contract Manufacturing |
| Serene Medical | , | Website gone Feb 2022; Trying to sell product for a royalty, Dec 2021 |
| SFL Regulatory Affairs & Scientific Communication | , | Acquired by Veristat, Mar 2022 |
| Sympano | , | Biomarkers; Oregon, no site, Nov 2017-Apr 2019 |
| Phio Scientific | München, Germany | Cell Culture Data Acquisition |
| NAMSA | Northwood, OH | Medical Research Organization - Medical Devices |
| D2M Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Evecxia Therapeutics | Durham, NC | Slow-release |
| BioMarin Pharmaceutical | Novato, CA | Biologics |
| Audion Therapeutics | , | 10 years, no progress, no full-time employees |
| Phenex Pharmaceuticals | , | Website down Nov 2022 - Apr 2023 |
| Quanticel Pharmaceuticals | , | Acquired by Celgene, $100M +$300M milestones, Apr 2015 |
| Nya Cell Therapeutics | , | No info |
| CryoStasis | Ottawa, ON | Cold Storage Technology |
| CoaguSense | Fremont, CA | Coagulation monitor |
| TopoTarget | , | Merged with BioAlliance Pharma to become Onxeo |
| Cell Assay Innovations | , | Founder and only main employee gone, Dec 2021 |
| Unither Pharmaceuticals | Nanjing, China | CDMO |
| MileCell Biotech | Shanghai, China | Cells, Matrices, Reagents |
| BGI | Kobe, Japan | Genetic Testing |
| Actavalon | , | Shut down Dec 2020 |
| Frontera Therapeutics | Watertown, MA | Gene Therapy Development |
| Sopharma | Sofia, Bulgaria | Generics |
| Johnson & Johnson MedTech | West Chester, PA | Implants, Biomaterials |
| B2S Life Sciences | Franklin, IN | Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics |
| SK Pharmteco | Corbeil-Essonnes, France | Viral Vectors |
| Medica | , | Gone before 2019 |
| Icos | , | Acquired by Eli Lilly, 2006, $2.2B |
| Senolytic Therapeutics | , | Website down Sep 2021 - Feb 2022; licensed product to Rejuveron/Rejuversen |
| , | Acquired by Genesis Drug Delivery & Development, Jan 2021 | |
| AIMM Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| ImmunoGen (2) | , | Acquired by AbbVie, Feb 2024, $10.1B |
| MicrofluidX | , | Renamed MFX |
| Adhereon | , | Website down Feb 2022 - Jul 2022 |
| Immutics | , | Renamed TrueBinding |
| Aureon Biosciences | , | Insolvency Proceedings |
| , | Renamed SylamoreBio | |
| Corcept Therapeutics | Redwood City, CA | Small Molecules |
| CLCbio | , | Acquired by Qiagen, 2013 |
| Repair Biotechnologies | Syracuse, NY | Cholesterol Therapies |
| BioRexis | , | Acquired by Pfizer, Feb 2007 |
| Innorna | Hong Kong, China | Lipid Nanoparticles |
| MetaboGen | , | Subsumed into parent company, May 2024 |
| Sorbent Therapeutics | , | Gone post 2014 |
| Arthrex | Naples, FL | Arthroscopy Devices |
| Azenta Life Sciences | Waltham, MA | Sample Management, Automation, Storage |
| American Peptide Company | , | Acquired by Bachem, Feb 2015 |
| Zymequest | , | Renamed Velico Medical, Dec 2009 |
| Alcyone Lifesciences | , | Renamed Alcyone Therapeutics, Jan 2021 |
| ACIC Pharmaceuticals | Brantford, ON | Contract Manufacturing of Small Molecules and APIs |
| BioSynthema | , | No news since 2007 as of Jul 2020 |
| ProCrysta Biologix | , | Shut down 2018 |
| PreComb Therapeutics | Hombrechtikon, Switzerland | Patient-specific 3D functional drug testing of microtumors |
| Neopharm Labs | Blainville, QC | Pharmaceutical testing Lab |
| Cepheid | Sunnyvale, CA | Molecular Diagnostics |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Epygenix Therapeutics | , | Acquired by Harmony Biosciences, Apr 2024 |
| Glide Pharma | , | Renamed Glide Technologies |
| Acme Bioscience | Palo Alto, CA | Medicinal chemistry, custom synthesis |
| , | Merged into Meridian Bioscience | |
| Minka Therapeutics | , | No updates 2018 - Feb 2025; One employee who has anopther job; fka Innavirvax |
| Cryoniss | Deeside, UK | Bio Banking |
| Trizell | , | Website gone Mar 2023; Empty Website, Aug 2019 - Dec 2021; UK based |
| Tanner Pharma Group | Redbourn, UK | International Commercialization Services |
| CD4 Therapeutics | Starnberg, Germany | T Reg for Autoimmune |
| Biomet | , | Bought by Zimmer, Apr 2014, $13.4B - combined company renamed Zimmer Biomet |
| DaVita Clinical Research | Minneapolis, MN | Clinical Research |
| , | Acquired by Adams Clinical Research, Sep 2025?; Website down Aug 2025 - Sep 2025 | |
| Immunovant | Durham, NC | Monoclonal Antibody |
| BioBam Bioinformatics | Valencia, Spain | Bioinformatics Software |
| Trinity Biotech | Bray, Ireland | Diagnostics |
| ThermoGenesis | , | Defaulted and taken over Jul 2024; Merged with TotipotentRX Jul 2013, Renamed CESCA Therapeutics, then changed name back |
| , | Website down Dec 2025 - Apr 2026; Privatized Apr 2025; Acquired by invoX Pharma, Mar 2023, $161M | |
| PepLib Biotech | Metuchen, NJ | Peptides |
| Emerald Biostructures | , | Acquired and renamed Beryllium |
| Surgical Innovation Associates | , | Acquired by Integra LifeSciences, Dec 2022 |
| Upstate Biotechnology | , | Closed 2005 |
| , | Website taken over, Feb 2026 | |
| Biotel | , | Acquired by CardioNet, 2010 |
| Iberica US | , | Website copyright 2004 (as of 2018) |
| Bresagen Ltd | , | Bankrupt Jan 2004, Acquired by Hospira, Oct 2006 |
| Ziran Biopharmaceutical | , | Dissolved, Dec 2020 |
| IBSA Institut Biochimique | Lugano-Pazzallo, Switzerland | Various Treatments and Nutraceuticals |
| FluoroPharma | , | Shell Company |
| Nature's Toolbox | Rio Rancho, NM | Biomanufacturing Technology |
| iQone Healthcare Group | Versoix, Switzerland | Biosimilars |
| Viant Medical | Westfield, PA | Contract Medical Devices |
| Biomimetic Therapeutics | , | Acquired by Wright Medical group Apr 2013 |
| Molecular Sensing | , | Business revoked Aug 2019 |
| Novogene | Beijing, China | Genomic Services |
| SafeRx Pharmaceuticals | , | No news 2021 - Feb 2025, never registered in MA |
| Vernacare | Chorley, UK | Surgical Devices |
| AstronauTx | London, UK | Alzheimer's Treatments |
| Artisan Bio | , | Assets Acquired by Cellistic, Apr 2024 |
| SamanTree Medical | Lausanne, Switzerland | Margin Assessment |
| AvidBiotics | , | Split to become Xyphos and Pylum Biosciences, Nov 2017 |
| Adocia | Lyon, France | Molecular Delivery System for Therapeutic Proteins |
| Coherus Oncology | Redwood City, CA | Biologics, Biosimilars |
| MorphImmune | , | Merged with Immunome, Oct 2023 |
| Annidis | , | Effectively bankrupt, Feb 2018 |
| Newomics | Berkeley, CA | Innovative and integrative platforms and solutions for personalized healthcare |
| MerachemSyncom | , | Renamed Symeres, Dec 2020 |
| BioNxt Solutions | Vancouver, BC | Drug formulations, diagnostics, drug delivery, psychologic |
| Semaphore Solutions | Victoria, BC | Lab Software |
| Lynx Biosciences | San Diego, CA | Phenotypic profiling and functional characterization of suspension cells |
| AlphaMed Pharmaceuticals | , | Embroiled in lawsuit with Arriva in 2006, seems gone |
| sRNAlytics | , | Renamed Gatehouse Bio, 2019(?) |
| Cereno Scientific | Mölndal, Sweden | Small Molecule |
| Hua Medicine | Shanghai, China | Small Molecules |
| Metera Pharmaceuticals | , | Shut down Nov 2020 |
| Dropshot Therapeutics | , | |
| Corridor Pharmaceuticals | , | fka Argenetix, gone |
| TearClear | , | Website down Dec 2024 - Jun 2025; Seem to be in FL also - not registered in MA or FL |
| Bio Genuine Biotech | Pingdingshan, China | Small Molecules |
| Turn Medical | San Antonio, TX | Development of automated prone positioning systems for critically ill patients with respiratory distress |
| Canon Medical Systems | Tustin, CA | Medical imaging tech company |
| Labor Dr. Merk | , | Acquired by Boehringer Ingelheim, Dec 2020 |
| Aristea Therapeutics | , | Dissolved, Feb 2023 |
| ViGeneron | , | Renamed VeonGen, May 2025 |
| Emas Pharma | , | Sold to PE Dec 2024; Acquired by Bionical, Nov 2016 |
| Gate Neurosciences | , | Renamed Syndeio Biosciences, May 2025 |
| Experic | Cranbury, NJ | CDMO, clinical trial supply services, formulation and process development, analytical services |
| Nuevocor | Singapore, Singapore | AAV-based gene therapy |
| , | Acquired by Roche, Jan 2024, $2.7B + $400M milestones | |
| Remo CRO | , | Seems to be rebranded as Supeira |
| med fusion | , | Acquired by Quest Diagnostics, Jul 2017 |
| Baccinex | , | Acquired by Adragos Pharma, Nov 2024 |
| Zenshine Pharmaceuticals | Hangzhou, China | Small Molecules |
| GSK | Rixensart, Belgium | Small Molecules, Vaccines, Biologics |
| Innate Pharma | Marseille, France | Monoclonal Antibodies |
| Fresenius Kabi | Sanitago, Chile | Contract Manufacturing |
| Microbia-pe | , | Renamed Microbia |
| Aruna Bio | Athens, GA | Exosome Therapeutics |
| Avema Pharma Solutions | , | Renamed PLD Pharma Services |
| Suanfarma | Madrid, Spain | Development, production, and commercialization of ingredients for pharmaceutical, veterinary, and nutritional industries |
| Orchard Therapeutics | London, UK | Ex-vivo autologous hematopoietic stem cell gene therapy |
| Scala Biodesign | Tel Aviv, Israel | Protein Design Software |
| MapLight Therapeutics | Burlington, MA | Optogenetics |
| , | Website down Oct 2025 - Feb 2026 | |
| Harmony Labs | , | Now Ei |
| Elusys Therapeutics | , | Acquired by Heat Biologics, Apr 2022 |
| Array Genomics | , | Website down Dec 2022 - Apr 2023 |
| PsyBio Therapeutics | , | Shell company, Jun 2024; Website down Jan 2024 - May 2024 |
| Cascadian Therapeutics | , | Bought by Seattle Genetics, Feb 2018, $614m stock |
| Sure Genomics | , | Gone 2014? |
| Biotrial | Laval, QC | Small and large molecule bioanalysis in GLP environment |
| Topstone Research | , | Acquired by Veristat, Oct 2018 |
| Physiomics | Oxford, UK | Cancer Treatment Prediction |
| Tikcro Technologies | , | Liquidating 2021 |
| CymoGen Dx | , | Acquired by Biocare Medical, Mar 2015 |
| Precision Medical Products | Carrollton, TX | Blood Clot Prevention Device |
| , | Renamed Coiled Therapeutics, Mar 2026 | |
| Gracell Biotechnologies | , | Acquired by AstraZeneca, Feb 2024, $1.2B |
| Sun Pharmaceuticals | Dhaka, Bangladesh | Generic Small Molecules, APIs |
| Protenium Clinical Research | , | Acquired by Eligo Health Research, Jan 2019 |
| Bionode | , | Shut down Mar 2024 |
| Cadrock | , | Website down Mar 2020 - Feb 2021 |
| Tyme Technologies | , | Merged with Syros, Sep 2022 |
| PharmaKinetics Laboratories | , | Acquired by BASi, Jun 2002? |
| Memic | , | Renamed Momentis Surgical, Jul 2022 |
| Bochum, Germany | Acquired by Wallaby Medical, Apr 2022 | |
| AlloThera | , | Gone, 2018 |
| Eurand | , | Now Aptalis |
| Bioreclamation | , | Merged with Celsis IVT and became BioreclamtaionIVT |
| SN BioScience | Seongnam, Korea | Double Core-Shell Micelle, Liposomes, Albumin, LNP |
| Grace Bio-Labs | Bend, OR | Slides, Microplates, Cell Analysis Equipment |
| DDi | Singapore, Singapore | Clinical Software |
| Pyrotech Therapeutics | Beijing, China | Small Molecule Drugs, Gene Regulation Therapies-Innate Immunity & Pyroptosis Modulators |
| Valitor | Berkeley, CA | Protein therapeutics |
| Molecular Medicine | , | Acquired by AGC Biologics, Sep 2021; aka MolMed |
| Berlin Heart | The Woodlands, TX | Ventricular assist devices |
| ACROBiosystems | Newark, DE | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| OxOnc Services Company | , | Virtual company that may not longer be active |
| Resilience | Alameda, CA | Biomanufacturing |
| CereXis | , | Website down Oct 2021 - Jul 2022 |
| Cellink | Kyoto, Japan | Bioprinting |
| Evidentic | Potsdam, Germany | Therapeutic Antibodies for Research/Reference Use |
| , | Website hijacked Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Deep Genomics | Toronto, ON | AI-discovery, Oligonucleotide Therapies |
| Captor Therapeutics | Allschwil, Switzerland | Targeted Protein Degradation |
| Co-D Therapeutics | , | Professor-run, 10 years, nothing happened 2013-2023 |
| Awaken Immunity | , | Website down Mar 2025 - Jul 2025 |
| Immunexpress | Seattle, WA | Sepsis diagnosis |
| Pace | Frontenac, KS | Analytical Testing, CDMO |
| Cerba Research | Ghent, Belgium | Lab Testing |
| BrightInsight | San Jose, CA | Digital Health Platform |
| Anatomics | Melbourne, Australia | Implants, Surgical Devices |
| , | Website down Jan 2026 - May 2026 | |
| , | Gone before Dec 2025 | |
| MeiRui Pharma | , | Bought by GSK |
| STARLIMS | Hollywood, FL | LIMS |
| Zyagen | San Diego, CA | Life Science Reagents |
| Amplified Proteomics | , | Shut down Jan 2006 |
| , | Acquired by Merck, Jan 2026, $9.2B; Formerly K2 Therapeutics. Relocated from Boston to San Diego | |
| GlaxoSmithKline | , | Renamed GSK, May 2022 |
| NitroCell Bioscience | , | Changed name to AOBiome, May 2013 |
| mAIbe | Rome, Italy | Monoclonal Antibodies for Viruses |
| BioNTech | San Diego, CA | mRNA, Vaccines, Biologics |
| Alvogen | Morristown, NJ | Generics, OTCs |
| GlobalCare Clinical Trials | , | Acquired by Covance, Jul 2020 |
| SeSaM-Biotech | Aachen, Germany | Protein Engineering |
| Biocept | , | Chapter 7 Bankruptcy, Oct 2023 |
| Cornerstone BioPharma | , | Now Cornerstone Therapeutics |
| Cytel | Geneva, Switzerland | Clinical software, statistical services |
| Norgine | Lisbon, Portugal | Specialty Pharma |
| Palette Life Sciences | , | Acquired by Teleflex, Oct 2023, $600M |
| |
Montréal, QC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| ELAA Technology | , | Website down Jun 2024 - Dec 2024 |
| Spire Health | , | Acquired by Wellinks, Sep 2024 |
| Global Pharma Tek | Hyderabad, India | Contract Research, Clinical Research, Consulting |
| Lytica Therapeutics | Cambridge, MA | Antimicrobial peptide Design |
| BIOS Health | Cambridge, UK | Neural interface platform |
| Bright Peak Therapeutics | Basel, Switzerland | Engineered cytokines for immuno-oncology indications |
| Link Cell Therapies | South SF, CA | Cell Therapies focused on CAR T, oncology |
| ShiraTronics | Minneapolis, MN | Migraine Device |
| Medicenna Therapeutics | Vancouver, BC | Immuno-oncology therapies |
| NeuroGenesis Bio | Rochester, NY | Bone Marrow Cell Therapy |
| Kailera Therapeutics | San Diego, CA | Peptides, Small Molecules |
| Denali Therapeutics | South SF, CA | Neurodegenerative therapies, BBB-crossing antibody |
| Taiho Oncology | Princeton, NJ | Oncology small molecules |
| , | Website down Nov 2025 - Mar 2026 | |
| BiBo Pharma | Shanghai, China | Biologics CDMO |
| Amgen | Burnaby, BC | Small Molecules, Biologics |
| Ossium Health | Indianapolis, IN | Bone Marrow-derived Stem Cells |
| RHDL Therapeutics | , | No website Dec 2019 - May 2023, Fannin Innovation Studio company |
| VascVersa | Belfast, Ireland | Cell Therapies to Promote Vascular Regeneration |
| Praha Vaccines | , | Acquired by Novavax, Jun 2020 |
| CenterVue | , | Merged into iCare, Apr 2020 |
| Epic Pharma | Laurelton, NY | Generics |
| Roswell Biotechnologies | , | Shut down late 2022 |
| Prescient Neuropharma | , | Acquired and renamed, pivoted to mining |
| Sinorda Biomedicine | Taicang City, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Formation Biologics | , | Rebranded as Forbius |
| Loop Therapeutics | , | Shut down Jan 2021 |
| JSI Research Chemicals | Brantford, ON | Chemical synthesis, analytical, and process development |
| Nanosonics | Gif sur Yvette, France | Ultrasound |
| Drug Delivery Experts | , | Acquired by Pace Analytical, Jul 2021 |
| Trueline Therapeutics | , | Website down Apr 2024 - Sep 2024; claim additional Cambridge, MA location but employees are in Berlin & Florida |
| Tramontane Therapeutics | , | Acquired by Kriya Therapeutics, Sep 2023 |
| ImmproNano | , | Website Gone Jun 2021 - Oct 2021 |
| Cliantha Research | Saint Petersburg, FL | Clinical Research & Services |
| ForDoz Pharma | East Windsor, NJ | Development, manufacturing, and commercialization of value-added sterile complex injectable products |
| Piramal | Pithampur, India | CDMO |
| UMN Pharma | , | Liquidating Apr 2025 |
| Oncodesign | , | Renamed Oncodesign Services, Mar 2022 |
| Emery Pharma | Alameda, CA | CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) |
| Advanced Cardiac Therapeutics | , | Renamed EPIX Therapeutics, Aug 2018 |
| Vaxil Bio Therapeutics | , | Acquired by Data Center Company for ticker |
| Spectrum Pharma | Montréal, QC | Pharmaceutical Packaging |
| Sancilio & Company | , | Renamed Micelle BioPharma |
| Lumenis | Hong Kong, China | Energy-based medical treatments |
| MiniMed | Northridge, CA | Diabetes Management |
| Matinas Biopharma | Bedminster, NJ | Dyslipidemia treatments |
| Minerva Biolabs | Berlin, Germany | Contamination Control, PCR Products, DNA/RNA Extraction |
| PureIV | , | Website down Apr 2023 - Sep 2023 |
| STI Pharma | Newtown, PA | Acquisition, Development & Marketing of Specialty Pharmaceuticals |
| SalioGen Therapeutics | , | Shut down late 2024 |
| Fuse Biotherapeutics | , | Website down, Oct 2024 - Jul 2025 |
| invIOs | Vienna, Austria | Novel cancer immunotherapies, cell, siRNA, peptides |
| MSD | Ballydine, Ireland | Small Molecules |
| IQVIA | Lenexa, KS | Clinical Research |
| Synlogic | , | Shut down Sep 2024 |
| Cayman Chemical | Ann Arbor, MI | Biochemical Tools |
| Serenity Pharmaceuticals | , | Acquired by Acerus, Mar 2022 |
| Accro Bioscience | Suzhou, China | Small Molecules |
| Dompé | Boston, MA | Biologics, Small Molecules, OTC |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Achillion Pharmaceuticals | , | Acquired by Alexion, Jan 2020, $930M |
| Telum Therapeutics | Noáin, Spain | Bacteriophages |
| Nextbiotics | , | Website down Aug 2022 - Nov 2022 |
| TR Biosurgical | , | Website Taken Over |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Protein Advances | , | Changed name to PAI Life Sciences, Apr 2014 |
| Geno Pharmaceuticals | Mapusa, India | Generics |
| Bacthera | , | Liquidating, Feb 2025 |
| Enquyst Technologies | North Brunswick, NJ | Biologics Manufacturing |
| AtriCure | Mason, OH | Cardiovascular Devices |
| NovoKera | , | Merged into Longevity Biomedical |
| Miromatrix Medical | , | Acquired by United Healthcare, Dec 2023, $91M |
| Novoste | , | Gone 2008; fka Best Vascular Novoste |
| Proscia | , | |
| Omega Bio-Tek | Norcross, GA | IVD Products |
| MX Orthopedics | , | Website Gone, Mar 2017 |
| AAVLife | , | Renamed Annapurna |
| Cellphire Therapeutics | Rockville, MD | Platelet Stabilization Technology |
| , | Acquired by Precision Cell Systems, Sep 2025 | |
| Ernexa Therapeutics | Cambridge, MA | mRNA Technology |
| PK MED | Paris, France | Custom-designed, injectable, and biodegradable micro-implants |
| Aspen Neuroscience | San Diego, CA | Autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy |
| Betta Pharmaceuticals | Hangzhou, China | Small Molecules |
| Worldwide Clinical Trials | Cambridge, MA | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| JRS Pharma | Rosenberg, Germany | Excipients & Coatings |
| Biopar | , | Gone? |
| INC Research | , | Merged with inVentiv Health, May 2017, renamed Syneos Health |
| ReliaTech | Wolfenbüttel, Germany | Proteins, ELISA, antibodies, contract work |
| Sova Pharmaceuticals | , | Shut down Dec 2020 |
| LifeMax | , | Part of AmMax |
| Sanivo Pharma | , | Website down Apr 2023 - Sep 2023 |
| Lumibird Medical | Cournon d’Auvergne, France | Ophthalmic devices |
| Keratin Biosciences | , | Allegedly formed out of merger of MicroChips Biotech & KeraNetics, Jul 2018 but never had website and Microchips was acquired by Dare Bioscience, Nov 2019 |
| Schwartz Pharma | , | Acquired by UCB, 2006, €4.4B |
| Validus Cellular Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Roche | Mississauga, ON | Small Molecules |
| Dalriada Drug Discovery | Mississauga, ON | Drug Discovery Services |
| TandemAI | Suzhou, China | AI to democratize the drug development process |
| TotipotentRX | , | Merged with Thermogenesis, Jul 2013 to become CESCA Therapeutics |
| Orchid Orthopedic Solutions | Oregon City, OR | Contract Medical Device Work |
| TCS Biosciences | Buckingham, UK | Laboratory reagents, quality control products, and test kits |
| Carlsbad Technology | Carlsbad, CA | Generics, CMO |
| , | Pivoted to defense, Feb 2026 | |
| Vector Oncology | , | Renamed Concerto HealthAI |
| Eppendorf | Leipzig, Germany | Wide Range of Scientific Products |
| MarDx | , | Acquired by Fitzgerald Industries, 2007 |
| Meribel Pharma Group | Alcala, Spain | Contract Manufacturing |
| Genencine Therapeutics | , | No website Dec 2019 - May 2023 |
| GeneEx | , | Now RevDia |
| Indigo Biosciences | State College, PA | Nuclear Receptor Assays |
| Verogen | , | Acquired by Qiagen, Jan 2023, $150M |
| Fluxergy | Irvine, CA | Diagnostic Lab-in-a-box |
| Francis Medical | Maple Grove, MN | Water Vapor Prostate Ablation |
| LightMed | , | |
| Meda Pharmaceuticals | , | Acquired by Mylan, Aug 2016 |
| Marqmetrix | , | Acquired by Thermo Fisher, Jun 2023 |
| Biosynth | Gardner, MA | Antibodies & Peptides |
| NanoMed Targeting Systems | , | Website down Jun 2021 - Dec 2021 |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| ChemPacific | Baltimore, MD | Chemicals |
| BlinkBio | , | Shut down Jan 2021; fka Coferon |
| BL&H | , | Website down Sep 2022 - Feb 2023 |
| CYTLIMIC | , | Website down Oct 2022 - Apr 2023 |
| CytoSen Therapeutics | , | Acquired by Kiadis Pharma, Jun 2019 |
| Axcentua | , | Website down Jan 2020 - Sep 2020 |
| Nanosphere | , | Acquired by Luminex, Jun 2016 |
| Aerie Pharmaceuticals | , | Acquired by Alcon, Nov 2022, $770M |
| Vai Therapeutics | , | No website Oct 2019 - Aug 2021 |
| Gritgen Therapeutics | Suzhou, China | Gene Therapy |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Gyrus | , | Acquired by Olympus, 2008, $2B |
| Esperion Therapeutics (2) | Ann Arbor, MI | Bacteriome |
| Aether Biomachines | Menlo Park, CA | Enzyme engineering, enabling customers to manufacture complex & novel products at fractional cost. |
| APEX Medical | , | Renamed Wellell, Jan 2022 |
| Genascence | Palo Alto, CA | Musculoskeletal Gene Therapies |
| Celest Therapeutics | , | |
| Regenesis | Scottsdale, AZ | Pain-Alleviating Electromagnetic Device |
| Waterstone Pharmaceuticals | Wuhan, China | Small Molecules, APIs |
| Alethia Biotherapeutics | Montréal, QC | Monoclonal Antibodies |
| Tonus Therapeutics | , | Lead molecule acquired by Akashi Therapeutics, Sep 2014, no indication they remain active |
| Gravidas Diagnostics | , | preeclampsia POC test |
| InVivo Biosystems | Eugene, OR | Devices, consumables, and software for worm screening and phenotyping |
| Libra Clinical Research Associates | , | Gone |
| Augmedics | Yokneam, Israel | Augmented Reality Surgical Guidance System |
| vantix DIAGNOSTICS | , | Website down Aug 2020 - Feb 2021 |
| CancerVacs | , | Never officially registered as a business in CA. Effectively became AlleCures in 2017 |
| accuFD | , | Closed Dec 2017 |
| Integra LifeSciences | San Diego, CA | Medical Devices |
| Kadence Bio | London, UK | Treatment for Premature Eja |
| , | Liquidating Jan 2026 | |
| AlveoliX | Biel, Switzerland | Organ-on-a-chip |
| Sapec | , | Merged with Bioferment & Cernitin in 1994 to become Cerbios-Pharma |
| Kriya Therapeutics | Redwood City, CA | Gene Therapy |
| Escape Therapeutics | , | Website gone, Dec 2015 |
| Biolase | Foothill Ranch, CA | Dental Lasers |
| JDP Therapeutics | , | Seems gone, Jun 2019 |
| Sabiad | Heerenveen, Netherlands | Theranostics |
| Scribe Therapeutics | Alameda, CA | CRISPR platform |
| , | Shut down Sep 2025; fka GenoFAB | |
| Natrix Separations | , | Acquired by Merck KGaA/MilliporeSigma, Aug 2017 |
| PeriGen | Cary, NC | Perinatal Devices |
| Prellis Biologics | Berkeley, CA | 3D printed vasculature, Antibody Discovery Platform |
| F1 Oncology | , | Rebranded as Exuma Biotechnology, late 2019 |
| Cepham Life Sciences | Fulton, MD | Lab Research products, Antibodies, Reagents, Services |
| Cirdan | Lisburn, UK | Pathology, Imaging |
| Jiangxi Jimin Kexin Group | , | No website Oct 2019 - May 2023 |
| SkylineDx | Rotterdam, Netherlands | Diagnostics |
| Seer | Redwood City, CA | Early Detection |
| TiumBio | Seongnam, Korea | Small Molecules, Biologics |
| ConfometRx | Mountain View, CA | Structure-based drug development tools |
| miRNA Scientific | North Brunswick, NJ | RNA Profiling Technology for Cancer Diagnosis |
| Oxford Brain Diagnostics | Oxford, UK | Diagnostics |
| , | Website down Dec 2025 - Apr 2026 | |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| VALANX Biotech | Klosterneuburg, Austria | Bioconjugation |
| Micro Therapeutic Research Labs | Chennai, India | Bioavailability, Bioequivalence |
| , | Shut down Mar 2026 | |
| Cellex Cell Professionals | Cologne, Germany | Cell Manufacturing, Products |
| Kitov Pharmaceuticals | , | Renamed Purple Biotech, Dec 2020 |
| Voronoi | Incheon, Korea | Small Molecule Inhibitors |
| , | Website down May 2025 - Dec 2025 | |
| ThioMatrix | Innsbruck, Austria | Drug Delivery |
| SQI Diagnostics | , | Website hijacked Nov 2024; Website down Aug 2024 |
| Nura | , | Acquired by Omeros |
| , | Closed June 2024 | |
| Excelra | Utrecht, Netherlands | Data Science & Informatics Services |
| Advanced Sterilization Products | Irvine, CA | Sterilization Products |
| Tocagen | , | Merged with Forte Biosciences, Jun 2020 |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Sengenics | , | Merged into Standard BioTools, Nov 2024 |
| Cearna Aesthetics | , | Product acquired by Allergan |
| Coloplast | Tatabánya, Hungary | Wound care, surgical, bladder, bowel devices |
| Lightcast Discovery | Cambridge, UK | Microdroplet Manipulation, Cell Sorting |
| MicroPort | Saluggia, Italy | Medical Devices |
| Vernacare | Bolton, UK | Surgical Devices |
| Comparative Biosciences | Sunnyvale, CA | GLP and non-GLP preclinical toxicology, efficacy, pharmacology, histopathology, and safety studies on all laboratory species. |
| Medley Genomics | , | Website for sale Feb 2021 |
| Jaleva Pharmaceuticals | , | Gone |
| Alnylam Pharmaceuticals | Zug, Switzerland | RNAi |
| Natsimbio | , | Russian vaccine maker, no website Aug 2019 - May 2023 |
| Certara | Durham, NC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| AdvanceCOR | Planegg, Germany | Therapeutics & Diagnostics for Cardiovascular Indications |
| Mint Diagnostics | , | Liquidating, Aug 2023 |
| Boundless Bio | San Diego, CA | Cancer Treatments targeting extra-chromosomal DNA |
| IntoCell | , | Website down Aug 2023 - May 2024 |
| Genaco Biomedical | , | Acquired by Qiagen 2006 |
| Epicrispr Biotechnologies | South SF, CA | Therapies to control gene expression |
| Keyu Biological Engineering | Zhuhai, China | Body Fluid Analyzers |
| Kalyra Pharmaceuticals | , | Website gone May 2022, founder has new C-level job elsewhere, no progress 2011-May 2022 |
| DifGen Pharmaceuticals | Hyderabad, India | APIs, Formulated Generics |
| EKG Labs | , | Acquired by Infinity Life Sciences, Jun 2022 |
| ProNovus Bioscience | , | Shut down Dec 2019 |
| Hillrom | , | Acquired by Baxter, Dec 2021, $12.5B |
| Qidni Labs | , | Website down Oct 2021 - Jul 2022 |
| Genevant Sciences | Vancouver, BC | RNA Therapeutic Delivery technology |
| Taconic Farms | , | Changed name to Taconic Biosciences |
| , | Website down May 2025 - Dec 2025 | |
| Gensco Pharma | Doral, FL | Transdermals |
| , | Website taken over Feb 2026 | |
| Allakos | , | Acquired by Concentra, May 2025, $35M |
| Lumara Health | , | Bought by Amag, Sep 2014, $675M |
| Novo Nordisk | Værløse, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Sireau Labs | , | Website down Mar 2025 - Aug 2025 |
| Symvivo | , | Website down May 2024 - Sep 2024 |
| Inhalon Biopharma | Morrisville, NC | Biologics |
| , | Acquired by Xoma, Sep 2025 | |
| Protedyne | Bloomfield, CT | Robots for Processing Diagnostic Tests |
| Fuji Pharma | , | Renamed ISIS, Jul 2019 (for real), no website |
| Anthra Pharmaceutical | , | Gone |
| AtriCure | Amsterdam, Netherlands | Cardiovascular Devices |
| Biosynth | Lelystad, Netherlands | Peptide-based products and services, epitope mapping, peptide discovery & GMP peptides |
| Denovo Biolabs | Bangalore, India | Cell Assays, Antibody Research, Lab products |
| Ariana Pharma | Paris, France | Clinical & Biomarker Data Analytics |
| Savara Pharmaceuticals | Langhorne, PA | Inhalable Delivery |
| Aston Sci. | Seoul, Korea | Therapeutic cancer vaccines and proteostasis modulators |
| AnC BIO | , | Korean company that apparently defrauded investors in Vermont, gone or effectively gone |
| iRhythm Technologies | Deerfield, IL | Remote heart analysis |
| Prolexys Pharmaceuticals | , | Website Gone |
| Sage-N Research | Milpitas, CA | AI & Mass Spec for Biomarker Discovery |
| AM-Pharma | Utrecht, Netherlands | Alkaline Phosphatase |
| Coloplast | Mulgrave, Australia | Wound care, surgical, bladder, bowel devices |
| Telo Genomics | Toronto, ON | Diagnostics |
| , | Website down May 2025 - Dec 2025 | |
| Tasly Pharmaceutical | Rockville, MD | Small Molecules, Generics |
| Relisys Medical Devices | Hyderabad, India | Cardiovascular medical devices |
| chromocenter | , | Merged into Sumika Chemical Analysis Services, Oct 2023 |
| Panakeia | Cambridge, UK | in silico multi-omics |
| Proximagen | , | Acquired by Upsher-Smith, Aug 2012; Originally spun out of King's College London |
| , | No news Mar 2021 - Jan 2026 | |
| Pursuit Vascular | , | Acquired by ICU Medical, Nov 2019, $75M |
| |
Suzhou, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Arizona Cancer Therapeutics | , | Website Gone Sep 2017; Presumed an SBIR one and done |
| Delpharm | Gaillard, France | Contract Manufacturing |
| GeneTrace Systems | , | Dissolved Dec 2003 |
| Median Technologies | Valbonne, France | Imaging Phenomics |
| Chemi Peptides | , | Website down Mar 2023 - Sep 2023 |
| MicroOptx | , | Website down Dec 2022 - Apr 2023 |
| |
Gronau, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Treadwell Therapeutics | Toronto, ON | Oncology Small Molecules |
| Cleveland Biolabs | , | Acquired by Cytocom via Reverse Merger, Oct 2020 |
| DxNow | , | Renamed ZyMot fertility |
| RevBio | Lowell, MA | Biocompatible Bone Adhesive |
| GenoLogics | , | Acquired by Illumina, Sep 2015 |
| Ansh Labs | Webster, TX | Diagnostics Products |
| Proteonomix | , | Shell Company |
| Orizuru Therapeutics | Kanagawa, Japan | IPS Cell Therapy for Heart Failure |
| Inotiv | St. Louis, MO | Contract lab services, Scientific Instruments |
| CinCor Pharma | , | Acquired by AstraZeneca, Feb 2023 |
| Neurana Pharmaceuticals | , | Website down Oct 2022; Strategic Alts, Mar 2022 |
| Viant Medical | Collegeville, PA | Contract Medical Devices |
| Antisoma | , | Became investment company |
| Nora Therapeutics | , | Website gone, Most of management team moved to Menlo Therapeutics |
| BN-ImmunoTherapeutics | , | Absorbed into Bavarian Nordic, 2010? |
| Biolex Therapeutics | , | Bankruptcy Liquidation 2012 |
| NTC | Milan, Italy | Generics |
| PeLeMed | Gwangju, Korea | Viral and Cancer Drugs |
| InGeneron | Houston, TX | Stem cell collection and processing technology, Therapy |
| Ephicacy | Bangalore , India | Consulting Biostatistics, SAS Programming, Data Migration, CDISC Data Conversion and Clinical Data Management |
| Optiscan Imaging | Greenville, DE | Single-Cell Imaging |
| Grifols | Durham, NC | Biologics |
| PREMIER Biosoft | Indore, India | Mass Spectrometry, Genomics Software |
| Endogena Therapeutics | Zurich, Switzerland | Regenerative Medicine |
| Shoreline Biosciences | San Diego, CA | Cell-Based Immunotherapies |
| Celares | , | Acquired by Biosynth, Jul 2023 |
| Respivant Sciences | , | Drug failed, website down Dec 2020 - Apr 2021; fka Patara Sciences, Roivant acquired and owned |
| Artecel Sciences | , | Shut down 2002, assets sold 2003 |
| L.E.A.F. Pharmaceuticals | , | Website down Aug 2025, last news 2020 |
| Zenomics | , | Website down Jan 2023 - Jul 2023 |
| , | Website gone Feb 2026 - Apr 2026 | |
| Inotec AMD | Cambridge, UK | Oxygen Wound Therapy |
| Rancho BioSciences | San Diego, CA | Curation of Health and Research Data |
| Cerebrus CNS Drug Discovery | , | Acquired by Vernalis |
| Aesku Diagnostics | Des Plaines, IL | Research Diagnostics |
| Cyteir Therapeutics | , | Shut down Mar 2024 |
| ALK Abello | Hørsholm, Denmark | Allergy Diagnostics, Treatments |
| TauTaTis | , | Shut down 2011 |
| Avista Therapeutics | Pittsburgh, PA | Gene Therapy Delivery |
| Armgo Pharma | , | Renamed RyCarma Therapeutics, Jan 2025 |
| Sirnaomics | Germantown, MD | RNAi Therapeutics |
| Creativ-Ceutical | , | Website down Dec 2022 - Apr 2023 |
| APT Therapeutics | , | Shut down Mar 2019 |
| Nanoly Bioscience | , | Website down Feb 2023 - Jul 2023 |
| QuantaLife | , | Acquired by Bio-Rad, Oct 2011, $162M |
| Meristem Therapeutics | , | Defunct |
| Fresenius Kabi | Blonie, Poland | Contract Manufacturing |
| InVivo BioTech Services | Hennigsdorf, Germany | Contract Manufacturing Organization for antibodies, recombinant proteins and final immunoassay kits |
| Navitas Life Sciences | Hampshire, UK | Decentralized Clinical Research, Consulting |
| PathoGene | , | Website taken over, Oct 2017 |
| Cancer Prevention Pharmaceuticals | , | Acquired by Panbela Therapeutics, Jun 2022 |
| Semma Therapeutics | , | Acquired by Vertex, Sep 2019, $950M |
| DC Biosciences | , | Shut down Jul 2023 |
| Halloran Consulting Group | Boston, MA | Consulting |
| Binnacle Biosciences | , | No website, Apr 2018-Dec 2019 |
| Shield Diagnostics | , | Website down Feb 2020 - Aug 2020 |
| Dualsystems Biotech | Schlieren, Switzerland | Ligand Target Identification |
| Ergomed | Krakow, Poland | Clinical Research |
| Agilent | Shanghai, China | High-Throughput Screening Equipment, Imaging instruments |
| Metabolys | , | Website under construction Mar 2020 - Mar 2021 |
| Antibe Therapeutics | , | Acquired by Taro Pharmaceuticals, Mar 2025 |
| Seraph Biosciences | Detroit, MI | POC Pathogen Detection |
| Orsenix | , | Website down May 2021 - Dec 2021 |
| Cortendo | , | Renamed Strongbridge Biopharma Sep 2015 |
| Tethys Bioscience | , | Shut Down, late 2013 |
| Accutome | , | Now part of Keeler |
| BioNevia Pharmaceuticals | , | Website taken over May 2020 |
| CESCA Therapeutics | , | Renamed ThermoGenesis; Formed when TotipotentRX and thermogenesis merged Jul 2013 |
| STAAR Surgical | Lake Forest, CA | Implantable Lenses |
| Reprieve Cardiovascular | Milford, MA | Heart Failure Fluid Management |
| Therasentient Biopharma | , | Website down Feb 2021 - Sep 2021 |
| BVI Medical | Waltham, MA | Ophthalmic devices |
| Ichor Therapeutics | , | Renamed Ichor Life Sciences |
| Axenis | , | Acquired by genOway, Sep 2018 |
| Humacyte | Durham, NC | Bioengineered Vessels |
| Remelux Biopharmaceuticals | , | Website gone Nov 2015 |
| Charles River Laboratories | East Lothian, UK | Research Animal Models and Preclinical Research |
| DelMar Pharmaceuticals | , | Renamed Kintara Therapeutics after merging with Adgero, Aug 2020 |
| , | Acquired by Biomarin, Jul 2025, $270M | |
| Obvius Robotics | Sunrise, FL | Vascular Access Device |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| PuriCore | , | Changed name to Realm Therapeutics, Dec 2016 |
| TECLens | Stamford, CT | Quantitative Cross-Linking to gently reshape the cornea |
| Charles River Laboratories | Bengaluru, India | Research Animal Models and Preclinical Research |
| Virna Therapeutics | , | Website down Dec 2023; Not registered in MA, Aug 2022 |
| Cipher Surgical | Chantilly, VA | Surgical Vision Platform |
| Diverse Genomics | , | Website gone Jul 2020 |
| Quansys Biosciences | Logan, UT | Multiplexed ELISA, Imaging Software |
| Baylis Medical Technologies | Mississauga, ON | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Propharma Partners | , | Website down Sep 2023 - Mar 2024 |
| ConcertAI | Cambridge, MA | Oncology Contract Research |
| Scopio Labs | Tel Aviv, Israel | Full-field Imaging |
| , | No news 2020 - Nov 2025 | |
| Sonkei Pharmaceuticals | , | Merged with Cyrenaic Pharmaceuticals in 2013 to form Minerva Neurosciences |
| Editas Medicine | Cambridge, MA | Genome Editing Therapies (CRISPR) |
| Charles River Laboratories | Erkrath, Germany | Research Animal Models and Preclinical Research |
| NuVascular Technologies | , | Shut down Nov 2021 |
| Vicore Pharma | Stockholm, Sweden | Small Molecule |
| Seqens CDMO North America | , | Building exploded May 2023; Renamed Seqens CDMO North America; Acquired by Novacap, Jul 2018 |
| Kinex Pharmaceuticals | , | Changed name to Athenex |
| Coeptis | , | |
| Advarra | Columbia, MD | Regulatory Consulting |
| Adva Biotechnology | Ahihud, Israel | Biologics Manufacturing Platform |
| Syantra | Calgary, AB | Breast cancer blood test |
| Tara Biosystems | , | Acquired by Valo Health, Apr 2022 |
| Innovative Pulmonary Solutions | , | Renamed Nuvaira |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Equaly | Louvain-la-Neuve, Belgium | Biologics & Immunotherapy Improvement |
| , | Shutdown Oct 2025 | |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Enara Bio | Oxford, UK | Dark Antigens to deliver targeted off-the-shelf cancer vaccines and other immunotherapies for treating and preventing cancer |
| Noventia Pharma | , | No news 2011 - Mar 2025 |
| Neurosoft Bioelectronics | Geneva, Switzerland | Materials for Brain-computer interfaces |
| Orchestra BioMed | New Hope, PA | Medical devices |
| Purigen Biosystems | , | Acquired by Bionano Genomics, Nov 2022 |
| Pharmasynth | , | Renamed LuinaBio, 2016 |
| Statera Biopharma | , | Bankrupt Jun 2022; went public via Reverse Merger with Cleveland BioLabs, Oct 2020 |
| PathoGenesis | , | Acquired by Chiron, 2000, $600M |
| Physiogenex | Escalquens, France | Preclinical CRO & Consulting |
| Retrophin | , | Renamed Travere Therapeutics, Nov 2020 |
| Stratos Genomics | , | Acquired by Roche, May 2020 |
| Cognosetta | , | Gone 2021 |
| Advaned Viral Research | , | Shut down 2009 |
| Tailor Bio | Cambridge, UK | Cancer Treatments |
| Vencerx Therapeutics | , | Website gone Feb 2019, No employees Apr 2019 |
| Scantox | Lille Skensved, Denmark | Discovery, Toxicology, Regulatory, Analytical Services |
| Lab7 | , | Changed name to LV Informatics, May 2018 |
| DiaKine Therapeutics | , | Acquired by Islet Sciences Mar 2012 |
| Santen | Munich, Germany | Regulatory & Scientific Marketing |
| Cytovant Sciences | , | Website down Jul 2022 - Nov 2022 after ending development of main product; Sinovant/Roivant offshoot |
| Immune Control | , | Merged with Arginetix to become Corridor Pharmaceuticals, Jun 2010 |
| Basilard BioTech | Temecula, CA | Gene Delivery Platform |
| Vantage Medtech | Lenexa, KS | Medical Device Design & Development |
| SIRPant Immunotherapeutics | , | Renamed BobcatBio, Jan 2025 |
| ASIT Biotech | , | Renamed DMS Imaging |
| Amgen | South SF, CA | Small Molecules, Biologics |
| Crown Bioscience | Taicang, China | Drug Development |
| CardioKinetix | , | Website down, Apr-Dec 2018 |
| Medmix | Baar, Switzerland | High-precision delivery devices and fluid mixing |
| Sun Pharm Corp | , | Acquired by Geltex Pharmaceuticals |
| AdeTherapeutics | , | Strategic Options, Jul 2012; Previously had a website, none as of Feb 2016 |
| Hovione | Hong Kong, China | Contract Manufacturing |
| Enterome | Paris, France | Microbiome-related diseases, diagnostics |
| Gamma Diagnostics | Portland, OR | ELISA method for the detection and assessment of Gamma Prime Fibrinogen |
| First Tracks Biotherapeutics | San Diego, CA | Antibody Therapeutics |
| PixarBio | , | Evicted from Medford, MA HQ for failure to pay rent. CEO being prosecuted by SEC 2018 |
| AustinPx | Georgetown, TX | Contract development and manufacturing |
| ExonanoRNA | , | Website down Apr 2024 - Aug 2024 |
| BTB Therapeutics | Escondido, CA | Non-opioid therapies and novel RNA splicing modifiers |
| Ophiomics | Lisboa, Portugal | Genetic and genomic diagnostic and prognostic tests for liver cancer |
| Chantilly BioPharma | , | Bankrupt Jun 2014 |
| YMC Process Technologies | Koyoto , Japan | Purification Technology |
| Corden BioChem | Frankfurt am Main, Germany | Biotech CDMO |
| ISTO Technologies | , | Merged with Arteriocyte Medical Systems to become ISTO Biologics, Oct 2016 |
| Pathfinder Cell Therapy | , | Gone 2016 |
| , | Dissolved, Apr 2024 | |
| Evinco Therapeutics | , | Immune therapies for Alzheimer's and neuroimmune |
| Acureon Pharmaceuticals | , | Closed 2008 |
| FORGE Life Science | , | Renamed Evrys Bio, Aug 2019 |
| Velquest | , | Bought by Accelrys Jan 2012 |
| DLK Medical Technologies | Dallas, TX | OTC |
| apceth | , | Acquired by Hitachi Chemical, Apr 2019 |
| CMX Research | Oakville, ON | Clinical Trial Services / Management |
| Biophytis | Paris, France | Therapies for aging diseases |
| Rasna Therapeutics | , | Dissolved, Feb 2021 |
| Artemisia BioMedical | , | Closed 2016, CEO confirmed they decided to shut down |
| Immune Design | , | Bought by Merck, Feb 2019, $300M |
| Genome Therapeutics | , | Renamed Oscient Pharmaceuticals, May 2004 |
| Erbe | Tübingen , Germany | Surgical Systems |
| Immunophotonics | St. Louis, MO | Autologous cancer vaccine |
| InProTher | , | Renamed Hervolution Therapeutics, Sep 2023 |
| GSK | Barnard Castle, UK | Small Molecules, Vaccines, Biologics |
| Pharmanovia | London, UK | Acquisition of Drugs |
| ValueGene | , | Acquired by Integrated DNA Technologies, Jun 2016 |
| Neuraptive Therapeutics | Chesterbrook, PA | Therapies for nerve repairs |
| Humanyx | , | No website, Seems gone |
| Cellendes | Reutlingen, Germany | 3D Cell Culture |
| |
Springfield, MO | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| GammaDelta Therapeutics | , | Acquired by Takeda, Oct 2021 |
| Arc Therapeutics | , | Renamed Incyclix Bio |
| LexaMed | Toledo, OH | Life Science Consulting |
| January Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| ESCAPE Bio | , | Shut Down Dec 2022 |
| Carcinotech | Roslin, UK | 3D printed tumors |
| Aelian Biotechnology | , | Renamed Myllia, Apr 2022 |
| Axikin Pharmaceuticals | , | Closed per Google |
| Eos Neuroscience | , | Business inactive in CA, website not updated since 2010, Preclinical stage 2010-2020 |
| Sensydia | Los Angeles, CA | Cardiac Function Measurement |
| , | Acquired by Leinco Technologies, Sep 2024 | |
| Advanced Bionics | Valencia, CA | Cochlear Implants |
| Vero Biotech | Atlanta, GA | Nitric Oxide Generation & Delivery |
| Protez Pharma | , | Bought by Novartis 2008, Closed 2010 |
| Cytodiagnostics | Burlington, ON | Nanoparticle Reagents, Rapid Test Development Kits, Diagnostic Assay Components |
| WuXi Apptec | San Diego, CA | All types of contract work for small molecules, devices |
| Inspiration Biopharmaceuticals | , | Bankrupt/Sold Hemophilia Assets, Site not active as of 01-20-14 |
| PeproTech | , | Acquired by Thermo Fisher, Jan 2022, $1.85B |
| Medi-Lynx Cardiac Monitoring | , | Website down Feb 2024 - Jul 2024 |
| Bioemtech | Athens, Greece | Preclinical Services, Scanners, Software |
| FemTherapeutics | Montreal, QC | Personalized pessaries |
| Vicarius Pharma | , | Website gone, no info Oct 2021 |
| ZimVie | Parsippany, NJ | Dental Implants; Allografts |
| Cortice Biosciences | , | No real employees, no website Nov 2019 - Dec 2020, CEO gone |
| Viramed Biotech | , | Cannot confirm active Mar 2025 |
| Ohana Biosciences | , | Voluntarily winding down Apr 2021; fka VL34 |
| Axsendo Clinical Research | Phoenix, AZ | Clinical Research Network |
| Syneos Health | Princeton, NJ | Clinical Development |
| Forward Clinical Trials | , | Acquired by Cenexel, Aug 2021 |
| Aprogen | Gyeonggi, Korea | Antibodies, biosimilars, generics |
| AllCells | Alameda, CA | Cytokines, Stem Cells, Media, etc. |
| Alkami Biosystems | , | Dissolved, Pre-2005 |
| Apieron | , | Shut down, May 2010 |
| Lungpacer Medical | Vancouver, BC | Diaphragm Pacing Therapy |
| Avexa | , | Renamed Novita Healthcare |
| Triad Isotopes | , | Acquired by Jubilant, Jun 2019 |
| Quinta-Analytica | Prague, Czech Republic | Contract Research, Services |
| AGTC | , | Acquired by Syncona, Dec 2022, $23.5M + $50M milestones |
| Proteo Biotech | , | Renamed Tiakis Biotech, Sep 2022 |
| NAMSA | Irvine, CA | Medical Research Organization - Medical Devices |
| Unimed Pharmaceuticals Inc | , | Acquired by Solvay Jun 1999 |
| OnCore Biopharma | , | Merged with Tekmira, Jan 2015 |
| Top Canada Pharmaceuticals | , | Website gone, Apr 2019 |
| RespiVert | , | Acquired by Centocor Jun 2010 |
| Medical Advancement Through Clinical Research | , | Website down Oct 2023 - Mar 2024 |
| Akadeum Life Sciences | Ann Arbor, MI | Cell sorting with microbubbles |
| Indexus Biomedical | , | Shut down 2018 |
| VectorBuilder | Neu-Isenburg, Germany | Recombinant Vectors & Viruses |
| Axplora | Mourenx, France | API manufacturing |
| , | Bankrupt, ceased operations Mar 2026 | |
| XDx | , | Changed name to CareDx |
| GenPro Genome Profiling | , | Website down Mar 2023 - Sep 2023 |
| AbelZeta Pharma | Rockville, MD | Cell Therapy |
| Amolyt Pharma | , | Acquired by AstraZeneca, Jul 2024, $800M + $250M milestones |
| Tribute Pharmaceuticals | , | Merged with Pozen, Dec 2015, became Aralez Pharmaceuticals |
| Glycotope | , | Assets acquired by Pentixapharm Jul 2024; aka Glycotope Biotechnology |
| Pristine Surgical | Manchester, NH | Single use digital imaging platform |
| Abridge | Pittsburgh, PA | AI to convert a patient-clinician conversation into a structured clinical note |
| Intercept Pharmaceuticals | Morristown, NJ | Small Molecules |
| Genea Biocells | , | Website down Jan 2019-Feb 2019 |
| CerSci Therapeutics | , | Acquired by Acadia Pharmaceutical, Aug 2020, $52.5M stock |
| Origene | Rockville, MD | Human cDNA Library, Monoclonal Antibodies |
| Amlogenyx | Novato, CA | Gene Therapy for Alzheimer's |
| Aluda Pharmaceuticals | Menlo Park, CA | Small Molecules |
| Ora Clinical | , | Website still has pandemic verbiage at top, not registered in MA, Mar 2024 |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Admune Therapeutics | , | Acquired by Novartis, Oct 2015 |
| Piramal | Mahad, India | CDMO |
| Tanabe Research | , | Website down Apr 2023 - Sep 2023 |
| Synimmune | , | Acquired by Veraxa Biotech, Jan 2024 |
| , | Renamed Stelexis BioSciences | |
| |
Espoo, Finland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Bridge Pharma | , | Website being updating from 2016-2018 |
| Anodyne Medical Device | , | Renamed Tridien Medical, May 2010 |
| AgenDx Biosciences | , | Website gone Mar 2022 - Jul 2022 |
| Asieris Pharmaceuticals | Radnor, PA | Small Molecules, Drug-Device Comvo Product |
| Veran Medical Technologies | , | Acquired by Olympus, Dec 2020, $340M |
| Arda Therapeutics | San Carlos, CA | Pathogenic Cell Depletion via ADCs |
| Mast Group | Liverpool, UK | Cell Systems, Reagents, Assays |
| HighRes Biosolutions | Beverly, MA | Lab Automation Instruments |
| Sana Health | Louisville, CO | Neuromodulation for Pain Relief |
| , | Renamed LeonaBio, Jan 2026 | |
| Longevica Pharmaceuticals | , | No info, but believed inactive |
| Omnitura | , | Website gone Jan 2022 |
| Aria Neurosciences | , | Blog spam website now, Mar 2021 |
| Absynth Biologics | , | Website Gone Jan 2019 |
| Ivivi Orthopedic Health | , | Changed name to Amp Orthopedics, Nov 2011 |
| Pharmaron | Xi'an, China | R&D Services |
| MicroDose Technologies | , | Renamed MicroDose Therapeutx? |
| Hal Allergy | Leiden, Netherlands | Allergy Treatments |
| Dermelix Biotherapeutics | , | Website down Jul 2021 - Jan 2022 |
| Affinivax | , | Acquired by GSK, Aug 2022 |
| EndoRobotics | Seoul, Korea | Non-invasive Endoscopy |
| Human Metabolome Technologies | Tokyo, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Persomics | , | Gone 2019 |
| Orthopedic Precision Instruments | , | Shut down Feb 2008 |
| Cellular Genomics | , | Renamed CGI Pharmaceuticals |
| ResMed | San Diego, CA | Medical Devices |
| Imagenomix | New York, NY | Cancer Diagnostics Imaging |
| Tempest Therapeutics | Brisbane, CA | Small Molecules for Immuno-Oncology |
| Ardelyx | Newark, CA | Gastrointestinal Therapeutics |
| Avanti Biosciences | , | No business filings Jan 2020 - Nov 2023 |
| Molecular Templates | , | Liquidating, Oct 2024; Merged into Threshold Pharmaceuticals, Aug 2017, company took Molecular Templates name |
| Station X | , | Website Gone Mar 2018 |
| NovelMed Therapeutics | Cleveland, OH | Monoclonal Antibodies |
| Sevengenes | , | Website gone Aug 2019 - Dec 2020, not filing business docs |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| Viant Medical | Tijuana, Mexico | Contract Medical Devices |
| XiltriX | San Diego, CA | Lab Monitoring Service |
| Enable Life Sciences | Worcester, MA | Pharma Consulting |
| Beckman-Coulter | Indianapolis, IN | Lab Machines |
| NanoOncology | , | Website not active, redirects to another inactive Website as of Nov 2016. No info |
| Keymed Biosciences | Chengdu, China | Monoclonal Antibodies, ADCs, Bispecifics |
| Sunbird Bio | Cambridge, MA | Protein-based Diagnostics |
| MilliporeSigma | Schaffhausen, Switzerland | Small Molecules |
| , | Acquired by Instem, Jul 2025 | |
| Volastra Therapeutics | New York, NY | Therapies for the treatment of metastatic cancers |
| Exscientia | , | Acquired by Recursion Pharmaceuticals, Nov 2024 |
| BiVACOR | Houston, TX | Heart replacement |
| BioCardia | Sunnyvale, CA | Personalized marrow-derived cell therapy |
| Zymedi | Incheon, Korea | Noncatalytic regulatory roles of aminoacyl-tRNA synthetases as novel therapeutic targets |
| Wockhardt | Mumbai, India | Generics, Contract Manufacturing |
| Gem Pharmaceuticals | , | Sold primary asset to Monopar Therapeutics, Nov 2017 |
| Novotech | Melbourne, Australia | Clinical Research |
| Bioagilytix | Boston, MA | Bioanalytical services, immunoassays, cell-based assays |
| Recordati | Aprilia, Italy | Small Molecule Manufacturing |
| Naobios | Saint-Herblain, France | CDMO specialized in viral production |
| Exactech | Gainesville, FL | Medical Implants |
| Pfizer | Pearl River, NY | Small Molecules, Vaccines, Biologics |
| Trieza Therapeutics | , | New Dec 2016, use trieza.com for email, no website Sep 2018 - May 2023 |
| Froptix | , | Merged with eXegenics and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| BioSpring | La Jolla, CA | Manufacturing & Analytical Services |
| Caidya | Shanghai, China | Clinical Research Organization |
| FOMAT Medical Research | Oxnard, CA | Clinical Site Network |
| Pivotal Therapeutics | , | Seems to have gone out of business, 2021 |
| Sotera Health | Broadview Heights, OH | Sterilization, Lab Testing |
| HistoWiz | Brookyln, NY | Automated Histopathology |
| Cvie Therapeutics | , | Merged with Windtree Labs Jan 2019 |
| Abbott | Irving, TX | Devices |
| Theriva Biologics | Rockville, MD | Oncolytic Virus Therapies |
| Antera Therapeutics | , | Pivoted to medical food (and renamed Adeo Health Science) after FDA warning letter about selling an unlicensed biologic |
| Hovione | Lisbon, Portugal | Contract Manufacturing |
| CheckMab | Milan, Italy | Therapeutic Monoclonal Antibodies |
| MedCision | , | Assets bought by MedCision, May 2018 |
| |
Farmingdale, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Zeltiq | , | Bought by Allergan, Feb 2017, $2.4B |
| ZimVie | Palm Beach Gardens, FL | Dental Implants; Allografts |
| Madrigal Pharmaceuticals | West Conshohocken, PA | Small Molecules |
| Nina Biotherapeutics | , | Gone, after 2015 |
| StemCellLife | , | Website Gone Jan 2019 - Dec 2019 |
| Johnson and Johnson Innovative Medicine | San Diego, CA | Small Molecules, Biologics |
| Abpro | Burlington, MA | Antibodies |
| BLA Regulatory | Gaithersburg, MD | Providing end-to-end tailored regulatory strategy and execution services from INDs to NDA/BLAs |
| APRINOIA Therapeutics | Hong Kong, China | Alzheimer's Treatments and Diagnostics |
| Amneal Pharmaceuticals | Brookhaven, NY | Generic Small Molecules |
| Cerexa | , | Acquired by Forest Labs Dec 2006 |
| Inotiv | West Lafayette, IN | Contract lab services, Scientific Instruments |
| , | Subsumed into Synoptics | |
| Alacrita | London, UK | Life science consulting firm offering strategic, clinical & business development support to pharma & biotech |
| ProFibrix | , | Bought by The Medicines Company, Aug 2013, $90M + $140 milestones |
| Blue Earth Diagnostics | Oxford, UK | Molecular Imaging Technologies |
| rMark Bio | , | Acquired by Within3, Apr 2021 |
| Tunnell Consulting | Berwyn, PA | Consulting |
| , | Acquired by Qiagen, May 2025, $70M + $10M milestones | |
| Clinical Research Advantage | , | Bought by Radiant Research, Nov 2012 |
| Duchesnay USA | Rosemont, PA | OB/GYN Products |
| SPD Swiss Precision Diagnostics | Bedford, UK | Consumer Diagnostics |
| , | Website down Dec 2025 - Apr 2026; Liquidation Sep 2025 | |
| , | Merged with Endo, Nov 2025 to become Keenova/Par Health | |
| Syvento BioTech | Skawina, Poland | Lipid-based nanocarriers and LNP technology |
| TCI Peptide Therapeutics | , | Website down May 2021 - Sep 2021 |
| Vrata Therapeutics | Cambridge, | |
| Regenity Biosciences | Paramus, NJ | Extracellular matrices for tissue and organ repair and regeneration |
| Ablaze Pharmaceuticals | , | Shut down Dec 2024 |
| Synaptive Medical | Toronto, ON | Digital Microscope, MRI, Surgery models, Data Organization Software |
| LiNA MEDICAL | Norcross, GA | Minimally invasive gynecology |
| Optim Associates | , | Website under construction Mar 2022 - Sep 2022; Residential Address, Oct 2021 |
| 199 Biotechnologies | London, UK | Combating disease and aging by reversing age-related cellular changes through epigenetic reprogramming |
| AZTherapies | , | Website down Sep 2023 - Mar 2024 |
| Nuvation Bio | San Francisco, CA | Oncology Treatments |
| , | Pivoted to crypto Jan 2026 | |
| QuantRx Biomedical | , | Shell company |
| Elpis Biomed | , | Renamed bit bio, Oct 2019 |
| Ophthotech | , | Renamed Iveric Bio, Apr 2019 |
| Mela Science | , | Renamed Strata Skin Sciences, Dec 2015 |
| tte laboratories | , | Acquired by Transcat |
| Inhibrx Biosciences | La Jolla, CA | Antibodies, Fusion Proteins |
| Cochlear | Lone Tree, CO | Cochlear Implants |
| Cohortias | Mexico City, Mexico | Full-Service CRO |
| LipimetiX Development | , | Website gone, Jan 2020 |
| Think Bioscience | Boulder, CO | Microbial systems to guide the development of small-molecule drugs |
| Meribel Pharma Group | Erstein, France | Contract Manufacturing |
| CStone Pharmaceuticals | Suzhou, China | Immuno-Oncology |
| UniTaq Bio | , | Website down Sep 2020; No one works at this fulltime |
| , | Shut down May 2026, assets to Innoviva | |
| GL Chemtec | Oakville, ON | Discovery-phase contract research |
| CONMED | Lithia Springs, GA | Surgical, Medical Devices |
| Patheon | Mississauga, ON | Contract Manufacturing and Development |
| Canfield Scientific | Dural, Australia | Medical Imaging, Clinical Research Services |
| Genten Therapeutics | , | Business filings late Feb 2024; No Info/Website, Apr 2019 - Feb 2024 |
| Experimentica | Vilnius, Lithuania | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| Apama Medical | , | Acquired by Boston Scientific, Oct 2017, $175M + $125 Milestones |
| Boston Microfluidics | , | Renamed Weavr Health, Apr 2021 |
| Liquid Biotech | , | Website down Dec 2022 - Apr 2023 |
| Quanam Medical | , | Acquired by Boston Scientific, Apr 2001, $8M |
| Makana Therapeutics | , | Merged into Recombinetics, Oct 2020 |
| Medeloop | San Francisco, CA | AI Clinical Research Platform |
| Rockland Immunochemicals | Limerick, PA | Antibodies & Assays |
| Kalbe | Jakarta, Indonesia | Small Molecules |
| Bristol Myers Squibb | San Diego, CA | Small Molecules, Biologics |
| Cell Therapy Group | , | Rights to drug sold to Daiichi, May 2016; Guy who left years ago still listed as managing director |
| Pervasis Therapeutics | , | Bought by Shire 2012 |
| Immatics Biotechnologies | Munich, Germany | Personalized T-cell Directed Immunotherapies |
| Median Technologies | Shanghai, China | Imaging Phenomics |
| Viron Therapeutics | , | Renamed Porosome Therapeutics, Aug 2023 |
| NeoDiagnostix | , | Website Down Feb 2025 |
| Jixing Pharmaceuticals | , | Renamed Corxel Bio, Oct 2024 |
| Hotspur Technologies | , | Acquired by Teleflex, Jul 2012 |
| Advenchen Laboratories | Moorpark, CA | Small Molecules |
| BEBIG Medical | Mount Vernon, NY | Radiation Therapy Products |
| RheoSense | San Ramon, CA | Viscometers |
| Vitalea Science | , | Acquired by Eckert & Ziegler, Sep 2012, now called Eckert & Ziegler Vitalea Science |
| Byonyks Medical Devices | Lahore, Pakistan | Home-based, bloodless peritoneal dialysis machines |
| Omega Medical Imaging | Sanford, FL | AI-Guided Imaging Solutions |
| ProPharma Group | San Diego, CA | Consulting |
| Deepcell | Menlo Park, CA | Genetic Tests |
| NorthLinks Bio | , | |
| Pantec Biosolutions | Ruggell, Liechtenstein | Various drug delivery technologies |
| Eleva | Freiburg, Germany | Moss-derived Drug Discovery Platform |
| Biome360 | , | Website down Jan 2021 - Apr 2021 |
| Veloce BioPharma | , | Website down Oct 2021 - Mar 2022 |
| Helios Cardio | Weston, MA | Development of regenerative biologic matrices |
| Chiesi | Parma, Italy | Small Molecules, Biologics, Orphan Drugs |
| DNASTAR | Madison, WI | Molecular Biology Software |
| ACell | , | Acquired by Integra LifeSciences, Jan 2021, $300M |
| Avilar Therapeutics | Waltham, MA | Extracellular Targeted Protein Degradation |
| CelineBio | , | Website down Jun 2024 - Nov 2024; fka Celine Therapeutics |
| Pledge Therapeutics | Leuven, Belgium | Antivirals, Antiinfectives, Immuno-Oncology |
| ImmunoBiology | , | Website down Dec 2022 - Apr 2023 |
| Bilim Pharmaceuticals | Istanbul, Turkey | Turkish pharmaceutical with >150 products in 17 areas and R&D |
| Capnia | , | Changed name to Soleno Therapeutics, May 2017 |
| Regulus Pharmaceutical Consulting | , | Acquired by Clinipace |
| Cresilon | Brooklyn, NY | Hemostatic Gel |
| Ad Astra Diagnostics | Morrisville, NC | POC White Blood Cell Count |
| Fuji Yakuhin | Saitama, Japan | Generics |
| Apini Therapeutics | , | |
| Charles River Laboratories | Senneville, QC | Research Animal Models and Preclinical Research |
| Activus Pharma | , | Acquired by Sosei Group, Jun 2010, $5.6M |
| SpiroChem | , | Website down Apr 2024 - Aug 2024 |
| Volumina Medical | Epalinges, Switzerland | Innovative biomaterials for regenerative medicine |
| Monosol Rx | , | Changed name to Aquestive Therapeutics, Nov 2017 |
| Mammoth Biosciences | Brisbane, CA | CRISPR, Gene-Editing Therapies |
| UBC | Morgantown, WV | Biopharmaceutical Consulting & Services |
| BioGenex | Hyderabad, India | Cellular & Molecular Diagnostics |
| Arkuda Therapeutics | , | Assets Acquired by Johnson & Johnson, Jan 2025 |
| MicroStem | , | Gone Jun 2017 |
| Clinical Trial Network | , | Website Gone, Sep 2017 |
| Impel Pharmaceuticals | , | Bankrupt, sold to investors, Feb 2024 |
| Kronos Bio | , | Acquired by Concentra Biosciences, Jun 2025 |
| DiaVax Biosciences | , | Renamed Helocyte |
| Incyte | Wilmington, DE | Small Molecules |
| SynConnection | , | Website down Nov 2023 - Dec 2023 |
| Hawthorn Pharmaceuticals | , | Acquired by Pernix Jan 2012 |
| Estetra | , | Acquired by Richter, Jun 2024 |
| Hinova Pharmaceuticals | Chengdu, China | Small Molecules |
| Promis Diagnostics | Irvine, CA | Diagnostics |
| Trinity Pharmaceuticals | , | Acquired by Chiesi Farmaceutici, 1999 |
| Imperial Life Sciences | Gurgaon , India | Genomic Analysis |
| LSI Solutions | Victor , NY | Minimally invasive surgical devices |
| Magnum Therapeutics | , | Acquired by Introgen Therapeutics, Oct 2004 |
| AM Biotech | , | Renamed Raptamer Discovery Group |
| Yourgene Health | Manchester, UK | Prenatal Screening |
| DesigneRx Pharmaceuticals | , | Website down Feb 2021 - Jun 2021; Pivoted from proprietary drugs to contract mfg |
| Rakuten Medical | Tokyo, Japan | Antibody conjugates for cancer |
| VascularStrategies | Plymouth Meeting, PA | Assays and research services for preclinical and clinical drug development |
| Versameb | Basel, Switzerland | RNA Therapeutics |
| Adaptive Biotechnologies | Seattle, WA | T Cell Receptor Analysis |
| Apath | , | No website update since 2014, Feb 2023 |
| medPhoton | Salzburg, Austria | Medical imaging, Robotics |
| Xen Biofluidx | , | Website down Dec 2022 - Apr 2023 |
| Orphalan | Birkirkara , Malta | Small molecule for Wilson's disease |
| Bausch & Lomb | , | Acquired by Valeant, rebranded as Bausch Health |
| Cam Med | , | Renamed Qlibrium |
| Redpoint Bio | , | Inactive |
| Nucryst | , | Bought by Smith & Nephew |
| AOP Orphan Diseases | Warsaw, Poland | Orphan disease treatments |
| LAT Pharma | , | Acquired by NanoAntibiotics, Apr 2016 |
| Novasecta | London, UK | Pharma Consultancy |
| PharmaCell | , | Acquired by Lonza, May 2017 |
| IdentifySensors | Shaker Heights, OH | Infection & Biomarker Detection |
| Veristat | Morrisville, NC | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| XCell Biologix | , | Renamed Bioheal Therapeutics, Jan 2023 |
| BioHybrid Solutions | , | Renamed Myris Therapeutics, Feb 2024 |
| TherimuneX Pharmaceuticals | , | No website Nov 2019 - Nov 2023 |
| C2 Therapeutics | , | Acquired by Pentax Medical, Jan 2017 |
| Tecan | Männedorf, Switzerland | Lab Instruments, Automation |
| Biocodex | Gentilly, France | Microbiota Treatments |
| AKESOgen | , | Acquired by Tempus, Dec 2019 |
| Rezo Therapeutics | San Francisco, CA | |
| Neurotronik | , | Most employees moved to InnerPulse |
| Cleerly | Denver, CO | AI-driven Image Analysis for Coronary Health |
| Base Genomics | , | Acquired by Exact Sciences, Oct 2020 |
| PhotoBiotics | , | Renamed Antikor Biopharma |
| Vertex | Boston, MA | Small Molecules, Gene Editing, Cell Therapy |
| , | Renamed Ladder Bio, Nov 2025 | |
| Anji Pharmaceuticals | , | Shut down Aug 2024 |
| Aset Therapeutics | , | No website, no info Jan 2019 - May 2023 |
| Crinetics Pharmaceuticals | San Diego, CA | Small Molecules |
| Novoclem Pharmaceuticals | , | Renamed Vast Therapeutics |
| Virchow Biotech | , | Website down Nov 2022 - Apr 2023 |
| Synbiotics | , | Acquired by Pfizer Dec 2010. Included in Zoetis spinout |
| Krenitsky Pharmaceuticals | , | Website gone 2-27-15, company is old |
| ABL Europe | , | Acquired by Oxford Biomedica, Jan 2024; Website down Jan 2021 - May 2021 |
| Centaur Biopharmaceutical Services | , | Website down May 2022 - Oct 2022 |
| Stratify Genomics | , | Website down Nov 2022 - Mar 2023 |
| Catalyst OrthoScience | Naples, FL | Shoulder Arthroplasty |
| Chipscreen Biosciences | Shenzhen, China | Cancer therapies |
| Factory CRO | , | Became Aviana Apr 2020, post-merger with several companies |
| HLT Medical | , | Website down Jan 2023 - Sep 2023 |
| eZono | Jena, Germany | Virtual Needle Guidance |
| Oncothyreon | , | Changed name to Cascadian Therapeutics, Jun 2016 |
| Renew Biopharma | , | Business filings late Feb 2023; No news 2020 - Dec 2024 |
| Therabron Therapeutics | , | Bought by Brace Pharma Capital Jan 2015 |
| |
Starnberg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Bio-quant | , | Sold by Apricus to BioTox Sciences Jul 2011 |
| Pfizer | Warsaw, Poland | Small Molecules, Biologics, Vaccines |
| Absolute Biotech | , | Merged with Vector Laboratories, May 2024 |
| , | Crypto Pivot, Oct 2025 | |
| Bioniz Therapeutics | , | Acquired by Equillium, Feb 2022, $329M |
| Chugai Pharma | Yokohama, Japan | Small Molecules |
| Multimeric Biotechnologies | , | Comically outdated website, Nov 2019, no employees on LinkedIn |
| Biomedal | Sevilla, Spain | Molecular Biology, Protein Products, Equipment |
| MB Therapeutics | Montpellier, France | 3D printed personalized medicines |
| Simulations Plus | Research Triangle Park, NC | Modeling and simulation software and consulting services |
| BiomerTechnology | , | Ancient website, never registered in CA |
| Pathens | , | Website hijacked Sep 2020 |
| Cutanos | Vienna, Austria | Cell Targeting Delivery System |
| , | Website down Oct 2025 - Feb 2026 | |
| Meribel Pharma Group | Provence, France | Contract Manufacturing |
| Berthold Technologies | Bad Wildbad, Germany | Life Science Instruments |
| RadioTherapeutics | , | Acquired by Boston Scientific, Nov 2001, $150M |
| Orthoscan | Scottsdale, AZ | Orthopedic Imaging |
| HackScience | , | Renamed Cytera, Nov 2018 |
| Corlieve Therapeutics | , | Acquired by uniQure, Jun 2021, $55M + $240M milestones |
| Vigonvita | Suzhou, China | Small Molecule Drugs, Generics |
| DigiSight | , | Renamed Verana Health, Jul 2018 |
| CPEX Pharmaceuticals | , | Bought by FCB I Holdings, Apr 2011. Not sure what they did with the company/assets. Originally was a spinout from Bentley Pharmaceuticals when it was acquired by Teva in 2008 |
| Vital Metrix | , | Website down Jul 2023 - Dec 2023 |
| SynHelix | , | Website Down Feb 2025 - Jul 2025; Acquired by Univercells, Jan 2022 |
| MoMelan Technologies | , | Acquired by Kinetic Concepts, Nov 2012 |
| Microchips Biotech | , | Acquired by Dare Bioscience Nov 2019; fka microCHIPS inc |
| Patheon | High Point, NC | Contract Manufacturing and Development |
| Rapid Medical | Yokneam, Israel | Clot retriever, Adjustable Mesh |
| Kura Biotech | Peurto Varas, Chile | Enzymatic reagents for sample prep, including recombinant enzymes for toxicology, genomics and proteomics applications |
| Candel Therapeutics | Needham, MA | Oncolytic Viral Immunotherapies for Cancer |
| Seqera | Barcelona, Spain | Bioinformatics Platform |
| Large Scale Biology | , | Shut Down |
| iGenomX | , | Acquired by Twist Biosciences, Jun 2021 |
| Ansata Therapeutics | , | Out of business 2007 |
| Johnson & Johnson MedTech | Warsaw, IN | Medical Devices |
| leadXpro | Villigen, Switzerland | Contract Drug Discovery |
| Veeda Lifesciences | Ahmedabad, India | Preclinical & Clinical Research |
| SeylanMED | , | Acquired by DermBiont, Oct 2020 |
| PharmaSphere | , | Acquired by Marijuna company, Nov 2011 |
| AMUR Pharmaceuticals | , | Bought by SuperGen |
| H2O Clinical | , | Merged with Pharma Start, Aug 2016 to become Firma Clinical Research |
| Owkin | New York, NY | AI for Medical Research |
| Worthington Biochemical | Lakewood, NJ | Enzymes |
| CBCC Global Research | Ahmedabad, India | Clinical Services |
| Pharmasol | , | Website down Feb 2025 - Jul 2025 |
| Larkspur Biosciences | Cambridge, MA | Cancer Immunotherapies |
| Grove Instruments | , | Shut Down June 2017 |
| , | Acquired by Kite, Aug 2025 | |
| Keenova | Bridgewater, NJ | Small Molecules |
| Novex Clinical Research | , | Acquired by BTC Network, Aug 2016 |
| Pinnacle Medicines | Shanghai, China | Oral Peptides |
| Cristers | Suresnes, France | Generics |
| Sigmapharm Laboratories | Bensalem , PA | Formulation of generics |
| Veeva Systems | São Paulo, Brazil | Life Science Software |
| Novacyt | Vélizy-Villacoublay, France | Diagnostics |
| Orchid Orthopedic Solutions | Santa Ana, CA | Contract Medical Device Work |
| Unimedic | , | Website down Mar 2020 - Jul 2020 |
| Clinbiometrics | , | Renamed Thrive Informatix, Jan 2024 |
| Menarini | L'Aquila, Italy | Small Molecules |
| , | Website down Dec 2025 - Jun 2026 | |
| Spectrum Vascular | White Plains, NY | Vascular access devices with antimicrobial protection and thrombus reduction technologies |
| SeaBeLife Biotech | Roscoff, France | Necroptosis and ferroptosis fighting molecules |
| DifGen Pharmaceuticals | Miramar, FL | APIs, Formulated Generics |
| Kerecis | Arlington, VA | Wound Healing |
| Shift Bioscience | Cambridge, UK | Small molecule for skin care/anti-aging |
| Clinical-Microbiomics | , | Merged with MS-Omics, DNASense, CosmosID to become Cmbio, Oct 2023 |
| dMed Biopharmaceutical | , | Renamed Caidya, Oct 2022 |
| |
Lyon, France | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Verana Health | San Francisco, CA | Clinical Database |
| , | Shut down Jul 2025 | |
| LDR Global | , | Acquire by Zimmer Biomet, Jun 2016, $1B |
| Doloromics | , | Shut down Mar 2025 |
| Mirati Therapeutics | , | Acquired by BMS, Jan 2024, $4.8B |
| SeraNovo | Leiden, Netherlands | Oral Formulation/ Oral Drug Delivery Technologies |
| Revvity | Kennesaw, GA | Diagnostics, Services |
| Focus Synthesis | , | Website gone, business registration not to date Jan 2019 |
| Advanced BioScience Labs | Rockville, MD | Contract Research & Manufacturing |
| MacroPore | , | Gone |
| Tyligand Bioscience | Shanghai, China | Small Molecules Targeting Cancer and Autoimmune Diseases |
| IMBdx | Seoul, Korea | Cell-free DNA Diagnostics |
| Unither Pharmaceuticals | Coutances, France | CDMO |
| La-Pha-Pack | Uithoorn, Netherlands | Packaging |
| CloudLIMS | Wilmington, DE | Laboratory Information Management System software |
| Vanqua Bio | Chicago, IL | Small Molecules Targeting Neuro Indications |
| Cosmederm Bioscience | , | Bankrupt, Oct 2017 |
| AdrenaCard | , | Gone 2019 |
| Arthus Biosystems | , | Shut down Oct 2015 |
| Tirupati | New Delhi, India | Generics |
| Jiuzhou Pharma | Nanjing, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Cinclus Pharma | Stockholm, Sweden | GERD Treatment |
| Lonza | Rockland, ME | Contract Manufacturing, Primarily Biologics but also others |
| Medosome Biotec | Alachua, FL | Small Molecules, Biologics, |
| Noema Pharma | Basel, Switzerland | Small Molecules |
| ReSearch Pharmaceutical Services | , | Acquired by PRA, renamed RPS Strategic Solutions Division |
| Tagworks Pharmaceuticals | Nijmegen, Netherlands | Antibody-Drug Conjugates |
| AMR Bio | Brighton, UK | Antimicrobials |
| Windgap Medical | Watertown, MA | Long-term stable epinephrine Injection |
| Catalyst Biosciences | , | Renamed Gyre Therapeutics |
| MitoKor | , | Bought by Micrologix Biotech Apr 2004 |
| Zylera Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Forkhead BioTherapeutics | , | Linkedin gone, website down Jul 2024 |
| Ganymede | Palo Alto, CA | Lab Automation |
| Sialix | , | Rebranded as Siamab Therapeutics, Jul 2014 |
| Structure Based Design | , | Website dated 2007 as of Mar 2018 |
| Valneva | Livingston, UK | Biologics Manufacturing |
| PharmacoFore | , | Now Signature Therapeutics |
| Image Analysis Group | London, UK | Medical Imaging CRO |
| MedAbome | Yavne, Israel | Discovery and development of innovative therapeutic mAbs, immuno-oncology |
| Lumenis | Fukuoka, Japan | Energy-based medical treatments |
| Sekisui Diagnostics | Exton, PA | Diagnostics |
| Denovo Biopharma | Hangzhou, China | Biomarker technology |
| cmbio | Vedbæk, Denmark | Omics, Bioinformatics, Software Platforms |
| Afferon | , | Gone, no info |
| AntibioTx | , | Renamed UNION Therapeutics, Oct 2018 |
| Indicia Biotechnology | , | Acquired by Platine Pharma Services, Jun 2013 |
| Biogen Idec | , | Reverted to Biogen, Mar 2015 |
| Oxford Drug Design | Oxford, UK | Antibiotics |
| Agathos Biologics | Fargo, ND | Biomanufacturing Analytical Services & Technology |
| Panacea Biotec | New Delhi, India | Differentiated generics, vaccines, biosimilars |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| SaNOtize | Vancouver, BC | Nitric Oxide for Topical Infections |
| Epics Therapeutics | Gosselies, Belgium | RNA Therapies |
| jCyte | Newport Beach, CA | Progenitor cell-based technology in retinal diseases |
| Metis Laboratories | , | |
| DA VOLTERRA | , | Website down Dec 2022 - Apr 2023 |
| Sandoz | Kundl, Austria | Generics, Biosimilars |
| Alibion | , | Website down May 2021 - Sep 2021 |
| Omniseq | , | Acquired by LabCorp, 2021 |
| Aptamer Group | York, UK | Aptamer selection and development services |
| Prompt Diagnostics | Baltimore, MD | Molecular Diagnostics |
| SyStemix | , | Acquired by Novartis, Jan 1997 |
| CloudLIMS | Indore, India | Laboratory Information Management System software |
| Metris Therapeutics | , | Presumed Gone |
| Serametrix | , | Acquired by Caprion Biosciences, Apr 2019 |
| ACROBiosystems | Frankfurt, Germany | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| GenomOncology | Cleveland, OH | Software-based solutions for precision oncology |
| NovoMedix | San Diego, CA | Small molecules |
| Venus MedTech | Hangzhou, China | Transcatheter heart valves |
| Resonetics | San Jose, Costa Rica | Contract Medical Device Manufacturing & Development |
| Puhe Biopharma | Suzhou, China | Small Molecules Targeting Oncology |
| , | Acquired by Sebia, Sep 2024 | |
| GSK | Harlow, UK | Small Molecules, Vaccines, Biologics |
| Zeneca | , | Merged with Astra to form AstraZeneca 1998 |
| CONMED | Largo, FL | Surgical, Medical Devices |
| Searchlight Pharma | Montréal, QC | Specialty Pharmaceuticals |
| Boehringer Ingelheim | Ridgefield, CT | Small Molecules, Biologics |
| Pardes Biosciences | , | Acquired by MediPacific, Aug 2023; Product failed Apr 2023, strategic alts |
| T2 Biosystems | , | Almost all employees gone, Mar 2025; Strategic Alternatives, May 2023 |
| Cardioinsight Technologies | , | Acquired by Medtronic, Jul 2015 |
| Rules-Based Medicine | , | Acquired by Myriad Genetics, Apr 2011, $80M; rebranded Myriad-RBM |
| Grifols | Barcelona, Spain | Diagnostics, Plasma Derivatives |
| Neurelis | San Diego, CA | License, develop, and commercialize product candidates |
| BioMS Medical | , | Gone? |
| Fluxus | Sunnyvale, CA | Photonics, engineering, chip fabrication, assay development, and reagent manufacturing |
| Tiamat Sciences | , | Website taken over Dec 2024 - Feb 2025 |
| Santhera Pharmaceuticals | Pratteln, Switzerland | Orphan Neuromuscular Disease Targets |
| Sistemic | , | Website down May 2021 - Feb 2022 |
| Celregen | Hangzhou, China | iPSC |
| DLRC Group | Cambridge, MA | International consulting group, supporting the Pharma & Biotech community |
| Electrome | Los Angeles, CA | AI for Bioelectric Therapy |
| Sonopor | , | Website down Mar 2022 - Sep 2022 |
| Senzime | Uppsala, Sweden | Devices |
| Cytonome | , | Shut down Nov 2009; fka Teragenics |
| Millendo Therapeutics | , | Merged with Tempest Therapeutics, Jun 2021 |
| coremap | Burlington, VT | High-resolution cardiac electrophysiology mapping system |
| Kyntra Bio | San Francisco, CA | Biologics, Small Molecules |
| SK Biotek | , | part of SK pharmteco |
| Tau Therapeutics | , | Merged with Xdynia to become Cavion, Aug 2014 |
| Fresenius Kabi | Guadalajara, Mexico | Contract Manufacturing |
| Sphere Fluidics | , | Renamed Sphere Bio, Feb 2025 |
| Convexity Scientific | , | Acquired Wellinks, Jan 2020, took name |
| Nalu Medical | Carlsbad, CA | Medical Devices |
| Adragos Pharma | Halden, Norway | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Mabion | Konstantynów , Poland | Monoclonal Antibodies |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Sentynl Therapeutics | Solana Beach, CA | Small Molecules |
| Lonza | Lexington, MA | Contract Manufacturing, Development; Lab Systems, Research Products |
| Velabs Therapeutics | , | Renamed Veraxa Biotech, Jun 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Lenire Biosciences | , | Shut down Nov 2023 |
| Arc Bio (1) | , | Merged with Dovetail Genomics to become Cantata Bio, Jun 2022 |
| C-Tri | , | Renamed Mediforum Pharmaceuticals |
| ORIC Pharmaceuticals | South SF, CA | Cancer, drug resistance |
| Validation Associates | Herndon, VA | Validation Consulting |
| TransMolecular | , | Assets Sold to Eisai 2011 |
| NeoRx | , | Changed name to Poniard, May 2006 |
| Stratus Therapeutics | Cambridge, MA | Off-the-shelf hematopoietic stem cell therapies |
| SEKRIS Biomedical | , | Not an active CA business, Sep 2019 |
| Sea Lane Biotechnologies | , | Assets acquired by i2 Pharmaceuticals, May 2017 |
| Neoneuron | Rockville, MD | Neural Stem Cell Products for Brain Repair |
| NeuroPharm | , | Liquidated 2010 |
| IQVIA | San Diego, CA | Clinical Research |
| Nitrase Biosciences | , | Renamed Nitrase Therapeutics, 2021 |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Porocel | , | Acquired by Evonik, Aug 2020, $210M |
| EyeRx Research | , | in RD as of 2019, founded 2003, no real LI employees, website probably not updated since founded |
| Oxagen | , | Website gone Feb 2022; Product rights were sold |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Synergia Medical | Mont St Guibert, Belgium | Neuromodulation |
| Yaupon Therapeutics | , | Changed Name to Ceptaris Therapeutics Jan 2012 |
| Clovis Oncology | , | Liquidated, Jul 2023; Bankruptcy filing Dec 2022 |
| Nimbus Apollo | , | Subsidiary of Nimbus Therapeutics sold to Gilead, Apr 2016, $400M |
| Regado Biosciences | , | Reverse Merged with Tobira, Jan 2015, presumably so Tobira could go public |
| MIVI Neuroscience | Eden Prairie, MN | Neuro Catheters |
| Avacta Group | London, UK | Drug Development Platform, Engineered Antibodies |
| , | Website down Jan 2026 - May 2026 | |
| FairJourney Biologics | Porto, Portugal | Antibody Discovery Services |
| Prionics | , | Acquired by Thermo Fisher, Mar 2014 |
| KWS BioTest | , | Acquired by Charles River, Jan 2018, £15M |
| , | Absorbed into parent, bridgebio, Feb 2026 | |
| DisperSol Technologies | , | Renamed AustinPx, Sep 2022 |
| Rumi Scientific | Brooklyn, NY | Brain-like Organoid |
| LeMaitre Vascular | Docklands, Australia | Vascular surgical devices |
| Broken String Biosciences | Cambridge, UK | Gene Edited Cell & Gene Therapy |
| Souffle Therapeutics | Watertown, MA | siRNA and other cell-specific therapies |
| TQ Therapeutics | Planegg, Germany | Cell & Gene Therapy Manufacturing Platform |
| , | Website down Dec 2025 - Jun 2026 | |
| Anticancer Bioscience | Chengdu, China | Precision Oncology |
| , | Acquired by Novanta, Jun 2026 | |
| Smith and Nephew | Hull, UK | Sports Medicine, Trauma, Wound Care, etc. |
| ProtaGene | Heidelberg, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Orchid Orthopedic Solutions | Bridgeport, MI | Contract Medical Device Work |
| HiberGene Diagnostics | , | Website down Dec 2022 - Apr 2023 |
| Omega Pharma | , | Acquired by Perrigo, Mar 2015 |
| Intuitive Surgical | Sunnyvale, CA | Medical Devices |
| Entrepix | , | Acquired by Amtech Systems, 2023 |
| Valerion Therapeutics | , | Dissolved, Jun 2021; fka 4s3 Bioscience |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| CorWave | Clichy, France | Blood Pumps |
| Via Pharmaceuticals | , | Shell Company |
| IBL America | Minneapolis, MN | Antibodies, lab reagents |
| Telis Bioscience | , | Renamed Alvea |
| Aitia | Cambridge, MA | Analytics |
| MDimune | Seoul, Korea | Drug Delivery Based on Cell-Derived Vesicles |
| Baxalta | , | Bought by Shire, $32B, Jun 2016 |
| TD2 Precision Oncology | Scottsdale, AZ | Oncology Clinical Research |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| CMP Therapeutics | , | Dissolved, May 2015 |
| Apica Cardiovascular | , | Acquired by Thoratec, Jul 2014 |
| Radiomics | North York, ON | AI Image Analysis & Diagnosis |
| Leon Research | León, Spain | CRO & Pharma Consulting |
| |
Comu, Romania | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| BioPointe Scientific | , | Subsumed into parent |
| Q-Linea | Uppsala, Sweden | Blood Analysis Device |
| Cambridge Biotechnology | , | Acquired by Biovitrum, Mar 2005 |
| Microline Surgical | Beverly, MA | Minimally invasive therapeutic solutions |
| BBI Solutions | Cape Town, South Africa | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Image Analysis Group | Philadelphia, PA | Medical Imaging CRO |
| Aetheria Therapeutics | , | Website Gone, Feb 2016 |
| Curate Biosciences | , | Website down Aug 2024 - Feb 2025; fka GPB Scientific |
| , | Website down Jul 2025 - Jan 2026 | |
| Comar | Voorhees, NJ | Contract Medical Device Manufacturing |
| Lumena Pharmaceuticals | , | Bought by Shire, May 2014, $260M + $90M for milestone possibilities |
| Mardil Medical | , | Website gone Feb 2021 |
| Advanced Clinical | Deerfield, IL | Clinical Research Organization |
| Allyx Therapeutics | New Haven, CT | Oral Treatment for Alzheimer's |
| Carbon Biosciences | Waltham, MA | Gene Therapy |
| Veristat | Frejus, France | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Stelvio Oncology | , | Gone late 2019 |
| Transtimulation Research | , | President gone, website outdated showing him still there. Doubt this company is active. |
| Culture Biosciences | South SF, CA | Contract Fermentation |
| Solara Active Pharma Sciences | Mumbai, India | Contract Research, Manufacturing, Regulatory Services |
| Cellmedix | , | Website down Apr 2021 - Dec 2021 |
| Aidoc | Tel Aviv, Israel | Radiology, Cardio, Neuro AI |
| Heritage Pharmaceuticals | , | Part of Emcure |
| Virtual Incision | Lincoln, NE | Surgical Robot |
| Noria Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Noden Pharma | , | Acquired by LXO Group, 2022 |
| Nocion Therapeutics | Watertown, MA | Nocions which preferentially target activated sensory neurons that are responding to external insult |
| Cerimon Pharmaceuticals | , | Gone |
| Replete Biotics | , | Website down Dec 2022 - Apr 2023 |
| IGIA Pharmaceuticals | , | Website down Jul 2023 - Dec 2023, LI gone Dec 2023 |
| Vitrisa Therapeutics | , | Website gone May 2020 - Aug 2021; not in NC business registry |
| Alzamend Neuro | Atlanta, GA | Alzheimer's Treatment |
| Proteintech | Wuhan, China | Research Antibodies |
| Advanced Genomic Technology | , | Website down Mar 2024 - Jul 2024 |
| OmniGene Bioproducts | , | Acquired by BioEnergy |
| In3Bio | , | Website under construction Jul 2023 - Dec 2023; fka Bioven |
| Reetoo Biotechnology | Shenzhen, China | AI Diagnostic Platform |
| Promedica International | , | Acquired by Iuvo BioScience, Jan 2024 |
| OraSure | Bethlehem, PA | Diagnostics |
| Unicyte | , | Website down Dec 2024 - Mar 2025 |
| , | Website down Oct 2025 - Feb 2026 | |
| Serna Bio | Stevenage, UK | Small Molecule Drug Discovery |
| , | Acquired by IMA Group, Oct 2025 | |
| ModeX Therapeutics | Weston, MA | Biologics |
| Neuraxpharm | Langenfeld, Germany | Generics |
| MultiVir | , | Website down Jun 2021 - Oct 2021; Basically a reincarnation of Introgen Pharmaceuticals |
| TYK Medicines | Shanghai, China | Tumor Therapies |
| Bio Ligament | , | Renamed Scaffold Biologics, Mar 2018 |
| PhotoThera | , | Ceased operations Dec 2012 |
| Monarch Biosciences | , | No news Jan 201 - Feb 2025; Not registered in MA, Sep 2022 - Feb 2025 |
| Gloucester Pharma | , | Bought by Celgene 2009 |
| Theolytics | Oxford, UK | Oncolytic Adenovirus Therapies |
| Spectrum Pharmaceuticals | , | Acquired by Assertio, Apr 2023, $248M |
| ImmuneBridge | San Francisco, CA | Allogeneic immunotherapies for cancer |
| Sexton Biotechnologies | , | Acquired by BioLife Solutions, Sep 2021 |
| Concordia Healthcare | , | Now Concordia International |
| Morphocell Technologies | Laval, QC | iPSC derived liver tissues |
| Ambit Biosciences | , | Bought by Daiichi Sankyo, Nov 2014 |
| Nitrome Biosciences | , | Renamed Nitrase Biosciences |
| Anosys | , | Acquired by Chromos Molecular Systems, Dec 2001 |
| Cambridge Biomedical | , | Acquired by Bioagilytix, Nov 2019 |
| Niche Generics | Dublin, Ireland | Contract Generics |
| VerGo Pharma Research | , | Website gone, Jan 2019 |
| Affinity Life Sciences | Amherst, NH | Contract Manufacturing; biologics & small molecules |
| , | Reportedly Closed Mar 2026 | |
| Antheia | Menlo Park, CA | APIS created from yeast-based fermentation |
| Twentyeight-Seven Therapeutics | , | Renamed Redona Therapeutics, Jan 2023 |
| Cognitive Research Corporation | St. Petersburg, FL | CNS CRO |
| Vitality Robotics | Durham, NC | Custom Machine Learning Models |
| Unither Pharmaceuticals | Colomiers, France | CDMO |
| AngioGenex | , | Website down Aug 2023 - Jan 2024 |
| NeuroOne | Eden Prairie, MN | Cortical Electrodes |
| GeneQuine Biotherapeutics | , | renamed QQ Bio, May 2023 |
| Spiriplex | , | Bankrupt, Mar 2023 |
| Effipharma | , | Marked as closed by Google |
| Shield Therapeutics | Wollerau, Switzerland | Small Molecules |
| AGILeBiotics | , | Shut down 2024? |
| ExsoMed | , | Acquired by Acumed, Jul 2022 |
| Deep Brain Innovations | , | Website down May 2024 - Jul 2024, employees gone |
| iCell Gene Therapeutics | Stony Brook, NY | Gene Therapy for Cancer |
| Cambridge Epigenetix | , | Renamed Biomodal, Apr 2023 |
| MyOme | Palo Alto, CA | Genomic Analysis |
| Purinomia Biotech | , | |
| Biofocus | , | Bought by Charles River Labs, Mar 2014, $179M |
| Aragon Pharmaceuticals | , | Bought by J&J, Jun 2013, $1B |
| Oncobiologics | , | Renamed Outlook Therapeutics, Dec 2018 |
| CRI Lifetree | , | Part of PRA Health Sciences |
| Abiomed | , | Acquired by J&J, Dec 2022, $16.6B |
| Motus Therapeutics | , | Bought by Allergan, Oct 2016, $200M |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Mercury Therapeutics | , | Now Mercury Pharmaceuticals |
| FIT Biotech | , | Bankrupt Feb 2019 |
| EIP Pharma | , | Merged with Diffusion Pharmaceuticals, Apr 2023 to become Cervomed |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Scioderm | , | Bought by Amicus Aug 2015, $229M+$618M milestones |
| BioSante Pharmaceuticals | , | Merged into ANI Pharmaceuticals Jun 2013 |
| Synovel Sciences | , | Bought by Fountain Pharma, Jan 2017 |
| NovaLead Pharma | Pune, India | Small Molecules |
| Avanos Medical | Surrey, UK | Pain Management, Respiratory, IV Devices |
| Cellevolve Bio | , | Shut down Aug 2023 |
| PCT Cell Therapy | , | Acquired by Hitachi, Mar 2017, $75M, rebranded as Hitachi Chemical Advanced Therapeutics Solutions |
| Honeycomb Biotechnologies | Waltham, MA | HIVE scRNAseq Solution |
| Meda Pointe Pharmaceuticals | , | Now Meda Pharmaceuticals |
| Mobiosense | , | Website down Apr 2024 - Aug 2024 |
| Macroceutics | , | Acquired by HotSpot Therapeutics, Aug 2019 |
| Arterys | , | Acquired by Tempus, Feb 2023, became Tempus Radiology |
| , | Website down Nov 2025 - Apr 2026 | |
| Barrier Therapeutics | , | Bought by Stiefel |
| PeptiFinder Biotech | Natick, MA | mRNA Display |
| , | Website down Jan 2026 - May 2026 | |
| , | Renamed Trace Biosciences | |
| Algos Pharmaceutical | , | Merged into Endo, Jul 2000 |
| Welichem Biotech | , | Seem gone, Jun 2021 |
| Coldstream Laboratories | , | Bought by Piramal |
| Customized Therapeutics | , | Business Lapsed 2011 |
| Canwell Pharma | Woburn, MA | Dual-drug ADCs |
| Shasun Pharmaceuticals | , | Merged with Strides Arcolab, Nov 2015 |
| Centaur Pharmaceuticals | Mumbai, India | Small Molecules, APIs, Generics |
| Ena Therapeutics | , | Renamed Ena Respiratory |
| Bon Opus Biosciences | Millburn, NJ | Synthesis - Proteins, Antibodies, Peptides, Genes |
| Attune Pharmaceuticals | , | Website down Aug 2024, no news since Jul 2019 |
| Sun Pharmaceuticals | Tiszavasvari, Hungary | Generic Small Molecules, APIs |
| Emergent BioSolutions | Berwyn, PA | Biologics, Contract Manufacturing, Biodefense |
| Ocular Proteomics | , | Website down Apr 2021 - Sep 2021 |
| Hypromatrix | , | Gone 2007 |
| Salvat | Madrid, Spain | Small Molecules |
| , | Now PiSA USA | |
| Proteins and Peptide Management | , | Now Adocia |
| Epicept | , | Merged with Immune Pharmaceuticals, Aug 2013 |
| Ovation Pharmaceuticals | , | Acquired by Lundbeck 2009 |
| Remora Therapeutics | , | Shut down 2021 |
| |
Hyderabad, India | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS India is a stand-alone full service Clinical Trials Unit, with a Bioanalysis lab for clinical trial sample analysis. |
| Acumen Bioscience | , | Renamed TTP Labtech, Sep 2003 |
| Cambrian Bioworks | Bengaluru, India | Lab Instruments, Kits |
| QiXia Decode Therapeutics | , | no info, May 2022 - Dec 2024, China-based |
| X-BODY | , | Bought by Juno Therapeutics, Jun 2015, $21M + stock + milestones |
| Univfy | Los Altos, CA | IVF reports |
| Kanglaite | , | Website down Jan 2019 - Jun 2019 |
| Telesis Bio | San Diego, CA | Synthetic DNA |
| , | Website down Aug 2025 - Jan 2026 | |
| Bright Path Laboratories | Kannapolis, NC | Continuous Generic Manufacturing |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Day One Biopharmaceuticals | Brisbane, CA | Cancer Treatments |
| Anfiro | , | Shut down Dec 2019 |
| D-Pharm | , | Website Gone, Aug 2016 |
| Basilea Pharmaceutica | Allschwil, Switzerland | Topical |
| Protein Genomics | , | Website copyright 2008 in Mar 2019 |
| BioVascular | , | 2007 website as of Mar 2019 |
| RxFunction | Eden Prairie, MN | Balance and Mobility Device for Peripheral Neuropathy |
| Precision Optics | Gardner, MA | Endoscopes and Optical Devices |
| Regenative Labs | Pensacola, FL | Allograft for Breast Reduction Recovery |
| Cyprotex | , | Acquired by Evotec, Dec 2016, £ 55.7M |
| Exponential Business & Technologies | Eden Prairie, MN | Analytical Lab Services |
| TriRx Pharmaceutical Services | Segré-en-Anjou-Bleu, France | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| FHC | Bowdoin, ME | Medical Devices |
| KBI Biopharma | Boulder, CO | Contract Development & Manufacturing |
| Derma Sciences | , | Acquired by Integra, Feb 2017, $240M |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Hibernaid | , | Website down Sep 2021 - Jan 2022 |
| Eris Lifesciences | , | Website down Oct 2022 - Mar 2023 |
| Excelra | Iselin, NJ | Data Science & Informatics Services |
| Vince & Associates | , | Seems to have been subsumed into Altasciences |
| Eidos Therapeutics | , | Merged with BridgeBio, Jan 2021 |
| Boston Institute of Biotechnology | Southborough, MA | Contract Research & Development |
| SonarMed | , | Acquired by Medtronic, May 2021 |
| Gastrotech | , | Now Rose Pharma |
| Nabla Bio | Cambridge, MA | Antibody Design |
| Stimdia Medical | Mendota Heights, MN | Minimally invasive, temporary, neuromuscular stimulation system |
| Getinge | Vendôme, France | Medical Technology |
| Ellipses Pharma | London, UK | Acquisition, Development, Out-Licensing |
| Bone Medical | , | Company ceased doing RD in 2015, now pursuing 'investments' according to annual report |
| Lung Therapeutics | , | Acquired by Aileron Therapeutics, Oct 2023 |
| Innovative Therapies | , | Acquired by Cardinal Health, Aug 2014 |
| Affinity BioReagents | , | Acquired by Thermo Fisher, Jul 2008 |
| URL Pharma | , | Bought by Takeda Apr 2012, Bought by Sun Pharma Dec 2012 |
| Isentio | , | Merged with PathoGenomix, Sep 2015 |
| Ascent Development Services | , | Acquired by PharmaLex, Feb 2022 |
| Cequent Pharmaceuticals | , | Merged with mdRNA, became Marina Biotech 2010 |
| Aushon Biosystems | , | Acquired by Quanterix, Jan 2018 |
| ITC | , | Acquired Accumetrics, Rebranded as Accriva Diagnostics |
| Coordination Therapeutics | , | Not Active |
| InSilixa | , | Website down Apr 2022 - Aug 2022 |
| Yunovia | Hwaseong, Korea | Small Molecules |
| Argene | , | Acquired by bioMérieux, Jul 2011, $60M |
| OxUs | Auburn Hills, MI | Portable oxygen concentrator |
| Cytune Pharma | , | Bought by SOTIO, Aug 2018 |
| Clinical Link | Winston-Salem, NC | Clinical Trial Data Capture |
| PCI Pharma Services | Burlington, ON | Contract Manufacturing, Services |
| Humane Genomics | New York, NY | Precision-designed oncolytic viral therapies |
| Abound Bio | , | Acquired by Galapagos Jun 2022, $14M |
| Sanos | Soborg, Denmark | Clinical Research Organizations |
| Life Technologies | , | Bought by Thermo-Fisher, Apr 2013, $13.6B |
| Nuvik Therapeutics | , | No website, very little info |
| British Biotech | , | Merged into Vernalis 2003 |
| , | Website down Dec 2025 - Apr 2026 | |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| SoftGenetics | State College, PA | Software for genetic analysis |
| MicroPort | Santo Domingo, Dominican Republic | Medical Devices |
| EverGaze | , | Website down Dec 2021 - Jul 2022 |
| Iquity Labs | , | Merged into Decode Health |
| ChemGen | , | Bought by Elanco (Lilly) Jan 2012 |
| Pattern Genomics | , | Acquired by Intus Bio, Jun 2023 |
| Tioga Research | San Diego, CA | Contract R&D for Topicals |
| MedAutonomic | , | Business filings late, Sep 2022 - Feb 2025 |
| AbbVie | Belgrade, Serbia | Small Molecules, Biologics |
| Alphora Research | , | Acquired by eurofins, Jun 2017 |
| AesRx | , | Bought by Baxter, Jul 2014 |
| Flamma | Isso, Italy | Contract Manufacturing & Services |
| Aceto | , | Renamed Actylis, Sep 2022 |
| CrelioHealth | Columbia, MD | LIMS |
| Unicorn Biotechnologies | Sheffield, UK | Cell Culture Production Platform |
| XL-protein | Freising, Germany | Drug delivery technology (alternative to pegylation) |
| Clarify Medical | , | Renamed Zerigo Health, Oct 2020 |
| Geospiza | , | Acquired by Perkin Elmer, May 2011, $?? |
| Aggamin Pharmaceuticals | , | Founded 2010, business registered in NY 2018, but no employees on LI, dated information-less website |
| Haffkine Biopharmaceuticals | Mumbai, India | Small Molecules, Vaccines, Antitoxins |
| , | Acquired by Tecan, Aug 2021 | |
| FabGennix | Frisco, TX | Antibodies, Kits, reagents |
| Inreda Diabetic | Goor, Netherlands | Artificial pancreas |
| Ritter Pharmaceuticals | , | Merged into Qualigen, May 2020, took its name |
| Sheffield Pharmaceuticals | , | Merged with Pipex Pharmaceuticals who took the Sheffield name and were later renamed Adeona Therapeutics |
| Orbytel Group | Bethlehem, PA | Software Solutions |
| CellabMED | Seoul, Korea | Therapeutic Antibodies, CMO |
| Trilogy Writing & Consulting | Frankfurt am Main, Germany | Medical Writing |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| , | Acquired by Supernus Pharmaceuticals, Jul 2025, $561M + Milestones | |
| CSL Seqirus | Maidenhead, UK | Flu vaccine |
| Click Diagnostics | , | Renamed Visby Medical, Jun 2019 |
| Inhale Therapeutics | , | Renamed Nektar Therapeutics |
| Delphi Genetics | , | Acquired by Catalent, Feb 2021 |
| Suppremol | , | Acquired by Baxter, Mar 2015, €225M, part of Baxalta now |
| Biosynth | Bratislava, Slovakia | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Opis Research | Desio, Italy | Clinical Research |
| Cadex Genomics | , | Shut down Jul 2024 |
| Ignyta | , | Acquired by Roche, Feb 2018; $1.2B |
| Mabimmune | , | Merged with Neurimmune |
| Meadowhawk Biolabs | Hayward, CA | Small & Large Molecule CRO |
| Smart Biosciences | , | Renamed sb-Peptide |
| Vesper Medical | Wayne, PA | Venous Stent |
| AdvanBio | Irvine, CA | Bioanalysis, Assay Development, Regulatory Consulting |
| Avania | Marlborough, MA | Medical Device Clinical Research |
| Seed Therapeutics | New York, NY | Molecular glues - therapeutics that degrade disease-causing, undruggable proteins |
| Qserve Group | Arnhem, Netherlands | Quality, Regulatory, Clinical Consulting |
| Glenmark | Monroe, NC | Generic Small Molecules |
| Viroxis | , | Acquired by an oil company, folded into Santalis, Jun 2015 |
| ViewsML Technologies | Vancouver, BC | Immunohistochemistry |
| NewHeart Devices | , | Gone |
| Stada | Vršac, Serbia | Generics |
| Imaxio | , | Website down Aug 2024 - Feb 2025 |
| Leuvas Therapeutics | , | Website down May 2020; Not registered in CA Dec 2019 |
| SEQENS | Couterne, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| Patch Biosciences | , | Acquired by Gingko Bioworks, Feb 2024 |
| Mast Group | Reinfeld, Germany | Cell Systems, Reagents, Assays |
| Bharat Biotech | Hyderabad, India | Injectables, Vaccines, Contract Work |
| |
New York, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Edgemont Pharmaceuticals | , | 11 year old side-gig with no website as of Nov 2019 |
| Champions Biotechnology | , | Now Champions Oncology |
| Baliopharm | , | Acquired by Promethera Biosciences, Apr 2018 |
| Asimov | Boston, MA | Cell line development, biologic and viral vector production, synthetic biology |
| Corza Medical | Boulder, CO | Surgical Devices |
| Fresenius Kabi | Anápolis, Brazil | Contract Manufacturing |
| Histogen | , | Chapter 11 Bankruptcy plus wind down Apr 2024; Acquired Conatus Pharmaceuticals, Jun 2020 to go public |
| , | Renamed Suntra MedTech Solutions, Sep 2025 | |
| Cenexi | Braine-l’Alleud, Belgium | Sterile Pharmaceutical Manufacturing |
| MiaMed | , | Bought by Amicus Therapeutics, Jul 2016, $6.5M cash/stock + $85M milestones |
| SightScience | , | Website down Aug 2022 - Feb 2023; University of Aberdeen spinout |
| Perspix Bioscience | , | Merged with BioCopy, Apr 2024 |
| Charles River Laboratories | Kingston, NY | Research Animal Models and Preclinical Research |
| IMUNA PHARM | Michaľany, Slovakia | Contract Manufacturing |
| Biodextris | Laval, QC | Analytical and process development for vaccines/biologics, manufacturing services of prokaryote and eukaryote-derived proteins |
| MyCartis | , | Website down Aug 2022 - Jan 2023 |
| Asgard Therapeutics | Lund, Sweden | Cancer Immunotherapy |
| HOOKIPA Pharma | , | Winding down Jul 2025 |
| Betagenon | , | Renamed Amplified Therapeutics, Mar 2023 |
| Longevity Biomedical | Bothell, WA | Noninvasive stroke and vascular disorder treatment device |
| SoBran | Falls Church, VA | Preclinical Services |
| Essen Instruments | , | Renamed Essen Bioscience, Apr 2010 |
| Elypta | Solna, Sweden | Liquid Biopsy |
| JMI Labs | North Liberty, IA | Antimicrobial Therapy Work |
| Oasis Pharmaceuticals | , | SBIR recipient, no info |
| Srini Pharmaceuticals | Hyderabad, India | APIs |
| GenNext Technologies | Half Moon Bay, CA | Protein Structural Analysis |
| Voxeleron | Austin, TX | Ophthalmic Image Analysis |
| Empyrean Neuroscience | New York, NY | Small Molecules Derived from Plants and Fungi |
| Laboratoires Dausse | , | Merged with Laboratoires Robert & Carrière in 1970 to become Synthélabo |
| NeuroClues | Louvain-la-Neuve, Belgium | Eye Tracking Diagnostic |
| 20/20 Gene Systems | , | Renamed 20/20 BioLabs, Apr 2025 |
| Novolytics | , | Website gone, key assets acquired by AmpliPhi Jan 2016 |
| |
Münster, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| AnaBios | San Diego, CA | Human Tissue Clinical Testing |
| Meros Polymers | , | Website down Dec 2018 - Mar 2019 |
| Spring Bank Pharmaceuticals | , | Merged with F-star, Jul 2020 |
| Marker Therapeutics | Houston, TX | Cell Therapy |
| InnarisBio | , | Website down Mar 2024 - Jul 2024 |
| EndoLogic | , | Seems inactive, Aug 2023 |
| Genmab | Utrecht, Netherlands | Biologics |
| Tigercat Pharma | , | Changed name to Menlo Therapeutics, May 2016 |
| Adesis | New Castle, DE | Custom Organic Synthesis |
| Coramed Technologies | , | Website down Feb 2021 - Aug 2021 |
| Rediscovery Life Sciences | , | Website gone Aug 2024, not registered in MA |
| Retro Biosciences | San Francisco, CA | Cell reprogramming |
| Mirrx Therapeutics | , | All tech acquired by Ranger Biotechnologies, Jul 2018 |
| Baxter | Jayuya, PR | Medication Delivery |
| Aeterna Zentaris | , | Merged with Ceapro to become Cosciens Pharma, Jun 2024 |
| Intrinsic Therapeutics | Woburn, MA | Lumbar Discectomy Implant |
| TAE Life Sciences | Foothill Ranch, CA | Boron Neutron Capture Therapy |
| , | Acquired by Bausch + Lomb, Oct 1997, $380M | |
| Spatial Transcriptomics | , | Acquired by 10x Genomics, Dec 2018 |
| ALBiotek | , | Acquired by Vaxcell Bio, Jan 2025 |
| Koios Medical | Chicago, IL | Ultrasound breast cancer detection and diagnosis |
| Arsanis Biosciences | , | Acquired by X4 Pharmaceuticals via reverse merger, Mar 2019 |
| Cell Biosciences | , | Now ProteinSimple |
| Catamaran Bio | , | Winding down Jan 2024 |
| Leucadia Pharmaceuticals | , | Website down Aug 2022 |
| Ameridose | , | Shut Down 2012 |
| Saluda Medical | Macquarie Park, Australia | Spinal Cord Stimulation Device |
| Agilent | Diegem, Belgium | High-Throughput Screening Equipment, Imaging instruments |
| Elitra Pharmaceuticals | , | Merged with Syrxx as Trilogy Pharmaceuticals |
| MabSwitch | Van Nuys, CA | Regulatable Antibodies |
| Reinnervate | , | Acquired by ReproCELL, combined with Biopta to become ReproCELL Europe, Jul 2016 |
| InvivoGen | San Diego, CA | Life Science Reagents |
| MandalMed | , | Possibly rebranding as Bioscience Laboratories, Jan 2019 |
| Clinical Metabolomics | , | Aka Clinmet, Website gone Sep 2017 |
| Kimia Therapeutics | Berkeley, CA | Treatment for metabolic disease |
| Bone Solutions | Colleyville, TX | Magnesium-based Bone Substitute |
| Zentiva | Prague, Czech Republic | Generic Small Molecules |
| Viravaxx | , | |
| AstraZeneca | Macclesfield, UK | Small Molecules, Vaccines, Biologics |
| Biolab | Mississauga, ON | Small Molecules |
| Arisan Therapeutics | Carlsbad, CA | Infectious diseases |
| FSD Pharma | , | Renamed Quantum BioPharma, Aug 2024 |
| Exosome Sciences | , | Website down Dec 2022; Majority-owned by Aethlon Medical |
| Ariosa Diagnostics | , | Bought by Roche, Dec 2014, $400M+$225M contingent |
| Intercell | , | Merged with Vivalis to become Valneva May 2013 |
| Medium Biosciences | San Francisco, CA | AI-designed Protein Therapeutics |
| AndroBioSys | , | Presumed gone |
| Saniona | Glostrup, Denmark | Small Molecules |
| Erba MDX | , | Website gone Aug 2019 |
| Avanir Pharmaceuticals | , | Website down Jan 2023 - Mar 2023; Bought by Otsuka, Jan 2015, $3.5B |
| Olympus | Center Valley, PA | Surgical Products, Imaging |
| DCN Dx | Carlsbad, CA | CDMO, dry chemistry, PCR, ELISA, microfluidics, lab-on-a-chip, microbiology, engineering |
| Neoleukin Therapeutics | , | Merged with Neurogene, Dec 2023; Went public via Reverse Merger with Aquinox Pharmaceuticals |
| Corat Therapeutics | Braunschweig, Germany | Recombinant Human Antibodies |
| Precede Biosciences | Boston, MA | Liquid Biopsy Platform |
| Suven Life Sciences | Hyderabad, India | Contract Research And Manufacturing Services |
| Vasculox | , | Renamed Tioma Therapeutics, Aug 2016 |
| Invuity | , | Acquired by Stryker, Oct 2018, $190M |
| Agilix | , | Acquired by Perkin-Elmer, Feb 2006 |
| Access Pharmaceuticals | , | Now Abeona Therapeutics |
| Bionaut Labs | Los Angeles, CA | Robot Delivery of Therapeutics |
| Vaxeal | , | Website down Oct 2023 - Apr 2024 |
| Divamics | Suzhou, China | Peptides, Small Molecule, Antibodies |
| ACT Biotech | , | Technically exists Dec 2019; Oncology assets acquired by Eddingpharm Jan 2014. |
| CuromeBiosciences | Cheongju, Korea | First-in-class medicine for intractable and rare diseases, including mitochondrial disease |
| Endocision | Montreal, QC | Minimally invasive cryogenic solutions and detachable endoscopic cryobiopsy systems |
| Protherics | , | Bought by BTG plc, Sep 2008, £218M |
| Amdipharm | , | Acquired by Concordia Healthcare, Sep 2015 |
| TumorEnd | , | Website gone Feb 2019 |
| Transcripta Bio | Palo Alto, CA | Drug Discovery for Monogenic Diseases |
| Evogene | Rehovot, Israel | Computational Biology |
| , | Website down Oct 2025 - Feb 2026, employees gone | |
| Xel Pharmaceuticals | , | Website not updated since 2008 |
| Nordson Medical | Westlake, OH | Medical Device Manufacturing |
| CryoXtract Instruments | , | Shut down pre-Aug 2017 |
| Biomatik | Wilmington, DE | ELISA Kits, Bioreagents, Custom Gene, Peptide, Protein, Antibody Services |
| Holoclara | Los Angeles, CA | Orally-available Therapies Derived From Worms |
| Ophtec | Groningen, Netherlands | Intraocular Lenses, Ophthalmology Products |
| Jungla | , | Acquired by Invitae, Jul 2019, $65M |
| Pramana | Cambridge, MA | Whole slide imaging systems |
| , | Acquired by Novartis, Mar 2026, $2B; Synnovation psuedo-subsidiary | |
| BlossomHill Therapeutics | San Diego, CA | Small Molecule Drug Discovery |
| Memory Pharmaceuticals | , | Acquired by Roche, Nov 2008 |
| Consortia Therapeutics | , | Renamed Pareto Bio |
| Sequel Pharmaceuticals | , | Gone |
| ViroSure | Vienna, Austria | Biosafety Testing CRO, Cell & Virus Banking Services |
| Biomedica | , | Now part of Oxford Biomedica |
| BGI | Hong Kong, China | Genetic Testing |
| Ab Initio Biotherapeutics | , | Acquired by Ligand Pharmaceuticals, Jul 2019, $12M |
| Magnolia Neurosciences | , | Website down Feb 2024 - Jul 2024; aka Magnolia Tejas |
| Famar | Avlonas, Greece | Contract Manufacturing - Small Molecules |
| Apurano Pharmaceuticals | Warngau, Germany | Plant Substance Drug Delivery |
| Alira Health | Framingham, MA | Consulting, Clinical Research |
| Achieve Life Sciences | Bothell, WA | Small Molecules |
| TransMedics | Andover, MA | Heart & Lung Preservation Machines |
| Cyanotech | Kailua-Kona, HI | Microalgae |
| NeuroCycle Therapeutics | , | Acquired by Engrail Therapeutics, Feb 2021 |
| Unilabs York Bioanalytical Solutions | York, UK | Bioanalytical & Biomarker Services |
| Access Scientific | , | Acquired by Smiths Medical, May 2020 |
| SanReno Therapeutics | , | Acquired by Novartis, Jan 2024 |
| Solasia Pharma K.K. | Tokyo, Japan | Licensing Western products to sell in Asia |
| ReacX Pharmaceuticals | San Francisco, CA | Innovative drug delivery platform |
| Avanyx Therapeutics | , | Renamed Boston Therapeutics, Nov 2010 |
| TX3 Services | , | Acquired by Tricentis, Mar 2022 |
| Medisyn Technologies | , | Dissolved, Dec 2016 |
| Alxerion Biotech | , | Gone May 2021 |
| BMIKorea | Jeju, Korea | Biologics, Small Molecules, Devices |
| Aratinga Bio | , | Acquired by Ixaka, Jan 2021, $54M |
| Tectonic Therapeutic | Watertown, MA | GPCR Targeting Drugs |
| Avax Technologies | , | Gone |
| Galvani Bioelectronics | Stevenage, UK | Miniaturized, implantable devices |
| PrecisionLife | Long Hanborough, UK | Analysis of patients’ genomic, clinical, and epidemiological data |
| EvolveImmune Therapeutics | Branford, CT | Novel Immunotherapy Targets |
| ActiGraph | , | Website down Apr 2023 - Sep 2023 |
| Solstice Biologics | , | Website Gone, Dec 2018, no employees with pictures on LinkedIn |
| ILEX Oncology | , | Acquired by Genzyme, Dec 2004, $1B in stock |
| Yprotech | , | Renamed Apex Molecular, Nov 2018 |
| Breathtec BioMedical | , | Renamed Algernon Pharmaceuticals |
| , | Acquired by Pathos AI, Jan 2024, $42M; fka Rain Therapeutics | |
| BioAtla | Beijing, China | Conditionally-active Biologics |
| Cytomyx | , | Acquired by Origene, fka Cambridge Bioscience |
| Prolong Pharmaceuticals | , | Execs both left late 2019 |
| GI Innovation | Seoul, Korea | Microbiome combination drug development |
| |
Cambridge, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cerberus Therapeutics | Cambridge, MA | Alpaca-derived nanobodies |
| Asklepios Biopharmaceutical | , | Renamed AskBio |
| VB Spine | Allendale, NJ | Spinal Implants |
| Biomage | , | Acquired by Parse Biosciences, Jan 2024 |
| Pfizer | McPherson, KS | Sterile Injectables |
| Arex Advisor | Stockholm, Sweden | Regulatory Affairs, CMC, Quality Assurance, Pharmacovigilance and Market Access in Nordics and EU |
| Living Cell Technologies | , | Website down Oct 2023 - Nov 2023; Penny stock |
| Tris Pharma | Monmouth Junction, NJ | Drug Delivery Technologies |
| GeneriQ Pharma | , | Website down Dec 2017-Feb 2018 |
| Patwell Pharmaceuticals | Coatesville, PA | Pharmaceutical packaging & labeling |
| , | Website down May 2025 - Dec 2025 | |
| Trinity Life Sciences | Waltham, MA | Marketing Consulting |
| Kaper Pharma | , | Website down Aug 2023 - Apr 2024 |
| Aurinia Pharmaceuticals | Edmonton, AB | Small Molecules, Diagnostics |
| Envision Pharma | , | Merged with UBC |
| Hopewell Therapeutics | Woburn, MA | Lipid Nanoparticle Delivery |
| Agena Bioscience | San Diego, CA | High throughput targeted & multiplexed genetic analysis |
| Talecris Biotherapeutics | , | Merged with Grifols |
| Northstar Neuroscience | , | Dissolved |
| |
Bon-Encontre, France | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Genome Insight | , | Renamed Inocras, Mar 2024 |
| Avant Immunotherapeutics | , | Merged with Celldex |
| Pherin Pharmaceuticals | , | Acquired by Vistagen, Feb 2023 |
| Respira Technologies | , | Renamed Qnovia, Sep 2022 |
| Jantibody | , | Acquired by H-Cyte, Sep 2022 |
| NextBio | , | Acquired by Illumina, Oct 2013 |
| Beta Bionics | Concord, MA | Artificial Pancreas |
| Aixa Bio | Cambridge, MA | AI genomics |
| Evince Biosciences | , | Website gone May 2020, Domain expired Jan 2020; Residential Address |
| MP Biomedicals | Irvine, CA | Diagnostics & Life Sciences Products |
| Recipharm | Queluz, Portugal | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Covaxx | , | Merged with United Neuroscience, Apr 2021 |
| BioMarin Pharmaceutical | Ringaskiddy, Ireland | Biologics |
| ID4Pharma | Bridgeville, PA | Multiple Myeloma Treatment |
| , | Website down Dec 2025 | |
| Precise Light Surgical | , | Website down Aug 2022 - Feb 2023 |
| New England Peptide | , | Merged with Peptides International to become Vivitide, Jan 2021 |
| ChromaTwist | Wolverhampton, UK | Fluorescent dyes for flow cytometry and microscopy |
| M13 Therapeutics | , | Renamed Gensaic, Sep 2022 |
| Straumann | Andover, MA | Dental Implants and Regeneration |
| Advancells | Noida, India | Stem Cell Treatments |
| Liof Pharma | Alava, Spain | Biologics & Injectable Fill Finish |
| Rengu Biotechnology | , | No website Mar 2020 - Aug 2021; Only Google hit is a patent |
| Oncorus | , | Liquidated, Jun 2023 |
| Cisbio | , | Acquired by PerkinElmer, Apr 2019 |
| Lifescan Canada | Burnaby, BC | Blood Glucose Meters |
| HOPO Therapeutics | Emeryville, CA | Heavy Metal Poisoning Prevention |
| Tuevol Therapeutics | , | Gone by 2020 |
| Inexia | , | Acquired by Centessa |
| FlowMetric | , | Acquired by Kcas Bio, Feb 2022 |
| SDIX | Newark, DE | Diagnostics |
| Zinsser Analytic | , | Acquired by Gardner Denver |
| Arcutis Biotherapeutics | Westlake Village, CA | Reformulated, Topical Dermatology Products |
| Integra LifeSciences | Cordova, TN | Medical Devices |
| Inventa Biosciences | , | Not Active |
| DEM BioPharma | Cambridge, MA | Cell Therapy Using Don't Eat Me Signal |
| Via Scientific | Cambridge, MA | Multi-omics Platform |
| ChunLab | , | Renamed CJ Bioscience |
| Oxular | , | Acquired by Regeneron, Jan 2025 |
| Ataraxis AI | New York, NY | AI Cancer Diagnosis |
| Altravax | , | Shut down 2016 |
| Cholestech | , | Now Alere |
| BASi Research Products | West Lafayette, IN | Scientific Instruments |
| Matisse Pharmaceuticals | Geleen, Netherlands | Heparin-derived Sepsis Treatment |
| ISurTec | St. Paul, MN | Medical Device & Labware Coatings |
| Meliora Therapeutics | San Francisco, CA | Mechanism-focused Oncology Drugs |
| Acuity Bio | , | Acquired by Cook Biotech, May 2021 |
| C/M/C Biologics | , | Now CMC Biologics |
| Primerdesign | Chandler's Ford, UK | Real-time PCR kits and reagents for molecular diagnostics |
| Ariad Pharmaceuticals | , | Acquired by Takeda, Feb 2017, $5.2B |
| Genetix Biotherapeutics | Somerville, MA | Gene Therapy, Cellular Extraction & Reintroduction |
| Cellanome | Foster City, CA | Multiomics Platform |
| , | Renamed Entirety Biomedical | |
| Nemera | Neuenburg am Rhein, Germany | Drug Delivery Systems |
| Alfigen | , | Acquired by Genzyme, Feb 2004 |
| Ionpath | , | Shut down Feb 2025 |
| , | Website down Jan 2026 - May 2026 | |
| Medgineering | , | No employees on LI, Dec 2023, not registered in MN Dec 2023 |
| Aspen Pharmacare | Munich, Germany | Small Molecules |
| Innomab | , | Gone 2017 |
| IndUS Pharmaceuticals | , | Bought by Pivot Pharmaceuticals, Nov 2015 |
| Micropulse | Columbia City, IN | Manufacturing and assembly for implants, instruments, and delivery systems |
| Palo Alto Health Sciences | , | Renamed Freespira, Dec 2020 |
| Bioagilytix | Durham, NC | Bioanalytical services, immunoassays, cell-based assays |
| Nitto BioPharma | San Diego, CA | Drug Delivery of siRNA |
| Worldwide Clinical Trials | Sofia, Bulgaria | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Dicerna Pharmaceuticals | , | Acquired by Novo Nordisk, Dec 2021, $3.3B |
| AffaMed Therapeutics | Shanghai, China | Small Molecules, Monoclonal Antibodies |
| , | No info or news 2020 - Apr 2026; Agnostic drug types | |
| Luna Innovations | Blacksburg, VA | Sensors and Systems |
| Paratek Pharmaceuticals | Boston, MA | Small Molecules |
| , | Renamed Proxoma, Jan 2026 | |
| Camel-IDS | , | Renamed Precirix, Sep 2020 |
| Parabon Nanolabs | Reston, VA | Next-generation forensic and therapeutic products |
| Oyster Point Pharmaceuticals | , | Acquired by Viatris, Jan 2023 |
| Juniper Pharmaceuticals | , | Acquired by Catalent, Aug 2018 |
| Aspen Surgical | Caledonia, MI | Surgical Equipment |
| Furong Biotech | , | |
| , | Filings late Nov 2022 - Dec 2025; New company at address; Spinout from ProActa | |
| Venta Medical | , | Gone, Apr 2017 |
| Exodos Life Science Partners | , | Main guy left for big company, website down Mar 2020 |
| Genex Pharma | Mumbai , India | Generics |
| Yokogawa | Naucalpan de Juarez, Mexico | Cell Analysis, Biological Containment, Equipment |
| Novaliq | Heidelberg, Germany | Drug Delivery |
| Veracyte | Austin, TX | Cytology Diagnostics |
| Enrich Therapeutics | , | Renamed Enrich Biosystems, Nov 2022 |
| QuintilesIMS | , | Renamed IQVIA, Nov 2017 |
| KritiKal Solutions | Noida, India | Manufacturing advanced medical devices and software |
| TargEDys | , | Acquired by Biocodex, Jun 2023 |
| Immunitas Therapeutics | Waltham, MA | Single cell genomics-based drug discovery |
| TAP Pharmaceuticals | , | Acquired by Takeda |
| GlucosAlarm | , | Website down May 2020 - Feb 2021 |
| UCB Pharma | Saitama, Japan | Small Molecules, Biologics |
| , | Website taken over Mar 2026 - Apr 2026 | |
| DICE-CRO | Groot-Bijgaarden, Belgium | Clinical Research |
| , | Winding down Jan 2026 | |
| Surepharm | , | Liquidating, Apr 2025 |
| EarliPoint Health | Decatur, GA | Autism Diagnosis |
| , | Renamed Singulera, Nov 2025 | |
| Betamab Therapeutics | , | Website down Oct 2021 - Mar 2022 |
| Versantis | , | Acquired by genfit, Sep 2022, CHF40M + CHF65M milestones |
| Contero Therapeutics | , | Website down Jun 2021 - Sep 2021, no info |
| Skyline Therapeutics | Shanghai, China | AAV Gene Therapy Capsids |
| Tissue Regenix | Universal City, TX | Replacement Body Parts |
| Luxna Biotech | Osaka, Japan | Oligonucleotide Therapeutics |
| DJS Antibodies | Oxford, UK | Therapeutic antibody discovery and design |
| Conkwest | , | Website gone Dec 2015 |
| Indocruit | , | Gone |
| AlgOss Biotechnologies | Vienna, Austria | Plant-based Bone Forming Materials |
| Passage Bio | Philadelphia, PA | Gene Therapy |
| Avomeen | , | Acquired by Element, Mar 2021 |
| BacterioScan | , | Chapter 11 Bankruptcy, Nov 2021 |
| CeNeRx | , | Shut Down, 2013 |
| CiVentiChem | , | Acquired by Sterling Pharma |
| Kelonia Therapeutics | Boston, MA | in vivo CAR T Gene Therapy |
| Theradex | West Sussex, UK | Oncology Clinical Research |
| Confluent Medical Technologies | Austin, TX | Contract Medical Devices, Nitinol, Catheters, Textiles |
| CirCode Biomed | Shanghai, China | RNA Therapeutics |
| Revelar Biotherapeutics | , | Website down Dec 2022 - Apr 2023; Twist Biosciences spinout |
| Soluble Therapeutics | , | Bought by CytoBioscience, Dec 2016 |
| PeriphaGen Holdings | , | Seems gone, Aug 2023 |
| Triax Pharmaceuticals | , | Acquired by Onset Dermatology |
| Kapplex | , | Acquired by Miroculus, Apr 2016 |
| Modifi Biosciences | , | Acquired by Merck, Oct 2024, $30M + $1.3B milestones |
| Provectus Pharmaceuticals | , | Rebranded Provectus Biopharmaceuticals, Dec 2013 |
| Madorra | Portland, OR | Vaginal Dryness Treatment |
| MicrobiomeDX | , | Website down Jul 2020 - Jan 2021 |
| PeriTec Biosciences | , | Website not updated in 6 years, person who left in 2014 still listed on team |
| , | Website down Jun 2025 - Dec 2025 | |
| Koelis | Meylan, France | Prostate Biopsy System |
| Pierre Fabre | Ussel, France | Oncology, derm / cosmetics |
| Palatin Technologies | Cranbury, NJ | Small Molecules |
| Igenomix | Toronto, ON | Contract genetic testing for reproductive health; covid-19 pcr |
| Morphiex Biotherapeutics | , | Website hijacked, delayed redirect Apr 2023, not registered in MA |
| Gordian Biotechnology | San Francisco, CA | Drug Screening Platform |
| Elto Pharma | , | Bought by Coeptis Pharmaceuticals, Nov 2018 |
| Alcon | Vernier-Geneva, Switzerland | Eye-Care Products |
| New Equilibrium Biosciences | , | Shut down Dec 2023 |
| IGC BIO | , | Website down Dec 2023 - May 2024 |
| , | Merged with Oncoinvent, Oct 2025 to become OncoInvent | |
| D-Eye | , | Website down Sep 2023 - Mar 2024 |
| MedGenome | , | Renamed Signios Biosciences, Apr 2025 |
| Inositec | , | Acquired by Vifor Pharma, Nov 2021, CHF20M |
| PlenSat | , | Website down Mar 2022 - Aug 2022; Residential address Oct 2019 |
| Smiths Medical | , | Acquired by ICU Medical, Jan 2022, $2.35B |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Sundia | , | Part of BioDuro |
| Carmel Biosciences | , | Acquired by Nutriband, Sep 2018, $2.7M |
| Erbi Biosystems | , | Acquired by MilliporeSigma, Dec 2022; fka Pharyx |
| Nvelop Therapeutics | , | |
| Neptune Medical | Burlingame, CA | Endoscope Overtube |
| Kempbio | , | Renamed Kemp Proteins, Mar 2019 |
| Zenith Epigenetics | San Francisco, CA | Orally-active small molecules |
| Akttyva Therapeutics | Watertown, MA | AI-based Drug Discovery |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Palingen | , | Renamed IGM Biosciences |
| , | Website down Dec 2025 - Apr 2026 | |
| Actimis Pharmaceuticals | , | Acquired by Boehringer Ingelheim 2008 |
| Cherry Pharmaceuticals | , | Cherry-based drugs. No website, not active, FDA warned them about medical claims on their site |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Azad Pharma | Kotayk Marz, Armenia | APIs, generics |
| Eurus Therapeutics | Fujisawa, | Non-CRISPR genome editing technologies |
| Renovia | , | Website not working Nov 2022 - Feb 2024 |
| Brink Therapeutics | Paris, France | Programmable recombinases |
| Onconaut Therapeutics | Aurora, CO | Precision medicines against molecular targets promoting tumor progression |
| Immune Pharmaceuticals | , | Filed Chapter 11 Bankruptcy, Feb 2019 |
| Kaleido Biosciences | , | Shut down Apr 2022 |
| Fluart Innovative Vaccines | Pilisborosjenő, Hungary | Vaccine, Small Molecule, Biologics CDMO |
| Tacit Therapeutics | South SF, CA | RNA trans-splicing therapies for brain diseases |
| NeurogesX | , | Sold off product to Acorda, Folded? |
| BroadPharm | San Diego, CA | PEG & Biochemical Reagents |
| Stevanato Group | Piombino-Dese, Italy | Drug Delivery, Drug Packaging, Consumable |
| Gordion BIoscience | Cambridge, MA | Tumor Identification for Drug Targeting |
| Gubra | Hørsholm, Denmark | Preclinical Contract Research |
| Ortho Clinical Diagnostics | , | Acquired by Quidel, Dec 2021, $6B |
| , | Website down Dec 2025 - Apr 2026 | |
| Sinovant Sciences | , | Website down Apr 2022 - Aug 2022 |
| Elix | Tokyo, Japan | AI Drug Discovery |
| Gan & Lee Pharmaceutical | Beijing, China | Biosimilars |
| Abcombi Biosciences | , | Website down Jul 2022 - Oct 2022 |
| AEGEA Medical | , | Acquired by CooperSurgical, Feb 2021 |
| Bayer | Leverkusen, Germany | Biotech / Pharma / Chemical Giant |
| Autonomous Medical Devices | Santa Ana, CA | POC Molecular Diagnostics |
| ONFAB | Albacete, Spain | Custom-designed, single-use and retrofit flexible isolators |
| Medasense Biometrics | Ramat Gan, Israel | Pain assessment technology |
| , | Website down Dec 2025 - Apr 2026 | |
| NexusPharma | , | Acquired by Genesis Biotechnology Group, Jun 2019 |
| Vault Pharma | , | Not registered in CA, Aug 2025; No news 2020 - Sep 2025 |
| Aerium Therapeutics | , | Shut down Jul 2024 |
| Sherlock Biosciences | Newton, MA | Molecular Diagnostics |
| Kinamed | Camarillo, CA | Implants, Surgical Tools |
| SuperX | , | Gone |
| Bioperfectus | Shanghai, China | Nucleic Acid Extraction |
| Scantibodies Laboratory | Santee, CA | Diagnostics, Medical Tests |
| Aiosyn | Nijmegen, Netherlands | AI Pathology Software |
| , | Renamed Verge Labs, May 2026 | |
| Neovii Biotech | Rapperswil, Switzerland | Stem Cell Therapy, Biologics |
| BrightWater Medical | , | Acquired by Merit Medical, Sep 2019, $50M |
| Avrin | Liverpool, UK | Clinical Research |
| Oncos Therapeutics | , | Acquired by Oncos Therapeutics, Jun 2015 |
| Ultima Genomics | Newark, CA | High-throughput, low-cost sequencing platform |
| SyntheX | San Francisco, CA | Discovery of treatments for undruggable proteins |
| Echosens | Paris, France | Live Diagnostic Technologies, Data Management Software |
| PharmaDerm | , | Part of Sandoz |
| Pharmaceutics International | Hunt Valley, MD | Contract Development & manufacturing |
| Ascendia Pharmaceutical Solutions | North Brunswick, NJ | Specialty Pharmaceuticals, Drug Delivery, Contract Manufacturing |
| Cullgen | San Diego, CA | Protein Degradation Technology |
| Atomic AI | South SF, CA | AI-based RNA Drug Discovery |
| Vitalli Bio | , | Website down Feb 2025 - Jul 2025; Aditum Bio company |
| Celdara Medical | Lebanon, NH | Cellular therapy, diagnostics |
| Biocell Laboratories | , | Website taken over Aug 2020 |
| Eligo Bioscience | Paris, France | Protein-based nanodelivery vectors, bacteriophages |
| Xintela | Lund, Sweden | Diagnostics, Stem Cells |
| Bayhill Therapeutics | , | Wound Down and Assets acquired by new-incarnation of Tolerion |
| Myriad Genetics | Salt Lake City, UT | Molecular Diagnostics |
| Microbion | Bozeman, MT | Biofilm prevention drugs / coatings |
| Nordic Nanovector | , | Reverse Merged with Thor Medical, Jun 2023; Terminated development, Jul 2022 |
| Precision BioLogic | Dartmouth, NS | Frozen diagnostic products for hemostasis laboratories |
| Syrrx | , | Acquired by Takeda, Feb 2005, $270M |
| OBP Medical | , | Acquired by CooperSurgical, May 2021, $60M |
| RxGen | , | Renamed Virscio, Jan 2020 |
| , | Pandemic era government spongers | |
| Bioarray Therapeutics | , | Shut down Apr 2017 |
| OncoQuest | , | Website down Aug 2020 - Feb 2021; co-located with parent Quest PharmaTech |
| bespark*bio | Vienna, Austria | Consulting |
| West Pharma | St. Petersburg, FL | Pharmaceutical Supplier |
| Atlantia Clinical Trials | Cork, Ireland | Clinical Sites, Recruiting |
| Pathologica | , | No website, Aug 2018. Location houses many biotechs |
| Femtogenix | , | Renamed Pheon Therapeutics, Aug 2022 |
| BlueSky Vaccines | , | Renamed BlueSky Immunotherapies |
| Flagship Biosciences | Broomfield, CO | Biomarker Data Services |
| Ingenza | Penicuik, UK | Contract Manufacturing |
| Carpathian Research Group | Ivano-Frankivsk, Ukraine | Contract Research & SMO conducting and supporting clinical trials of study drugs and medical devices |
| Tarix Orphan | , | Became Constant Pharmaceuticals, Jan 2017 |
| Astra | , | Merged with Zeneca to form AstraZeneca 1998 |
| Librede | , | Acquired by Lygos, Jan 2020 |
| Vaxenta Biotechnologies | , | Run by a lab tech out of his house, no product info on website |
| Mitodys Therapeutics | , | Shut Down Jun 2022 |
| Ascent Pharmaceuticals | Centril Islip, NY | Generics |
| RhytMedix | Mount Laurel, NJ | Wearable Cardiac Monitor |
| Xycrobe Therapeutics | , | Acquired by Crown Laboratories, May 2019 |
| Belief BioMed | Shanghai, China | AAV-delivered Gene Therapies |
| Symbiotic Research | Mount Olive, NJ | Contract Research |
| Baergic Bio | , | Acquired by Avenue Therapeutics, Nov 2022 |
| Hopstem Biotechnology | Princeton, NJ | Cell Therapies |
| DV Biologics | , | Closed down after being convicted of Federal & CA state violations |
| Advanced BioAnalytical Services | , | Renamed Advion Biosciences |
| Fujirebio Diagnostics | Sunnyvale, CA | Biomarkers |
| Breathe Biologics | , | not a registered business in CA, Feb 2025 |
| Metabolon | Morrisville, NC | Diagnostics & Services |
| Viant Medical | Indianapolis, IN | Contract Medical Devices |
| Osteal Therapeutics | Dallas, TX | Drug-device combination for joint infection prevention |
| Tunitas Therapeutics | , | Website Gone Oct 2017 |
| Tonix Pharmaceuticals | Frederick, MD | CNS Disorders |
| AnchorDx | Guangzhou, China | High-throughput sequencing platform |
| |
Kansas City, KS | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Oncogene Science | , | Acquired by Nuclea Biotechnologies |
| Diadem Biotherapeutics | Torrance, CA | Exosome Immunotherapy |
| HTG Molecular Diagnostics | , | Website down Feb 2025; Chapter 11 Bankruptcy, Jun 2023 |
| Maine Standards Company | , | Acquired by LGC, renamed LGC Main Standards, Nov 2015 |
| HumOrigin | , | Website down Dec 2020 - May 2021 |
| Allon Therapeutics | , | Assets acquired by Paladin Labs, Jun 2013 |
| Collagen Matrix | , | Renamed Regenity Biosciences, Mar 2023 |
| Dishman Specialty Chemicals | Ahmedabad, India | Small Molecule Outsourcing |
| Genesis Therapeutics | Burlingame, CA | AI Drug Discovery |
| Geneuity Clinical Research Services | , | Part of Molecular Pathology Laboratory |
| Infinity BiologiX | , | Renamed Sampled, Apr 2022 |
| Veraxa Biotech | Heidelberg, Germany | Microfluidics-based technologies for functional screening of antibodies |
| PGXHealth | , | Renamed Trovis Pharmaceuticals, Feb 2011 |
| Sloning Biotechnology | , | Bought by MorphoSys, Oct 2010, $26.5M |
| Amathus Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Centauri Therapeutics | Cheshire, UK | Alphamers |
| Synthaverse | Lublin, Poland | Small molecule for cancer/infectious disease; various serums/reagents |
| Cosette Pharmaceuticals | South Plainfield, NJ | Generics |
| NitricGen | , | Website down Feb 2021 - Sep 2021 |
| , | Shell Acquired; Strategic Alts, Dec 2024 | |
| Evergen | West Lafayette, IN | Comprehensive portfolio of allograft and xenograft biomaterials |
| Stryker | San Jose, CA | Medical Devices |
| Compucyte | , | Sold Assets to Thor Labs |
| Noxopharm | Castle Hill, Australia | Small Molecules |
| Alcami | Wilmington, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Teleflex Medical | Varedo, Italy | Surgical and Medical Devices |
| GenomeMe | Richmond, BC | Molecular Diagnostics |
| Seres Therapeutics | Cambridge, MA | Microbial drugs to counteract antibiotic side effects |
| BioChain | Newark, CA | Sample Preparation |
| Lifotronic Technology | Shenzhen, China | IVD, Respiratory Devices, Wound Care, Pain Management |
| Advena | Bromsgrove, UK | Medical Device Regulatory Consulting |
| Aptus Endosystems | , | Acquired by Medtronic, Jul 2015, $110M |
| EMKinetics | , | Seems inactive Feb 2021 |
| Entest Biomedical | , | Website gone, Apr 2018. Company CA FTB suspended |
| Immunova Therapeutics | Monrovia, CA | Cancer Immunotherapy |
| Cimeio Therapeutics | Basel, Switzerland | Hematopoietic stem cell transplantation and adoptive cell therapies |
| RaySearch Laboratories | Berlin, Germany | Cancer Research Software |
| Hameln Pharmaceutical | Hameln, Germany | Generic Injectables, APIs |
| , | Website down Jun 2025 - Dec 2025 | |
| Thesan Pharmaceuticals | , | Gone May 2019 |
| Corinth MedTech | , | Website down Sep 2023; Did not submit annual report in 2022 or 2023 |
| xFOREST Therapeutics | Kyoto, Japan | RNA drug optimization |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Bionika Pharmaceuticals | Skopje, North Macedonia | Small Molecules |
| MGI Americas | Shenzhen, China | Sequencing instruments, reagents, and related products |
| TTP Labtech | , | Renamed SPT Labtech |
| GeneFab | Alameda, CA | Gene Therapy Services |
| Kytopen | Cambridge, MA | Gene-modified Cell Therapies |
| Charles River Laboratories | Cologne, Germany | Research Animal Models and Preclinical Research |
| AlveoliX | Bern, Switzerland | Organ-on-a-chip |
| Sideris Pharmaceuticals | , | Terminated trial, gone 2015 |
| Autoscribe Informatics | West Lakes, Australia | LIMS/Laboratory Software & Services |
| SparX Biopharmaceutical | Mount Prospect, IL | Antibody Therapies |
| Ergomed | Cologne, Germany | Clinical Research |
| Amide Pharmaceutical | , | Acquired by Actavis, Jul 2005 |
| Tute Genomics | , | Acquired by PierianDx, Oct 2016 |
| Yinuoke | , | Website down Jun 2024 - Sep 2024 |
| Deka Biosciences | Germantown, MD | Engineered Therapeutic Proteins |
| , | Acquired by MasterControl, Mar 2025 | |
| SocraTec R&D | Oberursel, Germany | Clinical Development Servies |
| Stromedix | , | Bought by Biogen Idec 2012 |
| PRU | Amman, Jordan | Bioequivalence, Clinical Trials, Bioanalytical |
| Paion | Aachen, Germany | Specialty Pharmaceuticals |
| Cell Theranostics | , | Website down Jan 2023 - Jul 2023; fka Cell Point |
| Inform Genomics | , | Website Gone Nov 2018 |
| Health-Chem Diagnostics | , | Acquired by PL Developments, Jul 2017 |
| CytRx | , | Renamed LadRx Sep 2022 |
| Genometry | , | Shut down Dec 2019 |
| Laurimed | , | Sole product sold to Southmedic, Dec 2017 |
| Salgomed | , | Shut down Apr 2022 |
| Elephas Biosciences | Madison, WI | 3D imaging and artificial intelligence to predict cancer therapy effectiveness |
| CXL Ophthalmics | , | Renamed Epion Therapeutics, Jul 2023 |
| Xbrane Biopharma | Solna, Sweden | Protein & Vaccine Production Technology |
| Tandem Therapeutics | Schlieren, Switzerland | Fibrosis Treatments |
| Singula Bio | Oxford, UK | Novel neoantigen-based cell therapies for patients with solid tumors |
| Celleration | , | Acquired by Alliqua Biomedical, Jun 2015, $30.4M |
| BioChemics | , | Charged with fraud by SEC. Not sure this company is legit anymore |
| Simpirica Spine | , | Became Empirical Spine |
| Cutia Therapeutics | Shanghai, China | Drug Reformulations |
| Hamilton medical | Bonaduz, Switzerland | Mechanical Ventilators |
| CereScan Corp | , | Renamed CereHealth |
| Moerae Matrix | , | Doesn't seem active Dec 2021, no updates since 2015 |
| Cromos Pharma | Portland, OR | Clinical Research |
| Thallion Pharmaceuticals | , | Bought by Taro Mar 2017; Bought by Bellus Health, Aug 2013 |
| BaseCure Therapeutics | , | |
| Sublimity Therapeutics | , | Website down Apr 2022 - Aug 2022 |
| BioMarin Pharmaceutical | São Paulo, Brazil | Biologics |
| NeuroPace | Mountain View, CA | Implantable Neurological Treatments |
| Carbogen Amcis | Hunzenschwil, Switzerland | Drug Development & Commercialization |
| Bridge Informatics | Cambridge, MA | Genomic Data Services |
| Cahaba Pharmaceuticals | , | Gone 2015? |
| MyMD Pharmaceuticals | , | Renamed TNF Pharmaceuticals, Jul 2024 |
| Twelve Bio | , | Acquired by Ensoma, Feb 2023 |
| Celsius Therapeutics | , | Acquired by AbbVie, Jun 2024, $250M; fka Cellular Ecosystems Therapeutics |
| Empirica Therapeutics | , | Acquired by Century Therapeutics, Jun 2020 |
| Cytopeia | , | Acquired by BD, May 2008 |
| Caldera Pharmaceuticals | , | Renamed XRpro Sciences, Dec 2014 |
| General Oncology | Brookline, MA | Cancer Therapies |
| Green Cross | , | Renamed GC Pharma |
| Invectys | Paris, France | DNA Vaccine |
| PPD | Morrisville, NC | Contract R & D, Consulting |
| AorTx | , | Acquired by Hansen Medical, Nov 2007, $4.5M |
| Nitto Avecia Pharma Services | Irvine, CA | Pharma Development |
| Metrics Contract Services | , | Acquired by Catalent, Aug 2022, $475M |
| Radimmune Therapeutics | , | Website down Jun 2023 - Nov 2023, business filings late 2020-2023 |
| Nova Biomedical | Norwood, MA | Lab instruments |
| Cole-Parmer | St. Neots, UK | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| ModMab Therapeutics | , | Website down Dec 2024 - Mar 2025 |
| Pace | San German, PR | Analytical Testing, CDMO |
| Eco Quest | , | Now Cynata Therapeutics |
| Fibrocell Science | , | Acquired by Castle Creek Pharmaceuticals, Dec 2019; fka Isolagen |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| MindSet Rx | , | One guy, nothing going on, established 1991 |
| Tanvex BioPharma | San Diego, CA | Biologics Services, CDMO |
| Basepair | New York, NY | Bioinformatics Software Platform for Genomics Data Analysis |
| , | Acquired by Source BioScience, Apr 2025 | |
| Sagitta Biotech | , | Website inactive Aug 2019 - Aug 2020, Ceo wouldn't respond |
| MockV Solutions | , | Acquired by Maravai LifeSciences, Mar 2020 |
| PulseMedica | Edmonton, AB | Vitreoretinal Screening |
| iScience Interventional | , | Acquired by Ellex, Jan 2014 |
| , | Website down May 2025 - Sep 2025 | |
| argenx | Boston, MA | Antibody therapies |
| OptraScan | San Jose, CA | Digital Slide Scanners, Software |
| Alveolus | , | Assets acquired by Merit Medical, Mar 2009 |
| Sotera Wireless | , | Renamed Sotera Digital Health |
| HarkerBIO | , | Shut down Apr 2019 |
| Spectrum Laboratories | , | Bought by Repligen, Aug 2017, $359M |
| Articulate Technologies | , | Renamed Speech Buddies, Dec 2015 |
| Beijing Tide Pharmaceuticals | , | Website down Jan 2025 - Jul 2025 |
| Peptonic Medical | Stockholm, Sweden | OTC Vaginal Atrophy Treatment |
| Dow Pharmaceutical Sciences | , | Bought by Valeant Dec 2008, Wound down late 2013 |
| Medigene | Planegg-Martinsried, Germany | Personalized T cell-based immunotherapies |
| AstraZeneca | Gaithersburg, MD | Small Molecules, Vaccines, Biologics |
| , | Website down Aug 2025 - Jan 2026 | |
| LifeScience PLUS | Mountain View, CA | Wound care |
| Spaltudaq | , | Renamed Theraclone Sciences 2009 |
| Eyevensys | , | Renamed PulseSight Biosciences, Feb 2024 |
| , | Website down Mar 2026; Not registered in CA, Mar 2026 | |
| CardioNet | , | Renamed BioTelemetry, Jul 2013 |
| bioMerieux | Hazelwood, MO | Diagnostics |
| Midas Pharma | Ingelheim, Germany | API Middleman |
| Flen Health | Kontich, Belgium | Wound Healing Products |
| Emerge Diagnostics | , | Rebranded as Precision Motion Health, Sep 2024 |
| Agennix | , | Bankrupt and liquidated, May 2013 |
| IntelGenx | , | Renamed Nualtis, Jun 2025 |
| Lexeo Therapeutics | New York, NY | Gene Therapy |
| , | Shut down Oct 2024 | |
| AstraZeneca | Wilmington, DE | Small Molecules, Biologics |
| Kopran | Mumbai, India | Contract Manufacturing, APIs |
| Pharos iBio | Anyang-si, Korea | AI Drug Discovery |
| Perseon Medical | , | Assets bought by Medlink, Aug 2016, $4M; fka BSD Medical |
| Maxis Clinical Sciences | Pune, India | Clinical Research Consulting |
| Scanwell Health | , | Acquired by BD, Dec 2021 |
| Allez Health | Carlsbad, CA | Biosensors |
| Rontis | Larissa, Greece | Generics, Contract Manufacturing |
| Digital Bio Pharm | , | Website down Apr 2019 - Aug 2019 |
| Hypervision Surgical | London, UK | AI-powered hyperspectral imaging systems |
| ECI Biotech | , | Gone 2016 |
| Repco Development Technologies | , | Renamed 3Dispense |
| Seragon Pharmaceuticals | , | Acquired by Genentech, Aug 2014 $725M + $1B Milestones; Acquired by JNJ Aug 2013 $650M + $350 Milestones |
| Cole-Parmer | Vernon Hills, IL | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| SNIPR BIOME | Copenhagen, Denmark | CRISPR for microbiome management, genetically-modified bacteriophages |
| Salus Bio | Shenzhen, China | Sequencing Platform, Spatial Transcriptomics |
| Protelight Pharmaceuticals | Jiangyin, China | Peptide and Small Molecules Therapies |
| Creative Enzymes | Shirley, NY | Enzymes |
| MacuClear | , | Website gone Jan 2019 |
| Pearl Therapeutics | , | Acquired by AstraZeneca Jul 2013, $560M+$450milestones |
| Neoprobe | , | Changed name to Navidea Biopharmaceuticals, Jan 2012, Acquired by Devicor |
| AGA Medical | , | Acquired by St. Jude Medical, Oct 2010, $1.3B |
| Pertinax Pharma | , | Website Down Jan 2022 - Jul 2022 |
| AtriCure | Minnetonka, MN | Cardiovascular Devices |
| Lyman Biopharma Consulting | , | Switched to writing |
| Verlyx Pharma | , | Acquired by Odan Laboratories, Dec 2018; fka Oncozyme Pharma, McGill spinout |
| Axerion Therapeutics | , | Changed name to ReNetX Bio, Jul 2017 |
| MAP Pharmaceuticals | , | Acquired by Allergan 2013 |
| Liminal BioSciences | Sawston, UK | Small Molecules, Biologics, Protein Technologies |
| Ribomic | Tokyo , Japan | Aptamers |
| Genelex | , | Acquired by Invitae, Mar 2020 |
| Curative Medical | , | Acquired by ResMed, Oct 2015 |
| OD-OS | Teltow, Germany | Retinal Laser |
| Integra LifeSciences | Princeton, NJ | Medical Devices |
| Hologic | Vienna, Austria | Diagnostic, Imaging |
| Pharmapack Stade | Stade, Germany | Blister Packaging |
| Wilson Therapeutics | , | Acquired by Alexion, May 2018, $855M |
| Sensile Medical | , | Acquired by Gerresheimer, Jul 2019, up to €350M |
| Quark Pharmaceuticals | , | Website down Sep 2021 - Jan 2022 |
| Cytiva | Tokyo, Japan | Medical Devices |
| SimBioSys Biowares | , | Website gone Nov 2019 |
| , | No news 2022 - Mar 2026 | |
| Imagia Canexia Health | , | Website down Jul 2024 - Dec 2024; fka Contextual Genomics |
| Thetawave | Pune, India | Toxicology, Pharma and Device Service |
| Twin Star Medical | , | Did not renew business in MN 2018, Closed per Google Jan 2019; Site down Jan 2019 |
| Amarin | Dublin, Ireland | Small Molecules |
| Worldwide Clinical Trials | Kiev, Ukraine | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Nereus | , | Website Gone late 2013, no info |
| Theranyx | , | Website down Sep 2021 - Jan 2022 |
| Idera Pharmaceuticals | , | Renamed Aceragen Jan 2023 after having earlier acquired it |
| , | Website down Oct 2025 - Feb 2026 | |
| Bioaxis Healthcare | , | Folded into IQVIA, Aug 2023 |
| Axplora | Shanghai, China | Purification Systems |
| Upsher-Smith | Maple Grove, MN | Small Molecules, Generics |
| Beogenomics | , | Acquired by APIS Assay Technologies, Sep 2020 |
| AstraZeneca | Waltham, MA | Small Molecules, Biologics |
| Cambria Pharmaceuticals | , | Website Gone 9-12-13 |
| Signia Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Camena Bioscience | Cambridge, UK | Nucleic acid synthesis technology |
| GABAeron | San Francisco, CA | Stem-Cell Based Therapy for Alzheimer's, Small Molecules |
| Novogen | , | Renamed Kazia Therapeutics, Nov 2017 |
| Alfacell | , | Now Tamir Biotechnology |
| SSS International Clinical Research | , | Acquired by Optimapharma Group, Dec 2021 |
| Guardion Health Sciences | , | Shut down |
| Oncotherapy Solutions | Bothell, WA | Small Molecules, Drug Conjugates |
| Topigen Pharmaceuticals | , | Acquired by Pharmaxis, 2010 |
| MicroPort | Arlington, TN | Medical Devices |
| Raritan Pharmaceuticals | East Brunswick, NJ | Contract Drug Manufacturing |
| Sharp Edge Labs | , | Renamed Sharp Therapeutics, Feb 2021 |
| Trevena | Chesterbrook, PA | GPCR-targeted Drug Discovery |
| LakeShore Biopharma | Beijing, China | Vaccines |
| 3B Pharmaceuticals | Berlin, Germany | Peptides |
| Insight Genetics | , | Acquired by Oncocyte, Feb 2020 |
| Elucid | Boston, MA | Arterial Analysis Software |
| Arbutus Biopharma | Warminster, PA | RNAi |
| GlySens | , | Bankrupt Nov 2022 |
| Rubix Device | , | Website gone, Aug 2017 |
| Novassay | , | Website down Mar 2025 - Aug 2025 |
| Dexorgen | Rockville, MD | Cell lines, dyes, services |
| Beiwe Pharma | , | CA business filings late Nov 2022 - Aug 2024 |
| Sea Pharmaceuticals | , | Founded 2013, Seems like one guy, no published progress |
| CorePharma (1) | , | Acquired by Impax Laboratories, Mar 2015 |
| Focus Biomolecules | Plymouth Meeting, PA | Life Science Reagents |
| Oncotelic | , | Merged with Mateon Therapeutics, Apr 2019 |
| Philogen | Sovicille, Italy | Antibody-drug Conjugates |
| Unither Pharmaceuticals | Barretos, Brazil | CDMO |
| Syntrix Pharmaceuticals | Auburn, WA | Small Molecules |
| Pozen | , | Merged with Tribute Pharmaceuticals, Dec 2015, became Aralez Pharmaceuticals |
| Boost Neuroscience | , | Acquired by Gate Neurosciences, Feb 2025 |
| Renovis Surgical | , | Major assets bought by Kyocera Medical, Jan 2019 |
| Cytoville | , | Renamed Cytek Biosciences, Aug 2015 |
| Oncolytics Biotech | Calgary, AB | Human Reovirus Delivery |
| Senzer Pharmaceuticals | , | Shutting down Jan 2021 |
| Astion Pharma | , | Products acquired by Cipher Pharmaceuticals, Feb 2015 |
| Proteom | , | Acquired by Amura Ltd |
| AOP Orphan Diseases | Bucharest, Romania | Orphan disease treatments |
| VERTIS Biotechnologie | , | Shut down, Dec 2022 |
| Coloplast | Minneapolis, MN | Wound care, surgical, bladder, bowel devices |
| Combinati | , | Acquired by Thermo Fisher, Oct 2021 |
| Applied Spectral Imaging | Carlsbad, CA | Digital Pathology |
| |
Tyrone, PA | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Bayou Biolabs | , | Exceptionally dated website Nov 2019 |
| Sourcia | , | Acquired by Alira Health, Apr 2022 |
| Venari Medical | , | Renamed Invera Medical, Feb 2022 |
| Sension | Augsburg, Germany | Immunoassays, Diagnostics |
| Theranostics Health | , | Merged into Avant Diagnostics, Mar 2016 |
| Spirita Oncology | , | No news Aug 2020 - Jan 2025 |
| Immutep | Berlin, Germany | Cell therapies & antibodies |
| AbVacc | Rockville, MD | Vaccines, Biologics, Monoclonals |
| Cyclarity Therapeutics | Novato, CA | 7-ketocholesterol Targeting |
| Stimgenics | , | Acquired by Medtronic, Jan 2020 |
| Privail | , | Business inactive in CA, likely didn’t make it out of incubator |
| Karma Oncology | Glasgow, UK | Oncology Clinical Development |
| Akero Therapeutics | South SF, CA | NASH therapy |
| Aesgen | , | Acquired by MGI Pharma, Sep 2004 |
| Vara | Berlin, Germany | AI-powered software for early breast cancer detection |
| Jiuzhou Pharma | Yancheng, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Contract Pharmacal | Hauppauge, NY | Contract Manufacturing, Small Molecules |
| PL BioScience | Aachen, Germany | Animal-free cell culture supplements |
| Nutcracker Therapeutics | Emeryville, CA | Precision mRNA manufacturing platform |
| Aquila Biopharmaceuticals | , | Acquired by Antigenics, Aug 2000, $40M |
| Target Health | , | Merged with Clinipace, Apr 2021 |
| BeneChill | , | Assets purchase by BrainCool, Oct 2016 |
| SI-BONE | Gallarate, Italy | Sacroiliac joint fusion device |
| Excubio Pharmaceuticals | , | Website down Jan 2020 - May 2020, never registered as business in MA |
| Alvotech | Reykjavik, Iceland | Biosimilars |
| Cenetron Diagnostics | , | Acquired by Versiti Blood Center, Jul 2019 |
| Priovant Therapeutics | Durham, NC | Autoimmune Therapies |
| CYPrus Therapeutics | , | No website Nov 2018 - Feb 2024 |
| Genencor | , | Bought by DuPont |
| Scale Biosciences | San Diego, CA | Single-Cell Spatial Biology Tech |
| Foresight Biosciences | , | Website down Apr 2025 - Sep 2025 |
| , | Filings late Jan 2024 - Jan 2026; Unknown Modalities, Jul 2021 - Jun 2025; No news 2012 - Jan 2026 | |
| Exalys Therapeutics | , | Shut down Nov 2022 |
| Highland Therapeutics | , | Took subsidiary name - Ironshore Pharmaceuticals |
| Angel Biotechnology | , | Bankrupt, 2013 |
| Genfit | Loos, France | Drug Discovery |
| AeenaDx | , | Merged with NowDx, Apr 2023 |
| BioAlliance Pharma | , | Merged with TopoTarget to become Onxeo |
| Provecs Medical | , | Gone Nov 2019 |
| Ona Therapeutics | Barcelona, Spain | ADC Cancer Therapies |
| Albireo Pharma | , | Acquired by Ipsen, Mar 2023; Merged with Biodel Nov 2016; Spun out of AstraZeneca in 2008 |
| , | Founder, Principal gone Sep 2024 | |
| Graceway Pharmaceuticals | , | Bought by Medicis out of Bankruptcy |
| MiroBio | , | Acquired by Gilead, Sep 2022 |
| PEAR Therapeutics | , | Chapter 11 Bankruptcy, Apr 2023 |
| Immodulon Therapeutics | , | Website suspended Feb 2025 - Jun 2025 |
| Shaman Pharmaceuticals | , | Stopped working on drugs Feb 1999 |
| Gravity Diagnostics | Covington, SS | Diagnostic Lab |
| OriCiro Genomics | , | Acquired by Moderna, Jan 2023, $85M |
| Star Therapeutics | South SF, CA | Antibody Therapeutics |
| Heraeus Medical | Unanderra, Australia | Medical Devices |
| Spinifex Pharmaceuticals | , | Bought by Novartis, $200M + milestones, Jul 2015 |
| Frontier Global Sciences | , | Acquired by eurofins, Sep 2012 |
| toSense | , | Acquired by Baxter, Jun 2020 |
| Deciphera Pharmaceuticals | Lawrence, KS | Small Molecules |
| Theralase Technologies | Toronto, ON | Photo Dynamic Compounds |
| Theracle | , | Website gone Nov 2019 - Oct 2020 |
| Glycotex | , | Assets sold by parent company, Aug 2012 |
| Full-Life Technologies | Shanghai, China | Nuclear Medicines |
| ILSBio | , | Merged with BioreclamationIVT, Jul 2015 |
| Lab901 | , | Bought by Agilent |
| Housey Pharmaceutical Research Laboratories | Southfield, MI | Small Molecules |
| Clinisys | Tucson, AZ | LIMS Platform |
| AngioSafe | San Jose, CA | Cardio Intervention Devices |
| AmplifyBio | , | Shut down Apr 2025 |
| OncoGenex Pharmaceuticals | , | Merged with Achieve Life Sciences, took Achieve name, Aug 2017 |
| Immunogen (1) | , | Renamed ImmunogenX |
| Viant Medical | Chaumont, France | Contract Medical Devices |
| Melinta Therapeutics | Parsippany, NJ | Small Molecule Discovery |
| Vista Therapeutics | , | Website down Mar 2021 - Aug 2021 |
| Tara Immuno-Oncology | , | Website gone, Nov 2017 |
| Metis Pharmaceuticals | , | Renamed METiS Therapeutics, Feb 2022 |
| LabConnect | Johnson City, TN | Lab Services |
| Ergomed | Sarajevo, Bosnia & Herzegovina | Clinical Research |
| Exelixis | Alameda, CA | Small Molecules |
| IDDI | Ottignies-Louvain-la-Neuve , Belgium | Regulatory Statistics, Clinical Data Science |
| Sable Bio | London, UK | AI-powered platform for drug safety assessment |
| Tortugas Neuroscience | Framingham, MA | Neurological Therapies |
| Chiromics | , | Website now a penny stock shill |
| Predicine | Hayward, CA | Liquid Biopsy |
| SanegeneBio | Woburn, MA | siRNA Drug Discovery |
| Montigen Pharmaceuticals | , | Acquired by SuperGen, Apr 2006, $18M |
| Helix | San Mateo , CA | Genetic Testing |
| Vectura | , | |
| Lenetix | , | Acquired by Bio-Reference Labs 2010 |
| |
Groningen, Netherlands | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Bioanalysis for small and large molecules and gene therapy. |
| TangenX | , | Acquired by Novasep 2006, sold to Repligen, Dec 2016, $39M |
| Emavant | , | No website Nov 2019 - Aug 2021, seems to be part of Roivant now |
| AMAG Pharmaceuticals | , | Acquired by Covis Pharma, Nov 2020 |
| Signum Dermalogix | , | Signum Biosciences spinout, now redirected to parent page |
| , | Insolvent, acquired by FRIED, Nov 2025 | |
| Quantamerix | , | No info since 2012, never registered in MA |
| Salix Pharmaceuticals | Bridgewater, NJ | Specialty Small Molecules, Gastroenterological |
| Savira Pharmaceuticals | , | Website gone Feb 2020 - Aug 2021 |
| Azurity Pharmaceuticals | Woburn, MA | Compounding Kits |
| Prestige BioPharma | Singapore, Singapore | Biologics, Biosimilars |
| , | Website down Aug 2025 - Jan 2026 | |
| Unchained Labs | Pleasanton, CA | Tools for biologics research & development |
| Techne | , | Part of R&D Systems |
| General Proximity | San Francisco, CA | Induced-Proximity Medicines |
| Aquyre Biosciences | , | Renamed CellTivity, Mar 2025 |
| CHO-plus | South SF, CA | Engineered mammalian cell lines and transfection methods for vastly improved therapeutic protein production and sialylation |
| IvWatch | Newport News, VA | IV infiltration detection |
| Cullgen | Shanghai, China | Protein Degradation Technology |
| Trillium Diagnostics | , | Closed Jul 2016 |
| ICQ Consultants | , | Acquired by Ellab, Nov 2022 |
| BioType | Dresden, Germany | Molecular Diagnostics, Contract Manufacturing, Contract Development, OEM |
| BALT | Irvine, CA | Products for the interventional access and treatment of neurovascular diseases |
| Levo Therapeutics | , | Website down Oct 2023 - Mar 2024 |
| Blue Torch Medical | , | Website down Feb 2020 - Jun 2020 |
| Bactobio | London, UK | Harvesting valuable metabolites from biological dark matter |
| OvaGene Oncology | , | Gone Feb 2020 |
| InNeuroCo | , | Acquired by Integer, Oct 2023 |
| Distalmotion | Epalinges, Switzerland | Surgical Robots |
| Nivien Therapeutics | , | Shut down after trial failure 2018 |
| InSite Vision | , | Acquired by Sun pharma Sep 2015 |
| , | Website down Sep 2025 - Dec 2025; Filings late Dec 2024 - Dec 2025 | |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Noetik | South SF, CA | AI Cancer Immunotherapy Discovery |
| PMG Research | , | Now Acellacare |
| , | ||
| Ferring Pharmaceuticals | Mexico City, Mexico | Oral Liquid Manufacturing |
| NewBiologix | Epalinges, Switzerland | Cell Line Engineering for Cell and Gene Therapy |
| Ophthalmic Sciences | , | Website down Nov 2023 - Mar 2024 |
| Accellent | , | Acquired Lake Region Medical $390M Mar 2014, took on their name |
| Hologic | Beijing, China | Diagnostic, Imaging |
| Equillium | La Jolla, CA | Monoclonal Antibody Therapies |
| Virapur | , | Acquired by Microbiologics, 2017 |
| , | Acquired by Azurity Pharmaceuticals, Mar 2025 | |
| Nybo Therapeutics | , | Founder already done in 2018 after one year |
| Enliven Therapeutics | Boulder, CO | Cancer Treatments |
| AstraZeneca | South SF, CA | Small Molecules, Vaccines, Biologics |
| Aspire Therapeutics | , | Merged with Covalution Bioscience to become Acerta Pharma |
| Lifecore Biomedical | Chaska, MN | Integrated parenteral CDMO & sodium hyaluronate manufacturer |
| API Pharma Tech | North Brunswick, NJ | Generics, APIs |
| Arraystar | Rockville, MD | Microarrays |
| MBX Biosciences | Carmel, IN | Hormone Analogues for Rare Endocrine Diseases |
| Activated Cell Therapy | , | Changed name to Dendreon |
| RadiusXR | Pleasanton, CA | Vision Testing Device |
| DL Develop | , | Website gone, Dec 2018 |
| 3Derm Systems | Coralville, IA | AI to automate Dermatological Care |
| Dr Reddy’s CPS | , | Rolled into Aurigene Pharmaceutical Services, Jun 2020 |
| Cirtec Medical | Brooklyn Park, MN | Contract Medical Devices |
| Cornerstone Robotics | Hong Kong, China | Surgical Robots |
| Amgen | Mississauga, ON | Small Molecules, Biologics |
| Valogic Bio | Frederick, MD | GxP compliance solutions for life sciences and biotech companies |
| Cilatus Biopharma | Dublin, Ireland | CMC Consulting |
| Cognesy Therapeutics | , | Website down Jun 2023 - Nov 2023 |
| Getinge | Feldkirchen, Germany | Medical Technology |
| Ibex Medical Analytics | Tel Aviv, Israel | Cancer Diagnostics |
| AviadoBio | London, UK | Gene Therapies for neurodegenerative |
| Qvella | , | Website down Sep 2024 - Feb 2025 |
| Allay Therapeutics | San Jose, CA | Multi-week Localized Pain Management |
| Auris Medical | , | Renamed Altamira Therapeutics |
| IntraBiotics Pharmaceuticals | , | Changed name to Ardea Biosciences 2006 |
| MicroCam | , | Shut down 2015? |
| Cellenion | Tempe, AZ | Single Cell Testing |
| Delpharm | Orléans, France | Contract Manufacturing |
| Syneos Health | Newtown, PA | Clinical Development |
| Dioseve | Tokyo, Japan | Assisted reproductive technology using oocytes derived from iPS cells |
| Archer Pharmaceuticals | , | No news, Feb 2018 - Dec 2025 |
| Bullet Biotechnology | , | Dissolved Sep 2017 |
| Bastion Therapeutics | , | Shut down |
| Jennerex | , | Acquired by SillaJen, Nov 2013, up to $150M |
| Orchid Orthopedic Solutions | Chelsea, MI | Contract Medical Device Work |
| Vascular Biogenics | , | Now VBL Therapeutics |
| Provia Labs | , | Website down May 2023 - Dec 2023 |
| Ace Bio-Pharmtech | , | Website inactive, Jul 2014 |
| Patheon | Bourgoin-Jallieu, France | Contract Manufacturing and Development |
| Strekin | , | Website down Sep 2021 - Feb 2022; Sister company of Kinarus |
| Doer Biologics | Hangzhou, China | Biologics |
| JustRight Surgical | , | Renamed Bolder Surgical |
| Pharma Start | , | Merged with H2O Clinical, Aug 2016 to become Firma Clinical Research |
| Heron Therapeutics | Cary, NC | Polymer-Based Delivery |
| Novo Nordisk | West Lebanon, NH | Diabetes, obesity, liver disease and other therapeutic areas |
| , | Website down Jul 2025 - Jan 2026 | |
| Trice Medical | Malvern, PA | Illumination device, handheld joint imaging |
| 3PrimiR | , | Funded in 2009, presumed defunct |
| NuGenerex Diagnostics | , | Website down Nov 2022 - Mar 2023; fka Hema Diagnostics Systems |
| Mobidiag | , | Acquired by Hologic, Jun 2021, $795M |
| SK Pharmteco | La Porte, TX | Small Molecule Development & Manufacturing |
| TransGenRx | , | Bankrupt |
| Peloton Therapeutics | , | Bought by Merck, May 2019, $1.05B + $1.2B Milestones |
| Westlake Genetech | Hangzhou, China | AI-powered Gene Therapy Development |
| Brainomix | Oxford, UK | AI-powered imaging biomarkers to enable precision medicine for better treatment decisions |
| AbbVie | Barceloneta, PR | Contract Manufacturing |
| Cambrex | Karlskoga, Sweden | Small Molecules Research, Development & Manufacturing Services |
| Myrobalan Therapeutics | Medford, MA | Neurological & Psychiatric Therapies |
| Immudex | Fairfax, VA | Diagnostics & Reagents |
| Tvardi Therapeutics | Sugar Land, TX | STAT3 inhibitors |
| NILO Therapeutics | New York, NY | Therapies for autoimmune and inflammatory diseases |
| Quotient Bioresearch | , | Acquired by Pharmaron, Feb 2016 |
| Q2 Solutions | , | Fully acquired by IQVIA, Apr 2021 |
| SANI Membranes | Farum, Denmark | Filtration Technology |
| Starlight Cardiovascular | San Diego, CA | Devices for Congenital Heart Defects |
| Ambryx Biotechnology | , | Dissolved Dec 2018 |
| Fabrus | , | Acquired by Sevion Therapeutics, May 2014 |
| Lectenz Bio | Athens, GA | Glycan Detection Platform & Services |
| AngioSoma | , | Website down Oct 2021 - Mar 2022 |
| Shutt Medical Technologies | , | Acquired by CONMED, 1983 |
| LGC Maine Standards | Cumberland Foreside, ME | Calibration Verification and Linearity |
| Geneticist | , | Website down Nov 2022 - Mar 2023 |
| Salzman Group | , | Acquired by Kalytera, Feb 2021; Residential address May 2021 |
| UCB-Celltech | Slough, UK | Small Molecules, Biologics |
| Velano Vascular | , | Acquired by BD, Jul 2021 |
| Antoxerene | , | Ichor removed from website as of Dec 2021 |
| Exo Therapeutics | Cambridge, MA | Small Molecule Drug Discovery |
| Affivant | , | Part of Roivant |
| Sernova Biotherapeutics | London, ON | Implantable pouch to house cellular therapy |
| UCB Pharma | Smyra, GA | Small Molecules, Biologics |
| Beta Bionics | Irvine, CA | Artificial Pancreas |
| Proclara Biosciences | , | Shut down Aug 2021; fka Neurophage Pharmaceuticals |
| Metrics Inc | , | Renamed Metrics Contract Services |
| Krystal Biotech | Pittsburgh, PA | Gene Therapy |
| Resolution Biomedical | Tustin, CA | Consumable Diagnostic Products |
| Rx3 | , | Now Trius Therapeutics |
| Bar Harbor Biotech | , | Dissolved Jul 2015 |
| BioXell | , | Acquired by Cosmo Pharmaceuticals, Nov 2009 |
| Velsera | Charlestown, MA | Biomedical data analysis platform |
| Cardima | , | Bankrupt Dec 2010 |
| One Codex | Wilmington, DE | Microbiome Sequencing Platform |
| Highlightll Pharmaceutical | Hangzhou, China | Small Molecules |
| ManaT Bio | , | Renamed Clasp Therapeutics, Mar 2024 |
| NeuExcell Therapeutics | Philadelphia, PA | Gene Therapy for Neural Regeneration & Repair |
| Caraway Therapeutics | , | Acquired by Merck, Nov 2023, $610M; fka Rheostat Therapeutics |
| NanoCure | , | Changed name to Avidimer Therapeutics, May 2005 |
| Walden Biosciences | Cambridge, MA | Podocyte-targeting Kidney Disease Treatments |
| Neurimmune | Schlieren, Switzerland | Antibody Therapeutics |
| AvenCell Therapeutics | Dresden, Germany | CAR-T, T cell engaging bispecific antibody |
| |
Hopkinton, MA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Atreus Pharmaceuticals | , | Acquired by Advanced Accelerator Applications, Jan 2015 |
| Convergence Pharmaceuticals | , | Bought by Biogen Idec, Jan 2015, $200M +$475 Milestones |
| BioScreen Testing Services | , | Acquired by ALS Group USA, Feb 2019 |
| Curexsys | , | Dissolving, Jul 2024 |
| DM Bio | , | Renamed STgen Bio, Apr 2022 |
| Nuron Biotech | , | Website down, June-Oct 2015 |
| Cytel | Cambridge, MA | Clinical software, statistical services |
| PharmaLex | Bad Homburg, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Deciphera Pharmaceuticals | Waltham, MA | Small Molecules |
| Bao Pharmaceuticals | Shanghai, China | Enzymes, Antibodies, Formulation, Proteases |
| Initium Therapeutics | , | Website down May 2023 - Dec 2023 |
| SNIBE Diagnostics | Pingshan District, China | Diagnostics |
| Alliance Pharma | , | Renamed Resolian, May 2023 |
| BRT Labs | Morrisville, NC | Immunotoxicology Services |
| Tivorsan Pharmaceuticals | , | Shut down in or before 2020 |
| Zivena | , | Gone |
| Fagus Antibody Services | , | Website down Feb 2025 - Jul 2025 |
| Norgine | Hengoed, UK | Specialty Pharma |
| Vivifi Life Sciences | Bangalore, India | Generics |
| , | Renamed Revr Jan 2026 | |
| OptiKira | , | Website under construction Dec 2022 - Jul 2023 |
| OsteoCentric Technologies | Austin, TX | Mechanical Integration technology for orthopedic and dental implants |
| UCB Pharma | Monheim am Rhein, Germany | Small Molecules, Biologics |
| Leon Nanodrugs | Planegg, Germany | GMP nanoparticle manufacturing |
| M3 Wake Research | Raleigh, NC | Clinical Research |
| ValenTx | , | Website down Jul 2020 - Mar 2021; Not registered in MN Sep 2020 |
| Abrika Pharmaceuticals | , | Acquired by Actavis, Apr 2007 |
| Hardin Scientific | , | Website down Oct 2022 - Apr 2023 |
| BriaCell Therapeutics | West Vancouver, BC | Immunotherapies |
| Crestovo | , | Merged with Finch Therapeutics, Oct 2017 |
| Boston Scientific | Clonmel, Ireland | Medical Devices |
| T-CURX | Würzburg, Germany | Cellular Immunotherapies |
| Orexigen Therapeutics | , | Bankrupt Mar 2018, Assets sold to Nalpropion Pharmaceuticals, Apr 2018, $75M |
| Mission Pharmacal | San Antonio, TX | Small Molecules and Consumer Products |
| Radiant Genomics | , | Acquired by Zymergen, Jan 2018 |
| Intana Bioscience | Planegg, Germany | Assay development, screening and target/hit validation using fluorescence cross-correlation spectroscopy |
| Biotronic | , | Bought by NuVasive, Jul 2016, $98M |
| Tengion | , | Went bankrupt, Mar 2015, bought by two former employees, seem to be rebranded as RegenMedTx |
| Nevro | Redwood City, CA | Stimulation device for back pain |
| Statecs | Yerevan, Armenia | Medical Writing, Clinical Data, Statistical Programming, Regulatory |
| Inova Labs | , | Bought by ResMed, Jan 2016 |
| Syneos Health | Morrisville, NC | Clinical Development |
| AgenT | Paris, France | Early Detection of Alzheimer's |
| Akorn | , | Chapter 7 bankruptcy, Feb 2023 |
| Montana Molecular | Bozeman, MT | Fluorescent Biosensors for Live Cell Discovery |
| CBCC Global Research | Bakersfield, CA | Clinical Services |
| Neon Mind Biosciences | , | Shell acquired by an energy company, Jan 2023 |
| Chinook Therapeutics | , | Acquired by Novartis, Aug 2023, $3.2B; Acquired Aduro Biotech, Oct 2020, for ticker |
| , | Acquired by Arterex, Jun 2023 | |
| bit.bio | Cambridge, UK | Human Cell Therapy Technology |
| BioSpherex | , | Renamed Metabiomics |
| Microbia | , | Renamed Ironwood Pharmaceuticals which later sold of a business unit of the same name to DSM |
| Directed Genomics | , | Website down Dec 2021 - Jul 2022 |
| Abreos Biosciences | , | Website down Jun 2023 - Dec 2023 |
| PluriSelect | El Cajon, CA | Cell Separation |
| Goldfinch Bio | , | Shutting down Jan 2023 |
| Hologic | Liège, Belgium | Diagnostic, Imaging |
| Gemmus Pharma | , | Shut down, Dec 2017 |
| EntreMed | , | Changed name to CASI Pharmaceuticals, Jun 2014 |
| LianBio | , | Winding down Feb 2024 |
| Meraki Pharmaceuticals | , | Associated with Aclipse, CEO left and is only with Aclipse now, so presumed defunct |
| , | Pivoted to blockchain, Sep 2025 | |
| RetroVirox | , | Business filings late, Nov 2022 - Aug 2024; No updates since 2015 as of Mar 2023 |
| Toleranzia | , | Merged into Flerie, Aug 2025 |
| PCI Pharma Services | Tredegar, UK | Contract Manufacturing, Services |
| Spiderwort | Ottawa, ON | Cellulose-based scaffolding to treat spinal cord injuries |
| Quanticate | Hitchin, UK | Clinical Research |
| , | Acquired by IQVIA | |
| PierianDx | , | Merged with Seven Bridges Genomics & UgenTec to become Velsera, Jan 2023 |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Regenica Biosciences | , | Gone Nov 2020 |
| Biosynth | Staad, Switzerland | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Hologic | San Diego, CA | Diagnostic, Imaging |
| Becker Orthopedic | Troy, MI | Joints & Implants |
| KSL Biomedical | Buffalo, NY | Diagnostic Technology |
| , | Shut down Nov 2025 | |
| Adare Pharma Solutions | Vandalia, OH | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Taconic Biosciences | Rensselaer, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Singota Solutions | Bloomington, IN | Contract Development & Manufacturing |
| Afaxys | Charleston, SC | Women's Health |
| Pharmigene | , | Website down Mar 2023 - Dec 2023 |
| Empatica | Cambridge, MA | Seizure Detection |
| Grannus Biosciences | , | Gone |
| Biotechpharma UAB | , | Renamed Northway BiotechPharma |
| Janpix | , | Acquired by Centessa Pharmaceuticals |
| DLRC Group | Garden City, UK | International consulting group, supporting the Pharma & Biotech community |
| Illumina | San Diego, CA | Genomic tools, research products, molecular diagnostics, NGS |
| Rheos Medicines | , | Shut down Dec 2022 |
| Tissium | Paris, France | Synthetic Polymers for Vascular Sealing |
| Fresenius Kabi | Wuxi, China | Contract Manufacturing |
| Array Biopharma | , | Bought by Pfizer, Jul 2019, $11.4B |
| Codagenix | Farmingdale, NY | Live-attenuated vaccine design technology |
| CathWorks | Newport Beach, CA | Catheter Guidance |
| Aumintec | Richmond Hill, ON | DNA/RNA Automation |
| Poolbeg Pharma | London, UK | Developing drugs to sell off |
| Azelon Pharmaceuticals | , | Gone, 2012?; fka Zelos Pharmaceuticals |
| Progen Biotechnik | Heidelberg, Germany | Antibodies, in vitro diagnostics, ELISA, AAV |
| Serendipity Bio | , | Acquired by Arbor Biotechnologies |
| Todos Medical | , | Website down Feb 2024 - Jul 2024 |
| Creative Biogene | Shirley, NY | Genomics and proteomics products and services |
| Ensera | Jelcz-Laskowice, Poland | Device Manufacturing, Pharmaceutical Packaging |
| Synergx | , | Owned by Morphogenesis |
| AMBI Pharmaceuticals | , | Acquired by Neuro-Hitech, Nov 2008 |
| Mitobridge | , | Acquired by Astellas, Nov 2017, $225M + $225M milestones; Formerly Mitokyne |
| , | Acquired by Sino Biopharm, Jul 2025 | |
| 3D Biotek | Warren, NJ | 3D Cell Culture |
| MediLink Therapeutics | Suzhou, China | ADC |
| Beyond Air | Garden City, NY | Nitric Oxide Therapy |
| , | Website down Sep 2025 - Feb 2026 | |
| Kymo Therapeutics | , | Seems like a dead end joint venture |
| Avolynt | , | Acquired by AstraZeneca, Mar 2024, $1.05B; fka BHV Pharma |
| Diassess | , | Renamed Lucira Health |
| HELP Therapeutics | Nanjing, China | iPSC Therapies, Stem Cell Services |
| Pacific BioLabs | Hercules, CA | Analytical Services |
| Zenalux Biomedical | , | Nothing going on 2015-2021, everyone has University jobs |
| Vittamed | , | Renamed Boston Neurosciences, Jul 2018 |
| , | No news 2021 - Apr 2026 | |
| RadioMedix | Houston, TX | Radiopharmaceuticals, Imaging Technology |
| Pristine Bioproduction | , | Not a going concern |
| EndoCellutions | , | Website down Jan 2023 - Jul 2023 |
| AuricX Pharmaceuticals | , | Website gone 2-5-15 |
| AAT Bioquest | Pleasanton, CA | Bioanalytical research reagents and kits; various contract research offerings |
| Dispatch Bio | Philadelphia, PA | Immuno-oncology |
| BioMarin Pharmaceutical | Hong Kong, China | Biologics |
| Kexing Biopharm | Jinan, China | Recombinant Protein Therapeutics |
| Vrex Therapeutics | , | CEO & Founder gone April 2021 |
| ScaleReady | St. Paul, MN | Scalable Cell & Gene Manufacturing |
| Affineti Biologics | , | Funded in 2011, no website in Aug 2021 |
| , | Renamed Alethio Therapeutics | |
| , | 16 years in, CMO is CEO elsewhere Dec 2025; fka Glycoregimmune | |
| , | Website down Jul 2025 - Jan 2026 | |
| NIOX | Oxford, UK | Asthma management device |
| Bakhu Pharma | , | Bankrupt, location sold |
| NRx Pharmaceuticals | Wilmington, DE | Small Molecules |
| Transition Bio | Cambridge, MA | Condensate technology, liquid-liquid phase separation |
| |
Sorocaba, Brazil | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Pylum Biosciences | , | Filings late Nov 2022 - Feb 2025; formed when Avidbiotics split, Nov 2017; co-located with Xyphos |
| Cellective Therapeutics | , | Acquired by MedImmune 2005, Up to $175M |
| Frontida BioPharm | , | Acquired by Adare Pharma Solutions, Dec 2021 |
| BCN Peptides | Barcelona, Spain | Bioactive peptides |
| Nuon Therapeutics | , | Turned into commercial website for weight loss |
| AMT Medical | Ede, Netherlands | Heart Bypass Device |
| CS Bio | Basel, Switzerland | Peptide Synthesizers & Custom Synthesis |
| Isconova | , | Acquired by Novavax, Jun 2013 |
| Medos | , | Merged with Novalung, 2013 became Xenios |
| Neurosave | , | Gone 2018 |
| Geras Bio | , | No info Aug 2021 - May 2023 |
| Caliber Biotherapeutics | , | Website gone more or less, Feb 2016 |
| Finox Biotech | , | Acquired by Gedeon Richter, Jun 2016 |
| Agile Therapeutics | Princeton, NJ | Women's Healthcare |
| XenaCare | , | Gone |
| Styx Biotechnologies | , | No business filings, 2021-2024 |
| Provepharm Life Solutions | Marseille, France | Contract work, Small Molecules and Biologics |
| JPM | Naour, Jordan | Small Molecules & Diagnostic Manufacturing |
| , | Filings late Mar 2025 - Feb 2026 | |
| Rose Research Center | Raleigh, NC | Clinical Research |
| FoRx Therapeutics | Basel, Switzerland | Cancer Compounds |
| Natoli Engineering | Saint Charles, MO | Tablet presses |
| GeneSeek | , | Bought by Neogen |
| Repertoire Immune Medicines | Cambridge, MA | Cell & Peptide-Based Therapies |
| Scendea | Milton, Australia | Product Development & Regulatory Consulting |
| Agno Pharma | Bethlehem, PA | Small molecule CRO, CDMO |
| Agave Biosystems | , | Website gone Nov-Dec 2017 |
| Juno Bio | San Francisco, CA | Vaginal Microbiome Health |
| Hollister-Stier Laboratories | , | Now Jubilant Hollister-Stier |
| DNA Script | Le Kremlin Bicetre, France | Enzymatic DNA Synthesis |
| Knoll Pharmaceutical | , | Taken over by BASF 1975, sold to Abbott 2002, $6.9B |
| Vectalys | , | Merged with FlashCell, May 2018, became Flash Therapeutics |
| Tecomet | Kenosha, WI | Implant Components |
| AQEMIA | Paris, France | AI Drug Discovery |
| Oxygen Biotherapeutics | , | Changed name to Tenax Therapeutics, Sep 2014 |
| Asensus Surgical | Morrisville, NC | Robot surgical system |
| GPCR Therapeutics | Seoul, Korea | Drugs targeting disease-specific GPCR heterodimers |
| MedRACS Clinical Research | , | Website gone Mar 2018 |
| GeneDx | Stamford, CT | Genetic Data |
| Pagari PharmaTech | Garland, TX | Contract Manufacturing - Small Molecules |
| Nextbiotix | , | Renamed Exeliom Biosciences, Jan 2019 |
| Edenbridge Pharmaceuticals | , | Renamed Dexcel Pharma USA, Oct 2024 |
| M6P Therapeutics | St. Louis, MO | Mannose-6-phosphate therapies |
| Igenomix | Dubai, UAE | Contract genetic testing for reproductive health; covid-19 pcr |
| Xcell Biosciences | San Francisco, CA | Cell culturing system |
| VasGene Therapeutics | , | Dissolved Jul 2018 |
| Stago | Marseille, France | Diagnostics |
| Annovis | , | Acquired by Transgenomic, May 2001 |
| Presto Therapeutics | , | Website down Feb 2025 - Jul 2025; Not registered in CA, Feb 2024 - Feb 2025; Spinout from Tempo Bioscience |
| Times Life Science Consulting | , | Website gone Aug 2023 - Dec 2023 |
| Glenmark | Mumbai, India | Generic Small Molecules |
| Pierre Fabre | Avène, France | Oncology, derm / cosmetics |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| SuraMedical | , | Most employees left, not registered in MN |
| Amneal Pharmaceuticals | Ahmedabad, India | Generic Small Molecules |
| Cellucis Biologics | , | Website down Jun 2023 - Dec 2023; Residential Address, Aug 2022 |
| Functional Neuromodulation | , | Shut down Dec 2023; Website under construction Feb 2024 - Mar 2024 |
| OraPharma | , | Owned by Valeant |
| AusperBio | Hangzhou, China | Viral Treatments, ASO |
| , | Website down Jan 2026 - May 2026 | |
| Acumed | Beijing, China | Medical Implants |
| Logical Therapeutics | , | CEO left in 2012, company website shows him as CEO as of Sep 2014. Did not pay clinical trial providers in Apr 2011 or were at least late and nonresponsive |
| Bayer BioPartnering Solutions | Berkeley, CA | Biomanufacturing - recombinant protein and cell therapy modalities |
| Cala Health | San Mateo, CA | Neurological Device |
| Elixir Pharmaceuticals | , | Gone |
| , | Website down Sep 2025 - Dec 2025 | |
| InterMune | , | Bought by Roche, Aug 2014, 8.5B |
| Ei SolutionWorks | , | Seems out of business as of Jan 2019 |
| BTG Specialty Pharmaceuticals | , | Acquired by SERB, Mar 2021 |
| Castle Biosciences | Friendswood, TX | Cancer molecular diagnostics |
| Mojave Therapeutics | , | Gone |
| Brighton Biotech | , | Only employee is an accountant |
| Axios Biosciences | , | Website abandoned, Jan 2017 |
| Aesica Pharmaceuticals | , | Bought by Consort Medical for $374M, Sep 2014 |
| Alturas Analytics | Moscow, ID | Bioanalytical Services |
| EyePoint Pharmaceuticals | Watertown, MA | Miniaturized, sustained-release drug delivery products |
| , | Website down Jan 2026 - May 2026; fka SIRPant Immunotherapeutics | |
| iNeuro Therapeutics | , | Website down Mar 2024 - Jul 2024 |
| Inhibikase Therapeutics | Boston, MA | Therapeutic Vaccines |
| Agenovir | , | Acquired by Vir Biotechnology, May 2018 |
| Yirui Pharma | Hangzhou, China | Small Molecules |
| Ensure Medical | , | Acquired by Cordis, Jul 2006, up to $90M |
| Oryzon Genomics | Cambridge, MA | Biomarker Identification, Drugs |
| Scendea | Amsterdam, Netherlands | Product Development & Regulatory Consulting |
| |
Ljubljana, Slovenia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AusperBio | San Mateo, CA | Viral Treatments, ASO |
| Waypoint Bio | New York, NY | Cell Therapy Production Design |
| Confluent Medical Technologies | Warwick, RI | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Cell Guidance Systems | Cambridge, UK | Life science research tools |
| Bristol Myers Squibb | Pennington, NJ | Biologics Process Development |
| R-Pharm | Moscow, Russia | Medical Equipment |
| Fresh Wind Biotechnologies | , | Founders and employees all gone, Nov 2024 |
| Base Pair Biotechnologies | Pearland, TX | Aptamers and related Services |
| Chembio Diagnostic Systems | Medford, NY | Rapid diagnostics |
| Claros Diagnostics | , | Acquired by Opko Health, Oct 2011 |
| Senn Chemicals | Dielsdorf, Switzerland | Contract Mfg - peptides, amino acid derivatives, carbohydrates, small molecules, etc. |
| Celgene | , | Bought by BMS, Nov 2019, $74B |
| Algenix | , | MN Business revoked, Mar 2004 |
| BioIntegral Surgical | , | Don't seem to have any employees, Feb 2025 |
| Dr. Reddy's Laboratories | Qutubullapur, India | Small Molecules, Custom Pharma Services |
| Eloxx Pharmaceuticals | Nes Tziona, Israel | Rare Genetic Diseases |
| Microsulis Medical | , | Acquired by AngioDynamics, 2013 |
| Ferrokin Biosciences | , | Bought by Sandoz Jul 2012, $1.525B |
| Fast Biomedical | , | Website down Feb 2024 - Jul 2024 |
| TransGenex Nanobiotech | Tampa, FL | Nanoscale technologies |
| EmboMedics | , | Not registered in MN, all employees gone Aug 2022 |
| LenioBio | Düsseldorf, Germany | Cell-free protein expression kit |
| Torpedo Bio | , | |
| Siegfried | Pennsville, NJ | Contract Drug Manufacturing, APIS, Development |
| StemPar Sciences | , | Website disappeared, no news |
| Remedy Pharmaceuticals | , | Product Acquired by Biogen, May 2017 |
| CancerVax (2) | , | Shut down Nov 2024; LI gone Nov 2023 |
| Lusochimica | , | Owned by Menarini |
| Pluristem Therapeutics | , | Renamed Pluri, Jul 2022 |
| Pierre Fabre | Cahors, France | Oncology, derm / cosmetics |
| Ostrea Bio | , | Founded 2017, No info, President gone Mar 2019 |
| HiTech Health | Ballynahown, Ireland | Biopharm CDMO |
| Paidion Research | , | Acquired by Premier Research, May 2021 |
| Debiopharm | Lausanne, Switzerland | Contract Development & Manufacturing |
| True North Therapeutics | , | Acquired by Bioverativ, Jun 2017, $400M + $425M milestones; Spinout from iPerian, 2013 |
| Snoozeal | , | Renamed Signifier Medical Technologies |
| Link Technologies | , | Acquired by LGC, Jul 2017 |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Cogent Biosciences | Waltham, MA | Cellular immunotherapies |
| Smart Pharma Consulting | Hoofddorp, Netherlands | Pharma Consulting |
| Eureka Genomics | , | Acquired by Affymetrix, May 2015, $14M |
| Therapure Biopharma | , | Acquired by Resilience, Apr 2021 |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Aldexa Therapeutics | , | Changed name to Aldeyra Therapeutics, Mar 2014 |
| Daiichi Sankyo | Basking Ridge, NJ | Small Molecules, Biologics |
| Gener8 | Carlsbad, CA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Tiefenbacher | Hamburg, Germany | Contract Small Molecules & Devices |
| Covidien | , | Bought by Medtronic, Jan 2015, $42.9B |
| Orcas Therapeutics | , | Renamed Hygeia Therapeutics, Dec 2007 |
| AbbVie | Shanghai, China | Small Molecules, Biologics |
| PrimCells | , | Website gone, Mar 2019; Never a registered CA business |
| Cyterix Pharmaceuticals | , | Closed 2013 |
| Wesana Health | , | Website down Jun 2023 - Dec 2023 |
| Ajinomoto Bio-Pharma Services | Visakhapatnam, India | Contract Manufacturing |
| Prothya Biosolutions | Amsterdam, Netherlands | Services and plasma-derived medicinal products |
| Aethlon Medical | San Diego, CA | Dialysis Filtration |
| CoMind | London, UK | Non-invasive brain monitoring system |
| Immunodiagnostic Systems | Frankfurt, Germany | Immunoassay System |
| Lake Region Medical | , | Bought by Greatbatch, Oct 2015, $1.73B |
| PCI Pharma Services | Bridgend, UK | Contract Manufacturing, Services |
| Ocular Systems | , | Merged with SightLife Surgical, Apr 2014 |
| MeDiNova Research | , | Now part of Accelacare |
| Claris Lifesciences | , | Bought by Baxter, Jul 2017 |
| G7 Therapeutics | , | Acquired by Heptares, Nov 2016, $12M |
| Novelion Therapeutics | , | Liquidated Jan 2020 |
| Histide | Montpellier, France | Cell Recoding Molecules |
| Offspring Biosciences | Södertälje, Sweden | Cell & Tissue Imaging |
| Accellacare | Winston-Salem, NC | Clinical Research |
| AstraZeneca | Boston, MA | Biologics |
| ALCOR Scientific | Smithfield, RI | Clinical Lab |
| Capellon Pharmaceuticals | , | Website down Nov 2018; Website looks like it's from 2002 |
| Ausun Pharm | Taizhou, China | APIs, CDMO |
| XStalBio | , | Folded |
| Allcyte | , | Acquired by Exscientia, Jun 2021 |
| A2M Pharma | , | Website down Jan 2021 - May 2021 |
| Respironics | , | Bought by Philips, Mar 2008, $5.1B |
| EpiFinder | , | Gone May 2025 |
| , | Website down Jun 2025 - Dec 2025 | |
| Control X-Medical | Dunakeszi, Hungary | Medical X-Ray Systems |
| Reserva | , | Renamed NeurMedix, 2016 |
| ONLINE Engineering | Manistique, MI | Cell Culture Media Production Equipment |
| Somna Therapeutics | , | Acquired by Restech, Jun 2020 |
| Atara Biotherapeutics | Thousand Oaks, CA | Peptibody, Monoclonal Antibody, Cell Therapy |
| , | Gone Mar 2024 | |
| TE Connectivity | Plymouth, MN | Contract Medical Devices |
| Orchid Orthopedic Solutions | Mason, MI | Contract Medical Device Work |
| Gradian Diagnostics | , | Website down Feb 2025 - Mar 2025; Linkedin Gone Jun 2025 |
| SEQENS | Pune, India | Analytical method validation, API development |
| InnoVec Biotherapeutics | Beijing, China | AAV-Based Gene Therapy |
| MiRXES | Singapore, Singapore | MiRNA research technologies |
| Vironova | , | Website down Feb 2024 - Dec 2024 |
| Anterios Therapeutics | , | Acquired by Allergan, Jan 2016, $90M |
| MiRus | Marietta, GA | Spine Implants |
| Nuage Therapeutics | Barcelona, Spain | Small molecule modulators targeting intrinsically disordered proteins and biomolecular condensates |
| Polpharma Biologics | Gdańsk, Poland | Biosimilars |
| Syntrix Biosystems | , | Renamed Syntrix Pharmaceuticals |
| GMP-Orphan France | , | Renamed Orphalan |
| Forte Bio | , | Folded into Sartorious after purchasing from Danaher, Oct 2019 |
| , | Acquired by XenoTherapeutics, Oct 2025 (nonprofit) | |
| Sensible Biotechnologies | Bratislava, Slovakia | Engineering Cells for RNA production |
| Clinnex | Ahmedabad, India | Clinical Research |
| InVasc Therapeutics | , | Shut down 2012 |
| Hygeia Therapeutics | , | Gone, pre-Jun 2016 |
| Trenzyme | Konstanz, Germany | Highly customized services in cell line development and recombinant protein production |
| Aixial Group | Greensboro, NC | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Milo Biotechnology | , | Academic startup, no real progress from 2016-2022 |
| Hologic | Macquarie Park, Australia | Diagnostic, Imaging |
| Woomera Therapeutics | , | Website from 2013 as of Dec 2020 |
| Wockhardt | Daman, India | Generics, Contract Manufacturing |
| Paradigm4 | Waltham, MA | Cellular Analysis Software |
| FMI Medical Systems | , | Website down Sep 2024 - Feb 2025 |
| Epitype | Jena, Germany | Molecular cancer diagnostics |
| Espero Pharmaceuticals | , | Renamed Espero Biopharma |
| Three Rivers Pharmaceuticals | , | Now Kadmon |
| Adeona Pharmaceuticals | , | Renamed Synthetic Biologics, Dec 2011 |
| Eragen Biosciences | , | Bought by Luminex 2011 |
| Kolon Life Science | Seoul, Korea | Cell & Gene Therapy, APIs |
| Wheaton | , | Renamed DWK Life Sciences |
| VxP Biologics | Indianapolis, IN | Biologics Contract Work |
| Urovant Sciences | , | Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Bluestar Genomics | , | Renamed ClearNote Health |
| Farbridge Pharma Consulting | San Diego, CA | Pharmaceutical Consulting |
| ConvaTec | London, UK | Wound Care, Infusion Systems, Critical Care |
| ConjuChem | , | Bankrupt 2011 |
| Cytotools | , | Renamed BioXXmed, stopped doing R&D |
| Armour Therapeutics | , | Seems inactive, no employees on LI |
| Entact Bio | Watertown, MA | Bifunctional molecules that recruit deubiquitinating enzymes to target proteins to remove ubiquitin |
| Aizon | San Francisco, CA | AI for Pharma Manufacturing |
| |
Singapore, Singapore | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| tBrexa | , | Website down Jul 2023 - Dec 2023 |
| Medpace | Cincinnati, OH | Clinical Research |
| Asubio | , | Merged into Daiichi Sankyo, closing down Feb 2017 |
| Zenshine Pharmaceuticals | Nanjing, China | Small Molecules |
| Igenomix | Jersey City, NJ | Contract genetic testing for reproductive health; covid-19 pcr |
| NanoTemper Technologies | Munich, Germany | Protein Screening Technology |
| PL Developments | , | Parts of website taken over |
| St. Teresa Medical | , | Winding down May 2024; LI page gone Nov 2023 |
| Nkarta Therapeutics | South SF, CA | Allogeneic cellular immunotherapy platform |
| TRIFARMA | Ceriano Laghetto, Italy | APIs |
| AngioGenetics | , | Bankrupt, Jun 2011 |
| Allucent | Saint-Laurent, QC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Affinia Therapeutics | Waltham, MA | Gene Delivery |
| Venclose | , | Acquired by BD, Dec 2021 |
| Patheon | Cincinnati, OH | Contract Manufacturing and Development |
| OPK Biotech | , | Bankrupt/Folded, Apr 2014 |
| Pathnostics | Irvine, CA | Diagnostics |
| Lovelace Scientific | Albuquerque, NM | Tox, Analytical, Formulation, PK, Pharmacology |
| Bakx Therapeutics | , | Shut down Jul 2023 |
| EUSA Pharma | , | Acquired by Recordati, Dec 2021, $850M; Spun out of Jazz, Mar 2015; Acquired by Jazz Pharmaceuticals, Apr 2012, $700M |
| Conexio Genomics | , | Acquired by Illumina, Jan 2016 |
| ValanBio Therapeutics | Durham, | Small Molecule Antibiotic for UTI |
| KnuEdge | , | Website Expired, Aug-Oct 2018 |
| Acrivon Therapeutics | Watertown, MA | Checkpoint Inhibitor |
| BAG Health Care | Lich, Germany | Aseptic Filling & Lyophilization |
| Arana Therapeutics | , | Acquired by Cephalon, Aug 2009 |
| Dispendix | Stuttgart, Germany | Automation and Microfluidics for Genomics and Drug Discovery |
| Quotient | , | Renamed AliveDx, Jul 2023 |
| Replimune | Abingdon, UK | Oncolytic immunotherapy |
| Oxis International | , | Renamed GT Biopharma |
| Becton Dickinson | Franklin Lakes, NJ | Various medical devices and health products |
| Zetta Genomics | Cambridge, UK | Genomic Data Management |
| Qubit Pharmaceuticals | Paris, France | Binding Energy Quantification Platform |
| Northern Biologics | , | All products acquired as of Nov 2020 |
| Atossa Genetics | , | Renamed Atossa Therapeutics, Jan 2020 |
| Liponex | , | Acquired by ImaSight in reverse merger, Jun 2008 |
| Novonesis | Bagsvaerd, Denmark | Enzymes |
| Fortimedix Surgical | , | Acquired by Medtronic, Nov 2024 |
| Bio-Nucleonics | , | Website down May 2021 - Feb 2022; Consistently deliqnuent on business filings |
| Hygia Health Services | , | Acquired by Stryker, May 2018 |
| London Genetics | , | Website Gone 2-19-14, 10-14-14 |
| Ista Pharmaceuticals | , | Bought by Bausch & Lomb - 2012 |
| Birdie Biotech | , | No website Dec 2019 - Dec 2020 |
| Custopharm | , | Acquired by Hikma, Apr 2022, $375M + $50M milestones |
| TE Connectivity | San Rafael, Costa Rica | Catheter manufacturing & development |
| Enable Life Sciences | Cambridge, MA | Pharma Consulting |
| BioSpectra | Bangor, PA | GMP-grade ingredients and reagents |
| MicroVention | , | Now Terumo Neuro |
| CardioGenics | , | May technically exist, seem inactive Nov 2020 |
| Maxygen (1) | , | Dissolved, Aug 2013, Final liquidation payout Jul 2014 |
| IamFluidics | Enschede, Netherlands | Microparticles |
| Kalon Biotherapeutics | , | Acquired by Fujifilm Diosynth Dec 2014 |
| Oxitope | , | Shut Down Feb 2019 |
| Ascendis Pharma | Hellerup, Denmark | Prodrug therapies |
| BresaGen Inc | , | Merged with Novocell & CyThera to become ViaCyte in 2004 |
| RQM+ | Cary, NC | Regulatory compliance consulting |
| Bio-techne | Devens, MA | In-vitro diagnostics devices |
| greenovation Biotech | , | Renamed Eleva, May 2020 |
| ImmusanT | , | Website down Aug 2020 - Dec 2020; No business filings 2018-2020 |
| Manchester Pharmaceuticals | , | Acquired by Retrophin, Mar 2014, $29.5M + $33M milestones |
| Biorelate | Manchester, UK | AI Data Curation |
| Cytera CellWorks | , | Renamed Mytos |
| Second Source Medical | , | Acquired by Medeologix, Nov 2022 |
| Fujirebio Diagnostics | Malvern, PA | Biomarkers |
| AREVA Med | , | Renamed Oranomed, Jan 2018 |
| Proven Process | , | Acquired by NextPhase Medical Devices, May 2021 |
| , | Website down Jun 2025 - Dec 2025 | |
| ReShape Medical | , | Acquired by EnteroMedics, Oct 2017 |
| QC Ware | Paris, France | Molecular Discovery Platform |
| Skylit Medical | , | Renamed Clarify medical |
| Ventec Life Systems | Bothell, WA | Portable ventilator, multi-purpose device |
| Cellarcus Biosciences | La Jolla, CA | Extracellular Vesicle Analysis Assays |
| ANP Technologies | Newark, DE | Immunogenicity Testing, Biotech Reagents, Contract Work |
| Cogentix Medical | , | Acquired by Laborie, Apr 2018 |
| Global BioTherapeutics | , | Business not registered in CA, LinkedIn says owner is in Mexico, emails bouncing Oct 2019 |
| Synedgen | Claremont, CA | Biofilm Control |
| BioAegis Therapeutics | North Brunswick, NJ | Protein replacement therapies |
| Ivera Medical | , | Bought by 3M, Feb 2015 |
| Ysopia Bioscience | , | Website gone Jan 2024 - Dec 2024 |
| Blade Therapeutics | , | Shut down Dec 2022 |
| Moon Surgical | Paris, France | Robotic Surgery System |
| Stallergenes Greer | Lenoir, NC | Allergen Desensitization |
| Vernacare | Maple, ON | Surgical Devices |
| Senda Biosciences | , | Merged with Laronde, Oct 2023 to become Sail Biosciences |
| CERAMIDE THERAPEUTICS | , | No info. Jun 2015. $1.5M SBIR grant 2011 |
| PureTech Health | Boston, MA | Brain, Immune, Gut axis |
| BHV Pharma | , | Acquired by Avolynt, Mar 2016 |
| Central Pharma | Bedford, UK | Filling, Packaging |
| Context Therapeutics | Philadelphia, PA | Treatments for hormone-driven cancers |
| BellBrook Labs | Madison, WI | High-Throughput Screening Assays |
| Life Couriers | Munich, Germany | Diagnostics |
| Veristat | Southborough, MA | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Olio Labs | San francisco, CA | Software to de-risk clinical trials |
| Encorium | , | Bankrupt |
| Misfolding Diagnostics | , | Renamed Protego Biopharma, Dec 2021 |
| Kolltan Pharmaceuticals | , | Bought by Celldex, Nov 2016, $62.5M + $172.5M milestones |
| Everis Medical | Memphis, TN | Surgical Devices, Compartment Pressure Monitor |
| Cellumen | , | Acquired by Apredica, Aug 2010, £2.7M |
| Reistone Biopharma | , | Website down Jun 2024 - Nov 2024 |
| Velos | , | Acquired by WCG, Mar 2018 |
| Trivitron Healthcare | Chennai, India | Medical Devices |
| Lonza | Portsmouth, NH | Contract Manufacturing, Reagents, Stem Cells, Services |
| Poxel | Lyon, France | Drugs for metabolic disease |
| Apotex | Toronto, ON | Small Molecule Generics |
| Virtuoso Therapeutics | Shanghai, China | Therapeutic Antibodies |
| IntelliSyn R&D | , | Acquired by X-Chem, Jan 2021 |
| Greenpeptide | , | Renamed BrightPath Biotherapeutics, Jul 2017 |
| Alize Pharma | , | Acquired by Millendo Therapeutics, Dec 2017 |
| Heraeus Medical | Diadema, Brazil | Medical Devices |
| Neuromatters | , | Shut down Dec 2019 |
| Angelini Pharma | Ancona, Italy | Disinfectants, Reformulated Small Molecules |
| , | Website down Sep 2025 - Feb 2026 | |
| Abpro | Lexington, MA | Antibodies |
| Nalpropion Pharmaceuticals | , | Bought by Currax, Sep 2019 |
| EpiVax Oncology | , | Website down Dec 2020 - May 2021; Spinout of EpiVax |
| AptaIT | , | Website gone and for sale Nov 2019 |
| , | Website down Dec 2025 - Apr 2026 | |
| , | No news 2017 - Apr 2026 | |
| Bioeq IP | Zug, Switzerland | Biosimilars |
| DFS Pharma | , | Acquired by Medrio, Apr 2021?; fka DataFlex Solutions |
| Cymbiotics | , | Gone 2019-2020 |
| AAX Biotech | Solna, Sweden | Next-gen Antibody Therapeutics |
| Procyon Pharmaceuticals | , | Now Nexcyon Pharmaceuticals |
| Tequesta BioScience | , | Defunct |
| WaferGen Biosystems | , | Acquired by Takara Bio, Mar 2017, $50M |
| Hoechst Marion Roussel | , | Merged with Rhône-Poulenc 1999, merged with Sanofi 2004 |
| Sequella | , | Ancient website ©2017, last news 2017 |
| Viant Medical | Orchard Park, NY | Contract Medical Devices |
| Recipharm | Leganés, Spain | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| arcoris bio | Schlieren, Switzerland | Multiplex imaging of nucleic acids and proteins |
| Transave | , | Merged with Insmed Dec 2010 |
| Innolign Biomedical | , | Shut Down Feb 2021 |
| Pionyr Immunotherapeutics | , | Acquired by Akena Oncology, Aug 2023; fka Precision Immune |
| Neurotec Pharma | , | Website gone May 2020; No news since 2014 |
| Nanotein | Berkeley, CA | Next-gen CAR-T Cell Activation & Expansion |
| Forum Pharmaceuticals | , | Closed Jun 2016 after failed trial |
| Parexel | Harrow, UK | Clinical Research |
| Harrisvaccines | , | Bought by Merck Animal Health, Nov 2015 |
| Antares Therapeutics | South SF, CA | Small Molecule Technologies |
| Bio-Works | Uppsala, Sweden | Purification technologies |
| Elegen | San Carlos, CA | DNA writing |
| Snowdon Pharmaceuticals | , | Does not appear active, Apr 2019 |
| Avaxia Biologics | , | IP acquired by Circle33 |
| PharmaLegacy | Shanghai, China | Preclinical Pharmacology |
| Immundiagnostik | Bensheim, Germany | Antibodies, Antigens, Kits, etc. |
| Amneal Pharmaceuticals | Vizag, India | Generic Small Molecules |
| MindChild Medical | North Andover, MA | Fetal Monitoring System |
| Infant Bacterial Therapeutics | Stockholm, Sweden | Premature Infant Treatments |
| Rigel Pharmaceuticals | South SF, CA | Small Molecules |
| Esco Aster | Singapore, Singapore | Biologics CDMO |
| Harbor Therapeutics | , | Acquired by Crede Capital Group, Jan 2015. Website gone. |
| Pressure Biosciences | , | Merged with Cannaworx, SkinScience Labs and pivoted to weed products, May 2020 |
| TopoTarget USA | , | Sold to Apricus Bio, Dec 2011 |
| Cytophenix | Perth, Australia | Sepsis Diagnosis |
| Acino | Liesberg, Switzerland | Novel drug delivery formulations |
| Blue Sky Bioservices | , | Acquired by LakePharm Mar 2016 |
| Echo Therapeutics | , | Website down Jun 2018; Company slashed workforce and seems to be run by a lawyer and an accountant Jan 2018 |
| , | Renamed CelLBxHealth, Oct 2025 | |
| Angioslide | , | Gone, Oct 2009 |
| Nanoptima | Cheshire, UK | Controlled-release drug depots |
| Progenics Pharmaceuticals | , | Acquired by Lantheus, Jun 2020 |
| G & H ITL | Rochester, NY | CDMO providing end-to-end design and manufacturing services for medical devices, in-vitro diagnostics, and laboratory instruments |
| Enzyme by Design | Chicago, IL | Enzymes for Cancer Therapy |
| Novare Bio-Logistics | , | Website Gone, Jan 2019 |
| Dynavax Technologies | Emeryville, CA | Synthetic oligonucleotides vaccines, adjuvants |
| Genesis BPS | Ramsey, NJ | Blood Handling |
| Antigenics LLC | , | Now Agenus |
| Ollin Biosciences | Austin, TX | Bispecific Antibodies |
| Hyrax Biosciences | Cape Town, South Africa | DNA Sequence Analysis |
| Amneal Pharmaceuticals | Piscataway, NJ | Generic Small Molecules |
| AbbVie | Sligo, Ireland | Contract Manufacturing |
| Regenerex | , | Renamed Talaris Therapeutics, Apr 2019 |
| Sphere Bio | Cambridge, UK | Novel single cell analysis systems |
| Scandinavian Biopharma Holding | Solna, Sweden | Various vaccines |
| Myotec Therapeutics | , | Merged with Hybrid Biosystems to become PsiOxus Therapeutics, Dec 2010 |
| TranscripTx | , | Merged with ReCode Therapeutics, Mar 2020 |
| Mabpharm (2) | Shanghai, China | Biosimilars |
| Arvinas | New Haven, CT | Bifunctional small molecules for protein degradation |
| Praxis Pharmaceutical | , | Possibly rolled into Praxis Precision Medicines |
| Anagnostics | , | Assets acquired by CubeDx, Jul 2015 |
| Axcynsis Therapeutics | Shanghai , China | Antibody-X Conjugates |
| Surflay Nanotec | Berlin, Germany | Protein Interaction Monitoring, Contract Research |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Lambda Therapeutic Research | Ahmedabad, India | Clinical Research |
| Amstem | , | SEC problems |
| ABgene | , | Bought by Apogent, Dec 2001 |
| MeiraGTx | London, UK | Gene Therapy |
| Pulse Technologies | Quakertown, PA | Contract Medical Device Manufacturing |
| Phoenix Tissue Repair | , | Folded into BridgeBio, Sep 2023 |
| Diaprost | , | No news 2015 - 2025, CEO has more important job |
| XVIVO | Mölndal, Sweden | Transplantation Systems |
| Hippocampus Pharma | , | Renamed HCS Pharma |
| Aclaris Therapeutics | St. Louis, MO | Novel topical dermatological therapies |
| Carrera Bioscience | , | Website down/taken over Oct 2021 - Dec 2021 |
| Emerald Therapeutics | , | Seem to have pivoted to a lab service provider called Emerald Cloud Lab |
| Telix Pharmaceuticals | Sacramento, CA | Radio immunotherapy |
| PQE Group | Reggello, Italy | Medical Device Consulting |
| CLOVERNA | Okayama, Japan | RNA Targeting Oligonucleotides |
| Boston Therapeutics | , | Reverse merged with Nanomix Nov 2021; fka Avanyx Therapeutics |
| Rigvir | Riga, Latvia | Oncolytic Virotherapy |
| Agalimmune | , | Acquired by BioLineRx, Mar 2017, $6M |
| HiTech Health | Dublin, Ireland | Biopharm CDMO |
| Atonarp | Tokyo, Japan | Molecular Analysis by Mass Spec |
| King Pharmaceuticals | , | Bought by Pfizer, Oct 2010, $3.6B |
| Onkaido Therapeutics | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Chai Discovery | San Francisco, CA | AI Antibody Discovery |
| Ocumension Therapeutics | Shanghai, China | Ophthalmic Pharmaceuticals |
| Soley Therapeutics | South SF, CA | Proprietary imaging, AI, and automation that allow us to translate whole cell information |
| Duramed | , | Acquired by Barr Labs 2001 |
| Avalign Technologies | Rosemont, IL | Orthopedics & Surgical |
| Rotation Medical | , | Bought by Smith & Nephew, Oct 2017 |
| Sanguine Technologies | , | Renamed Veravas, Nov 2018 |
| Siegfried | Minden, Germany | Contract Drug Manufacturing, APIS, Development |
| Recovery Pharmaceuticals | , | Business license revoked Mar 2008 |
| Targeted Genetics | , | Changed name to AmpliPhi Biosciences |
| Thermo Fisher | Ogden, UT | Molecular Biology Supplies |
| Freedom Meditech | , | Acquired by Trividia Health, Jan 2017 |
| Arrayon Biotechnology | , | Acquired by Endetec@Veolia, 2011 |
| Locate Bio | Nottingham, UK | Gene, Cell Therapy |
| Cipla USA | Warren, NJ | Generics, APIs, Formulation |
| Tollys | , | Website down Sep 2023 - Mar 2024 |
| Celsis IVT | , | Merged with Bioreclamation and became BioreclamationIVT |
| Ainostics | Manchester, UK | AI Dementia Diagnostics |
| United Immunoassay | , | Business revoked Jan 2022 |
| DNALite Therapeutics | , | Renamed Particella |
| Gambro | , | Acquired by Baxter, Sep 2013 |
| AIROS Medical | Audubon, PA | Compression Therapy Devices |
| Embody | Norfolk, VA | Soft Tissue Healing |
| GTX Medical | , | Renamed ONWARD |
| Vyriad | Rochester, MN | Immunovirotherapy |
| AOP Orphan Diseases | Vilnius, Lithuania | Orphan disease treatments |
| Metactive Medical | , | Renamed Artio Medical, but company seems to have just disappeared Dec 209 |
| UCB Pharma | Bulle, Switzerland | Small Molecules, Biologics |
| Bachem | Torrance, CA | Contract Peptides, Oligos |
| ChromoTek | , | Acquired by Proteintech, Oct 2020 |
| Pfizer | Karlsruhe, Germany | Small Molecules, Biologics, Vaccines |
| OxOnc Development | , | Website gone Apr 2018 |
| , | Website down Apr 2026, seems bankrupt | |
| VBL Therapeutics | , | Merged with Notable Labs, Oct 2023 |
| Ferring Pharmaceuticals | Jesenice, Czech Republic | Manufacturing |
| Luye Pharma | Shanghai, China | Small Molecules |
| BlueRock Therapeutics | Toronto, ON | Stem Cell Therapies |
| BioDatomics | , | Website gone Jan 2019 |
| Saol Therapeutics | Roswell, GA | Small Molecules |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| QuA Vodis | , | Gone |
| Nutriband | Orlando, FL | Small Molecules, 505(b)(2) |
| Woocheon Pharma | , | Merged with Hana Pharm, 1996 |
| Oncomethylome Sciences | , | Renamed MdXHealth, Sep 2010 |
| AmpliPhi Biosciences | , | Merged with C3J Therapeutics, May 2019 to become Armata Pharmaceuticals |
| 4-Antibody | , | Bought by Agenus, Jan 2014, $10M |
| LatchBio | San Francisco, CA | Cloud bioinformatics platform to help biological teams accelerate their R&D. |
| Chemveda Life Sciences | Hyderabad, India | Drug Discovery & development Services |
| Gemini Laboratories | , | Acquired by Amneal, May 2018 |
| Eversana | Chicago, IL | Commercialization Consulting |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| Axela | , | Acquired by Angle plc, Oct 2017, $6M |
| argenx | Zwijnaarde, Belgium | Antibody therapies |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Sanner | Bensheim, Germany | Medical Device CDMO |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing Platform |
| Facet Biotech | , | Bought by Abbott 2010 |
| Able Medical Devices | Gwinn, MI | Implant, Device Production |
| Amniotics | , | Renamed Magle Biopharma, Jan 2025 |
| Global Pharmaceuticals | , | Merged with Impax Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Savant HWP | , | Gone 2019 |
| RMI Pharmacokinetics | , | Filings late May 2024 - Aug 2025 |
| Circadiance | Export, PA | CPAP Mask |
| Flosonics | Sudbury, ON | Wireless wearable hemodynamic monitoring device using non-invasive ultrasound |
| iuvo BioScience | Rochester, NY | Ophthalmic Clinical Research Services |
| Novare Pharmaceuticals | , | Funding cut off Apr 2017 |
| Numerate | , | Website down Sep 2020 - Mar 2021 |
| TATUM Bioscience | Sherbrooke, QC | Multimodal Nanofilaments |
| AbCheck | , | Acquired by Ampersand Biosciences, Jan 2024 |
| Trutino Biosciences | San Diego, CA | Locally activated cytokine precursors |
| Applied Biomics | Hayward, CA | Proteomics services & products |
| Innvocept Global Solutions | Mumbai, India | Analytical Instruments |
| Aliri | Loos, France | Contract Mass Spec |
| Hovione | Ringaskiddy, Ireland | Contract Manufacturing |
| Varda | El Segundo, CA | Processing pharmaceuticals in space |
| Quentis Therapeutics | , | Shut down late 2020 |
| Perlegen | , | No Site |
| Dornier MedTech | Moscow, Russia | Urology Devices |
| Eyegate Pharma | , | Renamed Kiora Pharmaceuticals, Nov 2021 |
| Lion TCR | Singapore, Singapore | T cell therapy |
| Alphina Therapeutics | New Haven, CT | NAMPT Inhibitor for solid tumors |
| Quanta Dialysis Technologies | Warwick, UK | Dialysis Technology |
| Bio-Technical Resources | Manitowoc, WI | Biotech Assays, Development |
| Develco Pharma | Birsfelden, Switzerland | Generics |
| Midatech | , | Became Biodexa Pharmaceuticals, Dec 2022 |
| Agena Bioscience | Shanghai, China | High throughput targeted & multiplexed genetic analysis |
| , | Website down Jul 2025 - Dec 2025 | |
| Partners in Biopharma Consulting | , | Website dated 2011 and looks circa 2002 |
| Vifor Pharma | , | Acquired by CSL, Aug 2022, $11.7B |
| , | CEO listed on Website Oct 2025 left Aug 2022 | |
| Be Cool Pharmaceutics | , | Website down Aug 2024 - Sep 2024; Professor side gig |
| Small Pharma | , | Acquired by Cybin, Aug 2023 |
| Axcan Pharmaceuticals | , | Renamed Aptalis after acquiring Eurand, May 2011 |
| MY01 | Montréal, QC | Sensor for Acute Compartment Syndrome |
| Avantogen Oncology | , | Withdrawn Sep 2020 |
| Optys Tech | , | No news 2016 - Oct 2024, No linkedin |
| VL34 | , | Renamed Ohana Biosciences, Feb 2017 |
| Pacific Biomarkers | , | Renamed Nexelis, Sep 2019 |
| EastHORN Clinical Services | , | Acquired by Novotech, Jan 2023 |
| Animas | , | Shut down, Oct 2017 |
| , | Acquired by Boston Scientific, Apr 2025, $664M | |
| Osteolab | , | Spam site |
| GlycoVaxyn | , | Acquired by GSK, Feb 2015, $190M |
| Recipharm | Bangalore , India | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Pfizer | Ascoli Piceno, Italy | Small Molecules, Biologics, Vaccines |
| Pharmaceutical Advisors LLC | , | No website update since 2005 as of Apr 2019 |
| Nucleics | Woollahra, Australia | DNA Sequencing Software |
| |
Kaiseraugst, Switzerland | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Hap10 Bio | , | Website down Feb 2024, never registered business |
| Rare Thyroid Therapeutics | , | Acquired by PledPharma, Oct 2020 |
| Medtronic | Brooklyn Center, MN | Medical Devices |
| VHsquared | , | Website states closed down; Website down Apr 2023 - Jun 2023 |
| Gentian USA | Moss, Norway | IVD Products |
| Asinex | Amsterdam, Netherlands | Small Molecule Library Creation |
| Genactis | Hemel Hempstead, UK | Pharmaceutical Consulting |
| 4G Clinical | Wellesley, MA | Clinical Trial Software |
| ProNAi Therapeutics | , | Renamed Sierra Oncology, Jan 2017 |
| AccuDx | , | no updates since 2012 as of Jan 2019. Seems not so serious |
| Santen | Osaka, Japan | Ophthalmics |
| Avive Solutions | Brisbane, CA | Automated External Defibrillator |
| Sterling Industries | Barrie, ON | Medical Device Contract Manufacturing & Development |
| MetaboMed | , | Assets sold Jan 2024; Website down Mar 2023 - Sep 2023 |
| Cephea Valve Technologies | , | Acquired by Abbott, Jan 2019 |
| Aryx Therapeutics | , | Terminated all employees in 2010, shell company |
| WaVe Life Sciences | Lexington, MA | Stereopure oligonucleotides |
| Procarta Biosystems | , | Liquidating Aug 2021 |
| Omicia | , | Renamed Fabric Genomics, Mar 2017 |
| Novian Health | Chicago, IL | Device for breast tumor ablation |
| Photoswitch Biosciences | , | Website Down May 2024 - Dec 2024 |
| Global BioDevelopment | , | Website gone |
| |
Wuxi, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Congen Biotechnologie | Berlin, Germany | PCR Products |
| Surgisense | , | Presumed gone |
| Rosetta Genomics | , | Filed for Chapter 7 bankruptcy, Jun 2018 |
| H-Cyte | , | Business not registered Apr 2024 - Oct 2024; Website under construction Feb 2023 - Oct 2024; fka MEDOVEX |
| MolecularMD | , | Acquired by ICON plc, Feb 2019 |
| CharlestonPharma | , | No company news Sep 2020 - Dec 2023, CEO quit Dec 2021, still on website Dec 2023 |
| LYO-X | Basel, Switzerland | Consulting and PK/PD Modelling Services for Preclinical and Clinical Biotherapeutics Development |
| AAPharmaSyn | Ann Arbor, MI | Contract Chemistry |
| Jarvik Heart | New York, NY | Valveless Ventricular Assist Device |
| SIWA Therapeutics | Chicago, IL | Monoclonal Antibodies Targeting Senescent Cells |
| CentryMed Pharmaceutical | , | Website down Feb 2025 - Jul 2025 |
| Bionsight | Chuncheon, Korea | Database For Research |
| Thermo Fisher | Grand Island, NY | Cell Culture Manufacturing |
| Archemix | , | Liquidating, Hemophilia assets bought by Baxter |
| Viatris (1) | , | Acquired by Meda, Aug 2005, €750M |
| Taxus Cardium | , | Renamed Gene Biotherapeutics, became royalty company |
| LTZ Therapeutics | Redwood City, CA | Immunotherapies |
| Collaborations Pharmaceuticals | Raleigh, NC | Rare Disease Treatments |
| Adaptherapy | , | Website gone Jun 2023 - Sep 2023 |
| Digilab | , | Licensed IP to Cellular Life Sciences |
| Siemens Healthineers | Forchheim, Germany | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Panaxia | Lod, Israel | Medical Cannabis |
| Clarient | , | Acquired from GE Healthcare by NeoGenomics, Oct 2015, $265M |
| Apicore | East Windsor, NJ | API Development & Manufacturing |
| VIDA Diagnostics | Edina, MN | Lung Diagnostic Technology |
| Vilya | Seattle, WA | Computation Biology Drug Discovery |
| Advanced Peptides | , | No business filings since 2011 |
| IROA Technologies | Nellysford, VA | Metabolic Analysis Products |
| SmartNuclide Biopharma | Shanghai, China | Radiopharmaceuticals |
| Precision Biomarker Resources | , | Website down May 2021 - Sep 2021 |
| BCR Corporation | , | Website gone Apr 2019, Seems defunct |
| Kumquat Biosciences | San Diego , CA | Cancer Therapies |
| Cardiox | , | Employees all seem gone, Oct 2023 |
| Celldex Therapeutics | Needham, MA | Small Molecules, Biologics, Vaccines |
| Nautilus Biotechnology | Seattle, WA | High-throughput, low-cost platform for analyzing and quantifying the human proteome |
| Cranial Technologies | Tempe, AZ | Flat Head Treatment Device |
| Altiva | , | Acquired by Exactech, Jan 2008 |
| BioCrea | , | Website Gone, Feb 2018 |
| Perbio Science | , | Acquired by Fisher Scientific, Jun 2003 |
| Atom Bioworks | Cary, NC | DNA-based Drug Design |
| Exogenesis | , | Website down Feb 2024 - Oct 2024 |
| Certara | Berlin, Germany | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Eli Lilly | San José, Mexico | Small Molecules, Biologics |
| ChemGenex | , | Bought by Cephalon Mar 2011 |
| Aurigon Life Science | München, Germany | Toxicology, pharmacology, testing |
| Boston Mountain Biotech | , | Gone Oct 2020 |
| Novick Biosciences | , | Website taken over, Jun 2025 |
| Encompass Bioscience | , | Shut Down, Dec 2018 |
| Scintillant Bioscience | , | Gone May 2025 |
| , | Rebranded as VivoSim, Apr 2025 | |
| Coley Pharma | , | Acquired by Pfizer |
| LevitasBio | Menlo Park, CA | Cellular Analysis using Magnetic Levitation |
| , | Business filings late, Jan 2023 - Nov 2025 | |
| Noeledge | , | Shut down Jul 2024 |
| Advantagene | , | Renamed Candel Therapeutics |
| Maynard Engineering and Consulting | , | Website down, Dec 2017-Feb 2018 |
| Analytical Services International | London, UK | Bioanalytics, Toxicology, Clinical Services |
| Thornton & Ross | Linthwaite, UK | Consumer products and biologic generics/specialty (derm, bone) |
| West Pharma | Eschweiler, Germany | Pharmaceutical Supplier |
| Nanostream | , | Closed Mar 2008 |
| Meridian Bioscience | Cincinnati, OH | Diagnostics |
| Andelyn Biosciences | Columbus, OH | Cell & Gene Therapy CDMO |
| Targeson | , | Website gone, Mar 2017 |
| , | Acquired by IQVIA | |
| Gennova Bio | Pune, India | mRNA vaccine |
| R1 Therapeutics | San Francisco, CA | Small Molecule Targeting Hyperphosphatemia |
| VM Discovery | , | 20 yr old company with no info on website |
| Evotec | Seattle, WA | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| ReSync Bio | , | Acquired by Benchling 2025 |
| BGI | Cambridge, MA | Sequencing & Bioinformatics services |
| ACROBiosystems | Beijing, China | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Aeonian Pharmaceuticals | , | Website gone, Oct 2019, not a registered business in CA |
| Advanced Genetic Technologies | , | No info |
| BioAscent | Lanarkshire, UK | Drug Discovery Service |
| CMIC | Hoffman Estates, IL | Bioanalytical Contract Research |
| Genpro Research | , | Acquired by Catalyst Clinical Research, Jul 2023 |
| Cell Targeting Inc | , | Bought by Biotime |
| Modulus Discovery | , | Renamed Alivexis, Apr 2024 |
| NX Development | Lexington, KY | Brain Imaging |
| Nemera | Buffalo Grove, IL | Drug Delivery Systems |
| Neovii Biotech | Istanbul, Turkey | Stem Cell Therapy, Biologics |
| SERF SAS | , | Acquired by Stryker, Mar 2024 |
| ExplORer Surgical | , | Acquired by GHX, Oct 2021 |
| Harvard Apparatus Regenerative Technology | Holliston, MA | Regenerative Medicine Research Products |
| Sonceboz | Sonceboz, Switzerland | Wearable Devices |
| AOP Orphan Diseases | Ismaning, Germany | Orphan disease treatments |
| abCRO | , | Acquired by PPD, Apr 2009 |
| Merck | South SF, CA | Small Molecules, Vaccines, Biologics |
| N-Power Medicine | Redwood City, CA | Clinical research and drug development platform for oncology |
| , | Acquired by Certara, Oct 2024 | |
| Virvio | , | Gone Feb 2020 |
| Stimwave | , | Bankrupt, Oct 2022 |
| Aran Biomedical | , | Acquired by Integer, Apr 2022; fka Proxy Biomedical |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Immuno Cure Biotech | Hong Kong, China | Therapeutic Antibodies, DNA Vaccines |
| Cell Mosaic | Woburn, MA | Bioconjugation Tools |
| Omega Diagnostics | Little Port, UK | Diagnostic Tests |
| Advanced Influenza Technologies | , | Acquired by CytoDyn, Jul 2006 |
| Galantos Pharma | , | Sold lead to Nurodyn Aug 2013. Don't believe they are still active |
| Clinitria | Bratislava, Slovakia | Clinical Trial Services & Consulting |
| Salmonics | Brunswick, ME | Fish-derived plasma and serum |
| Provasculon | , | Website Gone, Apr 2014 |
| Spanios | Houston, TX | Patient-derived Organoids for Cancer Research |
| Adienne Pharma and Biotech | Lugano, Switzerland | Biologics, Biosimilars |
| Autoscribe Informatics | Reading, UK | LIMS/Laboratory Software & Services |
| Liposonix | , | Bought by Medicis |
| Harbour BioMed | Suzhou, China | Antibodies and fragments |
| Cynvenio Biosystems | , | Renamed LungLifeAI, May 2019 |
| Piramal | Rabale, India | CDMO |
| DSG | Blue Bell, PA | Clinical Trial Software |
| Taconic Biosciences | Leverkusen, Germany | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Zoll | San Jose, CA | Medical Devices, Defibrillators |
| Autocam Medical | Kentwood, MI | Precision-Machined Medical Devices, Implants |
| Leading BioSciences | , | Merged with Seneca Biopharma to become Palisade Bio, Apr 2021 |
| Flexible Lab Solutions | Sittingbourne, Kent, UK | Lab Automation System |
| Concortis Biosystems | , | Acquired by Sorrento Therapeutics, Dec 2013 |
| |
Martinsried, Germany | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Oncolexis Therapeutics | , | No website Nov 2019 - Feb 2023; single employee on LI in Salt Lake City, not TX Jun 2022 |
| Zimmer Holdings | , | Renamed Zimmer Biomet |
| , | Website down Jan 2026 - May 2026; fka Glauconix | |
| DataHow | Zurich, Switzerland | Digital Bioprocessing Solutions |
| Synpromics | , | Acquired by AskBio, Aug 2019 |
| Nirogy Therapeutics | , | Website down Feb 2023 - Jul 2023; initially called Nirogyone Therapeutics |
| Abiomics | , | Website down May 2023 - Dec 2023 |
| Vertice Pharma | , | Website down Aug 2022 - Jan 2023 |
| Gemini Pharmaceuticals | Commack, NY | Contract Manufacturing & Product Development - OTC |
| Solulink | , | All products acquired by TriLink Biotechnologies |
| Innexus Biotechnology | , | Gone |
| Combs Lab | , | Website gone Dec 2016 |
| Bayer | Bitterfeld, Germany | Small Molecules |
| Optima | Schwaebisch Hall , Germany | Packaging Machines |
| Convergence Medical Devices | , | Renamed Skulpt Health |
| Jet Life Sciences | Hyderabad, India | APIs |
| Biozeus Biopharmaceutical | , | Hijacked website Feb 2022 |
| NEOS Surgery | Barcelona, Spain | Surgical Solutions |
| Sio Gene Therapies | , | Liquidating Feb 2024; fka Axovant Sciences; Spun out small molecules into Arvelle Therapeutics, Feb 2019 |
| Cytiva | Burnaby, BC | Cell Culture Products |
| Novatim Immune Therapeutics | Zhejiang, China | Cancer Immunotherapy, CAR-T, Bispecific Antibodies |
| Vela Laboratories | Vienna, Austria | GMP Contract Services |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| M3 Wake Research | Newport Beach, CA | Clinical Research |
| Vascular Perfusion Solutions | San Antonio, TX | Oxygenated perfusion cardiac transport device |
| Springborn Laboratories | , | Acquired by Charles River Labs, Oct 2002 |
| AroCell | , | Renamed IDL Diagnostics, May 2025 |
| Cerebroscience | , | One employee, website gone |
| Correvio | , | Acquired by Advanz Pharma, May 2020, $76M |
| GenePath Diagnostics | Maharashtra, India | Molecular Diagnostics |
| Famar | Alcorcon, Spain | Contract Manufacturing - Small Molecules |
| Syntagon | , | Acquired by Ardena, May 2018 |
| Selux Diagnostics | Charlestown, MA | Infectious Disease Phenotyping |
| Stemnovate | Cambridge, UK | Research Cells |
| Sciwind Biosciences | Hangzhou, China | Oral peptide delivery |
| Onconova Therapeutics | , | Merged with Trawsfynydd Therapeutics to become Traws Pharma, Apr 2024 |
| ArrayUS Technologies | Toronto, ON | Non-invasive focused ultrasound therapy |
| , | Acquired by Stryker, Sep 2024 | |
| Fractal Therapeutics | Cambridge, MA | Small Molecule Research |
| Annias Immunotherapeutics | , | No progress, not registered in CA, website broken and under construction for years |
| EOC Pharma | Westlake Village, CA | In licensing for Chinese market |
| Andara Life Science | , | Acquired by CyberKinetics, Feb 2006 |
| Dynatherm Medical | , | Shut down 2012 or later |
| Faxitron Bioptics | , | Acquired by Hologic, Jul 2018, $85M |
| AliveCor | Mountain View, CA | Heart Monitor with App |
| IGXBio | , | Website down May 2021 - Sep 2021 |
| Squarex | , | Gone as of Oct 2021 |
| CorDx | San Diego, CA | Diagnostics |
| Valinor Pharma | , | Acquired by Grunenthal, Jul 2024, $250M |
| Rheostat Therapeutics | , | Renamed Caraway Therapeutics, Oct 2019 |
| Stemcentrx | , | Bought by AbbVie, Apr 2016, $5.8B +$4B milestones |
| Particella | San Francisco, CA | Oral lipid nanoparticle technology to deliver nucleic acids to the intestinal epithelium |
| Azico Biophore | Hyderabad, India | API Manufacturing |
| Pion | Billerica, MA | Dissolution Data |
| MicroMedicine | , | Website down Jan 2021 - May 2021 |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EDDA Technology | Princeton, NJ | Computer-assisted Radiology |
| Biomex | Heidelberg, Germany | Cells, Research Products |
| Faulk Pharmaceuticals | , | Bought by Panther Biotechnology, Jul 2015, stock plus royalty |
| Meritage Pharma | , | Bought by Shire, Feb 2015, $70M +$175 milestones |
| Fresenius Kabi | Gqeberha, South Africa | Contract Manufacturing |
| EpsilenBio | , | Acquired by Chroma Medicine, Nov 2021 |
| TScan Therapeutics | Waltham, MA | T Cell Therapies |
| Advita Ortho | Gainesville, FL | Orthopedic Implants |
| LXRepair | , | Website down Apr 2025 - Jul 2025 |
| Platine Pharma Services | , | Bought by ABL inc, Jul 2014 |
| Hypnion | , | Acquired by Eli Lilly, Mar 2007 |
| Photonion | Schwerin, Germany | Analytical Equipment |
| Liquidyne | Wheat Ridge, CO | Single-use & sanitary process equipment for fluid transfer, measurement, & control |
| Fortitude Biomedicines | Waltham, MA | Bispecific Antibody |
| Taconic Biosciences | Cambridge City , IN | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Eppendorf | Hamburg, Germany | Wide Range of Scientific Products |
| Lentigen | , | Acquired by Miltenyi Biotech, Apr 2014 |
| AzurRx | , | Merged into First Wave Bio |
| Healthgen Biotechnology | Wuhan, China | HAS, Growth Factors |
| Aether Biomedical | Poznan, Poland | Bionic Hands |
| Contract Pharmaceuticals | Mississauga, ON | Liquid and semi-solid pharmaceutical products |
| Cyberonics | , | Merged with Sorin, renamed LivaNova, Oct 2015 |
| Shantha Biotech | , | Acquired by Sanofi, Jul 2009, $784M |
| Aldevron | Madison, WI | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Sihuan Pharmaceutical | , | Website down Nov 2024 - Apr 2025 |
| Scope Fluidics | Warsaw, Poland | Diagnostics |
| Amadix | Valladolid, Spain | Diagnostic development |
| UVision 360 | , | Renamed Luminelle |
| BioSpring | Tokyo, Japan | Manufacturing & Analytical Services |
| Laza Medical | Campbell, CA | AI-Powered Robotically-Assisted Imaging |
| XableCath | , | Website down Feb 2022 - Apr 2022 |
| Shilps Sciences | , | Website down Feb 2025 - Jul 2025 |
| Cytori Therapeutics | , | Renamed Plus Therapeutics, Jul 2019 |
| Inotek Pharmaceuticals | , | Rocket Pharmaceuticals Reverse Merged into Inotek, Sep 2017, took name Rocket |
| Daiichi Sankyo | Tokyo, Japan | Small Molecules |
| ApeX Therapeutics | , | Changed name to Apexian Pharmaceuticals, Oct 2016 |
| PAQ Therapeutics | Burlington, MA | Restoring health and curing disease through autophagy |
| Bionovo | , | Sold Assets, Shut down operations, may exist as a shell |
| Torpedo Diagnostics | , | Last annual report filed Mar 2019 as of Aug 2021; Website not active Nov 2019 - Aug 2021 |
| Biovays | , | Website Gone |
| Kembiotix | , | No info, Aug 2022 |
| Ranger Biotechnologies | , | Website down Jun 2020 - Sep 2020 |
| Brillian Pharma | Edison, NJ | Innovative Pediatric Dosage Forms |
| Altona Diagnostics | Hamburg, Germany | PCR based diagnostics, molecular diagnostics |
| Inflazyme Pharmaceuticals | , | Sold assets, Sep 2007 |
| Viracor-IBT | , | Renamed Viracor Eurofins; Bought by Eurofins, May 2014 |
| CONMED | Chihuahua, Mexico | Surgical, Medical Devices |
| Alcon | Fort Worth, TX | Eye-Care Products |
| Cardiawave | Levallois-Perret, France | Non-invasive ultrasound therapy for the treatment of calcific aortic stenosis |
| |
Tittmoning, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| Florence Heatlthcare | Atlanta, GA | Clinical Trial Platform |
| ModiQuest | , | Acquired by ImmumoPrecise, Apr 2018 |
| Bardy Diagnostics | , | Acquired by Hillrom, Sep 2021 |
| AnorMED | , | Acquired by Genzyme, Oct 2006 |
| cGMPnow | Boulder, CO | Turnkey GMP Systems |
| Thirona | Nijmegen, Netherlands | Clinical Software |
| Spherics | , | Bankrupt |
| Receptos | , | Bought by Celgene, Jul 2015, $7.2B |
| |
Glasgow, UK | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Shenogen Pharma | Beijing, China | Small Molecules, Biologics, Viral |
| Bend Research | , | Acquired by Capsugel, Sep 2013 |
| Roche | Grenzach-Wyhlen, Germany | Small Molecules |
| Stallergenes | , | Merged with Greer Labs to become Stallergenes Greer |
| CBio | , | Merged with Inverseon to become Invion, Aug 2012 |
| Tempus | Chicago, IL | AI-driven Drug Discovery, Devices |
| Cornerstone Therapeutics | , | Acquired by Chiesi Farmaceutici, Feb 2014 |
 |
BPG, USA | This is a Premium Listing - upgrading may double or triple your referrals. Try it out. |
| Gamma Therapeutics | , | Gone |
| Curavit Clinical Research | Boston, MA | Decentralized Clinical Trial Platform |
| ATON | Shanghai, China | CDMO |
| Statera Therapeutics | , | Shut down Jan 2022 |
| Heraeus Medical | Changshu, China | Medical Devices |
| GamaMabs | , | Website down Jul 2022 - Nov 2022 |
| BrainXell | Madison, WI | Neuronal Research products & services |
| Ankrin Therapeutics | , | Website down Apr 2025 - Sep 2025 |
| Certis Oncology Solutions | San Diego, CA | Cancer therapy recommendation platform, preclinical CRO |
| Astellas | Takahagi, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Mabpharm (1) | , | Acquired by Cipla, Jul 2014 |
| Getinge | Antalya, Turkey | Medical Technology |
| Brogan Pharma | , | Acquired by IMS Health, 2010 |
| OFD Biopharma | Albany, OR | Lyophilization |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| CorTechs Labs | , | Renamed Cortechs.ai |
| AB2 Bio | Lausanne, Switzerland | Diagnostic |
| AboleIIs Pharma | Gosselies, Belgium | Monoclonal Antibody |
| HebeCell | Natick, MA | Cell Therapies |
| Parse Biosciences | Seattle, WA | Single Cell Sequencing |
| EAG Laboratories | Singapore, Singapore | Analytical & Synthesis Services |
| Preferred Cell Systems | Colorado Springs, CO | Assay kits and cell culture media for stem cell research, cellular therapy and in vitro toxicity testing |
| Kinaxo | , | Bought by Evotec |
| Northern Antibiotics | , | Website gone Feb 2025 - May 2025 |
| Forge Biologics | Grove City, OH | Biologics |
| JADBio | Aarhus, Denmark | Machine Learning Data Analysis |
| August Therapeutics | , | Shut down Dec 2024 |
| Biorasis | , | Founders and other employee gone, Dec 2021 |
| Brillian Pharma | Monmouth Junction, NJ | Innovative Pediatric Dosage Forms |
| Chiltern | , | Acquired by LabCorp, $1.2B, Jul 2017 |
| Conduit Pharmaceuticals | , | Pivoted to partnerships and outlicensing, Aug 2025 |
| Diversatek | , | Website down Jun 2021 - Oct 2021 |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Vetex Medical | , | Acquired by Surmodics, Jul 2021, $40M + $10.5M milestones |
| Alantos Pharmaceuticals | , | Bought by Amgen 2007 |
| Rommelag | Baden-Würrtemberg, Germany | Blow-fill-seal, aseptic packing systems |
| Chiron | , | Bought by Novartis |
| V-gene | , | Website gone, Aug 2017 |
| Abeta | , | Assets bought by The Genetics Company, Jun 2003 |
| Fresenius Kabi | Brunna, Sweden | Contract Manufacturing |
| Imol Radiopharmaceuticals | , | No website May 2023; 2017 SBIR, run by a UVA professor Aug 2021 |
| Optiscan Imaging | Melbourne, Australia | Single-Cell Imaging |
| Cellenkos | Houston, TX | Cord Blood Cell Therapy |
| Cradle Bio | Amsterdam, Netherlands | AI Protein Design |
| Nabriva Therapeutics | , | Shutting down Mar 2023 |
| Lumenis | Beijing, China | Energy-based medical treatments |
| PAN Medical | , | Bought by Zavation, Sep 2018 |
| Cytocentrics | , | Renamed CytoBioscience, Dec 2016 |
| Sampling Human | Berkeley, CA | Single cell biomarkers |
| Cellular Therapeutics Ltd | , | Dissolved, Jun 2024 |
| Lithera | , | Changed company name to Neothetics, Aug 2014 |
| Sinobioway | , | |
| Planet Biotechnology | , | Business filings late Sep 2022 - Dec 2024; No news 2020-2024 |
| Wave 80 Biosciences | , | Business filings late May 2023 - Feb 2025 |
| Ablynx | , | Acquired by Sanofi, Jun 2018, $4.8B |
| Trevi Therapeutics | New Haven, CT | Small Molecules |
| Marker Gene Technologies | , | Acquired by Abcam, Mar 2020 |
| Sierra Neuropharmaceuticals | , | Not active |
| Averna Therapeutics | Ness Ziona, Israel | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Precision IBD | , | Renamed Prometheus Biosciences, Sep 2019 |
| Flow Paradigm | , | Website down Nov 2023 - Apr 2024 |
| Tallac Therapeutics | Burlingame, CA | Novel Cancer Immunotherapies |
| VasoNova | , | Acquired by Teleflex Medical |
| Tolerx | , | Shut Down 2011 |
| Alcor Bioseparations | , | Shut down Nov 2018 |
| Sinovac Biotech | Beijing, China | Vaccines |
| Providence Clinical Research | , | Acquired by Velocity Clinical Research |
| Fresenius Kabi | Qui Nhon, Vietnam | Contract Manufacturing |
| Bionix | Maumee, OH | Ear and Nasal Devices |
| Precipio Diagnostics | New Haven, CT | Oncology Diagnostics |
| CIMEX Pharma | , | Acquired by Acino, 2004 |
| Sonexa Therapeutics | , | Closed 2013 |
| MabQuest | , | No website Dec 2018 - May 2023 |
| HEI Life Sciences | , | Website gone, Sep-Nov 2017 |
| Medi-Tate | , | Acquired by Olympus, May 2021 |
| DDL | Edison, NJ | Device Testing |
| Accelerate Diagnostics | Tucson, AZ | In vitro diagnostics focused on drug-resistant organisms |
| Celemics | , | Gone Jul 2018 |
| Circe Biomedical | , | Acquired by ICN Pharmaceuticals, Oct 2002 |
| Axbio | Santa Clara, CA | Biochips |
| EVA Pharma | Giza, Egypt | Branded Generics |
| Kite Pharma | Santa Monica, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Wheeler Bio | Oklahoma City, OK | Biomanufacturing |
| Eleven Biotherapeutics | , | Changed name to Sesen Bio, May 2018 |
| bioeq | , | Website down Dec 2022 - Apr 2023 |
| Avatar Medical | Mountain View, CA | Surgical Visualization |
| Strides | Bangalore, India | Niche generics and bio-pharmaceuticals |
| Speech Buddies | San Francisco, CA | Speech therapy device |
| Amador Bioscience | Pleasanton, CA | Consulting, Lab Service, Clinical Trial Management |
| Therics | , | Acquired by Integra |
| Ziarco | , | Bought by Novartis, Dec 2016 |
| Alvea | , | Shut down Oct 2023 |
| ViCentra | Utrecht, Netherlands | Insulin Pump & Technology |
| List Biological Laboratories | Campbell, CA | Bacterial Toxins, Contract Manufacturing |
| TopAlliance Biosciences | Rockville, MD | Monoclonal Antibody |
| Synaffix | Oss, Netherlands | Antibody-drug combination delivery technology |
| Catylix | , | Shut down Oct 2021 |
| Vista Scientific | , | Shut down Dec 2015 |
| ProZyme | , | Acquired by Agilent, Aug 2018 |
| Clyde Biosciences | Lanarkshire, UK | CRO focused on safety pharmacology and screening for cardiac liabilities |
| Sandhill Therapeutics | , | LI page gone Nov 2023, no info on website 2020-2024 |
| Epinomics | , | Acquired by 10X Genomics, Aug 2018 |
| Conor Medsystems | , | Acquired by Johnson & Johnson, Nov 2006, $1.4B |
| ASC Biosciences | , | Business pulled in CA, Sep 2017 |
| DaCapo Brainscience | Cambridge, MA | Drug Discovery Platform for neuro |
| Amos Scientific | Melbourne, Australia | Histopathology Instruments |
| Jerusalem Pharmaceuticals | Ramallah, Israel | Drugs for Middle East Region |
| AustarPharma | , | Now Bostal Pharma, Feb 2025 |
| Kalypsys | , | Gone |
| American Drug Co. | , | Renamed Five Star Products |
| Plus Therapeutics | San Antonio, TX | Radiotherapy |
| Cobalis | , | Basically Bust |
| Cardiosense | Chicago, IL | Digital Biomarker Platform |
| Getinge | Merrimack, NH | Medical Technology |
| Infusion Pharma Consulting | , | Website down Dec 2022 - Apr 2023 |
| Worldwide Clinical Trials | Moscow, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Morphogen-IX | , | Acquired by Centessa Pharmaceuticals |
| Vivonda Medical | , | Renamed Neuspera Medical, Aug 2015 |
| Chronos Imaging | Aurora, IL | Medical X-Ray Tubes |
| Zuma Biosciences | , | Company Gone |
| TapImmune | , | Merged into Marker Therapeutics, Oct 2018 |
| EnPlusOne Biosciences | Watertown, MA | Enzymatic RNA Synthesis Platform |
| LGM Pharma | Rosenberg, TX | Sourcing, warehousing & distribution of quality CGMP APIs to pharma & biotech companies. |
| Biopharma Informatic | Houston, TX | Site Management Clinical Research Organizations |
| Cortexyme | , | Renamed Quince Therapeutics, Jul 2022 |
| NyLa Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Ofni Systems | Raleigh, NC | Regulatory Compliance Solutions |
| Halda Therapeutics | New Haven, CT | Regulated Induced Proximity Targeting Chimeras |
| Avelas Biosciences | , | Website down Nov 2023 - Mar 2024 |
| Smoke Free Therapeutics | , | Renamed NFL Biosciences |
| New York Global Innovations | , | Changed name to Artermis Therapeutics, Dec 2016 |
| NemaGen Discoveries | Princeton, NJ | Therapies for allergic inflammation and mast cell-related diseases |
| HalioDx | , | Acquired by Veracyte, Aug 2021 |
| ARC Regulatory | Belfast, UK | Regulatory and clinical research organization, dedicated to supporting companies in the in vitro diagnostic and precision medicine sector. |
| Johnson & Johnson MedTech | Raynham, MA | Medical Devices |
| Optovue | , | Renamed Visionix Sep 2021 |
| Rubedo Life Sciences | Sunnyvale, CA | Age-related drug discovery platform |
| Kendall Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| BBT Biotech | Baesweiler, Germany | Bio-derived APIs |
| Arsenal Products | , | Website down Dec 2021 - Apr 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Molecular Health | Heidelberg, Germany | Data and analytics for precision medicine |
| Verseau Therapeutics | , | No annual reports filed Mar 2023 - Jun 2025 |
| Carmine Therapeutics | Singapore, Singapore | Medicines based on red blood cell extracellular vesicles (RBCEVs), for the delivery of novel therapeutic modalities that include nucleic acids |
| NimaGen | Nijmegen, Netherlands | DNA sequencing reagents, capillary electrophoresis kits, and patented Reverse Complement PCR (RC-PCR) library prep solutions |
| Najit Technologies | , | Dated website, no updates Sep 2019 - Feb 2025 |
| VivaCell Biotechnology | Denzlingen, Germany | In vitro and ex vivo research services |
| Venthera | , | Folded into BridgeBio, Sep 2023 |
| Sandoz | Boucherville, QC | Generics, Biosimilars |
| Microbiologics | St. Cloud, MN | Diagnostics, Services |
| bioMerieux | Durham, NC | Diagnostics |
| Tissuemed | , | Website down Feb 2024 - Jul 2024 |
| ProtonDx | London, UK | Diagnostics |
| RiboCor | , | Website down Aug 2019 - Oct 2019; fka Bioenergy, changed name in 2012, subsidiaries RiboCor Pharmaceuticals & Viacell |
| Argus Biomedical | , | Products sold to Cooper, Feb 2004 |
| FlowAid Medical Technologies | , | Website down Feb 2024 - Jul 2024 |
| Ignota Labs | Cambridge, UK | Rescuing Drugs Using AI |
| IONTOX | , | Acquired by LifeNet Health LifeSciences, Aug 2022 |
| AlphaMol Science | Allschwil, Switzerland | Therapeutics targeting GPCR |
| DiaCarta | Shanghai, China | Molecular Diagnostics Tests |
| Gencia Biotech | , | Website gone Apr 2020 - Oct 2020 |
| Nemera | La Verpillière, France | Drug Delivery Systems |
| LGC Biosearch Technologies | Novato, CA | Reagents, Probes, Oligonucleotides |
| Mithra Pharmaceuticals | , | Bankrupt Jun 2024, selling assets |
| CytomX Therapeutics | South SF, CA | Protease-Activated Antibodies, 'Probodies' |
| Thermo Fisher | Waltham, MA | Lab Supplies and Equipment |
| AHN Biotechnologie | Nordhausen, Germany | Liquid handling consumables |
| apconix | Cheshire, UK | Toxicology & DMPK Consultancy |
| Axplora | Chasse-sur-Rhône, France | CDMO Services for APIs & intermediates |
| TheWell Bioscience | Monmouth Junction, NJ | 3D Hydrogel Platform |
| Mechatronics Instruments | Zwaag, Netherlands | Blood Analysis Devices |
| Precise Bio | , | Gone 2023 |
| Reflectance Medical | , | Acquired by Sotera, Feb 2015 |
| OLS Omni Life Science | Aabenraa, Denmark | Cell Research Products |
| Catalent | Schorndorf, Germany | Dosage Form Development |
| Ervaxx | , | Renamed Enara Bio, Jun 2020 |
| Oncore Pharma | , | Website down Oct 2021 - Mar 2022 |
| Quagen Pharmaceuticals | West Caldwell, NJ | Contract Manufacturing |
| Altheus Therapeutics | , | Seems Gone, no employees on LI, website gone |
| , | No news 2021 - Sep 2025 | |
| Turing Medical | St. Louis, MO | Neuromodulation |
| Photys Therapeutics | Waltham, MA | Small Molecules to Modify Protein Function |
| Elion Labs | , | Acquired by KBI Biopharma, Jan 2018 |
| Ras Labs | Boston, MA | Electroactive polymers for synthetic muscles |
| MOgene | St. Louis, MO | Genomic Services |
| AccelBio | Farmingdale, NY | Cell Analysis Robotics, Cells |
| PeriCor Therapeutics | , | Website Gone |
| Bioptimus | Paris, France | AI Drug Discovery |
| Wilmington PharmaTech | Newark, DE | Integrated CRO/CMO Clinical Drug Development Services |
| Pharm-Olam | , | Merged with CATO SMS, Jan 2022 |
| SMC Biotechnology | , | Website gone, Aug-Oct 2017 |
| Quibim | Madrid, Spain | Ai for Imaging, Radiomics, Medical Uses |
| X-Bolt Orthopedics | Dublin, Ireland | Orthopedic trauma implants |
| Promedior | , | Acquired by Roche, Feb 2020 |
| IntelligentMDx | , | Shut down Feb 2015 |
| HeartFlow | Mountain View, CA | Coronary heart diseases assessment |
| Kineta | , | Acquired by TuHURA Biosciences, Jun 2025; Reverse merged into Yumanity, Jun 2022 |
| Nested Therapeutics | Cambridge, MA | Non-degrading, molecular glue |
| STA Pharmaceutical | Changzhou, China | API manufacturing |
| Biomeva Manufacturing | , | Acquired by Asahi Glass, Nov 2016; Now part of AGC Biologics |
| ReGenesys | , | Website copyright 2012 as of Apr 2021 |
| Cormica | London, UK | Analytical and Testing Services for Medical Devices, Combination Products, Pharmaceutical |
| Zionexa | , | Acquired by GEHealthcare, May 2021 |
| DTx Pharma | , | Acquired by Novartis, Jul 2023, $500M + $500M milestones |
| Namocell | , | Acquired by Bio-Techne, Jul 2022 |
| ILLUSTRATUM | , | Website taken over Mar 2020 |
| Altasciences | Laval, QC | Contract Research |
| NeuroFx | , | Renamed Theratome Bio |
| LeukoSite | , | Acquired by Millennium 1999 |
| AcroMetrix | , | Acquired by Life Technologies Jan 2010 |
| veranova | Devens, MA | CDMO - APIs, Biologics |
| , | Acquired by IQVIA | |
| Sciomics | Neckargemünd, Germany | Custom microarrays |
| Ergomed | Raleigh, NC | Clinical Research |
| , | Website down Sep 2025 - Dec 2025 | |
| Amgen | Singapore, Singapore | Continuous Biologics processing |
| , | Renamed Valion Bio, Apr 2026 | |
| Athera Biotechnologies | , | Website gone Sep 2022, Employees all gone |
| Novo Nordisk | Måløv, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| Alavita Pharmaceuticals | , | Shut down Oct 2014 |
| Ascential Medical & Life Sciences | Ada, MI | Automation Technologies |
| Dfine | , | Acquired by Merit Medical, Jul 2016, $98M |
| CanZx Biotherapeutics | , | No news since 2018 as of Oct 2023, not registered in WA; Residential address, Dec 2021 |
| Multitude Therapeutics | Redwood City, CA | Antibody Discovery Arrays, ADCs |
| American Oriental Bioengineering | , | Stopped reporting to SEC, shareholders suing in 2016 |
| Applied Biological Materials | Richmond, BC | Molecular biology and general lab products |
| Alliance Pharmaceuticals | Wiltshire, UK | Acquisition and licensing |
| Lumora | , | Bought by Erba Diagnostics Sep 2015, Rebranded Erba MDX |
| Elite Pharmaceuticals | Northvale, NJ | Generic Small Molecules |
| Retroscreen Virology Group | , | Renamed hVIVO |
| Cellink | Blacksburg, VA | Bioprinting |
| Macopharma | Tourcoing, France | Bodily Fluid Handling Solutions |
| , | Renamed Motive Health, Jul 2023 | |
| Acute Innovations | , | Acquired by Acumed, Mar 2020 |
| Cardiac Science | , | Acquired by Zoll, Aug 2019 |
| Phenomix | , | Shut Down 2011 |
| emp Biotech | Berlin, Germany | labeling kits, fine chemicals to specialty reagent, services |
| ScarX Therapeutics | , | Website Gone, May 2018 |
| Asieris Pharmaceuticals | Palo Alto, CA | Small Molecules, Drug-Device Comvo Product |
| Averna Therapeutics | Watertown, MA | Developing genomic medicines that insert therapeutic genes into safe harbors within the DNA |
| Slingshot Biosciences | Emeryville, CA | Synthetic Cells |
| Evolve BioSystems | , | Renamed Infinant Health |
| Argonaut Therapeutics | , | Merged with Celleron Therapeutics, Jan 2023, to become InegneOx Therapeutics |
| BiondVax Pharmaceuticals | , | Renamed Scinai Immunotherapeutics, Sep 2023 |
| ApoGen Biotechnologies | , | Website down Oct 2022 - Mar 2023 |
| Novartis | Mexico City, Mexico | Small Molecules, Vaccines, Biologics |
| Clintec | , | Acquired by IQVIA, Dec 2018 |
| , | Renamed Silthera, Apr 2026 | |
| Kalera Medical | , | Renamed Calyxo, Jun 2020 |
| Carbogen Amcis | Bubendorf, Switzerland | API Delivery Gel |
| Arcus Biosciences | Hayward, CA | Cancer Immunotherapies |
| Prommune | , | |
| Eargo | San Jose, CA | Hearing Aids |
| Tourmaline Bio | New York, NY | Antibody Therapies |
| Adagio Medical | Laguna Hills, CA | Continuous Lesion Ablation System |
| Altan Pharma | , | Acquired by Ethypharm |
| Synthekine | Menlo Park, CA | Engineered Cytokines |
| VDDI Pharmaceuticals | , | Website copyright 2001 in Nov 2019 |
| SciBac | , | Website Down Nov 2022 - Apr 2023 |
| Alcobra Pharma | , | Acquired by Arcturus, Sep 2017 via reverse merger |
| Cistron Biotechnology | , | Acquired by Celltech Group, Nov 2000 |
| OrganOx | Oxford, UK | Organ Transportation Technology |
| Southern Star Research | Gordon, Australia | Clinical Research & Related Services |
| Kythera Biopharmaceuticals | , | Bought by Allergan, Oct 2015, $2.1B |
| Pillar5 Pharma | Arnprior, ON | Contract Everything |
| Amphiprotech | Shanghai, China | Eye Drops, Pain Treatment, Aerosol Delivery |
| , | Website gone Feb 2026 - Jun 2026 | |
| R&D Systems | Minneapolis, MN | Specialty Biologics |
| Variantyx | Framingham, MA | Clinical Diagnostic Services |
| 10x Science | San Francisco, CA | Protein Characterization Software |
| Scantox Neuro | Grambach, Austria | Neuro CRO |
| Halo-Bio | , | No longer seems active, Sep 2017 |
| Empirico | San Diego, CA | Genetics-Based Drug Discovery |
| Tiburio Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Niagara Biosciences | , | No info, Aug 2022 |
| Acretia | , | Gone |
| ICON plc. | Brentwood, TN | Clinical Trials, Consulting |
| Biotheneum | , | Gone |
| AilseVax | , | Renamed AilseBio, Nov 2024 |
| Innoforce | Ruggell, Liechtenstein | Software development in ENT and ophthalmology |
| Lightspeed Microscopy | , | Renamed Alpenglow Biosciences, Feb 2022 |
| DNAx | , | Acquired by Schering-Plough, Apr 1982 |
| CapsoVision | Saratoga, CA | Endoscopy Diagnosis Visualization |
| Visitube | , | No website Mar 2020 |
| Genibet Biopharmaceuticals | , | Acquired by Recipharm, Feb 2022 |
| InnoCare | Beijing, China | Cancer Treatments |
| RNAConnect | Branford, CT | Enzymes for RNA Work |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Veritas Genetics | , | US ops suspended, sold off Dec 2019 |
| NovellusDx | , | Renamed Fore Biotherapeutics, Feb 2021 |
| Genetika+ | , | Renamed NeuoKaire, May 2024 |
| Root Lines Technology | , | Renamed Samabriva |
| Metrohm | Riverview, FL | Lab Data Management Software |
| Angiocrine Bioscience | San Diego, CA | Cellular Therapy |
| Vitality Biopharma | , | Website gone Dec 2021, not registered in CA; fka Stevia First - was a Stevia company until 2016 |
| Lampire Biological Labs | Pipersville, PA | Antibody & Biologics Services |
| Cardiokine | , | Acquired by Cornerstone Therapeutics 2011 |
| Bioquanta | , | Gone 2013 |
| Censa Pharmaceuticals | , | Acquired by PTC Therapeutics, Jun 2020 |
| Swift Biosciences | , | Acquired by Integrated DNA Technologies, Mar 2021 |
| Opiant Pharmaceuticals | , | Acquired by Indivior, Mar 2023, $145M |
| Shanghai Sunway Biotech | Shanghai, China | Biologics |
| 4HF Biotec | Freiburg, Germany | Anti-cancer Treatments |
| Cage Pharma | , | Business no longer active in MD, Nov 2022 |
| Insight Biopharmaceuticals | , | Liquidated, sold to PharmaEstica Manufacturing, Jul 2017 |
| Acolyte Biomedica | , | Acquired by 3M, Feb 2007 |
| Finch Therapeutics | Boston, MA | Microbiological Therapy |
| Mosaic Biosciences | Boulder, CO | Materials to Support Tissue Regeneration |
| Innovotech | Edmonton, AB | Biofilm Contract Research & Development |
| Dr. Reddy's Laboratories | Princeton, NJ | Small Molecules, Custom Pharma Services |
| Tevogen Bio | Warren, NJ | T Cell Therapy for Covid |
| NeuroBo Pharmaceuticals | , | Renamed MetaVia, Nov 2024 |
| , | Acquired by Abbott, Apr 2023, $890M | |
| Pharmaron | Coventry, RI | API Manufacturing |
| PYC Therapeutics | Nedlands, Australia | Peptide drug discovery |
| Ansaris | , | Gone |
| Exicure | , | Only employee is accountant trying to dispose of assets, Dec 2023; fka AuriSense Therapeutics |
| Gadeta | , | Closed Feb 2024; Acquired by Clade Therapeutics, Oct 2023 |
| OmniTier | San Jose, CA | High Performance Computing Solutions |
| Assembly Biosciences | South SF, CA | Small Molecule Antivirals |
| Piper Therapeutics | , | Website gone May 2020 |
| Omrix Biopharmaceuticals | , | Bought by Ethicon |
| , | Website down Jan 2026; LI gone Nov 2023 | |
| Amphivena Therapeutics | , | Website down Oct 2022 - Mar 2023 |
| Dexcom | San Diego, CA | Glucose Monitors |
| Enzerna Biosciences | , | Employees gone, Website down Oct 2024 |
| Deep Breath Intelligence | Rotkreuz, Switzerland | High-resolution mass spectrometry/ AI-based tools to analyze breath |
| Aspire Pharma | Somerset, NJ | Soft gel, capsule CDMO |
| Irvine Clinical Research | Irvine, CA | Clinical Trials |
| Katena Products | , | Acquired by Corza Medical, Dec 2021 |
| PopulationGenetics | , | No longer active, just looking to license their technology, website gone Apr 2019 |
| Axonyx | , | Merged with TorreyPines Therapeutics, Jun 2006 |
| Fresh Tracks Therapeutics | , | Dissolving Sep 2023; fka Brickell Biotech; Went public via Reverse Merger with Vical, Jun 2019; Moved from FL |
| Celonic | Heidelberg, Germany | Biologics Contract Work |
| Sequoia Vaccines | St. Louis, MO | Antibacterial Small Molecules, Vaccines for UTI |
| Stealth Therapeutics | , | Gone |
| Worldwide Clinical Trials | Belgrade, Serbia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Astrogenetix | , | Parent company no longer lists as an entity, last news 2012 as of Jan 2021 |
| Akros Pharma | Princeton, NJ | Develops products for JT Pharmaceuticals |
| ProfoundBio | , | Acquired by Genmab, May 2024, $1.8B |
| Neuromod Devices | Dublin, Ireland | Bimodal Neuromodulation Device |
| Pfizer | Buenos Aires, Argentina | Solid Oral Dosage Forms |
| Barinthus Biotherapeutics | Germantown, MD | T cell immunotherapy for Vaccines |
| NanoVision Diagnostics | , | Funding in 2014, no website or news since then as of Aug 2021 |
| Accuray | Sunnyvale, CA | Directed Radiation Therapy |
| Axys Pharmaceuticals | , | Acquired by Celera, Nov 2001, $174M |
| Braeburn Pharmaceuticals | Plymouth Meeting, PA | Out licensing |
| Niveus Medical | , | Closed Dec 2017 |
| PlantForm | Toronto, ON | Plant-Derived Biosimilars, Biodefense |
| Rinri Therapeutics | Sheffield, UK | Cell Therapy |
| SinoCellTech | , | Website down Nov 2023; Pipeline page hacked, Oct 2023 - Jan 2024 |
| Neuro3d | , | Acquired by Evotec, Mar 2007 |
| YM Biosciences | , | Bought by Gilead Dec 2012 |
| AGI Therapeutics | , | Bought by Videra |
| MedAlliance | , | Acquired by Cordis, Oct 2023, $235M |
| Activiomics | , | Acquired by Retroscreen Virology Group, Mar 2014 |
| Deltagen | , | Website gone Aug 2018; Was outdated before then |
| ProPharma Group | Deerfield, IL | Consulting |
| , | Acquired by Roche, Jan 2025, $1.5B; Spinout of Transposagen Biopharmaceuticals | |
| Cypress Pharmaceuticals | , | Acquired by Pernix |
| MPE | Milwaukee, WI | Design and manufacturing partner to the Medical device industry |
| Foresight Diagnostics | Boulder, CO | Cancer Diagnostics |
| Charter Medical | Winston-Salem, NC | Single-used Devices |
| Solventum | St. Paul, MN | Medical devices, health IT platforms, dental solutions, purification and filtration products |
| DDi | Princeton, NJ | Clinical Software |
| Acutis Biosciences | Hicksville, NY | Biomarker Discovery |
| Lonza | Slough, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| Centaur Labs | Boston, MA | Medical data labeling including classification and segmentation for X-ray, CT, MRI, ultrasound, image, video, text etc. |
| Apnimed | Cambridge, MA | Sleep Apnea Drugs |
| EvON Medics | Ellicott City, MD | Medical Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Vedantra Pharmaceuticals | , | Renamed Elicio Therapeutics, ~May 2019 |
| Rhoshan Pharmaceuticals | , | Website down Oct 2021 - Mar 2022 |
| Nihon Kohden | Rosbach, Germany | Medical Electronic Equipment |
| , | Website taken over, Nov 2025 | |
| Endpoint Clinical | Raleigh, NC | Clinical Trial IRT Solutions |
| BioMmune | , | Changed name to Pascal Biosciences, Mar 2017 |
| Stipple Bio | Cambridge, MA | Unlocking cellular profiling and target discovery with epitope resolution |
| Tarbis Farma | , | Acquired by Hetero Labs, Jan 2019 |
| Prilenia Therapeutics | Herzliya , Israel | Treatments for neurodegenerative and neurodevelopmental disorders |
| Biowarn | , | Gone |
| Arthrex | Santa Barbara, CA | Arthroscopy Devices |
| Vitalograph | Buckingham, UK | Respiratory Diagnostics, Clinical Trials |
| Integer | Minneapolis, MN | Medical & Surgical Devices |
| Singular Genomics | San Diego, CA | Genomics |
| Teleflex Medical | Vianen, Netherlands | Surgical and Medical Devices |
| Apex Bioscience | , | Acquired by CuraCyte, fka Strohtech |
| ThermaSolutions | White Bear Lake, MN | Intraperitoneal Hyperthermia Device |
| Ascelia Pharma | Malmö, Sweden | MRI Imaging Drug |
| UCB Pharma | Morrisville, NC | Small Molecules, Biologics |
| Glenmark | Mahwah, NJ | Generic Small Molecules |
| CANbridge Pharmaceuticals | Beijing, China | Contracts with western companies to bring them to Asian markets |
| Arisyn Therapeutics | , | Bankrupt, Dec 2012 |
| Horus Pharma | Nice, France | Generic Ophthalmology, Dermatology Products |
| Quethera | , | Bought by Astellas, Aug 2018, up to $109M |
| CVRx | Minneapolis, MN | Implantable Hypertension Device |
| Biodiscovery | , | Acquired by Bionano Genomics, Oct 2021 |
| UFP technologies | Newburyport, MA | Device Design & Packaging |
| EyeKor | , | Renamed Merit CRO, Apr 2021 |
| Carbylan Therapeutics | , | Merged into KalVista Pharmaceuticals, Jun 2016 |
| Aixial Group | Timisoara, Romania | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Pioneer Surgical | , | Merged with RTI Biologics to become RTI Surgical |
| CRF Bracket | , | Renamed Signant Health, 2018; formed out of Merger between CRF Health & Bracket |
| Gemphire Therapeutics | , | Acquired via Reverse Merger by NeuroBio, Dec 2019 |
| Fosun Pharma | Tokyo, Japan | Small molecules, diagnostics, traditional |
| , | Acquired by Bio-Rad, Jun 2025, up to $275M | |
| Sinorda Biomedicine | Shanghai, China | Drugs for Digestive Indications, Small Molecules, Cell Therapy, Oncolytic Virus, Antibodies |
| Jubilant Therapeutics | Yardley, PA | Small Molecules |
| , | Website down Sep 2025 - Feb 2026 | |
| Marksans Pharma | , | Website down Jul 2023 - Dec 2023; Separated from Glenmark Pharmaceuticals, Mar 2003 |
| RHEACELL | Heidelberg, Germany | Clinical biopharm company manufacturing cell therapies |
| NantKwest | , | Merged into ImmunityBio, Apr 2021 |
| Abgenix | , | Bought by Amgen 2006 |
| Vivonics | Bedford, MA | Intracranial Pressure and Assessment Screening System |
| Integral Molecular | Philadelphia, PA | Antibody Drug Discovery |
| Cognosci | , | CEO has another job, doesn't seem serious |
| Avestin | Ottawa, ON | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| GenePred | , | Renamed Bilhi Genetics, Mar 2018 |
| Ermium Therapeutics | , | Website down Aug 2024 - Mar 2025 |
| , | Shut down Mar 2026 | |
| Wigen Biomedicine | Shanghai, China | Small Molecules for Tumors |
| Medtronic | Shoreview, MN | Medical Devices |
| ClinGroup | Baabda, Lebanon | Clinical Research |
| Tandem Laboratories | , | Bought by LabCorp, 2008 |
| Bracco | Monroe Township, NJ | Imaging |
| JABio | , | Shut Down May 2021 |
| Lightpoint Medical | , | Acquired by Telix, Nov 2023 |
| Advanced Clinical | Amsterdam, Netherlands | Clinical Research Organization |
| Amicus Therapeutics | Marlow , UK | Small Molecules |
| Trilations | Melbourne, Australia | Strategic Consulting |
| Schein Pharmaceutical | , | Acquired by Watson Pharmaceuticals, Aug 2000, $674M |
| Acrongenomics | , | No info since 2013, seems gone |
| , | Acquired by Alembic Pharmaceuticals, Jul 2025 | |
| Troikaa Pharmaceuticals | Thol, India | Medical Devices |
| Priavoid | Düsseldorf, Germany | All-d-peptides |
| Forward Pharma | , | Licensed all IP permanently to Biogen, Feb 2017 |
| Xylo | Boulder, CO | Psychedelics |
| Legacy Pharmaceuticals | , | Website down Dec 2020 - May 2021 |
| BioIntervene | , | Website down Nov 2023 - Mar 2024 |
| , | No news 2020 - Apr 2026 | |
| Sylics | , | Acquired by Innoser, Jan 2023 |
| C3i Center | Montréal, QC | CDMO providing manufacturing Cell & gene therapy services and testing services from process development to commercial |
| Lys Therapeutics | Lyon, France | BBB-crossing Monoclonal Antibody |
| Dimension Therapeutics | , | Bought by Ultragenyx, Nov 2017 |
| Uniquity Bio | San Diego, CA | Monoclonal Antibody |
| Bio Soft Research | Hyderabad, India | Therapeutic & Data Intelligence CRO |
| Mirror Pharmaceuticals | , | Re-branded as Ingenus Pharmaceuticals |
| Applied Biosystems | , | Bought by Thermo Fisher, Jun 2008, $6.7B |
| California Peptide Research | , | Acquired by Echelon Biosciences, Apr 2014 |
| , | Renamed THX Pharma, Sep 2025 | |
| AuraSense Therapeutics | , | Renamed Exicure |
| Ikano Therapeutics | , | Gone |
| Sintaho Pharmaceutical | Chongqing , China | API Manufacturing, ADC CDMO |
| Sekisui Diagnostics | Darmstadt, Germany | Diagnostics |
| Liberate Medical | Crestwood, KY | Respiratory electrical muscle stimulator |
| Premier Biomedical | , | Pivoted out of life science |
| Pace | St. Rose, LA | Analytical Testing, CDMO |
| AlphaMab Oncology | Suzhou, China | Biologics |
| Extruded Pharmaceutical | , | Renamed CRISM Therapeutics, Jul 2024 |
| Transdermal Technologies | , | Website Gone |
| Artugen Therapeutics | , | Renamed Adiso Therapeutics, Mar 2022 |
| , | Renamed FocalOne, Feb 2026 | |
| Sinotau Pharmaceutical | , | Website down May 2024 - Dec 2024 |
| Bethyl Laboratories | , | Acquired by Fortis Life Sciences, Mar 2021 |
| RxDataScience | , | Acquired by Syneos Health, Oct 2021 |
| Cyrenaic Pharmaceuticals | , | Merged with Sonkei Pharmaceuticals in 2013 to form Minerva Biotechnologies. Moved from NJ to Waltham, MA 2014 |
| AbbVie | Campoverde di Aprilia, Italy | Small Molecules |
| Analytical Lab Group | , | Acquired by Element, now Element Life Sciences |
| Carlina Technologies | , | Website down Dec 2020 - Feb 2021 |
| APCRA | , | Shut down 2020 |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Advanced Analytical Technologies | , | Acquired by Agilent, Mar 2018 |
| Neurokos | , | Gone. No info |
| Affinity Bio | , | Renamed MyriO Tx |
| Barc Lab | , | Renamed Cerba Research |
| Handok | Seoul, Korea | Small Molecules, Biologics, Devices |
| Tympanogen | Richmond, VA | Hydrogel-based devices for ear, nose, and throat applications |
| MicroPort | Clamart, France | Medical Devices |
| Raptamer Discovery Group | , | Fannin company, seems gone Aug 2024; fka AM Biotech |
| Balboa Biosciences | , | Gone 2010 |
| Batavia Biosciences | Leiden, Netherlands | Early Stage Product Development Services |
| Immune Response BioPharma | , | Website down Apr 2022 - Jul 2022 |
| Pace | Asheville, NC | Analytical Testing, CDMO |
| Alliant Diagnostics | , | Renamed Navicus, Mar 2008 |
| Symbiotix Biotherapies | , | Shut down Dec 2021 |
| Deseret Labs | St. George, UT | Pharmaceutical Contract Manufacturing |
| amcure | , | Liquidated Sep 2024 |
| VerAvanti | Bothell, WA | Imaging Technology to Help Uncover Hidden Intravascular Risks |
| Healium Medical | Yokneam, Israel | Ultrasound Ablation |
| H&S Technical Services | , | Acquired by Nipro, 2020 |
| RegeneMed | , | No longer active in CA as of 2014 |
| Ascend Advanced Therapies | Cheshire, UK | Gene Therapy CDMO |
| CJ HealthCare | , | Renamed InnoN, Apr 2020 |
| PRA International | , | Now PRA Health Sciences |
| GlycoBac | Laramie, WY | Improved baculovirus / insect cell expression platform tools |
| Alpine Biosciences | , | Acquired by Oncothyreon Aug 2014, $27M in stock |
| Chrysalis | Waltham, MA | GMP Space |
| CogENT Therapeutics | , | Main asset acquired by Intellus Medical, Jun 2016 |
| LifeSensors | , | Website hijacked Feb 2025 |
| AntriaBio | , | Changed name to Rezolute, Dec 2017 |
| WEX Pharmaceuticals | , | Merged with Virios Therapeutics to become Dogwood Therapeutics, Oct 2024 |
| Dynex Technologies | West Sussex, UK | Microplate Readers, Technology |
| Quantimetrix | Redondo Beach, CA | Urinalysis Dipstick |
| myoscience | , | Renamed iovera |
| Sunflower Therapeutics | Medford, MA | Efficient biologics drug development platform |
| BrainStorm Cell Therapeutics | New York, NY | Autologous, adult stem cell therapy technology |
| Vyaire Medical | , | Website down Jun 2025; Filed Chapter 11 Bankruptcy, Jun 2024; Spun out of CareFusion Oct 2016 |
| Diatherix Laboratories | , | Acquired by eurofins, $50M |
| rhealth | Bedford, MA | Diagnostics |
| PQ Bypass | , | Acquired by Thermo Fisher, Apr 2021, $17.4B |
| Epizyme | , | Website down Dec 2022 - Apr 2023; Acquired by Ispen, Aug 2022, $247M |
| Gismo Therapeutics | , | No news 2017 - Jul 2024 |
| Elcelyx Therapeutics | , | Website expired/down Aug 2019 - Oct 2019 after five funding rounds |
| Siragen Pharmaceuticals | , | Website down Sep 2021 - Feb 2022; Same location/personnel as Neurogeneration |
| Loop Medical | Lausanne, Switzerland | Blood Collection Device |
| , | Acquired by eurofins, Aug 2019; Bought by OriGene Aug 2010 | |
| Corner Therapeutics | Watertown, MA | Dendritic cell hyperactivation (hDC) platform, inflammasomes |
| Tyler Pharmaceuticals | , | Website down Apr 2023 - Sep 2023 |
| Ossur | Irvine, CA | Orthopedic Devices |
| Belyntic | Berlin, Germany | Immunotherapies |
| Katama Pharmaceuticals | , | Founded 2012, no additional business filing as of Dec 2019 |
| CardioProlific | , | Bought by Philips, Jun 2017 |
| BlueRock Therapeutics | New York, NY | Stem Cell Therapies |
| Blank Bio | San Francisco, CA | RNA intelligence for precision oncology |
| Memry | , | Acquired by Resonetics, Oct 2023 |
| UniteLabs | , | Shut Down |
| Advanced Accelerator Applications | , | Bought by Novartis, Nov 2017, $3.9B |
| Northern Lipids | , | Renamed Transferra |
| Creo Medical | Chepstow, UK | Therapeutic Endoscopy |
| Verity Pharmaceuticals | Ewing, NJ | Specialty genitourinary therapies |
| , | Website down Aug 2025 - Jan 2026; Acquired by NAMSA | |
| Oval Medical Technologies | , | Rolled into parent, SMC |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| Cook Medical | Bloomington, IN | Medical Devices, Contract Manufacturing |
| NeuroSense Therapeutics | Herzliya, Israel | Ciprofloxacin and Celecoxib combo |
| Wockhardt | Ankleshwar, India | Generics, Contract Manufacturing |
| Prognosys Bioscience | , | 10 years in stealth mode |
| American Biooptics | , | Renamed Avivo BioOptics |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Onset Dermatologics | , | Acquired by Valeant Feb 2014 |
| Pharmasyntez | Irkutsk, Russia | Small Molecules |
| Amanta Healthcare | Ahmedabad , India | Sterile Liquid Parenterals |
| AGCT GENOMICS | , | Website gone Mar 2022 |
| DFW Clinical Research | , | now part of KeyPoint Clinical Research |
| ReNetX Bio | , | Website down Nov 2024 - May 2025; fka Axerion Therapeutics |
| NeurAxon | , | No updates since 2008 |
| EOC Pharma | Shanghai, China | In licensing for Chinese market |
| ManRos Therapeutics | , | Merged into Perha Pharma |
| |
Hyderabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cellero | , | Acquired by Charles River, Aug 2020, $38M; fka Astarte Biologics; Merged with Key Biologics, Aug 2018 |
| |
Bad Aibling, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Xspire Pharma | , | Renamed Key Therapeutics, Sep 2024 |
| Microtissues | , | Not a registered business in MA, Feb 2024 despite being 15 years old; Residential Address, Feb 2024 |
| ZebraSci | Temecula, CA | Contract Manufacturing, Development - Drugs & Devices |
| TME Pharma | Berlin, Germany | L-aptamers |
| PharPoint Research | Wilmington, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Fosun Pharma | New York, NY | Small molecules, diagnostics, traditional |
| InnVentis | , | Website down Mar 2025 - Aug 2025; CEO does not listed on extensive LI profile |
| Vaxart | South SF, CA | Oral Vaccines |
| Cell Constructs | , | Website down Jul 2021 - Dec 2021 |
| Aspect Biosystems | Vancouver, BC | 3D bioprinting |
| Nucleus Network | Herston, Australia | Clinical Research |
| Kinathera | , | Website down Feb 2025 - Jul 2025; fka Balmes Transplantation |
| BrickBio | Waltham, MA | Protein Engineering, Antibody Conjugation, Services |
| Manufacturing & Research Inc | , | Renamed Xeridiem, 2011 |
| Millipore | Bedford, MA | Purification, Analytic Biologics, Discovery |
| Azafaros | DC Naarden, Netherlands | Small Molecules |
| Onux medical | , | Acquired by Bard, Jul 2004 |
| Gnomegen | , | Website Gone, not sure what's up with the company. Legally active as of Oct 2017, but presumed inactive |
| Medicrea | , | Acquired by Medtronic, Nov 2020 |
| Getinge | Getinge, Sweden | Medical Technology |
| Aziyo Biologics | , | Renamed Elutia, Sep 2023 |
| CelLBxHealth | Guildford, UK | Liquid Biopsy |
| Good Start Genetics | , | Acquired by Invitae, Aug 2017 |
| Symphogen | , | Acquired by Servier, Jun 2020 |
| Hybritech | , | Bought by Lilly, 1986, $400M+ |
| Accium BioSciences | , | Shut down Oct 2024 |
| Iceni Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka BigDNA |
| Gene Therapy Research Institute (GTRI) | , | Renamed Onodera, Mar 2025 |
| Medimetriks Pharmaceuticals | West Fairfield, NJ | Specialty Pharma - Derm & Podiatry |
| |
Feldkirchen, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| BioClin Therapeutics | , | Renamed Rainier Therapeutics, Nov 2018 |
| Lucy Scientific Discovery | , | Delisted Shell Company Mar 2025; Website down Oct 2024 - Mar 2025 |
| MEDISPECTRA | , | Gone 2002 |
| BlueRock Therapeutics | Berlin, Germany | Stem Cell Therapies |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| KemPharm | , | Renamed Zevra Therapeutics, Feb 2023 |
| Metuchen Pharmaceuticals | , | Merged with Neurotrope Biosciences to become Patros Pharmaceuticals |
| Nyxoah | Mont-Saint-Guibert, Belgium | Implantable Sleep Aide Neurostimulation Device |
| eXIthera Pharmaceuticals | , | Assets acquired by Cadrenal Therapeutics, Sep 2025; No business filings Jan 2022 - Aug 2024 |
| Hyalose | , | Website down Jun 2021 - Oct 2021 |
| Sixal | , | SBIR, Presumed defunct |
| GandTex | , | Assets Acquired by SmooFi, Oct 2016 |
| Lobesity | , | Assets acquired by 9 Meters Biopharma, Jul 2021, $5M + $45M milestones |
| Resprotect | , | No update since 2012 as of 2020 |
| Iron Horse Therapeutics | , | Founded 2015, no website Aug 2021 |
| Ferrosan | Szczecin, Poland | Surgical hemostatic products and medical devices |
| Sevion Therapeutics | , | Acquired Eloxx Pharmaceuticals, Dec 2017, took name |
| AtheroGenics | , | Assets Sold Off 2009 |
| Molecular Throughput | , | Rebranded as mtibio |
| |
Boston, MA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| , | Acquired by Precision CellSystems, Nov 2025 | |
| Amnestix | , | Acquired by SYGNIS, Jun 2008, $6M |
| Ipsen | Barcelona, Spain | Small Molecules, Biologics |
| Neurovance | , | Acquired by Otsuka Pharmaceuticals, Mar 2017, $100M + $150M milestones; Euthymics spinout |
| Onspira Therapeutics | , | Acquired by Altavant Sciences, Jan 2020 |
| Radius Health | Boston, MA | Small Molecules, Biologics |
| Pfizer | Toluca, Mexico | Small Molecules, Biologics, Vaccines |
| Intersect Diagnostics | , | Website down Feb 2025 - Jun 2025 |
| , | Website down Mar 2026; No news 2021 - Aug 2025 | |
| Asymchem | Morrisville, NC | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Core Biogenesis | Paris, France | Plant-based Recombinant Protein Production |
| Coda Biotherapeutics | , | Shut down Oct 2022 |
| DNA Polymerase Technology | St. Louis, MO | Genetically-modified Enzymes |
| Qualio | San Francisco, CA | Life Sciences Quality Management System |
| Acist Medical Systems | Eden Prairie, MN | Interventional and diagnostic technology |
| Biotheus | , | Acquired by BioNTech, Feb 2025 |
| Pumpinheart | Dublin, Ireland | Transcatheter, implantable diastolic heart pump system |
| , | Website down, Dec 2025 - Jun 2026 | |
| Marcadia Biotech | , | Acquired by Roche Dec 2010 |
| Synvista Therapeutics | , | Terminated clinical studies to focus on diagnostics in 2009, but no other info |
| Origin Biosciences | , | Website down May 2022 - Jul 2022; Sold product to Sentynl Therapeutics, Mar 2022 |
| Antiverse | Cardiff, UK | Computational antibody drug discovery platform |
| WEP Clinical | Morrisville, NC | Clinical Research Organization |
| Galileo Research | , | No news since 2012, presumed gone |
| Novocure | Haifa, Israel | Tumor Treating Fields |
| Advanced Stent Technologies | , | Acquired by Boston Scientific Dec 2004 |
| Novastage Pharmaceuticals | Shenzhen, China | Transdermal patch and oral film drug products |
| , | Renamed Virchow | |
| Alba Therapeutics | , | All assets licensed to Innovate Biopharmaceuticals |
| NanoBlate | , | Merged with BioElectroMed & ThelioPulse to become Pulse Biomedical, Nov 2014 |
| Natco Pharma | Vijayapuri North, India | Generics, APIs, Contract Manufacturing |
| Argon Medical Devices | Wheeling, IL | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Nexgen Biosciences | , | Website down Dec 2019 - Mar 2020 |
| WiseGene | , | Website gone jan 2020 |
| Pace | Ormond Beach, FL | Analytical Testing, CDMO |
| Allelix | , | Merged with NPS |
| Fitzpatrick Company | Waterloo, ON | Solids processing equipment |
| Transpire Bio | Weston, FL | Inhalable Therapies |
| Bone Bank Allografts | San Antonio, TX | Tissues |
| Sangart | , | Ostensibly Gone after failed trial, Nov 2013 |
| Intellia Therapeutics | Cambridge, MA | Therapeutic gene editing (CRISPR) |
| Merck | Rahway, NJ | Small Molecules, Vaccines, Biologics |
| Calmune | , | Liquidated |
| Jordi labs | Mansfield, MA | Analytical chemistry testing services |
| Coherus BioSciences | , | Renamed Coherus Oncology, May 2025 |
| Artu Biologicals | , | Sold by Fornix Biosciences to ALK-Abello |
| Gala Therapeutics | , | Renamed Galvanize Therapeutics, Spr 2022 |
| , | No news 2021 - Sep 2025 | |
| PsychoGenics | Paramus, NJ | Bioinformatics, Target Validation |
| Pharos Dx | , | Gone |
| , | Acquired by Merit Medical, Jun 2023 | |
| Pharma Two B | , | Website down Feb 2025 - May 2025 |
| Oncore Pharma | , | Website gone Oct 2021, not registered business in MA |
| Tokai Pharmaceuticals | , | Merged with OticPharma, May 2017, Changed name to Novus Therapeutics |
| Biedermann Motech | Schaffhausen , Switzerland | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Thermalin | , | Website down Jun 2023 - Dec 2023; fka Themalin Diabetes |
| Heart Repair Technologies | , | |
| |
Regensburg, Germany | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Tempo Bioscience | San Francisco, CA | Stem cell models, biosensor assay services, disease modeling |
| ExcelseBio | , | Part of IntegrityBio |
| Cambrex | Durham, NC | Small Molecules Research, Development & Manufacturing Services |
| Sambi Pharma | Hyderabad , India | Preclinical Contract Research |
| Intelligent MDx | , | Shut down, Feb 2015 |
| Genetix Pharmaceuticals | , | Renamed bluebird bio, Sep 2010 |
| Clinical Genomics | , | Website down Oct 2022 - Mar 2023 |
| Find Therapeutics | Saint-Laurent, QC | GPCR-Targeting Therapeutics |
| Vimela Therapeutics | , | Subsidiary of Alys Pharmaceuticals |
| Incendia Therapeutics | Cambridge, MA | Cancer Barrier Penetrating Therapies |
| Clavis Pharma | , | Changed Name to Aqualis, 2013 |
| BioLegend | San Diego, CA | Cytokines, Reagents, etc. |
| Bionomics | , | Renamed Neuphoria Therapeutics, Dec 2024 |
| Proneurotech | , | Renamed Nura Bio, Apr 2020 |
| , | Website down Oct 2025 - Feb 2026 | |
| PEEL Therapeutics | Salt Lake City, UT | Nature-inspired Cancer Therapies |
| Fresenius Kabi | Aquiraz, Brazil | Contract Manufacturing |
| BIND Biosciences | , | Now BIND Therapeutics |
| Kintai Therapeutics | , | Renamed Senda Biosciences |
| , | Acquired by WuXi AppTec, Mar 2021, $135M | |
| CroiValve | Dublin, Ireland | Minimally invasive solution for severe Tricuspid Regurgitation |
| TetraGenetics | , | Acquired by AbCellera, Sep 2021 |
| PrimeGen US | Santa Ana , CA | Stem Cell Therapy |
| Abcam | Waltham, MA | Antibodies |
| Brain Neurotherapy Bio | , | Merged with AskBio, Dec 2020 |
| Aimmune Therapeutics | , | |
| Compass Biomedical | , | No employees on LI Oct 2022; Not a registered business in MA, Dec 2019 - Oct 2022; fka Arteriocyte |
| Advanz Pharma | Mumbai, India | Specialty Generics |
| EmbarkNeuro | , | Website down Feb 2025 - Jun 2025 |
| Lasergen | , | Acquired by Agilent, Apr 2018, $105M |
| Pharmion | , | Acquired by Celgene 2007 |
| Cygene Labs | , | Gone |
| Pairnomix | , | Merged with Q-State Biosciences, Nov 2018 |
| Aires Pharmaceuticals | , | Acquired by Mast Therapeutics, Apr 2014 |
| Anesta | , | Merged with Cephalon, Oct 2000 |
| NanoAntibiotics | , | Changed name to BioVie, Apr 2016 |
| Voyage Biomedical | , | Website gone Jul 2020 - Mar 2021 |
| Orbis Medicines | Frederiksberg, Denmark | Oral Macrocyclic Drug Delivery |
| Rgene | , | Late business filings Aug 2021 |
| ActoGeniX | , | Acquired by Intrexon, $60M, Feb 2015 |
| George Clinical | , | Renamed Emerald Clinical Trials, Apr 2025 |
| Magnolia Therapeutics | , | Website gone Oct 2019 |
| bioMerieux | Marcy l'Étoile, France | Diagnostics |
| MyeloRx | , | Still registered Jun 2020, but no website update since 2011; co-located with Riptide Bioscience |
| Geneious | Auckland, New Zealand | Bioinformatics Consulting & Design |
| Medical Adhesive Revolution | , | Renamed Adhesys Medical, Feb 2016 |
| Jecure Therapeutics | , | Acquired by Genentech, Nov 2018 |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Soluble Systems | , | Renamed Solsys Medical |
| Asterand | , | Bought by Stemgent, Aug 2012, Some assets sold on to ReproCELL, then company renamed Asterand Bioscience |
| Accumed Systems | , | Dated website, cant find any employees |
| Nirrin Technologies | Billerica, MA | Bioprocessing Analytical Systems |
| Idec | , | Became Biogen Idec after merging with Biogen in 2003 |
| Tr1X | San Diego, CA | Regulatory T cell-based products |
| NeuroBionics | Somerville, MA | Minimally invasive, implantable endovascular neuromodulation devices |
| Affinium Pharmaceuticals | , | Assets acquired by Debiopharm, Feb 2014 |
| Arcxis Biotechnologies | , | IP and most assets sold to Fluidigm 2010 |
| Acotec | Beijing, China | Drug-coated balloons for treating vascular diseases |
| Velox Therapeutics | , | Renamed Abata Therapeutics, Nov 2021 |
| Unither Pharmaceuticals | Paris, France | CDMO |
| T-Cure Bioscience | Irvine, CA | TCR Therapy |
| Melema Pharma | , | No news 2017 - Feb 2024 |
| Endurance Biotech | , | Renamed Bonti, Aug 2015 |
| , | Seems inactive Jan 2026 | |
| Disphar International | , | Renamed Esperante Development, May 2023 |
| Rizana Therapeutics | , | Shut down Jul 2021 |
| Lederle Labs | , | Bought by Wyeth 1994 |
| SmartCardia | Lausanne, Switzerland | AI-powered 7-lead ECG patch and cloud platform |
| Self-screen | Amsterdam, Netherlands | Cervical Cancer Diagnostic |
| Congruence Therapeutics | Montréal, QC | Computational platform for small molecule discovery targeting protein misfolding diseases |
| , | Website down Nov 2025 - Apr 2026 | |
| Genolution | Seoul, Korea | DNA Extraction Technology, Kits |
| PledPharma | , | Renamed Egetis Therapeutics, Dec 2020 |
| PharmAthene | , | Merged with Altimmune, Jan 2017 |
| Pacira Biosciences | San Diego, CA | Drug Delivery |
| Abaxis | , | Bought by Zoetis, Jul 2018 |
| Cellular Research | , | Acquired by BD, Aug 2015 |
| Swissfillon | , | Acquired by ten23, Oct 2021 |
| Cellaion | , | Website down Feb 2025 - Jul 2025; fka Promethera Biosciences |
| Asante Solutions | , | Assets acquired by Bigfoot Biomedical, May 2015 |
| Abera Bioscience | Uppsala, Sweden | Vaccine platform that can be decorated with multiple antigens |
| |
Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| 1859, Inc. | , | Shut down Jul 2023 |
| Medovex | , | Renamed H-Cyte, Jul 2019 |
| Kite Pharma | Hoofddorp, Netherlands | Engineered Autologous T Cell Therapy, CAR-T |
| Nihon Kohden | Saitama, Japan | Medical Electronic Equipment |
| Sterling Industries | Kalamazoo, MI | Medical Device Contract Manufacturing & Development |
| Mereo BioPharma | London, UK | Acquisition & rapid development of drugs |
| Immunovaccine | , | Rebranded IMV, 2018 |
| Sagent Pharmaceuticals | Schaumburg, IL | Injectable Small Molecules |
| Modra Pharmaceuticals | Amsterdam, Netherlands | Oral chemotherapies |
| Catalytica Pharmaceuticals | , | Acquired by DSM |
| Eboo Pharmaceuticals | , | Renamed Dina Pharmaceuticals, 2016 |
| ProTrials Research | Los Gatos, CA | Clinical Research |
| Immunotope | , | Created 2003, no updates since 2011 as of Dec 2019 |
| Relypsa | , | Bought by Galenica, Jul 2016, $1.5B, became part of Vifor |
| Acuvax | , | Pivoted to investments, 2014 |
| Symbiotic Health | , | CEO moved on, still on website four years later |
| aceRNA Technology | Tokyo, Japan | RNA Switch Technology |
| Alpha-9 Oncology | Boston, MA | Radiopharmaceuticals |
| Marea Therapeutics | South SF, CA | Treatments for Cardiometabolic Diseases |
| ACD Pharma | Leknes, Norway | Bacteriophages |
| Pheon Therapeutics | Harpenden, UK | Antibody-drug Conjugates |
| Sangamo Biosciences | , | Renamed Sangamo Therapeutics, Jan 2017 |
| Zylacta | , | No news 2015 - Oct 2024 |
| Kashiv BioSciences | Piscataway, NJ | Biosimilars |
| TCA Cellular Therapy | , | Website Gone, failed to file annual report with LA |
| Sitryx | Oxford, UK | Immunometabolic therapies |
| Lonza | Cohasset, MN | Contract Manufacturing, Reagents, Stem Cells, Services |
| , | Acquired by Instem, Jul 2025 | |
| Translational Drug Development (TD2) | , | Renamed TD2 Precision Oncology |
| Cytocom | , | Renamed Statera Biopharma, Sep 2021 |
| NoyMed | Glendale, CA | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Dynacare | , | Bought by LabCorp 2002 |
| Cytonet | , | Key Assets acquired by Prometera Biosciences, Apr 2016 |
| icometrix | Boston, MA | Imaging AI |
| MedShape | , | Acquired by DJO, Apr 2021 |
| , | Shut down Oct 2025 | |
| Dornier MedTech | Rome, Italy | Urology Devices |
| Oticon | Smørum, Denmark | Hearing Aids |
| Tonix Pharmaceuticals | Chatham, NJ | CNS Disorders |
| FerGene | , | Website Gone Jan 2023 - Feb 2023; Ferring/Blackstone JV |
| Five Star Products | , | Liquidated |
| Aytu BioPharma | Denver, CO | Small Molecule, Diagnostics |
| Redwood Bioscience | , | Acquired by Catalent, Oct 2014 |
| Cambridge Major Labs | , | Merged with AAIPharma Services, Renamed Alcami |
| Oribase Pharma | , | Website down, owners/founders have other jobs |
| Cambrian Genomics | , | Shut down Dec 2017 |
| Sentiss | Gurugram, India | Ophthalmic, respiratory, otolaryngologic, and wound care products |
| LuSeed Vascular | Petah Tikva, Israel | Minimally invasive device for treating both Bifurcation and Sidewall brain aneurysms |
| Aplagen | , | No activity since 2008 |
| Coferon | , | Renamed BlinkBio |
| Anulex Technologies | , | Closed 2014 |
| Mercury Medical | Clearwater , FL | Airway management, emergency, respiratory, neonatal devices |
| Qualitis | , | Acquired by Optima Pharm, Jun 2022 |
| Kimer Med | Nelson , New Zealand | Antivirals |
| Septodont | Cambridge, ON | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| G3 Pharmaceuticals | , | Website down Dec 2024 - May 2025; Looking to acquire products? |
| Lancaster Laboratories | , | Bought by eurofins, Apr 2011, $200M |
| BioPharma Services | Creve Coeur, MO | Clinical Trial Services |
| Intelliseq | Kraków, Poland | Genome Informatics |
| Quince Therapeutics | South SF, CA | Alzheimer's treatment |
| Neuraltus Pharmaceuticals | , | Product failed in clinic, Apr 2019; Website gone Apr 2019 |
| Hepalink | Shenzhen, China | Heparin API |
| LinkChem | Shanghai, China | CDMO |
| Roche | Shanghai, China | Small Molecules & Diagnostics |
| Absolute Antibody | Cleveland, UK | Antibody expression and engineering services |
| Scispot | Kitchener, ON | AI-powered platform enabling biotech labs to digitize and scale efficiently with solutions like ELN, LIMS, SDMS and automated analytics |
| MJ Geneworks | , | Acquired by Bio-Rad, Aug 2004, $32M |
| Eledon Pharmaceuticals | Irvine, CA | ENT Treatments |
| Vernacare | Blackwood, UK | Surgical Devices |
| EOC Pharma | Beijing, China | In licensing for Chinese market |
| 2bind | Regensburg, Germany | Biophysical analysis contract research |
| Primmbiotech | , | Website down Apr 2021 - Sep 2021 |
| Vertanical | Gräfelfing, Germany | Cannabinoid-based medicinal product |
| Vividion Therapeutics | San Diego, CA | Proprietary Screening |
| Alna-Biscience | Hamburg, Germany | Life Science Products, Cell Culture Media |
| Hill-Rom | , | Rebranded as Hillrom, May 2019 |
| Ingenuity Systems | , | Bought by Qiagen, renamed Ingenuity, folded into Qiagen |
| Janvier Labs | Pays de Loire, France | Rodent Models |
| , | Part of Normec | |
| Isomorphic Labs | London, UK | AI Drug Discovery |
| Dipharma | Caronno Pertusella, Italy | APIs, Generics |
| VisionCare | , | Renamed Samsara Vision, Nov 2020 |
| Engage Surgical | , | Acquired by Smith + Nephew, Jan 2022, $135M |
| StemImmune | , | Renamed Calidi Biotherapeutics, May 2018 |
| nRichDX | Irvine, CA | cfDNA Diagnostics |
| Nexxt Spine | Noblesville, IN | Spinal Implant Devices |
| AGS Therapeutics | Paris, France | Microalgal extracellular vesicles |
| Stealth Biologics | , | Acquired by Occulo, Apr 2018 |
| , | Renamed Daisy Genomics, Dec 2025 | |
| Biograph 55 | , | No website Dec 2021 - Jul 2025 |
| BioAxoneTherapeutic | , | Founded 2000, all assets acquired by BioAxone Biosciences |
| Maplehurst Genetics International | , | Website gone |
| Tiltan Pharma | , | Phase 2 should have been done early 2017 - no news of anything since 2016 as of 2020 |
| Pelago Bioscience | Solna, Sweden | Assay Services |
| DiaCarta | Hayward, CA | Molecular Diagnostics Tests |
| Helsinn | Dublin, Ireland | Small Molecules |
| Altus Biologics | , | Vertex Subsidiary |
| Roche | Pleasanton, CA | Diagnostics |
| Upsher-Smith | Plymouth, MN | Small Molecules, Generics |
| Revive Solutions | , | Renamed Avive Solutions, Sep 2019 |
| CBH ClinTrials | , | now CenExelCBH |
| Alpha Biologics | , | Assets seized by Malaysian bank, Sep 2014. Subsidiary of ViroPro |
| , | Website down Oct 2025 - Feb 2026 | |
| AlgoNomics | , | Acquired by Lonza, Nov 2009 |
| LizarBio Therapeutics | , | Website down Jul 2023 - Dec 2023 |
| , | Website down Jan 2026 - Mar 2026 | |
| Rise Therapeutics | Rockville, MD | Orally Bioavailable Protein Therapeutics |
| ARV Technologies | , | Renamed Pinion Immunotherapeutics, Jan 2025 |
| US Endoscopy | , | Acquired by Steris, Jul 2012 |
| Synergen | , | Bought by Amgen 1994 |
| Proteostasis Therapeutics | , | Reverse merged by Yumanity, Dec 2020 |
| Oncolines | Oss, Netherlands | Biomarker identification in cancer cell profiles |
| Anergis | , | Liquidating, Jan 2021 |
| SFS | Madrid, Spain | Clinical Research Organization |
| Suvoda | Bucharest, Romania | Clinical Trial Software |
| SomaServe | , | Renamed ViaNautis Bio |
| Aloka | , | Acquired by Hitachi Medical, Jun 2011 |
| Eli Lilly | Kinsale, Ireland | Small Molecules, Biologics |
| Éclat Pharmaceuticals | , | Joined with Flamel & FSC Pediatrics to be rebranded as Avadel Pharmaceuticals Jan 2017; Acquired by Flamel Technologies Mar 2012 |
| Alms Therapeutics | , | Gone Jul 2022 |
| Alkaloid AD Skopje | Skopje, North Macedonia | Large scale pharma and chemicals manufacturing/botanicals and cosmetics processing |
| Noul | Yongin, Korea | Decentralized Diagnostic Platform |
| Appasamy Associates | Chennai, India | Ophthalmic Equipment, Micro Surgical Instruments, Intraocular lenses |
| Juniper Biologics | Singapore , Singapore | Small Molecules, Cell Therapy, Gene Therapy |
| Revvity | Boston, MA | Diagnostics, Services |
| Harbinger Health | Cambridge, MA | Cancer Diagnostics |
| SilcsBio | Baltimore, MD | Drug design simulation software |
| CB Therapeutics | Carlsbad, CA | Synthesis of Cannabinoids from Sugar |
| Targetgene Biotechnologies | Rehovot, Israel | Gene Edited, immune cell based therapies |
| Suvoda | Barcelona, Spain | Clinical Trial Software |
| MetVital | , | Business filings late Feb 2023; No news 2020 - Aug 2024 |
| EyeTel Imaging | , | Gone Jul 2015 |
| Charles River Laboratories | Tranent, UK | Research Animal Models and Preclinical Research |
| Staburo | Munich, Germany | Clinical Services |
| Dyax | , | Bought by Shire, Jan 2016, $5.9B |
| Statsols | , | Aquired by Dotmatics, 2022; aka Statistical Solutions |
| UBC | Uxbridge, UK | Biopharmaceutical Consulting & Services |
| The MT Group | Los Angeles, CA | Biospecimen Collection |
| Cell>Point | , | Cant find any confirmation they are active |
| Heidelberg Immunotherapeutics | , | Website under construction Feb 2020 - Mar 2021 |
| Hexagon Pharma | Stockholm, Sweden | Manufacturing Technology |
| Waratah Pharmaceuticals | , | Gone 2007 |
| Matrix-Bio | , | Website down Apr 2022 - Aug 2022; Seems virtual; Residential address |
| Sequani Medical | Hereford, UK | Clinical Trial Support Services |
| A&M Biomedical | , | Website down Feb 2023 - Jul 2023 |
| Ascend Advanced Therapies | Alachua, FL | Gene Therapy CDMO |
| Seahorse Bioscience | , | Acquired by Agilent, Nov 2015 |
| Sun Pharmaceuticals | Mumbai , India | Generic Small Molecules, APIs |
| Sanctum Therapeutics | , | Acquired by Adnexus, Nov 2024 |
| Lyell Immunopharma | Seattle, WA | Curative cell-based immunotherapies |
| Beckman Coulter Diagnostics | Brea, CA | Diagnostics, Equipment |
| Kaydence Pharma | , | Website down Sep 2022 - Feb 2023; say they are in NJ., but actually in Oslo |
| Kantum Pharma | , | Website down Dec 2022 - Apr 2023 |
| Vaxin | , | Changed name to Altimmune Sep 2015 |
| Pledge Therapeutics | Canton, MA | Antivirals, Antiinfectives, Immuno-Oncology |
| IDbyDNA | , | Acquired by Illumina, Jun 2022 |
| DIGNITANA | Dallas, TX | Scalp Cooling Device to Minimize Cancer Treatment Hair Loss |
| Catalent | Morrisville, NC | Analytical Services, Inhalation Product Development |
| InDex Pharmaceuticals | , | Acquired by Investors, Jun 2024 |
| LENSAR | Orlando, FL | Cataract Laser |
| Summit Medical Group | Gloucestershire, UK | Medical devices and surgical products |
| Voltarra Pharmaceuticals | , | Changed name to Levolta Pharmaceuticals |
| Spherotech | Lake Forest, IL | Microparticles for Diagnostics |
| Norgine | Amsterdam, Netherlands | Specialty Pharma |
| Iomai | , | Bought by Intercell 2008 |
| Pinpoint Therapeutics | , | No News Apr 2020 - Jan 2025 |
| MyX Therapeutics | , | Website down May 2021 - Sep 2021 |
| Epiomed Therapeutics | , | Gone |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| DDi | London, UK | Clinical Software |
| Flexios | , | No website, everyone has new jobs Dec 2019 |
| Hercules Pharmaceuticals | , | Website down Sep 2024 - Feb 2025 |
| Origene | Herford, Germany | Human cDNA Library, Monoclonal Antibodies |
| Actient Pharmaceuticals | , | Acquired by Auxilium Pharmaceuticals, Apr 2013 |
| Consensus Orthopedics | , | Renamed Shalby Advanced Technologies, Jan 2023 |
| Grove Biopharma | Chicago, IL | Therapeutic targeting of protein-protein interactions |
| Actis Biologics | , | Gone |
| PamDx | s-Hertogenbosch, Netherlands | Kinase activity profiling services, nuclear receptor assays, biomarker discovery |
| , | Website down Jan 2026 - May 2026 | |
| Hydra Biosciences | , | Website gone Mar 2019 |
| MasterControl | Salt Lake City, UT | Quality Management Systems |
| SkinAxis | , | Website weird Dec 2023 - Jul 2024 |
| Securus Medical | , | Bought by Boston Scientific, Apr 2018, $40M |
| Greiner Bio-One North America | Monroe, NC | Cell Culture Products |
| ArQule | , | Bought by Merck, Jan 2020, $2.7B |
| Novo Nordisk | Bloomington, IN | Diabetes, obesity, liver disease and other therapeutic areas |
| |
Philadelphia, PA | KCAS Bio is a top CRO for bioanalytical and biomarker services globally. |
| Madeira Therapeutics | , | Gone. No info |
| Hutchmed | Hong Kong, China | Oral drugs |
| Adragos Pharma | Munich, Germany | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| |
Sarajevo, Bosnia & Herzogovina | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Durata Therapeutics | , | Acquired by Actavis, Nov 2014, $675M |
| Thar Pharmaceuticals | , | Acquired by Grünenthal, Nov 2016 |
| Ennov | Paris, France | Software Solutions |
| DrugCendR | , | Renamed CEND Therapeutics, Jun 2020 |
| Hoth Therapeutics | New York, NY | Small Molecules |
| Selkirk Pharma | Spokane, WA | Annex 1 compliant clinical and commercial fill/finish CMO |
| KEW Group | , | Website down Nov 2024 - Apr 2025 |
| ImaRx | , | Assets acquired by newly formed Cerevast Therapeutics in 2009 |
| AXCENTUA Pharmaceuticals | , | No updates since 2014 |
| Arthrocare | , | Acquired by Smith & Nephew, May 2014 |
| KCR | , | Acquired by ICON plc, Feb 2024; fka Kiecana Clinical Research |
| Vaximm | Basel, Switzerland | Attenuated bacterial therapy |
| Bioarray Genetics | , | Founder left, website gone Oct 2019 |
| Dexcel Pharma | Or Akiva, Israel | Generics |
| BioVolutions | , | Gone |
| DiagnoCure | , | Liquidated, Apr 2016 |
| |
Rensselaer, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Minakem | Mont-Saint-Guibert, Belgium | API Manufacturing |
| Cosman Medical | , | Bought by Boston Scientific, Jul 2016 |
| Precisio Biotix Therapeutics | Dover, DE | Biological Antibacterials |
| Eurosequence | , | Website gone Jan 2020 |
| Geltex Pharmaceuticals | , | Bought by Genzyme |
| Frontage | Shanghai, China | Contract Research & Development, Clinical Services, CMC Services |
| DMS Imaging | Gallargues-le-Montueux, France | Imaging |
| Phage Biotechnology Corp | , | Renamed Phage Pharmaceuticals |
| Catalyst Pharmaceuticals | Coral Gables, FL | Small Molecules for Addiction Treatment |
| BioMarin Pharmaceutical | London, UK | Biologics |
| Galleon Pharmaceuticals | , | Website Gone, Mar 2017, site taken over by snoring info |
| GSK | Singapore, Singapore | Small Molecules, Vaccines, Biologics |
| Calviri | Phoenix, AZ | Cancer Diagnostics & Therapeutics |
| AventaCell BioMedical | , | LI page gone Nov 2023; No news Apr 2022 - Feb 2025 |
| Strohl Medical Technologies | , | Employees all gone, including founder |
| Clario | Philadelphia, PA | Clinical Services |
| Carrington Labs | , | Changed Name to DelSite |
| Biocytogen | Waltham, MA | CRISPR genome editing, preclinical services |
| Formex | , | Merged into BioDuro, Nov 2015 |
| Roche | Buonas, Switzerland | Diagnostics |
| Bioavlee | , | Website Down May 2024 - Nov 2024 |
| Capstan Medical | Santa Cruz, CA | Heart Valve Replacement |
| , | Website down Jan 2026 - Apr 2026 | |
| Orthologic | , | Now Capstone Therapeutics |
| Apotheca Therapeutics | , | Renamed Actuate Therapeutics, Feb 2017? |
| Olon USA | Concord, OH | Contract Research |
| Elorac Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Relion | , | Shut down 2015? |
| Batu Biologics | , | Gone 2019? |
| Western Oncolytics | , | Website down Jun 2021 - Oct 2021 |
| LGC Biosearch Technologies | Lystrup , Denmark | Custom oligonucleotide synthesis |
| Kips Bay Medical | , | Closed 2015 after poor clinical trial results |
| CHF Solutions | , | Renamed Nuwellis, May 2021 |
| |
San Diego, CA | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Tensha Therapeutics | , | Acquired by Roche, Jan 2016, $115M + $420 Milestones |
| LinaTech | Sunnyvale, CA | Cancer treatment device |
| Proteologix | , | Acquired by J&J May 2024, $850M; No website, Feb 2023 - Nov 2023 |
| Nucleai | Chicago, IL | AI-powered Tumor Micro Environment modeling |
| LifeSci Compliance | , | Website gone, Dec 2018 |
| Glamorous AI | , | Acquired by X-Chem, Oct 2021 |
| Sterling Pharma Solutions | Cary, NC | Contract Development & Manufacturing - APIs |
| , | Acquired by HB Fuller, Jul 2023 | |
| Immatics Biotechnologies | Stafford, TX | Personalized T-cell Directed Immunotherapies |
| Vali Nanomedical | , | Gone 2016 |
| TransCode Therapeutics | Newton, MA | RNA Delivery, Small Molecule |
| BeOne Medicines | Ridgefield Park, NJ | Small Molecules, Monoclonal Antibodies |
| Charnwood Discovery | Derbyshire, UK | Chemistry Services |
| Tetra Therapeutics | , | Acquired by Shionogi, May 2020; fka Tetra Discovery Partners |
| Geneyx Genomex | Herzliya, Israel | NGS Data Analysis |
| Sharp | Hamont-Achel, Belgium | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Ixchel Scientific | , | Renamed zPREDICTA |
| Eclipse Therapeutics | , | Bought by Bionomics, Sep 2012, $10M |
| SCHOTT Pharma | Lebanon, PA | Drug containment solutions and delivery systems for injectable drugs |
| Aruvant Sciences | , | Seems pulled into Roivant, Sep 2022 |
| Delpor | Brisbane, CA | Drug Delivery System |
| Polyaurum | , | Website down Jun 2021 - Dec 2021 |
| Tilos Therapeutics | , | Acquired by Merck, Jun 2019, up to $773M |
| Keros Therapeutics | Lexington, MA | Rare Muscle Disorders |
| Cambryn Biologics | , | Gone Apr 2020, facility bought by Akron Biotech |
| Ibis Biosciences | , | Acquired by Abbott Jan 2009 |
| Innovagen | Lund, Sweden | Custom antibody development |
| Hologic | Marlborough, MA | Diagnostic, Imaging |
| Hope Medicine | Pudong, China | Antibody Therapy |
| BHR Pharma | , | Subsidiary of Besins |
| GenSure | Shijiazhuang, China | Diagnostics |
| Onchilles Pharma | San Diego, CA | Biologics for Cancer |
| New England Cell Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| Biscayne Pharmaceuticals | , | Website Gone Nov 2018; Merged with Insero Health, Oct 2015. |
| Applied NeuroSolutions | , | Gone |
| tiakis Biotech | Kiel, Germany | Biologics |
| NuProbe | Houston, TX | Nucleic Acid Profiling & Diagnosis |
| Telavant | , | Acquired by Roche from Roivant, Dec 2023 |
| Immunicon | , | Bankrupt - Assets sold to Veridex, Jun 2008 |
| , | Renamed Hermes Biosciences | |
| Klogene Therapeutics | , | Gone 2019? |
| ICON plc. | Dublin, Ireland | Clinical Trials, Consulting |
| 21st Century Therapeutics | , | Website from 2011, drug was in phase 1 for at least six years if still active |
| Adherex Technologies | , | Changed name to Fennec Pharma, Sep 2014 |
| BigHat Biosciences | San Mateo, CA | BigHat designs safer, more effective biologic therapies using machine learning and synthetic biology |
| Excelra | Hyderabad, India | Data Science & Informatics Services |
| Intiva Biopharma | , | Renamed Nexien BioPharma, Oct 2018 |
| Shape Memory Medical | San Jose, CA | Devices using Shape Memory Polymer materials |
| Spirogen | , | Bought by AstraZeneca, Oct 2013 |
| Fovea Pharmaceuticals | , | Acquired by Sanofi Oct 2009 |
| Typharm | Norwich, UK | Generics |
| Zurex Pharma | , | Website down Mar 2025 - Aug 2025 |
| Vincerx Pharma | , | Winding Down, Apr 2025; fka Vincera Pharma; Went public via SPAC (LSAC) Oct 2020 |
| Tebubio | Le Perray-en-Yvelines, France | Kits, Reagents, Proteins, Services |
| Roche | Basel, Switzerland | Small Molecules |
| |
Latina, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Additive Orthopaedics | , | Acquired by Paragon 28, Jun 2021 |
| Biotest Labs | , | Acquired by/Merged with Steris |
| Odan Laboratories | Pointe-Claire, QC | Specialty Generics |
| Medtronic | Jacksonville, FL | Medical Devices |
| Caperna | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| PermeaDerm | , | Acquired by Stedical Scientific, Aug 2019 |
| Truvic Medical | , | Acquired by Imperative Care, Jul 2021 |
| CG Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| RSSL | Reading, UK | Analytical Services |
| DSK InnoSciences | Bangalore, India | Contract Chemistry Services |
| Cambridge Bioclinical | , | Failed to raise sufficient funds and dissolved 2008 |
| SanaVita Medical | Telford, PA | Contract manufacturing & device processing services for implantable biomaterials, controlled drug release, and combination products |
| Smart Medical Systems | , | Website taken over, Apr 2020 |
| FingerPrint Diagnostics | , | Merged with SmartBead Technologies to become Pronostics |
| Promea | Hyderabad, India | Diagnostics Manufacturing |
| Promore Pharma | , | Acquired by reverse merger, Dec 2023; fka Pergamum |
| Cypher Genomics | , | Acquired by Human Longevity, Dec 2015 |
| Corium | Kentwood, MI | Transdermal Generics, Consumer Products |
| Forest Devices | Pittsburgh, PA | Portable device using EEG and machine learning to diagnose large vessel occlusions and other stroke subtypes |
| Labopharm | , | Bought by Paladin 2011 |
| Predictive Biosciences | , | Closed 2013 |
| TomoTherapy | , | Bought by Accuray, Mar 2011, $277M |
| Leaf Expression Systems | , | Liquidating Mar 2025; Website down Feb 2025 - Mar 2025 |
| A-Alpha Bio | Seattle, WA | Yeast-based Drug Assay |
| Autonomous Therapeutics | Rockville, MD | Evolving Therapeutics for Lifelong Protection |
| Switch Therapeutics | South SF, CA | RNAi Therapies |
| NantCell | , | Renamed ImmunityBio |
| Gain Therapeutics | Lugano, Switzerland | Site-directed Enzyme Enhancement Therapy |
| APO-T | , | Website down Dec 2021 - Apr 2022 |
| Rhelixa | Tokyo, Japan | Epigenome Analysis |
| Axonia Medical | , | Gone 2015 |
| A&Z Pharmaceutical | , | Effectively renamed Allegiant Health |
| , | Website down Dec 2025 - Apr 2026 | |
| Sterigenics | Oak Brook, IL | Medical Device Sterilization |
| MaxCyte | Rockville, MD | Protein Production, Drug Discovery, Cell Therapy |
| Phylogica | , | Renamed PYC Therapeutics, 2019 |
| Orakl Oncology | Paris, France | Personalized cancer treatment technology |
| Regel Therapeutics | Berkeley, CA | AAV gene delivery |
| Mateon Therapeutics | , | Merged with Oncotelic Apr 2019; fka Oxigene |
| Aprecia Pharmaceuticals | Mason, OH | Zipdose formulation |
| Butterfly Network | New York, NY | Subscription Ultrasound Device |
| Stealthyx Therapeutics | , | Shut down Sep 2021 |
| Evocutis | , | Pivoted to investments |
| CDI Bioscience | , | Website Gone Oct 2016; Est 2000 |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Stamford Pharmaceuticals | Austin, TX | Immunotherapy |
| Neuroelectrics | Barcelona, Spain | Neurostimulation device |
| Diagnostic BioSystems | Pleasanton, CA | Immunohistochemistry, in-vitro Diagnostics |
| Nile Therapeutics | , | Merged with Capricor |
| Core Prognostex | , | Seems inactive |
| Dasgip | , | Acquired by Eppendorf, Jan 2012 |
| Eyetech | , | Website Gone 6-16-12 |
| ALSP | , | Website down Dec 2024 - Apr 2025 |
| Alnis BioSciences | , | No info |
| , | Website down Nov 2025 - Apr 2026 | |
| pH Pharma | , | Website down Feb 2025 - Jun 2025 |
| Cellular Biomedicine Group | , | Renamed AbelZeta Pharma, Nov 2023; aka CBMG |
| Tome Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Mawi DNA Technologies | Pleasanton, CA | Non-invasive DNA sampling technology |
| , | Acquired by Merck, May 2026, $6.67B | |
| Alimentiv | San Diego, CA | Clinical Services |
| bioMerieux | Cambridge, MA | Diagnostics |
| TRPHARM | , | Renamed Inpharmus, 2025 |
| Reaction Biology | Malvern, PA | Assay Services & Protein Production |
| |
Frankfurt, Germany | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Caprion Pharmaceuticals | , | Merged with Ecopia and became Caprion Therapeutics, Mar 2007 |
| Active Life Scientific | , | Website down May 2022 - Oct 2022 |
| DermBiont | Boston, MA | Topical Bacterial Products |
| Alcresta Therapeutics | Waltham, MA | Digestive enzyme device |
| Accellacare | Wilmington, NC | Clinical Research |
| Norphan Pharmaceuticals | , | Acquired by Marathon Pharmaceuticals, 2013 |
| Logan Medical Devices | , | Gone? |
| Oncternal Therapeutics | , | Winding down Jul 2025; Acquired GTx shell to go public Jun 2019; Merged with Tokalas, Jun 2016 |
| Aurealis Pharma | , | Website down Jul 2022 - Oct 2022; Seem to farm out candidates to new companies. First is Aurealis Therapeutics |
| Binacea Pharma | Hayward, CA | Cancer Antibodies |
| Organon | , | Bought by Schering-Plough Nov 2007, integrated into Merck post 2009 acquisition |
| Halozyme Therapeutics | San Diego, CA | Extracellular Matrix, Licensed out |
| Stada | Bad Vilbel, Germany | Generics |
| Exonics Therapeutics | , | Acquired by Vertex, Jun 2019, $245M |
| Google Life Sciences | , | Renamed Verily, Dec 2015 |
| Maxygen (2) | Newark, CA | Directed evolution services for protein engineering |
| Seno Medical Instruments | San Antonio, TX | Breast Cancer Diagnostic Imaging |
| Devsynthesis | Hyderabad , India | Chemistry CRO |
| , | Acquired by Crypto Group, Jan 2025 | |
| Triangle Research Labs | , | Acquired by Lonza, Jun 2016 |
| Immunodiagnostic Systems | Liège, Belgium | Immunoassay System |
| , | Website down Aug 2025 - Jan 2026 | |
| Raze Therapeutics | , | Closed due to complicated biology |
| Renovate Biosciences | Hyderabad, India | Organ Transport, Diagnostics |
| Divergence | , | Bought by Monsanto |
| Zoll | Chelmsford, MA | Medical Devices, Defibrillators |
| Lean Biologix | Norfolk, MA | Consulting |
| Xenome | , | Website Gone 7-14-13. All employees terminated. Seems viable as of Aug 2013, but employeeless. |
| Lubris Biopharma | , | No business filings, 2015-2021 |
| Poseidon CRO | Ariana, Tunisia | Clinical Research |
| GIPAM | Wismar, Germany | Market Access Consulting |
| Astellas | Yaizu, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Rhythm Pharmaceuticals | Boston, MA | Peptide Therapeutics |
| Vaccizone | Istanbul, Turkey | ASC Speck Technology |
| Excelsior Medical | , | Acquired by ICU Medical, Oct 2015 |
| miRecule | Gaithersburg, MD | microRNA Therapeutics for Cancer |
| MicroChannel Technologies | , | Shell became cryptocurrency company |
| |
Fontenilles, France | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Lifecode | , | Acquired by MedGenome, Feb 2016 |
| Curtana Pharmaceuticals | Austin, TX | Small Molecules targeting cancer stem cells |
| , | Acquired by TransCode Therapeutics, Oct 2025 | |
| NapticBio | , | Website down Feb 2021 - Aug 2021; Not a registered business in CA Jul 2019 |
| Hangzhou Adcoris Biopharmacy | Hangzhou, China | Bioconjugate Therapies, Antibodies, ADCs |
| Micro-Tech Endoscopy | Ann Arbor, MI | Endoscopic Solutions |
| Micelle BioPharma | , | Website down Oct 2021 - Feb 2022; fka Sancilio & Company |
| Admittance Technologies | , | Employees have other, more important jobs or have left and remain on website Feb 2020 |
| Advanced Memory Institute of NJ | , | Acquired by Cenexel, Aug 2021 |
| Lpath | , | Taken over by Apollo Endosurgery, reverse merger for ticker, Sep 2016 |
| Biointron | Metuchen, NJ | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| Hera Therapeutics | , | Renamed Antiva Biosciences |
| Cellevolve | , | Website down Nov 2024; business filings late Aug 2023 |
| Aurora Biosciences | , | Acquired by Vertex Pharmaceuticals, 2001 |
| Theseus Pharmaceuticals | , | Acquired by Concentra Pharmaceuticals, Feb 2024 |
| Freiberg Instruments | Freiberg, Germany | Measurement and automation solutions |
| Nooma Bio | , | Website down Jun 2024 - Dec 2024 |
| InSilico Solutions | , | Acquired by Kiromic, Jul 2021 |
| Minotaur Bio | , | Renamed Brightseed, Mar 2018 |
| Innovalve | , | Acquired by Edwards, Jul 2024, $300M |
| TamuroBio | , | Shut Down Jun 2024 |
| Intendis | , | Acquired by Bayer 2006, Renamed Bayer Health Care 2012 |
| Rebus Biosystems | , | Website down Apr 2025 - Sep 2025; fka Optical Biosystems |
| Nuredis | , | Shut Down Apr 2021 |
| EmpowerPharm | , | Shut down |
| Universal Precision Instruments, Inc. | , | |
| Wren Therapeutics | , | Dissolved 2024; Renamed WaveBreak, Apr 2023 |
| Biedermann Motech | Leeds, UK | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Bitome | , | Acquired by Ginkgo Bioworks, Jun 2022 |
| NanoEngineering Corp. | Branford, CT | Instruments for Nanodetection |
| Response Genetics | , | Acquired by Cancer Genetics, Aug 2015 |
| TrueBinding | Foster City, CA | Biotherapeutics |
| Ceiba Solutions | , | Bought by Perkin-Elmer, Mar 2015 |
| Polpharma | Starogard Gdanski, Poland | Generics |
| Axplora | Pompey, France | CDMO Services |
| Ontogen Medtech | Lisle, IL | Medical device development services |
| Raft Pharmaceuticals | , | Not registered in CA 2018- Sep 2021, seems to be professors who don't even list as a place of employment |
| Cell Genesys | , | Merged with BioSante |
| Alpine Biomed | , | Acquired by Natus, Sep 2009 |
| Osler Diagnostics | Oxford, UK | Finger stick blood test |
| |
Singapore, Singapore | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Pano Therapeutics | , | No business filings Apr 2020 - Nov 2023 |
| BioBlocks | , | Acquired by Genesis Drug Discovery, Oct 2021 |
| K5 Therapeutics | , | Folded into Muna Therapeutics, Jul 2021 |
| Protillion Biosciences | Carlsbad, CA | Therapeutic Protein Libraries |
| Dahlia Biosciences | , | Website gone Aug 2019 - Aug 2021 |
| Spago Nanomedical | Lund, Sweden | Tumor selective MRI agent; radionuclide cancer treatment |
| InterAx Biotech | Schlieren, Switzerland | Proprietary technology platform for the design and selection of GPCR-targeting compounds |
| Microbot Medical | Hingham, MA | Micro-robot assisted medical technologies |
| Genagon Therapeutics | , | Website gone Jan 2024 - Feb 2024; LI page gone Nov 2023 |
| Cytocell | , | Acquired by Oxford Gene Technology, Mar 2014 |
| miDiagnostics | Heverlee, Belgium | Diagnostics |
| OsteoCentric Technologies | Logan, UT | Mechanical Integration technology for orthopedic and dental implants |
| Cugene | Waltham, MA | Cancer and Inflammation Treatments |
| Aspen Pharmacare | Johannesburg, South Africa | Small Molecules |
| Yarra Therapeutics | , | No info Mar 2019 - Aug 2021; ArrayBio spinout, Dec 2017 |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| mimiX Biotherapeutics | Biel/Bienne, Switzerland | Sound Induced Morphogenesis to Shape Biological Elements |
| Omnimmune | , | Shell company, trademark abandoned |
| BWXT Medical | Ottawa, ON | Radiotherapies |
| , | Acquired by Inizio, Dec 2025 | |
| Jasper Therapeutics | Redwood City, CA | Humanized Monoclonal Antibody |
| , | Acquired by IQVIA | |
| Novelty Nobility | Seongnam, Korea | ADCs |
| , | Renamed Medley Therapeutics, Nov 2025 | |
| nContact | , | Bought by AtriCure $99M, Oct 2015 |
| Kymab | , | Acquired by Sanofi, Apr 2021, $1.45B |
| MYR Pharmaceuticals | , | Acquired by Gilead, Mar 2021, €1.1B + €300M milestones |
| Profectus Biosciences | , | Website down Oct 2020 - Apr 2021 |
| Rock Creek Pharmaceuticals | , | Chapter 7 Bankrupt, Sep 2016 |
| Novonesis | Bangalore, India | Enzymes |
| Janus Biotherapeutics | , | Website down Dec 2023 - May 2024 |
| Molecular Detection Inc | , | Gone 2016 |
| Genoma | , | Website gone May 2021 |
| Affina Biotechnologies | , | Website down Aug 2023 - Apr 2024 |
| Propagenix | , | Acquired by STEMCELL Technologies, Jan 2024 |
| Genvira Biosciences | Ottawa, ON | Viral Based Biotherapeutics Contract Work |
| , | Website down Dec 2025 - Apr 2026 | |
| Curoverse | , | Bought by Veritas Genetics, Aug 2017 |
| L7 Informatics | Austin, TX | Next Gen Sequencing software solutions |
| Sanofi | Waltham, MA | Small Molecules, Biologics |
| Durin Technologies | , | 2011 startup, no website Jun 2019 |
| Parasol Therapeutics | , | Renamed Visterra Inc in May 2010 |
| Pronutria Biosciences | , | Renamed Axcella Health, Jun 2016 |
| Anocca | Södertälje, Sweden | Individualized tcr and antigen cancer treatment |
| Piqur Therapeutics | , | Liquidating, Jun 2021 |
| AlleCures | , | Technically exists, one employee, Dec 2020 |
| ToolGen | Seoul, Korea | Genome Editing Technology |
| , | Acquired by Veralox Therapeutics, Jan 2025 | |
| Ascendis Pharma | Palo Alto, CA | Prodrug therapies |
| Codiak BioSciences | , | Selling assets through chapter 11 bankruptcy, Mar 2023 |
| CellectCell | , | Website Down Jan 2022 - Jun 2022 |
| Abnovel | , | Gone Jul 2010 |
| BlueSphere Bio | Pittsburgh , PA | T Cell Therapy |
| ITUS corp | , | Renamed Anixa Biosciences, Oct 2018 |
| Mirimus | Brooklyn, NY | CRISPR & RNAi to Create Animal Models |
| VentriFlo | Pelham, NH | Blood Pumping System |
| Victa Biotherapeutics | , | HiFiBio JV, No site Feb 2019 - Aug 2020 |
| Hypera Pharma | Cidade Jardim, Brazil | Generics |
| Raybow Pharmaceutical | Taizhou, China | Contract R&D |
| Droplet Genomics | , | Renamed Atrandi, Mar 2023 |
| SNBL CPC | , | Acquired by Pharmaron, Feb 2017 |
| VectorY Therapeutics | Amsterdam, Netherlands | Vectorized Antibodies |
| ImmBio | , | Shut down Nov 2019 |
| Spectra Medical Devices | , | Renamed Elevaris Medial Devices, Jan 2025 |
| Compass Biotech | , | Defunct |
| BPS Bioscience | San Diego, CA | Enzymes for Drug Discovery |
| TriWest Research Associates | Chula Vista, CA | Clinical Trials |
| Neon Therapeutics | , | Acquired by BioNTech, May 2020, $67M |
| GenScript | Piscataway, NJ | Genomics, Proteomics, Biologics |
| VisEn Medical | , | Acquired by PerkinElmer, 2010 |
| Pergamum | , | Changed name to ProMore Pharma, Jul 2016 |
| Biolytx Pharmaceuticals | , | Everyone has new/old jobs, Jun 2022 |
| Innovir Laboratories | , | Merged with VIMRx Pharmaceuticals, Dec 1996 |
| Mediso | Budapest, Hungary | Medical Imaging |
| Sunesis Pharmaceuticals | , | Acquired by Viracta Therapeutics, Feb 2021 |
| Bristol Myers Squibb | New Brunswick, NJ | Small Molecules, Biologics |
| ClearLight Diagnostics | , | Renamed ClearLight Biotechnologies, Oct 2018 |
| Porsolt | Le Genest-Saint-Isle, France | Contract Research |
| Ottobock | Königsee, Germany | Prosthetics |
| BioRelix | , | Restructured. Unknown Status. |
| Unicon Sciences | South Plainfield, NJ | Regulatory & Quality Consulting |
| AcelleRx | , | Renamed Juventas Therapeutics, Apr 2009 |
| Delpharm | Huningue, France | Contract Manufacturing |
| Fusion Antibodies | Belfast, UK | World Leading Antibody Services. Specialists in Discovery to Clinical Supply. |
| NeuroVista | , | Website Gone, President has new job |
| Atlantic Research Group | Charlottesville, VA | Clinical Research |
| Cure Foreward | , | Services suspended, May 2017 |
| DNAnexus | Mountain View, CA | Cloud-based genomic analysis |
| Spirox | , | Bought by Stryker, Jul 2017 |
| Pretzel Therapeutics | Waltham, MA | Mitochondrial Therapeutics |
| Apgene Bio | , | Shut down Oct 2020 |
| Bertek | , | Acquired by Mylan, Apr 1993, $39M |
| Processa Pharmaceuticals | Vero Beach, FL | Small Molecule |
| Kota Biotherapeutics | , | Shut down Jun 2021 |
| Eagle Genomics | Cambridge, UK | Genomics Software |
| ITF Pharma | , | Website down Dec 2023 - May 2024 |
| Fios Genomics | Edinburgh, UK | Bioinformatics and statistical analysis to support drug discovery, clinical trials & research studies worldwide. |
| Gene Express Inc | , | bankrupt? |
| Immunogenix | , | Website down Oct 2021 - Feb 2022 |
| Poochon Proteomics Solutions | Frederick, MD | Proteomics services |
| Avidimer Therapeutics | , | Flagship Ventures referring to them in past tense, Nov 2018; fka Nanocure |
| InkSure Therapeutics | , | Changed name to New York Global Innovations |
| , | Renamed Cofactory, pivoted, Mar 2024 | |
| Oncogen | , | Acquired by BMS, 1986 |
| CisThera | , | Shut down Jan 2023 |
| IpiNovyx Bio | Cincinnati, OH | Proteasome inhibitors to treat cancer, autoimmune and inflammatory diseases |
| Genmedica Therapeutics | , | Website taken over by Online Pharmacy Jan 2020 |
| Intergalactic Therapeutics | , | Website down Apr 2024 - Aug 2024 |
| Aviv Biomedical | , | Shut down 2018 |
| , | Website down Jan 2026 - May 2026 | |
| Zenyth Therapeutics | , | Acquired by CSL, Nov 2006 |
| Prothelia | , | Website down Sep 2022 - Feb 2023 |
| Known Medicine | Salt Lake City, UT | Custom micro-tumors from patient cells |
| Transcept Pharmaceuticals | , | Merged into Paratek, Oct 2014 |
| Patrin Pharma | Skokie, IL | Generics |
| Fosun Pharma | Paris, France | Small molecules, diagnostics, traditional |
| Prescos | , | Shut down Feb 2014 |
| SciFluor Life Sciences | , | Website down Sep 2020 - Feb 2021 |
| Avecris | Singapore, Singapore | Gene Delivery |
| BioCision | , | Acquired by Brooks, Nov 2016 |
| Viant Medical | Wilmington, MA | Contract Medical Devices |
| AchilleS Vaccines | , | Renamed Contraria Biotech, Jun 2024 |
| Solgate | Klosterneuburg, Austria | Solute Carrier-targeting Therapies |
| Italfarmaco Research | Milan, Italy | Pharmaceuticals and fine chemicals |
| Celine Therapeutics | , | Renamed Celine Biotechnologies |
| Tuodao Medical | Nanjing, China | Robotic Solutions for Surgery |
| Evotec | Hamburg, Germany | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Neovii Biotech | Grafelfing, Germany | Stem Cell Therapy, Biologics |
| Mova Pharmaceutical | , | Website not updated since 2009 as of Oct 2018 |
| Outlook Therapeutics | Iselin, NJ | Biosimilars |
| , | Website down Jan 2026 - May 2026 | |
| AbbVie | Clonshaugh, Ireland | Small Molecules, Biologics |
| Aleon Pharma | Parsippany, NJ | Regulatory Consulting |
| Griffin Laboratories | , | Acquired by Atos Medical |
| Kangpu Biopharmaceuticals | Shanghai, China | Small Molecules |
| Bio X Cell | West Lebanon, NH | Bulk antibodies |
| Seqalis | Gosselies, Belgium | Sequencing, pathology services, biobanking, genomics |
| Centrillion Technologies | Palo Alto, CA | Genomic Services |
| StemGuard Therapeutics | , | Gone Dec 2016 |
| Genomics Science Group | , | Website down Oct 2020 - Feb 2021 |
| , | Acquired by Affluent Medical, Feb 2026 | |
| Angiogenix | , | Endovasc subsidiary. Changed course in 2003, closed/liquidated in early 2005 after failed clinical trial |
| Outset Medical | San Jose, CA | Dialysis Device |
| Amnis Therapeutics | , | People left Mar 2019, Website down Jan 2020 - Feb 2020 |
| ICHOR Vascular | , | Merged with Pulse Therapeutics, Jan 2019 to become Euphrates Vascular |
| Enci Therapeutics | , | No website, business suspended by NC |
| Worldwide Clinical Trials | Tbilisi, Georgia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Siferon Therapeutics | , | Website gone Jul 2015 |
| Ariste Medical | , | Website down Sep 2021 - Feb 2022 |
| Jumpcode Genomics | San Diego, CA | CRISPR Genomic Technology |
| HDL Threadform | , | Renamed HDL Therapeutics, Mar 2011 |
| CZ Vaccines | Pontevedra, Spain | Vaccine CDMO |
| Acumed | Hillsboro, OR | Medical Implants |
| DNARx | , | business filings late Feb 2023 - Oct 2024; No news 2002-Oct 2024 |
| , | Acquired by InformedDNA, Mar 2025 | |
| Sanifit | , | Acquired by Vifor Pharma, Nov 2021, €205M + €170M milestones |
| DNA Labs International | Deerfield Beach, FL | Forensic DNA Analysis |
| LinaTech | Suzhou, China | Cancer treatment device |
| Labvantage | Somerset, NJ | Analytical Tests, Quality Solutions |
| Origen Therapeutics | , | Gone |
| Huabo Biopharm | Shanghai, China | Monoclonal antibody therapy, bispecific antibodies, and fusion proteins |
| Cergentis | , | Acquired by Solvias, Jul 2022 |
| Microbiologics | San Diego, CA | Diagnostics, Services |
| Be Biopharma | Cambridge, MA | Engineered B Cells |
| Biomonadic | Berkeley, CA | Klotho Gene Therapy |
| CanTx | , | Website gone, Feb 2015 |
| Scottish Biomedical | , | Renamed SB Drug Discovery |
| Avance Clinical | Firle, Australia | Clinical Research |
| Ocaro Pharmaceuticals | , | Website down Feb 2025 - Jul 2025 |
| Nexgen Arrays | , | Merged into NextView Diagnostics, Dec 2016 |
| , | Gone Jan 2025 | |
| Biomerics | Athens, TX | Medical device design & manufacturing |
| Pholoho Biotechnology | Shediac, NB | Algae Derived Research products |
| Kairos Therapeutics | , | Acquired by Zymeworks |
| Totus Medicines | Emeryville, CA | Covalent Small Molecules |
| Micrologix Biotech | , | Renamed Migenix |
| Spirometrix | , | Renamed Spirosure |
| Calico | South SF, CA | Aging treatments |
| Apexigen | , | Acquired by Pyxis Oncology, Aug 2023, $16M |
| AlloCure | , | Website Gone, Jul 2015 |
| BrainEver | Paris, France | Therapies for the treatment of neurodegenerative diseases |
| Overland Pharmaceuticals | , | Renamed Overland Therapeutics, May 2024 |
| Neomorph | San Diego, CA | Molecular glue drug discovery |
| ImmuneWorks | , | Website gone, Apr 2018 |
| SonoMotion | San Mateo, CA | Noninvasive Stone Treatment |
| Cell Therapy Ltd | , | Renamed Celixir |
| Integra Medical | , | Website gone Nov 2023 - Mar 2024 |
| Akamis Bio | Cambridge, MA | Oncolytic Vaccines |
| Theravant | , | Assets acquired by STRATA Skin Sciences |
| Qlucore | Lund, Sweden | Visualization Software |
| Life Stem Genetics | , | Basically gone |
| Janssen Biotech | , | Now part of Janssen Pharmaceuticals; fka Centocor |
| Corinthian Ophthalmic | , | Assets bought by Eyenovia, Oct 2014 |
| Alterna Therapeutics | , | Shut down Jan 2022 |
| TransCellular Therapeutics | , | Gone 2019 |
| Sprint Bioscience | Huddinge, Sweden | Cancer & Metabolism Therapies |
| HD Biosciences | , | Acquired by WuXi Apptec, Jan 2016 |
| OPX Biotechnologies | , | Acquired by Cargill, Apr 2015 |
| Genesys Spine | Austin, TX | Spinal Surgery Tools |
| Louisville Bioscience | , | Now LBIdx |
| ExeGi Pharma | Rockville, MD | Live Therapeutics |
| Evidera | , | Acquired by PPD, 2016 |
| DIVERCHIM CDMO | Roissy-en-France, France | Small Molecule Drug Substance CDMO |
| CTG Pharma | , | Gone |
| Eidogen-Sertanty | Oceanside, CA | Drug Discovery Software |
| Dundee Cell Products | , | Renamed DC Biosciences |
| Ribocure Pharmaceuticals | Mölndal, Sweden | RNA Therapeutics |
| Fertin Pharma | Vejle, Denmark | Oral Drug Delivery |
| APIS Assay Technologies | Manchester, UK | Oncology and infectious disease products, Contract Assay R&D, Bioinformatics Services, Clickmers |
| , | Website down Sep 2025 - Feb 2026; Pivoted from appliance recycling to non-opioid pain relief | |
| Igenomix | Miami, FL | Contract genetic testing for reproductive health; covid-19 pcr |
| Parcus Medical | , | Sold to Medacta Group, Mar 2025; Acquired by Anika Therapeutics, Jan 2020, $35M + $60M milestones |
| Sagetis Biotech | , | Website down Jul 2021 - Dec 2021 |
| Lonza | Porriño, Spain | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Acquired by Chiesi, Apr 2023 | |
| Charles River Laboratories | Saint-Constant, QC | Research Animal Models and Preclinical Research |
| BIT BIO Discovery | Vienna, Austria | iPSC, CRISPR Platform |
| Syndesi Therapeutics | , | Acquired by AbbVie, Mar 2022, $130M + $870M milestones |
| CureLab Oncology | Boston, MA | Anti-Cancer Biologics |
| Avania | Bilthoven, Netherlands | Medical Device Clinical Research |
| TherapeuticsMD | , | Licensed out product, laid off entire workforce, Dec 2022 |
| TiCARos Therapeutics | Seoul, Korea | Genetically Engineered T Cell Therapy |
| IPM Biotech | , | Acquired by BioAgilytix, Feb 2016 |
| |
Worcester, MA | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| AbbVie | Westport, Ireland | Contract Manufacturing |
| cGMP Validation | Huntersville, NC | Validation & Compliance Services |
| MEDARTIS | Basel, Switzerland | Implant Plates, Devices |
| Propel Biosciences | , | Website down Apr 2023 - Sep 2023 |
| Metri Bio | Boston, MA | Endometriosis Therapies |
| Sniper Medical Technologies | Suzhou, China | PCR System |
| Valeant Pharmaceuticals | , | Changed name to Bausch Health, Jul 2018 |
| Satiogen Pharmaceuticals | , | Acquired by Mirum Pharmaceuticals, May 2022 |
| Rivus Pharmaceuticals | Charlottesville, VA | Controlled Metabolic Accelerators |
| Xilio Therapeutics | Waltham, MA | Cancer Immunotherapies |
| Ares Genetics | , | Folded into OpGen, Dec 2021 |
| Gauss Surgical | , | Acquired by Stryker, Sep 2021 |
| Genecure | , | Shut down Sep 2021 |
| Clinical Network Services (Cns) | , | Acquired by Novotech |
| GenomeKey | Bristol, UK | IVD Device |
| Kratos Analytical | Manchester, UK | Lab Equipment |
| Antleron | Leuven, Belgium | Regenerative Medicine |
| Entrack Medical | , | Website down Dec 2019 - Oct 2020 |
| Eli Lilly | Boston, MA | Small Molecules, Biologics |
| Ridgeback Biotherapeutics | Miami, FL | Pediatric orphan and infectious diseases |
| , | Liquidating Feb 2025 | |
| Jeeva Informatics | Manassas, VA | eClinical SaaS platform |
| , | Acquired by XenoTherapeutics (nonprofit), Jan 2026 | |
| cmbio | Aalborg Øst, Denmark | Omics, Bioinformatics, Software Platforms |
| Smooth Drug Development | Wilmington, DE | Clinical Research |
| Immunodiagnostic Systems | Tyne & Wear, UK | Immunoassay System |
| Amneal Pharmaceuticals | Cashel, Ireland | Generic Small Molecules |
| Novalung | , | Merged with Medos, 2013 became Xenios |
| Inizio Ignite | New York, NY | Commercialization Consulting |
| Adeza Biomedical | , | Acquired by Cytyc, Apr 2007 |
| Novel Software Systems | Novosibirsk, Russia | Bioinformatics. NGS analysis. Software development for biology. Machine learning in medicine. |
| Eternans | , | Shut down Jul 2022 |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| Selten Pharma | , | Gone 2017 |
| Oncodesign Services | Dijon, France | Preclinical services |
| Viral Logic Systems Technology | , | Website taken over by debt payment company |
| Summit Biosciences | , | Acquired by Kindeva Drug Delivery, Jan 2024 |
| Getinge | Plewiska, Poland | Medical Technology |
| reMYND | Leuven, Belgium | Preclinical In-Vivo Alzheimer's Contract Research |
| Strategikon Pharma | San Francisco, CA | Digital tools for the business side of clinical trials. |
| Boston Biotech Clinical Research | Cambridgeshire, UK | Clinical Consulting |
| Clinipace | , | Renamed Caidya, Oct 2022 |
| Argolyn Bioscience | , | Bankrupt, Shut Down Jul 2009 |
| Kvvit Pharmaceutical | , | |
| Indigo BioAutomation | Carmel , IN | Lab Automation Software |
| Dr. Reddy's Laboratories | Hyderabad, India | Small Molecules, Custom Pharma Services |
| MSDx | , | Renamed ZelosDx, Jun 2021 |
| Biolyceum | , | Seems gone, Aug 2022; No filings after 2019 |
| ICBiotec | , | Acquired by eGenesis, May 2020 |
| Emerald Cloud Lab | Austin, TX | Cloud lab |
| HAYA Therapeutics | Lausanne, Switzerland | RNA-based, RNA-targeting Fibrotic Therapies |
| PregLem | , | Acquired by Richter, Oct 2010 |
| BAP Pharma | Donau, Germany | Clinical Supplies |
| , | Acquired by Insphero, Nov 2025 | |
| Synbal | , | Shut down per Linkedin page, likely Jul 2023 |
| Essen BioScience | , | Bought by Sartorius, Apr 2017, $320M; fka Essen Instruments |
| CellCap Technologies | , | Renamed CynapseDx, Oct 2016 |
| Aptalis | , | Acquired by Forest Labs, Jan 2014, $2.9B |
| Mirador Biomedical | , | Shut Down 2019 |
| Aseda Sciences | Schindellegi, Switzerland | Multi-parametric, high content, high throughput phenotypic screening and protein isolation services |
| Hovione | East Windsor, NJ | Contract Manufacturing |
| , | Website down Nov 2025 - Apr 2026 | |
| NuSirt Sciences | , | Appears to now be NuSirt Biopharma |
| Pulmovant | Waltham, MA | Inhaled mosliciguat |
| BionX Medical | , | Acquired by Ottobock |
| AblaCor | , | Shut down May 2019 |
| Bayer BioPartnering Solutions | Wuppertal, Germany | Biomanufacturing - recombinant protein and cell therapy modalities |
| Warp Drive Bio | , | Assets moved into Revolution Medicines, Sep 2018 |
| Sequentia Biotech | Barcelona, Spain | Bioinformatics, Genomics Analysis |
| Tidal Therapeutics | , | Acquired by Sanofi, Apr 2021, $160M + $310M milestones |
| Nexvet | , | Acquired by Zoetis, Jul 2017, $85M |
| AAIPharma | , | Merged with Cambridge Major Labs, renamed Alcami |
| Angelini Pharma | Rome, Italy | Disinfectants, Reformulated Small Molecules |
| Mistral Therapeutics | , | Surrendered Business License in Ca Dec 2019 |
| Empirical Bioscience | , | Acquired by Fortis Life Sciences, Oct 2021; fka Syzygy Biotech |
| Suros Surgical Systems | , | Bought by Hologic, Jul 2006, $240M |
| Capsulomics | , | Renamed Previse, Mar 2023 |
| Rapidemic | Leiden, Netherlands | Molecular Diagnostics |
| Advent Access | , | Presumed defunct; Website down Nov 2023 - Feb 2024 |
| Akribes Biomedical | Vienna, Austria | Wound Healing Therapeutic |
| MaveriX Oncology | , | Website down Mar 2023 - Dec 2023 |
| Acumed | Hampshire , UK | Medical Implants |
| PredictImmune | , | Shut down Nov 2023 |
| Chimagen Biosciences | , | Lead program acquired by GSK, Oct 2024. No info prior to then |
| o2h Discovery | Cambridge, UK | Drug discovery services |
| Dyno Therapeutics | Watertown, MA | AAV Engineering |
| Arthrosurface | , | Acquired by Anika Therapeutics, Feb 2020, $100M |
| Accurexa | , | Changed name to Medisun Precision Medicine, Jun 2017 |
| Allied Healthcare Products | , | Renamed Allied Medical, Dec 2023 |
| Vita Therapeutics | Baltimore, MD | iPSC |
| Sintalica Bioscience | , | Website down Feb 2025 - May 2025 |
| seqWell | Beverly, MA | Sequencing Service |
| Whole Biome | , | Renamed Pendulum Biosciences |
| Senesco Technologies | , | Renamed Sevion Therapeutics, Sep 2014 |
| Variation Biotechnologies | , | Now known as VBI Vaccines |
| Celtic Therapeutics | , | Changed name to Auven Therapeutics, Mar 2013 |
| Allenex | , | Bought by CareDx, Apri 2016 |
| Tapestry Pharmaceuticals | , | Gone |
| Acworth Pharmaceuticals | , | Shut down Jan 2024 |
| Solaris Biotech | Berkeley, CA | Specialized bioprocessing equipment for biotech, pharma, food + more. Benchtop / Pilot / Industrial Bioreactors, Fermenters, TFF. |
| Xione Therapeutics | , | Founder gone Oct 2021, no employees |
| ReShape Lifesciences | , | Merged with Vyome Therapeutics, Aug 2025; Acquired via Reverse Merger by Obalon Therapeutics, took this name |
| Biomere | Worcester, MA | Contract Research, Development, Manufacturing |
| NVIGEN | Santa Clara, CA | Nanoparticle Delivery for Imaging |
| Freyr Solutions | Princeton, NJ | Regulatory Consulting |
| Aposense | , | Renamed Interna TX, Sep 2024 |
| Dalton Pharma Services | Toronto, ON | Contract Manufacturing, Research, Chemical Sales |
| Keystone Nano | , | Renamed Pendrea Bio, Aug 2021 |
| Neuronax | , | Renamed Axoltis Pharma |
| UCB Pharma | Brussels, Belgium | Small Molecules, Biologics |
| EncepHeal Therapeutics | , | Shut down April 2022 |
| Degge Group | , | Acquired by PharmaLex, Apr 2014 |
| RBC Medical Innovations | , | Merged with Sterling Medical Devices to become Vantage MedTech, Sep 2023 |
| Altair Therapeutics | , | Shut down Feb 2011 |
| Mitos Pharmaceuticals | , | Website Gone |
| Bavarian Nordic | Berlin, Germany | Vaccines |
| Oncotide Pharmaceuticals | , | Website gone Oct 2017 |
| Imperial CRS | Grand Rapids, MI | Clinical Research Services |
| Iron Hills Therapeutics | , | Renamed Caravan Biologix |
| Noxxon Pharma | , | Renamed TME Pharma, Jun 2022 |
| Amigenics | , | Gone |
| Cornerstone Pharmaceuticals (2) | Monmouth Junction, NJ | Small Molecules, Delivery |
| Morepen Laboratories | Gurgaon, India | APIs, Diagnostics |
| CellGenix | , | Sartorius acquired majority stake, Jul 2021 |
| Proveri | , | Gone 2016 |
| Texcell | Shanghai, China | Contract Research |
| EAG Laboratories | Sunnyvale, CA | Analytical & Synthesis Services |
| Integrated Diagnostics (2) | , | Acquired by Biodesix, Jul 2018 |
| Renalytix | London, UK | AI-enabled Clinical Diagnostics |
| Ferring Pharmaceuticals | Parsippany, NJ | Small Molecules, Biologics |
| Synthes | , | Acquired by Johnson & Johnson, Jun 2012, $19.7B |
| PKPD International | , | Attack website |
| Acarix | Malmö, Sweden | Acoustic Cardiac Diagnostic Device |
| Molecular Profiles | , | Acquired by Columbia Labs, Sep 2013 |
| MedPharmics | , | Acquired by Velocity Clinical, Sep 2022 |
| 4Clinics | , | Acquired by P95, Jul 2024 |
| Sharp | Bethlehem, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Ventrus Biosciences | , | Merged with Assembly Pharmaceuticals Jul 2014 to become Assembly Biosciences |
| Biotia | Brooklyn, NY | AI Genomics |
| AstraZeneca | Cambridge, UK | Small Molecules, Biologics |
| GeneSegues | , | Website down Oct 2018 - Dec 2020 |
| EhmetDx | , | Renamed Ehmet Health |
| SINTX Technologies | Salt Lake City, UT | Silicon nitride-based materials and components for medical devices, orthopedic implants |
| CorEvitas | , | Acquired by Thermo Fisher, Jul 2023 |
| Kanvas Biosciences | Monmouth Junction, NJ | Microbiome Drug Discovery |
| QL Biopharm | Beijing, China | Biologics |
| Abbott | Princeton, NJ | Diagnostics |
| Pharos iBT | , | aka Pharos iBio |
| AllerGenis | Wynnewood, PA | Food Allergy Diagnostics |
| Numab Innovation | Horgen, Switzerland | Immunology, I-O drugs |
| Sinensis Life Sciences | , | Acquired by eurofins, Jan 2016 |
| Atlas Genetics | , | Renamed Binx Health |
| Visufarma | Amsterdam, Netherlands | Ocular Health |
| Resonance Medical Technologies | , | Website down Oct 2021 - Feb 2022 |
| PhenoPath | Seattle, WA | Diagnostic and contract research services |
| MODOC | , | Website down emails bouncing Oct-Nov 2018 |
| Personalis | Fremont, CA | Genome Services |
| Anavo Therapeutics | Leiden, Netherlands | Allosteric receptor modulators for a range of phosphatase targets |
| Medtech | , | Acquired by Zimmer Biomet, Jul 2016 |
| REPROMEDIX | , | Gone 2012 |
| Beijing Diagreat Biotechnology | Beijing, China | Diagnostic Reagents, DNA synthesis, RNA Services |
| Carver Biosciences | , | |
| Novasenta | Pittsburgh, PA | Antibody Drug Discovery via Single-Cell Tumor Analysis |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| GBI Biomanufacturing | Plantation, FL | Contract Biologics Manufacturing and Development |
| Sensidose | , | Acquired by Navamedic, Mar 2023 |
| Genisphere | , | Relaunched as Code Biotherapeutics |
| Astute Medical | , | Acquired by bioMérieux, Apr 2018, $90M |
| ReForm Therapeutics | , | Renamed Noveeda, Feb 2025 |
| Expression Patholgy | , | Now OncoPlexDx |
| CardioFocus | Marlborough, MA | Pulmonary vein ablation device |
| Arsia Therapeutics | , | Bought by Eagle Pharmaceuticals, Nov 2016, $30M + $48M milestones |
| nView Medical | Salt Lake City, UT | 3D Imaging During Surgery |
| Noramco | Wilmington, DE | Opiate-derived APIs & Reference Standards |
| CrestOptics | Rome, Italy | Fluorescence Microscopy and Diagnostic Applications |
| Turing Pharmaceuticals | , | Changed name to Vyera Pharmaceuticals |
| Civitas Therapeutics | , | Acquired by Acorda, Sep 2014, $525M. Formerly an Alkermes spinout. |
| Advanced Cancer Therapeutics | , | Sole asset failed early 2017 |
| Jiuzhou Pharma | Taizhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| OsteoGeneX | , | Website down Oct 2021 - May 2022 |
| Jazz Pharmaceuticals | Dublin, Ireland | Small Molecules |
| Karyosoft | Dallas, TX | Genomics Data Solutions |
| Celerion | Lincoln, NE | Clinical Research |
| Nine Continents Medical | , | Acquired by Coloplast, Oct 2020, $145M |
| Diteba Research Laboratories | , | Acquired by Nutrasource Diagnostics |
| Pharma Holdings | Tromsø, Norway | Respiratory Infection Treatments |
| Ingenus Pharmaceuticals | Denville, NJ | Drug Delivery modifications |
| JRF GLOBAL | Audubon, PA | Non clinical GLP research services |
| Pharvaris | Leiden, Netherlands | Small Molecules |
| Oculox Technologies | , | Website down Feb 2024 - Dec 2024 |
| , | Became part of Accelerator, Dec 2025 | |
| Telix Pharmaceuticals | Burnaby, BC | Radio immunotherapy |
| Monogram Biosciences | , | Bought by LabCorp 2009 |
| GenKOre | Daejeon, Korea | Gene-editing therapies |
| PhaseRx | , | Bankrupt Dec 2018, sold to Roivant Sciences Feb 2018, $800K |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Novotech | Mandaluyong, Philippines | Clinical Research |
| Maetrics | , | Merged with R&Q, 2020, renamed RQM+ |
| Myoposity Therapeutics | , | Gone |
| Kumuda | , | Website gone Mar 2023 |
| Eurofins BPT | Jacksonville, FL | BioPharma Product Testing |
| CSSi | , | |
| Crown Bioscience | Loughborough , UK | Drug Development |
| Forticell Bioscience | , | CEO was gone in 2010, still showing on company website in 2015 |
| Epredia | Kalamazoo, MI | Pathology Equipment |
| , | Shut down 2025 | |
| AstraZeneca | Baar, Switzerland | Biologics |
| Xgene Pharmaceutical | Shanghai, China | Small Molecule Dual-Targeting Conjugates for Pain |
| Sense Proteomics | , | Acquired by Oxford Gene Technology, Mar 2009 |
| Xenon Pharmaceuticals | Burnaby, BC | Small Molecules for rare genetic diseases |
| SciGenom | San Francisco, CA | Next-gen sequencing services, bioinformatics |
| Boston Biomedical | , | Renamed Sumitomo Dainippon Pharma Oncology, Jun 2020; Bought by Dainippon Sumitomo Pharma, Feb 2012, $200M plus milestones up to $2.4B |
| BioReference Laboratories | Elmwood Park, NJ | Genetic, Diagnostic Testing |
| InVitro Cell Research | New York, NY | Cancer Diagnostics, Research |
| Oraya Therapeutics | , | Absorbed into Zeiss, Jun 2016 |
| Skyline Medical | , | Changed name to Precision Therapeutics, Jan 2018 |
| Intelliseq | Murrieta, CA | Genome Informatics |
| , | Website 404 Sep 2025 - Apr 2026 | |
| Artera | Los Altos, CA | AI Diagnostics |
| BeBetter Med | Guangzhou, China | siRNA Therapeutics |
| Helomics | , | Division of Predictive Oncology; fka Precision Therapeutics |
| Lipotek | , | Doesn't seem active, Jul 2022 |
| Romark Laboratories | , | Website down Feb 2025 - Jul 2025 |
| Delpharm | Tours , France | Contract Manufacturing |
| Diabeloop | Grenoble, France | Artificial pancreas device |
| TreeFrog Therapeutics | Pessac, France | Cell Therapies |
| Angiolink | , | Acquired by Medtronic, Nov 2004 |
| Allucent | Cary, NC | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| TheoremDx | , | Bankrupt Feb 2020 |
| Blueprint Medicines | Cambridge, MA | Small Molecule Discovery |
| Scynexis | Jersey City, NJ | Small Molecules |
| Recludix Pharma | San Diego, CA | Programs targeting STAT3 and STAT6 |
| , | Website hijacked Oct 2025 | |
| Inorbit Therapeutics | , | Shut down Nov 2024 |
| EntroGen | Woodland Hills, CA | Molecular Diagnostics |
| Nuvig Therapeutics | Menlo Park, CA | Novel therapeutics that induce mechanisms of immune homeostasis and treat autoimmune diseases |
| Novella Clinical | , | Acquired by Quintiles, Sep 2013 |
| OmniGuide | Billerica, MA | Surgical technology |
| Apcer Life Sciences | London, UK | Consultants |
| Nilogen Oncosystems | Tampa, FL | Tumor Screening Platform |
| , | Website down Dec 2025 - Jun 2026 | |
| Samus Therapeutics | , | Website down Nov 2022 - Mar 2023; not registered in MA |
| Pharmiva | , | Merged with Peptonic, late 2023 |
| Oakrum Pharma | , | Website down Aug 2024; Chapter 11 Bankruptcy May 2023 |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Hrain Biotechnology | , | Website down Feb 2024 - Jul 2024 |
| Thera Neuropharma | , | No real employees, no news since 2016 as of Apr 2021 |
| Centrillion Biosciences | , | Renamed Centrillion Technologies |
| Integrium Clinical Research | , | Website down Jul 2024 - Dec 2024 |
| Tocris Bioscience | , | Acquired by Bio-Techne, 2011 |
| Avalign Technologies | Mentor, OH | Orthopedics & Surgical |
| 121 Bio | , | Gone mid 2016 |
| , | Website down Jun 2025 - Dec 2025 | |
| Orphazyme | , | Acquired by kemPharm, May 2022, $7.6M |
| Madera Biosciences | , | Shut down Aug 2020 |
| Pharmozyme | Sunnyvale, CA | Genetic sequencing technology |
| Bacterin | , | Rebranded Xtant Medical after acquiring X-Spine, Jul 2015 |
| Silgan Unicep | Spokane, WA | Contract Filling & Packaging |
| Aspen Pharmacare | Boxtel, Netherlands | Small Molecules |
| Zoll | Pawtucket, RI | Medical Devices, Defibrillators |
| Core Dynamics | , | Gone |
| AxoTect | , | Phantom company |
| Moderna Therapeutics | Cambridge, MA | RNA Therapies |
| Clear Labs | San Carlos, CA | Automated Next-Generation Sequencing Platforms for Pathogen Detection and Genomic Surveillance |
| Tranzyme Pharma | , | Merged with Ocera Therapeutics Jul 2013 |
| Vascular Solutions | , | Acquired by Teleflex, Dec 2016 |
| Elgia Therapeutics | , | Founded 2020, no business filings Jan 2022 - Oct 2024 |
| , | Website down Jan 2026 - May 2026 | |
| Werewolf Therapeutics | Watertown, MA | Cancer Treatments |
| Bio-Rad | Redmond, WA | Research & Diagnostic Products |
| Scipher Medicine | Waltham, MA | Diagnostics for medicine suitability |
| , | Shut down Jan 2025 | |
| Covant Therapeutics | Boston, MA | Covalent small molecules targeting post-translational modification sites |
| |
Origgio, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Lumigen | , | Bought by Beckman-Coulter, Oct 2006 |
| Orchid Cellmark | , | Acquired by LabCorp Dec 2011 |
| Virax | , | Renamed Prescient Therapeutics, Dec 2014 |
| Senior Scientific | , | Renamed Imagion Biosystems, Dec 2016 |
| High Point Clinical Trials Center | , | Website down Jul 2023 - Dec 2023 |
| InxMed | Beijing, China | Oncology Treatments |
| Nanogen | , | Now Epoch Biosciences |
| Tolarex | , | Renamed Enlivex Therapeutics |
| Sterling Pharma Solutions | Newcastle, UK | Contract Development & Manufacturing - APIs |
| Brii Biosciences | Durham, NC | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Underdog Pharmaceuticals | , | Renamed Cyclarity Therapeutics, Jun 2022 |
| Odyssey Thera | , | Shut down 2014 |
| Orthosensor | , | Acquired by Stryker, Jan 2021 |
| IDEAYA Biosciences | South SF, CA | Personalized Synthetic Medicines |
| Imugen | , | Acquired by Oxford Immunotec, Jul 2016, $22M |
| Traversa Therapeutics | , | Bankrupt |
| Supratek Pharma | , | Website gone Sep 2017 |
| Kandu | , | Merged with NeuroLutions, Apr 2025 |
| , | No news 2019 - Oct 2025 | |
| Pacira Pharmaceuticals | , | Renamed Pacira Biosciences, Mar 2019 |
| Avrygen | , | Website Gone, execs gone |
| Gerstel | Mülheim an der Ruhr, Germany | Automation |
| Prinston Pharmaceutical | Somerset, NJ | Generics |
| Folio Conversant | , | Merged into Discovery Life Sciences, Oct 2018 |
| Resolution Medical | Fridley, MN | Contract Medical Device Manufacturing & Design |
| Quantificare | Suwanee, GA | Medical Imaging |
| Amide Tech | Waltham, MA | Peptide Synthesis |
| Novitium Pharma | East Windsor, NJ | Generics |
| Biokit | , | Rolled into Werfen |
| Esperto Medical | Irvine, CA | Sonic Blood Pressure Measurement |
| EpiThany | , | Website down Nov 2023; Mentioned in NY Times, Oct 2022; Owner/CEO left 2021 |
| IVAX Diagnostics | , | Renamed ERBA Diagnostics, Jun 2012 |
| BrYet | Houston, TX | Amino Acid polymer-drug conjugate |
| TRAC | , | Merged with Pharmalex, Nov 2017 |
| Cohera Medical | , | Bankrupt, Oct 2018 |
| Wetlin Research Associates | , | Centerwatch only |
| Ribonomics | , | Sold to MBL International |
| Ramanomics | , | Renamed Vivid Dx, Apr 2025 |
| SEQENS | Porcheville, France | Pharmaceutical, cosmetics and fine chemical ingredients |
| TranS1 | , | Renamed Baxano Surgical |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Applied Surgical Robotics | , | Website down Apr 2025 - Sep 2025 |
| Clinical Scientist Group | , | Website gone, employee gone |
| Adlon Therapeutics | , | |
| Valo Health | Lexington, MA | Drug Discovery & Development Engine |
| PeriGen | Rishon LeZion, Israel | Perinatal Devices |
| Prestige Biologics | Singapore, Singapore | Antibody, Biosimilars, Vaccine Manufacturing |
| Intrepida Bio | , | Website taken over Dec 2020 - Oct 2021; fka Dauntless 2 |
| Orthocyte | , | Website gone Jan 2020 - Dec 2020, Lineage Cell Therapeutics subsidiary |
| Pharmaloz | Lebanon, PA | Contract Manufacturing |
| Theragnostics | , | Acquired by Ariceum Therapeutics, Jun 2023 |
| Medicyte | , | Changed name to Upcyte, Jun 2015 |
| Compugen | Holon, Israel | Biologics |
| , | Purchased by Denver International Business Corp, Jan 2019 | |
| Vincera Pharma | , | Renamed Vincerx Pharma, Jan 2021 |
| AngioDynamics | Latham, NY | Array of Medical Devices |
| Merck | Dundalk, Ireland | Small Molecules, Vaccines, Biologics |
| Port Therapeutics | Los Angeles, CA | Unsure of business |
| ATUM | Newark, CA | Gene Synthesis, Protein Expression and Engineering |
| Fabric Genomics | Oakland, CA | Computational genomics |
| Concentric Medical | , | Acquired by Stryker, Oct 2011 |
| Athena Neurosciences | , | Acquired by Elan, 1996 |
| Siegfried | Grafton, WI | Contract Drug Manufacturing, APIS, Development |
| Guardant Health | Palo Alto, CA | Biopsy-free Cancer Diagnostics |
| Potentia Pharmaceuticals | , | Acquired by Apellis Pharmaceuticals, Nov 2014 |
| Hemogenyx Pharmaceuticals | London, UK | Blood Stem Cell & Bone Marrow Transplantation |
| GeneCure Biotechnologies | , | Website dated 2008 as of Mar 2018 |
| Bonti | , | Bought by Allergan, Sep 2018, $195M |
| Ennaid Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| TargaGenix | , | Website down Feb 2023 - Apr 2023 |
| Isolation Bio | Palo Alto, CA | Microbial Cultivation Device |
| Natco Pharma | MEKAGUDA, India | Generics, APIs, Contract Manufacturing |
| Seachaid Pharmaceuticals | , | Gone 2016 |
| Bora CDMO | Wilmington, DE | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Protein Fluidics | Burlingame, CA | Microfluidic system that automates 3D-cell based (organoid) assays |
| Suzhou Stainwei Biotech | , | Website down Jan 2023 - May 2023 |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| SanaRx Biotherapeutics | , | Renamed Microbial Machines, May 2022 |
| alphaSyx Therapeutics | , | Gone |
| Ergomed | Kiev, Ukraine | Clinical Research |
| BriaCell Therapeutics | Philadelphia, PA | Immunotherapies |
| E3X Bio | , | Shut Down Mar 2019 |
| Intercytex | , | Company was gone, reincarnated with an identically named company. Aug 2017 doubtful it's for real |
| Jiuzhou Pharma | Zhongshan, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Hema Diagnostics Systems | , | Changed name to NuGenerex Diagnostics, Sep 2018 |
| PopCheck Technologies | Memphis, TN | Calf muscle stimulation device |
| LifeMine Therapeutics | Cambridge, MA | Fungi-derived therapeutics |
| Solos Endoscopy | , | Renamed CYduct Diagnostics, Dec 2020 |
| Myovant Sciences | , | Fully acquired by Sumitomo, Oct 2022, $2.9B; Majority Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B |
| Advion Bioanalytical | , | Bought by Quintiles, Nov 2011 |
| Biopure | , | Assets bought by OPK Biotech, Aug 2009 |
| mAbxience | Lugano, Switzerland | Biosimilar Monoclonal antibodies |
| CEL-SCI | Vienna, VA | Biologics |
| , | Website down Apr 2026; Filings late Feb 2026 | |
| Precision Neuroscience | New York, NY | Brain–computer interface implants |
| ADC Therapeutics | New Providence, NJ | Antibody-drug conjugates |
| Risen Pharma Tech | Shanghai, China | Small Molecules, siRNA, Combination Therapies |
| Mikrogen | Neuried, Germany | Diagnostics, Equipment |
| Fusion Biopharma | , | Presumed gone |
| Phytomedics | , | Can't find info on it |
| Myllia | Vienna, Austria | Phenotypic Drug Discovery |
| Brogent International | , | Website down Aug 2023 - Feb 2024 |
| Aikium | Berkeley, CA | AI Drug Discovery |
| Daiichi Sankyo | Rueil-Malmasion, France | Small Molecules |
| Kinovate | Oceanside, CA | Polymeric Supports for Nucleotide Synthesis |
| Kleiner Device Labs | Incline Village, NV | Spinal Implantation Devices |
| Affymax | , | Dissolved 2014 |
| Amneal Pharmaceuticals | Hyderabad, India | Generic Small Molecules |
| Valink Therapeutics | Cambridge, MA | Bispecific Antibodies |
| Advanced Innovative Partners | , | Website down Nov 2023 - Mar 2024 |
| Veeva Systems | Barcelona, Spain | Life Science Software |
| GenWay Biotech | , | Acquired by Aviva Systems, Feb 2017 |
| Diagonal Therapeutics | Watertown, MA | Agonist Antibodies |
| Aurora Biolabs | San Diego, CA | Recombinant Research Proteins |
| Capella Therapeutics | , | Website down Sep 2022 - Feb 2023 |
| Actualize Therapy | , | Founder gone, website five years stale Aug 2023 |
| Heraeus Medical | Hagen, Germany | Medical Devices |
| Travanti Pharma | , | Acquired by Teikoku Pharma, May 2009 |
| Syndax Pharmaceuticals | Waltham, MA | Tumor Phenotype Modification |
| Focus Therapeutics | , | Website down Apr 2021 - Sep 2021 |
| Bio-techne | Wallingford, CT | In-vitro diagnostics devices |
| OliX Pharmaceuticals | Seongnam, Korea | RNAi Treatments |
| Epicentre | , | Acquired by Illumina, Jan 2011 |
| Poly-Med | Anderson, SC | Absorbable Implants |
| Nexbio | , | Changed name to Ansun Biopharma 2014 |
| , | Website down Sep 2025 - Dec 2025 | |
| Telix Pharmaceuticals | Kyoto , Japan | Radio immunotherapy |
| , | Redirecting to Siemens, Feb 2026 | |
| Marengo Therapeutics | Cambridge, MA | Monoclonal Antibodies |
| Juvena Therapeutics | Redwood City, CA | Tissue Regeneration & Repair |
| Immunic Therapeutics | Grafelfing, Germany | Small Molecules |
| Satya | Hyderabad, India | Small Molecule |
| Sebia | Lisses, France | Electrophoresis |
| Crealta Pharmaceuticals | , | Acquired by Horizon Pharma, Dec 2015, $510M |
| Genomics | Oxford, UK | Human Genetics Platform |
| Phoenix Solutions | , | Renamed EXACT Therapeutics |
| VIP Pharma | , | fka Advent Pharmaceuticals; no info on whether active since name change |
| Brandwood Biomedical | , | Acquired by PharmaLex |
| Aquestive Therapeutics | Portage, IN | Drug Delivery Technology |
| PharmaLex | Hesse, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Pfizer | Hurley, UK | Consumer Healthcare |
| Everist Health | , | Website down Jul 2021, came back as a Covid symptom checker |
| Lonza | Little Chesterford, UK | Contract Manufacturing, Development; Lab Systems, Research Products |
| , | Acquired by hVIVO, Dec 2019 | |
| Molecular Medicine Bioservices | , | Acquired by SAFC |
| Biocrates | Innsbruck, Austria | Diagnostic Biomarkers |
| Haemostatix | , | Acquired by Ergomed, May 2016 |
| GeneQuantum | Suzhou, China | Antibody-drug conjugate |
| Cell Technology | , | Acquired by ICT |
| Insmed | Bridgewater, NJ | Inhalable Liposomal Therapeutics |
| QUANTRO Therapeutics | Vienna, Austria | Novel targeted therapeutics interfering with disease-causing transcriptional programs in cancer |
| NeuroSearch | , | Wound down 2012 |
| ACF Pharmaceuticals | , | 2015 spinout from Fannin, no website Dec 2019 |
| LEX Diagnostics | Melbourn, UK | POC Molecular Diagnostics |
| Cerulean Pharma | , | Bought by Dare Bioscience, Mar 2017 |
| Lineus Medical | Fayetteville, AR | Peripheral IV lines |
| Enanta Pharmaceuticals | Watertown, MA | Small Molecules |
| Onodera | Kanagawa, Japan | Gene Therapy |
| Tandem Diabetes | San Diego, CA | Touchscreen Insulin Pump |
| Biomomentum | Laval, QC | Biomaterials & Cartilage Testing |
| Kesmalea Therapeutics | London, UK | Targeted protein degradation platform |
| Dr. Reddy's Laboratories | Norcross, GA | Small Molecules, Custom Pharma Services |
| Brii Biosciences | Beijing, China | SIRNA, Biologics, Monoclonal Antibodies, Small Molecules |
| Ridge Diagnostics | , | New owner/name, Jul 2016, per former CEO |
| Alector | South SF, CA | Alzheimer's Antibody Treatments |
| Metabolomx | , | Claim to be HQ in Mountain View, but they are not a registered business in CA and they say you should contact them in FL. Not registered in FL either Jul 2015. fka iSense? |
| AltheaDx | , | Acquired by Castle Biosciences, Apr 2022 |
| TetraScience | Boston, MA | Scientific Cloud Software |
| Eos Biotechnology | , | Gone 2005 |
| Applied StemCell | Milpitas, CA | Genome Editing, CRISPR, TARGATT, iPSCs, Cell Line Engineering, Cell Lines |
| MLAB Biosciences | Needham, MA | Biologics |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Inhalox Technology | , | No news since 2006 as of Jan 2021 |
| Mana.bio | Tel Aviv, Israel | AI to Design Lipid Nanoparticles |
| Flexus Biosciences | , | Bought by BMS, Feb 2015, $800M + $450M milestones |
| SVA | Madison, WI | Biotechnology Management Consulting |
| CF PharmTech | Beijing, China | Specialty Respiratory Pharmaceuticals |
| Symphony Clinical Research | , | Website redirecting strangely Apr 2021 |
| Aditus Medical | Berlin, Germany | Spinal Implants, Bone Cement/Substitutes |
| OcuDyne | , | AMD Medical Device |
| Sebela Pharmaceuticals | Roswell, GA | Generics |
| CXR Biosciences | , | Acquired by Concept Life Sciences, Aug 2015 |
| Indica Labs | Albuquerque, NM | Pathology Image Analysis Software |
| Rejuveron | , | Renamed Centenara Labs, Sep 2024 |
| Gataca | , | Gone |
| Virtus Pharmaceuticals | , | Website down Jan 2024 - Aug 2024 |
| Keryx Biopharmaceuticals | , | Merged with Akebia, Dec 2018, took Akebia name |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| YMC Process Technologies | Devens, MA | Purification Technology |
| Schleifring Medical Systems | Elgin, IL | Medical Device Manufacturing |
| Vernay | Kennesaw, GA | Fluid Control Solutions |
| , | Website down Jan 2026 - May 2026 | |
| Pacific Edge | Hummelstown, PA | Cancer Diagnostics |
| Resonetics | Kettering, OH | Contract Medical Device Manufacturing & Development |
| Calyxo | Pleasanton, CA | Device for Kidney Stone |
| Jaguar Animal Health Solutions | , | Merged with Napo Pharmaceuticals, became Jaguar Health, Jul 2017 |
| Bionary Bioproducts | , | Website lapsed, Sep 2017 |
| Curium Pharma | Maryland Heights, MO | Nuclear Diagnostics & Medicine |
| Aclairo Pharma Dev. Group | Sterling, VA | Preclinical Study Management |
| Jiangsu Nhwa Pharmaceutical | , | No news 2016 - Aug 2024 |
| GI Dynamics | , | Renamed Morphic Medical, Jul 2023 |
| Cube Biotech | Monheim, Germany | Membrane Protein Stabilization |
| Leonard-Meron Biosciences | , | Acquired by Citius Pharmaceuticals, Mar 2016 |
| Akhu Therapeutics | , | Founded at least by 2014, no info, Website built using Constant Contact Dec 2020 |
| OncoPep | , | Website down Feb 2025 - Jul 2025 |
| Advanced Molecular Systems | , | Website Gone, Nov 2018 |
| Climb Bio | Wellesley Hills, MA | Treatments for neuronal Excitability Disorders |
| RegenmedTX | , | Reincorporated in Caymans, took new name inRegen |
| Epitome Biosystems | , | Assets acquired by Millipore, 2009 |
| Otomagnetics | Gaithersburg, MD | Magnetic Injector |
| ProPharma Group | Raleigh, NC | Consulting |
| , | Website down Jun 2025 - Dec 2025 | |
| physIQ | , | Website down Feb 2025 - Jul 2025 |
| Meril | Vapi, India | Medical Devices, Diagnostics |
| |
Worms, Germany | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| goBalto | , | Acquired by Oracle, Oct 2018 |
| Alumis | South SF, CA | Autoimmune Treatments |
| Santen | Osaka, Japan | Ophthalmics |
| SteroTherapeutics | Doylestown, PA | NASH treatments |
| Proveca Pharma | Manchester, UK | Small Molecule Pediatric Formulations |
| Angiotech Pharmaceuticals | , | Changed name to Surgical Specialties Corp Jun 2013 |
| Vici Health Sciences | Elkridge, MD | CDMO providing formulation development, regulatory services, and analytical testing |
| Celldex Therapeutics | New Haven , CT | Small Molecules, Biologics, Vaccines |
| , | No news 2019 - Jan 2026; Acquired by Immunor, Dec 2017 | |
| Mitokyne | , | Renamed Mitobridge |
| Ascend Biopharmaceuticals | , | Renamed Stamford Pharmaceuticals Jan 2020 |
| Portola Pharmaceuticals | , | Acquired by Alexion Pharmaceuticals, Jul 2020, $1.4B |
| Veeva Systems | Radnor, PA | Life Science Software |
| Pacific Clinical Research Medical Group | Upland, CA | Clinical Research |
| Chanelle Pharma | Amman, Jordan | Generics |
| Gero | Singapore, Singapore | Ai driven drug discovery |
| Nanosonics | Hamburg, Germany | Ultrasound |
| Analgesic Solutions | , | Acquired by WCG, Apr 2019 |
| NanoCellect Biomedical | San Diego, CA | Flow Cytometry Platform |
| , | Website down Jan 2026 - Mar 2026 | |
| SHEPHERD Therapeutics | , | Renamed Khora Therapeutics, Apr 2025 |
| Health Discovery Corporation | , | Website down Sep 2022 - Feb 2023 |
| Genhouse Bio | Suzhou, China | Small Molecule Cancer Therapies |
| TargeGen | , | Bought by Sanofi 2010 |
| APR Applied Pharma Research | Balerna, Switzerland | Drug Delivery Technologies |
| Perseid Therapeutics | , | Bought by Astellas May 2011 |
| Oncomark | , | Acquired by Cepheid, Dec 2021 |
| Genexine | Seoul, Korea | Biologics, DNA Plasmid Vaccine |
| Mirai Bio | Cambridge, MA | Genetic Medicine Platform |
| Evelo Biosciences | , | Dissolving, Nov 2023 |
| Dizal Pharma | Shanghai, China | Innovative Medicines |
| PsiThera | Watertown, MA | Oral Small Molecules |
| , | Website down Oct 2025 - Feb 2026 | |
| Chanshow Biotechnology | San Diego, CA | Lab Consumables |
| Amneal Pharmaceuticals | Glasgow, KY | Generic Small Molecules |
| MS Bioworks | Ann Arbor, MI | Protein mass spectrometry contract research |
| Cantargia | Lund, Sweden | Antibody-based Treatments |
| Novasep | , | Merged with PharmaZell & Farmabios to become Axplora, Oct 2022 |
| ProQR Therapeutics | Leiden, Netherlands | Oligonucleotide Therapy |
| CoStim Pharmaceuticals | , | Acquired by Novartis, Feb 2014 |
| Revivo Therapeutics | , | Website gone May 2024 - Sep 2024 |
| Winston Pharmaceuticals | , | Shell company, went out of real business in 2012 |
| Igyxos Biotherapeutics | Nouzilly, France | Monoclonal Antibody for Infertility |
| HORIBA Medical | Irvine, CA | Hematology, Hemostasis, Clinical Chemistry |
| Pace | Indianapolis, IN | Analytical Testing, CDMO |
| Recipharm | Höganäs, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Octapharma | Springe, Germany | Plasma Products |
| Chromaceutical Advanced Technologies | , | Dissolved 2012 |
| |
Toronto, ON | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Uniquity Bio | Malvern, PA | Monoclonal Antibody |
| Balance Therapeutics | , | Gone late 2020 |
| Miikana Therapeutics | , | Acquired by Entremed, Jan 2006 |
| Verastem Oncology | Needham, MA | Drugs Targeting Cancer Stem Cells |
| Anakuria Therapeutics | , | Acquired by Janssen, Feb 2022 |
| Cancer Insight | , | Renamed LumaBridge |
| BioRestorative Therapies | Melville, NY | Autologous Stem Cell Therapy |
| Pfizer | Kalamazoo, MI | Manufacturing |
| Ingenia Therapeutics | Watertown, MA | Antibody Therapies |
| Clover Biopharmaceuticals | Changxing, China | Biologics |
| CerTest Biotec | San Mateo de Gállego, Spain | Clinical IVD |
| Ginolis | Oulunsalo, Finland | Nanoliter precision dispensing & automation, Laboratory to Point of Care Diagnostics Manufacture |
| Cochlear | Macquarie Park, Australia | Cochlear Implants |
| Viant Medical | Vega Baja, PR | Contract Medical Devices |
| Societal CDMO | , | Merged into Bend Bioscience, Sep 2024 |
| nanoLinea | , | Website down Apr 2022 - Jul 2022 |
| P4 Therapeutics | , | Website down Feb 2025 - Jun 2025 |
| Asuragen | Austin, TX | Diagnostics |
| Lisata Therapeutics | Basking Ridge, NJ | Cell Therapy Technology |
| Cytokinetics | South SF, CA | Small Molecules |
| Vector Laboratories | Newark, CA | Blotting Products, Antibodies |
| Origo Biopharma | , | Acquired by Agomab, Oct 2021 |
| Codexis | Redwood City, CA | Enzymatic Manufacturing of siRNA Therapeutics |
| , | Shut down Oct 2023 | |
| Sirius Genomics | , | Gone |
| M3 Wake Research | Encino, CA | Clinical Research |
| Truly Technologies | Seattle, WA | Biomolecule Isolation Polymer |
| Cellular Approaches | , | Website gone May 2020, no employees on LI |
| Stryker | Salt Lake City, UT | Medical Devices |
| Guide Therapeutics | , | Website down Oct 2021 - Dec 2021; Acquired by BEAM Therapeutics, Feb 2021, $120M + $320M Milestones |
| Xigen | , | Liquidated 2025; Website down Jun 2021 - Oct 2021 |
| GeNext Genomics | , | Website down May 2021 - Sep 2021 |
| Prescription Alliance | , | Website down Apr 2021 - Sep 2021 |
| MedinCell | Jacou, France | API Delivery Gel |
| IMA Clinical Research | Tarrytown, NY | Clinical Sites |
| Curl Bio | , | Shut down Feb 2020 |
| Teleflex Medical | Markham, ON | Surgical and Medical Devices |
| OMBU Bio | , | Assets acquired by Boca Biolistics, Feb 2015 |
| Alaunus Biosciences | , | No website Aug 2018 - Aug 2021 |
| Oncotest | , | Acquired by Charles River, Nov 2015, €34M |
| Apaxis Medical | , | Gone 2019 |
| Collaborative Medicinal Development | , | Almost all employees gone, business filings late Jan 2023 - Jul 2024 |
| Biomira | , | Changed name to Oncothyreon, Dec 2007 |
| Horiba Instruments | Irvine, CA | Equipment |
| Catalent | Tampa, FL | Oral Dosage Manufacturing |
| Glide Technologies | , | Bankrupt, Aug 2017, assets bought by Enesi Pharma |
| Amberstone Biosciences | Irvine, CA | Solid Tumor Therapies |
| , | Filings late May 2023 - Nov 2025; Website down Nov 2025; fka T-Rx Pharmaceuticals | |
| Resonetics | Or Akiva, Israel | Contract Medical Device Manufacturing & Development |
| NexImmune | Gaithersburg, MD | Nanoparticle AIM Therapy, Cell Therapies |
| Kestrel Therapeutics | Watertown, MA | Targeted therapy for RAS-drive cancers |
| Pharmalink | , | Renamed Calliditas Therapeutics, 2017 |
| , | Renamed Until Labs, Oct 2025 | |
| Aeres Biomedical | , | Gone Jul 2013 |
| TopAlliance Biosciences | Menlo Park, CA | Monoclonal Antibody |
| Octapharma | Stockholm, Sweden | Plasma Products |
| Alveo Technologies | Alameda, CA | Diagnostic Devices |
| BC Technical | , | Acquired by AlphaSource, Nov 2017 |
| Clarity Diagnostics | Deerfield Beach, FL | Diagnostics |
| |
Miami, FL | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Miami is a stand-alone full service Clinical Trials Unit, with a safety lab and a PBMC lab. |
| Stallergenes Greer | Antony, France | Allergen Desensitization |
| Varro | Saint Louis, MO | Open-source, breath-based diagnostic devices |
| Sinsan Pharmaceuticals | Pune, India | Small Molecules |
| iVexSol | Lexington, MA | Lentiviral vectors |
| Essential Pharma | Egham, UK | Generics |
| IGI Laboratories | , | Changed name to Teligent, Oct 2015 |
| Integer | Juarez, Mexico | Medical & Surgical Devices |
| Glactone Pharma | , | Website down May 2021 - Oct 2021 |
| Focal Medical | , | Acquired by Continuity Biosciences, Jun 2025 |
| Charles River Laboratories | Saffron Walden, UK | Research Animal Models and Preclinical Research |
| South Coast Clinical Trials | , | Website gone |
| Heraeus Medical | Yardley, PA | Medical Devices |
| Novian Health | Evry, France | Device for breast tumor ablation |
| Ablitech | , | Website Gone 12-10-13, No longer a tenant at last known office |
| Medical Microinstruments | Pisa, Italy | Microsurgery System |
| Elastagen | , | Acquired by Allergan, Feb 2018, $95M |
| Validars Bioscience | , | No filings 2018-2021; No website Nov 2019 - May 2021 |
| , | Acquired by Aptean, Oct 2016 | |
| ZS Genetics | , | Merged with Genetics Research, Jul 2017 |
| Karos Pharmaceuticals | , | Sold to Roivant Sciences, 2017 |
| EzDiatech | Anyang-si, Korea | Diagnostic Solutions |
| Origent Data Sciences | Vienna, VA | Clinical Data Management, Analysis |
| BIND Therapeutics | , | Filed Chapter 11 bankruptcy, May 2016, Assets bought by Pfizer for $40M |
| Peptimmune | , | Liquidated 2011 |
| Piramal | Hyderabad, India | CDMO |
| Cytiva | Marlborough, MA | Medical Devices |
| CordenPharma | Boulder, CO | Contract peptides, complex small molecules, highly active compounds |
| Alida Biosciences | San Diego, CA | Epigenetic analysis tools |
| Ironshore Therapeutics | , | Acquired by Collegium, Sep 2024 |
| MicroMed | , | Acquired by Natus, Jan 2023 |
| Princeton Center for Clinical Research | , | Website not working, Aug 2020; no LI employees |
| Terumo Medical | Leverkusen, Germany | Medical Devices |
| Neuracle Science | Seoul, Korea | Antibody Therapies |
| ICON plc. | Raleigh, NC | Clinical Trials, Consulting |
| Huntingdon Life Sciences | , | Rebranded as Envigo, 2015 |
| Guided Delivery Systems | , | Rebranded as Ancora Heart Inc Oct 2016. |
| CutisPharma | , | Renamed Azurity Pharmaceuticals, Jun 2019 |
| Kinetix Pharmaceuticals | , | Bought by Amgen 2000 |
| Infex Therapeutics | Alderley, UK | Treatments for Pandemic Infections |
| |
Glen Mills, PA | 400+ projects, 30+ years of impact—see how Everest simplifies biopharma commercialization. Let’s connect. |
| Virtici | Seattle, WA | Product / Company Incubator |
| Atlantic Therapeutics | , | Acquired by Caldera Medical, Sep 2023 |
| Vanessa Biotech | , | CEO convicted of wire fraud, sentenced to 10 years in prison, Feb 2025 |
| Slope Clinical | Norfolk, VA | Clinical Trial Platform |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| VWR | , | Bought by Avantor Sciences, Nov 2017, $6.5B |
| Loci Orthopaedics | Galway, Ireland | Thumb Implant |
| Synostics | , | Gone 2014 |
| Enzene Biosciences | Pennington, NJ | Biosimilars, peptides |
| AcuPharma Solutions | Mississauga, ON | Contract Research, Manufacturing & Consulting |
| Earli | Redwood City, CA | Early cancer biomarker detection |
| Acumed | Madrid, Spain | Medical Implants |
| Elicio Therapeutics | Boston, MA | HPV-induced cancer treatments |
| Critical Outcome Technologies | , | Changed name to Cotinga Pharmaceuticals, Jan 2018 |
| MiProbes | , | Website down Apr 2022 - Aug 2022 |
| Immunethep | Cantanhede, Portugal | Immunotherapies for Bacterial Infections |
| HistoRx | , | Acquired by Genoptix Sep 2012 |
| Xpira Pharmaceuticals | , | Website down Apr 2025 - Sep 2025 |
| Eurobio Scientific | Les Ulis, France | Diagnostics, Reagents, Screening Kits, Media |
| Quris Technologies | Tel Aviv, Israel | AI Drug Discovery |
| Kiurebro Life Sciences | , | Website not working, Sep 2017 |
| Dandelion Science | Epalinges, Switzerland | AI neuromodulation platform |
| ReproCELL | Kanagawa, Japan | Cell Culture Reagents & Antibodies |
| Dirui Industrial | Changchun, China | Automated Assays |
| Viant Medical | Foxborough, MA | Contract Medical Devices |
| Freudenberg Medical | Jeffersonville, IN | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| iN Therapeutics | Gyeonggi, Korea | Ion channel targeting drugs |
| Red5 Pharmaceuticals | , | No info, No website Dec 2019, Red5 Pharma website taken over by viagra spam |
| |
Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Altogen Labs | Austin, TX | GLP-compliant laboratory that provides preclinical research services |
| Nutromics | San Diego, CA | Wearable Diagnostic Device |
| eXoZymes | Monrovia, CA | Enzyme Systems for Biomanufacturing |
| ImmuONE | Stevenage, UK | Organ Models, Services |
| Lungpacer Medical | Exton, PA | Diaphragm Pacing Therapy |
| Cebert Pharmaceuticals | , | Gone, Mar 2015 |
| CS Bio | Menlo Park, CA | Peptide Synthesizers & Custom Synthesis |
| Taros Chemicals | Dortmund, Germany | CRO for small molecule drug-discovery and performance chemicals R&D challenges in Germany and India |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| CinderBio | San Leandro, CA | Proteases for proteomics analyses |
| Ajinomoto Althea | , | Sold to PCI Pharma Services, Apr 2025; Merged with OmniChem to become Ajinomoto Bio-Pharma Services, Oct 2018 |
| Officinae Bio | Venice, Italy | RNA. DNA Design Platform |
| Molecular Logix | , | Gone, Dec 2018 |
| PharmCADD | Busan, Korea | AI Drug Development Platform |
| Gateway Genomics | , | Acquired by Myriad Genetics, Nov 2022 |
| Pulse Biosciences | Hayward, CA | Nano-pulse Stimulation Device |
| Ranbaxy | , | Merged with Sun Pharma, Mar 2015 |
| CellnTec Advanced Cell Systems | Bern, Switzerland | Culture media, reagents |
| Morphic Rock Therapeutic | , | Pretty sure this is just Morphic Therapeutics |
| Accell Clinical Research | St. Petersburg, Russia | Clinical Research |
| PhageTech | , | Website gone Aug 2024; Business filings late Dec 2022 - Aug 2024 |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Viwit | Shanghai, China | APIs, Formulation |
| IDA Therapeutics | , | Had 2016 Jlabs spot. No website Aug 2018. |
| Liveome | Suwon, Korea | Microbiome Therapeutics for Intractable Diseases |
| Allorion Therapeutics | Guangzhou, China | Small molecule drugs against cancer and autoimmune diseases |
| NAMSA | Tokyo, Japan | Medical Research Organization - Medical Devices |
| Bioheart | , | Seem to have taken on the identity of a company they invested in called U.S. Stem Cell |
| TrakCel | Cardiff, UK | Gene & Cell Therapy Services |
| Ony Biotech | Amherst, NY | Non-invasive Neonatal Therapies |
| Wockhardt | Parsippany, NJ | Specialty Dermatology, Generics |
| Northern Bio | Muskegon, MI | CRO that specializes in targeted drug delivery, molecular biology, and bioanalysis |
| Sapio Sciences | Baltimore, MD | Web-based LIMS |
| Ascendance Biotechnology | , | Acquired by BioIVT, Mar 2018 |
| Pfizer | Budapest, Hungary | Small Molecules, Biologics, Vaccines |
| Xell | , | Acquired by Sartorius, Aug 2021, €50M |
| BioTrove | , | Acquired by Life Technologies, Dec 2009 |
| BioPharmX | , | Acquired via Reverse Merger by Timber Pharmaceuticals, May 2020 |
| OncoSenX | , | Employees are all Oisin employees 2020-2025. Seems like a fake "spinout" |
| Hayat Pharmaceutical | Amman, Jordan | Generics |
| Flow Forward Medical | , | Acquired by Artio Medical, Jul 2020 |
| Delpharm | Poznań, Poland | Contract Manufacturing |
| Graffinity Pharmaceuticals | , | Seems gone Jul 2015 |
| BioReliance | , | Bought by Sigma-Aldrich, Jan 2012, $350M |
| Artiva Biotherapeutics | San Diego, CA | NK Cell Therapies for Cancer |
| Apotex Fermentation | , | Gone, facility acquired by Cronos group |
| , | Website down Oct 2025 - Feb 2026 | |
| ElMindA | , | Renamed Firefly Neuroscience, Nov 2023 |
| Novelix Pharmaceuticals | , | website gone, company still marked as active in CA company database |
| Intelomed | , | Website down Aug 2024 - Feb 2025 |
| Ology Bioservices | , | Acquired by Resilience, Apr 2021 |
| Rain Therapeutics | , | Renamed Rain Oncology, Dec 2022 |
| Allievex | , | Shut down Feb 2025 |
| Maven Biotechnologies | , | Website down Jun 2021 - Jan 2022 |
| NuGenerex Immuno-Oncology | , | Website down Nov 2022 - Mar 2023; fka Antigen Express |
| Confluent Medical Technologies | Alajuela, Costa Rica | Contract Medical Devices, Nitinol, Catheters, Textiles |
| AmCyte | , | Acquired by ReNeuron, Aug 2007, $4M |
| Photocure | Oslo, Norway | Diagnostics & Small Molecules |
| Targeted Therapeutic Solutions | , | Seems gone Aug 2022 |
| Rezon Bio | Duchnice, Poland | Analytics, development, GMP manufacturing, and formulation |
| Enumeral Biomedical | , | Evicted, out of money Aug 2017, filed bankruptcy Feb 2018 |
| Acologix | , | Closed Aug 2011 |
| Accentus Medical | Oxford, UK | Medical Device Implant Coatings |
| Hemacare | , | Acquired by Charles River Labs, Jan 2020, $380M |
| Merus | Utrecht, Netherlands | Immuno-Oncology |
| Forth Therapeutics | Edinburgh, UK | Next-generation precision therapeutics for fibrosis |
| Bolder Surgical | , | Acquired by Hologic, Nov 2021, $160M |
| CoImmune | , | Website down Dec 2023 - May 2024 |
| Genzyme Genetics | , | Bought by LabCorp, Dec 2010 |
| Daiichi Sankyo | Shanghai, China | Small Molecules |
| AGT Biosciences | , | Merged into Chemgenex, Apr 2004 |
| Spectrum Dynamics | Sarasota, FL | Advanced imaging |
| ChemPartner | Shanghai, China | Life Sciences Contract Research |
| Padagis | Allegan, MI | Generics |
| , | Website down Jul 2025 - Dec 2025 | |
| Angiosyn | , | Acquired by Pfizer 2005 |
| Novacta | , | Website Gone, no info |
| TrovaGene Oncology | , | Renamed Cardiff Oncology, May 2020 |
| Ciron Drugs | Mumbai, India | Contract Small Molecule Manufacturing |
| Nihon Kohden | Tokyo, Japan | Medical Electronic Equipment |
| DoMore Diagnostics | Oslo, Norway | Personalized AI Medicine |
| Oxford Gene Technology | Oxford, UK | Assays & Analysis |
| Artielle ImmunoTherapeutics | , | Website copyright 2011 as of Mar 2019 |
| AureoGen Biosciences | , | No activity 2015-2022, no employees on LI |
| Oculgen | Shenzhen, China | Gene and cell therapies, biologics, vaccines |
| Roji | , | Website down Dec 2021 - Jul 2022 |
| AveXis | , | Acquired by Novartis, Apr 2018, $8.7B |
| Hoya Surgical Optics | Singapore, Singapore | Development and manufacturing of advanced intraocular lenses |
| NAMSA | Obernburg am Main, Germany | Medical Research Organization - Medical Devices |
| Allozyne | , | Broken up and sold off, Sep 2014 |
| Lonza | Basel, Switzerland | Contract Manufacturing, Development; Lab Systems, Research Products |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Emergex Vaccines | , | Renamed Gylden Pharma, Oct 2024 |
| AMSBIO | Massagno, Switzerland | Numerous assays, reagents and lab tools of all types |
| VitroScan | Leiden, Netherlands | Tumor Analysis for Treatment Matching |
| |
Melbourne, Australia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Integer | Chaska, MN | Medical & Surgical Devices |
| Whale Imaging | Waltham, MA | Ultrasound, Surgical Imaging |
| Kymos Group | Barcelona, Spain | Contract Development Lab |
| Newsummit Biopharma | , | Website down Jan 2020 - Jul 2020 |
| Laboratorio Teuto | Anápolis, Brazil | Small Molecule Generics |
| Transcell Oncologics | , | Website taken over, Apr 2023 |
| Sepiatec | Berlin, Germany | Separation Systems |
| INTEGRA Biosciences | Hudson, NH | Liquid Handling, Pipettes |
| |
Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Getinge | La Ciotat, France | Medical Technology |
| RSIP Vision | Jerusalem, Israel | Image analysis algorithms |
| UVLrx Therapeutics | , | Website gone, Dec 2019 |
| Bicara Therapeutics | Boston, MA | Dual-Action Biologics, Antibodies |
| Eisai | Nutley , NJ | Small Molecules |
| Breethe | , | Acquired by Abiomed, Apr 2020 |
| Unum Therapeutics | , | Renamed Cogent Biosciences, Oct 2020 |
| Team Consulting | Cambridge, UK | Medical technology design and development consultancy |
| Scendea | Bishop's Stortford, UK | Product Development & Regulatory Consulting |
| Regeneron | Rensselaer, NY | Small Molecules, Biologics |
| Pieris Pharmaceuticals | , | Merged with Palvella Therapeutics, Dec 2024 |
| Vimed | , | Renamed Alpinion Medical Systems, 2010 |
| Paratek Pharmaceuticals | King of Prussia, PA | Small Molecules |
| Previvo Genetics | , | Website down Jan 2021 - May 2021 |
| Altis Biosystems | Durham, NC | Stem cell platform that recreates the human intestinal epithelium in a high-throughput format for drug screening and microbiome research |
| NuProbe | Shanghai, China | Nucleic Acid Profiling & Diagnosis |
| SuperGen | , | Changed name to Astex Pharmaceuticals |
| CASI Pharmaceuticals | San Francisco, CA | Small Molecules |
| MetaOptima | Vancouver , BC | Skin Analytics |
| Itamar Medical | Caesarea, Israel | Sleep Apnea Diagnostic Device |
| Koios Medical | New York, NY | Ultrasound breast cancer detection and diagnosis |
| NanoSort | , | Renamed NanoCellect |
| Chrysalis | Morrisville, NC | GMP Space |
| Helixmith | Seoul, Korea | plasmid DNA based gene therapy |
| Truvian Sciences | San Diego, CA | Automatic Diagnostic Test |
| Amunix Pharmaceuticals | , | Acquired by Sanofi, Feb 2022, $1B + $225 milestones |
| Jeyou Pharma | Wuxi, China | Drug Discovery Platform |
| Veravas | Oakdale, MN | Diagnostics |
| Phitonex | , | Acquired by Thermo Fisher, Jan 2021 |
| Antabio | Labège, France | Antibacterial drugs |
| Cardiovasc | , | Changed name to Nfocus Neuromedical |
| Acuitive Technologies | Allendale, NJ | Synthetic Biomaterials |
| Gyroscope Therapeutics | , | Acquired by Novartis, Dec 2021, $1.5B |
| Eberbach Labtools | Van Buren Charter Township, MI | Equipment for Mixing, Shaking, Blending, etc |
| Cato Research | , | Renamed CATO-SMS |
| Encoded Genomics | , | Renamed Encoded Therapeutics, 2019? |
| Penwest | , | Bought by Endo |
| , | Website down Oct 2025 - Feb 2026 | |
| PhoenixSongs Biologicals | , | Website down Jun 2023 - Dec 2023 |
| , | Acquired by Sorrento Therapeutics, Sep 2020 | |
| Rishi Pharmaceuticals | , | Gone 2017 |
| Stromatec | , | Website Gone, Mar 2017; SBIR |
| Ensera | Selangor , Malaysia | Device Manufacturing, Pharmaceutical Packaging |
| , | Acquired by Pretzel Therapeutics, Jan 2026 | |
| InChromatics | , | Website gone Sep 2022 - Jan 2023 |
| Agendia | Amsterdam, Netherlands | Breast Cancer Assay |
| Lykan Bioscience | , | Merged with RoslinCT, Aug 2022 |
| Novosteo | , | Acquired by Cortexyme, May 2022 |
| ArmaGen | , | Acquired by JCR Pharmaceuticals, Apr 2020 |
| dfnet | Seattle, WA | Clinical Data Management & Analysis |
| Alder BioPharmaceuticals | , | Acquired by Lundbeck, Oct 2019, $1.95B |
| ImmuVen | , | Website gone, Dec 2015 |
| Berlin-Chemie | Berlin, Germany | Small Molecules |
| Irvine Scientific | , | Acquired by Fujifilm, Jun 2018 |
| PX Biosolutions | , | Gone |
| , | Acquired by Lilly, Mar 2026, $1.2B | |
| Revvity | Hopkinton, MA | Diagnostics, Services |
| IceCure Medical | Caesarea, Israel | Cryoablation of Cancerous Tumors |
| Alnylam Pharmaceuticals | Cambridge, MA | RNAi |
| ABL Diagnostics | Woippy, France | Diagnostic Assay, Software |
| Refined Diagnostics | Münster, Germany | Lasers |
| Jeyou Pharma | Hangzhou, China | Drug Discovery Platform |
| Therapeutics Inc. | San Diego, CA | Dermatology Drug Development Services |
| Alebund Pharmaceuticals | Shanghai, China | Renal Therapies |
| Alva Health | New Haven, CT | Remote Stroke Monitoring |
| New River Pharmaceuticals | , | Acquired by Shire, Apr 2007, $2.6B |
| DART Therapeutics | , | Changed name to Akashi Therapeutics, Jun 2014 |
| Life in Genomics | , | Website down Apr 2024 - Aug 2024 |
| , | Merged with Intricon to become Forj Medical, Oct 2025 | |
| AnHeart Therapeutics | , | Acquired by Nuvation Bio, Apr 2024 |
| Natus Medical | Middleton, WI | Medical Devices, software |
| Larrk Bio | , | Website down Feb 2023 - Jul 2023; Stealth Jun 2020 |
| Genitope | , | Wound Down |
| Navigo Proteins | Halle, Germany | Proteins for purification and therapeutic use |
| Verix Health | , | Renamed Serpex Medical |
| Dova Pharmaceuticals | , | Acquired by Swedish Orphan Biovitrum, Nov 2019, up to $915M |
| Ikotech | , | Closed Dec 2015 |
| Immunocodex | Boston, MA | Nanoparticle-based Therapies |
| Assertio Therapeutics | Lake Forest, IL | Reformulated Small Molecules |
| BridGE Genomics | , | Gone 2022 |
| ViroMedica Pacific | , | Changed name to ViroMed, 199? |
| CAPS Medical | Netanya, Israel | Minimally invasive non-thermal plasma device for cancer treatment |
| Sharp | Lee, MA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Seaport Therapeutics | Boston, MA | Neuro Discovery Platform |
| Augmenta Biologicals | , | Website Gone May 2014 |
| Actylis | Port Washington, NY | Raw Materials |
| Telix Pharmaceuticals | Angleton, TX | Radio immunotherapy |
| Intellect Neurosciences | , | Effectively defunct after 2018 |
| Nueon Medical | , | Presumed Gone, Nov 2016 |
| Aixial Group | Montpellier, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Gene Solutions | , | Website down Dec 2022 - Apr 2023 |
| Byondis | Nijmegen, Netherlands | Antibody-Drug Conjugates, Monoclonals |
| BDR Pharmaceuticals | Hyderabad, India | APIs, New Age Formulations |
| Incline Therapeutics | , | Acquired by The Medicines Company, Dec 2012 |
| Ventana | , | Acquired by Roche, Jan 2008 $3.4B |
| BioProcess Technology Consultants | , | Acquired by BDO USA, Apr 2019 |
| , | Acquired by Alkermes, Oct 2025; $2.1B | |
| IONIQ Sciences | , | Shut down Oct 2024; aka ProLung |
| Kiecana Clinical Research | , | Now KCR |
| , | Website down Aug 2025 - Jan 2026 | |
| neuroloop | Freiburg, Germany | Vagus Nerve Simulation |
| Jasco Pharmaceuticals | , | Business revoked 2013, though they moved in 2015 |
| Tarrex Biopharma | , | Website down Sep 2021 - Jan 2022 |
| Eli Lilly | Indianapolis, IN | Small Molecules, Biologics |
| Medicure | Holetown, Barbados | Small Molecule |
| Relevant Bio | , | Shut Down Oct 2023 |
| Integra LifeSciences | Andover, UK | Medical Devices |
| , | Merged with DefiniGEN to become pixl.bio | |
| Lupin | Mumbai, India | Generics |
| 159 Solutions | , | Acquired by IQVIA, May 2018 |
| Cedilla Therapeutics | , | Shut down May 2023 |
| KangaBio | Shanghai, China | Multi-specific biologics |
| Qlibrium | , | Sold tech, shut down Dec 2024; fka Cam Med |
| Pacific Pharmaceuticals | , | Merged with ProCept Inc, Dec 1998 |
| Averion | , | Now Aptiv |
| GnuBIO | , | Bought by Bio-rad |
| Tasrif Pharmaceutical | , | Doesn't seem active, Apr 2023 |
| Pherecydes Pharma | , | Merged with Erytech Pharma, Jun 2023, became PHAXIAM Therapeutics |
| Advanced Cooling Therapy | , | Renamed Attune Medical |
| ChemoMetec | Allerod, Denmark | Cell Counters |
| NascaCell | , | German Aptamer company, not sure of fate |
| Cyagen Biosciences | Santa Clara, CA | Contract research; Rodent models, DNA vectors, Stem Cell Products |
| Orion Bioscience | , | Website down Sep 2022, no real employees |
| Ochre Bio | Oxford, UK | siRNA liver drugs |
| Taueret Laboratories | , | Acquired by Predictive Technology Group, Mar 2019 |
| Softhale | , | Website down Sep 2021 - Jan 2022 |
| Ekteino | , | Closed, Dec 2016 |
| CanImGuide Therapeutics | , | Website gone Nov 2022 |
| Infors | Basel, Switzerland | Bioreactors, Shakers, Cell Culture Equipment |
| Locus Biosciences | Morrisville, NC | CRISP-engineered Bacteriophage Therapeutics |
| Serán Bioscience | Bend, OR | CDMO, recognized as a world leader in conventional and enabling drug product development technologies |
| Pearl Bio | Cambridge, MA | Synthetic biology to build next-gen biomaterials for smart biologics |
| Novodiax | Hayward, CA | Companion Diagnostics, IVD & RUO 10 min Intraoperative IHC |
| Zalicus | , | Merged with Epirus, Jul 2014 |
| Torbay Pharmaceuticals | Devon, UK | Sterile Contract Manufacturing |
| Cingulate Therapeutics | Kansas City, KS | CNS treatments |
| NS Pharma | Paramus, NJ | Small Molecule |
| On Target Laboratories | West Lafayette, IN | Small molecule image-guided Surgery |
| Sapient Therapeutics | , | Renamed Avata Biosciences, May 2024 |
| GL Synthesis | Worcester, MA | Chemical Synthesis & Production |
| Putney | , | Acquired by Dechra, Mar 2016 |
| ChRi Laboratories | St. Paul, MN | Contract Lab Testing |
| Graegis Pharmaceuticals | , | Gifford Bioscience | Preclinical CRO specializing in receptor pharmacology and occupancy assays, for target validation and lead optimization in drug discovery |
| AM2PAT | , | Trouble with contaminated products, gone |
| CyBio | , | Merged into Jena, Jul 2014 |
| Kyn Therapeutics | , | Rebranded as Ikena Oncology, Dec 2019 |
| Genezen | Indianapolis, IN | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| ADAX | Ljubljana, Slovenia | Clinical Monitoring |
| Maverick Therapeutics | , | Acquired by Takeda, Oct 2021, $525M |
| Sopherion | , | Website taken over, Mar 2017 |
| Corza Medical | Shanghai, China | Surgical Devices |
| Sibreax | , | Website down Jan 2021 - May 2021 |
| AB Biosciences | Concord, MA | Reagents, some protein research for therapeutic discovery |
| Medice | Iserlohn, Germany | Small Molecules |
| Cell Signaling Technology | Danvers, MA | Antibodies, ELISA kits, research products |
| Trine Pharmaceuticals | , | Closed 2008 |
| LQT Therapeutics | , | Renamed Thryve Therapeutics, Jul 2022 |
| Uh-Oh Labs | Santa Clara, CA | Portable PCR-quality Diagnostics |
| Distek | North Brunswick, NJ | Lab Testing Instruments |
| 2SD Toxicology Services | Durham, NC | Biocompatibility and toxicology testing of medical devices and diagnostic products |
| Noven Pharmaceuticals | Miami, FL | Small Molecules |
| Elion Oncology | , | Exclusively licensed product to Processa Pharmaceuticals |
| Biokine Therapeutics | , | No news 2014 - Apr 2025 |
| APIE Therapeutics | , | Gone Jun 2025 |
| Precigen | Germantown, MD | Cell & Gene Therapy |
| GSK | Laval, QC | Small Molecules, Vaccines, Biologics |
| BioNanomatrix | , | Renamed BioNano Genomics |
| Curium Pharma | Boston, MA | Nuclear Diagnostics & Medicine |
| , | Acquired by Xoma, Nov 2025 | |
| Axter Therapeutics | Beijing, China | Small Molecules for Oncology |
| A3 Surgical | , | No website, seems gone as of May 2019 |
| Helio Vision | , | Bought by Aldeyra Therapeutics, Jan 2019, $10M |
| OncoSynergy | , | Acquired by Enochian BioSciences, Apr 2016 |
| Maribo Medico | , | Acquired by ResMed, Nov 2015 |
| Vitaeris | , | Bought by CSL Behring, Jun 2020 |
| Androvia Life Sciences | , | Website down Nov 2022 - Mar 2023 |
| SHL Medical | Zug, Switzerland | Medical Device assembly, labeling, packaging |
| Quintiles | , | Renamed QuintilesIMS, Oct 2016 |
| Shanti Clinical Trials | , | Only info is on Centerwatch |
| Microbiologics | Lexington, KY | Diagnostics, Services |
| , | Crypto Pivot Jan 2025; fka Neurotrope | |
| CuriRx | Wilmington, MA | CRO offering development services for upstream and downstream bioprocess, formulation, lyophilization, analytical development, analytical testing services |
| HydroCision | North Billerica, MA | Saline Jet Device |
| ProUroCare Medical | , | Gone |
| Argos Therapeutics | , | Relaunched as CoImmune 2019; Filed Chapter 11 Bankruptcy Dec 2018; fka Dendritix, fka Merix Bioscience |
| WuXi Apptec | Shanghai, China | All types of contract work for small molecules, devices |
| Shantani | Pune, India | Small Molecule Target Identification, Biologic Characterization |
| ClinChoice | Horsham, PA | Contract research - data management, biostatistics, clinical operations, regulatory, safety, pharmacovigilance, toxicology, medical affairs, medical writing, quality, risk, and compliance |
| Inspirna | , | Shut down Mar 2025; fka RGenix |
| Mabqi | Grabels, France | Antibody Discovery |
| , | Website down Oct 2025 - Feb 2026 | |
| SERB Pharmaceuticals | Brussels, Belgium | Specialty Pharmaceuticals |
| Retinal Solutions | , | Renamed Caeregen Therapeutics, Aug 2021 |
| Nymirum | , | Renamed Base4, Feb 2023 |
| Lazarus Effect | , | Acquired by Medtronic, Sep 2015, $100M |
| Launchpad Therapeutics | , | |
| Podimetrics | Somerville, MA | Diabetic Foot Ulcer Detection |
| Bristol Myers Squibb | Manati, PR | Biologics |
| Philogen | Monteriggioni, Italy | Small Molecules, Biologics, ADCs |
| AlphaHelix | , | Renamed Level Bio, May 2024 |
| BoroPharm | , | Website down Sep 2022 - Feb 2023 |
| Akshaya BIO | , | Website down Mar 2022 - Sep 2022 |
| Predigen | , | Employees all gone Aug/Sep 2021 |
| Teleflex Medical | Seoul, Korea | Surgical and Medical Devices |
| , | Website down Jun 2025 - Dec 2025 | |
| Lorantis | , | Merged with Celldex 2005 |
| Valerius Biopharma | , | Website down Dec 2024 - May 2025 |
| Stago | Asnières sur Seine, France | Diagnostics |
| Orphan Therapeutics | , | Gone Mar 2010 |
| Siegfried | Nantong, China | Contract Drug Manufacturing, APIS, Development |
| Ellab | Hillerød, Denmark | Validation & Monitoring |
| OncoTEX | , | Website down Aug 2022 - Jan 2023 |
| Moma Therapeutics (1) | , | Regenerative Medicine - gone post 2009 |
| AbFero Pharmaceuticals | , | Acquired by Pharmacosmos, Nov 2021, $225M |
| Accuratus Lab Services | , | Now part of Analytical Lab Group; fka ATS Labs |
| Clinical Research Services Turku | Turku, Finland | Clinical Research |
| Epineuron | Mississauga, ON | Bioelectric Therapy |
| Alithea Genomics | Epalinges, Switzerland | RNA Sequencing |
| Boston Bioprocess | Champaign,, IL | Fermentation & Downstream Development and Optimization |
| Invitae | , | Acquired by Labcorp, Apr 2024; Chapter 11 Bankruptcy, Feb 2024 |
| Mymetics | , | Dissolved Jul 2024; Sold Biosimilars, Mar 2022 |
| ICN Pharmaceuticals | , | Now Valeant |
| Baliopharm AG | , | Acquired by Promethera Biosciences, Apr 2018 |
| Heraeus Medical | Dorado, PR | Medical Devices |
| Baylis Medical Technologies | Fort Worth, TX | Radiofrequency guidewires, transseptal needles, microcatheters, and vascular access sheaths |
| Drusolv Therapeutics | , | Website gone Aug 2017 |
| Vante BioPharm | , | Rebranded at Sebra |
| iCad inc | , | Acquired by RadNet, Apr 2025, now part of DeepHealth |
| Focal Therapeutics | , | Acquired by Hologic, $125M, Oct 2018 |
| Medidata Solutions | New York, NY | Clinical Trial Software |
| NewBridge Pharmaceuticals | Dubai, UAE | In-licensing, marketing to Africa, Middle East |
| Thermo Fisher | Oslo, Norway | Molecular Biology & Biotech Lab Products |
| Proteon Pharmaceuticals | Lodz, Poland | High-Throughput Screening |
| BlueRock Therapeutics | Cambridge, MA | Stem Cell Therapies |
| M3 Biotechnology | , | Renamed Athira Pharma, Apr 2019 |
| Kalia Health | Chapel Hill, NC | Preeclampsia Test |
| Noucor Health | Barcelona, Spain | Small Molecules |
| Vascular Insights | , | Assets acquired by Merit Medical, Jan 2019 |
| Blue Water Vaccines | , | Renamed Blue Water Biotech, Apr 2023 |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| Athlon Pharma | , | No news since 2006 lawsuit |
| , | Website down Jan 2026 - May 2026 | |
| Pharming Group | Leiden, Netherlands | Biologics |
| AbbVie | Bangalore, India | Small Molecules, Biologics |
| Hologic | Santa Clara, CA | Diagnostic, Imaging |
| American Regent | Shirley, NY | Generics |
| CNS Research | , | Seem gone, 2020 |
| Uvax Bio | Newark, DE | Single-component self-assembling protein nanoparticle vaccine |
| Neuralstem | , | Renamed Seneca Biopharmaceuticals, Oct 2019 |
| Flex Pharma | , | Merged with Salarius Pharmaceuticals, Jul 2019, took name |
| Cosette Pharmaceuticals | Bridgewater, NJ | Generics |
| Meribel Pharma Group | Parets, Spain | Contract Manufacturing |
| Polymedco | Cortlandt Manor, NY | Colorectal Cancer Screening |
| Criterium | Saratoga Springs, NY | Clinical Research |
| Galectin Therapeutics | Norcross, GA | Small Molecules |
| Cmxtwenty | , | Website down Apr 2023 - Sep 2023; Seem to be successor to Cytometix |
| SutroVax | , | Renamed VaxCyte |
| Dornier MedTech | Barcelona, Spain | Urology Devices |
| Accellacare | Raleigh, NC | Clinical Research |
| Link Health Group | , | Website down Nov 2023 - Mar 2024 |
| Saryna Technologies | , | Website gone Jul 2020, Not registered with CA. Sold some equipment via auction Sep 2017. |
| HT Medical | , | Renamed Xenix Medical, Apr 2021 |
| Synmabtix | , | Website down Jan 2021 - May 2021 |
| Qualia Pharma | , | Website down Feb 2024 - Sep 2024 |
| Cellectis | New York, NY | Genetic 'Surgery' Therapeutics |
| VGXI | The Woodlands, TX | DNA plasmid contract manufacturing |
| ZY Therapeutics | , | Dissolved Oct 2024 |
| Quetzal Therapeutics | Chicago, IL | Oral arsenic trioxide therapy |
| Sanofi | Haverhill, UK | Small Molecules |
| ZyGEM | , | Renamed MicroGEM |
| AMB Surgical | , | Website down Jul 2021 - Dec 2021 |
| Vascular Pharmaceuticals | , | Shut down 2018 |
| Avalign Technologies | Portland, OR | Orthopedics & Surgical |
| Cairn Biosciences | San Francisco, CA | Live cell assays |
| GreenLight Biosciences | Medford, MA | Renewable Chemicals |
| Resilience | San Diego, CA | Biomanufacturing |
| One Drop | , | Gone Dec 2024 |
| Omnia Biologics | , | Website gone Sep 2017 |
| Evofem Biosciences | San Diego, CA | Women's health |
| NeuTec Pharma | , | Shut down 2010 |
| Gestala | Dengdu, China | Brain-computer Interfaces |
| Hikma | Berkeley Heights, NJ | Medication Delivery |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ora | Tukwila, WA | High-throughput live animal screening and machine learning |
| Ace Biosciences | , | Acquired by Zymenex, Nov 2009 |
| Entrega | , | Website Gone, Aug 2017, company still filing annual reports into 2019 |
| , | Shut down Mar 2026 | |
| |
South SF, CA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| South Coast Clinical Trials | , | |
| Kite Pharma | Oceanside, CA | Engineered Autologous T Cell Therapy, CAR-T |
| Chemeleon | Brooklyn, NY | Ultra-rapid, instrument-free cardiac troponin assay |
| Pathos AI | Chicago, IL | In-Licensing Clinical Drugs |
| Falcon Pharmaceuticals | , | Bought by Sandoz from Alcon Oct 2011 |
| Histogenics | , | Merged with Ocugen, Sep 2019 after exploring strategic options |
| Musculoskeletal Clinical Regulatory Advisers | Manchester, CT | Clinical Research Consulting |
| Siamab Therapeutics | , | Achieved "Exit" with unnamed biopharma company, Aug 2019 |
| Agouron Pharmaceuticals | , | Acquired by Warner-Lambert, Jan 1999, $2.1B stock |
| Verrow Pharmaceuticals | , | Acquired by Ligand Pharmaceuticals, Jan 2018, $2M |
| Reactive Biosciences | Durham, NC | Boron-based Discovery |
| Rakovina Therapeutics | Vancouver, BC | Small Molecules |
| Affectis Pharmaceuticals | , | Website down Jul 2022 - Nov 2022; Max Planck spinout. Ingenium Pharmaceuticals sends you here |
| , | No news 2017 - Apr 2026 | |
| Microfluidic ChipChop | Jena, Germany | Lab-on-a-chip, Microfluidics |
| MLM Medical Labs | Oakdale, MN | Clinical Lab |
| Polypeptide Therapeutic Solutions | , | Renamed Curapath, Oct 2022 |
| Smartox Biotechnology | Saint Martin d’Hères, France | Peptide-based drug discovery |
| Ossianix | Hertfordshire, UK | Biotherapeutic products using the highly versatile single domain VNAR antibody from the shark |
| BioCydex | , | No info 2019 - Mar 2025 |
 |
Atlanta, GA | Formulation development, clinical trial supplies, analytical development, cGMP clinical & commercial manufacturing/packaging |
| R-Pharm US | Princeton, NJ | Acquiring Small Products |
| EVerZom | Paris, France | Exosome Therapeutics |
| G6 Spine | , | Gone 2017 |
| Fresenius Kabi | Isola della Scalla, Italy | Contract Manufacturing |
| CBA Pharma | , | Website gone May 2025; Company under fraud investigation May 2025 |
| Vivani Medical | Alameda, CA | Implantable Drug Delivery Systems |
| WPD Pharmaceuticals | , | Shell company, Apr 2024 |
| MagnaBioSciences | , | Website down Apr 2025 - Sep 2025 |
| ExeVir | Ghent, Belgium | Llama-derived antibodies |
| AllGene | , | No info, Feb 2019 - Aug 2021 |
| Samphire Neurosciences | London, UK | Electrostimulation Device |
| ImmunoFrontier | , | Very old, amateurish site, likely not active |
| Priaxon | , | No news in six years as of Mar 2019. No employees on LinkedIn |
| Boston Scientific | Spencer, IN | Medical Devices |
| Seeker Biologics | , | Shut down May 2023 |
| Proteolytics | , | Website password protected, Dec 2019 - Mar 2020 |
| 21MedTech | , | Website down May 2022 - Jun 2022 |
| SG Devices | , | Website gone Jan 2023 - Jul 2023 |
| Bioneeds | Bangalore , India | Contract Research |
| West Pharma | Cornwall, UK | Pharmaceutical Supplier |
| Genesis Clinical Research | Tampa, FL | Nephrology Clinical Trials |
| Curetis | , | Merged with OpGen, Feb 2021 |
| Awareness Technology | Palm City, FL | Automated Analyzers |
| Owl Biomedical | , | Website down Apr 2025 - Jul 2025; Acquired by Miltenyi, Apr 2013 |
| Rose Medical | Grand Rapids, MI | Medical Device Manufacturing |
| Cytena | Freiburg, Germany | Single cell 'Printing' |
| Atalanta Therapeutics | Boston, MA | RNAi therapeutics |
| Verona Pharma | London , UK | Small molecules for respiratory indications |
| , | Products licensed out; fka UR-1 Therapeutics; Fortress Biotech company | |
| , | Website down Sep 2025 - Feb 2026 | |
| Rimasys Group | Cologne, Germany | Surgical Simulation |
| Best Nomos | Pittsburgh, PA | Brachytherapy |
| MSD | Brinny, Ireland | Small Molecules |
| Latus Therapeutics | , | Website down Jun 2024 - Nov 2024 |
| Acino | Zurich, Switzerland | Novel drug delivery formulations |
| Duopharma Biotech Bhd | Klang, Malaysia | Generics? |
| Tribiosys | , | Appears defunct, likely late 2007 |
| Innovative BioTherapies | , | Gone |
| ClinSpec Diagnostics | , | Renamed DxCover, Jun 2021 |
| Retia Medical | White Plains, NY | Heart Monitor Algorithm |
| Restek | Bellefonte, PA | LCGC Equipment |
| , | Website down Jul 2025 - Dec 2025 | |
| Medicago | , | Acquired by Mitsubishi Tanabe, Sep 2013, $357M |
| Sonablate | Charlotte, NC | HIFU Surgical Ablation Systems |
| Itherx | , | Bankrupt, changed name to get out of paying debts, lost court case. Apparently gone. |
| Pierre Fabre | Paris, France | Oncology, derm / cosmetics |
| Idun Pharmaceuticals | , | Acquired by Pfizer Feb 2005, Acquired by Conatus Pharmaceuticals Aug 2010 |
| Julphar | Ras Al Khaimah, UAE | Small Molecules, Biologics |
| DBV Technologies | Châtillon, France | Epicutaneous immunotherapy for allergic desensitization |
| Aldea Pharmaceuticals | , | No updates since 2014, no employees on LinkedIN |
| AsclepiX Therapeutics | , | 14 year side project for professors, emails bouncing Jun 2025 |
| Rhythm Xience | , | Acquired by Acutus Medical, May 2019 |
| Acenxion Biosystems | , | Website taken over Mar 2025 - Jul 2025 |
| Quidel | , | Renamed QuidelOrtho after Ortho Clinical Diagnostics acquisition |
| Median Technologies | Burlington , MA | Imaging Phenomics |
| Celon Pharma | Kielpin, Poland | Generics, Small Molecule |
| Abbott | Longford, Ireland | Diagnostics |
| NorthEast BioLab | Hamden, CT | Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. |
| Scarlet Therapeutics | Bristol, UK | Red blood cell-based therapeutics |
| Quixgen | , | Website gone, Aug 2019 - Dec 2020 |
| Keenova | Hazelwood, MO | Small Molecules |
| Zai Lab | Suzhou, China | Small Molecules |
| Epigene Labs | Paris, France | Data Integration Platform |
| Brickell Biotech | , | Renamed Fresh Tracks Therapeutics, Sep 2022 |
| Gennao Bio | , | Website down Apr 2025 - Sep 2025 |
| Ancile Pharmaceuticals | , | Acquired by Mera Pharmaceuticals, Jan 2003 |
| Alexis Biotech | , | Dissolved May 2015 |
| Project Outlier | Palo Alto, CA | Consulting- Project, Program, and Portfolio Leadership, Service Development, Business Process Transformation, Change Management |
| Oxitope Pharma | , | Merged with Arxx Therapeutics to become Calluna Pharma, Jan 2024 |
| EnsiliTech | Bristol, UK | Biologic Stabilization |
| TGA Sciences | , | Acquired by Absorption Systems, Dec 2017 |
| |
Amsterdam, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Proterris | , | Website gone Jun 2022, not registered in MA |
| Hologic | Londonderry, NH | Diagnostic, Imaging |
| Intellimedix | , | Company founder/employee all moved on |
| Fournier Pharma | , | Acquired by Solvay, 2006 |
| Anesiva | , | Bankrupt 2010 |
| Smithers | Akron, OH | Contract Research |
| Gene Codes | Ann Arbor, MI | DNA Sequencing Software |
| Mill Creek Life Sciences | Rochester, MN | Cell Culture Supplements |
| Shennon Biotechnologies | San Francisco, CA | Proprietary single cell platform to create more effective immunotherapies |
| Ilypsa | , | Bought by Amgen $420M Jun 2007 |
| Gylden Pharma | Abingdon, UK | Vaccines using purely synthetic components to activate T-cells of the immune system |
| Hospira | , | Acquired by Pfizer, Sep 2015 |
| Getinge | Rastatt, Germany | Medical Technology |
| Intelligent Therapeutics | La Jolla, CA | Antibodies and antibody-like molecules |
| Bioconnection Bv | Oss, Netherlands | Contract Development & Manufacturing |
| , | Acquired by Canoa, Aug 2019 | |
| Omneuron | , | Closed |
| Tensys Medical | , | Website gone Sep 2017 |
| Teon Therapeutics | Redwood City, CA | Small molecules focused on GPCR targets for oncology indications |
| Tolremo Therapeutics | Basel, Switzerland | Cancer Resistance Prevention |
| Actus Biotechnologies | , | Website gone, Subsidiary Websites also gone |
| Synentec | Elmshorn, Germany | Cell Imaging |
| Orum Therapeutics | Daejeon, Korea | Cell-Penetrating Antibodies |
| HYALE SURGICAL | , | Renamed Hyalex Orthopaedics, May 2017 |
| One Biosciences | Paris, France | Therapeutic target discovery using AI & Single Cell technologies |
| Delpharm | Reims, France | Contract Manufacturing |
| AbOliGo | Cambridge, UK | Antibody-oligo Conjugates |
| Synex Medical | Toronto, ON | Non-invasive Health Monitoring |
| Abselion | Cambridge, UK | Biologics Quantification |
| Moleculent | Solna, Sweden | Functional biology platform detecting cell-cell interactions |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| Cell Guidance Systems | St. Louis, MO | Life science research tools |
| Alteogen | Daejeon, Korea | Long-acting Bio-betters |
| Arroyo BioSciences | , | Gone Apr 2019; Not sure active, Dec 2016 |
| NuHigh Biotechnologies | Suzhou, China | PCR Reagents |
| EGEN | , | Acquired by Celsion, Jun 2014 |
| EcoSurg | , | Shut Down May 2017 |
| Epoch Biosciences | , | Acquired by Nanogen, Sep 2004 |
| Cascadia Life Sciences | , | Website gone Nov 2017 |
| Anwita Biosciences | San Carlos, CA | Antibodies & Fusion Proteins |
| , | Website down Nov 2025 - Mar 2026; LI gone Mar 2026 | |
| BioGX | Amsterdam, Netherlands | Molecular Diagnostics |
| SIWA Biotech | , | Website down Jan 2022 - Jul 2022 |
| Tyrosine Pharmaceuticals | , | Changed name to Zocere |
| Silence Therapeutics | Berlin, Germany | RNAi |
| Lowell Therapeutics | , | Acquired by AcelRx Pharmaceuticals, Jan 2022 |
| Allvivo Vascular | Lake Forest, CA | Medical device coating |
| ORIG3N | , | Renamed Seaport Diagnostics |
| Surgivisio | , | Renamed eCential Robotics, Jan 2021 |
| Biosettia | , | Website down Feb 2025 - Jul 2025 |
| Proteolix | , | Bought by Onyx Pharmaceuticals, Oct 2009, up to $851M |
| Ukko | Tel Aviv, Israel | Food Allergy Treatments |
| AbRegen | , | Website gone, Mar 2019 |
| Cytomatrix | , | Gone, Jun 2013 |
| BioMed Valley Discoveries | Kansas City, MO | Small Molecule, Biologics |
| CardioPep Pharma | , | Acquired by and converted to Cardiorentis |
| Getinge | Ankara, Turkey | Medical Technology |
| CML Biotech | Ernakulam Dist., India | Lab Consumables |
| Medexus Pharmaceuticals | Toronto, ON | Specialty Pharmaceuticals |
| Rheonix | , | Website down Jun 2025; CEO left mar 2024, still on website Dec 2024 |
| Charles River Laboratories | Incheon, Korea | Research Animal Models and Preclinical Research |
| Ascentage Pharma | Suzhou, China | Small molecule cancer therapeutics |
| Thermalin Diabetes | , | Became holding company for Theramlin |
| Phenomyx | , | Gone Jun 2019 |
| Nykode Therapeutics | Oslo, Norway | Therapeutic DNA Vaccine |
| Axcynsis Therapeutics | Singapore, Singapore | Antibody-X Conjugates |
| |
Farmingdale, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| , | No news Sep 2010 - Oct 2025 | |
| GY Highland Biotech | , | Website down Feb 2025 - Jun 2025 |
| ZipBio | Seattle, WA | Compact Proteins |
| TRACER Europe | Groningen, Netherlands | Imaging CRO |
| Cell Design Labs | , | Acquired by Gilead, Dec 2017, up to $567M |
| CSSi LifeSciences | , | Renamed Qnova LifeSciences, Apr 2025 |
| STC Biologics | Newton, MA | Services |
| Allucent | Cologne, Germany | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| CureGene | Shanghai, China | |
| Kodiak Sciences | Palo Alto, CA | Long acting retinal medicines |
| Cytospire Therapeutics | London, UK | Immune cell engagers |
| BioElectroMed | , | Merged with ThelioPulse & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Synthelabo | , | Formed in 1970 through merger of Laboratoires Dausse & Laboratoires Robert & Carrière |
| Inzen Therapeutics | , | Flagship merged it into Cygnal Therapeutics and renamed it Sonata Therapeutics |
| Delpharm | Milan, Italy | Contract Manufacturing |
| Diagnostic Robotics | Tel Aviv, Israel | AI-triage and clinical-predications platform |
| , | Acquired by Collate, Aug 2025 | |
| Axon Therapies | Santa Clara, CA | Catheter Ablation System for Heart Failure |
| Medley Pharmaceuticals | Mumbai, India | Generics, APIs |
| Oranssibio | Shanghai, China | Cell & Gene Therapy Services |
| StarFish Medical | Victoria, BC | Contract Medical Devices |
| Pryor Medical Devices | , | Now known as Prytime Medical |
| AmCell | , | Seems to have been subsumed into Miltenyi |
| Gemini Bio | West Sacramento, CA | Media, Cell Culture Products |
| Lumenis | Osaka, Japan | Energy-based medical treatments |
| Green Elephant Biotech | Gießen, Germany | Cell Culture or Cell & Gene Therapies |
| 4d Pharma | , | Bankrupt Jun 2022; Acquired by SPAC via Reverse Merger Oct 2020 |
| |
Rankweil, Austria | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| IBSS Biomed | Krakow, Poland | Probiotic, devices for women's health |
| Qynapse | Boston, MA | Imaging Analysis |
| Fibrocor Therapeutics | Toronto, ON | Small Molecule for Fibrosis |
| Kailos Genetics | Huntsville, AL | Genetic Testing |
| Scientific Bioprocessing | Pittsburgh, PA | Shake Flasks |
| Instapath | Houston , TX | Automated Digital Pathology |
| Epigenesis Pharmaceuticals | , | Gone |
| Innovize | St. Paul, MN | Medical Device Contract Manufacturing |
| Biologics Modular | , | Renamed CleanroomsUSA, Jan 2024 |
| Bioretec | Tampere, Finland | Bioresorbable Implants |
| 10xBio | , | One guy doesn't seem serious Aug 2025; Filings late Mar 2025; Residential address, Jul 2022 - Nov 2023 |
| Araim Pharmaceuticals | , | Website gone Jul 2022 - Oct 2022 |
| Trio Medicines | London, UK | Small Molecules, Biologics |
| Aegera Therapeutics | , | Acquired by PharmaScience, May 2011 |
| Makiz | , | Acquired by Stada, Aug 2007, €125M |
| Novilytic | West Lafayette, IN | Products for mAb titer and relative aggregate content during the manufacturing process |
| Fate Therapeutics | San Diego, CA | Stem Cell-Modulating Therapeutics |
| Cherokee Pharmaceuticals | , | Bought by Merck Aug 2010? |
| Vedanta Biosciences | Cambridge, MA | Therapies that modulate pathways of interaction between the human microbiome and the host immune system |
| Applaud Medical | , | Rebranded as Avvio Medical, Jun 2024 |
| ISA Pharmaceuticals | Oegstgeest, Netherlands | Synthetic therapeutic vaccines |
| Axiom Real-Time Metrics | , | Acquired by Sitero, Jul 2025 |
| Tendyne Holdings | , | Acquired by Abbott, Sep 2015, $225M |
| Erytech Pharma | , | Merged with Pherecydes, Jun 2023 renamed PHAXIAM Therapeutics |
| , | Website down Oct 2025 - Feb 2026 | |
| metabion | Planegg, Germany | Custom Oligos, PCR Reagents, Lab products |
| Rakuten Aspyrian Therapeutics | , | Renamed Rakuten Medical, Mar 2019 |
| Domainex | Essex, UK | Drug Discovery Services |
| BALT | Montmorency, France | Products for the interventional access and treatment of neurovascular diseases |
| Simtra BioPharma Solutions | Halle, Germany | Contract Fill/Finish, Lyophilization |
| Paradigm Genetics | , | Renamed Icoria, Aug 2004 |
| LogicBio Therapeutics | , | Acquired by AstraZeneca, Nov 2022, $68M |
| |
Boston, MA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| , | Website down Jan 2026; Acquired by bioMérieux, Jun 2025 | |
| Vivint Pharma | Hyderabad, India | Contract Formulations |
| Pathway Genomics | , | Renamed OmeCare |
| Alpha-9 Oncology | Vancouver, BC | Radiopharmaceuticals |
| IVERIC Bio | , | Acquired by Astellas, Jul 2023, $5.9B; fka Ophthotech |
| Parabilis Medicines | Cambridge, MA | Cell-penetrating miniproteins |
| Ocean Therapeutics | , | Shut down June 2013 |
| MolecuLight | Toronto, ON | Device for Detecting Wound Infection |
| DASI Simulations | Dublin, OH | Computational modeling for structural heart disease procedures |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| InnoCare | Shanghai, China | Cancer Treatments |
| Getein Biotech | Nanjing, China | Mpox Diagnostic |
| Teleflex Medical | Bad-Liebenzell, Germany | Surgical and Medical Devices |
| SonALAsense | Oakland, CA | ALA Sonodynamic Therapy for Glioblastoma |
| Celprogen | Huissen, Netherlands | Stem cell research and therapeutics products for regenerative medicine |
| Virax Biolabs | Lanarkshire, UK | Viral test Kits |
| Velicept Therapeutics | , | Trying to find a buyer for company/IP Dec 2020; Website down Jan 2021 - Apr 2021 |
| AxoSim | , | Renamed 28Bio, Jun 2025 |
| Fresenius Kabi | Friedburg, Germany | Contract Manufacturing |
| Forbes Medi-Tech | , | Renamed FMI holdings, got out of drug business |
| Histide | Schindellegi, Switzerland | Cell Recoding Molecules |
| DanDrit Biotechnology | , | Acquired Enochian Biopharma, Feb 2018, took name Enochian Biosciences |
| Scientia Vascular | West Valley City, UT | Catheters & Guidewires |
| NeoCura | Beijing, China | Personalized Vaccines |
| Olema Oncology | San Francisco, CA | CAR T brake |
| Aerin Medical | Mountain View, CA | Nasal Obstruction Relief Device |
| Panacela Labs | , | Website down, Jul 2023 - Dec 2023, LI gone Nov 2023 |
| Proxy Biomedical | , | Renamed Aran Biomedical |
| QLSF Biotherapeutics | South SF, CA | Immuno-oncology |
| ImmunOs Therapeutics | Schlieren, Switzerland | Immunotherapy |
| Energesis Pharmaceuticals | , | 12 years nothing past RD, Residential Address, Nov 2021 |
| Petra Pharma | , | Seems to have failed to get investment, 2020 |
| |
Stockholm, Sweden | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Freyr Solutions | Hyderabad, India | Regulatory Consulting |
| Ruthigen | , | Merged with Pulmatrix, Jun 2015. Renaming company Pulmatrix. |
| Aptinyx | , | Dissolved, May 2023; Successor to Naurex |
| NGeneBio | Seoul, Korea | NGS Diagnostics Software |
| InMed Pharmaceuticals | Vancouver, BC | Cannabinoids & Cannabinoid Database |
| Geneva Bioinformatics | , | Taken over by a Swiss Instutite |
| TheraCoat | , | Renamed UroGen Pharma |
| Atugen | , | Acquired by SR Pharma 2005 |
| Herax Life Science | Copenhagen, Denmark | Clinical, regulatory, medical affairs and validation |
| OMEICOS Therapeutics | Berlin, Germany | Small Molecules based on Omega-3 Fatty acid metabolites |
| GSK | Paris, France | Small Molecules, Vaccines, Biologics |
| Lorus Therapeutics | , | Changed name to Aptose Biosciences, Aug 2014 |
| Vanda Pharmaceuticals | Washington, DC | Small Molecules |
| Bio-Thera Solutions | Guangzhou, China | Biosimilars |
| Migenix | , | Changed to Biowest Pharmaceuticals Mar 2010 |
| Leo Lens Technology | , | Renamed MediPrint Ophthalmics, Jan 2021 |
| SOFAR surgical | , | Acquired by TransEnterix, Sep 2015, $100M |
| Akesis LLC | , | Bankrupt 2015 |
| o2h Discovery | Ahmedabad, India | Drug discovery services |
| Coherent Biopharma | Suzhou, China | Multi-Targeting Ligand Platform |
| Lycera | , | People who left in 2018 still on website Jan 2021. Everyone has another job. |
| Alzheon | Framingham, MA | Small Molecules targeting Alzheimer's |
| Kintara Therapeutics | , | Merged with TuHURA Biosciences, Oct 2024 took name; fka DelMar Pharmaceuticals |
| Radix Pharmaceuticals | , | No site, no info, SBIR, Jul 2015 |
| Alliant Pharmaceuticals | , | Acquired by Sciele Pharma, Jun 2007 |
| NaviGate Cardiac Structures | , | Website taken over Feb 2025; Inactive May 2023 |
| Monod Bio | Seattle, WA | Custom Diagnostic Biosensors |
| CureBiotech | , | Presumed gone |
| Powervision | , | Acquired by Alcon, Mar 2019, $285M |
| , | Acquired by Eclipsebio, Jan 2026 | |
| EKF Diagnostics | Boerne, TX | Diagnostics |
| Metrohm | Plainsboro, NJ | Lab Data Management Software |
| AUDIT MicroControls | Eatonton, GA | QC Materials |
| Vivo BioSciences | , | Acquired by LifeNet health, Nov 2016 |
| Aadi Bioscience | , | Renamed Whitehawk Therapeutics, Mar 2025 |
| Dextera Surgical | , | Bankrupt, Assets sold to Aesculap, Feb 2018 |
| Dompé | L'Aquila, Italy | Biologics, Small Molecules, OTC |
| Procyrion | Houston, TX | Minimally-invasive device for heart failure treatment |
| numares | Houston, TX | Clinical Diagnostics |
| Induce Biologics | Irvine, CA | Bone regenerative devices |
| Insight Medical Systems | , | Acquired by Enovis, Jul 2022 |
| Starna Therapeutics | Suzhou, China | mRNA vaccine, therapies |
| Collaborative Neuroscience Network | , | Website down Jul 2021 - Dec 2021 |
| Diaceutics | Belfast, UK | Diagnostics Services and Development |
| Orbital Therapeutics | Cambridge, MA | RNA technology (not RNAi) |
| Evidation Health | San Mateo , CA | Behavioral Data Collection |
| Cytiva | Piscataway, NJ | Medical Devices |
| Asymchem | Woburn, MA | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| Roivant Sciences | New York, NY | Alliances, Collabs, Partnerships |
| Angex Pharmaceuticals | , | Gone 2018 |
| Quiescence Technologies | , | Website Gone |
| Escend Pharmaceuticals | , | New business at address Feb 2025; Business filings late Mar 2023 - Feb 2025; co-located with Edison Oncology |
| Oncovalent Therapeutics | , | Shut down Feb 2024 |
| Silverline Biologics | , | Website suspended, Sep 2020 - Jan 2021 |
| Borean Pharma | , | Gone |
| Organon (2) | Jersey City, NJ | Women's Health |
| Ovation Diagnostics | , | Renamed New Day Diagnostics, Jan 2023 |
| RedHill Biopharma | Tel Aviv, Israel | Orally-administered, small molecule drugs for the treatment of inflammatory and gastrointestinal diseases, including cancer |
| Klocke Group | Fort Myers, FL | Contract Manufacturing |
| Ferrum Health | Sunnyvale, CA | Radiology AI platform |
| , | Acquired by Epitype, Oct 2025 | |
| Dante Labs | , | Seems to be Dante Genomics now |
| , | Main person has four other jobs, Dec 2025 | |
| Vadovations | , | No info. 2012 SBIR grant |
| Biomatters | , | Renamed Geneious |
| GenVec | , | Bought by Intrexon, Jun 2017, $16M in stock |
| Cell Kinetics | , | No website, Aug 2018, public shell |
| RubrYc Therapeutics | , | Website gone Nov 2022; Substantially all assets acquired by iBio, Sep 2022; spun out of HealthTell |
| Cytapex Bioinformatics | , | Acquired by Insightful Science, May 2020 |
| |
Columbia, MD | Grace | Supporting the pharmaceutical value chain with custom engineered silicas, chromatography resins, and multifunctional formulation excipients. U.S.-based CDMO with 2 integrated sites to support your next small molecule drug project. |
| Shire | , | Bought by Takeda, Jan 2019, $62B |
| Evopoint Biosciences | Jiangsu, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Heart Genomics | , | No info since 2013 as of Mar 2019, presumed inactive |
| Chatham Therapeutics | , | Acquired by Baxter, Apr 2014, $70M+ |
| |
Bristol, PA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Intellikine | , | Bought by Millennium 2011 |
| Ergomed | Madrid, Spain | Clinical Research |
| Atrium Therapeutics | San Diego, CA | RNA Therapies |
| Felix Biotechnology | , | Website gone Aug 2024; Linkedin page gone Jun 2024, CA business filings late Dec 2023 |
| Organix | Woburn, MA | Contract Research & Development |
| AssayQuant | Marlborough, MA | Fluorescence Microplate Assays |
| , | Website down Dec 2025 - Jun 2026; Was in Canada, CEO now in Texas Aug 2022 | |
| etectRx | Gainesville, FL | Clinical Trial Adherence Technology |
| dermadiagnostics | , | Renamed Curiva, Feb 2021 |
| Prime Biologics | , | Seems gone 2019 |
| Spotlight Therapeutics | , | Shut down Dec 2024 |
| Assembly Pharmaceuticals | , | Merged with Ventrus Biosciences, Jul 2014 to become Assembly Biosciences |
| Prodeon Medical | Sunnyvale, CA | BPH Implant Treatment |
| Epikardis Medical | , | Shut Down pre-Apr 2017 |
| Biolinq | San Diego, CA | Needle-Free Blood Glucose Monitoring |
| , | Website down Jan 2026 - May 2026; Acquired by Xoma, Aug 2025; Spun out of Alkermes Nov 2023 | |
| Biological Industries | , | Acquired by Sartorius, Dec 2019, $50M |
| BiOneCure Therapeutics | , | No employees on Linkedin, no updates Apr 2022 - Mar 2025 |
| One Lambda | , | Acquired by Thermo Fisher, Sep 2012 |
| , | Renamed Cordica Medical, Jan 2026 | |
| Ergomed | Belgrade, Serbia | Clinical Research |
| Nordic Bioscience | Herlev, Denmark | Biomarker extracellular matrix specialist |
| DiNAQOR | Laguna Hills, CA | Gene Therapy for Heart Conditions |
| Inotiv | Fort Collins, CO | Contract lab services, Scientific Instruments |
| Anoixis | Natick, MA | Pharmacometric Services |
| Baseclick | Neuried (near Munich), Germany | Click chemistry-based products and services for nucleic acid modification |
| Nucleome Therapeutics | Oxford, UK | Drugs targeting noncoding genes |
| Dfh pharma | , | No info Jun 2015, Oct 2016, Dec 2019 |
| Meribel Pharma Group | Hoganas, Sweden | Contract Manufacturing |
| |
Krakow, Poland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Boston Scientific | Marlborough, MA | Medical Devices |
| Calcilytix Therapeutics | , | Rolled into BridgeBio, Feb 2024 |
| Acacia Biosciences | , | Acquired by Rosetta Inpharmatics, Feb 1999 |
| Alembic Pharmaceuticals | Gujarat, India | Generics |
| Confo Therapeutics | Ghent, Belgium | GPCR targeted therapeutics |
| SigmaGraft | Fullerton, CA | Bone Substitute, Wound Dressing, Resorbable Membrane, Orthopedics |
| , | Website down Jun 2025 - Oct 2025 | |
| EpicentRx | La Jolla, CA | Epigenetics, Oncolytic viruses |
| Akshar Global Clinical Research | Dover, DE | Clinical Research Services |
| ClinPharm | , | Website down Apr 2025 - Sep 2025 |
| Magnet Biomedicine | Boston, MA | Molecular Glues |
| Selborne Biological Services | Hampshire, UK | Blood products, cell culture supplements, contract manufacturing, antibodies |
| Centric Medical | Huntley, IL | Surgical plates, screws, bone matrix, marrow harvesting |
| PAM Theragnostics | Hennigsdorf, Germany | Alzheimer's Theranostics |
| , | Acquired by Boston Scientific, Nov 2024, $3.7B | |
| Likang Life Sciences | Beijing, China | Cell Therapies, Genetically Engineered |
| UNDBIO | Gyeonggi, Korea | Insulin, Pumps, Contract Manufacturing |
| Akonni Biosystems | Frederick, MD | Lab Supplies & Reagents |
| PCI Pharma Services | Bridgewater, MA | Contract Manufacturing, Services |
| Advanced Pharmaceuticals | , | Website gone, Mar 2019 |
| Piramal | Lexington, KY | CDMO |
| Chase Therapeutics | , | Located on the Lobbying street in DC (K Street), no news 2018-2023 |
| UPM Pharmaceuticals | Bristol, TN | Formulation Development, Contract Manufacturing |
| , | Acquired by Fujirebio, 2022 | |
| Latham Biopharm Group | Cambridge, MA | Consulting |
| Telix Pharmaceuticals | Sydney, Australia | Radio immunotherapy |
| Vaximm | Mannheim, Germany | Attenuated bacterial therapy |
| ProPharma Group | Windsor, ON | Consulting |
| NanoVector | , | Gone 2019 |
| , | Website down Jun 2025 - Dec 2025 | |
| Victory Pharma | , | Assets Acquired by Shionogi |
| Angiogene Pharmaceuticals | , | Dissolved Jan 2017 |
| Mekonos | , | Bankrupt Jun 2024; Website down Oct 2024 |
| Skeletalis | Boston, MA | Osteoporosis Treatment |
| InnoCare | Nanjing, China | Cancer Treatments |
| Cordis | Miami Lakes, FL | Medical Devices |
| Vantiva Precision BioDevices | , | Website taken over by a logistics & vinyl record company |
| Axial Biotech | , | Closed Mar 2013 |
| , | Renamed KadisBio | |
| SmartBead Technologies | , | Merged with FingerPrint Diagnostics to become Pronostics |
| VivaVision Biotech | Shanghai, China | Small molecule for dry eye |
| MedImmune | , | Acquired by AstraZeneca, Apr 2007, $15.6B; folded into AstraZeneca, Feb 2019 |
| Aurion Biotech | Seattle, WA | Ocular Transplant Therapies |
| Selexis | , | Merged with KBI Bio by parent, May 2023; Purchased by JSR Life Sciences, Jul 2017 |
| Biosynth Carbosynth | , | Renamed Biosynth, Sep 2022 |
| CAMAG Scientific | Muttenz, Switzerland | Chromatography |
| Lindy Biosciences | Morrisville, NC | Novel Drug Formulations |
| Epirus Biopharmaceuticals | , | Chapter 7 bankruptcy, Jul 2016 |
| Mount Tam Biotechnologies | , | Acquired by an oil field service company; Website down Nov 2019 - Aug 2020; Went public via reverse merger with cigar maker |
| Intravacc | Bilthoven, Netherlands | Vaccine CDMO |
| Medpointe Pharmaceuticals | , | Acquired by Meda Aug 2007, $767M |
| Haupt Pharma | , | Merged with Aenova |
| Presbyopia Therapeutics | , | Renamed Lenz Therapeutics, Jun 2021 |
| SunGen Pharma | , | Renamed Praxgen Pharmaceuticals |
| Angeion | , | Renamed MGC Diagnostics, Aug 2012 |
| BioDuro-Sundia | , | Renamed BioDuro, Jan 2025 |
| Edimer Pharmaceuticals | , | Employees all gone. Website gone. |
| SnapGene | Boston, MA | Software for planning, visualizing, and documenting molecular biology procedures |
| Cerebral Therapeutics | , | Website down Dec 2024; LI page gone Jul 2024 |
| Alpha Catalyst Genomics | , | Renamed Watchmaker Genomics |
| Bafna | Chennai, India | Generics |
| RoslinCT | Edinburgh, UK | Stem Cells |
| Exsurco Medical | Wakeman, OH | Tissue removal, Surgical Device |
| Clip Health | , | Shut down Aug 2023 according to founders LI profiles; fka Luminostics |
| PlaSalus | , | Amateurish looking |
| , | Renamed WallabyPhenox | |
| Breath Therapeutics | , | Bought by Zambon, Jul 2019, $160M + $405 Milestones |
| CellPath Therapeutics | , | Company appears to be gone, Oct 2016 |
| Innova Biosciences | , | Folded into Expedeon, Mar 2018 |
| Levolta Pharmaceuticals | Doylestown, PA | Improved delivery |
| BioCis Pharma | , | Lx Therapies, May 2011 to become Laurantis Pharma |
| Spriggs Bioanalytical Consulting | , | Not registered in MA, Nov 2022 - Dec 2023 |
| ALK Abello | Round Rock, TX | Allergy Diagnostics, Treatments |
| Oncovista | , | Dormant 2016 |
| Leo Pharma | Ballerup, Denmark | Small Molecules |
| Abcellute | , | Dissolved, Sep 2016 |
| Sharp | Macungie, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| ImCare Biotech | Doyelstown, PA | Drugs, Diagnostics |
| Quad Five | Ryegate, MT | Production of high-quality animal blood and serum products |
| Pharmagen Laboratories | , | Website down Apr 2023 - Sep 2023 |
| Copley Scientific | Nottingham, UK | Test equipment |
| Acepodia | Alameda, CA | Antibody-Cell Conjugation Therapy |
| Immunochina | , | Website down Dec 2020 - May 2021 |
| BlueWhale Bio | Philadelphia, PA | Cell Therapy Manufacturing |
| Innolake Biopharm | Shanghai, China | Monoclonal Antibody, Antibody Drug Conjugate, Small Molecule |
| Dipharma | Kalamazoo, MI | APIs, Generics |
| mAbRx | , | Gone |
| Ablative Solutions | Wakefield, MA | Transcatheter Perivascular Denervation |
| PionEar Technologies | , | Shut down Dec 2023; Website down May 2024 - Jul 2024 |
| , | Acquired by Fidia Pharma, Sep 2025 | |
| Serendex Pharmaceuticals | , | Bought by Savara Pharmaceuticals, Jun 2016 |
| Periblation Medical | , | Renamed Nafas Medical, Mar 2016 |
| Cytovance Biologics | Oklahoma City, OK | Contract Biologics Development & Manufacturing |
| Abbisko Therapeutics | Shanghai, China | Immunomodulators for cancer |
| Emerald Health Pharmaceuticals | , | Website down Dec 2021 - Apr 2022 |
| Burning Rock Biotech | Guangzhou, China | Cancer Treatment |
| Pharmaron | Ningbo, China | R&D Services |
| OBDURO Biotechnologies | , | never a registered CA business |
| SurgRx | , | Acquired by Ethicon, Aug 2008 |
| LAgen Laboratories | , | Website down Dec 2023 - May 2024 |
| Medicure | Winnipeg, MB | Small Molecule |
| , | Website down Jul 2025 - Dec 2025 | |
| GNS Healthcare | , | Renamed AITIA, Jan 2023 |
| BioFluidica | Lawrence, KS | Liquid Biopsy |
| Global Access Diagnostics | Bedfordshire, UK | Rapid Immuno-Diagnostics |
| Emmecell | Menlo Park, CA | Cell Therapies for Ophthalmology |
| Key Biologics | , | Merged with Astarte Biologics, Aug 2018 |
| MabCo | , | Renamed Agenix |
| Serono Laboratories | , | Acquired by Merck KGaA, 2006 |
| Wincal BioPharm | South SF, CA | Eyedrop Formulation of Therapeutic Antibodies |
| Silvergate Pharmaceuticals | , | Acquired by cutisPharma, Jun 2019 |
| Virttu Biologics | , | Acquired by TNK Therapeutics, Apr 2017 |
| Turbine | Budapest, Hungary | Simulated cell technology for pharma r&d |
| Jubilant Clinsys | , | Folded in to Jubilant Life Sciences? Site disappeared, no info |
| Ontorii | , | Merged with Chiralgen to form WaVe Life Sciences |
| Peijia Medical | Suzhou, China | Transcatheter structural heart device and neurovascular devices |
| Eagle Pharmaceuticals | Woodcliff Lake, NJ | Repurposing Existing Drugs |
| BiosPacific | Emeryville, CA | Antibodies and antigens |
| Zephyrus Biosciences | , | Bought by biotechne, Mar 2016; Spun out of Berkeley |
| Novotech | Bangalore, India | Clinical Research |
| Ciphergen | , | Now Vermillion |
| ClinicalRM | , | Acquired by Icon plc, Sep 2016; aka Clinical Resource Management |
| Cirrus Biosciences | , | Shut Down Feb 2019 |
| Teleflex Medical | Vienna, Austria | Surgical and Medical Devices |
| Molecular Instruments | Los Angeles, CA | HCR RNA-FISH and immunofluorescence kits and protein imaging assays |
| , | Shut down Aug 2025 | |
| OncoLytika | Cambridge , UK | Technical Consultancy |
| Encysive Pharmaceuticals | , | Bought by Pfizer 2008; fka Texas Biotechnology Corp |
| Aria Pharmaceuticals | , | Shut Down Jan 2024; fka twoXAR Pharmaceuticals |
| NsGene | , | Website gone |
| Sagimet Biosciences | San Mateo, CA | Drugs targeting the fatty acid synthase enzyme |
| Paramune | San Carlos, CA | Biologic therapies for inflammatory diseases and cancer |
| Paradigm Diagnostics | , | Acquired by Exact Sciences, Mar 2020 |
| Maculogix | , | Assets Acquired by LumiThera Diagnostics |
| Tempered Biosciences | , | Absurd website has to be gone |
| DP Clinical | Rockville, MD | Clinical Research |
| GN Otometrics | , | Acquired by Natus, Jan 2017 |
| Worldwide Clinical Trials | San Antonio, TX | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| SSI Diagnostica | Hillerød, Denmark | Diagnostics |
| Igenomix | New Delhi, India | Contract genetic testing for reproductive health; covid-19 pcr |
| Sa-Ford | Navi Mumbai, India | Preclinical Contract Research |
| HAWK Biosystems | Derio, Spain | Microscope and Software for Cancer Sample Analysis |
| NextGen Jane | Oakland, CA | Menstrual Blood Diagnostics |
| OmniaBio | Hamilton, ON | Contract Manufacturing - Cells, Gene Therapy, Stem Cells |
| Genesis Imaging Services | , | Renamed Pharmanest |
| Ribocept | , | Defunct |
| , | Subsumed into Synoptics | |
| ActivMed Practices and Research | Portsmouth, NH | Clinical Research |
| Knopp Biosciences | , | |
| Sinomune Pharma | , | Website down Aug 2023 - Apr 2024 |
| Eurofins Genomics | Toronto, ON | Genomic Supplies & Services |
| Biomerics | Brooklyn Park, MN | Medical device design & manufacturing |
| Lavipharm | Paris, France | Small molecules |
| Cardiogen Sciences | , | Acquired by Audentes Therapeutics, Sep 2015 |
| Excite Pharma Services | Lee's Summit, MO | Analytical chemistry services, cGMP manufacturing and sterile fill services |
| Kirgen | Shanghai, China | Lab Supplies |
| Securecell | Urdorf, Switzerland | Lab automation |
| Valitacell | , | Acquired by Beckman Coulter, Sep 2022 |
| Amblyotech | , | Acquired by Novartis, Apr 2020 |
| Inovio Biomedical | , | Seems gone |
| Askgene Pharma | Camarillo, CA | Biosimilars |
| , | Website down Dec 2025 - Apr 2026 | |
| New Paradigm Biosciences | Acton, MA | Human immune system mice for antibody-drug discovery |
| Cyta Therapeutics | , | Shut down Aug 2025 |
| CelerDx | , | Tiny startup that went nowhere |
| Nuntius Therapeutics | London, UK | mRNA Therapies |
| Karo Bio | , | Renamed Karo Pharma |
| Paragon Genomics | Fremont, CA | Sequencing tools |
| Cardium Therapeutics | , | Now Taxus Caridium Pharmaceuticals |
| Resilience | Mississauga, ON | Biomanufacturing |
| Unigene Laboratories | , | Closed 2013 |
| Gene Signal | , | Bankrupt, Apr 2021 |
| Synexa Life Sciences | Leiden, Netherlands | Biomarker Services |
| Lydex Pharmaceuticals | , | Website down Jan 2024 - Jul 2024 |
| Pfizer | Surrey, UK | Consumer Healthcare |
| Polyrizon | Ra’anana, Israel | Nasal Drug Delivery |
| Aurigene Oncology | Bangalore, India | Drug discovery |
| Amherst Pharmaceuticals | , | Gone 2019 |
| StemAxon | , | Website Down May 2024 - Nov 2024 |
| Mediforum Pharmaceuticals | , | Website down Dec 2021 - Feb 2022 |
| Bash Biotech | San Diego, CA | Kidney, Neuro Treatments |
| Viridia Life Sciences | , | Website down Jan 2023 - Jul 2023 |
| Suraksha Diagnostic | Kolkata , India | Diagnostics |
| Arixa Pharmaceuticals | , | Acquired by Pfizer, Oct 2020 |
| Bioject | , | Assets acquired by Inovio, Mar 2016, $5.5M |
| Pangenetics | , | Bought by Abbott |
| Precipio Diagnostics | Omaha, NE | Oncology Diagnostics |
| Syncro Medical | Langhorne, PA | Software development |
| iXCells Biotechnologies | San Diego, CA | Cells, Reagents, Genomic Services |
| Ethicon | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Monroe Research | Monroe, NC | Clinical Trials |
| Polpharma Biologics | Amsterdam, Netherlands | Biosimilars |
| Janux Therapeutics | San Diego, CA | Immunotherapies for Cancer |
| Empatica | Milan, Italy | Seizure Detection |
| ActivMed Practices and Research | Methuen, MA | Clinical Research |
| Origin BioMed | , | Assets sold to Knight Therapeutics, Jun 2015 |
| Navitas Life Sciences | Bangalore, India | Decentralized Clinical Research, Consulting |
| , | Website down Dec 2025 - Feb 2026 | |
| Oncobit | Schlieren, Switzerland | Cancer Monitoring |
| Accuimage Diagnostics | , | Acquired by Merge eFilm, Jan 2005 |
| VectorBuilder | Guangzhou, China | Recombinant Vectors & Viruses |
| ScienCell Research Laboratories | Carlsbad, CA | Cells, Reagents, MolBio Supplies |
| Auris Health | , | Acquired by J&J, Apr 2019, $3.4B; fka Auris Surgical Robots |
| PolyProx Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| InnoN | Cheongju, Korea | Biologics, Small Molecules |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Dilyx Biotechnologies | , | Acquired by Soluble Therapeutics, Oct 2014 |
| T-Knife Therapeutics | Berlin, Germany | TCR Cell Therapies |
| NantPharma | , | Website down Mar 2023 - Sep 2023 |
| Axios Oncology | , | Not sure if active, doesn’t look serious from website, Oct 2018 |
| Maxim Biomedical | Rockville, MD | HIV Diagnostics |
| SEQENS | Devens, MA | Contract Pharmaceuticals |
| Metamark Genetics | , | Shut down 2018 |
| Proneuron Biotechnologies | , | Website not updated since 2009 |
| Perseo Pharma | Muttenz, Switzerland | Therapeutic Enzymes Delivery |
| , | Website down Jul 2025 - Dec 2025 | |
| SCHOTT Pharma | Mainz, Germany | Drug containment solutions and delivery systems for injectable drugs |
| Dream Pharma | , | Acquired by Alvogen $186M, Jun 2014 |
| Flexspark | , | Website down May 2023 - Sep 2023 |
| Alliances Catalyst | , | Liquidated |
| UBC | Overland Park, KS | Biopharmaceutical Consulting & Services |
| Cue Biopharma | Boston, MA | Immunotherapy |
| Glythera | , | Renamed Iksuda Therapeutics, Sep 2018 |
| Recodagen | , | Gone Jun 2009 |
| Accellacare | Mount Pleasant, SC | Clinical Research |
| Orphan Star Therapeutics | , | Intended to acquire drugs, 2019-2023 did not |
| Merrimack Pharmaceuticals | , | Laid everyone off, sold off assets May 2019. Attempting to survive long enough for milestones they're eligible for |
| Edison Pharmaceuticals | , | Renamed Bioelectron |
| |
Hombourg, France | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| , | Renamed Fathom Therapeutics, Apr 2026 | |
| Biomedical Research Models | , | Rebranded as Biomere, May 2016 |
| MakroCare | San Francisco, CA | Drug Development Partner |
| Empyrean Medical Systems | Boca Raton, FL | Radiotherapy Oncology System |
| PRI Research | , | Renamed Wake Clinical |
| , | Website down Oct 2025 - Jan 2026 | |
| Centerline Biomedical | Cleveland, OH | Surgical Navigation Technology |
| Confab Laboratories | , | Bought by Mylan, Jun 2016 |
| Mainstay Medical | Dublin, Ireland | Device for lower back pain |
| Novimmune | , | Rebranded as Light Chain Bioscience, Jul 2019 |
| Tenaya Therapeutics | South SF, CA | Cardiovascular Therapeutics |
| Alerchek | , | Closed late 2016 |
| Etern Biopharma | Shanghai, China | Condensate Targeting, Undruggable Proteins |
| Enovalife | Paris, France | Biometrics and medical writing services |
| Adamed | Czosnów , Poland | Small Molecules, Biologics |
| Delpharm | Quetigny, France | Contract Manufacturing |
| Epinoma | San Carlos, CA | Methyl-preserving amplification technology |
| Zyngenia | , | No news since 2013 as of Aug 2023 |
| Abbott | Des Plaines, IL | Diagnostics |
| Morphotek | , | Acquired by Eisai, Apr 2007 |
| ZenoBio | , | Website down Jan 2019-Feb 2019 |
| Cascadia Therapeutics | , | Merged with Antegrin Therapeutics to become Indalo Therapeutics, Oct 2016 |
| Tacalyx | Berlin, Germany | Antibodies for cancer |
| Ignis Therapeutics | Shanghai, China | |
| LeMaitre Vascular | Burlington, MA | Vascular surgical devices |
| Bristol Myers Squibb | Seattle, WA | Biologics |
| BioSpecifics | , | Acquired by Endo Pharmaceuticals, Dec 2020 |
| CD Diagnostics | Claymont, DE | Joint Pain Diagnosis |
| Juno Diagnostics | , | Shut down Jul 2023 |
| Xphyto Therapeutics | , | Renamed BioNxt Solutions, Nov 2022 |
| Amachumu Bio | , | Shut down April 2021 |
| Famy Life Sciences | , | Acquired by Viatris, Nov 2022 |
| CymaBay Therapeutics | , | Acquired by Gilead, Mar 2024, $4.3B |
| |
Shijiazhuang, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Inspire Medical Systems | Golden Valley, MN | Sleep Apnea Device |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Createrna Science | Wuhan, China | Small Molecules |
| Genta | , | Liquidation 2012 |
| HepaTx | Palo Alto, CA | Stem-Cell Based Liver Therapies |
| Ground Zero Pharmaceuticals | , | Website hijacked, Dec 2024 |
| Miltenyi Biotec | Bergisch Gladbach, Germany | Magnetic Cell Sorting Products |
| , | Acquired by Gilead, Apr 2026, $7.8B | |
| Biostar Pharmaceuticals | Beijing, China | Oncology Treatments |
| , | Website down Dec 2025 - Apr 2026 | |
| Golden Helix | Bozeman, MT | Genomic Data Management |
| Sorin | , | Merged with Cyberonics, renamed LivaNova, Oct 2015 |
| Diagnostic Photonics | , | Website down Aug 2023 - Dec 2023, no one at company |
| Introgen Therapeutics | , | Bankrupt 2008, executives reincarnated as MultiVir |
| KromaTiD | Boulder, CO | Biomarker discovery, genotoxicity and editing-associated errors assessment, plasmid manufacturing |
| Bovie Medical | , | Renamed Apyx Medical, Dec 2018 |
| Orbit Biomedical | , | Merged with Gyroscope Therapeutics, Apr 2019 |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Qrativ | , | Folded into nFerence |
| , | Acquired by NovAccess Global, Sep 2020; Unknown Modalities, Apr 2024 | |
| Impilo Therapeutics (1) | , | Acquired by CEND Therapeutics, Sep 2020 |
| , | Acquired by Sygnature Discovery, Aug 2023 | |
| Sanaria | Rockville, MD | Malaria Vaccine, Reagents for malaria research |
| Therorna | Beijing, China | RNA Therapies |
| Apitope | , | Acquired by Worg Pharmaceuticals, Aug 2021 |
| R/D Clinical Research | , | Website Gone |
| Alkensa Pharmaceuticals | , | Gone 2003 |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Enantigen Therapeutics | , | Acquired by OnCore Biopharma Oct 2014 |
| Alderley Analytical | Cheshire, UK | Bioanalytical Services |
| Cell-Easy | Toulouse, France | CDMO Cell Therapy Services |
| SiliCycle | Québec, QC | Separation Technologies |
| Evosep | Odense, Denmark | Automated Sample Prep |
| Zensun Sci & Tech | Shanghai, China | Biologics, Small Molecule |
| , | Dissolved Jun 2019 | |
| Revere Pharmaceuticals | , | Filings late Mar 2024 - Sep 2025; No news 2021 - Sep 2025; Residential Address, Aug 2022 - Aug 2025 |
| Argon Medical Devices | Plano, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Aramis Biotechnologies | Quebec City, QC | Plant Bioproduction |
| Chundsell Medical | , | Renamed Prostatype Genomics |
| RPRD Diagnostics | Milwaukee, WI | Pharmacogenetic Testing |
| Accela ChemBio | , | Website dangerous, Mar 2024 |
| Remedium Bio | Needham, MA | Gene Therapy |
| ImmPACT Bio | , | Acquired by Lyell Imunnopharma, Nov 2024; Merged with Kalthera, Jul 2021 |
| Aixial Group | Boulogne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| Pangaea Pharmaceuticals | , | Became Zycos |
| Dualogics | , | Platform acquired by AbCellera, Aug 2020 |
| PrimeVigilance | Surrey, UK | Pharmacovigilance Consulting |
| Aperio Clinical Outcomes | Durham, NC | Clinical development services |
| Inari Medical | Irvine, CA | Catheter-based technologies for the treatment of venous thromboembolism |
| Biocrede | Plymouth, MI | Catheters, PCR assays, RD services |
| Moximed | Fremont, CA | Joint treatment |
| BasePair Genomics | , | Renamed Incite Genomics, Oct 2023 |
| Canton Biologics | Guangzhou, China | CMC Development, GMP Manufacturing |
| Sfunga Therapeutics | , | Renamed Elion Therapeutics, early 2024? |
| Oxford Cancer Analytics | Toronto, ON | Liquid Biopsy |
| Xcyte | , | Merged with Cyclacel, Dec 2005 |
| Oriel Therapeutics | , | Bought by Sandoz, Jun 2010 |
| cellvie | Zurich, Switzerland | Therapeutic Mitochondria Transfer for Anti-Aging |
| Lipocine | Salt Lake City, UT | Drug Delivery |
| Lonza | Cologne, Germany | Contract Manufacturing, Development; Lab Systems, Research Products |
| Acerus Pharmaceuticals | , | Website down Dec 2023 - May 2024; fka Trimel Pharmaceuticals |
| 4C Pharma | Piscataway, NJ | Clinical Research Org |
| KBioSim | , | Website down Dec 2017-May 2018 |
| Intrafuse | , | Tech acquired by Conventus Orthopedics, Dec 2019 |
| Protagonist Therapeutics | Newark, CA | Oral peptides for GI indications |
| JD Bioscience | Gwangju, Korea | Small Molecules |
| Forbius | , | Acquired by BMS, Aug 2020; fka Armada Pharmaceuticals, fka Formation Biologics |
| PharmaLex | Munich, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Chantibody | Menlo Park, CA | Antibody discovery platform |
| Dendreon | Seal Beach, CA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Avitide | Lebanon, NH | Custom affinity purification discovery service |
| Progenika | , | Bought by Grifols |
| Slate Pharmaceuticals | , | Bought by Actient Pharmaceuticals Dec 2011 |
| Supernus Pharmaceuticals | Rockville, MD | Small Molecules |
| Sonrai Analytics | Belfast, UK | AI for scientific data analysis |
| Morphogenesis | , | Renamed TuHURA Biosciences, Dec 2023 |
| Gritstone Bio | , | Website down Feb 2025; Bankruptcy, Oct 2024; fka Gritstone Oncology |
| Paranta Biosciences | , | Website gone Dec 2021 |
| QuVA Pharma | Sugar Land, TX | Compounding Outsourcing |
| Sino Biological | Beijing, China | Reagent supplier and contract research organization. |
| MVP Laboratories | , | Acquired by Phibro Animal Health, Jan 2016 |
| Unither Pharmaceuticals | Amiens, France | CDMO |
| Convalesce | , | Website down Nov 2024 - May 2025 |
| Argon Medical Devices | Henrietta, NY | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| Facet Medical Technologies | Atlanta, GA | Medical Device Design & Development |
| Sensys Medical | , | Old company, no website, presumed defunct |
| STB Lifesaving Technologies | , | Website gone |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Ventris Medical | Newport Beach, CA | Tissues |
| TCG GreenChem | Ewing, NJ | |
| System Biosciences | Palo Alto, CA | Stem Cell & Biotechnology Supplies |
| Siren Biotechnology | San Francisco, CA | AAV Immuno-Gene Therapy |
| InnoVoyce | Boston, MA | ENT Lasers |
| Tulex Pharmaceuticals | Cranbury, NJ | Drug Delivery Technology |
| Ionis Pharmaceuticals | Carlsbad, CA | RNA |
| Genezen | Lexington, MA | Lentiviral & retroviral vector specialist, Genezen, offers early process development, GMP vector production, analytical testing & assay development. |
| Quick Biology | Monrovia, CA | Next-gen Sequencing Analysis |
| to-BBB | , | Bankrupt, but may have come back as BBB Therapeutics |
| GenSight Biologics | Paris, France | Ophthalmic Gene Therapy |
| iLab Solutions | , | Assets acquired by Agilent, Aug 2016 |
| Zhimeng Biopharma | Shanghai, China | Hep B & Neurological Indications |
| OrganaBio | South Miami, FL | Modular Cell and Gene Therapy Manufacturing |
| Calypso Medical Technologies | , | Acquired by Varian Medical Systems, Sep 2011, $10M |
| BLIRT | , | Acquired by Qiagen, May 2022 |
| AavantiBio | , | Acquired by Solid Biosciences, Dec 2022 |
| biotx | Potsdam, Germany | Causal Interference Modeling |
| Aortica | , | Acquired by Terumo, Nov 2019 |
| CF PharmTech | City of Industry, CA | Specialty Respiratory Pharmaceuticals |
| Aravis BioTech | , | No news Oct 2020 - Feb 2025 |
| Moon Surgical | San Carlos, CA | Robotic Surgery System |
| AL-S Pharma AG | , | New Dec 2016, no site Aug 2018 |
| MCG Pharma | Yenimahalle/Ankara, Turkey | Contract filling |
| ProCept Inc. | , | Switched business model from drugs to funeral services, 1999 |
| Tibotec Therapeutics | , | Bought by JnJ, now Janssen Therapeutics |
| Alkermes | Wilmington, OH | Small Molecules |
| Newcastle Resources | , | Renamed RepliCel Life Sciences |
| Biosion | Nanjing, China | Bispecific Antibody |
| Medrobotics | , | Bankrupt Jun 2022 |
| Assurance Scientific Laboratories | Birmingham, AL | Molecular Technologies |
| M.E. Pharmaceuticals | , | Website Gone, Sep 2015 |
| Ascendis Pharma | Heidelberg, Germany | Prodrug therapies |
| Daiichi Sankyo | Akita, Japan | Small Molecules |
| OptiMedica | , | Acquired by Abbott Aug 2013, $400M |
| BioFlo | , | Website down Oct 2022 - Mar 2023 |
| Avera Pharmaceuticals | , | Last record of employee being there on LinkedIn was 2010. Most left by 2007 it seems. |
| DiNAQOR | Hamburg, Germany | Gene Therapy for Heart Conditions |
| Sovereign Pharmaceuticals (2) | Fort Worth, TX | CDMO |
| NOVEX | , | Acquired by Thermo-Fisher, Aug 1999, stock |
| AurKa Pharma | , | Acquired by Lilly, May 2018 |
| Vivos Therapeutics | Littleton, CO | Oral appliance technology for sleep apnea |
| BlueReg | , | Acquired by Pharmalex, Nov 2022 |
| Angioblast Systems | , | Acquired by Mesoblast, May 2010 |
| , | Acquired by Siemens Healthineers, Apr 2021, $16.4B | |
| Cetazam Therapeutics | , | Renamed NeuroKappa Therapeutics |
| AdipoGenix | , | Gone Jun 2012 |
| Agilent | Winooski, VT | High-Throughput Screening Equipment, Imaging instruments |
| TCB | Heidelberg, Germany | Scalable Protein Production |
| Ardigen | Kraków, Poland | Ardigen accelerates therapy development by providing drug discovery services & AI platforms for biomedical imaging, microbiome and immunology research |
| AbbVie | Campoverde, Italy | Small Molecules, Biologics, Contract Manufacturing |
| SpePharm | , | Seems to be rolled into Norgine after started as a JV |
| Clover Therapeutics | , | Renamed Character Bio, May 2022 |
| Accellacare | Hickory, NC | Clinical Research |
| Parkure | , | Website down Jan 2024 - Jul 2024 |
| Piramal | Sellersville, PA | CDMO |
| Facio Therapies | , | Website down Oct 2022 - Mar 2023 |
| PhytoMedical | , | Apparently Gone |
| TxCell | , | Bought by Sangamo, Oct 2018, $84M |
| Stemetix | , | Shut down Apr 2021 |
| PDC Biotech | Epalinges, Switzerland | Nanomedicines |
| BDD Pharma | Glasgow, UK | Development and clinical testing of innovative pharmaceutical products. |
| Idience | San Francisco, CA | Cancer Therapies |
| Puresyn | Malvern, PA | Plasmid and Adenovirus Purification |
| CordenPharma | Chenôve, France | Contract Small Molecules |
| Pique Therapeutics | , | Shut down Dec 2020 |
| NewcelX | Nes-Ziona, Israel | Diabetes Treatment |
| , | Acquired by QOL Medical, Nov 2025 | |
| caprotec bioanalytics | , | Company or Technology Acquired by Charles River |
| Orbis Biosciences | , | Acquired by Adare Pharmaceuticals, May 2020 |
| iNanoBio | Scottsdale, AZ | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| Cache DNA | San Carlos, CA | Biomolecule Preservation |
| NextPharma | London, UK | Contract Research & Development |
| Targenics | , | No website Mar 2020 |
| Shape Therapeutics | Seattle, WA | RNA-editing gene therapy |
| American Stem Cell | , | Changed name to Targazyme |
| Clintrax Global | , | Acquired by WCG, Mar 2016 |
| Alcedis | Giessen, Germany | Clinical Trial Services |
| Iroko Pharmaceuticals | , | Sold off products Feb 2019, not sure what they're doing, website gone |
| Vivolux | , | Website down Aug 2023 - Feb 2024 |
| Avila Therapeutics | , | Bought by Celgene, Jan 2012, $350M |
| Obsidio | , | Acquired by Boston Scientific, Aug 2022 |
| AgileBio | le Kremlin-Bicêtre, France | IT Life Science Solutions |
| GE Healthcare | , | Acquired by Danaher, Apr 2020, $21.4B, rebranded as Cytiva |
| CORESTEM | , | Website down Jan 2024 - Sep 2024 |
| CallistoGen | , | Assets acquired by The Genetics Company, Mar 2003 |
| Argus Pharmaceuticals | , | Website down Apr 2019 - Jun 2019 |
| Enzolytics | , | Website down, Sep 2025; Seemed worthless, then became meme stock in early 2021, then became worthless again |
| Astek Diagnostics | Halethorpe, MD | UTI Diagnostic |
| Apellis Pharmaceuticals | Waltham, MA | Cyclic peptide analog |
| Zephyrm Bioscience | Beijing, China | Cell Therapy |
| fka NCS America | , | Renamed Alyve Medical, Apr 2022 |
| AMCR institute | , | Website down Jan 2018-Feb 2019 |
| Laboratoires Théa | Clermont Ferrand, France | Eye-care Products |
| Alexion Pharmaceuticals | , | Acquired by AstraZeneca, Jul 2021, $39B |
| ADAMAS Consulting | Surrey, UK | Regulatory Consulting |
| Feromics | Boston, MA | AI Immunotherapy Discovery |
| ChemoCentryx | , | Acquired by Amgen, $3.7B, Oct 2022 |
| Tanner Pharma Group | Cham, Switzerland | International Commercialization Services |
| Dongkoo Bio & Pharma | Seoul, Korea | Small Molecules, Contract Manufacturing |
| Zyga Technology | , | Acquired by RTI Surgical, Jan 2018 |
| Blackfynn | , | Gone Apr 2022 |
| Hexagon Bio | Menlo Park, CA | Fungal Genomic Sequencing, Possible Therapeutic Applications |
| Suvoda | Conshohocken, PA | Clinical Trial Software |
| IMS Health | , | Merged with Quintiles, May 2016 |
| Argon Medical Devices | Athens, TX | Guidewires, thrombus management, dialysis and vascular tools, drainage catheters and bone and soft tissue biopsy needles |
| icotec | Altstätten, Switzerland | Spinal Implants |
| Glaxo Wellcome | , | Merged with Smithkline Beecham in 2000 to form GSK |
| Presbyopia Therapies | , | Renamed Lenz Therapeutics, Jun 2021 |
| Ribometrix | Durham, NC | Small molecule drugs that target functional 3D RNA structures to treat human diseases. |
| Teva | Macquarie Park, Australia | Antibody Therapeutics |
| Eremid Genomic Services | Kannapolis, NC | Genomics & Bioinformatics Services |
| Cleave Therapeutics | , | Shut down Jul 2023 |
| Nuvisan Pharma Services | Neu-Ulm, Germany | Contract Research & Development |
| KPS Life Sciences | Malvern, PA | Clinical Research Services |
| Vitruvian Biomedical | , | No news Oct 2017 - Apr 2024; LI gone Nov 2023 |
| Norgine | Rueil-Malmasion, France | Specialty Pharma |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Elpen Pharmaceutical | Athens, Greece | Small Molecules, Generics |
| Bloomsbury Genetic Therapies | , | Shut down May 2025 |
| H-Immune Therapeutics | , | Acquired by HiFiBiO, Oct 2018 |
| , | Website down May 2025 - Dec 2025 | |
| Ceptyr | , | Out of business 2012 |
| Urigen Pharmaceuticals | , | Renamed Vantelix, Feb 2023 |
| Spherix | , | Renamed Alkido Pharma, Mar 2020 |
| LPixel | Tokyo, Japan | Image Analysis Technology |
| NOMIR Medical Technologies | , | Shut Down Jun 2014 |
| Targovax | , | Renamed Circio, Apr 2023 |
| Verity BioConsulting | , | Seems gone, owner has about 3 other jobs and five board positions |
| Alphazyme | , | Acquired by Maravai Life Sciences, Jan 2023 |
| Yuhao Chemical | Hangzhou, China | Chemical Products |
| Lead Pharma | Deventer, Netherlands | Small Molecules |
| Alsius | , | Assets purchased by Zoll Medical, May 2009, $12M |
| NK CellTech | Shanghai, China | Cell Therapies |
| Boster Bio | Pleasanton, CA | Antibodies, ELISA kits, etc. |
| Micromet | , | Bought by Amgen Jan 2012, $1.2B |
| SoniTrack Systems | , | Acquired by Zimmer Biomet, Jun 2016 |
| BYOMass | Sudbury, MA | Metabolic Therapies |
| Vascular Dynamics | , | Website down Dec 2024 - May 2025; Business filing late Oct 2024 |
| Kiyatec | Greenville, SC | ex vivo 3D cell culture technology |
| SmaBio Labs | Durham, NC | Contract Research Organization specializing in Chemistry Manufacturing and Control |
| StageBio | Mount Jackson, VA | GLP-compliant research, preclinical and clinical histology, pathology and specimen archiving |
| Masimo | Irvine, CA | Noninvasive patient monitoring |
| VIRxSYS | , | Ran out of money, closed down 2012 |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Ossis | , | 3D-printed orthopedic implants |
| FlashCell | , | Merged with Vectalys, May 2018, became Flash Therapeutics |
| Nizyme | , | Gone Jul 2015 |
| HRA Pharma | , | Acquired by Perrigo, May 2022, $2.1B |
| Heligenics | Las Vegas, NV | Cell-Based Genetic Variant Libraries |
| Illumina | Hayward, CA | Genomic tools, research products, molecular diagnostics, NGS |
| PharmEnable Therapeutics | Cambridge, UK | AI Drug Discovery platform |
| Fore Biotherapeutics | Philadelphia, PA | BRAF-Inhibitors, In-licensing others |
| Pharma Consulting Group | , | Website down Jun 2020 - Oct 2020 |
| Butterfly Network | Palo Alto, CA | Subscription Ultrasound Device |
| Concentric Analgesics | San Francisco, CA | Drug discovery & development |
| Siemens Healthineers | Norwood, MA | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Bio Genuine Biotech | Beijing, China | Small Molecules |
| Jubilant HollisterStier | Montreal, QC | Contract manufacturer specializing in sterile injectable fill finish, ophthalmics, topicals, ointments, and ampoules |
| ImmunArray | , | Shut Down, 2021 |
| Covalution Biosciences | , | Merged with Aspire Therapeutics to become Acerta Pharma |
| ABK Biomedical | Halifax, NS | Embolization Microspheres for Imaging |
| Integromics | , | Bought by Perkin-Elmer 2017 |
| Agere Pharmaceuticals | , | Acquired by Patheon, Mar 2015 |
| EG-Gilero | , | Renamed Gilero, Oct 2019 |
| Cognate Therapeutics | , | Now Cognate Bioservices |
| In2cure | , | Website down Dec 2022 - Apr 2023 |
| , | Renamed Numerion Labs, Oct 2025 | |
| Amarillo Biosciences | , | Renamed Ainos Apr 2021; Emerged from Bankruptcy, May 2015 |
| ETHICAL ONCOLOGY SCIENCE | , | Acquired by Clovis Oncology, Nov 2013 |
| NeuroRx | , | Renamed NRx Pharmaceuticals |
| LISI MEDICAL | Neyron, France | Subcontractor of implants and medical instruments |
| Proteona | , | Acquired by Singleron, Mar 2022 |
| Micropore Technologies | Morrisville, NC | Membrane-Based Process Equipment |
| Viant Medical | South Plainfield, NJ | Contract Medical Devices |
| vivoPharm | , | Acquired by Cancer Genetics, Aug 2017, $12M |
| Chembiotek Research International | , | Renamed TGC Lifesciences |
| Rosedale Medical | , | Now Intuity Medical |
| , | Website down Jan 2026 - May 2026 | |
| Engine Biosciences | Singapore, Singapore | AI & genomics |
| BreezeBio | Brisbane, CA | Nonviral CRISPR-delivery system |
| Ovid Therapeutics | New York, NY | Treatments for rare brain disorders |
| Studylog | South SF, CA | Animal Study Workflow Software |
| TE Connectivity | Schaffhausen, Switzerland | Medical Devices |
| Biota Holdings | , | Merged with Nabi pharmaceuticals to become Biota Pharmaceuticals, Nov 2012 |
| Convoy Therapeutics | , | Website gone, Feb 2015, tech/assets sold to CTX |
| Advanced Inhalation Research | , | Acquired by Alkermes, Feb 1999 |
| Celltrion | Incheon, Korea | Monoclonal Antibody Biosimilars |
| Aldevron | Fargo, ND | High-quality plasmid DNA, proteins, enzymes, antibodies, and other biologicals |
| Adaptive Phage Therapeutics | , | Acquired by BiomX, Mar 2024 |
| , | Acquired by Johnson & Johnson, Oct 2024, $600M + $1.1B milestones | |
| Shorla Oncology | Clonmel, Ireland | Cancer Treatments, 505(b)(2) |
| Gotect Diagnostic | , | Website only in Hebrew, Aug 2019, gone Aug 2021 |
| Voitheia Bioscience | , | |
| Wound Care Technologies | , | Employees all gone Sep 2022 |
| OMNILife Sciences | , | Acquired by Corin Group, Mar 2019 |
| Synarc | , | Merged with Bioclinica Mar 2014 |
| Nexa Orthopedics | , | Acquired by Tornier, Feb 2007 |
| Amarex Clinical Research | Germantown, MD | Clinical Research |
| Leadhexa Biotechnologies | , | Business lapsed, 2015 |
| |
Cambridge, UK | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Emosis Diagnostics | , | Website down Nov 2023 - Mar 2024 |
| CD Genomics | Shirley, NY | Genomics Services |
| Specific Diagnostics | , | Acquire by bioMérieux, May 2022 |
| Concerto Biosciences | Cambridge, MA | Bacterial Skin Therapies |
| Cellectis | Paris, France | Genetic 'Surgery' Therapeutics |
| preclinics | Parma, Italy | Contract Research |
| Bolt Biotherapeutics | Redwood City, CA | Systemically delivered Immune-Stimulating Antibody Conjugates |
| Spyre Therapeutics | Waltham, MA | Antibodies |
| Revascular Therapeutics | , | Acquired by Boston Scientific, Feb 2011 |
| Hongene Biotech Corporation | Union City, CA | Research chemicals, nucleic acids |
| Alkermes | Dublin, Ireland | Small Molecules |
| KV Pharmaceutical | , | Renamed Lumara Health out of bankruptcy, 2014 |
| Altor Bioscience | , | Bought by NantCell, Aug 2017, $360M |
| SightLife Surgical | , | Renamed CorneaGen, Apr 2018 |
| , | Acquired by Bora CDMO, Oct 2022 | |
| Bio-Concept Laboratories | , | Acquired by Pace Analytical, Dec 2020 |
| Captor Therapeutics | Wrocław, Poland | Targeted Protein Degradation |
| Extract Technology | Mauston, WI | Containment Equipment |
| Vincere Biosciences | Cambridge, MA | Small Molecules to Target Parkinson's |
| Cambrex | Paullo, Italy | Small Molecules Research, Development & Manufacturing Services |
| TeDan Surgical Innovations | Sugar Land, TX | Surgical Access Systems |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Lotte Biologics | Seoul, Korea | Biologics CDMO |
| Acuamark Diagnostics | New York, NY | Blood-based Cancer Detection |
| , | Website down Nov 2025 - Mar 2026 | |
| Eitan Medical | Netanya , Israel | Wearable Drug Delivery Devices |
| Preclin Biosystems | Epalinges, Switzerland | In vivo preclinical testing platform |
| Cabernet Pharmaceuticals | , | Gone 2021 |
| Humabs BioMed | , | Bought by Vir Biotechnology, Aug 2017 |
| Bioiberica | Barcelona, Spain | Heparin science, healthcare, companion animal health, animal nutrition, plant health |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Brainbits | , | Acquired by Transnetyx, Feb 2021 |
| Adare Pharma Solutions | Milan, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Oroboros Bio | , | Renamed Orna Therapeutics |
| Actuated Medical | Bellefonte, PA | Tubing Systems, Motors, Devices |
| Septerna | South SF, CA | GPCR Drug Discovery |
| Ipsen | Dreaux, France | Small Molecules, Biologics |
| Roche | Monza, Italy | Small Molecules & Diagnostics |
| MinInvasive | , | Website Down Jan 2022 - Jul 2022 |
| AriZeke Pharmaceuticals | , | Gone 2005 |
| Pelican Life Sciences | , | Sounds like they bought Biotix, then renamed themselves Biotix Holdings, but I really have no idea what happened here |
| Dharmacon | , | Bought by Horizon Discovery, Jul7 2017, $85M |
| Apollo Scientific | Manchester, UK | Research Products |
| Luna Diabetes | San Diego, CA | Insulin Pump |
| Droice | New York, NY | AI Clinical Data |
| Zhejiang Medicine | Shaoxing, China | Generics |
| Expansion Therapeutics | Waltham, MA | Small Molecules for RNA-mediated Diseases |
| Eupraxia Pharmaceuticals | Victoria, BC | Drug Delivery Technology |
| Stealth BioTherapeutics | Needham, MA | Mitochondrial disease therapies |
| AbD Serotec | , | Acquired from MorphoSys by Bio-Rad, Jan 2013, €53M |
| Zelegent | , | Website down Aug 2021 - Sep 2021; fka Snorx |
| Mycrodose Therapeutics | , | Website down Jun 2023 - Nov 2023; Founder gone Nov 2022 |
| AG Mednet | Boston, MA | Clinical Data Solutions |
| Alexza Pharmaceuticals | , | Acquired by Gruppo Ferrer, Jun 2016 |
| Pharmadax | New Taipei City, Taiwan | Generics |
| ONWARD Medical | Eindhoven, Netherlands | ARCex non-invasive spinal cord stimulation |
| Impopharma | , | Acquired by Rubicon Research, Jan 2020 |
| RS Research | Lausanne, Switzerland | Nanocarriers |
| Rilas Technologies | Woburn, MA | Purification & Analytical Solutions |
| Avenda Health | Culver City, CA | Prostate Tissue Ablation |
| Advanced Protein Technology | , | Different company operating at location, dated website, no employees on LinkedIn |
| La Jolla Nanomedical | , | Business filings late Aug 2022 |
| Theralink Technologies | , | Website down Nov 2024 - Apr 2025 |
| ARGO Medical Technologies | , | Renamed ReWalk Robotics, Oct 2014 |
| VClinBio | , | Acquired Cellix and now operating under that name it seems, Jan 2019 |
| Osivax | Lyon, France | Universal Flu Vaccine |
| Qynapse | Paris, France | Imaging Analysis |
| PolyActiva | Notting Hill, Australia | Drug-polymer conjugate technology, implants |
| DiscernDx | , | Website down Nov 2024; business filings late Jan 2024 |
| , | Acquired by Wacker, May 2023; Kartesia bought 100% of stock Mar 2021 | |
| Vedere Bio | , | Renamed Vedere Bio II ayfter most assets acquired by Novartis, Oct 2020, $150M + $130M Milestones |
| G Biosciences | St. Louis, MO | Research Tools & Reagents |
| Talaris Therapeutics | , | Merged with Tourmaline Bio, Oct 2023; fka Regenerex |
| Rona Therapeutics | Shanghai, China | RNA Therapeutics Platform |
| Optherion | , | Sold Assets, Still Exists |
| SYNkinase | , | Shut down |
| Invenra | Madison, WI | Antibodies and their derivatives |
| ValtedSeq | Gaithersburg, MD | Sequencing Data |
| Cedarburg Hauser Pharmaceuticals | , | Acquired by AMRI, Mar 2014 |
| Sintact Medical Systems | , | Seems gone, Sep 2021 |
| HAYA Therapeutics | San Diego, CA | RNA-based, RNA-targeting Fibrotic Therapies |
| Enigma Diagnostics | , | Liquidating, Apr 2017 |
| Koek Biotechnology | , | Renamed Hillal Biotechnology, Mar 2023 |
| Claret Medical | , | Acquired by Boston Scientific, Jul 2018, $220M + milestone |
| Circulomics | , | Acquired by Pacific Biosciences, Aug 2021 |
| Clariance Spinevision | Beaurains, France | Spinal Surgery Devices |
| Johnson and Johnson Innovative Medicine | Titusville, NJ | Small Molecules, Biologics |
| Atavistik Bio | Cambridge, MA | High-throughput screening platform to identify allosteric modulators of proteins |
| Aspivix | Epalinges, Switzerland | Tenaculum alternative |
| Dart NeuroScience | , | Closed down, Feb 2018 |
| Sesen Bio | , | Merged with Carisma Therapeutics, Mar 2023; fka Eleven Biotherapeutics |
| Origin Sciences | Cambridge, UK | Rectal/stool-sampling device |
| Almen Laboratories | , | Dissolved, Jan 2016 |
| Baili Pharmaceutical | Chengdu, China | Small Molecules, Biologics, Antibody Therapy |
| NoviSystems | , | Website down Jan 2023 - Jul 2023 |
| Specifica | Santa Fe, NM | Antibody discovery, libraries and affinity maturation |
| Sentrx | , | Bought by Telerx, Apr 2013 |
| AbbVie | Ludwigshafen am Rhein, Germany | Small Molecules, Contract Manufacturing |
| EnteroMedics | , | Acquired ReShape Medical, Oct 2017, renamed ReShape Life Sciences |
| NormOxys | , | Gone |
| NovalGen | Northwood Hills, UK | Bispecific Antibody-derived Cancer Therapies |
| Resonance Medicine | , | Shut down Dec 2023; No website Apr 2023 - Nov 2023; Not registered in CA May 2023 |
| Acusphere | , | Website gone, CEO gone, Nov 2015, Shell Company |
| Vivacitas Oncology | , | Business filings Late, Sep 2022 - Feb 2025, no real employees on LI |
| ReadyCell | , | Acquired by MedTech Barcelona, Nov 2024 |
| Primevera Therapeutics | , | |
| BillionToOne | Menlo Park, CA | Prenatal Genetic Testing |
| Celogos | , | No website Jan 2020 - Aug 2021 (founded 2001) |
| VictoGen | Irvine, CA | Analytical, Formulation Development, Regulatory |
| Oxitec | , | Bought by Intrexon, Aug 2015, $160M |
| RaySearch Laboratories | Shanghai, China | Cancer Research Software |
| Curegenix | , | Website down May 2021 - Oct 2021 |
| Advent Pharmaceuticals | , | Renamed VIP Pharma, Feb 2019, website gone |
| MagForce | , | Website down Apr 2023 - Sep 2023 |
| Atactic Technologies | , | Website copyright 2011 as of May 2019 |
| Evergen | Eden Prairie, MN | Comprehensive portfolio of allograft and xenograft biomaterials |
| SDC | Tempe, AZ | Clinical Data Services, Virtual Trials |
| Biomodal | Cambridge, UK | DNA methylation analysis kits |
| Osteologix | , | Liquidated, Sep 2015 |
| Avenge Bio | , | Shut Down Jul 2024 |
| Genos | , | Acquired by NantOmics, Apr 2017 |
| |
Kirchberg, Switzerland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Spear Bio | Woburn, MA | Immunoassays |
| NeuroVigil | Moffett Field, CA | Brain-wave reading technology |
| SHL Medical | Stockholm, Sweden | Medical Device assembly, labeling, packaging |
| Acton Pharmaceuticals | , | Acquired by Meda, Aug 2013 |
| Fluidigm | , | Renamed Standard BioTools, Jan 2022 |
| VuEssence | Odessa, FL | Molecular Diagnostics |
| Isofol Medical | Gothenburg, Sweden | Arfolitixorin |
| Nanyang Biologics | Singapore, Singapore | Natural Bioactive Compounds |
| CPTx | Planegg, Germany | Gene-encoding single-stranded DNA |
| Prism Pharmaceuticals | , | Acquired by Baxter 2011 |
| Brighter Ideas Inc | , | Website Gone, Mar 2017 |
| , | Website down Oct 2025 - Feb 2026 | |
| Douglas Pharmaceuticals | Auckland , New Zealand | Contract Manufacturing, Generics |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Sciex | Framingham, MA | Mass Spectrometers and Training |
| SAMDI Tech | , | Acquired by Charles River, Jan 2023, $40M |
| GeneCentric Diagnostics | , | Renamed GeneCentric Therapeutics, 2018? |
| Naked Biome | , | Website down Mar 2021 - Aug 2021 |
| S-Clinica | Brussels, Belgium | Clinical Supply Forecasting |
| AbSci | Vancouver, WA | E. Coli expression system for protein production |
| ThelioPulse | , | Merged with BioElectroMed & NanoBlate to become Pulse Biomedical, Nov 2014 |
| Trinity Drug Partners | , | Gone |
| MD Biosciences | , | Acquired by MLM Medical Labs |
| Platypus Technologies | Madison, WI | Cell-Based Assays |
| Norwich Pharmaceuticals | , | Folded into parent Alvogen |
| BZL Biologics | , | Gone 2003 |
| DeepBiome Therapeutics | , | Website redirecting Dec 2023 - May 2024 |
| Vyne Therapeutics | Bridgewater, NJ | Small Molecule |
| Digital Proteomics | , | Renamed Abterra Biosciences, Aug 2021 |
| Inventys | Mumbai, India | Contract Manufacturing APIs |
| Arcis Biotechnology | , | Liqudiating Jan 2023 |
| iotaSciences | Oxford, UK | Single-Cell Handling |
| Breathometer | , | Product didn’t work, pivoted |
| Latent Labs | San Francisco, CA | AI models to design and optimize proteins |
| Claritas Genomics | , | Closed Jan 2018 |
| Stellar Biotechnologies | , | Acquired/Merged with Edesa Biotech, Jun 2019 |
| Federation Bio | , | Assets acquired by Kanvas Biosciences, Oct 2023 |
| MedDay Pharmaceuticals | , | Failed Phase 3 Mar 2020, website gone Jan 2021 |
| Montis Biosciences | Leuven, Belgium | Immuno-oncology Antibody Therapies |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| Aelan Cell Technologies | San Francisco, CA | Stem Cell Technology |
| Arrowhead Pharmaceuticals | San Diego, CA | RNAi |
| Catalent | St. Petersburg, FL | Gelatin Capsule Manufacturing |
| PanTera | Mol, Belgium | Radiopharmaceuticals |
| Silabe | Niederhausbergen, France | Nonhuman primate products |
| Single Cell Technology | San Jose, CA | Antibody Discovery Platform |
| Innovative Metabolics | , | Renamed SetPoint Medical, Jul 2008 |
| Marin Biologic Laboratories | Novato, CA | Contract Services |
| Demegen | , | Terrible website from 2013 as of Dec 2019. Presumed Defunct. |
| ForSight VISION4 | , | Acquired by Roche, Jan 2017 |
| Rgenta Therapeutics | Woburn, MA | RNA-targeting medicines |
| CollabRx | , | Merged with Medytox Solutions, became subsidiary of Rennova Health Nov 2015 |
| , | Acquired by Bruker, May 2024, $393M; Chapter 11 bankruptcy, Jan 2024 | |
| Akashi Therapeutics | , | No annual report filed after 2018 as of Jul 2021; only employee on LI is a housekeeper; fka DART Therapeutics |
| Jouvenal | , | Bought by Warner-Lambert, 1997 |
| Autolus Therapeutics | London, UK | CAR-T cell therapy |
| Avisa Diagnostics | , | Renamed Allora Diagnostics, Oct 2022 |
| Boston Genetics | , | Acquired by Genomenon, Jun 2023 |
| Fluicell | Mölndal, Sweden | Tissue Production Platform |
| Entropia Biosciences | , | Shut Down June 2019 |
| BeneVir Biopharm | , | Acquired by J&J, May 2018, $140M + $900M milestones |
| Cambridge Endoscopic Devices | , | Bankrupt Sep 2015, selling assets off |
| Meilleur Technologies | , | Acquired by Lantheus, Jul 2024 |
| La Jolla Biologics | , | Website gone Nov 2014 |
| CDD | , | Acquired by Biofocus, Jun 2001 |
| AuramerBio | , | Website taken over Sep 2021 - Jan 2022 |
| Recon Therapeutics | , | Shut down Jun 2017 |
| Implen | Westlake Village, CA | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Exagen Diagnostics | Vista, CA | Diagnostics |
| Twistnostics | , | Renamed Scanogen |
| Cambria Biosciences | , | Gone Feb 2008 |
| , | Seems gone, Feb 2026 | |
| Annam Biosciences | , | Business filings late Dec 2023, CEO has additional jobs; Probably hoping someone buys tech, not especially active doesn’t seem Jan 2019 |
| Pace | Minneapolis, MN | Analytical Testing, CDMO |
| Guilford Pharmaceuticals | , | Bought by MGI Pharma, Jul 2005 |
| Structure Therapeutics | Shanghai, China | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Egetis Therapeutics | Stockholm, Sweden | Specialty Pharmaceuticals |
| MabSpace Biosciences | , | Renamed Transcenta |
| Averitas Pharma | , | Acquired by Grunenthal Nov 2018 |
| Wright Medical | , | Bought by Stryker, Nov 2020, $4.7B |
| , | Website down Dec 2025 - Mar 2026 | |
| AudioCure Pharma | Berlin, Germany | Inner Ear Treatments |
| Dimera | , | Website lists an exec who left in 2002 as being active |
| Verisante Technology | , | Acquired via Reverse Merger and seems to have left life sciences, Apr 2018 |
| Oryzon Genomics | Barcelona, Spain | Biomarker Identification, Drugs |
| Covalent Bioscience | , | Shut down, 2025? |
| AbboMax | San Jose, CA | Antibody, peptide, and assay product and service provider |
| Genome Protection | , | Website down Feb 2023 - Jul 2023; Unknown drug types Feb 2021 - Jul 2021 |
| Synthink Research Chemicals | Pune, India | Research Impurities |
| Hera Health Solutions | Memphis, TN | Bioerodible Drug Delivery Implants |
| , | Website taken over, Nov 2025 | |
| Breathe BioMedical | Cambridge, MA | Breath Diagnostics |
| Enovalife | Brussels, Belgium | Biometrics and medical writing services |
| Handl Therapeutics | , | Acquired by UCB, Nov 2020 |
| Domabio | Suzhou, China | ADCS, Inhibitors |
| FirstString Research | , | Renamed Xequal May 2022; Acquired by Relief Therapeutics, Jul 2016 |
| Scandipharm | , | Bought by Axcan Pharma, $100M |
| Attenua | , | Acquired by CODA Biotherapeutics, Feb 2020 |
| Micropore Technologies | Hyderabad, India | Membrane-Based Process Equipment |
| Apta Biosciences | , | Auctioning off assets, Aug 2020 |
| Cielo Therapeutics | , | Website gone, side gig for sole employee, annual report filed Feb 2017 |
| , | Website down Nov 2025 - Apr 2026 | |
| Biotechrabbit | Berlin, Germany | PCR, Antibodies, lab products |
| Qitan Tech | Chengdu, China | Nanopore Sequencing |
| Oxford Nanopore | Oxford, UK | Molecular Analysis |
| Binax | , | Acquired by Alere, Feb 2005, $9M |
| , | Aquired by Boston Scientific, May 2025, $540M | |
| Schivo | Waterford, UK | Medical Device Contract Manufacturing |
| Pronostics | , | Assets acquired by Phadia, Jan 2009 |
| CytoTronics | Boston, MA | Optics-free Imaging for Drug Discovery |
| Spyryx Biosciences | , | Shut down 2019 |
| Tioga Medical | , | Renamed Tioga Cardiovascular |
| Apollo Pharmaceuticals USA | , | Website down Jul 2023 - Dec 2023; Acquired by Provepharm Life Solutions, Dec 2020 |
| NuBioPharma | , | Website down Apr 2023 - Oct 2023 |
| Genomic Vision | , | Website Down May 2024 - Nov 2024 |
| Octagon Therapeutics | , | Winding Down Apr 2025 |
| CardiRen Biomedical | , | Gone Aug 2017 |
| Sirion Therapeutics | , | Sold drugs to Alcon, 2010 |
| ElsaLys Biotech | , | Website down Jan 2023 - Jul 2023 |
| Inhibrx | , | Acquired by Sanofi, May 2024, $1.7B |
| Xenotrans | , | Assets purchased by Revivicor, Jun 2005 |
| Ariana Pharma | Cambridge, MA | Clinical & Biomarker Data Analytics |
| Abeona Therapeutics | Cleveland, OH | Therapies for Sanfilippo (SF) Syndrome Type A and Type B. |
| IQVIA | Durham, NC | Clinical Research |
| Phortas | Aachen, Germany | Regulatory Affairs and Drug Development Consultancy |
| G2GBIO | Chungcheongbuk, Korea | Microspheres for Dermal Filler |
| Microba Life Sciences | Brisbane, Australia | Metagenomics Platform for Bacteriome Drug Discovery |
| OncoTx | , | Merged into General Oncology, Nov 2015 |
| Immucor | , | Acquired by Werfen, Mar 2023, $2B |
| MIFCOR | , | Founders both gone Feb 2021 |
| Acidophil | , | Gone late 2022 |
| Chiesi | Santana de Parnaíba, Brazil | Small Molecules, Biologics, Orphan Drugs |
| Ortho-McNeil-Janssen | , | Now Janssen Pharmaceuticals |
| Serum Life Science Europe | Hanover, Germany | Biologic, Small Molecule, Vaccine Consulting |
| Adenosine Therapeutics | , | Bought by Clinical Data, Aug 2008, $11M |
| Mojo Vision | , | Not a registered business in CA Apr 2020 - Aug 2022, no employees on LI Aug 2022 |
| OXON | Madrid, Spain | Real World Evidence |
| Thermedx | , | Website down Aug 2022 - Nov 2022 |
| Catalent | Madison, WI | Biologics Manufacturing & Cell Line Development |
| ABD Bioquest | , | Renamed AAT Bioquest |
| |
Valladolid, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Gengine | , | Renamed Editas Medicine, 2013 |
| Biowest Therapeutics | , | Website Gone |
| VIVUS | Campbell, CA | Small Molecules |
| Sepset Biosciences | Victoria, BC | POC Blood Diagnostic |
| PixCell Medical | Yokneam, Israel | POC Blood Diagnostics |
| Iterative Health | Cambridge, MA | Products & Services for Gastroenterology |
| Medtronic | Memphis, TN | Medical Devices |
| Eppendorf | Enfield, CT | Wide Range of Scientific Products |
| Wugen | St. Louis, MO | Off-the-shelf Cell Therapies for Cancer |
| genOway | Lyon, France | Rat and cell models |
| Precision Genome Engineering | , | Rebranded Pregenen in 2011 |
| Kures | , | Website down Sep 2024 - Feb 2025; Inside ATAI for now |
| Devon Medical Products | , | Website down Jun 2023 - Dec 2023 |
| Apcer Life Sciences | Jersey City, NJ | Consultants |
| Cypralis | , | website ©2015, No news 2018 - May 2025; Spun out of Selsia, 2013 |
| Theertha Biopharma | , | Website down Apr 2023 - Sep 2023 |
| Faze Medicines | , | Shutting down Nov 2022 |
| Accera | , | Renamed Cerecin, Oct 2018 |
| Vaporox | Lone Tree, CO | Wound Care Medical Device |
| 180 Life Sciences | , | Pivoted to crypto, Aug 2025 |
| Mevion Medical Systems | Tokyo, Japan | Radiation Therapy |
| Park Therapeutics | , | Acquired by Tris Pharma, Apr 2021 |
| Theragent | Arcadia, CA | Cell Therapy CDMO |
| Avidex | , | Bought by MediGene, Aug 2006, $62.4M |
| Adynxx | , | Website taken over Sep 2020 |
| Denovo Biomarkers | , | Changed name to Denovo Biopharm |
| General Automation Lab Technologies | , | Renamed Isolation Bio, Sep 2022 |
| Crystal Pharmatech | Cranbury, NJ | Contract research - materials science and engineering for drug development |
| Stago | Maastricht, Netherlands | Diagnostics |
| ImmunoACT | Navi Mumbai, India | CAR-T Manufacturing |
| EngMab | , | Bought by Celgene, Sep 2016, $625M + $2.4B milestones |
| , | Website down Jan 2026 - Apr 2026 | |
| Herantis Pharma | Espoo, Finland | Biologic for Parkinson's |
| TKL Research | Fair Lawn, NJ | Clinical Research |
| Adaptix | Oxford, UK | Medical imaging |
| PharmedArtis | , | Gone 2019 |
| Slainte Bioceuticals | , | Gone |
| Adragos Pharma | Kawagoe, Japan | Global CDMO for sterile injectables: PFS, vials, ampoules, IV bags, BFS. Clinical to commercial. |
| Taxolog | , | Website gone, Nov 2015 |
| Samsara Sciences | , | Shut Down Mar 2020 |
| AstraZeneca | Mississauga, ON | Small Molecules, Vaccines, Biologics |
| Acessa Health | , | Acquired by Hologic, Aug 2020, $80M + Milestones |
| Aquilon Pharmaceuticals | Liege, Belgium | Inhalable Drugs |
| Celleron Therapeutics | , | Merged with Argonaut Therapeutics, Jan 2023, to become IngeneOx Therapeutics |
| nanoMR | , | Bought by DNA electronics, Jan 2015, $24M |
| ACM Biolabs | Singapore, Singapore | Customized membrane protein products, services and expertise |
| Principia Biopharma | , | Acquired by Sanofi, Sep 2020 |
| JSS Medical Research | Faridabad, India | Clinical Research & Consulting |
| MindRank | Shanghai, China | AI Drug Discovery |
| Life Analytics Group | , | Gone |
| RenalSense | , | Website down Jul 2024 - Dec 2024 |
| Pelthos Therapeutics | Durham, NC | Specialty Pharmaceuticals |
| Rafarm | Athens, Greece | Ophthalmics CDMO |
| Actelion Pharmaceuticals | , | Acquired by J&J, Jun 2017, $30B |
| Rox Medical | , | Gone 2019 |
| MicroAire Surgical Instruments | Charlottesville, VA | Surgical Devices |
| Cephalogics | , | Assets acquired by Invisio Medical, Feb 2018 |
| Fennec Pharmaceuticals | Durham, NC | Small Molecules, Cyclic Peptides |
| ConquerX | , | Dissolved Jun 2021 |
| Immune Targeting Systems | , | Acquired by Vaxin, Feb 2015 |
| Bio-Tissue | Miami, FL | Amniotic Membranes |
| Integer | Salem, VA | Medical & Surgical Devices |
| Auven Therapeutics | , | No news 2020 - Nov 2024 |
| AOP Orphan Diseases | Vienna, Austria | Orphan disease treatments |
| Renaissance Pharma | , | Acquired by Essential Pharma, Apr 2024 |
| R-Tech Ueno | , | Acquired by Sucampo, Aug 2015, $276B |
| Brunswick Labs | , | Website down Oct 2020 - Mar 2021 |
| Armetheon | , | Merged with Espero Pharma, Mar 2017 |
| Eximias Pharmaceutical | , | Acquired by YM BioSciences, May 2006 |
| Advanced Circulatory | , | Bought by Zoll Medical, Mar 2015 |
| Cellomatics BioSciences | Nottingham , UK | Contract Lab Research - Oncology, Respiratory, Immunology |
| Coherence Neuro | San Francisco, CA | Cancer Therapy Wearable |
| Cytos Biotechnology | , | Merged with Kuros Biosurgery to become Kuros Biosciences, Dec 2015 |
| Adnavance Technologies | , | Dissolved, Apr 2010 |
| Boston Clinical Trials | Boston, MA | Clinical Research |
| Hillstar Bio | Boston, MA | Next-Gen Immunotherapies |
| Advent Bioservices | Cambridge, UK | GMP Manufacturing, Cold Storage, Process Development |
| EndoStim | , | Shut down Jan 2020 |
| Keosys | , | Acquired by Banook Group, Jun 2024 |
| Motif BioSciences | , | Shut down except as a shell, Jan 2020 |
| , | No news 2017 - Apr 2026 | |
| Ledger Run | Raleigh, NC | Clinical Trial Platform |
| Ammonett Pharma | , | Licensed a drug to Lumos Pharma, Sep 2018, no website no info Feb 2019 |
| ClearPoint Neuro | Carlsbad, CA | Minimally invasive surgical procedures in the brain and heart under direct, intra-procedural MRI guidance |
| Moat Biotechnology | , | Inhaled Covid Vaccine |
| Aeirtec | North Shields, UK | Biomarkers, Biostatistics, Gene Expression |
| Corcym | London, UK | Implants, Instruments |
| Translucence Biosystems | Irvine, CA | 3D Analysis of Biological Samples |
| Surface Logix | , | Bought by Nano Terra |
| Recludix Pharma | Cambridge, MA | Programs targeting STAT3 and STAT6 |
| , | ||
| Pharminox | , | Website gone, Aug 2017 |
| ChondroGene | , | Now GeneNews |
| Banyan Biomarkers | , | Website down Nov 2023 - Apr 2024; LI page gone Nov 2023 |
| NeuMed | , | Website four years since update, no employees on LI |
| Johnson and Johnson Innovative Medicine | Malvern, PA | Small Molecules, Biologics |
| Omeros | Seattle, WA | Small Molecules |
| AtCor Medical | , | Now part of CardieX |
| Venomyx Therapeutics | , | Website taken over Mar 2024; Not registered in CA Feb 2024 |
| Hawaii Chitopure | , | Merged with BioSTAR West and became Synedgen 2009 |
| MedQIA | , | Renamed Voiant Clinical, Sep 2023 |
| RefleXion Medical | Hayward, CA | Biology-guided Radiotherapy |
| Receptor Life Sciences | , | Website down Dec 2024 - May 2025; Using MannKind's inhalation tech |
| QuidelOrtho | Athens, OH | Molecular Diagnostics |
| Vela Diagnostics | Fairfield, NJ | Molecular Diagnostics |
| ZebiAI Therapeutics | , | Acquired by Relay Therapeutics, Apr 2021, $85M |
| |
Newark, DE | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Trials, and Clinical Development. |
| Velocity Medical Solutions | , | Acquired by Varian Medical, Apr 2014 |
| Elite Research Institute | , | Gone, May 2018 |
| Vodori | Chicago, IL | Commercial Content Software |
| XtalPi | Beijing, China | AI Drug Design |
| AccuTheranostics | , | Website down May 2020 - Aug 2020, taken over Sep 2020 |
| X4 Pharmaceuticals | Boston, MA | Oral small molecules |
| Arcinova | , | Acquired by Quotient Sciences, Feb 2021 |
| Lacer | Barcelona, Spain | Small Molecules |
| Ansa Biotechnologies | Emeryville, CA | Next Generation DNA Synthesis |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| AELIX Therapeutics | , | Website down Feb 2025 - Mar 2025; sold sole asset to Gilead, Nov 2024 |
| Somaxon Pharmaceuticals | , | Bought by Pernix Mar 2013, Renamed Pernix Sleep |
| Abazyme | , | Dissolved Jun 2017 |
| Sanochemia Pharmazeutika | Neufeld an der Leitha, Austria | Medicines |
| 48Hour Discovery | Edmonton, AB | Peptide-based radiopharmaceuticals for the treatment of cancer |
| Curida | Elverum, Norway | CDMO: Small Molecule and Biologics, including Monoclonal Antibodies |
| Biomedica Diagnostics | Windsor, NS | Diagnostics |
| Aspen Biosciences | San Diego, CA | Software solutions for drug discovery and diagnostics challenges |
| Toxikon | , | Acquired by Labcorp, Dec 2021 |
| CardiaLen | , | Assets acquired by Maxwell Biomedical, Dec 2022 |
| ViroCyt | , | Acquired by Sartorius, Jul 2016, $16M; Spun out of InDevR |
| Hologic | Newark, DE | Diagnostic, Imaging |
| EdgeOne Medical | Wheeling, IL | Combination Product Consulting |
| Vessel Biosciences | , | Shut down Mar 2023 |
| LimmaTech Biologics | Schlieren, Switzerland | Glycans |
| , | No news Nov 2021 - Jun 2026; fka RegeneraTEch | |
| ARTBIO | Oslo, Norway | Radioligand therapy |
| CardioCanary | , | Founders gone. Doubt it's active |
| Resolve M Therapeutics | Boston, MA | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| BioClinical Solutions | Chicago, IL | Clinical Trial Solutions |
| Agrisera | Vännäs, Sweden | Antibodies |
| Integer | El Paso, TX | Medical & Surgical Devices |
| Proimmune | Oxford, UK | Immunology research products |
| Bioskin | , | Acquired by eurofins, Aug 2021 |
| Medinol | Tel Aviv, Israel | Stent design and technology |
| Imbed Biosciences | Middleton, WI | Wound Dressings |
| Proxygen | Vienna, Austria | Cancer Therapies |
| , | Website down, CEO gone Apr 2026 | |
| OneVax | , | Website down Jul 2020 - Dec 2020 |
| DSP Clinical Trials | Montclair, NJ | Clinical Research |
| Meru Biotechnologies | , | Website taken over, LI page gone Nov 2023; Website down Jun 2023 - Oct 2023 |
| Biosight | , | Merged with Ayala Pharmaceuticals, Oct 2023 |
| GenoMatrix | , | Renamed Intrexon, Aug 2005 |
| RedoxTherapies | , | Acquired by Juno, Jul 2016, $10M + milestones |
| Narus Biotechnologies | , | Acquired by Cofactor Genomics, Feb 2016 |
| PTM BioLabs | , | Renamed PTM BIO |
| Proof Diagnostics | , | Acquired by Ginkgo Bioworks, Feb 2024; fka Pine Trees Health |
| Eurofins MWG Operon | , | Now eurofins Genomics |
| Prasco Laboratories | Mason, OH | Authorized Generics |
| Origenix | , | Acquired by Micrologix Biotech, Sep 2002, $320M |
| Apeiron Biologics | , | Royalty Company, moved all assets into inVIos, Jan 2022 |
| Rigicon | Ronkonkoma, NY | Penile Prosthesis |
| Rexam Healthcare Devices | , | Changed name to Nemera, Jul 2014 |
| Scythian Biosciences | , | Renamed SOL Global, Oct 2018 |
| Inquis Medical | Menlo Park, CA | Venous thromboembolism treatment |
| D5Pharma | , | Website copyright 2014, no location, no employees |
| Revvity | Waltham, MA | Diagnostics, Services |
| OtiTopic | , | Website down Sep 2021 - Jan 2022 |
| Atlab Pharma | , | Bought by Telix Pharmaceuticals, Jan 2017 |
| Vericel | Cambridge, MA | Cellular Therapy |
| Kardigan | Princeton, NJ | Seems to be Small Molecules |
| Experimentica | Kuopio, Finland | Global contract research organization specialized in preclinical ocular models and R&D services for ophthalmic indications |
| CRIO | Boston, MA | eClinical Software |
| GenturaDx | , | Bought by Luminex 2012 |
| Aphios | Woburn, MA | Small Molecules, 'Green' Biotechnology |
| Stellate Biotherapeutics | , | Renamed Full Circles Therapeutics |
| arGentis Pharmaceuticals | , | Website down Sep 2023 - Mar 2024; Still has employees, never registered in TN as of Feb 2021, Clin1 results were expected in 2015, but no news as of Feb 2021 |
| Pulnovo Medical | Shanghai, China | Cardio Devices |
| CordenPharma | Bergamo, Italy | Contract Small Molecules |
| IOmet Pharma | , | Acquired by Merck, Jan 2016, $400M |
| Mariel Therapeutics | , | Merged with Ember Therapeutics, Mar 2015 |
| ARC Medical | , | Acquired by Typenex Medical |
| Nature Technology | , | Acquired by Aldevron, Jan 2022 |
| CONMED | Westborough, MA | Surgical, Medical Devices |
| ProtaGene | Burlington, MA | Advanced, integrated, and complete analytical solutions and expert consultation. |
| Oculos Clinical Research | , | Acquired by iuvo BioScience, Jul 2018 |
| Althera Pharmaceuticals | Swords, Ireland | Generics |
| , | Acquired by Pfizer, Nov 2025, $10B | |
| TriRx Pharmaceutical Services | Norwalk, CT | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| ALTx Therapeutics | , | Small Molecule Therapies |
| Zina Biopharmaceuticals | Germantown, | Specialized Clinical Trial Consulting |
| NasVax | , | Renamed TheraPix Biosciences Nov 2013 |
| Medunik Canada | Blainville, QC | Bringing orphan drugs to Canada |
| Peptisyntha | , | Solvay Subsidiary until Acquired by CordenPharma Aug 2013 |
| , | Website down Dec 2025 - Apr 2026; Ecole Polytechnique Fédérale de Lausanne spinoff; Celgene $55M option to buy Jan 2017 | |
| Bend Bioscience | Clearwater, FL | Contract Development & Manufacturing |
| Evaxion | Hørsholm, Denmark | AI-driven Immunotherapies |
| Taris Biomedical | , | Acquired by J&J, Dec 2019 |
| Fastbase Solutions | , | Renamed HAWK Biosystems |
| PentixaPharm | Würzburg, Germany | Radiopharmaceuticals |
| Distributed Bio | , | Acquired by Charles River, Jan 2021, $83M + $21M milestones |
| AcelaBio | San Diego, CA | Histopathology and Precision Medicine Services for Global Clinical Trials |
| Limelight Bio | , | Website down Sep 2020 - Feb 2023 |
| Shionogi | Florham Park, NJ | Small Molecules |
| OnQuality Pharmaceuticals | , | Website down Jul 2025 - Aug 2025 |
| Venenum Biodesign | Hamilton, NJ | Molecular & discovery biology, biochemistry, medicinal and analytical chemistry, assay development, protein engineering & production, ultra-high throughput screening |
| Ascentawits Pharmaceuticals | Beijing, China | Small Molecule |
| IsoPlexis | , | Acquired by Berkeley Lights, Mar 2023, $57.8M |
| Shionogi | Osaka, Japan | Small Molecules, Injectors |
| Galil Medical | , | Acquired by BTG plc, May 2016 |
| EnGenome | Pavia, Italy | Genomic Diagnostic Platform |
| 35Pharma | Montreal, QC | Ligand Traps for Diseases of High Unmet Medical Need |
| Tiger Wound Care | Conshohocken, PA | Wound Care, Pain Management |
| Vista.ai | Palo Alto, CA | MRI Software |
| PegaOne | , | Centessa Company |
| Anchor Therapeutics | , | Presumed gone; fka Ascent Therapeutics |
| Wren Laboratories | Branford, CT | mRNA Liquid Biopsy |
| Pharmaceutical Solutions | , | Acquired by HiRo |
| SGI-DNA | , | Renamed CODEX, Apr 2020 |
| , | Website down Aug 2025 - Jan 2026 | |
| AbbVie | North Chicago, IL | Small Molecules, Biologics, Contract Manufacturing |
| Mitralign | , | Some assets bought by Edwards Lifesciences, Mar 2019 |
| Cannabis Science | , | Seems inactive Nov 2023 |
| Sapient Bioanalytics | San Diego, CA | Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation |
| Sonoma Orthopedics | , | Acquired by Arthrex, Jul 2017 |
| Sanyou Biopharmaceuticals | Shanghai, China | Reagents, Antibodies, Lab Supplies |
| Synpac | , | No website, trials started in 1999. Genzyme may have taken control of product |
| Roxane Labs | , | Acquired from Boehringer-Ingleheim by Hikma, Feb 2016, merged into West-Ward Laboratories |
| Recbio Technology | Taizhou, China | mRNA Covid Vaccine |
| Zentalis Pharmaceuticals | San Diego, CA | Small Molecules |
| Almac | Durham, NC | Pharmaceutical Services |
| Novartis | East Hanover, NJ | Small Molecules, Vaccines, Biologics |
| Austrianni | Vienna, Austria | Antibodies and small molecules for treating tuberculosis |
| Ipsen | Sumter, SC | Biologics |
| Hemanext | Avon, MA | Transfusion Technologies |
| Wilmington Pharmaceuticals | , | Website down Jan 2021 - May 2021 |
| Benten Biotech | Montevideo , Uruguay | Antibodies, nanobodies and vaccine technologies |
| Lumenblation Medical | , | Renamed Supira Medical, Mar 2016 |
| AWAK Technologies | , | Renamed Vivance, Oct 2024 |
| , | Acquired by Immedica, Feb 2025 | |
| LabTwin | , | Merged with Labforward |
| OccuRx | , | Merged into Certa Therapeutics |
| Ascentage Pharma | Shanghai, China | Small molecule cancer therapeutics |
| Deimos Biosciences | , | |
| Recordati | Milan, Italy | Small Molecule Manufacturing |
| Telomere Diagnostics | , | Business filings late mid-2023, seems to have pivoted to consumer Covid testing?; Acquired by Orig3n, Late 2020 |
| Delpharm | Leiden, Netherlands | Contract Manufacturing |
| Imvax | Philadelphia, PA | Personalized Vaccines, Immunotherapy |
| Bio Genuine Biotech | Shanghai, China | Small Molecules |
| Verathon | Amsterdam, Netherlands | Bronchoscope, Bladder scan, airway visualization system |
| Reveris Therapeutics | , | People all left or have other, real jobs |
| Baxter | Alliston, ON | Medication Delivery |
| Gedeon Richter | Budapest, Hungary | Small Molecules, Generics |
| EAG Laboratories | Santa Clara, CA | Analytical & Synthesis Services |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| Kuros Biosurgery | , | Merged with Cytos Biotechnology to become Kuros Biosciences, Dec 2015 |
| Ajinomoto Bio-Pharma Services | Wetteren, Belgium | Contract Manufacturing |
| Charles River Laboratories | Margate, UK | Research Animal Models and Preclinical Research |
| Two Pore Guys | , | Renamed Ontera, Dec 2018 |
| Proteologics | , | Apparently Gone |
| NOTA Labs | Ann Arbor, MI | Nitric Oxide |
| Genesis RandD | , | Ceased operations in 2010. Out of money. |
| Worldwide Clinical Trials | St. Petersburg, Russia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Hexal | , | Acquired by Sandoz, Jun 2005 |
| Amakem | , | Website gone Dec 2015 |
| , | No news 2016 - Sep 2025 | |
| GenSensor | Nantes, France | Process Analytical Technology |
| Evas Therapeutics | , | SBIR grant. No info Jun 2015. Google says closed Aug 2019 |
| Gerard Biotech | , | Lab supplies, seems defunct |
| BliNK Biomedical | , | Only employee is noted as being former CEO on his new company's website, Mar 2025 |
| Archimedes Vascular | Birmingham, | Hypertension Devices |
| |
Utrecht, Netherlands | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Cogitars | Heidelberg, Germany | Life Sciences Consulting |
| SouthernBiotech | Birmingham, AL | Research Antibodies |
| Aplex Bio | Solna, Sweden | Next-gen PCR-Hyperplexed PCR |
| Frugi Biotechnology | , | Acquired by BigHat Biosciences, Mar 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Sapho Bio | San Carlos, CA | Rapid microbiology release platform for precision medicine |
| PharmaLex | Hørsholm, Denmark | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| , | Stopped work Aug 2025, IP company | |
| 858 Therapeutics | San Diego, CA | Precision Oncology |
| Blend Therapeutics | , | Renamed Tarveda Therapeutics, Jan 2016 |
| Freenome | Brisbane, CA | Cancer Diagnostics |
| ACT Oncology | , | Acquired by Precision for Medicine, Mar 2016, renamed Precision Oncology |
| Afraxis | , | Business filings years late, no employees on LI Jun 2022 |
| Ichorion Therapeutics | , | Acquired by Cerecor, Sep 2018, $26.6M |
| Diatos | , | No website, founded 1999 |
| Permeon Biologics | , | Website taken over, Oct 2017 |
| Becton Dickinson | San Diego, CA | Various medical devices and health products |
| SI-BONE | Santa Clara, CA | Sacroiliac joint fusion device |
| ECHOBIO | , | Website down Jul 2021 - Nov 2021 |
| Redbiotec | , | No news 2020 - May 2025; Food ingredients may be main thing |
| Transmotion Medical | , | Assets acquired by Winco, Jun 2015 |
| EndoGlow | Rochester, NY | Fluorescent Surgical Manipulator |
| Grit Biotechnology | Shanghai, China | Tumor-infiltrating lymphocyte therapies |
| Adheron Therapeutics | , | Bought by Roche, Oct 2015, $105M + $475 Milestones |
| Avvinity Therapeutics | , | Dissolved Nov 2024 |
| Deuracor Therapeutics | , | No website Jul 2019 - May 2023; 2019 BIO attendee |
| Asher Biotherapeutics | South SF, CA | IL-2 Therapies |
| Jupiter Orphan Therapeutics | , | Renamed Jupiter Neurosciences, 2021 |
| CiToxLAB | , | Acquired by Charles River, Apr 2019, €448M |
| Firalis | Huningue, France | Biomarker Discovery, Development, Regulatory Qualification |
| Tubulis Technologies | Planegg-Martinsried, Germany | Antibody drug conjugate discovery and development platform |
| AnaptysBio | San Diego, CA | Antibody Therapeutics |
| Lucigen | , | Acquired by LGC, Feb 2018 |
| Loxo Oncology | , | Bought by Eli Lilly, Feb 2019, $8B |
| AxonDx | , | CEO has numerous other more important jobs, Feb 2025 |
| EDAP Technomed | Austin, TX | Robotic high-intensity focused ultrasound (HIFU) systems for prostate tissue ablation |
| NCS Pharmaceuticals | , | Website is 12 years old as of Dec 2019 |
| Alissa Pharma | , | Doesn't seem serious, Feb 2024 |
| Tioga Pharmaceuticals | , | One employee left Oct 2022 after having received $18M in 2010 |
| Convalife Pharmaceuticals | Shanghai, China | Oncology, viruses and aging treatments; bispecific antibodies, small molecules |
| FluoFarma | , | Acquired by Porsolt, Dec 2015 |
| Viatem | , | Website down Dec 2020 - Sep 2021 |
| , | Website down Aug 2025 - Jan 2026 | |
| Gate Bioscience | Brisbane, CA | Molecular Gates |
| Neura Therapeutik | , | No website Dec 2020; Single-person company?, Dec 2019 |
| Microviable Therapeutics | Gijon, Spain | Intestinal Microbiota Isolation Kit |
| Systems Medicine | , | Acquired by CTI Jul 2007 |
| Cougar Biotechnology | , | Bought by J&J |
| B. Braun | Melsungen, Germany | Infusion therapy and pain management |
| Prima Biomed | , | Changed name to Immutep, Nov 2017 |
| Genesee Biomedical | Denver, CO | Cardiac Surgical Devices |
| , | Website down Aug 2025 - Jan 2026 | |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Acclaim Biotechnology | , | Received SBIR in 2004, no website, no employees |
| LuinaBio | , | Renamed AcuraBio, Aug 2022 |
| Crescenta Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Applied Clinical Intelligence | , | Renamed ACI Clinical |
| ValiRx | Nottingham, UK | Cancer therapies & diagnostics |
| Effigene Pharmaceuticals | , | Either sold tech or closed down |
| BiosanaPharma | Leiden, Netherlands | Biosimilars, Oral Delivery of Biologics |
| Pharma Medica | Mississauga, ON | Clinical Services |
| Piedmont Pharmaceuticals | , | Renamed Piedmont Animal Health |
| Echelon Biosciences | Salt Lake City, UT | Assays & Reagents |
| Advanced Chemistry Development | Toronto, ON | R&D Software |
| Codex Biosolutions | , | Renamed Dexorgen, Jan 2024 |
| ABM Respiratory Care | Bangalore, India | Airway Clearance Systems |
| Realist Pharma | , | Graduated from Jlabs, Jan 2016, no info since then |
| PxRadia | , | Website gone Jan 2019, Not updated since 2014 |
| Sierra Oncology | , | Acquired by GSK, Jul 2022, $1.9B |
| Berlin Cures | , | Website down Feb 2025 - Jul 2025 |
| Micar Innovation | Sofia, Bulgaria | Drug discovery factory |
| Meridian Medical Technologies | , | Merged into Kindeva, Dec 2022; Acquired by Altaris, Dec 2021 |
| Trophea Development | , | Liquidated Dec 2019 |
| , | Website down Oct 2025 - Feb 2026; Legal troubles 2024 | |
| Takeda | Cambridge, MA | Small Molecule, Enzymes |
| Cradle Genomics | , | Website down Feb 2023 - Jul 2023 |
| Sphinx Pharmaceuticals | , | Acquired by Eli Lilly Mar 1994 |
| Orthofix International | Lewisville, TX | Medical Devices |
| EverInsight Therapeutics | , | Merged with AffaMed Therapeutics, Oct 2020, seems to have taken their name |
| Aquaro Biosystems | , | Renamed Aquaro Histology |
| Pioneer GMP Consulting | Newton, MA | Business minded GMP-compliant solutions that enable a competitive advantage |
| AiCuris | Wuppertal, Germany | Anti-Infectives |
| Precirix | Brussels , Belgium | Radiopharmaceuticals based on linking single domain antibody fragments with radioisotopes to treat cancer |
| ProtonIntel | Vancouver, BC | Real-time, continuous potassium monitoring for CKD |
| DNA Software | Plymouth, MI | PCR Primer Design Software, Multiplex Assay Design, Oligonucleotide Modeling for Molecular Diagnostics |
| , | Renamed Cellular Intelligence, Jan 2026 | |
| Lipid Therapeutics | , | Does not seem active Oct 2019 |
| H.E.L. Group | Thane, India | Parallel and high pressure biotechnology lab equipment |
| XO1 | , | Bought by J&J, Mar 2015 |
| Amber Bio | San Francisco, CA | Gene Editing Platform |
| Northway BiotechPharma | , | Renamed Northway Biotech |
| Tegra Medical | Franklin, MA | Contract Medical Device Manufacturer |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Septodont | Lancaster , PA | Dental pharmaceuticals (pain managements, endodontics & restorative, regeneration & surgery) |
| CombinatoRx | , | Now Zalicus |
| Doctor Pack | Bangalore, India | Packaging |
| SanBio Co Ltd | Oakland, CA | Regenerative Cell Medicine |
| Zymogenetics | , | Bought by BMS, Sep 2010, $885M |
| Pinnacle Biologics | , | Bought by Concordia Healthcare Dec 2013 |
| Ypsomed | Burgdorf, Switzerland | Self-injection systems |
| Chemveda Life Sciences | San Diego, CA | Drug Discovery & development Services |
| OncoStem Diagnostics | Bangalore, India | Tumor Diagnostics |
| Calixar | Lyon, France | Membrane Proteins |
| NewStem | , | Website down Feb 2025 - Jul 2025 |
| Oragenics | Sarasota, FL | Oral Care Probiotics |
| , | Renamed Genetix Biotherapeutics, Sep 2025 | |
| SMG Pharmaceuticals | , | No updates 2016-2023; Only product is a topical salicylic acid |
| Selexys | , | Bought by Novartis, Nov 2016, $665M |
| Genemo | , | Seems inactive, Jul 2024 |
| Argenta Discovery | , | Bought by Charles River Labs, Mar 2014 |
| Ocata Therapeutics | , | Acquired by Astellas, Jan 2016, $379M; fka Advanced Cell Technology |
| Baxter | Marion, NC | Medication Delivery |
| Gilero | Carlsbad, CA | Medical device design & development, drug delivery systems design & development |
| Structured Immunity | , | Website down Dec 2019 - Mar 2020 |
| Function Oncology | , | Website down Dec 2024 - May 2025 |
| Enzymatics | , | Bought by Qiagen, Jan 2015, Colorado facility spun off as ArcherDx |
| Pulsar Bio | , | Website down Nov 2024 - Apr 2025 |
| Sylvatica Biotech | Charleston, SC | Organ Cooling Technology |
| Accellacare | Downers Grove, IL | Clinical Research |
| Unity Biotechnology | , | Laid everyone off, May 2025, shut down |
| Therix Medical | , | Seems gone |
| IGNITE Immunotherapy | , | Website down Dec 2019 - Aug 2020 |
| Instratek | , | Assets acquired by Stryker, Sep 2016 |
| Artegraft | , | Acquired by Lemaitre Vascular, Jun 2020, $72.5M |
| ILIAS Biologics | Daejeon, Korea | Exosome Therapeutics |
| Diopsys | , | Acquired by LumiThera, Mar 2022 |
| Mello Biotechnlogy | , | Website down May-Nov 2018 |
| Luoxis | , | Merged with Vyrix Pharmaceuticals to become Aytu Bioscience, Apr 2015 |
| BG medicine | , | Gone 2019 |
| Galenica Senese | Monteroni D'Arbia, Italy | Contract Manufacturer |
| OWP Pharmaceuticals | Lisle, IL | Novel oral liquid formulations for neuroscience disorders |
| GATC Biotech | , | Acquired by eurofins, Jun 2017 |
| Varigen Biosciences | , | Renamed Terra Bioworks, Oct 2022 |
| MIRA1A Therapeutics | , | Renamed MIRA Pharmaceuticals, Jan 2023 |
| NovoLipid | , | Website Gone |
| Organogenesis | Canton, MA | Biologics |
| Euro Diagnostica | , | Renamed Svar Life Science, 2018 |
| Cellecta | Mountain View, CA | CRISPR and RNAi Genetic Screens, Libraries and Construct; Sequencing; RNA Expression Profiling; Barcode Libraries |
| Allucent | Tel Aviv, Israel | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| Almedica | , | Acquired by Aptuit, Sep 2005 |
| Halo Labs | , | Acquired by Waters, May 2025 |
| Transcriptogen | , | No website Jan 2020 - Jul 2024 |
| HealthTell | , | Seems gone, reincarnated as Calviri |
| Inventprise | Redmond, WA | Vaccines |
| Leyden Labs | Leiden, Netherlands | Antibodies for Viruses |
| T-Rx Pharmaceuticals | , | Renamed Adanate, Jul 2018 |
| BIA Separations | Ajdovščina, Slovenia | Separation Technology |
| PCI Pharma Services | Bedford, NH | Contract Manufacturing, Services |
| Pointcross Life Sciences | Foster City, CA | Big data analytics, management, and visualization |
| Alcon | Zug, Switzerland | Eye-Care Products |
| Expanding Innovations | Mountain View, CA | Non-screw based expandable cage technology |
| Veeva Systems | Pleasanton, CA | Life Science Software |
| Caelum Biosciences | , | Acquired by AstraZeneca, Sep 2021, $150M + $350M milestones |
| Captozyme | , | Acquired by Arrant Bio, Nov 2019 |
| Azalea Therapeutics | Berkeley, CA | Engineering Cells Directly Inside Each Patient |
| Mitsubishi Tanabe Pharma | Osaka, Japan | Small Molecules |
| Stately Bio | San Francisco, CA | ML Cell Imaging |
| Solentim | , | Acquired by Advanced Instruments, Aug 2021 |
| Peptides International | , | Merged with New England Peptide after PE buyout, Dec 2019 |
| BRIJ Medical | Marietta, GA | Scar Prevention Device |
| Scilligence | Auburn, MA | Web-based cheminformatics and bioinformatics solutions |
| UBC | King of Prussia, PA | Biopharmaceutical Consulting & Services |
| THERAtRAME | Liège, Belgium | Small molecules targeting the tRNA epitranscriptomics |
| Cytura Therapeutics | , | Website down Sep 2023 - Mar 2024 |
| Maze Therapeutics | South SF, CA | Small Molecules, Gene Therapy, Antisense Oligonucleotides, Biologics |
| Complix | Zwijnaarde, Belgium | Alphabodies |
| VacV Biotherapeutics | London , UK | Oncolytic Viruses |
| Fosun Pharma | Beijing, China | Small molecules, diagnostics, traditional |
| Azad Pharma | Schaffhausen, Switzerland | APIs, generics |
| APSciences | , | Website gone Aug 2022 |
| Verathon | Burnaby, BC | Bronchoscope, Bladder scan, airway visualization system |
| PharmaMar | Madrid, Spain | Marine-derived Compounds |
| Quotient Radiochemicals | , | Renamed Quotient Bioresearch |
| IM Therapeutics | , | Gone by 2023; aka Immunomolecular Therapeutics |
| NuPotential | , | No longer active business per LA business registry, Feb 2019 |
| PolyCore Therapeutics | , | Website down Dec 2023 - May 2024; Closely associated with LignaMed |
| GrapheneDx | Boston, MA | At-home Diagnostics |
| Verus Pharmaceuticals | , | Dissolved |
| Verasonics | Kirkland, WA | Research Ultrasound |
| , | Acquired by Sensei Biotherapeutics, Feb 2026 | |
| Angstrom Medica | , | Acquired by Pioneer Surgical, Oct 2007 |
| AUG Therapeutics | , | Not registered in MA 2021 - 2025 |
| Cox Biosciences | , | Website down Jan 2021 - Apr 2021 |
| , | Acquired by Altaris, Jan 2025; fka Hitachi Chemical Advanced Therapeutics Solutions; fka PTC Cell Therapy | |
| Aspen Pharmacare | Rio De Janeiro, Brazil | Small Molecules |
| Transimmune | Düsseldorf, Germany | Immunotherapy |
| Stem Cell Therapeutics | , | Changed name to Trillium Therapeutics, Jun 2014 |
| Inspyr Therapeutics | , | Shell company, Website gone Apr 2018; fka GenSpera, formerly in San Antonio, TX |
| ProBio | Nanjing, China | Genomics, Proteomics, Biologics |
| Integra LifeSciences | Shanghai, China | Medical Devices |
| NTZ Lab | , | No news 2015 - Nov 2024 |
| Therapeutic Proteins Inc | , | Now refer to themselves as TPI |
| OnCusp Therapeutics | New York, NY | Small Molecules, ADCs, Bispecifics |
| JSW Life Sciences | , | Acquired by QPS, Jan 2012 |
| Seven Bridges Genomics | , | Merged with UgenTec & PieranDx to become Velsera, Jan 2023 |
| Optera Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Autobio Diagnostics | Zhengzhou, China | Immunoassay Equipment |
| Centus Biotherapeutics | , | Website down Feb 2023 - Jul 2023; May be virtual or else jointly hosted at its owners facilities; JV between AstraZeneca & Fujiflim Kyowa Kirin Biologics |
| Nivalis Therapeutics | , | Merged into Alpine Immune Sciences, Apr 2017; fka N30 Pharmaceuticals |
| OrthogenRx | , | Acquired by Avanos Medical, Dec 2021, $160M |
| , | Acquired by Instem, Jul 2025 | |
| Laboratoires Genevrier | , | Acquired by IBSA, Aug 2021 |
| OnKure Therapeutics | Boulder, CO | Deacetylase Inhibitors for Cancer |
| NextImmune | , | Renamed NXI Therapeutics |
| Rosetta Inpharmatics | , | Bought by Merck 2001 |
| Epix Pharmaceuticals | , | Shut Down 2009; fka Predix Pharmaceuticals |
| SwiftScale Biologics | , | Acquired by Resilience, Dec 2021 |
| Theranos | , | Dissolving, Sep 2018 |
| Nova Biomedical | Waltham, MA | Sample Analyzers |
| Mindset Pharma | , | Acquired by Otsuka Pharmaceuticals, Oct 2023, $59M |
| PTC Therapeutics | Warren, NJ | Small Molecules, Gene Therapy |
| Peptinnovate | , | Renamed Immune Regulation, Nov 2019 |
| PCI Pharma Services | León, Spain | Contract Manufacturing, Services |
| Emisphere | , | Acquired by Novo Nordisk, Dec 2020, $1.8B |
| , | Website down Jul 2025 - Dec 2025 | |
| Tenpoint Therapeutics | London, UK | Vision-restoring Therapies |
| PML Microbiologicals | , | Bought by Bimerieux Dec 2008 |
| Cipla | Verna, India | Generics, APIs, Formulation |
| Daiichi Sankyo | Shinagawa, Japan | Small Molecules |
| Theregen | , | Personnel on website is outdated. No one LinkedIN works there |
| Kinnate Biopharma | , | Acquired by Xoma, Apr 2024 |
| Iktos | Paris, France | AI for New Drug Design |
| Nuvalent | Cambridge, MA | Structure-based Drug Design for Kinase Targeting |
| Biosynth | Jinan, China | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Ascidian Therapeutics | Boston, MA | Mutated exon replacement |
| Luminostics | , | Renamed Clip Health, Sep 2021 |
| Ornim Medical | , | Downward Spiral, most employees gone Dec 2018, website gone Jan 2019 |
| Antares Therapeutics | Boston, MA | Small Molecule Technologies |
| Sanovel | Istanbul, Turkey | Generics |
| , | Website taken over Feb 2026 | |
| neuro42 | San Francisco, CA | MRI, Robotic/AI platform |
| Amaryllis Nucleics | , | Acquired by Active Motif, Jan 2022 |
| AIDA Pharmaceuticals | , | Shell company Aug 2019 |
| Baymatob Operations | Leichhardt, Australia | Non-invasive device to monitor pregnancy and labor progression |
| Cadence Pharmaceuticals | , | Acquired by Mallinckrodt, Mar 2014, $1.4B |
| GeneDx | Gaithersburg, MD | Genetic Data |
| Cardiosolutions | , | Website down Nov 2020 - Feb 2021 |
| KoruBio | , | Website down Jun 2020 - Aug 2020 |
| Acceptys | , | Assets acquired by Patrys, Oct 2008 |
| Acris Antibodies | , | Acquired by OriGene Technologies, Sep 2015, became OriGene Europe |
| Dual Therapeutics | , | Presumed to have fizzled. Had partnership with BMS. Biomotiv affiliated |
| Novocol | Cambridge, ON | Sterile Manufacturing |
| Ambion | , | Bought by Applied Biosystems 2006 |
| Meribel Pharma Group | Dreux, France | Contract Manufacturing |
| QuantumBio | State College, PA | Protein characterization software |
| , | Website down Jan 2026 - May 2026 | |
| Iverson Genetics | , | No updates since 2016; moved from Seattle |
| T&T Scientific | , | Website gone May 2023 |
| Preora Healthcare | Evanston, IL | Early Cancer Detection |
| Celldom | San Diego, CA | Single-Cell Biology Platform |
| Amira Pharmaceuticals | , | Acquired by BMS, Jul 2011, $325M |
| OX2 Therapeutics | , | No news 2020- Oct 2024 |
| Siga | Corvallis, OR | Small Molecules |
| Inmunotek | Madrid, Spain | Extracts for allergy and immunology |
| Resilience | Hamilton, OH | Biomanufacturing |
| Beta Cat Pharmaceuticals | , | Renamed Iterion Therapeutics, Nov 2018 |
| Charles River Laboratories | Germantown, MD | Research Animal Models and Preclinical Research |
| ENYO Pharma | Lyon, France | Develops small molecules drug candidates in infectious & metabolic diseases and oncology |
| Atlanta Biologicals | , | Acquired by Bio-Techne, 2018 |
| AEON Biopharma | Irvine, CA | Therapeutic Botulinum Toxins |
| Aqueduct Neurosciences | , | Renamed Aqueduct Critical Care |
| AUM Cardiovascular | , | Website down Jul 2021 - Nov 2021 |
| Armune Bioscience | , | Acquired by Exact Sciences, Dec 2017 |
| Accuray | Chengdu, China | Directed Radiation Therapy |
| Teleflex Medical | Athens, Greece | Surgical and Medical Devices |
| Beacle | , | Founder gone, no info |
| Actym Therapeutics | Berkeley, CA | Microbial-based immunotherapy platform |
| Umoja Biopharma | Seattle, WA | Cellular immunotherapy platform |
| Grossmont Center for Clinical Research | , | Gone Jul 2022 |
| Innovus Pharmaceuticals | , | Acquired by Aytu Bioscience, Feb 2020 |
| SURGILOGIX | San Antonio, TX | Human tissue allografts |
| Telephus Biosciences | , | Website gone May 2021; fka Telephus Medical |
| One Drop Diagnostics | Neuchâtel, Switzerland | Diagnostic Machines |
| CURNA | , | Acquired by Opko Health, Feb 2011 |
| Valneva | Lyon, France | Antibody Discovery |
| INEX Pharmaceuticals | , | Gone May 2007? |
| , | Renamed Elumn8 Medical, Feb 2026 | |
| Develco Pharma | Schopfheim, Germany | Generics |
| Tango Therapeutics | Boston, MA | Cancer Therapeutics, Immuno-Oncology |
| , | Acquired by Donaldson Life Sciences, Jun 2022 | |
| SOCIUM | Tokyo, Japan | Contract Research |
| Nova Pharmaceutical | , | Merged with Scios, May 1992 |
| OMT Therapeutics | , | Renamed TeneoBio, Dec 2015 |
| Edesa Biotech | Markham, ON | Topicals & Suppositories |
| Altus Pharmaceuticals | , | Wound Down 2009; Assets acquired by Althea, May 2010 |
| , | Website down Aug 2025 - Jan 2026 | |
| Apriori Bio | Cambridge, MA | AI platform for viral variant identification |
| OccamzRazor | New York, NY | Modality agnostic treatments for complex diseases of brain aging |
| Stablix Therapeutics | New York, NY | Small Molecules |
| Nuvaira | Minneapolis, MN | Medical Devices for Breathing |
| Nanosonics | Indianapolis, IN | Ultrasound |
| Admescope | Oulu, Finland | ADME-tox services |
| Medvax Technologies | , | Website Gone, Mar 2017 |
| AndroScience | , | Ancient website, no news 2014-2023 |
| Pandion Therapeutics | , | Acquired by Merck, Feb 2021, $1.85B |
| CellProthera | Mulhouse, France | Stem cell transplant for cardiac conditions |
| , | Website down Dec 2025 - Apr 2026 | |
| Cardior Pharmaceuticals | Hanover, Germany | Non-coding RNA based therapeutics |
| Optiscan Biomedical | , | Website down Jul 2021, marked as closed on Google, Employees gone |
| Epigeneron | , | Website down Sep 2023 - Mar 2024, LI page gone Dec 2023 |
| Bioventus | Cordova, TN | Orthobiologics |
| Teitur Trophics | Aarhus, Denmark | SorCS-derived peptides |
| Asana BioSciences | , | Website down Jul 2024, hijacked Aug 2024 |
| Igenomix | Mexico City, Mexico | Contract genetic testing for reproductive health; covid-19 pcr |
| Transgene | Boston, MA | Viral Vector Therapeutics, Gene Therapy |
| MEDiSTRAVA | London, UK | Strategy & Clinical Consulting |
| I-tek Medical | St. Paul, MN | Contract Device Manufacturing |
| Medherant | Coventry, UK | Transdermal drug delivery patches for pain and CNS diseases |
| Tridien Medical | , | Moved out of country, Feb 2018, no website, presumed gone |
| Pfizer | Kirkland, QC | Small Molecules, Biologics, Vaccines |
| Katana Pharmaceuticals | , | Founder and Website gone, Nov 2020 |
| Valora Therapeutics | La Jolla, CA | Immunotherapy Drug Discovery Platform, AbLecs |
| Medix Biochemica | Espoo, Finland | Monoclonal antibodies, antibody services, recombinant antigens, diagnostics |
| Tune Therapeutics | Durham, NC | Epigenetic modification to modulate gene expression |
| Moray Medical | , | aka Project Moray; not registered in CA Aug 2021 - Feb 2024 |
| Celsus Therapeutics | , | Merged with Volution Immuno-pharmaceuticals to become Akari Therapeutics, Aug 2015 |
| Yumanity Therapeutics | , | Reverse merged with Kineta, Dec 2022 |
| Bellus Health | , | Acquired by GSK, Jun 2023, $2B |
| Sunshine Heart | , | Changed name to CHF solutions, May 2017 |
| Newbury Pharmaceuticals | Lund, Sweden | Specialty Pharmaceuticals |
| Deinove | , | Bankrupt Mar 2023 |
| ACROBiosystems | Basel, Switzerland | Proteins, antibodies, kits, GMP-grade reagents, and custom services |
| Ascend Genomics | , | Shut down |
| Benchling | San Francisco, CA | Biotech Software |
| Actinogen Medical | West Perth, Australia | Small Molecule for Alzheimer's |
| Enovalife | Montpellier, France | Biometrics and medical writing services |
| Newleos | Boston, MA | Anxiety and substance abuse disorder treatments |
| Fulcrum Genomics | Somerville, MA | Bioinformatic Services |
| InPress Technologies | , | Renamed Alydia Health, Sep 2018 |
| Avontec | , | Gone |
| Adge Pharmaceuticals | , | Not registered in CA May 2023; CEO doesn't list job on LI; Residential address, Apr 2022 |
| Elliquence | Baldwin, NY | Minimally-invasive Surgical Devices |
| Rebexsess Discovery Chemistry | , | Founder, sole employee retired Nov 2017 |
| Paladin Labs | Saint-Laurent, QC | Small Molecules |
| Bioimics | , | Website down Apr 2022 - Jul 2022; aka Nanogap |
| MC2 Therapeutics | Hørsholm, Denmark | Topical Delivery Platform |
| LyoTechnica | , | Gone |
| , | Renamed Tacit Therapeutics, Jul 2022 | |
| EAG Laboratories | Liverpool, NY | Analytical & Synthesis Services |
| Mablink Bioscience | , | Acquired by Eli Lilly, Dec 2023 |
| Algeta | , | Acquired by Bayer, Mar 2014 |
| Activaero | , | Bought by Vectura, €130M, Mar 2014 |
| Cervel Neurotech | , | Technology Acquired by Rio Grande Neurosciences, Oct 2015 |
| Atoll | , | Acquired by Repligen, Apr 2016, $9.1M cash + stock |
| Caravan Biologix | Princeton, NJ | CAR T Cell Therapy |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Amylyx Pharmaceuticals | Cambridge, MA | Combination of existing products |
| Bioven | , | Renamed In3Bio, Jul 2020 |
| AtriCure | Pleasanton, CA | Cardiovascular Devices |
| Mariana Oncology | Watertown, MA | Radiopharmaceuticals Targeting Cancer |
| Addiction Therapies | , | Renamed Recovery Pharmaceuticals, Dec 2002 |
| Advinus Therapeutics | , | Renamed Eurofins Advinus |
| Bradley Pharmaceuticals | , | Merged with Nycomed, Feb 2008 |
| BeVivo | , | Website down Feb 2021 - Aug 2021 |
| JenaValve | Leeds, UK | Transcatheter aortic valve replacement system |
| STEMCELL Technologies | Vancouver, BC | Cellular Products |
| Vernay | Yellow Springs, OH | Fluid Control Solutions |
| , | Acquired by Venus Medtech, Dec 2021 | |
| Cell IDx | , | Acquired by Leica Biosystems, Nov 2022 |
| Arginetix | , | Merged with Immune Control to become Corridor Pharmaceuticals, Jun 2010 |
| Aquahug Technologies | , | Website down, Aug 2015 - Gone |
| Boan Biotech | Yantai, China | Biosimilar Antibodies |
| DSM Pharmaceutical Products | , | Merged into a joint venture with Patheon |
| Osteros Biomedica | , | No website Jan 2020 - Dec 2020 |
| Carmell Corporation | , | Merged with Axolotl Biologix, Aug 2023; fka Carmell Therapeutics |
| Trident Lifeline | Surat, India | Generics |
| Genelabs Technologies | , | Acquired by GSK, Oct 2008, $57M |
| Cadent Therapeutics | , | Acquired by Novartis, Dec 2020, $210M + $560M milestones; fka Luc Therapeutics |
| Yantai LNC Biotechnology | Yantai, China | Radiotheranostics |
| Telephus Medical | , | Now Telephus Biosciences |
| XenoBiotic Laboratories | , | Acquired by WuXi Apptec, Oct 2011 |
| Novonesis | Davis, CA | Enzymes, Biologic Reagents |
| Advaxis | , | Merged with Ayala Pharmaceuticals, Jan 2023 |
| Altea Therapeutics | , | All assets acquired by Nitto Denko, Apr 2012 |
| Bio-Cancer Treatment International | , | No news 2019 - Jan 2025 |
| Galatea Surgical | Lexington, MA | Surgical Scaffolds |
| Suvoda | Portland, OR | Clinical Trial Software |
| Roche | Schlieren, Switzerland | Small Molecules |
| ApaTech | , | Acquired by Baxter, Mar 2010, $330M |
| GSK | Hamilton, MT | Vaccine additive |
| Xeris Pharmaceuticals | , | Renamed Xeris Biopharma, Oct 2021 |
| Crystax Pharmaceuticals | , | Acquired by Oryzon Genomics, Mar 2009 |
| Symogen | New Delhi, India | Pharmacovigilance, pharmacoepidemiology, medical writing, and regulatory affairs services |
| Attogene | Austin, TX | Rapid Diagnostics |
| Medspira | Minneapolis, MN | Anorectal Manometry |
| Boston Biotech Clinical Research | Cambridge, MA | Clinical Consulting |
| Pfizer Animal Health | , | Spun off, Renamed Zoetis Jul 2013 |
| Sentien Biotechnologies | , | Shut down late 2021 |
| iuvo BioScience | Costa Mesa, CA | Ophthalmic Clinical Research Services |
| Cannabics | , | Renamed CNBX Pharmaceuticals, Mar 2022 |
| CS Bio | Shanghai, China | Peptide Synthesizers & Custom Synthesis |
| Cynapsus Therapeutics | , | Acquired by Sunovion, Oct 2016, $635M |
| AllerGuard | , | Website gone Sep 2022 - Feb 2023 |
| Valor Biotechnology | , | Renamed Roivant |
| BioNTech | Mainz, Germany | mRNA, Vaccines, Biologics |
| Innara Health | , | Acquired by Cardinal Health, Apr 2022 |
| OverT Bio | New York, NY | Cell Therapy |
| Advanced Technology and Regenerative Medicine | , | Bought by DePuy |
| Laminar | , | Acquired by Johnson & Johnson, Nov 2023, $400M |
| Hesperos | Orlando, FL | Human-on-a-chip |
| PolyPid | Petach Tikva, Israel | Polymer lipid encapsulation matrix |
| Novotech | Shanghai, China | Clinical Research |
| Famar | Athens, Greece | Contract Manufacturing - Small Molecules |
| MLM Medical Labs | Memphis, TN | Clinical Lab |
| Agno Pharma | Suzhou, China | Small molecule CRO, CDMO |
| AB Sciex | , | Renamed Sciex |
| PathoGenetix | , | Bankrupt Jul 2014, ceased operations, terminated almost all employees |
| Znomics | , | Bankrupt, Shell Company Now |
| Asta Pharmaceuticals | , | Website down Oct 2020 - Feb 2021 |
| Novahep | , | Website down, Oct-Dec 2017 |
| Azad Pharma | Montreal, QC | APIs, generics |
| Ketal Biomedical | , | Gone |
| Embera NeuroTherapeutics | , | Employees all gone, Jul 2024 |
| Genova Clinical Research | , | Gone, 2014 |
| Protagen Protein Services | , | Merged with BioAnalytix, Apr 2019 |
| CROMSOURCE | Cary, NC | Clinical Research, Consulting |
| Xytos | , | Accused by SEC of being a sham. Probably is. |
| Vernalis Research | Cambridge, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Amicus Therapeutics | Philadelphia, PA | Small Molecules |
| NovaScreen Biosciences | , | Acquired by Caliper Life Sciences, Oct 2005, $22M |
| AirXpanders | , | Filing Chapter 7 Bankruptcy, Jul 2019 |
| Curogen | Suwon, Korea | Autoimmune Therapies. Small Molecules, Soluble Fusion Proteins |
| SmartCells | , | Bought by Merck Dec 2010 |
| , | Website down Jan 2026 - May 2026; fka Ativa Medical | |
| WIL Research | , | Bought by Charles River, Apr 2016, $585M |
| Accel Biotech | , | Acquired by Ximedica, Jul 2016 |
| , | Merged with Mallinckrodt, Nov 2025 to become Keenova/Par Health | |
| Wolfe Laboratories | , | Acquired by Pace Analytical, Dec 2017 |
| Labyrinth BioPharma | Bloomington, IN | Formulation, analytical, and lyophilization cycle development of small and large molecules, suspensions, emulsions, and diagnostic products |
| Tiziana Life Sciences | London, UK | Oncology Therapies |
| Genuine Biosystem | Chennai, India | IVD Products |
| AC Immune | Lausanne, Switzerland | Alzheimer's Treatments |
| Pharma Medica | Toronto, ON | Clinical Services |
| Bionter | , | Company presumed shut down Mar 2025; Website down Dec 2024 - Mar 2025 |
| Novelstar Pharmaceuticals | , | Website Down Feb 2025 |
| Sycai Medical | Barcelona, Spain | Automate the detection and surveillance of lesions in the abdomen |
| Evopoint Biosciences | Concord, MA | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Heraeus Medical | Minneapolis, MN | Medical Devices |
| Johari Medtech | Jodhpur, India | Medical Devices |
| Lifelines Neuro | Louisville, KY | EEG Systems |
| TigaTx | , | Acquired by Epsilogen, Apr 2025 |
| CellXplore | , | Gone |
| Hancock Jaffe Laboratories | , | Renamed enVVeno, Sep 2021 |
| Impax Pharmaceuticals | , | Merged with Global Pharmaceuticals to become Impax Laboratories, Dec 1999 |
| Inpharmus | Istanbul, Turkey | Small Molecules? |
| Cell2B | , | Possibly reincarnated as StemCell2MAX |
| Nordic Pharma | Hoofddorp, Netherlands | Specialty Pharmaceuticals, Diagnostic, hyaluronic acid |
| ArisGen | , | Only employee has four other jobs |
| MedTech Bioscience | , | Website gone Sep 2017 |
| Precision Healing | , | Acquired by Sanara MedTech, Apr 2022 |
| OrthoSpin | , | Acquired by Depuy Synthes, Dec 2021 |
| EMIT Imaging | Natick, MA | Cryo-Fluorescence Tomography |
| Aromics | Barcelona, Spain | Therapeutics & Diagnostics |
| Smith Therapeutics | , | Acquired by AZTherapies, Oct 2019 |
| Parthenon Therapeutics | , | Renamed Incendia Therapeutics, Aug 2023 |
| Rigontec | , | Bought by Merck, Sep 2017, $150M + $453 Milestones |
| Celerion | Zurich, Switzerland | Clinical Research |
| ProCyte | , | Acquired by PhotoMedex, Mar 2005 |
| WibiWorks Therapeutics | , | Changed name to Commence Bio, Jan 2016 |
| Axiogenesis | , | Merged with Plurinomics to form Ncardia, Sep 2017 |
| Vineti | , | Website down Jun 2023 - Dec 2023; GE Ventures spinout |
| Xencor | San Diego, CA | Antibody Discovery |
| Counsyl | , | Acquired by Myriad Genetics, Aug 2018 |
| Roche | Singapore, Singapore | Small Molecules & Diagnostics |
| Roxwood Medical | , | Acquired by BTG plc, Oct 2017 |
| Bionano Genomics | San Diego, CA | Genome Mapping |
| Getinge | Orléans, France | Medical Technology |
| Teleflex Medical | Greenstone, South Africa | Surgical and Medical Devices |
| OrthoNovis | Palm Coast, FL | Trauma, Biologic Devices |
| CollPlant Biotechnologies | Rehovot, Israel | 3D Bioprinting, Orthobiologics, Wound Healing |
| HUMAN Diagnostics | Magdeburg, Germany | Lab Diagnostic Products |
| Syntex Pharmaceuticals | , | Became part of Roche in 1994 |
| IDAC Theranostics | , | Website copyright 2012 as of 2021, no info |
| |
Boothwyn, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Japan BCG Laboratory | , | No news 2020 - May 2025 |
| Zai Lab | Shanghai, China | Small Molecules |
| Cirtec Medical | Enfield, CT | Contract Medical Devices |
| ARTham Therapeutics | , | Shut Down late 2023 |
| AimMax Therapeutics | Durham, NC | Biopharmaceuticals |
| Teleflex Medical | Athlone, Ireland | Surgical and Medical Devices |
| Fluke Biomedical | Everett, WA | Wide range of medical devices |
| NovaRx | , | Changed name to Activate Immunotherapy, Aug 2016 |
| Kamat Pharmatech | , | Website down Oct 2021 - Jul 2022 |
| Exemplar Pharma | , | Website gone Apr 2014; Contracted by Allergan to manufacture a product and FDA had a problem with it (2013) |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
| Ileo Science | , | Seems gone Mar 2022 |
| Plectix Biosystems | , | Shut Down, Jun 2010 |
| ACEA Biosciences | , | Acquired by Agilent, Nov 2018 |
| Helix3 | Morrisville, NC | Contract Research Lab |
| Xios Therapeutics | , | Website down Feb 2021 - Jul 2021 |
| Rodelis Therapeutics | , | Were going to acquire drug and jack the price up, but decided not to in face of Shkreli outrage |
| Proteina | , | Website down Mar 2023 - Apr 2024 |
| Innerpulse | , | Gone maybe 2013 |
| Heraeus Medical | Hanau, Germany | Medical Devices |
| Evexta Bio | Paris, France | Trans CD4 Immunotherapy |
| GenMark Diagnostics | , | Acquired by Roche, May 2021, $1.85B |
| , | Shut down Feb 2026 | |
| Regenerative Sciences | , | Took on Regenexx product name |
| X7 Research | , | Website hijacked Feb 2025 |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| PreventAGE Health Care | , | fka Journey Biosciences |
| , | Renamed Indero | |
| Socium Therapeutics | , | Website down Jun 2023 - Dec 2023; Founders are two patent attorneys |
| Cerveau Technologies | , | Acquired by Lantheus, Feb 2023 |
| Worldwide Clinical Trials | Berlin, Germany | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Sosei Group | , | Renamed Nxera Pharma, Apr 2024 |
| Pharmaforce | , | Renamed American Regent, Jan 2019; Bought by Luitpold Jan 2010 |
 |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| TissueTech | , | Took parent company name, BioTissue, Jun 2022 |
| Bayon Therapeutics | , | Acquired by EyeGate Pharmaceuticals, Oct 2021 |
| Cypress Bioscience | , | Acquired by Royalty Pharma |
| Islet Sciences | , | Gone |
| Spinnaker Biosciences | , | Filings two years late Feb 2024; Active in 2020 in spite of website appearance |
| Advanced Medicine Partners | , | Website down Mar 2025 - Aug 2025 |
| LBT Innovations | , | Renamed Clever Culture Systems, Nov 2024 |
| Centinel Spine | West Chester, PA | Spinal Implants |
| Nicoya Lifesciences | Kitchener, ON | Benchtop Surface-Plasmon Resonance |
| Healeon Medical | , | Acquired by Bimini HealthTech, Jun 2020 |
| Purolite Chromatography Services | , | Acquired by Ecolab, Oct 2021, $3.7B |
| Generon | , | Renamed Evive Biotech, Jun 2020 |
| Salus Bioscience | , | Forfeited in CA |
| Glen Research | Sterling, VA | Oligos |
| Afferent Pharmaceuticals | , | Bought by Merck, Jul 2016, $1.25B |
| Yokogawa | Newnan, GA | Cell Analysis, Biological Containment, Equipment |
| AstraZeneca | Gothenburg, Sweden | Small Molecules, Vaccines, Biologics |
| Genphar | , | Owner Indicted by Feds for fraud. Building foreclosed Sep 2013 |
| Tasly Pharmaceutical | Tianjin, China | Small Molecules, Generics |
| Hemay Pharmaceutical | Tianjin, China | |
| Hyperfine | Guilford, CT | Portable MRI Scanner |
| Genomics Collaborative | , | Acquired by BioServe, 2007 |
| Devsynthesis | Austin, TX | Chemistry CRO |
| Nortis | , | Acquired by Quris-AI, Oct 2024 |
| Pinetree Therapeutics (1) | , | Shut down 2018 |
| SpinalMotion | , | Website gone, 11-30-14 |
| Mabylon | Schlieren, Switzerland | Antibody Discovery |
| NeuroKaire | Tel Aviv, Israel | Depression Diagnostics |
| Kuano | Cambridge, UK | AI Drug Discovery |
| Arjo | Hoffman Estates, IL | Therapeutic Support Systems for immobile people |
| Roche | Basel, Switzerland | Diagnostics |
| ZielBio | , | Website down Jul 2024 - Dec 2024 |
| Dalex Biotech | , | Gone |
| BioFactura | Frederick, MD | Biosimilar production technology, smallpox drug |
| Arkis Biosciences | , | Acquired by Integra LifeSciences, Jul 2019 |
| Evorion Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Pinta Biotherapeutics | , | Believe they were folded back into Atara or shut down entirely |
| Imagen Therapeutics | , | Liquidated Apr 2023 |
| MedPharm | Guildford, UK | MedPharm is the world’s leading contract provider of topical and transdermal product design and formulation development services |
| Abveris | , | Acquired by Twist Bioscience, Nov 2021, $150M + $40M milestones; fka AbX Biologics |
| SQN Clinical | , | Acquired by Veristat, Feb 2021 |
| Watson Pharmaceuticals | , | Acquired Actavis, Oct 2012, took their name |
| Angiex | Cambridge, MA | Antibody-Based Therapeutics |
| Apalexo Biotechnologie | , | No info, probably gone |
| Quanta Therapeutics | South SF, CA | Small Molecules Targeting RAS-driven Cancers |
| ADispell | , | Website gone Apr 2018 |
| Fosun Pharma | Shanghai, China | Small molecules, diagnostics, traditional |
| Azena Medical | Walnut Creek, CA | Pretty medical devices |
| Allorion Therapeutics | Natick, MA | Small molecule drugs against cancer and autoimmune diseases |
| Pharma Dynamics | Cape Town, South Africa | Generics |
| Aaren Scientific | , | Bought by Zeiss, Jan 2014 |
| BTG plc | , | Acquired by Boston Scientific, Aug 2019, $4.3B |
| Ossur | Reykjavik, Iceland | Orthopedic Devices |
| Xenotech | , | Acquired by BioIVT, Sep 2022; fka Xenotech |
| |
East Chicago, IN | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| Stiefel | , | Acquired by GSK |
| United Pharmaceutical | Fullerton, CA | Softgel Manufacturing |
| Adarza Biosystems | , | Website down May 2022 - Oct 2022 |
| Avalo Therapeutics | Wayne, PA | Small molecules for neuro / psychiatric disorders |
| Sensus Healthcare | Tel Aviv, Israel | Superficial Radiation Therapy |
| TE Connectivity | Medway, MA | Catheter manufacturing & development |
| InvivoSciences | Madison, WI | 3D Human Micro Tissues for Drug Discovery and Development |
| BDR Pharmaceuticals | Vadodara , India | APIs, New Age Formulations |
| Provista Diagnostics | , | Acquired by Todos Medical Apr 2021; Acquired by Ascenda BioSciences, Jun 2019 |
| Ansan Pharmaceuticals | , | Acquired by Discovery Labs, Jul 1997 |
| BioAI Health | Manchester, NH | AI Biomarker Services |
| Argolight | Pessac, France | Microscopes |
| Cellscope | , | Website down Aug 2019 - Oct 2019 |
| Viking Therapeutics | San Diego, CA | Therapeutics for metabolic and endocrine disorders |
| , | Website down Nov 2025 - Apr 2026 | |
| Bioinformatics Consultants | , | Website down Dec 2022 - Apr 2023 |
| Precison Immune | , | Renamed Pionyr Therapeutics |
| Target Medicals | , | No news 2016 - Oct 2024 |
| AltheRx Pharmaceuticals | , | Effectively renamed Velicept Therapeutics Jun 2015. Technically, Velicept was created then merged into AltheRx |
| InfraReDx | Bedford , MA | Medical Devices |
| RaySearch Laboratories | Santa Clara, CA | Cancer Research Software |
| ViraCyte | , | Renamed AlloVir |
| Novo Nordisk | Køge, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| ArunA Biomedical | , | |
| Trillium Therapeutics | , | Acquired by Pfizer, Nov 2021, $2.3B |
| ndd Medical Technologies | Andover, MA | Lung Diagnostics Devices |
| DDi | Basel, Switzerland | Clinical Software |
| Cello Health | , | Renamed Lumanity, Mar 2022 |
| Aviceda Therapeutics | Cambridge, MA | Next generation of glyco-immune therapeutics |
| Med Investigations | , | Website down Oct 2021 - Jul 2022 |
| Primorigen Biosciences | , | Acquired by Nucleus Biologics, Aug 2019 |
| E-nitiate Biopharmaceuticals | Hangzhou, China | Small Molecules |
| Tillotts Pharma | Rheinfelden, Switzerland | Small Molecules, Specialty Pharma |
| Synthace | London, UK | Development Software |
| Affera | , | Acquired by Medtronic, Sep 2022, $1B |
| Healogix | Doylestown, PA | Consulting |
| Dynogen | , | Bankrupt, seemingly winding down slowly |
| Exopharm | , | Acquired Tryp Therapeutics, May 2024, took name Tryptamine Therapeutics |
| Wishbone Medical | Warsaw, IN | Pediatric orthopedic |
| NeuClone | Sydney, Australia | Biosimilars |
| Nine Square Therapeutics | South SF, CA | Small Molecules for Neuro |
| SentreHEART | , | Bought by AtriCure, Aug 2019, $300M |
| Acris Pharmaceuticals | , | Dissolved. 2015? |
| Recipharm | Solna, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| NeuroTherapeutics | , | Gone |
| Maccura Biotechnology | Chengdu, China | Lab Equipment, Analyzers |
| Emergence Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $470M + $335M milestones |
| Ardena | Ghent, Belgium | Enhancing Solubility via Formulation Development |
| Prometheus Biosciences | , | Acquired by Merck, Jun 2023, $11B; fka Precision IBD, took Prometheus Biosciences name after buying Prometheus Laboratories from Nestle, Jun 2019 |
| Simcere Pharmaceutical Group | Nanjing, China | Small Molecules |
| Epsilon Molecular Engineering | Saitama, Japan | Heavy chain single domain antibodies |
| F2G | Cheshire, UK | Antifungals |
| Resolve Biosciences | Monheim, Germany | Molecular Cartography |
| BGI | Copenhagen, Denmark | Diagnostics |
| , | Website down Sep 2025 - Dec 2025 | |
| , | Acquired by EPI, Mar 2022 | |
| Scienion | , | Renamed Cellenion Aug 2021; Acquired by CELLINK, Aug 2020, €80M |
| VaxGen | , | Acquired by diaDexus, Jul 2010 |
| Pharmacore | , | Acquired by Cambrex, Sep 2016, $25M |
| Huya Bioscience | San Diego, CA | Compound Advancement |
| Cook Pharmica | , | Bought by Catalent, Oct 2017 |
| Atlantic Pharmaceuticals | , | Dated website, uses flash |
| Sancilio Pharmaceuticals | , | Bankrupt, out of business May 2019, some assets bought by Micell Biopharma |
| Detectogen | , | Marked as closed on Google, Nov 2019 |
| Tragara Pharmaceuticals | , | Renamed Adastra Pharmaceuticals, Jan 2019 |
| Spotlight Innovation | , | Shell Company, Dec 2019 |
| MedSource | , | Acquired by Ergomed, Dec 2020, $18M |
| Acceleron Pharma | , | Acquired by Merck, Nov 2021, $11.5B |
| BrainQ | Jerusalem, Israel | AI-powered, non-invasive wearable device delivering frequency-tuned electromagnetic field therapy |
| EXACT Therapeutics | Oslo, Norway | Ultrasound for Enhanced Drug Delivery |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Quantum Surgical | Montpellier, France | Tumor Ablation Robot |
| Emerald Clinical Trials | Sydney, Australia | CRO providing a full range of trial management services. |
| Alphalyse | Odense, Denmark | Protein Characterization Services |
| MicroPort | Shanghai, China | Medical Devices |
| Baylis Medical | , | Acquired by Boston Scientific, Feb 2022, $1.75B |
| RxCelerate | Cambridge, UK | Contract Services |
| Cetylite Industries | Pennsauken, NJ | Topical anesthetics |
| , | Pivoted to Crypto, Oct 2025 | |
| Neurocentria | Walnut Creek, CA | Small molecule for neurological disorders |
| Shields Pharma | Markham, ON | Psychedelic analytical testing and Contract testing lab |
| PolyRemedy | , | Switched to Cosmetics, trying to sell company Jun 2016 |
| Jiuzhou Pharma | Linhai, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Cellerant Therapeutics | , | Website down Oct 2021 - Jan 2022; President gone mid 2021 |
| Gloria Biosciences | Guangzhou, China | Monoclonal Antibody |
| Quick-Med Technologies | , | Website down Jan 2024 - Aug 2024 |
| Nonacus | Birmingham, UK | Cell-free DNA Analysis |
| i2 Pharmaceuticals | , | Website down Oct 2021 - Dec 2022 |
| FFE Therapeutics | , | Shut down Dec 2013 |
| Biora Therapeutics | San Diego, CA | Oral Biotherapeutics for GI Health |
| Nerio Therapeutics | , | Acquired by Boehringer Ingelheim, Jul 2024, $1.3B |
| bioTheranostics | , | Acquired by Hologic, Feb 2021, $230M; bought by bioMérieux 2008, spun out again Jan 2016 |
| CS Bio | Mumbai, India | Peptide Synthesizers & Custom Synthesis |
| Hemanext | Lexington, MA | Transfusion Technologies |
| , | Renamed Verge Medical, Mar 2025 | |
| Recipharm | Monts, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Myst Therapeutics | , | Acquired by Turnstone Biologics, Jan 2021 |
| Dilaforette | , | Changed name to Modus Therapeutics, Oct 2016 |
| Pulmokine | , | Acquired by XOMA Royalty, Nov 2024; Website hijacked and no news since 2013 as of Jul 2022 |
| Mnemosyne Pharmaceuticals | , | Changed name to Luc Therapeutics, Oct 2015 |
| TRIFARMA | Chennai, India | APIs |
| Igenica Biotherapeutics | , | Assets acquired by Pierre Fabry, May 2017 |
| Hybrid Biosystems | , | Merged with Myotec Therapeutics to become PsiOxus Therapeutics, Dec 2010 |
| Threshold Pharmaceuticals | , | Merged into Molecular Templates, Aug 2017 |
| Opus Regulatory | Boston, MA | Regulatory Consulting |
| SeaChange Pharmaceuticals | , | Shut down 2020 |
| Wings Therapeutics | , | Website down May 2021 - Oct 2021; Spun out of ProQR, Mar 2019 |
| Leading Pharma | Fairfield, NJ | Generics |
| Originus | , | Gone |
| MedChemExpress | Monmouth Junction, NJ | Compound Library, Lab Reagents, Services |
| AGC Biologics | Bresso, Italy | Contract Manufacturing - Biologics |
| MaganaMed | Regensburg, Germany | Data Capture Software |
| Reckitt Benckiser Pharmaceutical | Parsippany, NJ | OTC / Consumer Brands |
| , | Website down Sep 2025 - Feb 2026 | |
| Sanvitra | , | Website down Apr 2023 - Sep 2023 |
| Biovico | Gdynia, Poland | Biotech and Pharma Products |
| Cobalt Biomedicine | , | Merged with Sana Biotechnology, early 2019 |
| BSD Medical | , | Renamed Perseon Medical, Feb 2015 |
| Piramal | Ennore, India | CDMO |
| Cellink | Gothenburg, Sweden | Bioprinting |
| |
Athens, Greece | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| StageZero Life Sciences | Richmond Hill, ON | Diagnostics and personalized medicine |
| Onxeo | , | Renamed Valerio Therapeutics, Jun 2023 |
| DiagnoSearch | Thane, India | Clinical Research |
| Zenflow | South SF, CA | Device to alleviate obstructed urinary tract |
| , | No news 2019 - Apr 2026 | |
| BiOM | , | Now BionX Medical |
| Telik | , | Merged with MabVax Jul 2014, company originally maintained Telik's ticker, then switched it in Oct 2014 |
| Accumedix | Libertyville, IL | Medical Device Commercialization |
| Amniox Medical | , | Folded into BioTissue |
| Delinia | , | Bought by Celgene, Jan 2017, $300M + $475 milestones |
| , | Inactive May 2025 | |
| Metabolomic Diagnostics | Little Island, Ireland | Pre-eclampsia diagnostic |
| Translational Bioscience | , | |
| Sava Healthcare | Wadhawan, India | Generic Formulations |
| Vernacare | Worksop, UK | Surgical Devices |
| Mimetas | Oegstgeest, Netherlands | Organ-on-a-Chip |
| Vernacare | Newtown, UK | Surgical Devices |
| AVROBIO | , | Merged with Tectonic Therapeutics, Jun 2024 |
| iRiva Medical | Minneapolis, MN | Next generation neuromodulation technology |
| Vigilant Biosciences | Lakeway, TX | Cancer detection |
| Coating Place | Verona, WI | Drug Delivery Services |
| Fuse Diagnostics | New York, NY | Molecular Diagnostics |
| Anchen Pharmaceuticals | , | Acquired by Par Pharmaceutical, Aug 2011 |
| OXYVITA | , | Website down Feb 2022 - Jun 2022 |
| Genyous Biomedical International | , | Presumed Gone |
| Charles River Laboratories | Beijing, China | Research Animal Models and Preclinical Research |
| Labcorp Clinical Trials | , | folded into LabCorp proper? |
| APAC Biotech | Haryana, India | Immunocellular Therapy |
| CellforCure | Les Ulis, France | CDMO for Cell and Gene Therapies |
| |
Poznań, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| BSN Medical | , | Acquired by Essity, Apr 2017 |
| Leonardo Biosystems | , | Website gone Jul 2015 |
| Eurocine Vaccines | , | Acquired for Ticker, Sep 2024 |
| RainBIO | , | Merged into CalciMedica, Feb 2025 |
| Mundipharma | Cambridge, UK | Filing in additional markets |
| BioVex | , | Bought by Amgen, Jan 2011, $425M + $575M milestones |
| Glauconix | , | Renamed Humonix Biosciences, Jul 2023 |
| Vision Medicines | , | Gone 2017 |
| RMC Pharmaceutical Solutions | , | Acquired by Syner-G BioPharma Group, Jan 2023 |
| Rhapsody Biologics | , | Management page 5+ years out of date. No employees on LI |
| Spaulding Clinical Research | West Bend, WI | Early Stage Clinical Research |
| Argyle Therapeutics | , | Spinout of Signum Biosciences 2011, Renamed Signum Dermalogix |
| Cellix Biosciences | , | Website down Feb 2025 - Jul 2025 |
| Genomica | , | Shut down Sep 2022 |
| |
Boston, MA | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| MorphoSys | , | Acquired by Novartis, Feb 2024, $2.9B |
| Proove Biosciences | , | Sold Assets, Shut down Aug 2017 |
| Merix Bioscience | , | Renamed Dendrix |
| ProQR Therapeutics | Cambridge, MA | Oligonucleotide Therapy |
| BioMimetics Sympathies | Tokyo, Japan | Stem cells for research, cell culture technology |
| GD Searle | , | Acquired by Monsanto 1985, Merged into Pharmacia, name retired in 2003 after Pfizer acquisition |
| CTC | Uppsala, Sweden | Clinical Site Network |
| Novocell | , | Renamed Viacyte |
| Oscor | , | Acquired by Integer, Dec 2021 |
| Carma Therapeutics | , | Renamed Carisma Therapeutics, 2018 |
| Pyramid Biosciences | , | Website down Feb 2024 - Jul 2024 |
| Alamo Pharma Services | , | Website Down Jan 2022 - Feb 2022 |
| Theradaptive | Frederick, MD | Protein-engineering Technology |
| Constantiam Bio | Houston, TX | Clinical Interpretation Software |
| TandemAI | New York, NY | AI to democratize the drug development process |
| Wondercel Therapeutics | Shenzhen, China | CAR T |
| ClinTrek Research | Bangalore, India | Clinical Research & Services |
| DOV Pharmaceuticals | , | Acquired by Euthymics |
| Paraza Pharma | Montréal, QC | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| ARMO BioSciences | , | Acquired by Lilly, Jul 2018, $1.6B |
| Xtal BioStructures | , | Acquired by Schrödinger, Jan 2022, $6M |
| Deltanoid Pharmaceuticals | , | Website gone, Mar 2019 |
| Micro Systems Engineering | Lake Oswego, OR | Medical microelectronics development & design, system integration, and manufacturing |
| Riverpoint Medical | Portland, OR | Medical Device Manufacturing |
| AccuVein | Medford, NY | Vein Visualization |
| Bicycle Therapeutics | Cambridge, UK | Peptides |
| BioPharm Informatics | , | Renamed LabCentrix, Feb 2007 |
| TRiNDS | Pittsburgh, PA | Clinical Research for neuromuscular diseases |
| Daiichi Sankyo | Odawara, Japan | Small Molecules |
| Integrity Bio / LyoTip | , | Acquired by Curia, Jul 2021 |
| ALZA | , | Bought by J&J, Jun 2001, $11.8B stock |
| Sirius Analytical | , | Acquired by pion, May 2017 |
| Vivet Therapeutics | Paris, France | Gene Therapy for Orphan Diseases |
| Xellar Biosystems | Boston, MA | Organ-on-a-Chip |
| NatiMab Therapeutics | , | Website gone Jun 2023 - Sep 2023 |
| Drais Pharmaceuticals | , | Website taken over Feb 2022 |
| Niramai | Bengalaru, India | AI-breast cancer detection device |
| Quantificare | Maringa, Brazil | Medical Imaging |
| Curefaktor Pharmaceuticals | , | Website Gone |
| NovaMed Pharmaceuticals | Lahore, Pakistan | Small Molecules |
| Catalent | Bloomington, IN | Biologics Manufacturing & Cell Line Development |
| 7D Surgical | , | Part of Orthofix; Acquired by SeaSpine, Mar 2021, $82.5M |
| Velocity Clinical Research | Durham, NC | Clinical Research Organization |
| AssureRx | , | Renamed Assurex Health |
| Factorial Diagnostics | , | Renamed Factorial Biotechnologies |
| Jiuzhou Pharma | Suzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| D-Kimia | , | Website down Feb 2025; Latest news 2013 - as of 2021 |
| Optime Therapeutics | , | Acquired by Lippomix |
| Elanex Pharmaceuticals | , | Gone |
| Altasciences | Everett, WA | Contract Research |
| Theracos | , | Renamed TheracosBio |
| Integrated DNA Technologies | Coralville, IA | Nucleic Acid Synthesis |
| EUROIMMUN | Lübeck, Germany | Lab Assays |
| Lodestone Biomedical | Lebanon, NH | In Vivo Biomarker Monitoring |
| Unnatural Products | Santa Cruz, CA | Macrocylic Peptides plus AI |
| Curiox Biosystems | Singapore , Singapore | Assay Platform |
| Mologic | , | Acquired by Gates & Soros and turned into nonprofit |
| CoSara Diagnostics | Ranoli, India | Molecular Diagnostics |
| Revalia Bio | New Haven, CT | Organ Preservation Technology and Delivery |
| Abilitech Medical | , | Website down Sep 2023 - Mar 2024 |
| Evrys Bio | Doylestown, PA | Antivirals targeting non-viral human proteins |
| Dantari Pharmaceuticals | , | Shut down Aug 2024; Website down Jul 2024 - Dec 2024 |
| Neuravi | , | Acquired by J&J, Apr 2017 - Became part of Cerenovus |
| Ximedica | San Francisco, CA | Medical Device Services |
| Alpha Genesis | Yemassee, SC | Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services |
| Andrx Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Nov 2006, $1.9B |
| Neurescence | , | Acquired by Bruker, Dec 2022 |
| Implen | Munich, Germany | Spectroscopy instruments and consumables for the non-destructive analysis of ultra low volume samples |
| Euthymics Biosciences | , | Assets acquired by Ethismos Research, Nov 2017 |
| Pronovo Biopharma | , | Bought by BASF, Nov 2012, $844M |
| LifeCycle Pharma | , | Lundbeck spinoff, Changed name to Veloxis Pharmaceuticals Jul 2011 |
| Lohmann Animal Health International | , | Acquired by Elanco, Feb 2014 |
| Signature Diagnostics | Pittsburgh, PA | Noninvasive Diagnostics |
| Tarveda Therapeutics | , | Gone, Oct 2022 |
| Copernicus Therapeutics | , | Website gone Aug 2022 - Jan 2023; fka Copernicus Gene Systems |
| , | Website down Oct 2025 - Jan 2026 | |
| Ataia Medical | , | Website taken over Jan 2024 |
| Curatek Pharmaceuticals | , | Website gone Mar 2024; LI page gone Nov 2023 |
| Sensus Healthcare | Boca Raton, FL | Superficial Radiation Therapy |
| MyCellHub | Hasselt, Belgium | Digital batch records, data management platform, analytics platform |
| Samjin Pharm | Seoul, Korea | Small Molecules |
| 3DHISTECH | Budapest, Hungary | Pathology Software, Hardware & Services |
| Casebia Therapeutics | , | Joint venture of Bayer & CRISPR Therapeutics, folded into CRISPR late 2019 |
| |
Waltham, MA | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Praxis BioSciences | , | Website down, Dec 2022 - Sep 2023 |
| ERT | , | Renamed Clario, Nov 2021 |
| LSK Global Pharma Services | Seoul, Korea | Clinical Research |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| Autocam Medical | Murfreesboro, TN | Precision-Machined Medical Devices, Implants |
| Talapo Therapeutics | , | Website gone, Dec 2019 |
| Valtari Bio | , | Website down Mar 2023 - Sep 2023; fka CereDx |
| Conformis | , | |
| Olaregen Therapeutix | , | Maintenance Mode Apr 2023 - Jul 2023; Employees all gone from Linkedin |
| Acthera | , | Website down Feb 2024 - Jul 2024 |
| Citron Pharma | , | Assets acquired by Rising Pharmaceuticals, Dec 2016 |
| PanOptica | , | Website down Oct 2024 - May 2025 |
| Biomillenia | , | Website down Jun 2024 - Nov 2024 |
| XNK Therapeutics | , | Bankrupt, Assets sold May 2024 |
| Miach Orthopaedics | Westborough, MA | Knee Orthopedics |
| Touchdown Therapeutics | , | Renamed Affinia Therapeutics |
| CardioEphEx | , | Shut down Dec 2020 |
| Jounce Therapeutics | , | Acquired by Concentra Biosciences, May 2023 |
| Vivid Genomics | , | Shut down Sep 2023 |
| Euveda Biosciences | , | Website gone, Dec 2017, single employee is founder |
| Pfizer | Bothell, WA | Small Molecules, Vaccines, Biologics |
| Silony Medical | , | Renamed Silony Spine, Oct 2023 |
| CBT Pharmaceuticals | , | Renamed Apollomics, Jan 2019 |
| Quellis Biosciences | , | Acquired by Catabasis Pharmaceuticals, Jan 2021 |
| Epithelix Sarl | Geneva, Switzerland | Human-Derived Experimental Tissues |
| LintonPharm | Guangzhou, China | Bispecific Antibodies |
| Ottobock | Nieuwkuijk, Netherlands | Prosthetics |
| Unither Pharmaceuticals | São Paulo, Brazil | CDMO |
| Envisagenics | New York, NY | Software-based drug discovery |
| Focus-X Therapeutics | , | Acquired by Full Life Technologies, Nov 2022, up to $245M |
| Reliable Biopharmaceutical | , | Bought by VWR Nov 2016 |
| iperian | , | Acquired by Bristol-Myers Squibb, Apr 2014, $175M |
| Calcula Technologies | , | Website down Sep 2023 - Dec 2023; CA business filings late Jun 2023 |
| Broncus Medical | San Jose, CA | Virtual Bronchoscopic Navigation, Peripheral Lung Biopsy |
| Juventas Therapeutics | , | CEO moved, Website is single page, Google says closed, Jan 2022 |
| Terremoto Biosciences | South SF, CA | Covalent Small Molecules |
| Solu Therapeutics | Boston, MA | Antibody-drug conjugates |
| Numares Health | Regensburg, Germany | AI-enabled diagnostic tests |
| Endeavor BioMedicines | San Diego, CA | Hedgehog signaling pathway inhibitor |
| Nextgen BioX | , | Website down May 2024 - Jul 2024 |
| Alcediag | Montpellier, France | RNA-based Diagnostics |
| VedTechBio Research | Bangalore, India | Biopharma Consulting |
| Metatstatix | , | Renamed Altiris Pharmaceuticals |
| Blue Note Therapeutics | , | Shut down Apr 2024 |
| ProGDerm | , | Changed to Novare Pharmaceuticals by Allied Minds, Oct 2014 |
| Viatris (2) | Hyderabad, India | Small Molecules |
| StemBioSys | San Antonio, TX | Stem Cells |
| Severn Biotech | Worcestershire, UK | Peptide synthesis |
| Arzeda | Seattle, WA | Computation protein design |
| Immunotech Biopharm | Hong Kong, China | Immunotherapy |
| Frontage | Suzhou, China | Contract Research & Development, Clinical Services, CMC Services |
| Omni Bio Pharmaceutical | , | Shut down May 2015, no money |
| Nubilaria | Novara, Italy | Clinical Data Collection |
| Calcionics | , | Shut down 2010 |
| Reverie Labs | , | Acquired by Ginkgo Bioworks, Feb 2024 |
| IBSA Institut Biochimique | Manno, Switzerland | Various Treatments and Nutraceuticals |
| KAI Pharmaceuticals | , | Bought by Amgen 2012 |
| iTP Biomedica | , | Website down Jul 2019 - Oct 2019 |
| ZyVersa Therapeutics | Weston, FL | Specialty Pharmaceuticals |
| SciClone Pharmaceuticals | Shanghai, China | Small Molecules |
| Apeximmune | Burlingame, CA | Immune oncology mABs |
| BioLeaders | , | Renamed MOA Life Plus, Mar 2024 |
| Polaroid Therapeutics | Schlieren, Switzerland | Antimicrobial Coatings & Therapies |
| Esper Biosciences | , | No info, no website, Nov 2018 - Feb 2024 |
| Rose Biosciences | , | Website down Nov 2024 - Apr 2025; No info Nov 2022 - Feb 2023, one page website |
| ACON Laboratories | San Diego, CA | Diagnostics & Devices |
| Xcede Technologies | , | Gone Jun 2020 |
| Lightlake Therapeutics | , | Changed name to Opiant Pharmaceuticals, Feb 2016 |
| BJ Bioscience | , | Website down Jun 2024 - Nov 2024 |
| Kentucky Bioprocessing | , | Now Kbio |
| Aphena Pharma Solutions | Cookeville, TN | Pharmaceutical Packaging |
| Laboratorios Farmaceuticos Rovi | Madrid, Spain | Biosimilars, Contract Manufacturing, Licensed Products |
| Curis | Lexington, MA | Small Molecules |
| Viridian Therapeutics | Boulder, CO | Monoclonal Antibodies, Fc Fragments |
| Nucleai | Tel Aviv, Israel | AI-powered Tumor Micro Environment modeling |
| Arteaus Therapeutics | , | Product re-acquired by Eli Lilly, Jan 2014, Site gone, owners sold off royalty stream |
| Cytoplex Biosciences | , | Gone |
| Veniti | , | Acquired by Boston Scientific, Aug 2018, $108M + milestones (already owned 25%) |
| Norac Pharma | Azusa, CA | API Manufacturing |
| Dendritix | , | Renamed Argos Therapeutics |
| Niowave | Lansing, MI | Radioisotopes |
| BioSistemika | Ljubljana, Slovenia | IT and related services |
| Quotient Therapeutics | Cambridge, MA | Genetic Library |
| Exact Sciences | Madison, WI | Colorectal Cancer Screening |
| Cureport | Worcester, MA | Nanomedicines |
| , | Acquired by Instem, Jul 2025 | |
| Mayne Pharma | Salisbury South, Australia | Specialty, Generics |
| Adienne Pharma and Biotech | Caponago, Italy | Biologics, Biosimilars |
| ProClinical Consulting | London, UK | Quality, Regulatory and Compliance Consulting |
| Valera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| Zambon | Bresso, Italy | Small Molecules |
| Genentech | Oceanside, CA | Small Molecules, Biologics |
| Perseus Holdings | , | Apparently renamed Elios Therapeutics |
| Aizon | Barcelona, Spain | AI for Pharma Manufacturing |
| Quad Technologies | , | Acquired by Bio-techne, Jun 2018 |
| Harmac Medical Products | Tijuana, Mexico | Contract manufacturer of single-use medical devices |
| RION | Rochester, MN | Exosome Therapeutics |
| PrimeVigilance | Surrey, UK | Safety & Pharmacovigilance |
| HCM Medical | Nijmegen, Netherlands | Contract manufacturer that develops products and implements technologies for the purpose of the production of unique and high-tech medical products |
| Radiant Neurosciences | , | No website Apr 2014-April2015 |
| Modern Biosciences | , | Renamed Istisso |
| MatTek | Ashland, MA | Cell Products, Services |
| Fosun Pharma | Houston, TX | Small molecules, diagnostics, traditional |
| Shilpa Biologicals | Dharwad, India | Biosimilars |
| Kyverna Therapeutics | Emeryville, CA | Treg Cell Therapy for Autoimmune Diseases |
| Microislet | , | Bankrupt 2008 |
| , | Part of Genesis Biotechnology Group | |
| Egenix | , | Assets acquired by Bantam Pharmaceutical, Aug 2015 |
| ClinArt MENA | , | Acquired by CTI Facts, Sep 2020 |
| KaloBios | , | Changed name to Humanigen, Jul7 2017 |
| Response Biomedical | Vancouver, BC | Diagnostic Device |
| Respicardia | , | Acquired by Zoll, Apr 2021 |
| Alstem | Richmond, CA | IPS Generation, Cell Lines, Cytokines, Proteins, etc. |
| EpiDestiny | , | Main program rights acquired by Novo Nordisk, Apr 2018 |
| , | Website taken over Feb 2026 | |
| Lonza | Morristown, NJ | Contract Manufacturing, Reagents, Stem Cells, Services |
| Cirina | , | Merged with Grail, May 2017 |
| Integrated BioTherapeutics | , | Rebranded as AbVacc |
| Cambrex | Agawam, MA | Small Molecules Research, Development & Manufacturing Services |
| Evox Therapeutics | Oxford, UK | Vesicle Therapeutics |
| Lombard Medical | Didcot, UK | Medical Devices |
| Hennig Arzneimittel &Kg | Flörsheim am Main, Germany | Generics, OTC, Contract Manufacturing |
| BioMap | Palo Alto, CA | AI Models |
| Gecko Biomedical | , | Renamed Tissium, May 2019 |
| Worldwide Clinical Trials | Warsaw, Poland | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Website down Oct 2025 - Feb 2026 | |
| Fapon Biopharma | Dongguan, China | Biologics, Immunotherapy |
| Augmenix | , | Acquired by Boston Scientific, Oct 2018, $500M + $100M milestones |
| Narus Development Solutions | , | Gone |
| Acerta Pharma | Oss, Netherlands | Small Molecules |
| Zonare | , | Bought by Mindray, Jul 2013, $64M |
| Revolutionary Medical Devices | , | Acquired by Vyaire, Oct 2017 |
| Aventior | Cambridge, MA | Digital, cloud solutions for life sciences |
| Probiodrug | , | Renamed Vivoryon Therapeutics, Jun 2019 |
| Eppendorf | Oldenburg in Holstein, Germany | Wide Range of Scientific Products |
| Roush Life Sciences | , | Assets purchased by Foxx Life Sciences, 2011 |
| Research Across America | , | Acquired by Synexus, Mar 2016 |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| , | Renamed Torpedo Therapeutics | |
| Eli Lilly | Carolina, PR | Recombinant Insulin |
| Kelai Pharmaceuticals | , | Website down Jun 2023 - Nov 2023; not much info Aug 2022 |
| Captis Biotechnology | , | Website down Dec 2023 - Feb 2024; academic startup by a professor |
| Caladan Therapeutics | Brooklyn, NY | Bioreactor System |
| US Labs | , | Bought by Labcorp |
| RetroSense Therapeutics | , | Bought by Allergan, Sep 2016, $60M |
| VelosBio | , | Acquired by Merck, Oct 2020, $2.75B |
| |
Uster, Switzerland | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Thrive Earlier Detection | , | Acquired by Exact Sciences, Oct 2020, $2.15B |
| Azenta Life Sciences | Manchester, UK | Automation Products |
| Sofregen Medical | Framingham, MA | Silk-based for tissue defects |
| Texcell | Frederick, MD | Contract Research |
| Edico Genome | , | Acquired by Illumina, May 2018 |
| Schrodinger | Framingham, MA | Computation Drug Discovery Platform |
| Wockhardt | Maharashtra, India | Generics, Contract Manufacturing |
| Plato BioPharma | , | Acquired by Inotiv, Oct 2021, $15M |
| Ketogen Pharma | , | No website Feb 2021 - May 2023; Canada based |
| Medrio | San Francisco, CA | Clinical Trial Software |
| Renascions | , | Left Incubator, Dec 2015, Gone |
| Elekta | Stockholm, Sweden | Radiation Therapy & Technology |
| TG Therapeutics | Morrisville, NC | Biologics |
| Riverain Technologies | Miamisburg, OH | Imaging |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| NeoPharm | , | Merged with Insys Therapeutics |
| Lexicon Pharmaceuticals | Bridgewater, NJ | Small Molecules, Biologics |
| CircuLite | , | Bought by HeartWare, Dec 2013, $30M+$320Milestones |
| BioT Medical | Petach Tikva, Israel | Medical Device Connected Care Software |
| Cellipse | , | Website taken over May 2020 |
| myNEO Therapeutics | Ghent, Belgium | Optimized neoantigens for vaccine and cell therapy companies. |
| Oxxon Therapeutics | , | Acquired by Oxford Biomedica Mar 2007 |
| Caidya | Raleigh, NC | Clinical Research Organization |
| Beckman-Coulter | Miami, FL | Medical Electronics |
| Selventa | , | Closed 2016 |
| Advanced Biotherapy | , | Acquired for cash assets by energy company, Mar 2009 |
| Synthetic Biologics | , | Renamed Theriva Biologics, Oct 2022 |
| ECM Biosurgery | , | Website gone Sep 2022 |
| Adapt Produtos Oftalmológicosa | Sao Paulo, Brazil | Surgical Devices |
| OmeCare | , | Website down Mar 2022 - Sep 2022 |
| Centricity Research | Toronto, ON | Clinical Research |
| Avema Pharma | , | Bought by PL Developments |
| |
Durham, NC | Coriolis Pharma – Analytical & development services for biologics. Formulation development, particle analysis, lyophilization & more from preclinical to commercial |
| Cytimmune | , | Website down Feb 2025 - Jul 2025 |
| Triplebar | Emeryville, CA | Antibody Discovery Platform |
| Theravasc | , | As of Feb 2018, Website still lists CEO who left in 2014 |
| Idaho Technology | , | Renamed BioFire Diagnostics |
| Neovii Pharmaceuticals | , | Now Neovii Biotech |
| Exegenesis Bio | Hangzhou, China | Gene Therapy |
| Pharmasset | , | Bought by Gilead, Nov 2011, $11B |
| InnovaVector | Pozzuoli, Italy | AAV CDMO |
| Niramai | London, UK | AI-breast cancer detection device |
| Aspen Pharmacare | Sioux City, IA | Small Molecules |
| Reprise Biomedical | Plymouth, MN | Biological medical devices manufactured using a proprietary perfusion decellularization technology that supports cellular integration. |
| Achelois BioPharma | Redwood City, CA | Molecular Velcro Antiviral Technology |
| Bold Diagnostics | , | Founder gone Apr 2021 |
| Artemis Therapeutics | , | Website down Mar 2024 - Jul 2024; fka New York Global Innovations |
| , | Acquired by Novakand Pharma, Feb 2026, $6M | |
| Lanx inc | , | Acquired by Biomet, Nov 2013, $150M |
| Antibody Research | St. Peters, MO | Antibodies, Hybridomas, Research products |
| Pierre Fabre | Vigoulet-Auzil, France | Oncology, derm / cosmetics |
| , | Shut down Oct 2024 | |
| Javara | Wilmington, NC | Embedded Clinical Research |
| Visum Therapeutics | , | Website gone, CEO Gone, Presumed gone |
| Gilead | Foster City, CA | Small Molecules |
| Vanrx Pharmasystems | , | Acquired by Cytiva, Feb 2021 |
| Firefly Bio | South SF, CA | Degrader-antibody conjugates |
| Chamishi Therapeutics | , | Working under Q-State Biosciences |
| Atropos Therapeutics | San Carlos, CA | Small Molecules Targeting Senescence |
| The Reg Consultants | , | Website down May 2023 - Dec 2023 |
| Frenova | Waltham, MA | Renal clinical research |
| SK Life Sciences | , | Rebranded as parent company's name - SK Biotek |
| Arterex | Bengaluru, India | Medical Device Manufacturing |
| Kinos Medical | , | Merged with restor3d, May 2021 |
| Alphalyse | Palo Alto, CA | Protein Characterization Services |
| Sanofi | Morristown, NJ | Biologics, Vaccines |
| ICI Americas | , | Changed name to Zeneca, 1992 |
| DiaSys Diagnostic Systems | Holzheim, Germany | Diagnostic reagents |
| Picoseq | , | Renamed Depixus |
| Osmotica Pharmaceutical | , | Changed name to RVL Pharmaceuticals, pivoted to aesthetics |
| Dermira | , | Bought by Eli Lilly, Feb 2020, $1.1B |
| EuroAPI | Paris, France | API Production, CDMO |
| Verastem | , | Changed name to Verastem Oncology, May 2018 |
| Qardio | Covina, CA | Portable Heart Monitors |
| More Diagnostics | Los Osos, CA | Diagnostic Controls |
| Poly-Dtech | Strasbourg, France | Nanoparticles, Kits, Antibodies, Services |
| Parker BioConsulting | , | Sole employee is a professional board member |
| Denceptor Therapeutics | , | Website gone Mar 2018 |
| Lusis Biosciences | Hayward, CA | Benchtop Diagnostics |
| Alitair Pharmaceuticals | , | Not registered in MA Feb 2024; No news Oct 2020 - Feb 2024 |
| SeD BioMedical | , | Presumed gone, Some assets acquired by Amarantus, Feb 2017 |
| Purdue Pharma | Wilson, NC | Small Molecules |
| REV Clinical | Ahmedabad, India | Clinical Trials |
| ICON plc. | Farmingdale, NY | Clinical Research |
| Fasteris | Plan-les-Ouates, Switzerland | NGS, Sanger Services |
| BioXpert | , | Website gone Mar 2017, employees gone |
| Breathe Technologies | , | Acquired by Hillrom, Aug 2019, $130M |
| Pervasis | , | Bought by Shire, Sep 2009 |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Mutabilis | , | Website down Aug 2024 - Feb 2025 |
| NextCure | Beltsville, MD | Immune Therapies |
| Gencove | New York, NY | Genome Sequencing |
| Millipede Medical | , | Bought by Boston Scientific, Feb 2019, $325M |
| Becton Dickinson | San Jose, CA | Various medical devices and health products |
| Abbott | Alameda, CA | Diabetes Care |
| Prana Thoracic | , | Prana Surgical, Jan 2025 |
| Kinetic Discovery | , | Acquired by Exscientia, Nov 2018 |
| BostonGene | Waltham, MA | Biomedical Software |
| LumaCyte | Charlottesville, VA | Laser Force Cytology |
| Pharmaust | , | Renamed Neurizon Therapeutics, Oct 2024 |
| AutekBio | , | Website down Oct 2019 - Dec 2019 |
| Delpharm | Lille, France | Contract Manufacturing |
| Lemonex | Seoul, Korea | Drug Delivery, Biosensors |
| Real Research | Krakow, Poland | 3D Cell Culture |
| Gentris | , | Bought by Cancer Genetics Jun 2014 ($6.5M) |
| Sygnis | , | Changed name to Expedeon after acquiring them |
| IDRx | , | Acquired by GSK, Feb 2025 |
| Cooperative Diagnostics | , | Now known as Co-Diagnostics |
| Accelr8 | , | Changed name to Accelerate Diagnostics |
| Loop Genomics | , | Acquired by Element Biosciences, Feb 2022 |
| Anagenesis Biotechnologies | , | Website down Feb 2023 - Jul 2023 |
| Lupin | Goa, India | Generics |
| Boston Biokeys | , | Gone June 2017 |
| Accurant Biotech | Ningbo, China | CMC, Bioanalysis, Consulting |
| Lyric Pharmaceuticals | , | Gone Jul 2019 |
| , | Acquired by IQVIA | |
| Grace Therapeutics (2) | Princeton, NJ | Small Molecule, Medical Food |
| Aptatek BioSciences | Princeton, NJ | Small Molecule Biomarker Sensor |
| Factor Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| ev3 | , | Acquired by Covidien, Jul 2010, $2.6B |
| CorneaGen | Seattle, WA | Ocular surgical solutions |
| Fore Biotherapeutics | Rehovot, Israel | BRAF-Inhibitors, In-licensing others |
| ArgusEye | Linköping, Sweden | Biosensors |
| Qurasense | , | Renamed Qvin |
| Calliditas Therapeutics | Stockholm, Sweden | Small Molecule |
| Oblenio Bio | Oakland, CA | T-cell engager antibody |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Veristat | Chennai, India | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| , | Website down Jan 2026 - May 2026 | |
| Sirius Medical | Eindhoven, Netherlands | Surgical Navigation Software for Tumor Location |
| Apyx Medical | Clearwater, FL | Plastic Surgery & Cosmetic Devices |
| MOLLI Surgical | , | Acquired by Stryker, Jan 2025 |
| Novan Therapeutics | , | Bankrupt, Selling Assets Jul 2023 |
| Bright Pharmaceutical Services | Sherman Oaks, CA | Regulatory Consulting |
| UBC | Creve Couer, MO | Biopharmaceutical Consulting & Services |
| HNP Mirosysteme | Schwerin, Germany | Pumps |
| Katexco Pharmaceuticals | , | Merged into CannBioRx, Jul 2019 |
| ARBORMED | Seoul, Korea | Generics, Small Molecules |
| Differentia Biotech | South SF, CA | Modeling & simulation Technology |
| Brain Biotech | Zwingenberg, Germany | Enzymes, proteins, microbial production strains |
| Sidereal Therapeutics | , | Seems inactive, Apr 2024 |
| Inspira Technologies | Ra'anana, Israel | Respiratory Devices, Blood Monitor |
| MiNA Therapeutics | London, UK | Small activating RNA |
| Worg Biotherapeutics | Shanghai, China | Antigen-Specific Immunotherapies |
| Joint Purification Systems | , | Renamed Osteal Therapeutics |
| Lipoid | Ludwigshafen, Germany | Phospholipids, Acids |
| Calzyme | , | Exceptionally outdated website Jun 2019 |
| Ciel Medical | , | Acquired by Vyaire Medical, Apr 2017 |
| Cytel | Pune, India | Clinical software, statistical services |
| Metaphore Biotechnologies | Boston, MA | Therapeutics based on biomimicry |
| Vibalogics | , | Acquired by Recipharm, Feb 2022 |
| Minimus Spine | , | Only real employee now full-time at another company |
| Pharm-Sintez | Moscow, Russia | Small molecule |
| Recopharma | , | Seems gone |
| CytoCares | Shanghai, China | Immuno-Oncology Antibodies |
| CellBios Healthcare & Lifesciences | McKinney, TX | Blood Products, Bioprocess Equipment |
| RF Surgical Systems | , | Bought by Medtronic, Jul 2015, $235M |
| Two Labs | Powell, OH | Pharmaceutical Consulting |
| Meso Scale Discovery | Rockville, MD | Biologic Assays & Instruments |
| Halyard Health | , | Renamed Avanos Medical, Jun 2018 |
| Lavipharm | Peania, Greece | Small molecules |
| Leco Instrumente | St Joseph, MI | Analytical Equipment |
| Andalay Technologies | , | Company has no money and no employees, Feb 2025 |
| Attagene | , | No news Oct 2020 - Feb 2025 |
| IBA Lifesciences | Goettingen, Germany | Cell Separation, Protein Production, Oligos |
| Lipomics Technologies | , | Acquired by Metabolon, Aug 2012 |
| Adaptate Biotherapeutics | , | Acquired by Takeda, Jan 2022; Spun out of Gammadelta Therapeutics, Oct 2019 |
| ExcepGen | San Francisco, CA | RNA Therapeutics Platform |
| KatahdinRx | , | No website Aug 2019 - Aug 2021; single person outfit in Maine |
| Catalina Pharma | , | No info 2017-2022 |
| Alpha-9 Theranostics | , | Renamed Alpha-9 Oncology, Jan 2024 |
| Strike Pharma | Uppsala, Sweden | Delivery Technology for Immunogenic Peptides |
| Metanotitia | Harbin, China | Metabolomic Data Platform |
| JAMP Pharma | Boucherville, QC | Generics |
| Acambis | , | Bought by Sanofi Pasteur, $276M, Sep 2008 |
| Group K Diagnostics | , | Renamed HueDx, Jan 2023 |
| Idience | Seoul, Korea | Cancer Therapies |
| Raptor Pharmaceuticals | , | Acquired by Horizon Pharma, Oct 2016, $800M |
| Pharmaron | Louisville, KY | R&D Services |
| Arc Bio | , | Merged with Dovetail Genomics to become Cantata Bio |
| D2G Oncology | , | Website down Oct 2024 - Apr 2025; Website has nothing, Jul 2024 |
| Shield Therapeutics | Wellesley, MA | Small Molecules |
| Biolog | Hayward, CA | Cell Phenotyping Technology |
| Medunik | Princeton, NJ | Rare Disease Treatments |
| GEROPHARM | Moscow , Russia | Large drug maker |
| Immtech Pharmaceuticals | , | Website from 2008 as of Mar 2019 |
| Light Chain Bioscience | Geneva, Switzerland | Monoclonal Antibodies |
| Sequana Medical | Zurich, Switzerland | Implantable pump systems |
| Boehringer Mannheim | , | Bought by Roche, May 1997, $11B |
| Advanced Life Sciences | , | Dissolved, May 2012 |
| ProFoldin | , | Website down Dec 2023; Not registered in MA, Feb 2023 |
| Precision Virologics | , | Precision Virologics |
| Cytiva | Amersham, UK | Medical Devices |
| Fenix Biotech | Reading, PA | Life Science Consulting |
| 410 Medical | Durham, NC | Emergency Infusion Device |
| United Therapeutics | Durham, NC | Small Molecules, Biologics |
| Hemadvance | , | Gone |
| OmniAb | Emeryville, CA | Antibody repertoires and high-throughput screening technologies |
| Novaseek Research | , | Website down Jan 2025 - Jun 2025 |
| MAIA Biotechnology | Chicago, IL | Peptide Cancer Therapies |
| Integra LifeSciences | Clayton, Australia | Medical Devices |
| BioDirection | , | Renamed NanoDx, Apr 2020 |
| LemnaGene | , | Acquired by Biolex 2005 |
| XtalPi | Cambridge, MA | AI Drug Design |
| J-Star | South Plainfield, NJ | Contract Chemistry |
| Suzhou Teligene | Suzhou, China | Small Molecules |
| Vestech | Sydney, Australia | Medical device development & commercialization |
| Ori Biotech | London, UK | Cell & Gene Therapy Manufacturing |
| Algenics | , | Website gone Dec 2015 |
| Voyager Biomedical | , | Marked as closed on Google, Dec 2019 |
| ProMetic Life Sciences | , | Renamed Liminal Biosciences, Oct 2019 |
| Avizorex Pharma | , | Acquired by Aerie Pharmaceuticals, Nov 2019; aka AVX Pharma |
| Amgen | Thousand Oaks, CA | Small Molecules, Biologics |
| Ceribell | Sunnyvale, CA | Fast EEG |
| Michrom | , | Bought by Bruker, Feb 2011 |
| TriMetis Life Sciences | Germantown, TN | Biospecimens |
| MGC Diagnostics | St. Paul, MN | Diagnostic Machines |
| Gerostate Alpha | , | Shut down Dec 2024 |
| BioArra | , | Bought by VWR Nov 2016 |
| InnovaTID Pharmaceuticals | , | Closed Nov 2018; fka InnovaTID |
| Cryterion Medical | , | Boston Scientific acquired remaining 65% stake, Jul 2018, $202M |
| Meribel Pharma Group | Karlskoga, Sweden | Contract Manufacturing |
| Raydiant Oximetry | San Ramon, CA | Fetal Monitor |
| Gensia Sicor | , | Renamed Sicor |
| IMMUSE Therapeutics | Seoul, Korea | Cancer Immunotherapy |
| Healx | Cambridge, UK | AI Drug Discovery |
| Navitas Life Sciences | Pallikaranai, India | Decentralized Clinical Research, Consulting |
| Innovative Supply Solutions | Southampton, PA | Clinical Trial Software |
| Affinity Therapeutics | , | Website down Oct 2021 - Feb 2022 |
| Splice Histology | Worcester, MA | Histopathology Services |
| Aneuvo | Los Angeles, CA | Neuromodulation Devices |
| NEXGEL | Langhorne, PA | Hydrogels |
| ZefSci | San Diego, CA | Chromatography Equipment & Services |
| Segmed | Palo Alto, CA | Cloud based platform for AI development |
| Inspire Pharmaceuticals | , | Acquired by Merck 2011 |
| ElexoPharm | , | Website gone Oct 2019; Assets seem to have moved to Angion |
| Ceremedix | , | Changed name to Ischemix, 2006 |
| InSymbiosis | , | Acquired by Camargo, Jun 2019 |
| Nutromics | Brunswick, Australia | Wearable Diagnostic Device |
| Enzo Biochem | , | |
| Randox Laboratories | Kearneysville, WV | Clinical Diagnostics |
| NeuroProof | Rostock, Germany | Neuroscience CRO |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cell Point | , | Renamed Cell Theranostics, Jan 2022 |
| Iris Biotech | Marktredwitz, Germany | Peptides, Reagents, Resins |
| Libra Therapeutics | San Diego, CA | Small Molecules for Neurodegenerative Indications |
| Vedere Bio II | , | Shut down Mar 2023 |
| Fresenius Kabi | Nanchang, China | Contract Manufacturing |
| Convelo Therapeutics | Cleveland, OH | Stem Cell Stimulating Therapy |
| PhAST Diagnostics | Boston, MA | AI Imaging Technology |
| AccessClosure | , | Bought by Cardinal Health, May 2014 |
| Resilience | East Norriton, PA | Biomanufacturing |
| America Stem Cell | , | Changed name to Targazyme |
| Vallon Pharmaceuticals | , | Acquired by GRI Bio, Apr 2023 |
| Euroscreen | , | Renamed Ogeda Oct 2016 |
| Kuur Therapeutics | , | Acquired by Athenex, May 2021, $70M stock + $115M milestones; fka Cell Medica |
| MicroDose Therapeutx | , | Bought by Teva, Jun 2013, $40M + $125 milestones |
| Percival Scientific | Perry, IA | Incubators, reach-in and walk-in custom stability chambers |
| BioLegacy Research | San Diego, CA | Contract Research |
| CathWorks | Kfar-saba, Israel | Catheter Guidance |
| Arterex | Pleasanton, CA | Medical Device Manufacturing |
| Schrodinger | Cambridge, MA | Computation Drug Discovery Platform |
| Colorado Therapeutics | Louisville, CO | Crosslinked Soft Tissue Repair Material |
| AGI Dermatics | , | Acquired by Estee Lauder, Sep 2008 |
| Winteam Pharmaceutical | , | Website taken over, Sep 2017 |
| Reveal Biosciences | , | Acquired by CellCarta, May 2021 |
| EpiCapture | , | Acquired by Trinity Biotech, Oct 2024, $3M |
| Pharmaceutical Development Group | Tampa, FL | Regulatory Consulting |
| Life & Brain | Bonn, Germany | R&D for cellomics, genomics, and neurocognition |
| SP Lab Services | , | Website down Sep 2021 - Jan 2022 |
| Quartet Medicine | , | Wound down, Nov 2017 |
| , | Liquidated 2024 | |
| Corbin Therapeutics | , | Website down Oct 2021 - Jul 2022 |
| CorrectSequence Therapeutics | Shanghai, China | Base Editing Therapies |
| Apaxen | , | Website down Feb 2025 - Jul 2025 |
| Prime Genomics | , | Renamed AeenaDx, May 2022 |
| Aros Applied Biotechnology | , | Acquired by eurofins |
| CaroCure Discovery Solutions | , | Website down Feb 2022 - Jul 2022 |
| AMEGA Biotech | Buenos Aires, Argentina | Contract Biosimilars |
| Chronos Therapeutics | , | Acquired by Evgen, Mar 2024 |
| Cambrex | East Rutherford, NJ | Small Molecules Research, Development & Manufacturing Services |
| Sironax | Beijing, China | Therapies that address the root cause of age-related degenerative disease |
| Provell Pharmaceuticals | , | Bankrupt Apr 2025 |
| Applied Biology | , | All assets purchased by Jupiter Wellness, Jun 2022 |
| Syntimmune | , | Acquired by Alexion, Nov 2018, $400M + $800M milestones |
| Novo Nordisk | Bagsvaerd, Denmark | Diabetes Care |
| Neurolink Medical | , | Website down Feb 2022 - Jul 2022 |
| Mithridion | , | Website Gone, Company appears to be as well |
| Neuronex | , | Acquired by Acorda Therapeutics, Dec 2012, $6.8M |
| BioPharma Global | , | Acquired by Pace Life Sciences, Sep 2022 |
| Mitologics | Romainville, France | CRO mitochondrial effects of chemicals or biology |
| Quantoom Biosciences | Nivelles, Belgium | RNA Production |
| Genovis | Kävlinge, Sweden | Nanoparticles |
| Lodo Therapeutics | , | Acquired by Zymergen, May 2021 |
| DiaCarta | Tianjin, China | Molecular Diagnostics Tests |
| Biomirex | , | Business Registration Revoked, Jul 2019 |
| Rhaeos | Evanston, IL | Shunt Monitor |
| Clinical Trials Research Services | , | Clinical Trials Research Services |
| Crown Bioscience | San Diego, CA | Drug Development |
| Kannalife | , | Renamed Neuropathix, May 2021 |
| ATXCo | , | Acquired by Blade Therapeutics, Sep 2019 |
| Galvani Bioelectronics | South SF, CA | Miniaturized, implantable devices |
| ICON plc. | Blue Bell, PA | Clinical Trials, Consulting |
| Bioharmony Therapeutics | , | Website down Apr 2024 - Sep 2024 |
| Pangea Biomed | Tel Aviv, Israel | AI-Enabled Precision Drug Development |
| Supeira | , | Website gone Mar 2023 |
| Regenicin | , | Residential address, three employees, no money |
| Tarsa Therapeutics | , | Product rights acquired |
| Zata Pharmaceuticals | Worcester, MA | RNA, DNA Therapeutics |
| ADC Biotechnology | , | Acquired by Sterling Pharma Solutions, Apr 2021; aka ADCBIO |
| VaxInnate | , | Dissolved Feb 2017 |
| Enceladus Pharmaceuticals | , | Website gone Sep 2020 |
| Twist Bioscience | Singapore, Singapore | Synthetic DNA, genes and libraries |
| ApiJect | Stamford, CT | Single-use injectable delivery system |
| Lumen Therapeutics | , | No updates on website since 2006 as of Feb 2021 |
| Moberg Pharma | Stockholm, Sweden | Small Molecules |
| VesiCURE Therapeutics | Suzhou, China | Exosome Delivery |
| Tailored Therapeutics | , | Website down Jan 2024 - Aug 2024 |
| ClinPharm Consulting | , | Renamed Kinetigen, Jan 2013 |
| Ovizio Imaging Systems | , | Acquired by Chemometec, Oct 2024 |
| PolyPeptide Group | Limhamn, Sweden | Polypeptide Manufacturing |
| |
Cranbury, NJ | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| , | Website down Nov 2025 - Dec 2025 | |
| Riverside Clinical Research | , | Renamed Velocity Clinical Research |
| Clinilabs | Eatontown, NJ | Clinical Research |
| Recensa Therapeutics | , | Only employee gone 2018 |
| AnX Robotica | Plano, TX | Medical Device Capsules |
| Resonetics | Hutchinson, MN | Contract Medical Device Manufacturing & Development |
| NiKang Therapeutics | Wilmington, DE | Small Molecules for Oncology |
| Avergen | , | Website down Jul 2021 - Nov 2021 |
| Five Alarm Bio | Cambridge, UK | Aging Therapies |
| Regeneus | , | Merged with Cambium, Apr 2024 |
| Nexcida Therapeutics | , | Business Surrendered in CA, Aug 2016 |
| Invex Therapeutics | Perth, Australia | Repurposed Drug |
| Synthetic Gestalt | Tokyo, Japan | AI Drug Discovery |
| Conversant Bio | , | Merged with Folio Biosciences, Renamed Folio Conversant, Merged into Discovery Life Sciences Oct 2018 |
| Decibel Therapeutics | , | Acquired by Regeneron, Sep 2023, $109M + $104M milestones |
| Glooko | Palo Alto, CA | Glucose monitoring App |
| Omniome | , | Acquired by Pacific Biosciences, Sep 2021, $800M |
| Helsinn | Iselin, NJ | Small Molecules |
| Cell Matrix | , | Acquired by Cancervax |
| De Novo Software | Pasadena, CA | Flow Cytometry and Image Cytometry Data Analysis Software |
| Allergy Therapeutics | West Sussex, UK | Allergy Vaccines |
| Tyrogenex | , | Xcovery offshoot. Co-located, same employees |
| Cellgate | , | Acquired by ProGen, Feb 2008, $2.5M |
| NeuroStorm Studios | , | Website down Oct 2021 - Jul 2022 |
| Cellona | , | Founder left, Site taken over Aug 2017 |
| Centessa Pharmaceuticals | Boston, MA | Umbrella company acquiring drug companies |
| Abbott | Mississauga, ON | Diagnostics |
| InDevR | Boulder, CO | Life Science Instrumentation & Assays |
| Nimbus Therapeutics | Boston, MA | Computer-Based Drug Discovery |
| Pronova BioPharma | , | Acquired by BASF, Jan 2013 |
| CordenPharma | Liestal, Switzerland | API Manufacturing |
| NeuroVive Pharmaceutical | , | Renamed Abliva, May 2020 |
| Melior Discovery | Exton, PA | High Throughput Screening for New Indications |
| Prosidion | , | Bought by OSI pharmaceuticals, Apr 2005 |
| MercaChem | , | Renamed Symeres, Nov 2020 |
| Princeton BioMeditech | Monmouth Junction, NJ | POC Diagnostics |
| , | Website down Jan 2026 - May 2026 | |
| Lisa Cryobanking | , | Shut down Jun 2021 |
| ONI | Oxford, UK | Super-Resolution Microscopy |
| Ixchelsis | , | Website taken over by a church, Jan 2024 |
| LifeSync | Coral Springs, FL | Cardiac Monitoring |
| Profil Institute for Clinical Research | , | Renamed ProSciento |
| Allena Pharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| GVK Biosciences | , | Renamed Aragen Life Sciences |
| GTC Biotherapeutics | , | Now rEVO Biologics 2013 |
| West Pharma | Le Nouvion-en-Thiérache, France | Pharmaceutical Supplier |
| Polgenix | , | Don’t believe this company is active; website from 2006 as of Dec 2019 |
| Vivitide | , | Combined with Biosynth Carbosynth and Pepscan to become Biosynth, Sep 2022 |
| PPD | Wilmington, NC | Contract R & D, Consulting |
| , | Website down Jan 2026 - May 2026 | |
| Genetron Health | Beijing, China | Diagnostics |
| Saluda Medical | Terheijden, Netherlands | Spinal Cord Stimulation Device |
| Sapience Therapeutics | Tarrytown, NY | Peptide-based Therapies for cancers |
| Cerapedics | Westminster, CO | Biologic Bone Grafts |
| Blue Therapeutics | , | Website down Feb 2023 - Jul 2023 |
| ITR Laboratories | Montréal, QC | Toxicology Services |
| Thyritope Biosciences | , | Closed Oct 2016 |
| Antara Biosciences | , | Bankrupt 2007 |
| Spectro Analytical Instruments | Kleve, Germany | Spectrometers, Analyzers |
| Diagenode | Seraing, Belgium | Lab Assays & Reagents |
| Calidum | , | Doesn't seem serious, Mar 2022 |
| Clover Biopharmaceuticals | Chengdu, China | Biologics |
| Roche | Penzberg, Germany | Diagnostics |
| Accentia Biopharmaceuticals | , | Bankrupt, 2013 |
| CONMED | Utica, NY | Surgical, Medical Devices |
| O-Ray pharma | , | Inactive Jun 2022 |
| Causeway Therapeutics | Glasgow, UK | microRNA |
| Signostics | , | Renamed EchoNous, Jul 2020 |
| Qualiber | , | Presumed inactive, website gone |
| CDR Therapeutics | , | Merged with CellGenEx to form Xcyte, Jan 1998 |
| Catherex | , | Spun out of Medigene, sold to Amgen, Dec 2015, $10.5M |
| Data Sciences International | St. Paul, MN | Animal Monitoring, Services |
| , | Became part of Accelerator, Dec 2025 | |
| Lotus Clinical Research | Pasadena, CA | Clinical Research |
| MicroSkin Ostomy Pouching Systems | , | Renamed Cymed Ostomy |
| CARR Biosystems | Clearwater, FL | Bioseparations |
| BioGaia | Stockholm, Sweden | Probiotics |
| Recombio | , | Seems to have rebranded as Vaxira, which is also a product |
| Medikine | San Diego, CA | Small Molecules, Peptide |
| Abcore | , | Acquired by Fortis Life Sciences, Mar 2022 |
| MP Biomedicals | Solon, OH | Diagnostics & Life Sciences Products |
| , | Website down Sep 2025 - Dec 2025 | |
| Nexus Pharmaceuticals | Lincolnshire, IL | Repurposing off-patent molecules |
| Tranxenogen | , | Assets sold in 2004. Website is copyright 2002. No evidence of termination of business, but not likely they are active |
| Genturi | , | Website down Feb 2021 - Sep 2021 |
| Datacubed Health | King of Prussia, PA | Clinical Software |
| Hualan Bio | , | Website down Feb 2022 - Jul 2022 |
| Kojin Therapeutics | , | Winding down Feb 2025 |
| Verséa Health | Tampa, FL | Diagnostics |
| Allergen Research Corporation | , | Renamed Aimmune Therapeutics, May 2015 |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Hologic | Zaventem, Belgium | Diagnostic, Imaging |
| Keenova | Malvern, PA | Small Molecules |
| Alliance Biosciences | , | Acquired by WIRB-Copernicus Group, Jul 2014 |
| LynxDx | Ann Arbor, MI | Diagnostics |
| Noscira | , | Liquidated |
| Concept Medical | Surat, India | Coated Balloon Catheter, Drug-eluting stent with balloon |
| , | Acquired by Embecta, Mar 2026 | |
| Novotech | Hong Kong, China | Clinical Research |
| Moleac | Singapore, Singapore | Stroke Products |
| Anteco Pharma | , | Acquired by Attwill Vascular, Nov 2017 |
| Harbor Biosciences | , | Changed name to Harbor Therapeutics |
| , | Filings late Jun 2022 - Dec 2025; Website down Sep 2025 - Dec 2025 | |
| EyeBio | , | Acquired by Merck, Jul 2024, $1.3B + $1.7B milestones |
| Fineimmu | Guangzhou, China | T Cell Therapies |
| Evotec | Abingdon, UK | Contract drug discovery & development offering integrated solutions from Target ID through to Clinic |
| Hope Biosciences | Sugar Land, TX | Autologous mesenchymal stem cells, growth media |
| OriMAbs | , | Gone post 2022 |
| Collateral Therapeutics | , | Acquired by Schering, Mar 2002, $140M stock |
| Bioserve | , | Acquired by ReproCell, 2014 |
| Rockwell Medical | Wixom, MI | Dialysis Products |
| EAG Laboratories | Maryland Heights, MO | Analytical & Synthesis Services |
| SynCardia Systems | Tucson, AZ | Artificial Hearts |
| Stellanova Therapeutics | , | Folded into parent, Sep 2023 |
| LEAD Therapeutics | , | Acquired by BioMarin Pharmaceuticals, 2010 |
| Novaptech | Gradignan, France | Custom Aptamers, Rapid Test Kits |
| Sonnest | , | Website down Jan 2025 - May 2025 |
| Evgen Pharma | , | Acquired Chronos Therapeutics and changed name to TheraCryf, Mar 2024 |
| Euclid Diagnostics | , | SBIR 2013. No info Jun 2015. Technically active Jun 2018 |
| Sciformix | , | Acquired by LabCorp, Jun 2018 |
| Nuvelution Pharma | , | Gone 2020 |
| Masy Systems | , | fka Masy Biosystems |
| Igen Biotech | , | Website down Sep 2023 - Mar 2024 |
| Cytometix | , | Seem to have changed their name to Cmxtwenty |
| SimPharma | , | Website down Sep 2022 - Feb 2023 |
| Phalanx Biotech | , | Website down Jun 2023 - Dec 2023 |
| Cenyx Biotech | Seoul, Korea | Nanocompounds |
| UBC | Geneva, Switzerland | Biopharmaceutical Consulting & Services |
| DELFI Diagnostics | Palo Alto, CA | Cancer Diagnostics |
| Lynx Therapeutics | , | Acquired by reverse merger with Solexa, 2005 |
| Avam | Odessa, FL | Clinical Diagnostics |
| bioMerieux | Lombard, IL | Diagnostics |
| Confer Health | , | Shut down 2021 |
| Adela | Toronto, ON | Liquid Biopsy |
| Aterovax | , | French IVD company, founded 2013 - website not active Dec 2018 - Dec 2019 |
| SAI MedPartners | Reading, PA | Biopharmaceutical & Medical Device Consulting |
| Auxilium Pharmaceuticals | , | Acquired by Endo Oct 2014, $2.6B |
| MyBiotics | Rehovot, Israel | Bacterial Products |
| Jaggi Ophthalmic | Gurgaon, India | Ophthalmic Equipment |
| Pragma Therapeutics | , | Website down Jul 2022 - Nov 2022 |
| iVascularU | Sant Vicenç dels Horts, Spain | Vascular Devices |
| Lumenis | Aichi, Japan | Energy-based medical treatments |
| LGM Pharma | Boca Raton, FL | APIs, CDMO Services |
| Crista Biologics | , | No website Jul 2022 - Jul 2025 |
| Athenagen | , | Merged with Zapaq to become CoMentis, Aug 2006 |
| Gene Labs | , | Bought by GSk 2008 |
| InnoSer | Leiden, Netherlands | Preclinical CRO |
| N-Gene Research Laboratories | , | Website down Jun 2023 - Dec 2023 |
| Nuclein | Austin, TX | Handheld PCR Diagnostics |
| Magenta Therapeutics | , | Acquired by Dianthus, Sep 2023 |
| Alva Health | Dallas, TX | Remote Stroke Monitoring |
| AhR Pharmaceuticals | , | Website gone, twitter gone Aug 2017. One employee on LinkedIn |
| Corscience | Erlangen, Germany | Development and OEM supply of defibrillation, patient monitoring, and critical care systems |
| DIANA Biotechnologies | Vestec, Czech Republic | PCR Products |
| BIOMODEX | , | Acquired by Mentice |
| EnCor Biotechnology | Gainesville, FL | Research Antibodies |
| Ellipse Technologies | , | Bought by NuVasive, Jan 2016, $380M |
| Oncodesign Services | Villebon-sur-Yvette, France | Preclinical services |
| Groupe PARIMA | Montréal, QC | CDMO specialized in the development & manufacturing of liquids, suspensions, & semi-solid products |
| Valpharma | Serravalle, San Marino | Generics, Contract Manufacturing |
| Xeltis | Eindhoven, Netherlands | Tissue Engineering |
| Allucent | Amsterdam, Netherlands | Clinical Research Solutions partnering with small & mid-sized biotechs to deliver novel therapies to patients with unmet needs. |
| , | Now PamDx, May 2026 | |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Cortalix | Groningen, Netherlands | Nanobody Platform for Novel Radiopharmaceuticals |
| SAB Biotherapeutics | , | Renamed SAB BIO |
| Artcline | Rostock, Germany | Functional Sepsis Therapy |
| Matice Biosciences | , | Renamed Animate Biosciences, Mar 2025 |
| Nimbic Systems | , | Acquired by Mizuho OSI, Sep 2020 |
| Xegen | Gemenos, France | NGS Data Analysis |
| Arizona Research Center | Phoenix, AZ | Clinical Research |
| Pierre Fabre | Gien, France | Oncology, derm / cosmetics |
| Amsterdam Molecular Therapeutics | , | Acquired by UniQure |
| ClinBAY | Limassol, Cyprus | Clinical Trial Biometrics |
| Serosep | Limerick, Ireland | Molecular Enteric Testing |
| DePuy Synthes | , | Rolled into Johnson & Johnson MedTech, Sep 2024 |
| Afexa Life Sciences | , | Acquired by Valeant Oct 2011 |
| NanoSyrinx | Coventry, UK | Genetically encoded drug delivery system |
| , | Website down Jan 2026 - May 2026 | |
| Galux | Seoul, Korea | in silico Drug Discovery Platform |
| WNDM Medical | , | Renamed Sanara MedTech, May 2019 |
| VISEN Pharmaceuticals | Shanghai, China | Endocrine Diseases |
| OptraScan | Pune, India | Digital Slide Scanners, Software |
| Neurogene | Houston, TX | Genetic Therapies |
| Ionica Sciences | , | Website down Mar 2023 - Dec 2023 |
| NanoImaging Services | San Diego, CA | Cryo-EM Services |
| Occam Design | Louisville, SS | Medical Device Development |
| Enquyst Technologies | Lowell, MA | Biologics Manufacturing |
| EPISONA | , | Gone Nov 2018 |
| nVision Medical | , | Acquired by Boston Scientific, Apr 2018, $275M |
| Forus Therapeutics | Oakville, ON | Distributor, R&D |
| Orphan Europe | , | Acquired by Recordati, Sep 2007 |
| Thermo Fisher | Burlington, ON | Molecular Biology Supplies |
| , | Website messed up, single employee, Dec 2025 | |
| ndd Medical Technologies | Zurich, Switzerland | Lung Diagnostics Devices |
| TearLab | , | Renamed Trukera Medical, Sep 2022 |
| Nexstim | Helsinki, Finland | Transcranial Magnetic Stimulation |
| Xcellerex | , | Acquired by GE Healthcare, May 2012 |
| Anchen | , | Bought by Par Pharmaceutical |
| Viant Medical | Fort Wayne, IN | Contract Medical Devices |
| Akesobio | Zhongshan, China | Antibody Therapies |
| Hardy Diagnostics | Santa Maria, CA | Plate Reader Device |
| XtalPi | Shenzhen, China | AI Drug Design |
| Spiration | , | Acquired by Olympus, Jun 2010 |
| Paragon Bioservices | , | Acquired by Catalent, May 2019, $1.2B |
| Moberg ICU Solutions | , | Acquired by Natus, Dec 2022 |
| LightIntegra Technology | , | Website taken over Feb 2022 - Apr 2022 |
| Cirqle Biomedical | , | Website down Sep 2022 - Feb 2023 |
| ARCBio | , | Shut down 2014 |
| LAM Therapeutics | , | Renamed AI Therapeutics |
| Bristol Myers Squibb | Devens, MA | Small Molecules, Biologics |
| McGee Pharma | , | Merged with Pharmalex |
| Chromos Molecular Systems | , | Folded into Umbrella company, Sep 2008 |
| Bionique Testing Laboratories | Saranac Lake, NY | Mycoplasma Testing & Diagnostics |
| Fairway Medical Technologies | , | Website gone |
| , | Website down Nov 2025 - Apr 2026; fka HpVac | |
| Synomics | , | Now Smithers Pharma Services |
| PharSafer | Surrey, UK | Pharmacovigilance and Medical Information Services |
| Northwest Clinical Trials of Denver | , | Website down Feb 2020 - Apr 2020, presumed defunct |
| Parimer Scientific | Easley, SC | Contract Pharmaceutical Manufacturing |
| MEDIPIC | , | Website down Mar 2025 - Jul 2025 |
| Centrient Pharmaceuticals | Rotterdam, Netherlands | Generics, APIs |
| MBF Bioscience | Williston, VT | Imaging and visualization solutions |
| BIORON | Römerberg, Germany | manufacturer and global distributor of molecular biology and diagnostic products |
| JangoBio | Fitchburg, WI | Novel regenerative therapies that restore hormone balance |
| Synspira Therapeutics | , | Renamed Anagram Therapeutics, Apr 2023 |
| Tsirona Genetic Systems | , | Website not really done, Nov 2019 - May 2020; not registered business in MA Nov 2019 |
| Advion Interchim Scientific | Ithaca, NY | Immunoassays |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Curiox Biosystems | Woburn, MA | Assay Platform |
| Akina | West Lafayette, IN | 3D substrate, drug-containing microparticle device, formulation services, polymer drug delivery |
| Falcon Therapeutics | , | CEO gone, website down Jun 2021 - Jul 2021 |
| Gameto | New York, NY | Female Fertility Extension |
| Mederi Medical | , | Acquired by Restech, Apr 2018 |
| ACANS Pharmaceuticals | , | 2015 startup, no website Jan 2019 - Aug 2020 |
| Geneos Therapeutics | Philadelphia, PA | Plasmid-based Neoantigen-targeted Cancer Therapies |
| Mitoconix | , | Website gone Sep 2019 - Aug 2021 |
| Nano3D Biosciences | , | Assets sold to Greiner Bio-One, May 2018 |
| Ferring Pharmaceuticals | St. Prex, Switzerland | Small Molecules, Biologics |
| Martek Biosciences | , | Bought by DSM |
| Muse Bio | , | Renamed Inscripta, Nov 2017 |
| Viant Medical | Elkhorn, WI | Contract Medical Devices |
| , | Renamed Edding, Feb 2026 | |
| Lyell Immunopharma | Bothell, WA | Curative cell-based immunotherapies |
| ImStar Therapeutics | , | Website not working May 2021 - Sep 2021 |
| Recros Medica | , | Website down Jul 2022 - Nov 2022 |
| Aktis Oncology | Boston, MA | Targeted radiopharmaceuticals |
| Tenex Health | Lake Forest, CA | Minimally invasive technology for treatment of chronic tendon pain |
| Rocket Pharmaceuticals | Cranbury, NJ | Gene Therapies |
| iBio | San Diego, CA | Antibody Therapies |
| Libra Medical | , | Acquired by RQM+, May 2023 |
| Tempero Pharmaceuticals | , | GSK subsidiary, no longer has own website, may have been absorbed |
| Indevus | , | Acquired by Endo Pharmaceuticals 2009 |
| AiPing Pharmaceutical | , | Part of A&Z Pharmaceutical |
| Aperiomics | , | Website down Dec 2021 - Apr 2022 |
| Transplant Genomics | Lenexa, KS | Monitoring to prevent transplant rejection |
| , | Renamed Racura Oncology, Dec 2025 | |
| Grespo | , | Part-time CEO, seems nonserious Feb 2023 |
| , | Renamed Atisama Therapeutics, May 2026 | |
| Cobra Biologics | , | Bought by Cognate BioServices, Nov 2019 |
| Solid State Pharma | Halifax, NS | Crystallization Services |
| Confluent Medical Technologies | Windham, DE | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Actavis | , | Acquired Allergan, $70B, Took Allergan name |
| Rune Labs | San Francisco, CA | Brain data analysis platform |
| Neurogen | , | Acquired by Ligand Pharmaceuticals 2009 |
| Hydrix | Melbourne, Australia | Cardiovascular Devices, Device Contract Work |
| QNTM Labs | Odense , Denmark | Analytical Testing |
| Theron Pharmaceuticals | , | RD since 2011, no updates since 2011, no employees on LI Jun 2020 |
| Phase Forward | , | Bought by oracle |
| Genalyte | San Diego, CA | Multiplexing Instruments |
| SPAAR Research Labs | Chennai, India | Contract Development Organization |
| Advanced Biomaterial Systems | , | No site, no news since 2006 as of Jan 2019 |
| Regenacy Pharmaceuticals | , | Shut down Sep 2023; Spun out of Acetylon prior to Celgene acquiring them, Dec 2016 |
| AtaiBeckley | Virtual, | Psychedelics for mental Health |
| Affigen | , | Liquidating Fall 2019 |
| Vieworks Imaging Expert | Gyeonggi, Korea | Imaging |
| Selah Genomics | , | Seems gone after being sold back to founder |
| Angitia Biopharmaceuticals | Woodland Hills, CA | Bispecific Antibody |
| AquaBounty Farms | , | Changed named to Aqua Bounty 2004 |
| Confluent Medical Technologies | Scottsdale, AZ | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Tyco Electronics | , | Changed name to TE Connectivity, Mar 2011 |
| MarWell Bio | South SF, CA | Generative AI Antibody Design |
| MerciaPharma | , | No updates 2014-2023 |
| ProtaGene | Heilbronn, Germany | Advanced, integrated, and complete analytical solutions and expert consultation. |
| PONTiS Orthopaedics | , | Website down Dec 2022 - Apr 2023 |
| Singular Bio | , | Acquired by Invitae, Jun 2019 |
| ApiJect | Durham, NC | Single-use injectable delivery system |
| Charles River Laboratories | Leiden, Netherlands | Research Animal Models and Preclinical Research |
| Zebra Biologics | , | Website gone May 2020 - Aug 2020 |
| U3 pharma | , | Bought by Daiichi Sankyo, May 2008, $235M; closed 2015 |
| EryDel | , | Acquired by Quince Therapeutics, Oct 2023 |
| HawkCell | Lyon, France | MRI Research Technology |
| Tiaki Therapeutics | , | Website down Nov 2022 - Apr 2023 |
| CIVCO Radiotherapy | , | Renamed CQ Medical |
| Plaxgen | , | Shut Down 2019 |
| , | Renamed Algernon Health, Oct 2025 | |
| Virscio | New Haven, CT | Contract Research & Consulting |
| Selleckchem | Houston, TX | Chemicals, Antibodies, Etc |
| Armas Pharmaceuticals | Freehold, NJ | Generic Pharmaceuticals |
| Ocuphire Pharma | , | Acquired Opus Genetics, Oct 2024, took name will focus on gene therapy |
| Omni-Tract Surgical | , | Acquired by Integra LifeSciences, Jan 2009 |
| Surv Biopharma | Kagoshima, Japan | Conditionally-replicating adenovirus |
| Xanthus Pharmaceuticals | , | Acquired by Antisoma, Jun 2008 |
| Cortex Pharmaceuticals | , | Renamed RespireRx Pharmaceuticals, Dec 2015 |
| |
Kraków, Poland | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| BioCryst Pharmaceuticals | Birmingham, AL | Small Molecules |
| Treventis | Toronto, ON | Alzheimer's Treatment |
| Negma Labs | , | Bought by Wockhardt, May 2007, $265M |
| Sharp | Heerenveen, Netherlands | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Nextwave Pharmaceuticals | , | Bought by Pfizer Oct 2012; Sold to Tris Pharma Sep 2018 |
| Lupin | Somerset, NJ | Generics |
| Mabcare Therapeutics | , | |
| ALPCO Diagnostics | Salem, NH | Immunoassays, reagents, proteins |
| Karyopharm Therapeutics | Newton, MA | Small Molecules |
| |
León, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Telix Pharmaceuticals | North Melbourne, Australia | Radio immunotherapy |
| Odin Pharmaceuticals | Somerset, NJ | Sterile pharmaceutical company that develops injectable and ophthalmic drugs |
| DiaMentis | Quebec, QC | Mental Health Disorder Diagnosis |
| AlzeCure Pharma | Huddinge, Sweden | Alzheimer's Focused Treatments |
| Atanse | , | Website gone, May 2018 |
| Homology Medicines | , | Merged with Q32 Bio Mar 2024 |
| Metabogenix Technologies | , | Gone Sep 2015 |
| , | Merged with NeuroX to become MindMaze Therapeutics, Dec 2025 | |
| SCG Cell Therapy | Singapore, Singapore | Adoptive cell therapy, bispecific antibodies and vaccines |
| Stemgen | , | Website gone Feb 2020 - Mar 2021 |
| EAG Laboratories | San Diego, CA | Analytical & Synthesis Services |
| Defined Health | , | Renamed Cello Health Bioconsulting |
| Bionovis Brasil | Valinhos, Brazil | Biologics |
| Bioventus | Durham, NC | Orthobiologics |
| Olaris Therapeutics | Framingham, MA | Diagnostics |
| RevDia | , | Founded in 2001, but rebranded and was masquerading as a startup. Assets bought by board members who are trying to relaunch as of Sep 2014 |
| NexMed | , | Now Apricus Bio |
| OLS Omni Life Science | Bremen, Germany | Cell Research Products |
| Bolder Biotechnology | Boulder, CO | Biologics |
| WntRx Pharmaceuticals | , | No updates/info 2013-2022 |
| Chai | , | Website down Apr 2025 - Aug 2025 |
| |
Rozzano, Italy | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Shield Therapeutics | Gateshead Quays, UK | Small Molecules |
| TFS | Lund, Sweden | Clinical Research |
| Astellas | Tokyo, Japan | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Medochemie | Limassol, Cyprus | Generics |
| Analytics 4 Life | , | Renamed CorVista Health, Dec 2020 |
| BioOra | Wellington, New Zealand | Next-generation CAR-T therapies |
| Avalign Technologies | Tuttlingen, Germany | Orthopedics & Surgical |
| Talisman Therapeutics | Cambridge, UK | Alzheimer's Stem Cell Model |
| Sequoia Sciences | , | Folded in to Sequoia Vaccines |
| Ever Neuro Pharma | Unterach, Austria | Generics, Specialty |
| Somerset Therapeutics | Bengaluru, India | Injectable, Ophthalmic CDMO |
| Heraeus Medical | Hong Kong, China | Medical Devices |
| Attenuon | , | Now Tactic |
| Artemis Diagnostics | , | Changed name to Lightpoint Medical, Jan 2013 |
| Zebra Medical Vision | , | Merged with Nanox, Nov 2021 |
| Gadea Pharmaceutical | , | Acquired by AMRI, 2015, $174M |
| Epigen Biosciences | San Diego, CA | Drug Discovery & Development |
| Moderna Therapeutics | Norwood, MA | RNA Therapies |
| VisionQuest Biomedical | , | Seems gone Apr 2025 |
| Biocartis | Mechelen, Belgium | Molecular Diagnostics |
| Arstasis | , | Appears Gone Sep 2017 |
| Biorez | , | Acquired by CONMED, Aug 2022; fka Soft Tissue Regeneration |
| H.E.L. Group | Beijing, China | Parallel and high pressure biotechnology lab equipment |
| MacroGenics | Rockville, MD | Bispecific Antibodies |
| ClearView | Newton, MA | Strategic Consulting |
| Tapemark | , | Acquired by LTS, Aug 2022 |
| , | No news 2020 - Oct 2025; Business Lapsed, Aug 2025 | |
| Eppendorf | Hong Kong, China | Wide Range of Scientific Products |
| Teleflex Medical | Wayne, PA | Surgical and Medical Devices |
| Alfasigma | Bologna, Italy | Small Molecules? |
| NeoCura | Shenzhen, China | Personalized Vaccines |
| Apozeal Pharmaceuticals | Levittown, PA | Generics |
| Alfa Cytology | Hauppauge, NY | Cancer therapeutic development and preclinical studies |
| Neogene Therapeutics | , | Acquired by AstraZeneca, Jan 2023, $200M + $120M milestones |
| Novavax | Gaithersburg, MD | Virus-like Particles, Micelles |
| Recipharm | Kayserberg, France | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Chromocyte | , | |
| Immatics Biotechnologies | Tübingen, Germany | Personalized T-cell Directed Immunotherapies |
| TAU BIO-LOGIC | , | Website down Feb 2020 - May 2020, seems to be renamed TauC3 Biologics |
| Ardelyx | Waltham, MA | Gastrointestinal Therapeutics |
| Angsana Molecular and Diagnostics | , | Folded into Parkway Labs |
| ArrayUS Technologies | Burlington, ON | Non-invasive focused ultrasound therapy |
| Cognition Therapeutics | Pittsburgh, PA | Drug discovery & development |
| Invizyne | , | Renamed eXoZymes, Feb 2025 |
| , | Now part of Sanisure, Jun 2026 | |
| ID Biomedical | , | Acquired by GSK, Sep 2005, $1.7B |
| KALA BIO | Arlington, MA | Drug Delivery |
| Cello Therapeutics | San Diego, CA | Nanoparticle Delivery Platform |
| Xenometrics | , | Acquired by Citoxlab, Oct 2017 |
| SignalChem Biotech | Richmond, BC | Small Molecules |
| Acrymed | , | Bought by Halyard (Halyard fka Kimberly-Clark Healthcare) |
| Lotus Tissue Repair | , | Acquired by Shire, Jan 2013, $49.3M + $275M milestones |
| CMD Medtech | Columbus, OH | Medical Device Development |
| TearScience | , | Acquired by J&J, Nov 2017 |
| SCARLETRED | Cambridge, MA | Skin Imaging Software |
| , | business filings late Oct 2023 - Oct 2025 | |
| MultiCell Technologies | , | Effectively bankrupt, Mar 2018 |
| Innovative Spinal Design | , | Renamed Atlas Spine |
| Venaxis | , | Changed name to Bioptix, Dec 2016 |
| Civetta Therapeutics | , | Bankrupt, Dec 2023 |
| NAEJA-RGM Pharmaceuticals | , | No news 2017 - 2024; Reincarnation of NAEJA Pharmaceuticals post-bankruptcy |
| TorreyPines Therapeutics | , | Bankrupt 2009, Assets transferred to Calicimedica |
| Stargazer Pharmaceuticals | , | Website down Apr 2022 - Jul 2022 |
| Mediatech | , | Now Cellgro |
| BlueWind Medical | Herzliya, Israel | Neurostimulation Implants |
| TransGen Biotech | Beijing, China | Molecular and cellular biology reagents for scientific research, raw materials for molecular diagnostics |
| Mitokinin | , | Acquired by AbbVie, Oct 2023, $110M + $545 milestones |
| Conkin Surgical Instruments | Vancouver, BC | Valtchev Uterine Mobilizer and gynecology instruments |
| Klifo | Glostrup, Denmark | Drug Development Consultancy |
| , | Acquired by Galecto, Nov 2025 | |
| Sebacia | , | Website down Dec 2020 - Mar 2021 |
| GenPath Pharmaceuticals | , | Changed name to AVEO Oncology, Mar 2005 |
| NuCryo Vascular | , | Website hijacked Sep 2021; Boston Scientific bought Cryosvasc, stopped production. Old employees obtained rights and re-launched as NuCryo Vascular |
| OncoBindi | , | Just buzzwords on website Dec 2016 - Dec 2020 |
| Aliada Therapeutics | , | Acquired by AbbVie, Dec 2024 |
| Visiox Pharmaceuticals | , | Merged with Ocuvex Therapeutics, Aug 2024 |
| PRCXI Biotechnology | Suzhou City, China | Automated Pipetting |
| Foresight Biotherapeutics | , | Bought by Shire, Aug 2015, $300M |
| Ferndale Pharma Group | Ferndale, MI | Small Molecules, Contract Manufacturing |
| PolyTherics | , | Joined Antitope to become Abzena |
| NorTech Life Sciences | Maple Grove, MN | Medical Device |
| Zecardio Therapeutics | Barcelona, Spain | Cardiovascular Analysis Technology |
| |
Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis la |
| , | Website down Nov 2025 - Apr 2026 | |
| Nanoferix | , | Renamed Pendant Biosciences |
| XBiotech | Austin, TX | Antibody Therapy |
| Ximedica | Providence, RI | Medical Device Services |
| Macrocure | , | Merged into Leap Therapeutics |
| BioVersys | Basel, Switzerland | Drug Discovery |
| Biomedical Systems | , | Acquired by ERT, Sep 2017 |
| Vesper Bio | Copenhagen, Denmark | Oral Therapy for Frontotemporal Dementia |
| Neuavi | , | Acquired by Codman Neuro, Apr 2017 |
| Ikaria | , | Acquired by Mallinckrodt, Apr 2015 |
| PneumRx | , | Acquired by BTG plc, Dec 2014, $475M |
| BlueHaven Therapeutics | Allschwil, Germany | Radionuclide therapies for the treatment of solid tumors |
| , | Shut down Dec 2024; Sold all IP to Ginkgo, Apr 2023 | |
| Brecon Pharmaceutical | , | Acquired by AmerisourceBergen Mar 2006 $28M, Merged with Anderson Packaging Jun 2012, Acquired by Frazier Apr 2013 and merged with Packaging Coordinators Inc. (Frazier) |
| Alcami | Morrisville, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Pantherna Therapeutics | Hennigsdorf, Germany | Nanoparticle Delivery for mRNA drugs |
| Synubi Pharmaceuticals | , | 10-yr Sideline |
| Ectin Research | , | Website down Apr 2025 - Sep 2025 |
| ADMA Biologics | Ramsey, NJ | Biologics |
| Outpost Medicine | , | Website down Apr 2020 - Oct 2020 |
| PCI Pharma Services | Hay-On-Wye, UK | Contract Manufacturing, Services |
| Cyclica | , | Acquired by Recursion, May 2023, $40M |
| MTG Biotherapeutics | , | CEO gone for a year, company website still lists him. Not a registered CA business |
| Leuko | Madrid, Spain | Non-Invasive White Blood Cell Monitoring |
| Talis Biomedical | , | |
| Bioforum | Ness Ziona, Israel | Clinical Data Insights |
| Proteorex | , | Gone Nov 2017 |
| Thermo Fisher | Eugene, OR | Molecular Biology & Biotech Lab Products |
| Xueji Biotechnology | Suzhou, China | Stem Cells for Bleeding Disorders |
| Genexa | , | Shut down before Nov 2023 |
| BioNovion | , | Bought by Aduro Biotech, Sep 2015, $32.5M |
| , | Filings late Jun 2025 | |
| , | Website down Jan 2026 - Mar 2026 | |
| ScalmiBio | , | Acquired by ALX Oncology, Oct 2021 |
| Merganser Biotech | , | Not sure if active Sep 2020 - Dec 2020 |
| Canfield Scientific | Biefeld, Germany | Medical Imaging, Clinical Research Services |
| Relievant Medsystems | , | Acquired by Boston Scientific, Nov 2023, $850M |
| pSivida | , | Rebranded as EyePoint Pharmaceuticals, Mar 2018 |
| Neomics Pharmaceuticals | ZZ, France | T Cell Based Therapy |
| PrognosDx Health | , | Website gone Jun 2016 |
| AV Therapeutics | , | Penny Stock, no idea what happened |
| Ortho Development | Draper, UT | Ortho Implants |
| Laverock Therapeutics | London, UK | Programmable Cell Therapies |
| AexeRNA | , | Acquired by BioNTech, Nov 2023 |
| Intercytex | , | Liquidated |
| Kerafast | Newark, CA | Reagents for the Greater Good |
| Iconic Therapeutics | , | Acquired by Endpoint Health, Jun 2022 |
| Eutheria Bioscience | , | Shut down Sep 2024; Website down Apr 2024 - May 2024 |
| Bionova Scientific | The Woodlands, TX | Full-service Biologics CDMO |
| Myelo-JAK Biomarkers | , | Website Gone, Nov 2016 |
| TriLink Biotechnologies | San Diego, CA | Custom Nucleotides |
| ADS BIOTEC | Glasgow, UK | Lab Instruments, Consumables |
| Fujifilm Diosynth | Hillerød, Denmark | Biologics Development & Manufacturing |
| Exela Pharma Sciences | Hyderabad, India | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Imgen Biosciences | , | Business license revoked Oct 2019, no filings since 2016 |
| Haselmeier | Baar, Switzerland | Auto-injectors |
| ProLung | , | Renamed Ioniq Sciences, May 2020 |
| Palliare | Galway, Ireland | Surgical Smoke Evacuation |
| Cellevate | Lund, Sweden | Nano-material for Upstream Biomanufacturing |
| Atoxin Biotech | , | Website down Jan 2020 - Jun 2020; Residential Address, Jul 2019 |
| MetalloPharm | , | Sole 'employee' would not confirm existence |
| Emergo by UL | Austin, TX | Medical device consulting |
| Icagen (2) | , | Acquired by Ligand Apr 2020; Purchased Icagen assets from Pfizer |
| JANIX | , | Website for sale Jul 2022; Formerly in NV, fka JANIX Biosciences |
| Medical Metrics | Houston, TX | Imaging Services & Solutions |
| Nostrum Laboratories | Kansas City, MO | Generics |
| Orchid Orthopedic Solutions | Memphis, TN | Contract Medical Device Work |
| Axial Biotherapeutics | , | Renamed Axial Therapeutics, Nov 2020 |
| Santalis | , | Website down Jan 2020 - Feb 2020, Employees gone |
| Recursion Pharmaceuticals | New York, NY | Automated, software-based drug discovery |
| Aiolos Bio | , | Acquired by GSK, Feb 2024, $1B + $400M milestones |
| Sanofi | Cambridge, MA | Small Molecules, Biologics |
| Viamet Pharmaceuticals | , | Acquired by NovaQuest Capital Management, assets put into new company Selenity Therapeutics, Jan 2018 |
| Gotham Therapeutics | , | Acquired by 858 Therapeutics, Sep 2021 |
| panCELLa | , | Merged with Pluristyx, Oct 2022 |
| Dracen Pharmaceuticals | , | Not registered in CA, no real employees Jun 2025 |
| MYcroarray | , | Renamed Arbor Biosciences |
| Proteos | Kalamazoo, MI | Recombinant protein production, purification, and analysis services |
| Epixis | , | Acquired by VBI Vaccines |
| Unlearn | San Francisco, CA | Machine-learning technology that creates digital twins of patients in clinical trials |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| Inspirion Delivery Sciences | , | Website gone Apr 2020, Daiichi Sankyo cancelled licensing agreement Nov 2019 |
| DNA Worldwide | Frome, UK | DNA Testing |
| Promab Biotechnologies | Richmond, CA | Services and products in mRNA-LNP, CAR-T/CAR-NK, antibody & bispecific antibody, proteins & cytokines, nanoparticle formulation |
| superDimension | , | Acquired by Covidien May 2012 |
| Confluent Medical Technologies | Chattanooga, TN | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Clairvoyant Therapeutics | , | Acquired by Psyence, Sep 2024 |
| Treeline Biosciences | Watertown, MA | Molecular targets in oncology that are validated but difficult to drug |
| Alife | San Francisco, CA | AI-powered IVF |
| Guerbet | Villepinte, France | Contrast Agents, Injectors |
| Single Technologies | Stockholm, Sweden | Next-Gen Sequencing Platform |
| Pulse Therapeutics | , | Merged with ICHOR Vascular, Jan 2019 to become Euphrates Vascular |
| Atea Pharmaceuticals | Boston, MA | Nucleoside and nucleotide analogs to inhibit the viral RNA polymerase |
| Strand Diagnostics | , | Acquired by P4 Diagnostix, Feb 2020 |
| CODEX DNA | , | Renamed Telesis Bio, Oct 2022 |
| ProSciento | Chula Vista, CA | Clinical Research, Regulatory Development |
| Dimerix | , | Website hijacked Feb 2025; Acquired by Sun Biomedical, Jul 2015, they took this name |
| ABclonal | Woburn, MA | Antibodies & Related Services |
| BioLife Solutions | Bothell, WA | Chemical-Defined GMP Biopreservation Media |
| Rota Verpackungstechnik | Wehr, Germany | Fill/Finish Machines |
| Spero Therapeutics | Cambridge, MA | Anti-infectives |
| Raynovent Biotech | Guangzhou, China | Innovative therapies for respiratory and metabolic diseases |
| Piramal | Mumbai, India | CDMO |
| Friley Consulting | , | Renamed Integrated Bioanalysis, Oct 2020 |
| METiS Therapeutics | Cambridge, MA | AI Drug Discovery |
| ABC Testing | , | Renamed Certified Testing, Jul 2023 |
| Biomoles | , | Closed Sep 2017 |
| PureHoney Technologies | , | Renamed Momentum Biotechnologies, Aug 2023 |
| Aragen Life Sciences | Morgan Hill, CA | Cell line development, protein expression & purification, cell-based & biophysical assays, and in vivo models of disease. |
| Aspyrian Therapeutics | , | Rebranded Rakuten Aspyrian, Aug 2018 |
| Biomatrica | , | Acquired by Exact Sciences, Oct 2018 |
| Averica Discovery | , | Acquired by Neopharm Labs, Nov 2016 |
| Taproot Medical Technologies | Bothell, WA | Polymer Biomaterials |
| Wako Diagnostics | , | Acquired by Fujifilm, Dec 2016 |
| Anvyl | , | Website gone Jan 2021 |
| Courier Therapeutics | , | Acquired by Valo Health, Jul 2021 |
| Promethera Biosciences | , | Renamed Callaion |
| VitalScientific | , | Analytical Systems for Diagnostics |
| BioGX | Birmingham, AL | Molecular Diagnostics |
| Novum Pharmaceutical Research Services | Pittsburgh, PA | Clinical Research |
| SICGEN | Cantanhede, Portugal | Research Antibodies |
| Pierre Fabre | Toulouse, France | Oncology, derm / cosmetics |
| Silene Biotech | , | Acquired by NanoSurface Biomedical, Sep 2019 |
| BioSpring | Frankfurt, Germany | Manufacturing & Analytical Services |
| EPIX Therapeutics | , | Bought by Medtronic, Jan 2019, $316M |
| AffaMed Therapeutics | Beijing, China | Small Molecules, Monoclonal Antibodies |
| Lee's Pharmaceutical | Guangzhou , China | Small Molecules |
| , | Acquired by Sun Pharma, May 2025 | |
| 7TM Pharma | , | Gone |
| Gilson | Middleton, WI | Lab Supplies |
| AbCellera | Vancouver, BC | Therapeutic Antibody Discovery |
| Diurnal | , | Acquired by Neurocrine, Nov 2022, £48M |
| preclinics | Potsdam, Germany | Contract Research |
| Horama | , | Renamed Coave Therapeutics, Jul 2021 |
| SynVivo | Huntsville, AL | Physiological, cell-based microchip platform |
| Mpex Pharmaceuticals | , | Acquired by Axcan 2011, $17.5M + $195M milestones |
| Archimedic | West Chester, PA | Medical Device Consulting |
| Caribou Biosciences | Berkeley, CA | Cellular Engineering Tools (CRISPR) |
| Endosphere Surgical | , | Renamed New View Surgical, Aug 2016 |
| InCytu | , | Website gone Jul 2015 |
| Obexia | , | Gone |
| JSJ Pharmaceuticals | , | Changed name to Innocutis 2011 |
| TandemAI | Shanghai, China | AI to democratize the drug development process |
| Orexia | , | Acquired by Centessa |
| Vaccex | , | Website down Dec 2019 - Mar 2020, not active MA business Mar 2020 |
| Element Biosciences | San Diego, CA | Genetic analysis tools, Sequencing Tools |
| Firma Clinical Research | Elk Grove Village, IL | Clinical Research |
| Lumen Bioscience | Seattle, WA | Biologics |
| NTT Delivery Systems | , | Website Gone, Jul 2014 |
| Daiichi Sankyo | Osaka, Japan | Small Molecules |
| CyberHeart | , | Acquired by Varian, May 2019 |
| GenomeDx Biosciences | , | Renamed Decipher Biosciences, Jan 2019 |
| Brava Diagnostics | , | Merged with Mbio Diagnostics, renamed LightDeck Diagnostics Jul 2020 |
| TissUse | Berlin, Germany | Multi Organ chip |
| CoreBiome | , | Merged into Diversigen |
| Reshape Biotech | Copenhagen, Denmark | AI-powered petri and microtiter plate analysis |
| Fios Therapeutics | , | No website Jun 2021 - May 2023; been around since 2007 |
| Kardium | Burnaby, BC | Globe Mapping and Ablation System, for the diagnosis and treatment of atrial fibrillation |
| Immuni T | Montréal, QC | Flow Cytometry, Other Assay Services |
| Sugen | , | Acquired by Pharmacia & Upjohn, 1999, $650M stock; Shut down 2003 |
| Meryx | , | Website down Aug 2022 - Jan 2023 |
| Chameleon Biosciences | , | Website down Jan 2024 - Jul 2024 |
| SkinCure Oncology | Burr Ridge, IL | Image-Guided SRT |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| Mosanna Therapeutics | Basel, Switzerland | Small Molecule for Metabolic Obstructive Sleep Apnea |
| NuShores Biosciences | Little Rock, AR | Bone and tissue regeneration technologies |
| Vitesse Biologics | , | Owns Thunderbolt Pharma, no website Apr 2019 |
| BNC Korea | , | Domain taken over Oct 2021 - Jan 2022 |
| , | Website down Jun 2025 - Dec 2025 | |
| , | Shut down May 2025 | |
| Navigen Pharmaceuticals | , | Website gone Aug 2020 - Mar 2021 |
| VasoGenix | , | Failed, tried to come back, not sure of status |
| Physio-Control | , | Bought by Stryker, Feb 2016, $1.28B - became Stryker Emergency Care |
| Myriamed | Goettingen, Germany | Cells for Drug Development |
| Worldwide Clinical Trials | São Paulo, Brazil | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| OneThree Biotech | , | Website down Sep 2024 - Oct 2024, CEO gone, Employees on LI peaking in past tense, Oct 2024 |
| NB Therapeutics | , | Gone |
| Callisto Pharmaceuticals | , | Merged with Synergy Pharmaceuticals, Jan 13 |
| Clinical Trials of North Carolina | , | Website Gone, Sep 2017 |
| Oculus Innovative Sciences | , | Renamed Sonoma Pharmaceuticals, Dec 2016 |
| Neotech | , | Website down Jan 2019 |
| Cambridge Pharma | , | Rolled into parent, SMC |
| MedaRed | , | Renamed Therini Bio, Feb 2020 |
| GeneMedicine | Seoul, Korea | CDMO, Oncolytic Viruses |
| RegenoCELL Therapeutics | , | Presumed gone |
| iotaMotion | St. Paul, MN | Cochlear Implant Insertion Robots |
| Galaxy Medical | , | Merged into Galvanize Therapeutics, 2022 |
| Biocious Life Sciences | , | Now Agilent |
| Assurex Health | , | Acquired by Myriad Genetics, Sep 2016, $200M, renamed GeneSight |
| , | Website down Jan 2026 - May 2026 | |
| Firalis Molecular Precision | Huningue, France | Biobanking, Sequencing, Mass Spec, Omics, Assay Development |
| Ionicon Analytik | Innsbruck, Austria | PCR, Lab Equipment |
| Grace Therapeutics (1) | , | Acquired by Acasti, Aug 2021 |
| Daxor | Oak Ridge, TN | Blood Volume Measurement |
| Bayer | Berlin, Germany | Small Molecules |
| SunTech Medical | Morrisville, NC | Blood Pressure Monitoring |
| Caron Scientific | Marietta, OH | Hoods, refrigerators, lab equipment |
| Admetrx | , | Closed 2010, Assets acquired by CeeTox |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Pernix Therapeutics | , | Filed Chapter 11 Bankruptcy, Feb 2019; reborn as Currax Pharmaceuticals |
| AMRA Medical | Linköping, Sweden | MRI Body-composition analysis |
| NanoLive | Tolochenaz, Switzerland | Cellular Imaging |
| Recordati | Ringaskiddy, Ireland | Small Molecule Manufacturing |
| Allosterix Pharmaceuticals | , | Website from about 1999 |
| Omne Possibile | , | Website down Jan 2024 - Jul 2024 |
| Johnson and Johnson Innovative Medicine | Horsham, PA | Small Molecules, Biologics |
| Ariceum Therapeutics | Berlin, Germany | Novel drugs for systemic targeted radiation therapy |
| Micron Solutions | Fitchburg, MA | Electrocardiography Software |
| Fulgent Pharma | El Monte, CA | Chemotherapy drugs through nanoencapsulation and innovative new drug candidates |
| Tanai Therapeutics | , | Obesity Treatment |
| Human Cell | Naperville, IL | Contract Manufacturing, Research Reagents |
| Ryne Biotechnology | , | Renamed Kenai Therapeutics, Feb 2024 |
| Imagen Biopharma | , | Renamed Cue Biopharma, Nov 2016 |
| Axya medical | , | Gone 2012 |
| Kareus Therapeutics | , | Website Gone, Mar 2017 |
| , | Website down, COO gone Oct 2025 | |
| Revivocell | Cheshire, UK | AI Neurotoxicity Testing |
| Metrad Biosystems | , | Website gone |
| Llama Therapeutics | , | Renamed Autobahn Therapeutics |
| Symbiomix Therapeutics | , | Acquired by Lupin, Oct 2017, $150M |
| Diffusion Pharmaceuticals | , | Merged with EIP Pharma, Aug 2023, renamed CervoMed; Merged with Restorgenex, Dec 2015 |
| TheraProteins | , | Website down Aug 2024 - Feb 2025 |
| IntelliCell Biosciences | , | Website gone Jan 2019 |
| Archer Biosciences | , | Renamed Cortice Biosciences |
| Fosun Pharma | Singapore, Singapore | Small molecules, diagnostics, traditional |
| TriPhos Therapeutics | , | Main employee gone since Nov 2020, still on website Jul 2021 - Dec 2022 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| ProteoDesign | , | Renamed Splice Bio, Sep 2020 |
| Cartiva | , | Acquired by Stryker as part of Wirght Medical, Nov 2019 |
| Valo Therapeutics | Helsinki, Finland | Oncolytic Virus, Peptide |
| Serometrix | , | More of an aspiration than a company |
| Cartana | , | Bought by 10X Genomics, Oct 2020 |
| Pangea Laboratory | Tustin, CA | Cancer Diagnostics |
| Xcovery | Miami, FL | Targeted cancer therapeutics |
| Celixx | Jeju, Korea | Gene Therapies, Peptides, CMO Services, Small Molecules |
| Targanox | , | Website hacked, employees who are gone still appear on Website, May 2016 |
| COOL-BIO | , | Gone |
| Rafael Pharmaceuticals | , | Renamed Cornerstone Pharma, May 2022; fka Cornerstone Pharma |
| amaxa | , | Acquired by Lonza, Jul 2008 |
| Admirx | , | Renamed Q32 Bio, Apr 2020 |
| Commense | , | Website gone Nov 2019 - Feb 2020, still filings business reports Mar 2020 |
| X-37 | , | Website down Oct 2022 - Apr 2023 |
| The TIM Company | , | Renamed InnoGI Technologies, Feb 2024 |
| , | Acquired by hVIVO, Jan 2025 | |
| , | Acquired by Boehringer Ingelheim, Jul 2019, €225M + €100M Milestones | |
| Neose | , | Gone |
| |
Shanghai, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| Sania Therapeutics | London, UK | CNS Treatments |
| Bespak | Holmes Chapel, UK | CDMO focused on inhaled and nasal drug delivery devices and drug-device combination products |
| STA Pharmaceutical | Shanghai, China | API manufacturing |
| Viant Medical | Wheeling, IL | Contract Medical Devices |
| Cogent Biosciences | Boulder, CO | Cellular immunotherapies |
| Imago Biosciences | , | Acquired by Merck, Jan 2023, $1.35B |
| PharmaNet/i3 | , | Renamed inVentiv Health Clinical |
| BioinfoScientist | , | Website down Mar 2025 - Aug 2025 |
| Celentyx | Birmingham, UK | CLRO assay services for immuno-oncology, autoimmunity & inflammation, neuroinflammation, and fibrosis |
| GNA Biosolutions | , | Now part of HP Health |
| Cellex Life Sciences | , | Renamed ILIAS Biologics |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| AN2 Therapeutics | Menlo Park, CA | Novel medicines targeting infectious diseases |
| ABEC | Springfield, MO | Bioprocess engineering, equipment, services including stainless steel and single use bioreactors & fermenters. |
| Amorsa Therapeutics | , | Acquired, 2022 |
| Notable Labs | , | Chapter 7 Bankruptcy, Oct 2024; Merged with VBL Therapeutics, Oct 2023 |
| PCI Pharma Services | Mississauga, ON | Contract Manufacturing, Services |
| Intact Genomics | St. Louis, MO | PCR kits |
| Vernay | Milledgeville, GA | Fluid Control Solutions |
| ZyStor | , | Bought by BioMarin, closed |
| LabMinds | , | Rolled into Accroma Labtec, Nov 2023 |
| Adhesion Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Celeris Therapeutics |
| AddGraft Therapeutics | , | Website Down May 2024 - Nov 2024 |
| BA Sciences | Salem, NH | Analytical Services |
| Medivative Technologies | , | Acquired by Kimball Electronics, Jul 2016 |
| Wellstat Group | , | Website down Sep 2023 - Mar 2024 |
| Vertiflex | , | Acquired by Boston Scientific, Jun 2019, $465M |
| BioTheryX | San Diego, CA | Small Molecules |
| Lavipharm | East Windsor, NJ | Small molecules |
| Curemark | Rye Brook, NY | Enzyme Treatment |
| Xiangxue Life Sciences | Guangzhou, China | TCR based Therapies |
| Abintus Bio | , | Sold assets May 2025, winding down; Website down Mar 2025 - Jun 2025 |
| NuSirt Biopharma | , | All employees have more important jobs, no progress 2015-2022; fka NuSirt Sciences |
| TBG Diagnostics | , | Seems shut down 2023, website taken over by different biotech |
| Medarex | , | Bought by BMS 2009 |
| QPillars | Zurich, Switzerland | Intelligent software infrastructure for life sciences laboratories |
| Tesaro | , | Acquired by GSK, Jan 2019, $5.1B |
| Clarapath | Hawthorne, NY | Pathology Device |
| Censo Biotechnologies | , | Merged with Axol Bioscience, Mar 2021 |
| Y's Therapeutics | , | Website Gone |
| ABBA Therapeutics | , | Founder extradicted for stealing trade secrets |
| BioZax | , | Not a registered business in NY, website gone Jan 2019 |
| Natera | San Carlos, CA | Prenatal Testing |
| MyBiotech | Überherrn, Germany | Bioreactors |
| Ufovax | , | Renamed Uvax Bio? |
| MabVax Therapeutics | , | Sold off assets to BioNTech in bankruptcy, May 2019 |
| 3Clinical Research | , | Acquired by Parexel, Mar 2004 |
| iovera | Tampa, FL | Cold-treatment for nerves |
| Drucker Diagnostics | Port Matilda, PA | Centrifuges, other lab equipment |
| Aquestive Therapeutics | Warren, NJ | Drug Delivery Technology |
| Applikon Biotechnology | , | Acquired by Getinge, Jan 2020 |
| Ubiquigent | , | Shut down Aug 2025, may have sold IP |
| Easthorn | , | Acquired by Novotech, Jan 2023 |
| Beren Therapeutics | Thousand Oaks, CA | Treatment for impaired intracellular cholesterol trafficking |
| , | Website down Sep 2025 - Dec 2025 | |
| Affinimark Technologies | , | Gone |
| InterPharma One | , | Website down Feb 2024 - Mar 2024 |
| Gentell | Yardley, PA | Wound Care |
| Akubio | , | Bankrupt Sep 2007 |
| Tryp Therapeutics | , | Acquired by Exopharm, May 2024 |
| Intrinsic LifeSciences | La Jolla, CA | In-Vitro Diagnostics |
| Quiver Bioscience | Cambridge, MA | Precision Genetic Medicine Services |
| Topera Medical | , | Acquired by Abbott, 2014, renamed Abbott Electrophysiology |
| NextPharma | Goettingen, Germany | Contract Research & Development |
| Aegis Therapeutics | , | Acquired by Neurelis, Dec 2018 |
| Surface Oncology | , | Acquired by Coherus, Sep 2023, $65M |
| Zacharon Pharmaceuticals | , | Acquired by Biomarin Jan 2013 |
| Meridian BioGroup | , | Acquired by Pace Life Sciences, Aug 2022 |
| Codex Therapeutics | , | No info since 2013, not registered in MD |
| Best Vascular | , | Now Best Vascular Novoste |
| uniQure | Amsterdam, Netherlands | Gene Therapy |
| Automata | London, UK | Lab workflow automation platform |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Lonza | Walkersville, MD | Contract Manufacturing, Reagents, Stem Cells, Services |
| Emergent BioSolutions | Princeton, NJ | Biologics, Contract Manufacturing, Biodefense |
| Porex Surgical | , | Acquired by Stryker, Sep 2010 |
| Kiq | , | Acquired by Unum Therapeutics, Jul 2020 |
| Tentarix Biotherapeutics | San Diego, CA | Logic-Gated Multivalent Molecule Technology |
| Aileron Therapeutics | , | Renamed Rein Therapeutics, Jan 2025 |
| Cresset Discovery Services | Litlington, UK | Computational Solutions for Drug Discovery |
| Nimbus Discovery | , | Changed name to Nimbus Therapeutics, Mar 2015 |
| Onyvax | , | Assets Apparently Acquired |
| Perlara PBC | , | Shut down Feb 2019 |
| Bendalis | Oberhaching, Germany | Generic Oncology Products |
| LUCA Biologics | , | Seems folded back into parent company, May 2024; Not registered in CA, Mar 2023 |
| Concept Inc | , | Bought by BMS, 1990; sold to CONMED Dec 1997 |
| Formurex | Stockton, CA | Contract Research |
| Altasciences | Overland Park, KS | Contract Research |
| Ginkgo Bioworks | Boston, MA | Engineered Organisms |
| Agomab Therapeutics | Antwerpen, Belgium | Agonistic monoclonal antibody molecules |
| Pipeline Therapeutics | , | Renamed Contineum Therapeutics, Dec 2023 |
| Grid Biosciences | New Territories, China | Vaccines |
| Black Belt Therapeutics | , | LinkedIn pointing to Alesta Therapeutics Oct 2021; New Sep 2018, no website Dec 2018 - Aug 2021. Reincarnation of Tusk Therapeutics post-Roche acquisition |
| Cellesce | , | Website down Apr 2025 - Jul 2025; Acquired by Molecular Devices, Jul 2023 |
| Celsion | , | Renamed Imunon, Sep 2022 |
| Anoat Therapeutics | , | No website, Aug 2023 - Jan 2025 |
| Orchid Orthopedic Solutions | Farmington Hills, MI | Contract Medical Device Work |
| Ramus Medical | Sofia, Bulgaria | Clinical Research |
| EpigenDx | Hopkinton, MA | Genomic & Epigenomic Services |
| OticPharma | , | Merged with Tokai Pharmaceuticals, May 2017, Changed name to Novus Therapeutics |
| Augmenta Bioworks | Menlo Park, CA | Antibody Discovery, Target Identification Services |
| Mevion Medical Systems | Littleton, MA | Radiation Therapy |
| Nesher Technologies | , | Shut down Oct 2017 |
| Retroject | , | Seems gone |
| VLST Corp | , | Wound Down, Jun 2013 |
| CTK Biotech | Poway, CA | Diagnostics |
| Diag-Nose.io | Notting Hill, Australia | Chronic Rhinosinusitis diagnostic and treatment platform |
| Cellf BIO | , | Website taken over Jan 2019 |
| US Diagnostics | , | Bought by Alere, Jul 2015, $60M |
| Genomics Medicine Ireland | , | Website down Dec 2022 - Apr 2023 |
| |
Killorglin, Ireland | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| DoveTree Medicines | , | |
| KaNDy Therapeutics | , | Acquired by Bayer, Sep 2020, $425M |
| Zymetis | , | Acquired by AE Biofuels 2011 |
| Genomics PLC | Oxford, UK | Human Genetics Platform |
| Aclara Biosciences | , | Bought by ViroLogics, Dec 2004, $160M |
| Drug Free Therapeutix | , | Website gone Jun 2022 |
| Omnicare Clinical Research | , | Now Theorem Clinical Research |
| Evopoint Biosciences | Beijing, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Vivacy | Archamps, France | Aesthetic Medicine |
| Stella Diagnostics | , | Website down Apr 2023 - Sep 2023 |
| Orthros Medical | Raalte, Netherlands | VHH based therapeutics and diagnostics |
| Cardica | , | Renamed Dextera Surgical, Jun 2016 |
| Ranfac Corp | Avon, MA | Marrow/Tissue sampling, Catheters, Biopsy Needles, etc |
| Eccogene | Shanghai, China | Small Molecules |
| Mint Pharmaceuticals | Mississauga, ON | Generics |
| , | Website down Jul 2025 - Dec 2025 | |
| Strohtech | , | Renamed Apex Bioscience, 1994 |
| Orthogonal LLC | Chicago, IL | Medical device software |
| Zymo Research | Irvine, CA | Epigenetics, DNA, RNA research products |
| StemoniX | , | Merged with Cancer Genetics, Mar 2021, became Vyant Bio |
| Veranome Biosystems | , | Website down Nov 2023 - Mar 2024, LI page gone Nov 2023 - Mar 2024 |
| NeuroRepair | , | Business revoked by CA, 2007 |
| Innovative Cellular Therapeutics | Rockville, MD | CAR-T Therapies |
| Zelos Therapeutics | , | No site |
| Arcede Pharma | , | Liquidation, Jul 2024 |
| Opexa Therapeutics | , | Merged into Acer Therapeutics, Sep 2017 |
| Crystal Bioscience | , | Acquired by Ligand Pharmaceuticals, Oct 2017, $25M |
| Tanda BioTech | Chicago, IL | Bioproduction Technology |
| Circassia Pharmaceuticals | , | Renamed NIOX, Sep 2022 |
| |
Kitchener, ON | Select Rapid Novor for expert antibody discovery and characterization, utilizing advanced mass spectrometry for unparalleled precision. |
| MantraPharma | Lévis, QC | Generics |
| Alcresta Pharmaceuticals | , | Renamed Alcresta Therapeutics, Jun 2016 |
| ResVerlogiX | San Francisco, CA | Small Molecules |
| Arisaph Pharmaceuticals | , | Website under construction, Nov 2016-Feb 2018 |
| Akcea Therapeutics | , | Spun out of Ionis Pharmaceuticals, fully reacquired Aug 2020 |
| Onco3R Therapeutics | , | Renamed Coultreon Biopharma, Apr 2026 |
| Semarion | Cambridge, UK | Microcarriers for Adherent Cell Growth |
| , | Renamed First Atom Therapeutics | |
| Tangent Medical Systems | , | Closed |
| Optra Health | San Jose, CA | Medical Devices and Lab Automation, Life Science Informatics, Knowledge Automation and Big Data solutions and services |
| Third Wave Technologies | , | Acquired by Hologic Jun 2008 |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Pillar Biosciences | Natick, MA | Targeted next-generation sequencing (NGS)-based assays and software |
| Capua BioServices | , | Acquired by Olon, Jan 2019 |
| twoXAR Pharmaceuticals | , | Renamed Aria Pharmaceuticals, May 2021 |
| AB Science | Paris, France | Small Molecules |
| Amedra Pharmaceuticals | , | Acquired by Impax Laboratories, Mar 2015 |
| CELLID | Seoul, Korea | Immunotherapeutic Vaccines |
| Python Medical | , | Website down Nov 2019, late business filing 2020 |
| Midnight Pharma | , | No website Dec 2019 - May 2023 |
| Jiuzhou Pharma | Konstanz, Germany | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Sunol Molecular | , | Assets sold 2005 |
| AxeroVision | , | Website under construction, Aug 2020 - May 2021; GSK spinout |
| Crestone | Boulder, CO | Small molecules for bacterial infections |
| Memento Medicines | , | |
| Mellitus | , | Website taken over Nov, 2024; Business filings late Jun 2024 |
| Helix Diagnostics | , | Acquired by Bio-rad, Jul 2001 |
| Angiosonics | , | Shut down 2002 |
| Matrix Surgical | , | Website down Jul 2021 - Dec 2021 |
| Scil Technology | , | Acquired by Nanohale, Sep 2012, creating subsidiary Formycon |
| Arase Therapeutics | Boston, MA | Therapeutics targeting ADP-ribose Hydrolases |
| Variant Bio | Seattle, WA | Genomic Drug Discovery |
| TherOptix | , | No website Oct 2021 - May 2023 |
| Corimmun | , | Acquired by Janssen, Jun 2012 |
| PRA Health Sciences | , | Acquired by ICON plc., Jul 2021, $12B |
| Celerion | Tempe, AZ | Clinical Research |
| Pharmaron | Germantown, MD | Bioanalytical Services |
| Casma Therapeutics | Cambridge, MA | Autophagy-focused Treatments |
| Alcon | Mississauga, ON | Eye Care Products |
| Electra Therapeutics | South SF, CA | Therapies for immunological diseases and cancer |
| Wellspring Biosciences | , | Seems gone, Nov 2022 |
| Imagene AI | Tel Aviv, Israel | Image-based Biomarker Detection |
| D.E. Shaw Research | New York, NY | Drug Discovery Services |
| PLx Pharma | , | Bankrupt, winding down May 2023 |
| Altos Therapeutics | , | Gone Jun 2019 |
| Chemspeed Technologies | Füllinsdorf, Switzerland | Lab Automation |
| ILSUNG Pharmaceuticals | , | Website down Nov 2023 - Mar 2024 |
| Xynomic Pharmaceuticals | Shanghai, China | Small Molecules |
| , | No news 2020 - Dec 2025 | |
| MateraCor | , | Acquired by BioVentrix, Jan 2022 |
| Ember Therapeutics | , | Website gone Oct 2023, employees as well; Mariel Therapeutics merged into Ember, Mar 2015 |
| Baccuico | , | Renamed Bactobio |
| Helmer Scientific | Noblesville, IN | Manufacturer & Distributor of blood processing components |
| SteadyMed | , | Acquired by United Therapeutics, Aug 2018, $75M + $150M milestones |
| Molsoft | San Diego, CA | Drug Design Software |
| Bio-gene Technologies | Guangzhou, China | CAR T Cell Therapy |
| Roche | Laval, QC | Diagnostics |
| Chondropeptix | , | No real employees, Website under construction Aug 2025 |
| Abilita Bio | , | Renamed Abilita Therapeutics, Jun 2023 |
| ActivBiotics | , | Assets sold off Feb 2008 |
| Nia Therapeutics | Boston, MA | Neural interfaces for memory restoration |
| C-Ray Therapeutics | Beijing, China | Radiopharmaceuticals |
| OncoMed Pharmaceuticals | , | Merged with Mereo, Apr 2019 |
| Zynerba Pharmaceuticals | , | Acquired by Harmony Biosciences, Oct 2023, $60M |
| Uniogen | Turku, Finland | Diagnostics, Supplies |
| Johnson & Johnson MedTech | Danvers, MA | Medical Devices |
| Alimetrix | , | Acquired by Spectrum Solutions, Mar 2023 |
| STURQ Associates | , | Not a registered business, Feb 2025 |
| , | Renamed Ribonexus, Nov 2021 | |
| Neuraly | Gaithersburg, MD | PEGylated Small Molecule |
| Columbia Laboratories | , | Renamed Juniper Pharmaceuticals, Apr 2015 |
| Precisive Surgical | , | Merged with CARLSMED, Jul 2019 |
| , | Acquired by mining company; fka Anew Medical | |
| Allergy Immuno Technologies | , | Acquired by rubber company, 2003 |
| restor3d | Durham, NC | 3D printed implants and devices |
| neoX Biotech | , | Website down Feb 2025 - Jul 2025 |
| Hillal Biotechnology | , | Website down Feb 2025 - Jul 2025; fka Koek Biotechnology |
| MedGyn Products | Westmont, IL | OBG Devices |
| CRISPR Therapeutics | Boston, MA | CRISPR-Cas9 therapy |
| Torrent Pharmaceuticals | Ahmedabad, India | Generics |
| Acorn Cardiovascular | , | Liquidated May 2011 |
| Prosomnus | Pleasanton, CA | Sleep Apnea Mouthguard |
| |
Paris, France | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| PolyMicrospheres | Indianapolis, IN | Microparticles |
| Nanopareil | , | Acquired by Gamma Biosciences, Sep 2020 |
| HighRidge Medical | Westminster, CO | Spinal Surgery Systems |
| Theraclone Sciences | , | Licensed all assets out after phase 3 failure fka Spaltudaq |
| Kytogenics | , | Business revoked by NS, Nov 2014 |
| PharmAbcine | Daejeon, Korea | Antibodies |
| E-motion Medical | , | Website gone Dec 2019 - Aug 2021 |
| Citryll | Oss, Netherlands | Treatments targeting the formation of neutrophil extracellular traps |
| Certara | Clayton, MO | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| A2 Biotherapeutics | Agoura Hills, CA | Immunotherapy |
| Relay Therapeutics | Cambridge, MA | Motion-based Drug Design |
| Illustris Pharmaceuticals | , | Website down Sep 2022 - Feb 2023 |
| Mologen | , | Liquidating, May 2020 |
| Jeyou Pharma | Shanghai, China | Drug Discovery Platform |
| BalinBac Therapeutics | , | Gone 2018 |
| KorvaLabs | , | Acquired by Curative, May 2020 |
| Iterative Scopes | , | Renamed Iterative Health, Oct 2022 |
| Oclassen Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, Feb 1997 |
| Ronovo Surgical | Shanghai, China | Minimally-invasive Surgical Devices |
| A-Mansia Biotech | , | Website down Apr 2023 - Sep 2023 |
| Soin Neuroscience | , | Seems like one guy |
| EQL Pharma | Lund, Sweden | Generics |
| Lassen Therapeutics | San Diego, CA | Anti-IL-11 Antibodies |
| Thermo Fisher | Carlsbad, CA | Molecular Biology & Biotech Lab Products |
| Afimmune | Dublin, Ireland | Bioactive Lipid Technology |
| Theraly Fibrosis | , | No website May 2023 - Dec 2024 |
| Polpharma Biologics | Duchnice, Poland | Biosimilars |
| Fluoxivid Diagnostics | , | Single person company with no location |
| Parcell Labs | , | Website Gone, Oct 2016 |
| Innocutis | , | Acquired by Cipher Pharmaceuticals, Apr 2015 |
| Resonetics | Davis, CA | Contract Medical Device Manufacturing & Development |
| MDC Associates | Beverly, MA | Regulatory Affairs, Quality Systems, CRO Services, and Commercial Support |
| iOmx Therapeutics | Martinsried, Germany | Cancer Immunotherapy |
| Biomax Informatics | , | Acquired by Labvantage |
| Aronex Pharmaceuticals | , | Acquired by Antigenics, Apr 2001 |
| GT Biologics | , | Renamed 4D Pharma Research |
| Cagent Vascular | Wayne, PA | Balloon Catheter |
| Medipacs | , | Shut down Jul 2024 |
| Delta Pharma | , | Renamed Randstadt Pharma |
| Oncologic | , | Changed name to Aduro Biotech, Jun 2008 |
| Mindflow Design | , | Now part of MPE |
| QR Pharma | , | Renamed Annovis Bio, Jun 2019 |
| ClinAssess | Leverkusen, Germany | Clinical Research |
| , | Shut down late 2025; Website down Aug 2025 - Dec 2025 | |
| ClinOne | Needham, MA | Clinical Patient Platform |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Teikoku Pharma | San Jose, CA | Drug Delivery Systems |
| MetaMol Theranostics | , | Gone |
| Heatwurx | , | Renamed Processa Pharmaceuticals, Oct 2017 |
| Nascent Biologics | , | Changed to Nascent Biotech |
| Marauder Therapeutics | , | Changed name to CAMP4 Therapeutics, Mar 2018 |
| MAC Clinical Research | Blackpool, UK | Clinical Development |
| Pfizer | Tokyo, Japan | Small Molecules, Biologics, Vaccines |
| X-Vax Technology | , | Website gone Nov 2023 - Apr 2024 |
| Viscient Biosciences | San Diego, CA | 3D tissue technology to discover and develop drugs |
| Medicilon | Shanghai, China | Preclinical research for pharmaceutical enterprises, research institutions, and scientific researchers |
| StemSynergy Therapeutics | , | No business filings, Sep 2011 - Aug 2024 |
| AiViva BioPharma | Irvine, CA | JEL delivery technology |
| 3D Biomatrix | , | Closed down |
| Transposagen Biopharmaceuticals | , | Renamed Hera BioLabs, 2020 |
| Faust Pharmaceuticals | , | Renamed Domain Therapeutics, 2008 |
| Creabilis | , | Acquired by Sienna Biopharmaceuticals, Dec 2016, up to $150M |
| Metalytics | Cary, NC | Digital Twins for Cell Culture Operations |
| RotaChrom Technologies | Irvine, CA | Centrifugal Partition Chromatography manufacturer and method developer |
| Garwood Medical Devices | Buffalo, NY | Prevention of infection in joint replacement |
| Biotectix | , | Acquired by Heraeus Medical Components, Aug 2017 |
| Steris | Mentor, OH | Contamination Control |
| Celula | , | Acquired by NeoSeq |
| Fujifilm Diosynth | Billingham, UK | Biologics Development & Manufacturing |
| Experimur | , | Dated website, Emails bouncing from Mar 2017 - Feb 2018 |
| RTS Life Science | , | Bought by Brooks Automation Apr 2011 |
| LumeBio | , | No website Oct 2019 - Aug 2021 |
| Virion Biotherapeutics | , | Website down Jan 2021 - May 2021; fka Virion Health |
| Actelion Clinical Research | , | Was part of Actelion Pharmaceuticals |
| LakePharma | , | Acquired by Curia, Jul 2021 |
| , | Website down Oct 2025 - Feb 2026 | |
| Endotis Pharma | , | Founded in 2003. No info |
| Lakefront Biotherapeutics | Romainville, France | Drug & Antibody Therapy Discovery |
| s-TARget Therapeutics | , | Website taken over May 2021 - Dec 2022 |
| Glyphic Biotechnologies | New York, NY | Protein Sequencing Platform |
| BEBIG Medical | St. Gangloff, Germany | Radiation Therapy Products |
| Lumenis | Seoul, Korea | Energy-based medical treatments |
| Magnitude Biosciences | Sedgefield, UK | C Elegans Data Platform |
| UNION therapeutics | Hellerup, Denmark | Small Molecules |
| Paraza Pharma | Cambridge, MA | Collaboration-based research model with in-house Chemistry, Biology and DMPK (includes proteomics and small molecule biomarker analysis) expertise |
| VARIAGENICS | , | Acquired by Hyseg Pharmaceuticals, Nov 2002, $55.9M |
| Nuwellis | Eden Prairie, MN | Heart Failure Device |
| OriGen Biomedical | Austin, TX | Cell Culture Products |
| NuChem Therapeutics | , | Renamed NuChem Sciences, Apr 2021 |
| PersImmune | , | CEO gone, delinquent business filings May 2022 |
| ProteoGenix | Schiltigheim, France | Custom peptide synthesis, polyclonal and monoclonal antibody production, recombinant protein production, and custom gene synthesis |
| Tandem Life | , | Acquired by LivaNova, Feb 2018 |
| Glox Therapeutics | Glasgow, UK | Precision antibiotics based on protein bacteriocins |
| , | Renamed Kyntra Bio, Jan 2026 | |
| iRhythm Technologies | San Francisco, CA | Remote heart analysis |
| VIMRx Pharmaceuticals | , | Changed name to Nexell Therapeutics, May 1999 |
| , | Website taken over, Jan 2026 | |
| Sun Valley Research Center | Imperial, CA | Clinical Research |
| Re-Pharm | , | Appears to have been folded into Cresset Discovery Services |
| Novoteris | , | Website Down Jan 2022 - Jul 2022 |
| Corautus Genetics | , | Merged with VIA Pharmaceuticals, Jun 2007 |
| Caisson Biotech | , | Website down Oct 2024 - Nov 2024 |
| Renovacor | , | Acquired by Rocket Pharmaceuticals, Dec 2022; Went public via SPAC Sep 2021 |
| Charles River Laboratories | Wilmington, MA | Research Animal Models and Preclinical Research |
| Raindance Technologies | , | Acquired by Bio-Rad, Jan 2017 |
| Green Mountain Antibodies | Burlington, VT | Antibody Products & Services |
| , | No employees on Linkedin May 2026; Website gone Feb 2026 - May 2026 | |
| GSK | Montrose, UK | Small Molecules, Vaccines, Biologics |
| Valence Health | , | Acquired by Evolent Health, Oct 2016 |
| Spectral Diagnostics | , | Changed name to Spectral Medical, Dec 2014 |
| MMJ International Holdings | , | Website down May 2021 - Sep 2021 |
| Aurin Biotech | , | Website under construction Apr 2020 - Aug 2021 |
| Adgero Biopharmaceuticals | , | Merged into Delmar Pharmaceutical, Aug 2020 |
| Sandoz | Princeton, NJ | Generics, Biosimilars |
| Access Vascular | Billerica, MA | Hydrogel-based devices to improve venous access |
| AXON Neuroscience | Larnaca, Cyprus | Tau Vaccine |
| Curry Pharmaceuticals | , | Closed 2008 |
| Agilent | Seoul, Korea | High-Throughput Screening Equipment, Imaging instruments |
| , | Website down Jan 2026 - May 2026 | |
| , | Website down Aug 2025 - Jan 2026 | |
| Helicon Therapeutics | , | Merged with Dart Neuroscience |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Epitopea | Cambridge, UK | Therapeutics targeting a novel class of tumor-specific antigen |
| Omega Therapeutics | , | Website gone May 2025; Bankrupt, Feb 2025 |
| HexaScreen | , | No info since 2010, Dates website, no Employees on LI |
| MitoStem | , | Seems gone |
| Poba Medical | Flagstaff, AZ | Medical balloon developer and manufacturer |
| |
Shanghai, China | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| Advanced Biosystems | , | Renamed AFG Solutions, Nov 2004 |
| STORM Therapeutics | Cambridge, UK | Small molecule inhibitors of RNA-modifying enzymes for the treatment of cancer |
| Aldeyra Therapeutics | Lexington, MA | Aldehyde-trap therapies |
| BioTransplant Inc | , | Bankrupt, 2003 |
| Azee Pharmaceuticals | , | Not a registered business in CA Feb 2025 |
| Modulus Oncology | , | Website down Mar 2023 - Oct 2023 |
| , | Website taken over Mar 2026 | |
| GEROPHARM | St. Petersburg, Russia | Large drug maker |
| Encoded Therapeutics | South SF, CA | Gene Therapy |
| ImmunogenX | , | Merged with First Wave BioPharma, Mar 2024; Also acquired Alvine Pharma assets Mar 2016 |
| AFG Solutions | , | Seems gone, fka Advanced Biosystems |
| Key Neurotek | , | Out of business (Bloomberg BusinessWeek) |
| Karkinos Healthcare | Mumbai, India | Ondo diagnostics |
| Veeva Systems | Shanghai, China | Life Science Software |
| OliPass | Gyeonggi, Korea | Peptide nucleic acid derivatives |
| HotSpot Therapeutics | Boston, MA | Small Molecules designed for Distinct Protein Domains |
| VeriSIM Life | San Francisco, CA | Biosimulations |
| Van Hoef Consulting | , | Website taken over by porn, May 2020 |
| Calcico Therapeutics | , | Website gone Apr 2020 - Aug 2021, no info |
| SeromYx Systems | Woburn, MA | Systems Serology |
| FusionBio | , | Website down Sep 2025 |
| KBI Biopharma | Durham, NC | Contract Development & Manufacturing |
| Biotrin International | , | Renamed Diasorin? |
| Barwon Biotechnology | , | No website Dec 2016-Dec 2018, Sole employee has many other jobs |
| Geno-plex | , | Website gone Feb 2017, no employees found anywhere |
| Phoenix Scientific | , | Not active CA business 2017 - Dec 2024 |
| Sema4 Genomics | , | Renamed GeneDx, Jan 2023 |
| Ortho Regenerative Technologies | , | Renamed ChitogenX, Sep 2022 |
| , | Liquidating, Mar 2025 | |
| EsbaTech | , | Bought by Alcan |
| SpIntellx | , | Renamed PredxBio, Apr 2023 |
| Release Therapeutics | , | Website down Nov 2024 - Jun 2025; fka Maxivax |
| Xcelience | , | Acquired by Capsugel, Jan 2016 |
| Soterius | Princeton, NJ | Outsourced clinical safety, pharmacovigilance, medical affairs, and technology-enabled services |
| Nanalysis Scientific | Calgary, AB | Bench Top NMR |
| DIESSE Diagnostica Senese | Monteriggioni, Italy | Diagnostics |
| , | Relaunched as Anywhere Dx, Jan 2026 | |
| Barinthus Biotherapeutics | Oxford, UK | T cell immunotherapy for Vaccines |
| HiFiBiO Therapeutics | Cambridge, MA | Single cell technologies for drug discovery |
| Clinical Microbiomics | , | Merged into cmbio |
| BioPharm Engineered Systems | Boise, ID | Process Equipment |
| Oruka Therapeutics | Waltham, MA | Biologics for Skin Disease |
| Immune Technology Corp | New York, NY | Virology research products |
| Gradientech | Uppsala, Sweden | Diagnostics, Cell Culture Assays |
| Cellenion | Gothenburg, Sweden | Single Cell Testing |
| Elanix Biotechnologies | , | Website down Sep 2023 - Mar 2024 |
| Virdante Pharmaceuticals | , | Assets acquired by Momenta |
| Human Metabolome Technologies | Yamagata, Japan | Capillary electrophoresis mass spectrometry-based metabolomics technologies |
| Yukin Therapeutics | , | French startup, no website Jun 2019 - May 2023, closed according to Google |
| Catalent | Winchester, KY | Contract Manufacturing |
| Stat One | Morrisvile, NC | eClinical |
| Isogenica | Little Chesterford, UK | Antibody Discovery |
| Nitto Denko Avecia | Cincinnati, OH | Oligonucleotide & Small Molecule CMO |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| Prytime Medical | Boerne, TX | Resuscitative Endovascular Balloon Occlusion of the Aorta |
| , | Liquidated Feb 2025; fka Flash Therapeutics | |
| Lucid Diagnostics | New York, NY | Diagnostics |
| Akebia Therapeutics | Cambridge, MA | Small Molecules |
| BioQ Pharma | San Francisco, CA | Drug infusion systems |
| Resonetics | Quebec, QC | Contract Medical Device Manufacturing & Development |
| Microfluidic Innovations | , | Gone, Founder took job with Oculus VR |
| Interscope | Northbridge, MA | Endoscopic Solutions |
| Fable Therapeutics | Boston, MA | AI Protein Design |
| Cascade Pharmaceuticals | Shanghai, China | Small Molecules, Peptides |
| Progenitec Laboratories | , | Website Gone, Oct 2016, back Dec 2019 but copyright 2012 |
| AOP Orphan Diseases | Prague, Czech Republic | Orphan disease treatments |
| Nanopec | , | Website down Sep 2024 - Feb 2025 |
| Olema Pharmaceuticals | , | Renamed Olema Oncology |
| Unimed Pharma | Bratislava, Slovakia | Ophthalmic Small Molecules |
| Chargepoint Technology | Forked River, NJ | ChargePoint provides transfer solutions to pharmaceutical manufacturing companies |
| |
San Diego, CA | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Pathway Medical | , | Acquired by Bayer, Aug 2011, $125M |
| Evopoint Biosciences | Shanghai, China | Next-generation antibody-drug conjugates (ADCs), and targeted protein degradation (TPD) drugs |
| Sprna | , | Website gone Jan 2020, no info |
| |
Madrid, Spain | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Curium | , | Dissolved, Mar 2015 |
| Patheon | Swindon, UK | Contract Manufacturing and Development |
| Hibiskus Biopharma | , | Acquired by Lodo Therapeutics, Sep 2020 |
| Apotex | Toronto, ON | Small Molecule Generics |
| Orca Bio | Princeton, NJ | Cell Therapy & Manufacturing |
| Qihan Biotech | Hangzhou, China | Genome Editing Platform, Cell/Organ Transplantation Platform |
| Boston Analytical | , | Rebranded as BA Sciences, Jan 2024 |
| , | Bought by Astellas, Feb 2018, $102.5M (milestone-dependent) | |
| DSI InPharmatics | Harleysville, PA | CMC & Regulatory Consultants |
| KYM Biosciences | , | AstraZeneca acquired their ADC for $63M but no website or info, Feb 2023 - Jul 2025 |
| Accurant Biotech | Princeton, NJ | CMC, Bioanalysis, Consulting |
| Hennepin Life Sciences | , | Website gone Dec 2022 - Feb 2023; Residential Address, Nov 2021 |
| BioXpress Therapeutics | Geneva, Switzerland | Biosimilars |
| Orcosa | Ewing, NJ | Orally Disintegrating Tablet |
| Lineage Cell Therapeutics | Carlsbad, CA | Regenerative Medicine |
| Croma-Pharma | Leobendorf, Austria | Aesthetic Medicine |
| Haina Pharmaceutical | , | Acquired by China Sky One, $428k, Apr 2008 |
| PLC Medical Systems | , | Renamed RenalGuard |
| Neumora Therapeutics | Watertown, MA | Precision Medicines for Brain Diseases |
| Delphine Diagnostics | Newark, NJ | Sepsis Diagnostic |
| , | Acquired by Stryker, Oct 2024 | |
| Viant Medical | Fremont, CA | Contract Medical Devices |
| |
Seaport, MA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| INO Therapeutics | , | Merged with Ikaria Feb 2007 |
| , | Website taken over Feb 2026 | |
| Cellceutix | , | Changed named to Innovation Pharmaceuticals, Jun 2017 |
| AstraZeneca | Liverpool, UK | Small Molecules, Vaccines, Biologics |
| H.E.L. Group | London, UK | Parallel and high pressure biotechnology lab equipment |
| Atterocor | , | Renamed Millendo Therapeutics, Jan 2016 |
| Seurat Therapeutics | , | One employee a professor, no news Mar 2021 - Apr 2025 |
| Genopraxis | , | Founder has new job, Jul 2021 |
| Nesch, LLC | , | Website gone Oct 2018 |
| MEDTOX | , | Bought by Labcorp Jul 2012 |
| Astellas | Northbrook, IL | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| NPS Pharmaceuticals | , | Acquired by Shire, Jan 2015, $5.2B |
| Pulsenmore | Omer, Israel | Homecare Ultrasound |
| Fabion Pharmaceuticals | , | Gone 2013? |
| Qbiogene | , | No website. Fisher sells their products |
| Archus Orthopedics | , | Dissolved, Sep 2009 |
| Lee's Pharmaceutical | Hefei, China | Small Molecules |
| Arrowhead Pharmaceuticals | Verona, WI | RNAi |
| BioAnalytix | , | Acquired by Protagen Protein Services, Apr 2019 |
| Odyssey Therapeutics (2) | Boston, MA | Small Molecules, Biologics |
| Promosome | , | Gone |
| Pragma Bio | San Francisco, CA | Microbial-derived small molecules |
| Getinge | Wayne, NJ | Medical Technology |
| Rainier Therapeutics | , | CEO gone, Website down Mar 2020 - Apr 2020; fka BioClin Therapeutics |
| , | Acquired by Bruker, Sep 2020 | |
| Tribun Health | Paris, France | AI Platform company that elevates computational pathology to guide better drug development |
| , | Winding down Jan 2026 | |
| Boyd Consultants | Cheshire, UK | Pharma and Biotech Consulting |
| Hopstem Biotechnology | Hangzhou, China | Cell Therapies |
| ApiJect | Oakland, FL | Single-use injectable delivery system |
| Sucampo Pharmaceuticals | , | Acquired by Mallinckrodt, Feb 2018 |
| Veramed | London, UK | Biostatistics and programming services |
| Apex Molecular | Alderley Edge, UK | Contract Chemistry |
| SpeeDx | Sydney, Australia | In Vitro Diagnostics |
| Dey LP | , | Bought by Mylan 2007 |
| Devonian Health Group | Montmagny, QC | Botanically-sourced Therapeutics |
| ClostraBio | Chicago, IL | Food Allergy Treatments |
| Kobiolabs | Seongnam, Korea | Microbiome Therapeutics |
| PhyNexus | , | Acquired by Biotage, Jan 2019 |
| Xbrane Bioscience | , | Now Xbrane Biopharma |
| AlivaMab Biologics | San Diego, CA | Antibody Discovery Services |
| Cytochroma | , | Acquired by Opko Health |
| Accellacare | Bristol, TN | Clinical Research |
| Pilatus Biosciences | Epalinges, Switzerland | Monoclonal Antibody, Bifunctional Fusion Protein |
| Metabolex | , | Now CymaBay Therapeutics |
| AOP Orphan Diseases | Bromma, Sweden | Orphan disease treatments |
| Partner Therapeutics | Lynnwood, WA | Biologics |
| Richcore Lifesciences | , | Acquired by Laurus Labs, Jan 2021 |
| Sepracor | , | Now Sunovion |
| Bruker | Billerica, MA | Scientific Instruments |
| Viant Medical | Chicopee, MA | Contract Medical Devices |
| Black Diamond Therapeutics | Cambridge, MA | Targeting allosteric mutant oncogenes |
| Meletios Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| Aitiologic | Vienna, Austria | AI-Powered Liquid Biopsy |
| Genpathway | , | Acquired by Active Motif, Nov 2010 |
| Explora Biolabs | , | Acquired by Charles River, Apr 2022, $295M |
| IR2Dx | , | Gone, 2019 |
| Vesigen Therapeutics | , | Assets acquired by Turn Biotechnologies, Mar 2025 |
| Curium Pharma | Paris, France | Nuclear Diagnostics & Medicine |
| CovX Research | , | Bought by Pfizer |
| AltaRex | , | Gone |
| Vakzine Projekt Management | , | Renamed Serum Life Science Europe, Sep 2023 |
| PMI BioPharma Solutions | , | Renamed Aug Bioservices, Jul 2020 |
| Tango Biosciences | Chicago, IL | Reagents via Phage Display |
| Santi Therapeutics | , | Renamed Triana Biomedicines, Feb 2022 |
| Triangle Biotechnology | Chapel Hill, NC | Sample Prep |
| Molecular Designs | Bee Cave, TX | PCR Pathogen Identification |
| Pharmaron | Baltimore, MD | Contract Lab Research, Clinical research |
| Eurodrug Laboratories | The Hague, Netherlands | Generics |
| Anderson and Collins Clinical Research | , | Ceased Operation |
| Clinical Metadata | , | Website down May 2023 - Dec 2023 |
| LFB | Paris, France | Plasma derived drug products |
| IdentifAI Genetics | Tel Aviv, Israel | Prenatal Diagnostics |
| Senorx | , | Acquired by Bard, May 2010, $200M |
| Merida Biosciences | Cambridge, MA | Therapies eliminating pathogenic antibodies |
| Mustang Bio | Worcester, MA | Immunotherapies |
| Sterling Pharma Solutions | Germantown, WI | Contract Development & Manufacturing - APIs |
| Trawsfynydd Therapeutics | , | Merged with Onconova to become Traws Pharma, Apr 2024 |
| Insight Molecular Diagnostics | Nashville, TN | Cancer diagnosis |
| GBM Pharma | , | No website Dec 2019 - May 2023 |
| iCo Therapeutics | , | Acquired by Satellos by Reverse Merger, Aug 2021 |
| Bird Rock Bio | , | Acquired by Skye Bioscience, Aug 2023 |
| Sun BioPharma | , | Renamed Panbela, Dec 2020 |
| Synchron | Brooklyn, NY | Neuroprosthetics |
| Atisama Therapeutics | Melbourne, Australia | RNA-targeting splice-switching oligonucleotides |
| Applied Exomics | , | Renamed Apexomics, Feb 2025 |
| OmegaChem | , | Acquired by NuChem Sciences, Aug 2021 |
| Antisense Pharma | , | Changed name to Isarna Therapeutics, Sep 2013 |
| NeuBase Therapeutics | , | Attempting to dissolve, Jun 2024; Stopped all work Aug 2023; Reverse merged into Ohr Pharmaceutical, Jul 2019 |
| Amphista Therapeutics | Cambridge, UK | Protein Degradation Technologies |
| Amalyte Pharmaceuticals | , | Acquired by Kemin Jun 2009 |
| Novateinbio | Woburn, MA | Proteins and antibodies, assay kits, contract research |
| Achieve Life Sciences | Vancouver, BC | Small Molecules |
| , | Renamed Turing Medical | |
| GlioCart | , | |
| Freudenberg Medical | Würselen, Germany | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Allos Therapeutics | , | Acquired by Spectrum Pharmaceuticals Sep 2012 |
| Nigra | , | Acquired by Vernalis |
| Ranedis Pharmaceuticals | , | Website down Feb 2021 - Sep 2021 |
| Quotient Clinical | , | Renamed Quotient Sciences, Nov 2017 |
| Dualyx | , | Website down Nov 2024 - May 2025 |
| SN Pharma | , | Website down Apr 2023 - Sep 2023 |
| Atheric Pharmaceutical | , | Website taken over and for sale, April-Jun 2018 |
| Lexicon Pharmaceuticals | The Woodlands, TX | Small Molecules, Biologics |
| Chembiotech Laboratories | , | Dormant 2020 - Aug 2024 |
| Studio Biotherapeutics | , | No business update since Sep 2017 as of Nov 2019; Marked as closed on Google |
| PhotoniCare | Durham, NC | Optical Coherence Tomography for Ear Examination |
| Cascadia Global Research | , | Website down Oct 2018, seems defunct |
| Indoco Remedies | Mumbai, India | Contract Small Molecules |
| Fresenius Kabi | Lake Zurich, IL | Infusion Therapy |
| Siemens Healthineers | Tarrytown, NY | Medical imaging, laboratory diagnostics, and healthcare information technology |
| Peninsula Pharmaceuticals | , | Acquired by Ortho-McNeil, Apr 2005 |
| Bipar Sciences | , | Bought by Sanofi-Aventis, Apr 2009, $500M |
| Innovate Biopharmaceuticals | , | Renamed 9 Meters Biopharma after merging with RDD Pharma, Apr 2020 |
| Collaborative Drug Discovery | Burlingame, CA | Biological & Chemical Database |
| Nova Satra Dx | , | Merged with Inex Innovations Exchange, Aug 2019 to become Inex Innovate |
| Araceli Biosciences | Tigard, OR | Instruments for tissue and cell-based biomarker discovery, drug discovery and drug development |
| Bone Therapeutics | , | Renamed Biosenic, Oct 2022 |
| NuVera Medical | , | Acquired by Biosense Websiter, Sep 2021 |
| Charles River Laboratories | Morrisville, NC | Research Animal Models and Preclinical Research |
| Apollomics | Foster City, CA | Cancer medicines |
| Aceragen | , | Bankrupt, Jul 2023, Liquidating |
| Pfizer | Clondalkin, Ireland | Biologics |
| Convergen | , | |
| Confab | St-Hubert, QC | Contract Manufacturing & Services |
| Genaera | , | Dissolved |
| CorMedix | Berkeley Heights, NJ | Small Molecules |
| Integra LifeSciences | Milan, Italy | Medical Devices |
| Chanelle Pharma | Loughrea Co Galway, Ireland | Generics |
| Pinnacle Pharmaceuticals | , | Acquired by New River Pharmaceuticals, 2011 |
| Bellus Medical | , | Renamed Crown Aesthetics |
| Excel BioPharm | , | Website Down Dec 2022 - Mar 2023 |
| Century Therapeutics | Philadelphia, PA | iPSC Therapy platform |
| Arris Pharmaceuticals | , | Changed name to Axys Pharmaceuticals |
| Sekisui Diagnostics | San Diego, CA | Diagnostics |
| Phyton Biotech | Delta, BC | Plant Cell Culture |
| Marathon Pharmaceuticals | , | Sold lone asset to PTC Therapeutics, Apr 2017 |
| RegeneCore Biotech | Nanjing, China | Nanobody Screening Technology |
| Xellia Pharmaceuticals | , | Acquired by Novo, May 2024 |
| Bina Technologies | , | Acquired by Roche, Dec 2014 |
| Third Pole Therapeutics | Waltham, MA | Inhaled NO Delivery System |
| Alta Biomaterials | , | Renamed Alta Biomed, Apr 2025 |
| Alcon | Irvine, CA | Eye-Care Products |
| , | Website down May 2025 - Nov 2025 | |
| Vaccitech | , | Renamed Barinthus Biotherapeutics, Nov 2023 |
| Luminary Genetics | Santa Clara, CA | Genetic Testing |
| BOA Biomedical | , | Website down Jun 2024 - Nov 2024 |
| Encycle Therapeutics | , | Acquired by Zealand Pharma, Oct 2019, up to $80M |
| Miami Cardiovascular Innovations | , | Gone, site still up |
| Mondobiotech | , | Changed name to THERAmetrics, Jun 2013 |
| Peritia | Morrisville, NC | Consulting |
| Mitokine Bioscience | , | Seems to be a research library now |
| Bonenta | , | Website gone |
| WntResearch | , | Shell acquired by Opsy |
| Pierre Fabre | Soual, France | Oncology, derm / cosmetics |
| Alia Therapeutics | Trento, Italy | Targeted Gene Editing |
| Twist Bioscience | Carlsbad, CA | Synthetic DNA, genes and libraries |
| Sunrise Pharmaceuticals | Rahway, NJ | Contract Everything |
| Dascena | , | Acquired by CirrusDx, Aug 2022 |
| ImmuneXcite | , | Closed Oct 2017 |
| Pregenen | , | Bought by bluebird bio Jun 2014 |
| BioShin Pharmaceuticals | , | Website down Dec 2022 - Apr 2023 |
| Redona Therapeutics | Watertown, MA | Small Molecules to Target ncRNA Biology |
| Varian Bio | , | Acquired by Biodexa, May 2023 |
| CytoImmune Therapeutics | Duarte, CA | Cancer Immunotherapy |
| Agappe Diagnostics | Cham, Switzerland | Analyzers, Reagents |
| SMC | Cambridge, UK | Small batch sterile filling for clinical trials |
| Alteris Therapeutics | , | Bought by Celldex Oct 2005, $1.5M plus stock/milestones |
| Baliopharm GmbH | , | Bought by Alvotech, May 2016 |
| BioSyent | Mississauga, ON | Acquisition & Marketing of Approved Products |
| Creative Antibiotics | , | Filed for bankruptcy, Jun 2013 |
| Binx Health | Cambridge, MA | Medical, Consumer Diagnostics |
| Axis Clinicals | Hyderabad, India | Clinical Trials |
| StemXgend | , | Website down Dec 2019, never even registered as a business in CA |
| Immagene | , | Renamed Flindr Therapeutics |
| ImThera Medical | , | Acquired by LivaNova, Dec 2017 |
| Zenopharm | , | Website down Aug 2024 - Jan 2025 |
| Massive Bio | Boca Raton, FL | Oncology Clinical Trials |
| Aurigene Oncology | Kuala Lumpur, Malaysia | Drug discovery |
| Obetherapy Biotechnology | , | Website gone Jan 2020 |
| Alzinova | Mölndal, Sweden | Alzheimer's Vaccine, Monoclonal Antibody Technology |
| RVAC Medicines | , | Website down, Jan 2024 - Jul 2024 |
| Synergy Health | , | Acquired by Steris, Nov 2015 |
| SphynKx Therapeutics | , | Gone |
| Syngle Therapeutics | Randstad, Netherlands | Antibodies for neuro indications |
| Evergen | Alachua, FL | Comprehensive portfolio of allograft and xenograft biomaterials |
| Genera Medix | , | Apparently sold all products |
| Folia Biotech | , | Website Gone May 2018 |
| , | Acquired by Uniphar | |
| Apnex Medical | , | Shut down, Aug 2013 |
| Innocrin Pharmaceuticals | , | Gone post 2018 |
| , | Acquired by Novartis, Apr 2025, $3.1B | |
| Alivio Therapeutics | , | Fully absorbed into PureTech, Jun 2021 |
| HUMAN Diagnostics | Wiesbaden, Germany | Lab Diagnostic Products |
| BioSTAR West | , | Merged with Hawaii Chitopure and became Synedgen 2009 |
| Bostal Pharma | Edison, NJ | Drug delivery technologies, Generics |
| AdhexPharma | Chenôve, France | Drug Delivery Technology |
| JSS Medical Research | Bogotá, Colombia | Clinical Research & Consulting |
| AccuPulse | Jiangsu, China | Pulse Field Ablation System, Cardiac Mapping System |
| SommaTech Consulting | , | Website down Apr 2024 - Aug 2024 |
| yuFlu | , | No website, no info Feb 2021 |
| Biofrontera | Leverkusen, Germany | Dermatology Treatments |
| Auxulin Pharmaceuticals | , | Pivoted to supplements |
| Nucollagen | , | Website gone Dec 2021; Never registered as business in CA |
| Rhone-Poulenc Rorer | , | Merged with Hoechst AGto form Aventis, 1999 |
| Trianni | , | Acquired by AbCellera, Nov 2020, $90M |
| Plexxikon | , | Acquired by Daiichi Sankyo, Feb 2011 |
| Synbio Technologies | Monmouth Junction, NJ | Synthetic biology solutions, custom DNA synthesis, gene editing, protein expression, antibody services |
| QRD Pharma | Warrington, PA | Bioanalytical, Chiral Analysis, and DMPK services |
| Dover Lifesciences | , | Website down Jun 2020 - Dec 2020; Residential Address Jul 2019; One page website, Dec 2018 |
| Pace | Oakdale, MN | Analytical Testing, CDMO |
| Kreatech Diagnostics | , | Acquired by Leica Biosystems, Jul 2013 |
| Zymo Research | Tustin, CA | Epigenetics, DNA, RNA research products |
| Neuro Bio | Oxford, UK | T14 Blocker |
| AbTherx | Mountain View, CA | Therapeutic Antibody Discovery |
| Ruga | , | Changed name to Aravive Biologics, Nov 2016 |
| AYOXXA | , | Website down Feb 2023 - Jul 2023 |
| Myi Diagnostics & Discovery | , | Gone 2018 |
| miR Scientific | , | Renamed miRNA Scientific |
| Lattice Biologics | , | Seems gone as of mid-2021; Formerly International Biologics, formerly in Arizona |
| Apoplex Medical Technologies | Pirmasens, Germany | Automated Afib Detection |
| |
Irvine, CA | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| , | Website down Jan 2026 - May 2026 | |
| Par Pharmaceutical | , | Acquired by Endo Pharmaceuticals, Sep 2015, $8.05B |
| Barr Laboratories | , | Changed to Barr Pharmaceuticals |
| BiOrion Technologies | , | Gone Sep 2023. Assets moved to Cortalix |
| Mosaic Biomedicals | , | Website down Jul 2021 - Jan 2022 |
| Riboscience | Sunnyvale, CA | Ribose-Based Therapies |
| BBB Therapeutics | , | Bankrupt 2015 |
| Plexcera Therapeutics | , | May have spun operations into Enzyvant Sciences, Jul 2016 |
| Daré Bioscience | San Diego, CA | Women's Health |
| NovaBioAssays | Woburn, MA | Mass Spec Services |
| InterVenn BioSciences | South SF, CA | Cancer Diagnostic |
| Canvax | , | Website down Aug 2022 - Jan 2023 |
| Mezomax | , | Website down Mar 2023 - Dec 2023 |
| Blackrock Microsystems | , | Renamed Blackrock Neurotech, Apr 2022 |
| Adamis Pharmaceuticals | , | Merged with DMK Pharmaceutical, May 2023, took name |
| CerCell | Herlev, Denmark | Single-Use Bioreactors |
| StaphOff Biotech | , | Shut down 2017 |
| Epic Sciences | , | Shut down May 2025 |
| Parat Systems | , | Acquired by BD, Jul 2022 |
| Empiriko | Newton, MA | Drug metabolite creation for drug discovery |
| Hybrigenics | , | Renamed ATON |
| Stallergenes Greer | Baar, Switzerland | Allergen Desensitization |
| NGM Biopharmaceuticals | South SF, CA | Type 2 Diabetes |
| Pfizer | Rocky Mount, NC | Sterile Injectables |
| Macrophage Pharma | , | Bankruptcy, Feb 2022 |
| Stago | Clarkston, GA | Diagnostics |
| Afmedica | , | Acquired by Angiotech, Sep 2005 |
| GSK | Stevenage, UK | Small Molecules, Vaccines, Biologics |
| VIDA Diagnostics | Coralville, IA | Lung Diagnostic Technology |
| Vyrsa Technologies | , | Acquired by Nevro, Dec 2023, $40M + $35M milestones |
| SoloHill Engineering | , | Acquired by Pall, Mar 2014 |
| Integrated Micro-Chromatography Systems | Irmo, SC | Recombinant enzymes and proteins, tip-based chromatography, sample preparation, and laboratory automation |
| Nanox | Petach Tikva, Israel | Digital X-Ray |
| Pegasus Biologics | , | Assets acquired by Synovis Life Technologies, Jul 2009 |
| MethylGene | , | Bought by Mirati Therapeutics Jun 2013 |
| Ocean Genomics | , | Renamed Ellumigen, Jun 2025 |
| Spencer Pharmaceuticals | , | Gone, taken down by SEC for scammy behavior |
| TesoRx | Menlo Park, CA | Formulations platforms |
| Vietstar Biomedical Research | Hanoi, Vietnam | Clinical Research |
| Wickham Micro | Hampshire, UK | Specialized pharmaceutical and medical device testing in the fields of microbiology |
| Erimos Pharmaceuticals | , | All employees have moved on. Website not changed since 2007. |
| Gener8 | Wilmington, MA | Medical Devices Prototyping, Engineering & Design; Biotech Consumables |
| Dorian Therapeutics | , | Acquired by Altos Labs, May 2025 |
| Arthroventions | , | Website down Feb 2025 - Jul 2025 |
| CTF MEG Neuro Innovations | Coquitlam, BC | Magnetoencephalography |
| |
Hayward, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Cellular Technology Limited | Shaker Heights, OH | Preserved Cells, Imaging Machinery, Reagents, etc. |
| Prosensa | , | Acquired by BioMarin, Nov 2014, $680M+milestones |
| Apcer Life Sciences | Ahmedabad , India | Consultants |
| Engage Bio | San Carlos, CA | Tethosome Gene Therapy |
| FORMA Therapeutics | , | Acquired by Novo Nordisk, Oct 2022, $1.1B |
| SCOLR Pharma | , | Closed Mar 2013 |
| |
Beograd, Serbia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Pivotal BioSciences | , | Shut down late 2018 |
| CryoTherapeutics | Loncin, Belgium | Cryotherapy Catheter Device for Coronary Artery Disease |
| GW Pharmaceuticals | , | Bought by Jazz Pharmaceuticals, May 2021 |
| Calixa Therapeutics | , | Acquired by Cubist, Dec 2009, $92.5M + $310 milestones |
| Matterhorn Biosciences | , | Website down Apr 2024 - Sep 2024 |
| MDxHealth | Irvine, CA | Molecular Diagnostics |
| Insightec | Miami, FL | Thermal Ablation via Ultrasound |
| Semprus Biosciences | , | Acquired by Teleflex Jun 2012 |
| Reven Pharmaceuticals | Westminster, CO | IV drug delivery platform |
| Progenity | , | Renamed Biora Therapeutics, Apr 2022 |
| Asarina Pharma | , | Winding down Jul 2024 |
| Venatorx Pharmaceuticals | Malvern, PA | Antibacterials |
| Nuventra Pharma Sciences | , | Now Allucent |
| Firebird Biomolecular Sciences | Alachua, FL | Lab Reagents |
| Lyndra Therapeutics | , | Winding down Mar 2025 |
| Nanology Labs | , | Renamed QurCan Therapeutics |
| Impact Biomedicines | , | Bought by Celgene, Jan 2018, up to $7B |
| Proacta | , | Gone 2014 |
| Opentrons | New York, NY | Lab Automation Robots |
| Atec Spine | Carlsbad, CA | Products for Spine Surgery |
| Sun Biomedical | , | Acquired Dimerix, Jul 2015, took name |
| Eli Lilly | Sesto Fiorentino, Italy | Small Molecules, Biologics |
| Biotix | San Diego, CA | Lab Consumables |
| Apton Biosystems | , | Acquired by Pacific Biosciences, Sep 2023, $85M + $25M milestones |
| Gwynant Therapeutics | , | Not registered business in UK; No website Sep 2021 - Jul 2024 |
| Biopticon | Princeton, NJ | Tumor Imaging |
| Phenix Research Products | , | Acquired by Thomas Scientific |
| Viant Medical | Brimfield, MA | Contract Medical Devices |
| Medtronic | Mounds View, MN | Medical Devices |
| |
Hamme, Belgium | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Cyto360 | , | Website gone Aug 2018 |
| Lifecode Health | , | Assets Acquired by MedGenome, Feb 2016 |
| Koye Pharmaceuticals | Mumbai, India | Small Molecules, Biologics |
| Imvaria | Berkeley, CA | Digital Biomarker Platform |
| Stitch Bio | , | No website, no info Sep 2020 - May 2023, seems like solo person |
| AsymBio | Jinshan, China | Biologics CDMO |
| NeuroBioPharm | , | Almost no info out there. Spinoff of Neptune |
| 3dbiosurfaces Technologies | , | Website gone Sep 2022 |
| Potenza Therapeutics | , | Bought by Astellas, Dec 2018 |
| , | Renamed Nectero Therapeutics, Feb 2026 | |
| Tactic Pharma | , | Website gone, Apr 2018 |
| TRImaran Pharma | , | Website gone Oct 2018; Virtual company |
| BC Platforms | Zurich, Switzerland | Genomic Data Management |
| Nanobiosym | Cambridge, MA | Nanobiotech |
| Intelivation | Plymouth Meeting, PA | Orthopedic Implants |
| Biocytogen | Beijing, China | CRISPR genome editing, preclinical services |
| Adagene | Suzhou, China | Antibody discovery & engineering |
| Conforma Therapeutics | , | Acquired by Biogen Idec, May 2006, $150M stock + $00M Milestones |
| NeuMedics | , | Website taken over by massager sales |
| Accelsiors | Budapest, Hungary | Clinical Research |
| Ironwood Pharmaceuticals | Boston, MA | Small Molecules |
| Annovation Biopharma | , | Acquired by The Medicines Company, Feb 2015 |
| Theravance | , | Changed name to Innoviva, Jan 2016 |
| Evonik Industries | Birmingham, AL | Biomaterials |
| Interpace Diagnostics | , | Renamed Interpace Biosciences, Nov 2019 |
| REV Clinical | Bakersfield, CA | Clinical Trials |
| StudyKIK | , | Acquired by Syneos Health, Sep 2021 |
| Pierre Fabre | Gaillac, France | Oncology, derm / cosmetics |
| Biotechnical Services | , | Shut down Apr 2019 |
| GenSpera | , | Renamed Inspyr, Aug 2016 |
| Photocure | Princeton, NJ | Diagnostics & Small Molecules |
| Cellcyte Genetics | , | SEC troubles in 2008ish, gone |
| Gore Medical | Flagstaff, AZ | Medical & Surgical Devices |
| Miraca Life Sciences | , | Renamed Inform Diagnostics, Jan 2018 |
| Charles River Laboratories | Willimantic, CT | Research Animal Models and Preclinical Research |
| CombImmune | , | Website Gone Jul 2015 |
| Activartis | , | Seems to have been folded back into AOP Orphan after previously being spun out. |
| Surgenex | Scottsdale, AZ | Cellular & Tissue-Based Products |
| Precision Nanosystems | , | Acquired by Cytiva, Apr 2024 |
| JSC Pharmstandard | Moscow, Russia | 300+ pharmaceutical products (small molecule?) for various areas |
| |
Aix-en-Provence, France | Neuroservices-Alliance is a global Contract Research Organization (CRO) specializing in preclinical Central Nervous System (CNS) and pain drug discovery. We partner with pharmaceutical and biotech companies to accelerate research by providing translational functional data, mechanism of action (MOA) studies, and target engagement validation. |
| Nihon Kohden | Irvine, CA | Medical Electronic Equipment |
| Glycomine | San Carlos, CA | Glycosylation corrective therapy |
| ACLIRES Bangkok | , | Website gone Jan 2025 - Feb 2025 |
| VWR | Radnor, PA | Lab Products & Chemicals |
| Qualitest Pharmaceuticals | , | Became part of Endo, 2010 |
| BioHelix | , | Acquired by Quidel, $10+milestones, May 2013 |
| Molecular Designs | Birmingham, AL | PCR Pathogen Identification |
| PharmaLex | Sofia, Bulgaria | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| CoreLab Partners | , | Bought by JLL then merged with Bioclinica, 2013 |
| E-MSion | , | Acquired by Agilent, Mar 2023 |
| Quench Bio | , | Wound down Mar 2021 |
| Bio Usawa Biotechnology | ZZ, Rwanda | Biosimilars |
| ActinoDrug Pharmaceuticals | , | Bankrupt |
| Endogena Therapeutics | San Francisco, CA | Regenerative Medicine |
| Perosphere Pharmaceuticals | , | Acquired by AMAG Pharmaceuticals, Jan 2019 |
| Jiangsu Pacific Meinuoke Biopharmaceuticals | Changzhou, China | Monoclonal Antibodies, CAR T |
| Molecular Diagnostic Services | , | Dissolved, Apr 2015 |
| LENZ Therapeutics | Del Mar, CA | Ophthalmology Treatments |
| , | Portfolio acquired by Gedeon Richter, Mar 2026 | |
| HeartWare | , | Bought by Medtronic, Aug 2016, $1.1B |
| Imstem Biotechnology | , | Website gone May 2021 |
| PolyPeptide Group | Strasbourg, France | Polypeptide Manufacturing |
| Alion Pharmaceuticals | , | Shut down Dec 2024 |
| Vir Biotechnology | San Francisco, CA | Infectious disease therapies |
| TYRX | , | Acquired by Medtronic, Jan 2014, $160M |
| Scinai Immunotherapeutics | Jerusalem, Israel | Universal Influenza Vaccine, Adjuvants |
| Oxehealth | , | Pivoted to mental health platform |
| Eximo Medical | , | Acquired by AngioDynamics, Oct 2019, $46M + $20M milestones |
| Biovail | , | Merged with Valeant |
| GentiBio | Seattle, WA | Engineered regulatory T cells |
| Neuprozyme Therapeutics | , | Website down Dec 2020 - May 2021 |
| Abcepta | San Diego, CA | Biotechnology Antibodies |
| Halo Biosciences | Palo Alto, CA | Small Molecules |
| Polyganics | , | Acquired by Collagen Matrix, Oct 2022 |
| Simplify Medical | , | Acquired by NuVasive, Feb 2021, $150M |
| Sygnature Discovery | Nottingham, UK | Drug Discovery Contract Research |
| Amplion | , | Acquired by Science & Medicine Group, Sep 2022 |
| Steroglass | Perugia, Italy | Scientific Instrumentation |
| Inimex Pharmaceuticals | , | Website taken over, company presumed gone |
| , | Shut down Jul 2014 | |
| Maccine | , | Gone |
| Medtronic | Eatontown, NJ | Implants & Grafts |
| Prochon Biotech | , | Acquired by Histogenics |
| Sangamo Therapeutics | Richmond, CA | Biologics |
| Neural Analytics | , | Renamed NovaSignal |
| Applied Medical Technology | Brecksville, OH | Medical Devices |
| MoonLake Immunotherapeutics | Zug, Switzerland | Tri-Specific Nanobody |
| Avadel Specialty Pharmaceuticals | , | Filed chapter 11, Feb 2019, bought by Roivant Apr 2019 |
| IgE Pharmaceuticals | , | Website gone Sep 2020; Not registered as CA business, Mar 2020 |
| ReVENT Medical | , | Website Gone, Oct 2017 - Dec 2017 |
| Xip Diagnostics | , | Website down Jan 2022 - Jul 2022 |
| TaliaPharm | , | Website gone, Jan 2018 |
| Avia Pharma | Stockholm, Sweden | In-licensing, Acquisitions |
| Metastatix | , | No info Dec 2019; Financed in 2007 |
| Third Coast Therapeutics | , | Website down Jan 2021 - Feb 2022, CEO left Dec 2020, no real employees |
| EMPECS Medical Device | Seongnam, Korea | Diagnostics and medical devices |
| AVEO Pharmaceuticals | , | Now go by AVEO Oncology |
| Nucleus Biologics | San Diego, CA | Cell culture products |
| Solinas Medical | , | Website down Mar 2025 - Aug 2025 |
| Metrodora Therapeutics | , | No website, founded 2009, no real employees on LI, website is parked as of Nov 2017 |
| Mito BioPharm | , | Professor side project, old and no news 2018-2024 |
| Nexeon MedSystems | , | Website gone Jun 2020, stock close to worthless |
| DaVinci Biosciences | , | Closed down 2017 after being convicted of Federal & CA state violations |
| Prime Medicine | Cambridge, MA | Gene Editing Technology |
| PrinterPrezz | , | Renamed Zeda, Mar 2023 |
| Regenexx | Des Moines, IA | Medical Stem Cell Procedures |
| Revolution Biomanufacturing | Canton, MA | mRNA, lipid nanoparticle CDMO |
| PriZm Therapeutics | Chandler, AZ | Therapies for ultra-rare pediatric orphan diseases |
| Signant Health | Horsham, PA | eClinical Solutions |
| Foxx Life Sciences | Salem, NH | Lab bottles, bags, strainers, filters |
| Quantex Laboratories | , | Doesn't seem active, Jul 2018 |
| Baseimmune | London, UK | Cross-Protective Vaccine3s |
| AnaBioTec | , | Now Anacura |
| Chembridge Corporation | San Diego, CA | Screening Libraries |
| Mynosys Cellular Devices | , | Renamed Centricity Vision, Jun 2020 |
| Pelican Therapeutics | , | Bought by Heat Biologics, Mar 2017 |
| Rebiotix | , | Acquired by Ferring, Apr 2018 |
| LGC Biosearch Technologies | Steinach, Germany | Reagents, Probes, Oligonucleotides |
| ETAP-lab | Vandoeuvre-lès-Nancy, France | Preclinical CRO |
| McGuff Pharmaceuticals | Santa Ana, CA | Contract Manufacturing |
| Biosynex | Illkirch-Graffenstaden, France | Rapid Diagnostic Tests |
| Napo Pharmaceuticals | , | Merged with Jaguar Animal Health, Jul 2017. |
| Chestnut Pharmaceuticals | , | Gone pre Jun 2019 |
| Velomedix | , | Shut down 2014 |
| Seneca Biopharmaceuticals | , | Merged with Leading BioSciences to become Palisade Bio, Apr 2021 |
| Chemveda Life Sciences | Bridgewater, MA | Drug Discovery & development Services |
| Brainlab | Munich, Germany | Software & Hardware for Surgical Use |
| Nteryx | , | Changed name to Ardelyx |
| Inteligex | Toronto, ON | Stem cell and drug-based therapies for traumatic spinal cord injury |
| Karessa Pharma | , | Website down Apr 2021 - Sep 2021 |
| Matrisome Bio | Cambridge, MA | Transforming therapy through the extracellular matrix |
| Biofabri | Pontevedra, Spain | Vaccines & Immunotherapy |
| , | Website down Jul 2025 - Oct 2025 | |
| RedShift BioAnalytics | Boxborough, MA | Analytical instrumentation for life science research |
| Etana Biotechnologies | Jakarta, Indonesia | Biosimilars |
| Concept Medical | Tampa, FL | Coated Balloon Catheter, Drug-eluting stent with balloon |
| eFFECTOR Therapeutics | , | Winding down Jun 2024 |
| GeneProt | , | Shut down Apr 2005 |
| Junevity | San Francisco, CA | Long-lasting siRNA Therapies |
| Redoxis | Lund, Sweden | Drug development CRO |
| BioWa | , | Part of Kyowa Kirin Group |
| Burst Biologics | , | Website down Oct 2022 - Mar 2023 |
| CelLBxHealth | Plymouth Meeting, PA | Liquid Biopsy |
| RotaChrom Technologies | Kecskemet, Hungary | Centrifugal Partition Chromatography manufacturer and method developer |
| CIS Pharma | Bubendorf, Switzerland | Polymer-drug Conjugates, Ophthalmic Devices |
| Clinqure | Virtual, | Clinical, Quality & Regulatory Services |
| Tangen Biosciences | , | Website down Dec 2023 - May 2024 |
| Teva | Toronto, ON | Small Molecules |
| Altiris Therapeutics | , | Presumed Gone |
| SWITCH Biotech | , | Gone, 2020 |
| Pulmo Biotech | , | Delisted 2014, website gone for a while, still copyright 2011 as of Dec 2019 |
| Cerevel Therapeutics | , | Acquired by AbbVie, Aug 2024, $8.7B; Went public via SPACquisition Oct 2020 |
| Cogenics | , | Now Beckman Coulter Genomics |
| Gilead | Oceanside, CA | Small Molecules |
| Zavante Therapeutics | , | Bought by Nabriva Therapeutics, Aug 2018, 8.2M shares |
| Radial Therapeutics | , | Gone. President had no scientific background. 'Founder' was a freshmen in college |
| MBL International | , | Acquired by JSR Life Sciences, Mar 2021 |
| PaxMed | Carlsbad, CA | Medical Device Regulatory Consulting |
| Neurotech Pharmaceuticals | Cumberland, RI | Encapsulated Cell Therapy |
| Confluence Discovery Technologies | St. Louis, MO | Drug Discovery CRO |
| TherOx | , | Acquired by Zoll, Jun 2019 |
| Neoantigenics | , | Website gone Sep 2017 |
| PrimeFour Therapeutics | , | Assets Acquired by Transposon Therapeutics, Nov 2024 |
| Lewis and Clark Pharmaceuticals | , | Website back Mar 2019 - possibly resurrected as a rebranding of parent Inspyr; Merged into Inspyr Therapeutics, Sep 2017 |
| Gossamer Bio | San Diego, CA | Small Molecules |
| Goodwin Biotechnology | , | Renamed GBI Biomanufacturing |
| Biosplice Therapeutics | San Diego, CA | Small Molecules Acting on Stem Cells |
| Complement Pharma | , | Acquired by Graviton Bioscience, Dec 2022 |
| Knudra Transgenics | , | Merged with NemaMetrix, Nov 2017 |
| , | Website down Oct 2025 - Feb 2026 | |
| mibe Arzneimittel | Brehna, Germany | Generics |
| EnBiome Therapeutics | , | Website down, Dec 2019 - Mar 2020; Not registered in MA Dec 2019 |
| NBE-Therapeutics | Basel, Switzerland | Next Gen ADCs |
| IncellDx | , | Renamed HealthBio AI |
| AbelZeta Pharma | Shanghai, China | Cell Therapy |
| Kar Bioanalytical | , | Seem gone |
| Dewpoint Therapeutics | Boston, MA | Biomolecular Condensates |
| Lupin | Coral Springs, FL | Generics |
| New Haven Pharmaceuticals | , | Presumed Gone, 2016 |
| CustomArray | , | Acquired by GenScript, Dec 2017 |
| Aegerion Pharmaceuticals | , | Aegerion operated as subsidiary of Novelion Therapeutics until declaring bankruptcy and being acquired by Amryt Pharma, May 2019; Merged with QLT, Nov 2016 |
| Hovione | Baar, Switzerland | Contract Manufacturing |
| Jiuzhou Pharma | Hangzhou, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Allergy Laboratories | , | Likely acquired by ALK-Abello, Dec 2016 |
| KBP BioSciences | , | Website down Apr 2025; selling lead product Oct 2023 |
| BDR Pharmaceuticals | Mumbai, India | APIs, New Age Formulations |
| Vaccinogen | , | Stock worthless. Likely shell company. |
| Facile Therapeutics | , | Shut down Dec 2021 |
| Almac | Macclesfield, UK | Pharmaceutical Services |
| Cellenion | Berlin, Germany | Single Cell Testing |
| YSL Bioprocess Development | , | Renamed AimPlex Biosciences |
| Adrestia Therapeutics | , | Acquired by Insmed, Jul 2023 |
| iVis Technologies | Taranto, Italy | Corneal Surgery Device |
| Sermes | Madrid, Spain | Full Service CRO |
| Abacus Bioscience | Seattle, WA | Anti-CD180 Monoclonal Antibodies |
| Notify Therapeutics | Copenhagen, Denmark | Activation of dormant egg follicles |
| Aronora | Portland, OR | Recombinant monoclonal antibodies and enzymes |
| , | Seems renamed to Lusis Biosciences | |
| Neurotargeting Systems | , | Website Gone, Nov 2016 |
| Ascensia Diabetes Care | Basel, Switzerland | Diabetes Devices |
| Arcensus | Rostock, Germany | Genetic Diagnostics |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Vion Pharmaceuticals | , | Bankrupt, defunct 2010 |
| HistoIndex | Singapore, Singapore | Digital Pathology |
| Lee's Pharmaceutical | Hong Kong, China | Small Molecules |
| WDPrx - Woodfield Pharmaceutical | , | Acquired by Reliable HealthCare Logistics |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
| Samsara Vision | Far Hills, NJ | Ophthalmic devices |
| Advanced Biotechnologies | , | Shut Down Nov 2023 |
| Milestone Scientific | Roseland, NJ | Epidural Placement Technology |
| Velosal Medical | , | Website down Dec 2020 - May 2021; Business revoked in NC |
| Orchid Orthopedic Solutions | Holt, MI | Contract Medical Device Work |
| Celther Polska | , | Website down Jan 2021 - May 2021 |
| Qiagen | Hilden, Germany | Molecular Diagnostics, Assays, Reagents, Antibodies |
| Eurofins Advinus | Bangalore, India | Drug Discovery |
| , | Renamed Kainova Therapeutics, Jan 2026 | |
| Laboratorios Rubio | Barcelona, Spain | Diagnostics, Small Molecules |
| ProRelix Research | Karve Nagar, India | Clinical Research Organization with Global Service Capability |
| , | No news 2020 - Apr 2026 | |
| inHEART | Pessac, France | AI-enabled Digital Heart Twin |
| SilaGene | , | Gone |
| Envisia Therapeutics | , | Technology purchase by Aerie, Oct 2017 |
| Ocugen | Malvern, PA | Sight-threatening Diseases |
| Hauser Pharmaceutical Services | , | Acquired by Cedarburg |
| CardioCell | , | Founder gone 2021; No business filings from Oct 2017 through Dec 2020; Spun out of Stemedica |
| Therapeia | , | Program Acquired by Telix, Jan 2017 |
| ReproCELL | Glasgow, UK | 3D Cell Culture |
| CELLDI | , | Website down Apr 2024 - Sep 2024 |
| Kallyope | New York, NY | Gut-brain axis focus |
| , | Gone Sep 2025 | |
| Nohla Therapeutics | , | Website down Feb 2020 - Oct 2020 |
| Encore Vision | , | Bought by Novartis, Dec 2016 |
| Kurin | San Diego, CA | Blood Collection Technology |
| US Medical Innovations | Takoma Park, MD | Plasma Surgery |
| ImaBiotech | , | Renamed Aliri, May 2023 |
| Immunomic Therapeutics | Rockville, MD | Vaccines (Lysosomal Associated Membrane Protein) |
| Digene | , | Merged with Qiagen |
| Zyber Pharmaceuticals | , | Reverse Merged into Pernix Therapeutics, Mar 2010 |
| Greatbatch | , | Changed name to Integer, Jul 2016 |
| MilliporeSigma | St. Louis, MO | Expression systems, ADCs |
| , | Acquired by Jazz Pharmaceuticals, Apr 2025 | |
| Bentley Pharmaceuticals | , | Bought by Teva, Mar 2008, $360M |
| AllinkBio | Shanghai, China | ADS, Bispecific Antibodies |
| Chaperone Therapeutics | , | Gone 2019 |
| LifeQual Pharmaceuticals | , | Website Gone |
| Neurona Therapeutics | South SF, CA | Neuronal stem-cell therapies |
| Confluent Medical Technologies | Laguna Niguel, CA | Contract Medical Devices, Nitinol, Catheters, Textiles |
| Wexler Surgical | Houston , TX | Surgical Instrumentation |
| Bionsight | Seoul, Korea | Database For Research |
| MCS Clinical Trials | , | Website Down Jul 2014, Presumed defunct |
| Symeres | Groningen, Netherlands | Drug Discovery Contract Research |
| Tegra Medical | La Aurora de Heredia, Costa Rica | Contract Medical Device Manufacturer |
| B-Temia | St-Augustin-de-Desmaures, QC | Walking-Assist Exoskeleton |
| Meribel Pharma Group | Orleans, France | Contract Manufacturing |
| CloudCath | San Francisco, CA | Remote Catheter Monitoring Platform |
| Co-Formulate | , | Acquired by Quotient Clinical, Feb 2017 |
| Vet-Stem | , | Changed name to VetStem Biopharma, Apr 2015 |
| , | No news 2021 - Jan 2026 | |
| TriNetX | Cambridge, MA | Clinical Data Management Software |
| Lepu Biopharma | Shanghai, China | ADCs, oncolytic viruses, immunotherapies |
| Med Discovery | , | Website under construction May 2020 - Mar 2021 |
| Ariadne Diagnostics | , | Website gone Apr 2019 |
| EDP Biotech | , | Merged into New Day Diagnostics, Jul 2023 |
| Atsena Therapeutics | Durham, NC | Gene Therapy |
| Indiana Lysis Technologies | , | No website Oct 2019 - Dec 2023 |
| Delonix Bioworks | , | Website down Jan 2022 - Jul 2022 |
| Kiromic BioPharma | , | Bankrupt, May 2025; fka Kiromic |
| , | Website down Dec 2025 - Apr 2026 | |
| , | Acquired by nonprofit, Jul 2025; Bankruptcy, Mar 2025 | |
| PCI Pharma Services | Meath, Ireland | Contract Manufacturing, Services |
| Julius Clinical | Zeist, Netherlands | Clinical Research |
| Preventice Solutions | , | Acquired by Boston Scientific, Jan 2021, $925M + $300M milestones |
| Duke Empirical | Morgan Hill, CA | Device Manufacturing & Design |
| Zumutor Biologics | Bangalore, India | Biologics |
| Aarden Pharmaceuticals | , | Confirmed gone by co-founder |
| Accurant Biotech | Shanghai, China | CMC, Bioanalysis, Consulting |
| Valpharma | Pennabilli, Italy | Generics, Contract Manufacturing |
| Advansta | San Jose, CA | Protein characterization products |
| GliaGen | , | Renamed CaCy Therapeutics |
| Pfizer | Escazu, Costa Rica | Sterile Injectables |
| Ranok Therapeutics | Hangzhou , China | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| Avida Biomed | , | Acquired by Agilent, Jan 2023 |
| Aquaro Histology | , | Website down Jan 2020 - Dec 2020; fka Aquaro Biosystems |
| Jacobus Pharmaceuticals | , | No website Aug 2020 - Nov 2023; Local compounding pharmacy with real drug approval |
| Siga | New York, NY | Small Molecules |
| Hikma | London, UK | Medication Delivery |
| BioNTech | Gaithersburg , MD | mRNA, Vaccines, Biologics |
| GeneLogic | , | Bought by Ocimum, Oct 2007, $10M; bankrupt Dec 2011 |
| Multiply Labs | San Francisco, CA | Robotics for Cell Therapy Manufacturing |
| Virios Therapeutics | , | Renamed Dogwood Therapeutics, Oct 2024 |
| NuvoAir | Stockholm, Sweden | Digital Respiratory Monitoring |
| Lypro Biosciences | , | Acquired by Cerenis Therapeutics, Nov 2017 |
| Amalgamated Research | Twin Falls, ID | High-efficiency separation, mixing, and distribution technologies |
| Lacamas Laboratories | Portland, OR | Pharmaceutical Intermediate Manufacturing |
| BrightSpec | Waltham, MA | Molecular Rotational Resonance Instruments & Software |
| Machine Solutions | Flagstaff, AZ | Device Manufacturing |
| Samplix | Birkerød, Denmark | Droplet-based instrument to enable function first analysis at single-cell resolution |
| , | Renamed Lakefront Biotherapeutics, May 2026 | |
| Boreal Genomics | , | Shut down Nov 2023; Website down Apr 2023 - Sep 2023 |
| CyDex Pharmaceuticals | , | Acquired by Ligand Jan 2011 |
| EndoSound | Portland, OR | Endoscopic Ultrasound |
| Baxter | Cartago, Costa Rica | Medication Delivery |
| St. Jude Medical | , | Acquired by Abbott, Jan 2017, $25B |
| BioCogito | , | Website down Oct 2021 - Mar 2022 |
| Savage Laboratories | , | Was part of Fougera which was acquired by Sandoz, Jul 2012 |
| , | Website down Jan 2026 - Mar 2026 | |
| PharmaForm | , | Bought by Biotech Investment Group, Relaunched as Formex Jul 2013 |
| Syngulon | Charleroi, Belgium | Microbial fermentation |
| Ryvu Therapeutics | Krakow, Poland | Small molecule for cancer |
| Fujifilm Diosynth | Morrisville, NC | Biologics Development & Manufacturing |
| ViewRay | , | Shut down Oct 2023; Chapter 11 Bankruptcy, Jul 2023 |
| Endoclear | , | Acquired by Avanos, Nov 2019 |
| Apotech Consulting | London, UK | Life Science Consulting |
| Chase Pharmaceuticals | , | Acquired by Allergan, Nov 2016, $125M |
| Myllia Biotechnology | Vienna, Austria | Single Cell CRISPR Screens |
| Genomic Health | , | Acquired by Exact Sciences, Nov 2019, $2.8B |
| Lubrizol Life Science Health, CDMO Division | , | Acquired by Agno Pharma, Reverted back to being called Particle Sciences Dec 2023 |
| Taurus Biosciences | , | Acquired by Ligand Pharmaceuticals, Sep 2020, $5M |
| Capricor Therapeutics | San Diego, CA | Cell and exosome-based therapies for rare diseases |
| Adastra Pharmaceuticals | , | Sold only product to Cothera Bioscience, Oct 2021; fka Tragara Pharmaceuticals |
| TheraIndx Lifesciences | Bangalore , India | Preclinical Services |
| Monteris Medical | Minnetonka, MN | Neurosurgical Devices |
| Diagonal Bio | Lund, Sweden | Rapid Pathogen Diagnosis |
| Atox Bio | , | Website down Sep 2022 - Feb 2023 |
| Adhesys Medical | , | Bought by Grunenthal, Apr 2017; fka Medical Adhesive Revolution |
| UroGen Pharma | Ra’anana, Israel | Sustained release, hydrogel-based, formulations |
| Epitopea | Montréal, QC | Therapeutics targeting a novel class of tumor-specific antigen |
| Blue Ash Therapeutics | , | Product Acquired by Forest Labs |
| IngeneOx Therapeutics | Oxford, UK | Precision therapies and vaccines for different cancer indications |
| Hammock Pharmaceuticals | , | Outlicensed some things Dec 2018, no info on whether they do anything else, website gone |
| Verinata Health | , | Acquired by Illumina, Jan 2013, $350M+ |
| Amgen | Louisville, KY | Small Molecules, Biologics |
| Azaya Therapeyutics | , | Main assets bought by Cytori, Jan 2017 |
| Microbiotica | Cambridge, UK | Gut Bacteria Phenotype to Biomarker/Therapeutics |
| Aarvik Therapeutics | Hayward, CA | Antibody-Drug Conjugates |
| JVP Labs | St. John's, NL | Non-invasive device to measure cardiac filling pressures |
| Koronis Biomedical Technologies | Minneapolis, MN | Contract Medical Device Development |
| cGMP Validation | Kansas City, MO | Validation & Compliance Services |
| Medtronic | Danvers, MA | Medical Devices |
| T-Neuro Pharma | , | Renamed T-NeuroDx, Jul 2025 |
| Biochempeg | , | Renamed Biopharma PEG Scientific, Jan 2022 |
| SeaGen | , | Acquired by Pfizer, Dec 2023, $43B |
| , | Shut down Jan 2024 | |
| MacroCyclics | , | Acquired by Areva, Oct 2011 |
| Valneva | Bethesda, MD | Vaccines (Marketing) |
| Emergent BioSolutions | Lansing, MI | Biologics, Contract Manufacturing, Biodefense |
| Efferent Labs | Buffalo, NY | Implantable biosensors |
| Synergy Bioscience | Dallas, TX | Analytical Chemistry, Microbiology |
| Suneva Medical | , | Acquired by Tiger Aesthetics, Oct 2024 |
| Spring Science | , | Platform acquired as they wound down, Mar 2025; fka Spring Discovery |
| , | Website down Aug 2025 - Jan 2026 | |
| GeneTx Biotherapeutics | , | Acquired by Ultragenyx, Jul 2022, $75M |
| , | No news 2019 - Sep 2025 | |
| TomegaVax | , | Acquired by Vir Biotechnology, Jan 2017 |
| Arius Pharmaceuticals | , | Acquired by BioDelivery Sciences, Aug 2004 |
| BrickBuilt Therapeutics | , | Acquired by DermBiont |
| MabPrex | , | Out of business, 2016 |
| , | Website down Oct 2025 - Feb 2026 | |
| Sterna Biologicals & KG | Marburg, Germany | Antisense Molecule - DNAzyme |
| Emedgene Technologies | , | was partnering with Illumina, then became "an Illumina company" with no news |
| ASOthera Pharmaceuticals | , | Changed name to Stoke Therapeutics, Mar 2017 |
| Roivant Sciences | Basel, Switzerland | Alliances, Collabs, Partnerships |
| Auro Vaccines | Pearl River, NY | Vaccines |
| Novo Nordisk | Tianjin, China | Diabetes, obesity, liver disease and other therapeutic areas |
| ProteoVec | , | Website gone Jul 2015 |
| ImClone | , | Bought by Lilly, Oct 2008, $6.5B |
| |
Budapest, Hungary | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Crystallics | , | Merged with Pharmavize 2016, Renamed Ardena |
| BioSolutia | , | Acquired by CareMetx, Oct 2018 |
| Sanochemia Diagnostics | Neufeld an der Leitha, Austria | MRI Contrast Agents |
| Eppendorf | Groningen, Netherlands | Wide Range of Scientific Products |
| NantOmics | El Segundo, CA | Genomic Diagnostics |
| Allevi | , | Acquired by 3D Systems, May 2021 |
| Mizuho OSI | Union City, CA | Surgical / hospital tables |
| Avisa Pharma | , | Renamed Avisa Diagnostics |
| Sofpromed | Palma de Mallorca, Spain | CRO for phase I-IV clinical trials. Regulatory, monitoring, and pharmacovigilance services, Contract Manufacturing |
| Advanced Cell Technology | , | Changed name to Ocata Therapeutics, Nov 2014 |
| Eos Biosciences | , | Shut down Oct 2020 |
| Protein Biotechnologies | , | Website five years stale, ancient-looking Mar 2024 |
| Y Biologics | Daejeon, Korea | Antibody Therapeutics |
| Mesoblast | New York , NY | Regenerative Medicine |
| Inflammix | , | Renamed AnchorBio Solutions |
| Chronus Health | , | Website down Mar 2025 - Aug 2025 |
| , | Acquired by Valerio Therapeutics, Sep 2024 | |
| BioCity Biopharma | Wuxi, China | Small Molecules, Antibodies |
| , | Website down Jul 2025 - Jan 2026 | |
| Sound Pharmaceuticals | Seattle, WA | Hearing Loss Treatment |
| Alamar Biosciences | Fremont, CA | Proteomic Liquid Biopsy Platform |
| 4P Therapeutics | , | Acquired by Nutriband, Apr 2018 |
| |
Springfield, MO | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Missouri is a stand-alone full service Clinical Trials Unit, with a central safety lab, PBMC lab and leukopak (cell therapy) facility. |
| Colby Pharmaceuticals | , | Website down Aug-Oct 2018; Active in CA database Oct 2018 |
| TissueGen | Irving, TX | Polymer-based Drug Delivery Systems |
| Aranscia | Houston, TX | Diagnostic Software |
| Nanopath | Cambridge, MA | Molecular Diagnostics for Women |
| OcuNexus Therapeutics | , | Rebranded/Merged with Inflammx Therapeutics, Dec 2021 |
| Cardio-Renal | , | Website down Jun 2024 - Nov 2024 |
| Bicycle Therapeutics | Cambridge, MA | Peptides |
| CeQur | Greenville, SC | Insulin pump |
| Neugenesis | , | Bought by Intrexon, 2011 |
| |
Buffalo, NY | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Renalytix | New York, NY | AI-enabled Clinical Diagnostics |
| TIB Molbiol | Berlin, Germany | Reagents for research and medical diagnostics |
| Tessera Therapeutics | Somerville, MA | Gene Writing |
| Lakefront Biotherapeutics | Leiden, Netherlands | Drug & Antibody Therapy Discovery |
| GSK | Brentford, UK | Small Molecules, Vaccines, Biologics |
| Novonesis | Franklinton, NC | Enzymes, Biologic Reagents |
| Clal Biotech | , | Renamed Luc therapeutics, renamed Cadent, 2017 |
| Viracta Therapeutics | , | Winding down Feb 2025; Went public via Reverse Merger of Sunesis, Feb 2021 |
| Protypia | , | |
| Cambrex | High Point, NC | Small Molecules Research, Development & Manufacturing Services |
| BenchSci | Toronto, ON | AI-assisted reagent/antibody selection |
| Worldwide Clinical Trials | Mexico City, Mexico | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Bionical Emas | Willington, UK | Clinical Development, Early Access Programs and Clinical Trial Supply |
| Neovacs | Suresnes, France | Cytokine Immunotherapy |
| MirImmune | , | Acquired by Rxi Pharma, Jan 2017, stock |
| Pulsar Vascular | , | Bought by J&J Jul 2017 - Became part of Cerenovus; Previously acquired by Codman Neuro, Dec 2016 |
| Genyro | San Francisco, CA | DNA Construction Technology |
| Tolmar | Buffalo Grove, IL | Small Molecules |
| Seelos Therapeutics | New York, NY | Small Molecules, Ketamine |
| JSS Medical Research | Montreal, QC | Clinical Research & Consulting |
| Chemic Laboratories | , | Acquired by Solvias, Jun 2021 |
| Volcano | , | Bought by Philips, Dec 2014, $1.2B |
| Getinge | Tournefeuille, France | Medical Technology |
| Ipsen | Signes, France | Small Molecules, Biologics |
| Imaginostics | Orlando, FL | Contrast-enhanced MRI |
| IgGenix | South SF, CA | Allergy Antibody Therapy |
| Lipid Knowledge | , | Website gone, reported as closed on Google, Jan 2024 |
| Therapeutic Human Polyclonals | , | Acquired by Roche, Apr 2007, $56.5M |
| Seranova Bio | South SF, CA | Autoantibody Discovery |
| Actimus Bio | Visakhapatnam, India | Contract Research Services |
| Sanofi | Paris, France | Small Molecules |
| Oxyrane | , | Dissolved Jan 2024, per CEO linkedin post |
| Singer Instruments | Watchet, UK | Laboratory automation |
| Stason Pharmaceuticals | Irvine, CA | CDMO |
| OCT Clinical Trials | , | Merged with Palleos Healthcare, Jan 2025 |
| AmpliMed | , | Seems inactive, Restructuring 2010. Website copyright 2008. |
| Biomerics | Salt Lake City, UT | Contract Manufacturer - Biomedical Polymers |
| Xtremity | , | Seems gone, May 2023; aka Medical Creations Inc |
| Dynex Technologies | Denkendorf, Germany | Microplate Readers, Technology |
| Aspir-tek | , | Website gone Oct 2018; Presumed Gone |
| Boragen | , | Renamed Reactive Biosciences |
| Aurevia | Uppsala, Sweden | Clinical Research Organizations |
| CorMatrix Cardiovascular | , | Bought by Aziyo Biologics, May 2017 |
| Single Cell Discoveries | Utrecht, Netherlands | Single-cell sequencing provider |
| California Stem Cell | , | Bought by NeoStem, renamed NeoStem Oncology May 2014 |
| United States Biological | Salem, MA | Antibodies, Lab Supplies |
| Vivotecnia | Madrid, Spain | Toxicology Contract Research |
| NanoMedica | , | CEO has about 6 more important jobs, Apr 2020 |
| Calvert Laboratories | , | Acquired by Altasciences, May 2021 |
| Cycuria Therapeutics | Graz, Austria | Protein Therapies |
| Contura | , | Acquired by Axonics, Feb 2021, $200M |
| Expesicor | , | Website under construction, Jun 2021 - Dec 2021 |
| AbbVie | Wiesbaden, Germany | Small Molecules, Biologics, Devices, Diagnostics |
| Sapreme Technologies | Utrecht, Netherlands | Macromolecule Therapies That Circumvent Endosomal Entrapment |
| Nephros | South Orange, NJ | Dialysis Devices |
| Iontas | , | |
| NextStep Arthropedix | Akron, OH | Hip Implant |
| Northfield Laboratories | , | Bankrupt 2009 |
| Neuland Laboratories | Princeton, NJ | API Manufacturer |
| Aiforia Technologies | Helsinki, Finland | AI solutions for Image Analysis |
| BioElectron Technology | , | Assets Acquired by PTC Therapeutics, Oct 2019 |
| GlycoEra | Wädenswil, Switzerland | Custom Glycan Platform |
| Diffuse Bio | San Carlos, CA | Generative AI for Protein Design |
| Comera Life Sciences | , | Website down Sep 2024 - Mar 2025; Strategic Alts, Dec 2023; fka ReForm Biologics |
| Cell Pathways | , | Acquired by OSI Pharmaceuticals, Feb 2003, $32M |
| Arpida | , | Acquired by Evolva, Sep 2009 |
| CIT Sensors | , | Website down Aug 2024 - Mar 2025 |
| Cardio3 Biosciences | , | Renamed Celyad, Apr 2015 |
| NinePoint Medical | , | Seems gone Sep 2020 |
| Patheon | Ferentino, Italy | Contract Manufacturing and Development |
| Celunol | , | Merged with Diversa to become Verenium |
| DNAWrite | , | Renamed Camena Bioscience, Sep 2017 |
| Zoll | Pittsburgh, PA | Medical Devices, Defibrillators |
| Ascendas Genomics | , | No website, no info Oct 2022 - May 2022 |
| Promius Pharma | , | Sold off products Apr 2019; Dr. Reddy's subsidiary |
| Encompass Pharmaceutical Services | , | Website down Sep 2023 - Mar 2024 |
| Eko Devices | Emeryville, CA | Digital Stethoscope |
| CBM Biopharma | , | Shut down Nov 2020 |
| Tfarma | , | Aquired by Enteralia Bioscience, Nov 2024 |
| Validant | , | Renamed Eliquent Life Sciences |
| Signatur Biosciences | London, UK | PCR Platform |
| RoosterBio | Frederick, MD | MSCs derived from bone marrow |
| Warner-Lambert | , | Bought by Pfizer Feb 2000 $90B |
| NeuroCog Trials | , | Renamed VeraSci, Oct 2018 |
| Nuevolution | , | Bought by Amgen May 2019 |
| Accelerated Pharma | , | Website taken over, Aug 2024 |
| Cadena Bio | , | Company was either renamed or reformed as Kaleido, 2017 |
| SynapDx | , | Shut down, Mar 2017 |
| Selcia | , | Acquired by eurofins, Jan 2018 |
| TissueNetix | , | Gone Feb 2018 |
| Maxivax | , | Renamed Release Therapeutics |
| Qualyst | , | Acquired by BioIVT, Sep 2017 |
| Grand River Aseptic Manufacturing | Grand Rapids, MI | Contract Aseptic Manufacturing |
| DIMERx | , | Business filings late Mar 2023 - Mar 2025 |
| Vasade Biosciences | , | Gone |
| EpiCypher | Durham, NC | Epigenetic Research Products |
| Cetero Research | , | Renamed PRACS Institute |
| Noxilizer | Hanover, MD | NO2-based Sterilization |
| Monoceros Biosystems | San Diego, CA | Bioinformatics Services |
| Apertor Pharmaceuticals | South San Francisco, CA | Molecular glues for therapeutic applications in oncology |
| Exergen | Watertown, MA | Noninvasive Thermometers |
| Abide Therapeutics | , | Acquired by Lundbeck, May 2019, $250M |
| BioRealm | Monument, CO | Innovative genomic and artificial intelligence solutions |
| Ripple Therapeutics | Toronto, ON | Improving ophthalmic therapeutics with controllable, sustained drug delivery |
| Atrin Pharmaceuticals | , | Acquired by Aprea Therapeutics, May 2022 |
| Novopharm Biotech | , | Renamed Viventia Biotech, 2000 |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| DNAprint Genomics | , | Acquired by Nanobac Pharmaceuticals, Feb 2008 |
| PostEra | Boston, MA | Machine Learning Medical Chemistry |
| Clade Therapeutics | , | Acquired by Century Therapeutics, Apr 2024 |
| RaySearch Laboratories | Tokyo, Japan | Cancer Research Software |
| Anergix | , | Shut down Mar 2009 |
| International Process Solutions | Irvine, CA | Calibration, validation, preventative maintenance, and data management services |
| Zafgen | , | Merged with Chondrial Therapeutics, May 2020, became Larimar Therapeutics |
| Analyticon Biotechnologies | Lichtenfels, Germany | In-Vitro Diagnostics |
| Aliquot Solutions | , | Shut down Oct 2024 |
| SMC | Somerset, WI | Autoinjector platform, sterile filling, pharma services |
| HighTide Therapeutics | Shenzhen, China | Small Molecules |
| Versa Vascular | Santa Cruz, CA | Tricuspid Repair solution |
| Esteve | Barcelona, Spain | Small Molecules, Gene Therapy |
| Ambest Pharmaceuticals | , | Bought by Sihuan Pharmaceutical, Mar 2017, $160M |
| aap Implantate | Berlin, Germany | Trauma products for orthopedics |
| Iron Horse Diagnostics | , | Everyone gone Oct 2022 |
| Orchid Orthopedic Solutions | Sheffield, UK | Contract Medical Device Work |
| AqVida | Hamburg, Germany | Finished dosage form manufacturer for oncology |
| EnFuego Therapeutics | Chapel Hill, | RNA-based Cancer Therapies |
| Telix Pharmaceuticals | Brisbane, Australia | Radio immunotherapy |
| Neuronoff | Cleveland, OH | Pain Relief Implant |
| Xenocor | Salt Lake City, UT | HD laparoscopic imaging system |
| Simsen Diagnostics | Göteborg, Sweden | ctDNA Analysis |
| Chimera Biotec | Dortmund, Germany | Large molecule bioanalytical services using MSD, ELISA, SIMO, and Imperacer platforms |
| Eccrine Systems | , | Website expired Feb 2021 - May 2021 |
| Archer Research | Diepenbeek, Belgium | Medical Device CRO |
| Izumi Biosciences | , | No business filings May 2022-Sep 2024 |
| Avekshan LLC | , | Website down Oct 2022 - Feb 2023 |
| , | Website down Dec 2025 - Apr 2026; fka CereScan Corp | |
| BioSense Technologies | , | Closed according to Google, Dec 2018 |
| Wacker | Munich, Germany | Polymers, Resins |
| Zerion Pharma | , | Proprietary formulations of oral small molecule drugs |
| Cellartis | , | Acquired by Takara Bio Jul 2014 |
| |
Germering, Germany | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| AIVITA Biomedical | Irvine, CA | Stem Cell Therapy |
| Surgical Technologies | , | Website Down Nov 2022 - Mar 2023 |
| Evident Scientific | Hamburg, Germany | Laser Scanning Microscope |
| , | Acquired by Novo Nordisk, Sep 2023 | |
| VieVax | , | Gone Jan 2007 |
| Takeda | Lexington, MA | Small Molecule, Enzymes |
| Couragene | North Brunswick, NJ | Gene & Biologic Delivery |
| Genocea Biosciences | , | Winding Down May 2022 |
| Alkem Labs | Mumbai, India | Generics |
| Constructive Bio | Cambridge, UK | Synthetic Genome Technology |
| CellExSys | , | Merged into Chromos Molecular Systems, Jun 2004 |
| Celerion | Vienna, Austria | Clinical Research |
| AntlerA Therapeutics | , | Website down Aug 2024 - Feb 2025 |
| StromaCyte | , | Small time, no info. Defunct |
| Genentech | South SF, CA | Small Molecules, Biologics |
| Kosan Biosciences | , | Acquired by BMS 2008 |
| RogCon Biosciences | , | Website down Oct 2023 - Mar 2024 |
| ABF Pharmaceutical Services | , | Acquired by GBF Group Pharma, 2017 |
| Dompé | Naples, Italy | Biologics, Small Molecules, OTC |
| Conjugon | , | Changed name to Atterx Biotherapeutics late 2014/early 2015 |
| Siron Clinical | Breda, Netherlands | Clinical Research Organization |
| Single Use Support | Kufstein, Austria | Stainless Steel Enclosure for Single-Use Bags |
| , | Website down Dec 2025 - Apr 2026 | |
| Cygnal Therapeutics | , | Flagship merged it with Inzen and renamed it Sonata Therapeutics |
| Luitpold Pharmaceuticals | , | Renamed American Regent |
| Integrated Diagnostics | , | Acquired by Biodesix, Jul 2018 |
| Toxys | Leiden, Netherlands | In vitro toxicity screening solutions |
| GLG Pharma | , | Co-founder gone, seems unserious, Apr 2025 |
| SimpleTrials | Oakland, CA | CTMS/eTMF solution for CROs and Sponsors |
| Myoridge | Kyoto, Japan | 3D Cell Culture Technology |
| , | Acquired by Bruker, May 2024, €870M | |
| Harvard Bioscience | Holliston, MA | Scientific Instruments |
| ControlRad Systems | , | Website down Jan 2023 - Sep 2023 |
| Phathom Pharmaceuticals | Florham Park, NJ | Novel treatments for gastrointestinal diseases and disorders |
| Fluxergy | Mainaschaff, Germany | Diagnostic Lab-in-a-box |
| Bausch + Lomb | Bridgewater, NJ | Ophthalmology |
| Third Wave Analytics | San Francisco, CA | The world’s first user-friendly biotech LIMS built for research, NGS, clinical and GMP labs |
| Trophea | , | Liquidated, Dec 2019 |
| Scorpion Biological Services | , | Renamed Scorpius Biomanufacturing, Dec 2022 |
| GeneVia Technologies | Tampere, Finland | Data analysis services and bioinformatics consulting |
| Astellas | Shenyang, China | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Teleflex Medical | Amersham, UK | Surgical and Medical Devices |
| Seneb Biosciences | , | Gone 2017 |
| Avancell | , | No website Oct 2021 - May 2023; fka GEMoaB |
| Tryton Medical | , | Shut down Jan 2021 |
| Astrea Bioseparations | Cambridge, UK | Biologic Separation & Purification |
| , | Website taken over Oct 2025; Website down Jul 2025 - Sep 2025 | |
| Harkness Pharmaceuticals | , | Website copyright 2006 as of Nov 2019 |
| , | Mission Accomplished, May 2026; No news Jun 2020 - Sep 2025 | |
| Helix Medical | , | Changed name to Freudenberg Medical, Aug 2015 |
| Gallus Immunotech | , | Acquired by Exalpha Biologicals, Jun 2018 |
| Lusaris Therapeutics | , | Shut down May 2023 |
| Prothex Pharma | , | Website down Aug 2022 - Jan 2023 |
| deCode Genetics | Reykjavik, Iceland | Biotech Services |
| Lamellar Biomedical | , | Website down Jul 2022 - Nov 2022 |
| Lunit | Seoul, Korea | AI Image Analysis |
| CorInnova | Houston, TX | Heart Failure Treatment Device |
| Roche | Mannheim, Germany | Diagnostics |
| Novatract Surgical | , | Acquired by Caldera Medical, 2016 |
| Cancer Genetics | , | Merged with StemoniX, Mar 2021 to become Vyant Bio |
| Kerecis | Isafjordur, Iceland | Wound Healing |
| eCential Robotics | Gières, France | Surgical platform for 2D Fluoroscopy, 3D Imaging and real-time Navigation |
| , | Merged with ABX-CRO | |
| IGEM Therapeutics | , | Renamed Epsilogen, Apr 2020 |
| Expression Analysis | , | Acquired by Quintiles, Aug 2012 |
| Instylla | Bedford, MA | Embolization treatment |
| HWI Pharma Services | Rülzheim, Germany | Analytical Methods, Batch Release, Formulation, Quality |
| AmeRuss | , | Website down Oct 2021 - Jul 2022 |
| Celldex Therapeutics | Fall River, MA | Small Molecules, Biologics, Vaccines |
| InSphero | Brunswick, ME | 3D-cell-based assay solutions and scaffold-free 3D organ-on-a-chip technology |
| Biognosys | Newton, MA | Protein quantification technology, contract protein analysis |
| BDR Pharmaceuticals | Surat , India | APIs, New Age Formulations |
| Recombinant Antibody Technology | , | Dissolved May 2019 |
| Delpharm | Bladel, Netherlands | Contract Manufacturing |
| ImmunoCellular Therapeutics | , | Rebranded as EOM Pharmaceuticals, Nov 2022; Assets bought Aug 2019, $500k |
| CTI Clinical Trials | Covington, KY | Clinical Trials & Consulting |
| Eden Biologics | , | Acquired by Bora Pharmaceuticals, May 2022; fka JHL Biotech |
| Xcene Research | Lagos, Nigeria | Sub Saharan Africa CRO |
| Clinion | Hyderabad, India | eClinical and Decentralized Trials Platform |
| EyeCRO | Oklahoma City, OK | Small molecule for ophthalmic indications, preclinical services |
| Worldwide Clinical Trials | Nottingham , UK | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Sinclair Pharma | Paris, France | Aesthetic Dermatology |
| TM3 Therapeutics | , | Renamed Comet Therapeutics |
| Bridge Design | , | Acquired by Ximedica, Aug 2015 |
| Scivita Medical | Suzhou, China | Diagnostic Imaging and Devices |
| 3DBio Therapeutics | , | Renamed PrintBio |
| Cell Mogrify | , | Renamed Mogrify, Mar 2019 |
| RGenix | , | Renamed Inspirna, Sep 2021 |
| Bracco | Milan, Italy | Imaging |
| PurMabiologics | Oklahoma City, OK | Monoclonal Antibody Production |
| Acuitas Therapeutics | Vancouver, BC | Acuitas provides delivery solutions for molecular therapeutics using lipid nanoparticles (LNP) |
| , | Website down Oct 2025 - Feb 2026 | |
| Coastar Therapeutics | San Diego, CA | Cell Membrane Coating Technology |
| Innogenetics | , | Acquired by Fujirebio Europe, Sep 2010 |
| Bipharm | , | Website down Mar 2025; business filings late, Mar 2024 - Mar 2025 |
| ImmuRx | , | Gone, not sure what happened |
| Acclarent | , | Acquired by Integra LifeSciences, Mar 2024; Bought by J&J, Dec 2009, $785M |
| E25Bio | , | Shut down after angering FDA with Covid test, 2022 |
| VBI Vaccines | Cambridge, MA | Vaccine Development |
| Santa Cruz Biotechnology | Dallas, TX | Antibodies |
| Genomatica | San Diego, CA | Biologically Produced Chemicals |
| DiabetOmics | , | Renamed Modality Dx, Jun 2025 |
| Elevation Pharmaceuticals | , | Bought by Sunovion, $430M, Aug 2012 |
| Garuda Therapeutics | , | Renamed Stratus Therapeutics, May 2025 |
| Pulmongene | Beijing, China | Therapies for pulmonary, fibrotic, and autoimmune diseases |
| OsteoSee | , | Website down Oct 2022 - Mar 2023 |
| joimax | Irvine, CA | Endoscopic Minimally Invasive Spinal Surgery |
| Benten BioServices | , | Acquired by Deltagen, Dec 2009 |
| BBI Solutions | Portland, ME | Antibodies, Sera, Enzymes, Contract Work, etc. |
| Conrig Pharma | , | Website down Jan 2023 - Jul 2023 |
| , | Website down Jul 2025 - Dec 2025 | |
| ADS Biotechnology | , | Bankrupt 2014 |
| Health Decisions | , | Acquired by Premier Research, Jul 2021 |
| Aurigon Life Science | Dunakeszi, Hungary | Toxicology, pharmacology, testing |
| Prostrakan | , | Acquired by Kyowa Hakko Kirin; renamed Kyowa Kirin Apr 2016 |
| BRAND | Wertheim, Germany | Liquid Handling |
| Vantive | Deerfield, IL | Vital organ therapy products and digital solutions |
| Buckeye Pharmaceuticals | , | Ancient Website Nov 2019, last updated in 2006, presumed defunct |
| SRS Medical | Feeding Hills, MA | Prostatic stent, urologic devices |
| SRI International | Menlo Park, CA | Independent Research |
| Charles River Laboratories | Wayne, PA | Biologics development, R&D, and testing |
| Diatranz | , | Changed name to Living Cell Technologies, 2003 |
| , | Website down Sep 2025 - Dec 2025 | |
| Cardialysis | Rotterdam, Netherlands | Cardiology Clinical Trials |
| Liom | Pfäffikon, Switzerland | Continuous Biomarker Monitoring |
| , | Acquired by Sanofi, Aug 2025, $600M | |
| Quadrants Scientific | , | Acquired by Infinity Laboratories |
| SpectraWAVE | Bedford, MA | Medical Imaging Platform |
| Sapphire Biotech | , | Acquired by AXIM Biotechnologies, Jan 2020 |
| Sapphire Therapeutics | , | Acquired by Helsinn 2009 |
| Ben Venue | , | Closed Late 2013, Early 2014 |
| Liberate Bio | Boston, MA | Non-viral delivery technologies for nucleic acid cargoes such as ASOs, siRNAs, mRNAs, and encoded gene editors |
| Zag Bio | Cambridge, MA | Thymus-targeting bifunctional antibodies for diabetes |
| OperaCRO | , | Now part of Tigermed |
| Argo Biopharma | Shanghai, China | siRNA Drugs |
| CMP Pharma | Farmville, NC | Small Molecules |
| Confluence Life Sciences | , | Acquired by Aclaris Therapeutics, Aug 2017, $10M cash + $10M shares |
| Pulse Systems | , | Acquired by Heraeus, 2020 |
| Forty Seven | , | Acquired by Gilead, Apr 2020, $4.9B |
| Whitecap Biosciences | , | Acquired by Bausch + Lomb, Jan 2025 |
| Chiasma Pharma | , | Acquired by Amryt Pharma, Aug 2021 |
| PineTree Therapeutics (2) | Cambridge, MA | Antibody Therapy, Virus-Targeting Recombinant Agent |
| Sanofi-Synthelabo | , | Merged with Aventis, 2004 to become Sanofi-Aventis; Formed in 1999 upon the merge of Sanofi & Synthelabo |
| Phosphagenics | , | Renamed Avecho Biotechnology |
| TargetRx | Shenzhen, China | Small Molecules Targeting Cancer |
| Recurv Pharma | , | No website Feb 2023 - Jan 2025 |
| Vector BioPharma | , | Website down Jan 2024 - Jul 2024 |
| Telesta Therapeutics | , | Bought by ProMetic, Aug 2016, $34M |
| Ventria Bioscience | , | Website down Oct 2023 - Mar 2024 |
| Lo.Li. Pharma | Rome, Italy | Medical Devices |
| Oncotec Pharma Produktion | Dessau-Roßlau , Germany | Aseptically produced cytostatics |
| Vectans Pharma | Saint-Cloud, France | Small molecule for sexual health |
| Silk Road Medical | , | Acquired by Boston Scientific, Sep 2024, $1.16B |
| MabPlex | Shandong, China | Biologics CMO, Contract research |
| MicroGenDX | Lubbock, TX | Molecular Diagnostics, Sequencing |
| Lupin | Baltimore, MD | Generics |
| Xoma | , | Sold Berkeley MFG facility to Agenus, Nov 2015, repositioned as a royalty aggregator |
| Avioq | Durham, NC | HIV Diagnostics |
| Alpha-5 integrin | , | Acquired by Pasithea Therapeutics, Jun 2022 |
| Circadian Technologies | , | Changed name to Opthea, Dec 2015 |
| ZoBio | Leiden, Netherlands | Contract Drug Discovery |
| Tenaxis Medical | , | Bought by The Medicines Company, Sep 2013 |
| Texas Biotechnology | , | Renamed Encysive Pharmaceuticals, May 2003 |
| Cosette Pharmaceuticals | Lincolnton, NC | Generics |
| Medtronic | Minneapolis, MN | Medical Devices |
| Sypharma | Dandenong, Australia | Contract Small Molecule Manufacturing |
| , | Website down Jan 2026 - May 2026 | |
| Eurofarma Laboratórios | São Paulo, Brazil | Small Molecules, Generics |
| SmithKline Beecham | , | Merged with Glaxo Wellcome in 2000 to form GSK |
| Serotiny | , | Acquired by J&J, 2023 |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Lidak Pharmaceuticals | , | Changed name to Avanir Pharmaceuticals, 1998 |
| Medistem | , | Bought by Intrexon Dec 2013 |
| Thrasos Therapeutics | , | Employees all gone, Mar 2018 |
| PK Biosciences | , | Website down Sep 2024 - Mar 2025 |
| SourceMDx | , | Assets Sold |
| Biomunex Pharmaceuticals | Paris, France | Bispecific Antibodies |
| Helix Nanotechnologies | Boston, MA | DNA Therapy |
| Worldwide Clinical Trials | Zagreb, Croatia | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Advancis Pharmaceutical | , | Changed name to MiddleBrook Pharmaceutical, Jun 2007 |
| BioBlast Pharma | , | Shell reverse-merged with Enlivex Therapeutics, Nov 2018 |
| Italfarmaco Research | Cinisello Balsam, Italy | Pharmaceuticals and fine chemicals |
| ReFlow Therapeutics | , | Renamed CorFlow Therapeutics, May 2017 |
| Twister Biotech | , | Renamed Velvet Therapeutics, Apr 2024 |
| |
Camarillo, CA | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| New Horizons Clinical Research | , | Acquired by Velocity Clinical Research, Nov 2020 |
| Isolere Bio | Durham, NC | Chromatography-free solutions for the purification of biological therapeutics |
| DoubleRainbow Biosciences | Lexington, MA | Drug discovery through genetic analysis of nature |
| Bend Bioscience | Gainesville, GA | CDMO, Solid oral dosage, controlled substances |
| American Biomedica Corp | , | Website taken over Aug 2020 |
| IBA Analytics | , | Website gone Jul 2015 |
| SignalChem Lifesciences | , | Acquired by Sino Biological, Oct 2023 |
| AkiraBio | Wellesley, MA | Treatment for Sickle Cell and Thalassemia |
| Xendo | , | Acquired by ProPharma, Jul 2018 |
| Stoke Therapeutics | Bedford, MA | Antisense Oligonucleotide Medicines |
| Tolmar | Fort Collins, CO | Small Molecules |
| Molecular Insight Pharmaceuticals | , | Acquired by Progenics, Jan 2013 |
| , | Acquired by Fulgent Genetics, Mar 2026 | |
| Alaven Pharmaceutical | , | Bought by Meda, $350M, Oct 2010 |
| Analytical Bio-Chemistry Laboratories | , | Acquired by EAG, Jul 2015 |
| Daan Biotherapeutics | Seoul, Korea | Cell Therapies, Antibodies, Small Molecules |
| Synphora | , | Website down Sep 2023 - Mar 2024 |
| Hepagene Therapeutics | Nanjing, China | Liver Therapeutics |
| Minaris | Philadelphia, PA | CGT CDMO and Biosafety Testing Lab |
| Cocrystal Pharma | Bothell, WA | Antivirals |
| TriAct Therapeutics | , | Business filings late Apr 2023; No website Jul 2021 - Jul 2024 |
| Pfizer | Ringaskiddy, Ireland | API production |
| NewAmsterdam Pharma | Naarden, Netherlands | Small Molecule |
| Johnson and Johnson Innovative Medicine | Spring House, PA | Small Molecules, Biologics |
| NeuroGate Therapeutics | , | Dissolved, Dec 2014 |
| NanoSurface Biomedical | , | Renamed Curi Bio, Jul 2020 |
| OPM Biosciences | Shanghai, China | Cell Culture Media, Reagents, Services |
| Shengeke Pharmaceuticals | , | Website hijacked, Feb 2025 |
| Chester Valley Pharmaceuticals | , | Bought by Graceway |
| Occulo | , | Website down Apr 2021 - Sep 2021 |
| Elixell Therapeutics | , | Website down Feb 2023 - Sep 2023 |
| Pier Pharmaceuticals | , | Merged with Cortex Pharmaceuticals Aug 2012 |
| Stratpharma | Basel, Switzerland | Scar Therapies |
| BioCryst Pharmaceuticals | Durham, NC | Small Molecules |
| Crucell | , | Acquired by J&J, Mar 2011, $2.3B |
| Scripta Therapeutics | Oxford, UK | AI, imaging, and patient-derived models for drug discovery |
| DynoSense | , | Shut down Sep 2022 |
| Korysso Therapeutics | , | Renamed Magnolia Tejas, 2018 |
| Tal Medical | , | Gone |
| Kano Therapeutics | Cambridge, MA | Design and engineering of novel genetic vectors |
| Neothetics | , | Merged with Evofem Jan 2018; fka Lithera, Site down Jun 2018 |
| Shape Memory Therapeutics | , | Renamed Shape Memory Medical |
| DepYmed | Farmingdale, NY | Small molecules with copper chelating properties |
| Artizan Biosciences | , | Website hijacked Nov 2023, down Aug 2023 - Oct 2023 |
| SomaLogic | Boulder, CO | Blood Analysis |
| Diagnostic Hybrids | , | Acquired by Quidel, Nov 2013, $130M |
| Illumicure | , | Renamed Luma Therapeutics, Apr 2018 |
| Nelson Laboratories | Salt Lake City, UT | Microbiology Testing |
| Vizgen | Cambridge, MA | Next-generation spatially resolved, single-cell transcriptomics |
| Dako | , | Bought by Agilent, May 2012, $2.2B |
| Advaxia Biologics | Pomezia, Italy | Adenovirus-based vaccine CDMO |
| Echo | San Diego, CA | Microscopy |
| Amsino | Pomona, CA | Disposable Devices, Contract Manufacturing |
| Enigma Therapeutics | , | Acquired by NeuroDiscovery, Feb 2013 |
| Element | Acton, MA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| IPS Therapeutique | Sherbrooke, QC | Cardiac Safety Evaluation of Drugs |
| Dipharma | Baranzate, Italy | APIs, Generics |
| CytoPherx | , | Rebranded as SeaStar Medical, 2018 |
| , | Part of SBO Hearing, Feb 2026 | |
| Capio Biosciences | Madison, WI | Cancer Diagnostic Technology |
| Philochem | Otelfingen , Switzerland | Chemical Pharmaceutical Products, Imaging Markers |
| Innoviva Specialty Therapeutics | Waltham, MA | Specialty Pharmaceuticals |
| CytoVera | , | Gone June 2017 |
| Rhythm Biosciences | Melbourne, Australia | Colon Cancer Diagnostic |
| Hetero | Hyderabad, India | APIs, Generics, Biosimilars |
| Sensiq Technologies | , | Products sold to Pall Jan 2017; Acquired by Private Equity, Jul 2012; Employees created new company, BioInSpire |
| Newgen Biopharma | , | Suspended trading due to scandal |
| Medicis Pharmacal | , | Bought by Valeant Pharmaceuticals Dec 2012 |
| Regulus Therapeutics | , | Acquired by Novartis, Jun 2025, $1.7B |
| Eppendorf | Singapore, Singapore | Wide Range of Scientific Products |
| Stago | Gennevilliers, France | Diagnostics |
| Anelixis Pharmaceuticals | , | Renamed Anelixis Therapeutics, Dec 2016 |
| OmniAb | Durham, NC | Antibody repertoires and high-throughput screening technologies |
| Parallax Health Sciences | , | Website down Apr 2022 - Jul 2022 |
| ATB therapeutics | Marche-en-Famenne, Belgium | Antibody-Toxin Treatments |
| AliveDx | Eysins, Switzerland | Diagnostics |
| Belay Diagnostics | Chicago, IL | Next-gen sequencing to detect aneuploidy and mutations with our cerebrospinal fluid testing platform |
| Tgen Tech | , | Renamed Annoviant |
| Aquarius Biotechnologies | , | Acquired by Matinas Biopharma, Jan 2015 |
| Macrogen | , | Renamed Psomagen, 2019 |
| Bioqual | Rockville, MD | Research, development, consulting, and testing / assay services |
| Elan | , | Bought by Perrigo, Dec 2013 |
| Novo Nordisk | Dublin, Ireland | Diabetes, obesity, liver disease and other therapeutic areas |
| Ucello Therapeutics | Chengdu, China | CAR-T Therapies |
| MagBio Genomics | Gaithersburg, MD | DNA sampling, isolation; Lab products |
| iOMEDICO | Freiburg, Germany | CRO specializing in oncology and hematology |
| SCM Pharma | , | Taken over by Shire, Aug 2014 |
| Luxcel Biosciences | , | Acquired by Agilent, Jan 2018 |
| Monobind | Lake Forest, CA | IVD |
| Beijing Challen Biotechnology | Beijing, China | Flow Cytometers and Related Reagents |
| , | Renamed Bandit Biosystems, Mar 2026 | |
| Getinge | Växjö, Sweden | Medical Technology |
| , | No news 2019 - Jan 2026 | |
| ICDD-SAS | , | Website down Oct 2020 - Feb 2021 |
| Quanta BioDesign | , | Acquired by Vector Laboratories, Jul 2023 |
| Biohaven | New Haven, CT | Small Molecules for Neurology Indications |
| Diagon | Budapest, Hungary | Hematology Reagents |
| Medtronic | Cincinnati, OH | Medical Devices |
| |
Cleveland, TN | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| MWG Biotech | , | Owned by Eurofins |
| Kinapse | , | Website down Jul 2023 - Dec 2023; Bought by Syneos Health, Aug 2018 |
| CytoMol | , | Website down Jan 2025 - Jun 2025 |
| Stada | Bad Vilbel, Germany | Generics |
| Vicus Therapeutics | , | Gone 2019 |
| , | Assets Acquired by Klotho, Sep 2025 | |
| , | Website down Jan 2026 - May 2026 | |
| Genialis | Boston, MA | Bioinformatics |
| Ash Stevens | , | Acquired by Piramal, Aug 2016, $53M |
| Aavis Pharmaceuticals | Hoschton, GA | Generics |
| Cereius | , | Acquired by Solve Therapeutics, Jun 2023 |
| Santiago Custom Chemicals | , | Renamed SigutLabs, May 2025 |
| Sandia Biotech | Albuquerque, NM | Protein & peptide analysis tools |
| Agilex Biolabs | Thebarton, Australia | Bioanalytical Clinical Testing |
| Weatherwax | , | Renamed General Proximity |
| Tego Science | Seoul, Korea | Cultured Epidermis |
| Micropore Technologies | Redcar, UK | Membrane-Based Process Equipment |
| Entrada Therapeutics | Boston, MA | Biologics delivered to cytosol |
| BEBIG Medical | Shanghai, China | Radiation Therapy Products |
| Ensemble Therapeutics | , | Closed Aug 2017 |
| Atonarp | Pleasanton, CA | Molecular Analysis by Mass Spec |
| Winco | , | Website down Feb 2023 - Jul 2023 |
| Nuclera | Billerica, MA | Desktop Bioprinting |
| AVI Biopharma | , | Renamed Sarepta Therapeutics, Jul 2012 |
| IntuiTap Medical | Houston, TX | Spinal Tap Technology |
| Tateva Therapeutics | , | No website Dec 2019 - Jul 2024 |
| Kereos | , | Seems gone |
| VaxDesign | , | Acquired by Sanofi Pasteur, Sep 2010, $55M |
| Active Pass Pharmaceuticals | , | Gone |
| Palm Beach CRO | , | Website down Sep 2021 - Jan 2022 |
| Transdermal Corp | , | Website down Jan 2020 - Oct 2020 |
| Ro5 | , | Acquired by Juvenescence, Jun 2025 |
| Alydar Pharmaceuticals | , | Gone, 2002? |
| Amolifescience | Seoul, Korea | DNA/RNA Extraction Kits |
| Tobira Therapeutics | , | Bought by Allergan, Nov 2016, $600M + milestones |
| ArKal Medical | , | Gone 2012 |
| Inductive Bio | Virtual, US | Compound Optimization |
| Senexta Therapeutics | , | Website down Jan 2023 - Jul 2023 |
| Performance Validation | Indianapolis, IN | Validation, commissioning, and quality services |
| AccelLAB | , | Acquired by Charles River, Apr 2019 |
| Inivata | , | Acquired by NeoGenomics, May 2021, $390M |
| AllerGene AI Therapeutics | Miami, FL | in vivo–delivered mRNA CAR-T cells |
| Abbott | Clonmel, Ireland | Stents |
| Siena Biotech | , | Bankrupt, Apr 2015 |
| Viveve | , | Stock worthless, employees gone Nov 2023; Website down Mar 2023 - Nov 2023 |
| Luc Therapeutics | , | Renamed Cadent Therapeutics, Oct 2017 |
| Coral Drugs | New Delhi, India | APIs |
| Twist Bioscience | Wilsonville, OR | Synthetic DNA, genes and libraries |
| Piramal | Grangemouth, UK | CDMO |
| C3 Research Associates | , | Acquired by Avance Clinical, Sep 2022 |
| Rose Pharmaceuticals | , | fka Gastrotech, Site Gone |
| NextPoint Therapeutics | Cambridge, MA | Antibody Therapies |
| Corvidia Therapeutics | , | Acquired by Novo Nordisk, Aug 2020, $725M |
| Mo Bio Laboratories | , | Acquired by Qiagen, Jan 2016 |
| Ventus Therapeutics | Waltham, MA | Small Molecules targeting proteins in the inflammasome and nucleic acid sensing signaling pathways |
| Sterling Industries | Woodbridge, ON | Medical Device Contract Manufacturing & Development |
| Zealand Pharma | Soborg, Denmark | Peptide Drugs |
| SiVEC Biotechnologies | Fort Collins, CO | Biologic Platform for Nucleic Acid Delivery |
| iCareDx | , | Renamed AcuamarkDx |
| |
Basel, Switzerland | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| G&L Healthcare Advisors | , | Renamed G&L Scientifc |
| Quintessence Biotech | , | Biomimetic Separation |
| Active Implants | , | Renamed NUsurface |
| SPT Labtech | Hertfordshire , UK | Design of Life Science Solutions |
| One Cell Systems | , | Website copyright 2003 as of Jan 2019 |
| Xcyte Therapies | , | Assets sold, shell sold to Cyclacel, Dec 2005 |
| The Clinical Trial Center | , | Website down Nov 2024 - Apr 2025 |
| Myomo | Burlington, MA | Arm brace to support and move weak arm |
| Segetis | , | Assets bought by GFBiochemicals, Feb 2016 |
| Cardiovascular BioTherapeutics | , | Renamed Venturis Therapeutics, Jan 2020 |
| Beyond Air | Rehovot, Israel | Nitric Oxide Therapy |
| Agile Sciences | , | Website down Sep 2021 - Oct 2021; Business Revoked May 2021 |
| Vivlion | Frankfurt a. M., Germany | Innovative CRISPR-enabled discovery platforms |
| AgaMatrix | , | Renamed WaveForm Diabetes, Jun 2020 |
| Modulo Bio | San Diego, CA | Small Molecules for Neurological Conditions |
| Imprimis Pharmaceuticals | , | Renamed Harrow Health, Jan 2019 |
| Dyne Therapeutics | Waltham, MA | Antibody-Oligonucleotide Treatments for Muscle Diseases |
| WaveForm Diabetes | , | Website down Aug 2023 - Apr 2024; fka AgaMatrix |
| Pulmonx | Neuchâtel, Switzerland | Lung disease treatments |
| Eolas Therapeutics | Palm Beach Gardens, FL | |
| , | Merged with Chr Hansen to become Novonesis, Jan 2024 | |
| Aspire Bariatrics | , | Shut down Apr 2022 |
| Trophogen | , | Very dated website, 2020-Dec 2024 |
| Molecular Partners | Zurich, Switzerland | Biologics |
| Delpharm | Cerano, Italy | Contract Manufacturing |
| Natco Pharma | Hyderabad, India | Generics, APIs, Contract Manufacturing |
| DiNAQOR | Schlieren, Switzerland | Gene Therapy for Heart Conditions |
| Sanuwave | Eden Prairie, MN | Shock wave technology for tissue repair and regeneration |
| Kardigan | South SF, CA | Seems to be Small Molecules |
| Innorna | Shenzhen, China | Lipid Nanoparticles |
| Karus Therapeutics | , | Ceased development, may be trying to sell product |
| Biodexa Pharmaceuticals | Cardiff, UK | Nanomedicine |
| IthenaPharma | , | Merged with Marina Biotech, Nov 2016 |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Miroculus | , | Acquired by Integra Biosciences, Mar 2023 |
| ANYO Labs | Gothenburg, Sweden | Small Molecule Drug Discovery Tools |
| Synoligo Biotechnologies | Morrisville, NC | Oligonucleotide Synthesis |
| Sirion Biotechnology | , | Acquired by PerkinElmer, Jun 2021 |
| Osprey Medical | , | Website taken over May 2024 - Sep 2024 |
| Prime Pharmaceuticals | Mumbai, India | Generics |
| Prothya Biosolutions | Budapest, Hungary | Services and plasma-derived medicinal products |
| GigaGen | San Carlos, CA | Immune therapeutics |
| Lupin | Mandideep, India | Generics |
| Genomic Testing Cooperative | Lake Forest, CA | Diagnostics |
| Cytopia | , | Acquired by YM Biosciences, Oct 2009, $14M |
| Harmony Biosciences | Plymouth Meeting, PA | Sleep & CNS disorders |
| Akrivis Technologies | , | Gone Jun 2021 |
| OHM Oncology | , | Website gone Apr 2022, no employees |
| Sigma Tau | , | Changed name to Leadient Biosciences, Feb 2017 |
| Clanotech | , | Website down Oct 2020 - Feb 2022 |
| Enzyvant Sciences | , | Merging with Altavant Sciences, Dec 2022; Acquired by Sumitomo Dainippon Pharma with four other Roivant companies, Dec 2019, $3B; |
| Palvella Therapeutics | Wayne, PA | Small Molecules |
| Geom Therapeutics | , | Website down Oct 2020 - Jan 2021, presumed gone |
| XtalPi | Shanghai, China | AI Drug Design |
| XellSmart | Shanghai, China | Cell Therapy |
| Mabgeek | Shanghai, China | Monoclonal Antibodies |
| GramEye | Osaka, Japan | AI and automation for Gram Staining |
| Zephyr AI | McLean, VA | AI Data Analysis |
| Global Blood Therapeutics | , | Acquired by Pfizer, Oct 2022, $5.4B |
| DS Biopharma | Dublin, Ireland | Bioactive Lipid Technology |
| Vertex | San Diego, CA | Small Molecules, Gene Editing, Cell Therapy |
| Avalon | , | Acquired by Nordson Medical, Aug 2014 |
| Specifar Pharmaceuticals | , | Acquired by Watson Pharmaceuticals, May 2011, $562M |
| ABL Bio | Seongnam, Korea | Antibody, Immuno-oncology |
| PharPoint Research | Durham, NC | Clinical Operations and Project Management, Data Management, Biostatistics, and Data Standardization and Warehousing |
| Epista Life Science | Hørsholm, Denmark | Consulting |
| PPD | Middleton, WI | Contract R & D, Consulting |
| Hybridoma Sciences | , | Renamed Hycor BioMedical |
| Mercator MedSystems | San Leandro, CA | Catheter-guided infusion systems |
| Pharmatrope | , | Absurd website 2020-2023 |
| Trajectum Pharma | , | Website down Feb 2025 - Jul 2025 |
| Impax Laboratories | , | Merged with Amneal, May 2018 |
| |
Oxford, UK | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Nanolabz | , | Acquired by HIL Applied Medical, Jun 2016 |
| Alacris Theranostics | Berlin, Germany | NGS Services |
| Xori | , | Antibody Platform sold between 2011-2014 |
| Cancer Therapeutics CRC (CTx) | , | Renamed Canthera Discovery, Sep 2021 |
| Strategic Diagnostic Antibodies | , | Acquired by Fitzgerald Industries, 2004 |
| Somerset Pharmaceuticals | , | Acquired by Mylan, Jul 2008 |
| Veeva Systems | Dublin, OH | Life Science Software |
| Chrysalis Biomedical Advisors | Redwood City, CA | Boutique strategy consulting firm |
| Neusoft Medical Systems | Shenyang, China | Digital Medical Treatment Equipment, Diagnostics |
| Tegra Medical | Hernando, MS | Contract Medical Device Manufacturer |
| OakLabs | Hennigsdorf, Germany | Precision Medicine using biomarkers |
| , | Website down Sep 2025 - Jan 2026 | |
| , | Acquired by HiRO, Aug 2023 | |
| 4D Molecular Therapeutics | Emeryville, CA | Gene Therapy |
| Orlance | Seattle, WA | Low-dose, needle-free vaccines and therapeutics |
| 4 Medical Clinical Solutions | Manchester, UK | Site Management |
| JPT Peptide Technologies | Berlin, Germany | Peptide products and services |
| Velcura Therapeutics | , | Website Gone |
| AbBaltis | Kent, UK | Plasmas & Sera |
| Athens Bioscience | Athens, GA | Purified human proteins |
| Enlibrium | , | Gone 2018 |
| ObsEva | , | Shut down Feb 2024 |
| VectorBuilder | Yokohama, Japan | Recombinant Vectors & Viruses |
| HT BioImaging | Hod Hasharon, Israel | Cancer Imaging |
| TCRCure | Guangzhou, China | Immune Cell Therapy |
| S-Cubed | Abingdon, UK | S-cubed is a consultancy based in the UK & Denmark with skilled staff, offering flexible services. |
| Gemin X | , | Acquired by Cephalon Mar 2011 |
| SeqRight | , | Acquired by GE Apr 2012 |
| ECI Therapeutics | Cambridge, MA | Platelet-rich plasma-derived growth factor and excipient platform |
| iRhythm Technologies | Houston, TX | Remote heart analysis |
| Impact Therapeutics | Shanghai, China | Small Molecules |
| cTRL Therapeutics | Chicago, IL | Solid Tumor-Infiltrating Lymphocyte |
| CITrials | , | Acquired by Cenexel Clinical Research, Mar 2021 |
| Adrenas Therapeutics | , | Seems rolled back into BridgeBio, Apr 2025 |
| Umlaut.bio | Heidelberg, Germany | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Zumutor Biologics | Cambridge, MA | Biologics |
| Adhaere Pharmaceuticals | , | Website gone Oct 2018, CEO gone |
| Elpidera | , | Moderna subsidiary, dissolved Sep 2017, assets went to Moderna |
| EEL transcriptomics | , | Assets acquired by Rebus Biosystems, Dec 2021 |
| Upperton Pharma Solutions | Nottingham, UK | Formulation Development, Clinical Manufacturing, Analytical Services |
| Zomanex | , | Gone Oct 2019 |
| Vijaya Pharma | , | Website down Feb 2025 - Jul 2025 |
| Biomerics | Cartago, Costa Rica | Medical device design & manufacturing |
| Kapadi | Raleigh, NC | Boutique Oncology Clinical Research Organization |
| Abexxa Biologics | , | Acquired by Boehringer-Ingelheim, Sep 2021 |
| Tenacia Biotechnology | Shanghai, China | Small Molecules |
| Pacific Edge | Dunedin, New Zealand | Cancer Diagnostics |
| Symplmed Pharmaceuticals | , | Sold product to Marina Biotech, Jun 2017 |
| Boehringer Ingelheim | Fremont, CA | Large molecule, biomanufacturing |
| Microvascular Therapeutics | Tucson, AZ | ultrasound contrast and theranostics |
| Cellexus | Dundee, UK | Single use, fully airlift, bioreactors with working volumes from 1.5L to 50L |
| Cline Scientific | , | Bankrupt Aug 2024 |
| Proxima | New York, NY | AI Protein Folding Platform |
| EndoVention | , | Website down Aug 2021 - Feb 2022 |
| Torus Biosystems | , | Business filings late Mar 2023; Website down Mar 2024 - Jul 2024 |
| Sharp | Conshohocken, PA | Commercial packaging, clinical services & sterile manufacturing, providing pharma solutions from trials to commercial launch. |
| Biotie Therapies | , | Bought by Acorda Therapeutics, Jan 2016, $363M |
| ARKRAY | Kyoto, Japan | Clinical Diagnostics |
| Glasshouse Pharmaceuticals | , | Website down Jun 2024 - Nov 2024 |
| , | Website down Jul 2025 - Jan 2026 | |
| AssayGate | Ijamsville, MD | Contract Immunoassays, Biomarker Testing |
| ChanRx | , | 2006 ChanTest spinout, changed name to Laguna Pharmaceuticals |
| Rexgenero | , | Renamed Ixaka, Jan 2021 |
| ClinServ | , | Website down Feb 2022 - Jul 2022 |
| eTheRNA immunotherapies | Niel, Belgium | mRNA Technology & production |
| Birdotech | Shanghai, China | CDRMO |
| Inpeco | Novazzano, Switzerland | Lab Automation |
| Purely Proteins | , | All employees gone, no info |
| Medtronic | Phillipsburg, NJ | Medical Devices |
| Sampled | Motherwell, UK | Biostorage |
| GPB Scientific | , | Renamed Curate Biosciences, Feb 2022 |
| Alize Pharma 3 | , | Renamed Amolyt Pharma |
| Taysha Gene Therapies | Dallas, TX | Adeno-associated virus gene therapies |
| Patheon | Monza, Italy | Contract Manufacturing and Development |
| MentiNova | , | Website down Oct 2020 - Feb 2021 |
| AlgoTherapeutix | , | Renamed AlgoTx |
| Theratechnologies | Montréal, QC | Small Molecules, Therapeutic Antibody |
| |
Bucharest, Romania | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| LeukoDx | , | Renamed Accellix, Jul 2019 |
| Lazurite | Cleveland, OH | Wireless Arthroscopic Camera |
| Oculeve | , | Bought by Allergan, Jul 2015, $125M |
| AcureX Therapeutics | , | Renamed Acurex Biosciences |
| Axion BioSystems | Atlanta, GA | Cell-Analysis Software & Systems |
| Alterome Therapeutics | San Diego, CA | Oncology Treatments |
| VaxEquity | , | Website down Apr 2024 - Sep 2024 |
| , | Website down Dec 2025 - Feb 2026 | |
| eBioscience | , | Acquired by Affymetrix, Nov 2011, $330M |
| OSE Pharma | , | Merged with Effimune May 2016, became OSE Immuno-therapeutics |
| Accellacare | Rocky Mount, NC | Clinical Research |
| MintNeuro | London, UK | Neural Implant Semiconductors |
| Harbour Antibodies | , | Acquired by Harbour Biomed, Dec 2016 |
| Hyperion Medical | , | Website down Sep 2020 - Mar 2021 |
| Cytotheryx | Rochester, MN | Hepatocyte Expansion Technology |
| Zonagen | , | Changed name to Repros Therapeutics in 2006 |
| STALICLA | Geneva, Switzerland | Autism Treatments, Diagnostics |
| Yuyu Pharma | Seoul, Korea | Small Molecules |
| |
Durham, NC | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| New Health Sciences | , | Renamed Hemanext, Oct 2017 |
| StromaBio | Solna, Sweden | Mesenchymal Stromal Cell based cell therapies |
| Metabasis | , | Bought by Ligand |
| Seres Health | , | Changed name to Seres Therapeutics, May 2015 |
| AlliedPath | , | Acquired by IRIS International, Aug 2010 |
| Sonic Clinical Trials | Macquarie Park, Australia | Clinical Lab |
| Structure Therapeutics | South SF, CA | Oral small molecule drugs that can deliver biologic-like activity and specificity |
| Gentuity | Sudbury, MA | Catheter Imaging System |
| Akela Pharma | , | Now PharmaForm |
| Atonarp | Bangalore, India | Molecular Analysis by Mass Spec |
| Archimedes Pharma | , | Acquired by ProStakan, Jul 2014, $394M |
| Xediton Pharmaceuticals | Oakville, ON | Acquisition, commercialization of various products |
| AgileBio | San Diego, CA | IT Life Science Solutions |
| Watchmaker Genomics | Boulder, CO | Genomics Contract Work |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Tacere Therapeutics | , | Bought by Benitec Biopharma Oct 2012 |
| Nanosonics | Manchester, UK | Ultrasound |
| , | Website down Jan 2026 - May 2026 | |
| Luvak Lab | , | Dissolved 2013 |
| Serentis | , | Website Gone |
| WestGene Biopharma | Chengdu, China | Gene editing, immunotherapy, biologics, adjuvants, vaccines, antibodies |
| PharmaLex | Conshohocken, PA | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| TheraBiol | , | Business Surrendered, Sep 2019 |
| Johnson and Johnson Innovative Medicine | Beerse, Belgium | Small Molecules |
| ViaCord | , | Part of PerkinElmer |
| Zavation Medical Products | Flowood, MS | Surgical, Spinal Devices |
| ACM Global Laboratories | Rochester, NY | Bioanalytical, Central Lab Services |
| Stryker | Mahwah, NJ | Medical Devices |
| CPC Scientific | Milpitas, CA | Peptides. Custom / Catalog. |
| Sutro Biopharma | South SF, CA | Biochemical Protein Synthesis Platform |
| HanAll Biopharma | , | Website down Aug 2023 - Dec 2023 |
| Perceptive | Nottingham, UK | Medical Imaging |
| Lexogen | Vienna, Austria | RNA kits |
| Molecular Infusions | , | Acquired by Surterra Wellness |
| Rapid Dose Therapeutics | Burlington, ON | Oral Drug Delivery System |
| HighPoint Solutions | , | Acquired by IQVIA, Oct 2017 |
| Amplimmune | , | Bought by MedImmune Oct 2013, $225M |
| Vertical Pharmaceuticals | Alpharetta, GA | Branded Generics |
| Drumetix Labs | Greensboro, NC | in vivo and in vitro DMPK services and bioanalytical support |
| Karcinolys | , | No website, spinout website gone Jan 2020 - Aug 2021 |
| Biovica | Uppsala, Sweden | Biomarker Cancer Diagnostics |
| , | Website down Sep 2025 - Dec 2025; fka Core Clinical Research & Consultancy | |
| Allomek Therapeutics | , | Acquired by Pasithea Therapeutics, Oct 2022 |
| DPT Laboratories | San Antonio, TX | Semi-solid & Liquids - Contract Development, MFG |
| AcSentient | , | Main assets acquired by Ista Pharmaceuticals, May 2002 |
| Amplyus | , | Renamed miniPCR |
| Fathom Pharma | , | Acquired by Consegna Pharma, Apr 2022 |
| Axcella Health | , | Renamed Axcella Therapeutics |
| PCI Pharma Services | Philadelphia, PA | Contract Manufacturing, Services |
| Molecular Assemblies | , | Now part of TriLink BioTechnologies, Jan 2025 |
| Adnexus Therapeutics | , | Bought by BMS, Sep 2007, $415M |
| XellSmart | Suzhou, China | Cell Therapy |
| Takeda | Osaka, Japan | Small Molecule, Enzymes |
| Cytes Biotechnologies | , | Renamed BeCytes Biotechnologies, Jul 2023 |
| Fresenius Kabi | Bad Homburg, Germany | Infusion Therapy |
| Ingenious Targeting Laboratory | Hollbrook, NY | Animal Models |
| MiMedx | Marietta, GA | Amniotic tissue processing and distribution |
| Robeauté | Paris, France | Neurosurgical Robotics |
| Alpax Pharmaceutical | , | Dissolved Jan 2014 |
| Bayer | Mailand , Italy | Small Molecules |
| MedNet Solutions | Minnetonka, MN | EClinical and Data Capture Software |
| R2M Pharma | South SF, CA | Drug Development Services |
| Elstar Therapeutics | , | Renamed Marengo Therapeutics, Feb 2021 |
| Vitae Pharmaceuticals | , | Bought by Allergan, Sep 2016, $639M |
| Estudysite | , | Acquired by Velocity Clinical, Dec 2020 |
| Auxocell Laboratories | , | Assets acquired by BioStem Technologies, Mar 2023 |
| EuBiologics | Seoul, Korea | Vaccines |
| PreDxion Bio | , | Renamed Refractal |
| Annova Chem | , | Gone, 2017 |
| SAGE Labs | , | Acquired by Horizon Discovery, $48M, Sep 2014 |
| Re-Vana Therapeutics | Belfast, UK | Biodegradable Drug Eluting Implant |
| Transmed Oncology | , | Gone? |
| Solaris Pharma Corporation | Bridgewater, NJ | Generics |
| , | Website down Nov 2025 - Apr 2026; Filings late Jul 2025 | |
| Humanigen | , | Website down Apr 2024 - Jun 2024; Filed Bankruptcy Jan 2024; fka KaloBios; Emerged from Bankruptcy, Jul 2016 |
| deepCDR Biologics | , | Acquired by Alloy Therapeutics, Dec 2021 |
| Antibody Analytics | , | Renamed Rouken Bio, Oct 2024 |
| GATT Technologies | , | Acquired by Ethicon, May 2022 |
| Primal Therapies | , | Website down Dec 2022 - Apr 2023 |
| BAG Diagnostics | Lich, Germany | In-Vitro Diagnostics |
| Charles River Laboratories | Ballina, Ireland | Research Animal Models and Preclinical Research |
| Novartis | Emeryville, CA | Diagnostics |
| Greppo Technologies | , | Renamed Verix Health |
| Cydan Development | , | Shut down Sep 2021 |
| Neuvogen | San Diego, CA | Whole-cell Cancer Vaccines |
| Nucleus Therapeutics | , | Acquired by Patrys, Aug 2016 |
| CytoSeek | , | Renamed Hone Bio, Nov 2024 |
| Genetics Institute | , | Bought by Wyeth, Sep 1996 |
| , | Technically active Jan 2026, but no news since 2011; Residential Address, Jul 2025; Website not fully working Mar 2025 | |
| OXT Therapeutics | , | Seems gone Dec 2020; Single-person company?, Dec 2019 |
| Idorsia | Allschwil, Switzerland | Small Molecules |
| GemPharmatech | San Diego, CA | Genetically Engineered Mouse Models |
| Valsphere | , | Website gone Nov 2019 |
| Foghorn Therapeutics | Cambridge, MA | Cancer Drug Discovery, Protein Degradation |
| Cara Therapeutics | , | Acquired by Tvardi, Apr 2025 |
| Novotech | Taipei, Taiwan | Clinical Research |
| Pro-Dex | Irvine, CA | Device Contract Manufacturing |
| CadheRx Therapeutics | , | Folded Apr 2017 |
| Recipharm | Brescia, Italy | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Sirtris Pharmaceuticals | , | Acquired by GSK Apr 2008, Subsumed Mar 2013 |
| AptamiR Therapeutics | , | Employees all gone except CEO, Apr 2022 |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Formulatrix | Bedford, MA | Lab Automation |
| Heraeus Medical | Houthalen, Belgium | Medical Devices |
| JUVIC | Seoul, Korea | Microneedle Technology |
| Refreshgene Therapeutics | , | Gene Therapy for Hearing |
| Advalytix | , | Acquired by Beckman Coulter, 2009 |
| Heraeus Medical | Karlstein , Germany | Medical Devices |
| |
Skopje, North Macedonia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Ixaka | , | Administration, Aug 2023; fka Rexgenero |
| SIRGA Advanced Biopharma | , | Appears defunct |
| Zosano Pharma | , | Acquired by Emergex out of Chapter 11 bankruptcy Aug 2022, $1M |
| Sunny BioDiscovery | , | Technically active Sep 2019, but website looks like it was pieced together as a Frankenstein website. |
| Azano Biotech | , | Now Sandia Biotech |
| MOMA Therapeutics | Cambridge, MA | Enzymes - Molecular Machines |
| LKC Technologies | Germantown, MD | Electrophysiology Systems |
| Sipra Labs | Hyderabad, India | Product design, Development, Testing, Validation |
| Aspen Pharmacare | East London, South Africa | Small Molecules |
| BRI Biopharmaceutical Research | , | Acquired by Frontage, Dec 2019 |
| Trimb Healthcare | , | Acquired by Karo Pharma, Sep 2019 |
| 3DBiopsy | , | Renamed Triopsy |
| IRIS International | , | Acquired by Danaher, Sep 2012 |
| Olpha | Olaine, Latvia | APIS, Intermediates |
| Pdx Pharmaceuticals | Portland, OR | Nanoparticle Platform for drug delivery |
| Genomic Solutions | , | Acquired by Digilab |
| Microbiome Insights | Richmond, BC | Microbiome Analysis and Research |
| Miltenyi Biotec | San Diego, CA | Magnetic Cell Sorting Products |
| AiRNA Pharmaceuticals | , | No evidence of it ever legally being a business in MA, no website, no news since 2008 |
| , | Website down Oct 2025 - Feb 2026 | |
| ApoVax | , | Shut down Jul 2014 |
| AcuFocus | , | Acquired by Bausch + Lomb, Jan 2023 |
| Ipsen | Dublin, Ireland | Small Molecules |
| BioGenex | Fremont, CA | Cellular & Molecular Diagnostics, Biotech Reagents |
| Boca Pharmacal | , | Bought by Qualitest |
| ClearLight Biotechnologies | , | Stopped Offering Service Dec 2022; fka ClearLight Diagnostics |
| Cinfa Biotech | , | Acquired by Mundipharma, Oct 2018 |
| BioPlx | , | Website down Jun 2023 - Dec 2023 |
| DICE Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $2.4B; fka DiCE Molecules |
| Yecuris | Tualatin, OR | Murine-Derived Hepatocytes |
| Nido Surgical | , | Shut down Apr 2022 |
| NAMSA | Minneapolis, MN | Medical Research Organization - Medical Devices |
| Primatope Therapeutics | , | Acquired by Kiniksa, May 2019 |
| Idenix Pharmaceuticals | , | Bought by Merck, Jun 2014 |
| Progen Pharmaceuticals | , | Acquired by TBG Diagnostics, Jan 2016, Drug sold off to Zucero Therapeutics Aug 2016 |
| Cancer Advances | , | Website down Jan 2022 - Jul 2022 |
| Kymera Therapeutics | Watertown, MA | Small Molecules acting to degrade proteins |
| ValSource | Downingtown, PA | Life Sciences Strategy Consulting |
| , | Renamed Ethyreal Bio, Aug 2024 | |
| Pliant Therapeutics | South SF, CA | Treatments for fibrotic diseases |
| Perimeter Medical Imaging AI | Dallas, TX | Cancer Surgical Margin Identification |
| Handa Pharmaceuticals | San Jose, CA | Specialty pharmaceutical development - generic and 505(b)(2) |
| Metavant Sciences | , | Website down Aug 2022; Sole asset failed Nov 2020; Mar 2018 Roivant spinout |
| C2 Medical Robotics | , | Shut down Aug 2024 |
| 4C Biotech | , | Acquired by Henogen, Jul 2003 |
| Arytha Biosciences | San Diego, CA | Biomimetic Nanoparticles |
| Surface Pharmaceuticals | , | Renamed Surface Ophthalmics, 2021 |
| GlyTR Therapeutics | , | CA business filings late, Jan 2022 - Oct 2025 |
| Apharm | , | Now Biofarma Group |
| Antion Biosciences | Plan-les-Ouates, Switzerland | Gene & Cell Therapy |
| Spryte Medical | Bedford, MA | Neuro Intravascular Imaging Agent |
| Sanofi | North York, ON | Biologics, Vaccines |
| Edding | Shanghai, China | Bringing medicines to Chinese market |
| Mimosa Diagnostics | Toronto, ON | Mobile Health Platform |
| Allist Pharmaceuticals | Shanghai, China | Copycats of American Drugs |
| Velocity Sciences | , | Website down Mar 2025 - Aug 2025 |
| Scholar Rock | Cambridge, MA | Biologics |
| Hana Biosciences | , | Now Talon Therapeutics |
| Fortrea | Durham, NC | Clinical Research |
| Invictech | , | Website down Jun 2022 - Aug 2022 |
| Discuva | , | Acquired by Summit Therapeutics, Dec 2017, £10M |
| |
Albuquerque, NM | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| ImmunoBiochem | , | No news 2018 -2023 |
| RaySearch Laboratories | Stockholm, Sweden | Cancer Research Software |
| Matterworks | Somerville, MA | AI Analysis of Biological Data |
| 4Tech | , | Website down Dec 2020 - May 2021 |
| Fesarius Therapeutics | New York, NY | Engineered tissue products based on IP for microsphere-containing hydrogels |
| T7 Therapeutics | , | No info, Nov 2021 - Jul 2024 |
| InVivo Biosystems | Murray, UT | Devices, consumables, and software for worm screening and phenotyping |
| Zyomyx | , | Closed as of 2014 |
| Biodeal Pharmaceuticals | Noida, India | Generics |
| IntraDiagnostics | , | Dissolved, Jul 2016 |
| Delova Biotech | Nanjing, China | Small molecule analgesics |
| Berkeley Lights | , | Renamed PhenomeX, Mar 2023 |
| R-Biopharm | Darmstadt, Germany | Clinical Diagnostics |
| Hager Biosciences | , | No news since 2011 as of Dec 2020, presumed gone |
| Trilations | Kontich, Belgium | Strategic Consulting |
| Ambu | Ballerup, Denmark | Medical Devices |
| Sanofi | Copenhagen, Denmark | Small Molecules, Biologics |
| In Vitro ADMET Laboratories | , | Acquired by Discovery Life Sciences, Dec 2021 |
| Biointron | Taizhou, China | Antibodies, CRO specializing in antibody discovery, expression, and optimization services for biotech and pharmaceutical companies |
| preclinics | Bruchhausen-Vilsen, Germany | Contract Research |
| Actuate Therapeutics | Fort Worth, TX | Small Molecules for Oncology |
| CANbridge Life Sciences | , | Renamed Canbridge Pharmaceuticals |
| Twinpig Biolab | Seoul, Korea | Immuno-Oncology |
| Tychan | , | Liquidated early 2022 |
| BridGene Biosciences | San Jose, CA | Small molecules that drug traditionally undruggable targets |
| SOV Therapeutics | , | Renamed Marius Pharmaceuticals, Dec 2016 |
| Medgenics | , | Changed name to Aevi Genetic Medicine, Dec 2016 |
| Replimune | Woburn, MA | Oncolytic immunotherapy |
| Raybow USA | Brevard, NC | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| AdvantaPure | Southampton, PA | Tubing, Hose Assemblies |
| Candid Therapeutics | San Diego, CA | Antibodies for Autoimmune Diseases |
| Rentschler Biopharma | Milford, MA | Biologics CMO |
| EchoPixel | San Jose, CA | 3D Surgical Imaging |
| Reata Pharmaceuticals | , | Acquired by Biogen, Sep 2023, $7.3B |
| BioNanovations | , | Website down Jul 2022 - Oct 2022 |
| NanoTess | Calgary, AB | Biocatalysts |
| Phytera | , | Assets sold to Galileo, Apr 2002 |
| Chugai Pharma | Berkeley Heights, NJ | Small Molecules |
| MedTrials | Dallas, TX | Clinical Trial Management |
| Canthera Discovery | Melbourne, Australia | Small Molecule Discovery (oncology) |
| MicuRx Pharmaceuticals | Shanghai, China | Antibiotics |
| Vygon | Ecouen, France | Medical & Surgical Equipment |
| Trinity Laboratories | , | Renamed Torrent Pharmaceuticals |
| Qx Therapeutics | New Haven, CT | MAP3K2/3 inhibitor |
| CMD Bioscience | , | Closed, 2015 |
| GL Technologies | San Diego, CA | Calibration Services |
| Wellesley Pharmaceuticals | , | Seems inactive Aug 2022 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Walk Vascular | , | Acquired by Abbott, Sep 2021 |
| Auspex Pharmaceuticals | , | Bought by Teva Mar 2015, $3.2B |
| ProteinSimple | , | Bought by biotechne, Aug 2014, $300M |
| Satoris | , | Bought by Rules-Based Medicine |
| Dina Pharmaceuticals | , | Preclinical for 8 years, website not working Jun 2020 - Nov 2020; fka Eboo Pharmaceuticals |
| Medeor | , | Acquired by Relmada Therapeutics, Dec 2013 |
| 3P Innovation | Warwickshire, UK | Pharmaceutical Equipment & Automation |
| Satellos Bioscience | Toronto, ON | Stimulating the body’s innate tissue repair and regeneration mechanisms with biologic and small molecule drugs |
| SpecialTeam | , | Assets Acquired by Desco, Dec 2013 |
| Mabwell Biotech | Shanghai, China | Monoclonal Antibodies |
| Rubicon Genomics | , | Acquired by Takara, Jan 2017 |
| Talus Bioscience | Seattle, WA | Gene regulator profiling in live cells for drug development |
| Regain Therapeutics | , | Website down Dec 2021 - Jul 2022 |
| Biochrom GmbH | , | Bought by Millipore, Nov 2012 |
| Moog Medical Devices Group | Salt Lake City, UT | Infusion Pumps |
| Covagen | , | Acquired by Janssen Pharmaceutical, Aug 2014 |
| TRx Pharmaceuticals | , | Acquired by Cerecor, Nov 2017 |
| Origimm Biotechnology | , | Acquired by Sanofi, Dec 2021 |
| Kona Medical | , | Closed, Dec 2016 |
| Exiqon | , | Acquired by Qiagen, Oct 2017 |
| Contineum Therapeutics | San Diego, CA | Small Molecule for MS |
| Aganitha | Hyderabad, India | In Silico Drug Discovery |
| Activ Surgical | Boston, MA | Surgical Software |
| Heart Metabolics | , | Website gone, Apr 2018, company dissolved Apr 2019 |
| Mayflower Bioscience | St. Louis, MO | Life science research products |
| Nodality | , | Gone |
| TeVido BioDevices | , | Website gone May 2024 - Jul 2024 |
| Calporta Therapeutics | , | Acquired by Merck, Nov 2019, $576M |
| Alpharmagen | , | CoMentis/Anvyl co-creation to work on a drugs, seems gone |
| Elutia | Gaithersburg, MD | Drug-eluting biomatrix |
| Schuster Medical Research Institute | , | Not a registered business in CA |
| Orexo | Uppsala, Sweden | Improved specialty pharmaceuticals and treatments for new areas of use |
| Biofourmis | Singapore , Singapore | AI for adverse event prediction |
| Arkios Biodevelopment | , | Business registration canceled in VA |
| Provenance Biopharmaceuticals | , | Licensed drug rights to Alopexx. Shell company |
| Eukarys | Evry , France | Expression system for synthesis of mRNA |
| Sichuan Haisco Pharmaceutical | Chengdu, China | Generics, Small Molecules. Monoclonal Antibodies |
| Antivirals Inc. | , | Renamed AVI BioPharma, Sep 1998 |
| Nexova Biosciences | San Diego, CA | Custom antibodies, Sanger and nanopore sequencing, histopathology and in-vivo studies |
| Redpin Therapeutics | , | Website down Feb 2023 - Jul 2023; Acquired by Kriya Therapeutics, Nov 2022 |
| Certus | , | Website down Apr 2025 - Sep 2025 |
| Northway Biotech | Waltham, MA | Contract research |
| Cogen Immune Therapies | , | Merged with Torque Therapeutics to become Reprtoire Immune Medicines, Mar 2020 |
| Gene ID inc | , | Website taken over |
| Avia Biosystems | , | Acquired by Unchained Labs, Jun 2015 |
| RapidAI | Menlo Park, CA | CT & MRI blood flow visualization |
| Epiva Biosciences | , | Merged into Evelo Biosciences, Jul 2016 |
| UmanDiagnostics | , | Acquired by Quanterix, Jun 2019, $16M cash+$6.5M stock |
| CycloLab | Budapest, Hungary | Cyclodextrin Technology |
| , | No news 2019 - Sep 2025 | |
| Bio Processing | , | Bought by Bio-rad |
| |
Kuala Lumpur, Malaysia | iNGENu CRO | The FDA-centric CRO HQ’ed in Australia, with global offices (Asia, UK, EU, USA). Delivering high-quality clinical research at a fraction of the cost. |
| Symansis | Timaru, New Zealand | Reagents |
| Getinge | Solna, Sweden | Medical Technology |
| Basis Bioscience | , | Website down Jul 2022 - Sep 2022; Residential address, Oct 2021 |
| Applied Immune Technologies | , | Bought by Adicet Bio, Jan 2016 |
| Metaphore Pharmaceuticals | , | Acquired by ActivBiotics, Jan 2006 |
| YS Biopharma | , | Renamed LakeShore Biopharma, May 2024 |
| ArcherDx | , | Acquired by Invitae, Oct 2020, $1.4B; Spun out of Enzymatics after Qiagen acquired |
| BioMarin Pharmaceutical | Buenos Aires, Argentina | Biologics |
| KinBio | Rehovot, Israel | Complex drugs and biosimilars |
| Bioserenity | Paris, France | Epilepsy Diagnosis |
| Siduma Therapeutics | , | Shut down Apr 2024 |
| Chroma Therapeutics | , | Website down Dec 2017-May 2018 |
| VectivBio | , | Acquired by Ironwood Pharmaceuticals, May 2023, $1B |
| AMEGA Biotech | Santa Fe, Argentina | Contract Biosimilars |
| Biosavita | , | Website down Jul 2022 - Nov 2022 |
| NeuroRx (2) | , | Acquired by Clario, Mar 2025 |
| Second Genome | , | Website down Feb 2024 - Jul 2024 |
| Calidi Biotherapeutics | San Diego, CA | Oncolytic Viruses |
| ConcentRx | , | Renamed BioEclipse Therapeutics, Jun 2017 |
| Integrity Laboratories | Knoxville, TN | Infectious Diagnostics |
| Capten Therapeutics | , | Stopped filing reports, 2017 |
| Vignette Bio | , | Merged with Candid Therapeutics, Sep 2024 |
| Walvax Biotechnology | Kunming, China | Development, manufacturing, and distribution of vaccines and blood products |
| Critical Diagnostics | , | No info since 2013 as of 2021, not registered in CA |
| Altheos | , | Closed |
| Abalos Therapeutics | Düsseldorf, Germany | Viral Immuno-Oncology Treatment |
| Aero Pharmaceuticals | , | Acquired by Cocrystal Pharma, May 2011 |
| Invert | San Francisco, CA | Software product for bioprocess development and scale-up |
| RSSL | Wokingham, UK | Analytical Services |
| Alimera Sciences | , | Acquired by ANI Pharmaceuticals, Sep 2024, $381M |
| Great Bay Bio | Hong Kong, China | AI Bioprocessing Equipment |
| Biocam | Wroclaw, Poland | Capsule Endoscopy |
| Celltrion | Branchburg, NJ | Monoclonal Antibody Biosimilars |
| Vintage Pharmaceuticals | , | Acquired by Apax Partners, Sep 2007, now part of Endo |
| Kos Pharmaceuticals | , | Acquired by Abbott 2006 |
| SpinTech MRI | Birmingham Farms, MI | MRI Diagnosis Software |
| Abbott | Altavista, VA | Nutrition |
| Phaedrus Pharmaceuticals | , | Predecessor of NeXus Therapeutics |
| Ribbon Bio | Vienna, Austria | DNA Synthesis |
| Mucommune | Morrisville, NC | Muco-trapping monoclonal antibodies |
| Nexus Spine | Draper, UT | Spinal Implants |
| Etiologics | , | Merged into Argenta Discovery, Oct 2004 |
| PaxMedica | , | Website down Apr 2025 - Sep 2025 |
| Avaliv Therapeutics | , | Website down Dec 2022 - Apr 2023 |
| Thea Pharma | Waltham, MA | Ophthalmic Therapies |
| RenaMed Biologics | , | Assets sold to Nephrion, 2007 |
| AdvanSource Biomaterials | , | Sold most assets to Mitsubishi Chemical, Jan 2020 |
| EarlyDx | Agoura Hills, CA | Liquid Biopsy |
| CareDx | Brisbane, CA | Diagnostics |
| Takara Bio USA | San Jose, CA | Lab products |
| Kivu Bioscience | San Francisco, CA | ADCs |
| |
Curtis Bay, MD | Grace | Custom engineered silicas, chromatography resins, and multifunctional formulation excipients, tailored to meet your exact specifications. |
| A2IDEA | , | Only employee left Jan 2024 |
| Siegfried | Evionnaz, Switzerland | Contract Drug Manufacturing, APIS, Development |
| Ozette Technologies | Seattle, WA | AI-driven Computational Analysis |
| Stellate Therapeutics | , | Website maintenance, Mar 2023 - Nov 2023, LI page gone Nov 2023 |
| Quest Clinical Research | , | Now part of eStudysite |
| Martindale Pharma | , | Acquired by Ethypharm, Mar 2017 |
| EAG Laboratories | Shanghai, China | Analytical & Synthesis Services |
| VasculoMedics | , | Gone 2019 |
| Trilations | New York, NY | Strategic Consulting |
| NemaMetrix | , | Renamed InVivo Biosystems, Mar 2020 |
| Avineuro | , | Website taken over Feb 2024 |
| KSL Biomedical | Jiangsu, China | Diagnostic Technology |
| Zyoxel | , | Renamed CN Bio, Feb 2014 |
| Incipio Devices | St-Blaise, Switzerland | Orthopedic Devices, Contract Manufacturing |
| Renaissance | Lakewood, NJ | Contract Manufacturing - Nasal Sprays, Sterile Solutions |
| TaiwanBio | , | Website gone Oct 2021 |
| Circularis | , | Acquired by Ginkgo Bioworks, Oct 2022 |
| Kalos Therapeutics | , | Soliciting donations on website, not a nonprofit, dated website |
| Certara | Montréal, QC | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Zymenex | , | Acquired by Chiesi, Aug 2013 |
| Qnova LifeSciences | Columbia, MD | Consulting, Clinical Trial Enrollment |
| Inspirata | Tampa, FL | Cancer Insights |
| Xoran Technologies | Ann Arbor, MI | CT Scanners |
| Almac | Penicuik, UK | Pharmaceutical Services |
| Inverseon | , | Merged with Cbio to become Invion, Aug 2012 |
| Genvion | Winnipeg, MB | Contract Pharma Manufacturing |
| Langhua Pharmaceutical | , | Acquired by Viva Biotech, Aug 2020, $367M |
| Devsynthesis | Barcelona, Spain | Chemistry CRO |
| Imaging Advantage | , | Acquired by Envision Healthcare, Mar 2017 |
| Pinnacle Transplant | Phoenix, AZ | Allografts |
| Prexton Therapeutics | , | Acquired by Lundbeck, Mar 2018, $123M |
| Agenix | , | Gone, Website taken over |
| Hokanson Vascular | Bellevue, WA | Vascular Instruments |
| Cebix | , | Shut down, Feb 2015 |
| Vaccibody | , | Renamed Nykode Therapeutics |
| Kaiser Optical Systems | , | Merged with SpectraSensors to become Endress+Hauser, Jan 2022 |
| BAIT Therapeutics | , | Renamed Kyverna Therapeutics, Oct 2019 |
| |
Carugate, Italy | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| PvP Biologics | , | Bought by Takeda, Feb 2020, up to $330M |
| Absalus | , | Acquired by EvoGenix, Apr 2005 |
| , | Website down Dec 2025 - Apr 2026 | |
| Biochromex | , | Website down Feb 2025 - Jul 2025 |
| Ribozyme Pharmaceuticals | , | Renamed Sirna Therapeutics Apr 2003 |
| Oxford Biomedical Research | Rochester Hills, MI | Assays |
| EpiTherapeutics | , | Bought by Gilead, May 2015, $65M |
| Cellmed Research | , | Website down Feb 2021 - Jul 2021 |
| Techulon | , | Website down Apr 2022 - Aug 2022 |
| Conavi Medical | Toronto, ON | Robotic Surgical Technologies |
| Bioxene | , | Website gone, Company Presumed gone |
| Dynex Technologies | Hong Kong, China | Microplate Readers, Technology |
| Theradex | Princeton, NJ | Oncology Clinical Research |
| Panther Orthopedics | , | Shut down Dec 2022 |
| AGC Biologics | Chiba, Japan | Contract Manufacturing - Biologics |
| Leica Biosystems | Deer Park, IL | Diagnostic Lab Products |
| Bayer | Whippany, NJ | Biotech / Pharma / Chemical Giant |
| Bioceros | , | Bought by Epirus Biopharmaceuticals, Sep 2015, $14M |
| Chronix Biomedical | , | Website down May 2021 - Sep 2021 |
| Parabase Genomics | , | Presumed gone |
| Gangagen | Bangalore , India | Ectolysins |
| Siare Engineering | Crespellano-Valsamoggia, Italy | Mechanical Ventilators |
| Glixis Therapeutics | , | Website taken over Jul 2020 |
| HpVac | , | Renamed Atopia Therapeutics |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| Mousera | , | Renamed Vium |
| Trilations | Tokyo, Japan | Strategic Consulting |
| Molsid | Lyon, France | Fluorogenic Probes |
| Exela Pharma Sciences | Lenoir, NC | Contract manufacturing - injectable, ophthalmic, inhalation solutions that are internally developed |
| Decoy Biosystems | , | Merged with Intec to become Indaptus Therapeutics, Aug 2021 |
| Aracari Biosciences | Irvine, CA | Vascularized Tissues that mimic the Human Body |
| |
South Haven, MI | Grace Fine Chemical Manufacturing Services | CDMO with capabilities to support your next small molecule drug project, including custom APIs, RSMs, and intermediates. Network of 2 integrated U.S.-based sites with capacity from the lab to commercial-scale production. |
| Alentis Therapeutics | Allschwil, Switzerland | Monoclonal Antibody |
| ChiRhoClin | Burtonsville, MD | Orphan diagnostics |
| Siva Therapeutics | , | Acquired by Sona Nanotech, Mar 2023, $2M + $6.65M milestones |
| Inovio Pharmaceuticals | Plymouth Meeting, PA | DNA Vaccines |
| Phase Genomics | Seattle, WA | Microbial Genome Identification |
| Cuprous Pharmaceuticals | , | Website down Nov 2022 - Mar 2023 |
| Antibiotice | Iasi, Romania | Generics |
| PanThera Bio | Lancashire, UK | Site Management Organization |
| Rosemont Pharmaceuticals | Leeds, UK | Liquid Medicines |
| Ethris | Planegg, Germany | MRNA-based therapies, vaccines |
| Luceome Biotechnologies | Tucson, AZ | Assay technology for identification of drugs against kinases |
| NewVac | , | |
| General Regeneratives | , | Website down Oct 2020 - Feb 2021 |
| ACS DOBFAR | Tribiano, Italy | Contract Generics & APIs |
| , | Selling pipeline, winding down Jul 2025 | |
| Acumen Pharmaceuticals | Charlottesville, VA | Alzheimer’s targeting antibody |
| Ivenix | , | Acquired by Fresenius Kabi, May 2022, $240M + milestones |
| PharmCADD | Seoul, Korea | AI Drug Development Platform |
| Oxitone Medical | Kfar Saba, Israel | Wearable pulse oximetry device |
| Ampersand Biomedicines | Boston, MA | AND-Body Therapeutics |
| Tiger X Medical | , | Merged into BioCardia, Aug 2016 |
| Vapotherm | Exeter , NH | Respiratory Therapy Devices |
| Hamamatsu Pharma Research | , | Acquired by CMIC, Oct 2023 |
| , | ||
| Déclion Pharmaceuticals | , | Website gone Nov 2019 - Dec 2020 |
| PharmaFluidics | , | Acquired by Thermo Fisher, Oct 2021 |
| Surrozen | South SF, CA | Wnt signaling antibodies |
| Phasiq | , | Website gone Jul 2018 |
| Immunome | Exton, PA | Cancer Immunotherapy |
| NIOX | Morrisville, NC | Asthma management device |
| Prevacus | , | Website down Jul 2021 - Dec 2021 |
| Effimune | , | Merged with OSE Pharma, May 2016, renamed OSE Immunotherapeutics |
| Complete Genomics | San Jose, CA | Genomic Studies |
| Volta Labs | Boston, MA | Genomic Sample Prep Technology |
| ApopLogic Pharmaceuticals | , | Gone 2014 |
| MethodSense | Morrisville, NC | Medical device quality and regulatory consulting |
| Highline Sciences | , | Acquired by Tempus, Feb 2022 |
| Brabant Pharma | , | Acquired by Zogenix, Oct 2014, $20M cash, $15M stock |
| Mazor Robotics | , | Acquired by Medtronic, Dec 2018, $1.7B |
| BioParadox | , | Shut down Dec 2017 |
| CURx Pharmaceuticals | , | No business filings since 2020 as of Jul 2022 |
| Leadiant Biosciences | Rockville, MD | Orphan Disease Treatments |
| Aeirtec | Newcastle upon Tyne, UK | Biomarkers, Biostatistics, Gene Expression |
| ALR Technologies | Richmond, VA | App for tracking blood glucose results |
| ForSight VISION5 | , | Acquired by Allergan, Aug 2016, $95M |
| Azura Ophthalmics | Tel Aviv, Israel | Ophthalmic keratolytics |
| Endothelix | , | Now owned by American Heart technologies |
| , | Website down Jul 2025 - Dec 2025 | |
| Aeson Therapeutics | , | Gone Mar 2006 |
| Medtronic | Warsaw, IN | Medical Devices |
| Viridus Animal Health | , | Bought by Huvepharma, Mar 2014 |
| CG Oncology | Irvine, CA | Oncolytic Virus |
| CNCure Biotech | Hwasun-gun, Korea | Bacterial Platform for Developing Treatments, Radiotheranostics |
| Admera Health | South Plainfield, NJ | Genetic Diagnostics |
| Zevra Therapeutics | Frederiksberg, Denmark | Modifications of Existing Drugs |
| Trogen Biotechnologies | , | Renamed Epeius Biotechnologies, May 2001 |
| SL Pharma Labs | , | Website gone May 2018 |
| SPES Pharmaceuticals | Plainsboro, NJ | 505 b(2) Small Molecules |
| PCI Pharma Services | Moorabbin Airport, Australia | Contract Manufacturing, Services |
| Procyon Biopharma | , | Merged with Cellpep to become Ambrilia Biopharma, Jan 2006 |
| MiddleBrook Pharmaceuticals | , | Bought by Victory Pharmaceuticals 2011 |
| Elucid Bio | , | Renamed Elucid, Jan 2022 |
| Agno Pharma | Eugene, OR | Small molecule CRO, CDMO |
| Renovo Neural | , | Website Under Construction Dec 2019 - Oct 2020 |
| Carticept Medical | , | Dissolved Feb 2020 |
| Accellacare | Cary, NC | Clinical Research |
| Ascent Therapeutics | , | Changed name to Anchor Therapeutics, Feb 2010 |
| Salipro Biotech | Stockholm, Sweden | Membrane Protein Stabilization Technology |
| Aristos Pharmaceuticals | , | Owned by Cornerstone Therapeutics |
| Antibody Systems | , | Presumed defunct, Jan 2023; website copyright 2012 |
| Illuminant Surgical | Culver City, CA | Surgical Visualization |
| Vandalia Research | , | Assets acquired by Applied DNA Sciences, $1.5M, Sep 2015 |
| Scendia Biologics | , | Acquired by Sanara MedTech |
| MindWalk | Victoria, BC | Custom Antibodies |
| DWK Life Sciences | Millville, NJ | Lab Equipment |
| RXi Pharmaceuticals | , | Renamed Phio Pharmaceuticals, Nov 2018 |
| NeuWave Medical | , | Bought by Ethicon, Mar 2016 |
| NeoGenesis Pharmaceuticals | , | Assets acquired by Schering-Plough, Jan 2005 |
| Amphioxus Cell Technologies | , | Marked as closed on Google Aug 2021; no info, no website Feb 2019 - Aug 2020 |
| Epinex Diagnostics | Irvine, CA | Diabetes Diagnostic |
| Innervo Technology | , | Website down Jul 2023 - Dec 2023 |
| EurekaBio | Shenzhen, China | Lentiviral Vector Production System |
| Integer | Alden, NY | Medical & Surgical Devices |
| DC Devices | , | Changed name to Corvia Medical Jun 2015 |
| Novo Biosciences | , | Website down Sep 2021 - Jan 2022 |
| BigDNA | , | Renamed Icemi Pharmaceutical, May 2016 |
| Quintessence Bioscience | , | Dormant Jan 2017, Employees gone |
| Gen Pharmaceuticals | Ankara, Turkey | Small Molecules |
| SpringLeaf Therapeutics | , | Closed Mar 2013, technology may have segued into scPharmaceuticals |
| Hematogenix | Tinley Park, IL | Pharma Services |
| DNAVEC | , | Renamed ID Pharma, Apr 2015 |
| PeptiDream | Tokyo, Japan | Peptide generation platform |
| Vanadis Diagnostics | , | Bought by PerkinElmer, Jan 2016 |
| CellBios Healthcare & Lifesciences | Chennai, India | Blood Products, Bioprocess Equipment |
| SonaCare Medical | , | Renamed Sonablate, Jul 2021 |
| Anaconda Pharma | , | Acquired by Biota, Feb 2015 |
| BioMedicure | , | Business lapsed in CA, website last updated 2010 |
| Iconovo | Lund, Sweden | Inhalation Technology |
| ColonaryConcepts | , | Website down Jul 2025; Residential address |
| RFE Pharma | , | Gone 2019 |
| Longevity Biotech | Philadelphia, PA | Synthetic Peptides |
| CartiHeal | , | Acquired by Smith + Nephew, Jan 2024; Acquired by Bioventus, Jul 2022, $315M+ |
| ProMIS Neurosciences | Cambridge, MA | Neurodegenerative Therapies |
| IBT Bioservices | Rockville, MD | Reagents for viral, bacterial research, antibody production |
| Realm Therapeutics | , | Acquired by ESSA Pharma, Jul 2019; fka PuriCore, abandoned all clinical work Sep 2018, seems to be wound care/topical 510(k) products |
| Mitra Biotech | , | Renamed Farcast Biosciences, 2019 |
| Anthera Pharmaceuticals | , | Still publicly traded, almost worthless, Website down Mar 2020 - Oct 2020 |
| , | Insolvent, Website down Nov 2025 - Feb 2026 | |
| Biosynth | Compton, UK | Staad Chemicals contract manufacturing / research. Carbohydrates, nucleosides, APIs & enzyme substrates |
| Exegenesis Bio | Lexington, MA | Gene Therapy |
| Curon Biopharmaceutical | , | Asset acquired by Merck, Aug 2024 |
| ADARx Pharmaceuticals | San Diego, CA | RNA Therapeutics |
| Custom Biologics | Toronto, ON | Large and Small Molecule Contract Research |
| Microbiotix | Worcester, MA | Small Molecules |
| HistologiX | Nottingham, UK | Cellular and Digital Pathology |
| Amedis Pharmaceuticals | , | Acquired by Takeda, Jan 2005 |
| Tergus Pharma | , | Merged with MedPharm, Jul 2024 |
| Jubilant Radiopharmacies | Yardley, PA | Radiopharmaceuticals |
| ARKAY Therapeutics | , | No info 2019- Oct 2023 |
| Synaptrix | New York, NY | Brain-Computer Interface |
| Stempeutics Research | Bangalore , India | Stem Cell Therapeutics |
| Charles River Laboratories | Ahmedabad, India | Research Animal Models and Preclinical Research |
| Callisyn Phamaceuticals | , | Closed Feb 2005 |
| , | Merged with Nova Biomedical | |
| Javara | Winston-Salem, NC | Embedded Clinical Research |
| Basecamp Research | London, UK | AI-Biology Data |
| Revolve Biotechnologies | , | Founder has another job, no employees listed on website |
| Biognosys | Schlieren, Switzerland | Protein quantification technology, contract protein analysis |
| Antengene | Shanghai, China | Small Molecules, Monoclonal Antibodies, Bispecifics |
| CAMP4 Therapeutics | Cambridge, MA | RNA Amplified Therapeutics |
| Merit Medical | South Jordan, UT | Numerous Medical Devices |
| Eleven P15 | , | Shut down |
| Avanos Medical | Zavantem, Belgium | Pain Management, Respiratory, IV Devices |
| Inscopix | Mountain View, CA | Miniature Microscope |
| Novotech | Auckland , New Zealand | Clinical Research |
| Integrated Genomics | , | Changed to Igenbio |
| Ampio Pharmaceuticals | , | Dissolved Aug 2024 |
| Reset Pharmaceuticals | Great Neck, NY | Psilocybin |
| Clementia Pharmaceuticals | , | Bought by Ipsen, Apr 2019, $1.31B |
| Oncogenuity | Bay Harbor Islands, FL | Oligonucleotide platform for the treatment of genetically driven cancers |
| Living Pharma | , | Acquired by Lentigen, Jul 2017 |
| Tranquil Clinical Research | Webster, TX | Clinical Research |
| Trimeris | , | Merged with Synageva |
| Proteros Biostructures | Planegg, Germany | Chemical Structural Analysis |
| Serena Group | Cambridge, MA | Wound care and hyperbaric oxygen therapies |
| Hepta | San Francisco, CA | Liquid Biopsy |
| Immunex | , | Bought by Amgen, Jul 2002, $16B |
| Pierre Fabre | Castres, France | Oncology, derm / cosmetics |
| Alseres Pharmaceuticals | , | Ceased Operations, presumably ran out of cash; fka Boston Life Sciences |
| Rich Pharmaceuticals | , | Basically Gone Apr 2019 |
| VCN Biosciences | , | Acquired by Synthetic Biologics, Mar 2022 |
| Malvern Panalytical | Malvern, UK | Preclinical CRO |
| Arena Pharmaceuticals | , | Acquired by Pfizer, Dec 2021, $6.7B |
| EmerVax | , | Renamed Circurna |
| Cerimon | , | Gone |
| GemacBio | , | Renamed PolyNeuroS |
| DAYSAI BIOPHARMACEUTICALS | , | No info. SBIR 2013 |
| BA Sciences | Morrisville, NC | Analytical Services |
| AmacaThera | Toronto, ON | Hydrogel-based drug delivery |
| Nexcelom Bioscience | , | Acquired by PerkinElmer, May 2021, $260M |
| HEC | , | Website down Dec 2024 - May 2025 |
| Piramal | Digwal, India | CDMO |
| Pivot Medical | , | Bought by Stryker, Mar 2014 |
| joimax | Karlsruhe, Germany | Endoscopic Minimally Invasive Spinal Surgery |
| OrthoPediatrics | Warsaw, IN | Pediatric Orthopedic Implants |
| Spartina Biotechnologies | , | Renamed Mercury Bio, Mar 2023 |
| , | Liquidated, Jun 2025; Bought by Terumo, Jul 2020, $20M + $2M Milestones | |
| TamRx | , | Website taken over Aug 2020 |
| Singlera Genomics | , | Website down Dec 2023 - May 2024 |
| Immunitrack | , | Acquired by Eli Lilly, Oct 2023 |
| |
Philadelphia, PA | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Abbott | Pleasanton, CA | Implantable heart pumps for heart failure |
| 3PBIOVIAN | Navarra, Spain | Contract Development & Manufacturing |
| Actium Biosystems | , | Gone 2013 |
| Coté Orphan | , | Acquired by Quintiles, Jun 2017 |
| Valeo Pharmaceuticals | Kirkland, QC | Small Molecules |
| Aracea Therapeutics | , | No website Aug 2022 |
| YARAL Pharma | Parsippany, NJ | Generics, 505(b)(2) |
| ImpediMed | Pinkenba, Australia | Bioimpedance spectroscopy devices for use in the non-invasive clinical assessment and monitoring of tissue composition and fluid status |
| Getinge | Mahwah, NJ | Medical Technology |
| Adlyfe | , | Gone, no info |
| , | Website down Dec 2025 - Apr 2026 | |
| Paige | New York, NY | AI Pathology |
| Resonetics | Puidoux , Switzerland | Contract Medical Device Manufacturing & Development |
| Celexion | , | Gone Jul 2015, some assets acquired by Agenus |
| Celprogen | Torrance, CA | Stem cell research and therapeutics products for regenerative medicine |
| Mitosciences | , | Acquired by Abcam, May 2011, $6M |
| Kyron.bio | Paris, France | N-glycosylation of Antibody Therapeutics |
| Myriad Proteomics | , | Changed name to Prolexys Pharmaceuticals |
| Spherium Biomed | , | Est 2013, No website Jan 2020 |
| Avitus Orthopaedics | , | Acquired by Zimmer Biomet, Mar 2025 |
| Ra Pharmaceuticals | , | Bought by UCB, Apr 2020, $2.1B |
| PSMA Therapeutics | , | Acquired by Bayer, Jun 2021 |
| Resonetics | Blaine, MN | Contract Medical Device Manufacturing & Development |
| Quanticate | Raleigh, NC | Clinical Research |
| BioBehavioral Diagnostics Company | , | Assets acquired by Pearson, Aug 2013 |
| Celerion | Belfast, UK | Clinical Research |
| PharmaClean Group | , | Website gone, Sept-Nov 2018 |
| Espero Biopharma | , | Website down Oct 2021 - Mar 2022 |
| Alliance Contract Pharma | , | Acquired by Altasciences, Feb 2020 |
| Marical | , | Website Gone |
| Heragen | , | Gone |
| Qu Biologics | Burnaby, BC | Site Specific Immunomodulators |
| Curevax | , | Website not working Apr 2021 - Aug 2021 |
| Oscine Therapeutics | , | Acquired by Sana Biotechnology, Oct 2020 |
| Defensin Therapeutics | , | Website down Feb 2024 - Jul 2024 |
| Great Lakes Pharmaceuticals | , | Disappeared, no info |
| Indago | , | Renamed Lazurite |
| Kiniksa Pharmaceuticals | Lexington, MA | Biologics, Monoclonal Antibodies |
| |
Wuppertal, Germany | WuXi Biologics - global CRDMO contract services, integrated or standalone, mammalian & microbial expression supports full range of biologic modalities |
| IQVIA | Durham, NC | Clinical Research |
| Kleo Pharmaceuticals | , | Acquired by Biohaven, Jan 2021 |
| Musculoskeletal Clinical Regulatory Advisers | Washington, DC | Clinical Research Consulting |
| Singapore Advanced Biologics | , | Dated website, no employee on LI Feb 2025, no news 2022-2025 |
| CrossRoads Extremity Systems | , | Acquired by DePuy, Feb 2022 |
| XENSE | Irvine, CA | AI-enabled CT and X-ray imaging tech |
| SBH Sciences | Natick, MA | A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. |
| Next Generation Clinical Research | , | Website down Dec 2024 - May 2025 |
| Medisun Precision Medicine | , | Gone by 2019; fka Accurexa |
| NunaBio | Newcastle upon Tyne, UK | Synthetic DNA Constructs |
| Myogen | , | Acquired by Gilead, Oct 2006, $2.5B |
| Sinfonia Biotherapeutics | , | Website down Jan 2025 - Jul 2025 |
| Patheon | Durham, NC | Contract Manufacturing and Development |
| Amorfix Life Sciences | , | Renamed ProMIS Neurosciences, Jul 2015 |
| FiberCell Systems | New Market, MD | Cell Growth Systems |
| Blue Stream Laboratories | , | Acquired by Charles River, Jun 2016 |
| Avedro | , | Acquired by Glaukos, Nov 2019 |
| TRPblue | , | Shut down Dec 2023 |
| LC Technologies | , | Renamed EyeGaze |
| CAGE Bio | San Carlos, CA | Deep Eutectic Ionic Liquids for Therapeutics |
| AH Diagnostics | Tilst, Denmark | Diagnostics |
| AbbVie | Singapore, Singapore | Small Molecules, injectables |
| siTools Biotech | Planegg-Martinsried, Germany | Reagents for RNA interference |
| Fulgent Genetics | El Monte, CA | Next-gen Sequencing |
| , | Shut down Jan 2026 | |
| Qualicaps | Whitsett, NC | Capsules |
| Lucira Health | , | Assets acquired out of Chapter 11 Bankruptcy by Pfizer, Apr 2023, $36.4M; fka Diassess |
| |
Largo, FL | Formulated Solutions develops and manufactures topical, liquid, aerosol, and nasal drugs—supporting partners from clinical to full-scale launch |
| , | No business filings in MA Nov 2023 - Jun 2026; Residential address Sep 2019 | |
| ReproSource | Marlborough, MA | Fertility Testing |
| ARTIRIA Medical | Geneva, Switzerland | Neurovascular Guidewire |
| Aralez Pharmaceuticals | , | Bankrupt, Aug 2018, selling all assets |
| Kashiv Pharma | , | Renamed Kashiv BioSciences, Jan 2019 |
| SK Biotek | , | part of SK pharmteco |
| Helus Pharma | Toronto, ON | Psychedelics |
| Equilibre Biopharmaceuticals | , | Website down Aug 2023 - Jan 2024 |
| Trajan Group | Ringwood, Australia | Chromatography and Mass Spec technology |
| Cellaria Biosciences | , | Website down Aug 2023 - Feb 2024 |
| Minerva Surgical | Santa Clara, CA | Endometrial Ablation System |
| DeNovaMed | , | Website down Oct 2022 - Mar 2023 |
| Gyrus Pharmaceuticals | , | Shut down Aug 2019 |
| Velia Therapeutics | , | Shut down Jan 2025 |
| AmCell Biosciences | , | Website gone Apr 2021 |
| Briteseed | Chicago, IL | Blood Vessel-Detecting Surgical Snips |
| , | Assets being sold off May 2026 | |
| Modular Bioscience | , | Seems gone Jun 2022 |
| Cilian | , | Website down Jul 2024 - Dec 2024 |
| Pure Biologics | Wroclaw, Poland | Biologics, Devices, Diagnostics |
| VitalMED | , | Acquired by Kelpac, Jan 2016 |
| Nanostim | , | Acquired by St. Jude Medical, Octo 2013 |
| Tisucor | , | Shut down Feb 2020 |
| BenevolentAI | London, UK | AI technologies for drug discovery and development |
| Theranostech | , | Renamed Sandia Biotech |
| Evelo Therapeutics | , | Now Evelo Biosciences |
| Larimar Therapeutics | Bala Cynwyd, PA | Small Molecules |
| Amorcyte | , | Acquired by Neostem, Oct 2011 |
| Viant Medical | San Antonio, TX | Contract Medical Devices |
| Cell2Cure | Søborg, Denmark | Cell Therapies |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| Palamedrix | , | Acquired by SomaLogic, Jul 2022, $35M |
| Gran Med | , | Gone |
| Biolyse Pharma | , | Website down, claimed they were in danger of going out of business in 2016 |
| JK Biopharma Solutions | , | Founder gone |
| Glialogix | , | Gone Nov 2017 |
| Amresco | , | Acquired by VWR, Feb 2011 |
| Breakthrough Pharma | , | Website down Aug 2023 - Apr 2024 |
| Ariagen | , | Business filings late Aug 2022 - Aug 2024; no info, May 2020 - Aug 2024 |
| iThemba Pharmaceuticals | , | No information |
| Tune Therapeutics | Seattle, WA | Epigenetic modification to modulate gene expression |
| CureGenetics | Suzhou, China | Gene-editing - Diagnostics, Therapies |
| JOINN Biologics | Beijing, China | Biologics CDMO |
| Aixial Group | Villeurbanne, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| AbbVie | Waco, TX | Contract Manufacturing |
| HemaFlo Therapeutics | , | Shut Down Oct 2021; fka DRP Biomedical |
| RRD International | , | Renamed RRD Biopharma Development, Feb 2024 |
| Ion Channel Innovations | , | Primitive website, no apparent employees. Got $1M SBIR grant in 2013 |
| Biotek | , | Acquired by Agilent, Aug 2019 |
| ViVerita Therapeutics | Acton, MA | in vivo screening technology for oncology therapies |
| CMIC | Cranbury, NJ | Pharmaceutical Contract Work |
| Veriton Pharma | Weybridge, UK | Small Molecules, Compounded Formulations |
| Nordmark Biotech | Uetersen, Germany | Contract Manufacturing |
| QuidelOrtho | San Diego, CA | Molecular Diagnostics |
| Pace | Lenexa, KS | Analytical Testing, CDMO |
| M8 Pharmaceuticals | , | Acquired by Acino, Dec 2023 |
| Fulcrum Therapeutics | Cambridge, MA | Unlocking gene control mechanisms to develop small molecule therapies |
| Bohai Pharmaceuticals | , | Bankrupt, 2017 |
| Resonetics | San Diego, CA | Contract Medical Device Manufacturing & Development |
| Alloy Therapeutics | Waltham, MA | Antibody Discovery Platform & Services |
| Abbott | Santa Clara, CA | Drug-Eluting Stents |
| Tmunity Therapeutics | , | Acquired by Kite Pharmaceuticals, Feb 2023 |
| Enoda Cellworks | Menlo Park, CA | Cell Therapy |
| PrognomiQ | San Mateo, CA | Multi-omic Diagnostics |
| Custom Pharma Services | East Sussex, UK | CRO, CDMO |
| Besins Healthcare | Monaco, Monaco | Men's / Women's Health |
| Chong Kun Dang Pharmaceutical | Seodaemun, Korea | Small Molecules |
| Vyteris | , | Bankrupt 2012 |
| Acquist Therapeutics | , | Website down Aug 2023 - Apr 2024; fka Relburn-Metabolomics |
| Virtuoso Therapeutics | San Mateo, CA | Therapeutic Antibodies |
| |
Ghent, Belgium | Eurofins CDMO | APIs/Drug Substance & Drug Product development for biologicals and small molecules |
| Cofactor Genomics | St. Louis, MO | Genomic Analysis |
| Everis Medical | Schoolcraft, MI | Surgical Devices, Compartment Pressure Monitor |
| Novum Clinical Research | , | Now Novum Pharmaceutical Research Services |
| zPREDICTA | , | Acquired by Predictive Oncology, Dec 2021 |
| Alpine Biotherapeutics | , | Website down Jul 2022 - Nov 2022 |
| Aridis Pharmaceuticals | Los Gatos, CA | Monoclonal Antibody & Small Molecule Targeting Infectious Diseases |
| Advena | Warwick, UK | Medical Device Regulatory Consulting |
| Orphan Technologies | , | Acquired by Travere Therapeutics (Retrophin), Nov 2020, $90M + $427 Milestones |
| Greer Laboratories | , | Merged into Stallergenes to become Stallergenes Greer |
| Ra Medical Systems | , | Rebranded as Catheter Precision after Merger |
| Nova-One Diagnostics | , | Website down Mar 2025; Business filings late, Dec 2023 - Mar 2025 |
| OncoRes Medical | Nedlands, Australia | Intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure |
| Drug Farm | Shanghai, China | Using AI to discover genetic therapies |
| Transition Bio | Cambridge, UK | Condensate technology, liquid-liquid phase separation |
| Zeno Pharmaceuticals | , | Website taken over, Sep 2017 |
| Altruist Biologics | Hangzhou, China | Biologics CDMO |
| Owlstone Medical | Cambridge, UK | Breath-based Diagnostics |
| Wyeth | , | Bought by Pfizer |
| Kastle Therapeutics | , | Closed May 2018 |
| GenCell Biosystems | , | Acquired by BD, Oct 2014 |
| Aalto Scientific | Eatonton, GA | Contract Reagents, Proteins |
| Henovcom Bioscience | Guangzhou, China | Small Molecules, mRNA, 505 (b)(2) |
| Pirche | Grünwald, Germany | Transplant Matching |
| Nobel Ilac | , | Website down Dec 2019 - Aug 2020 |
| Octant Biotech | Emeryville, CA | Small Molecules |
| , | Website down Jul 2025 - Jan 2026 | |
| Subtle Medical | Menlo Park, CA | Imaging Software |
| Cellegy Pharmaceuticals | , | Acquired by Adamis, Feb 2008 |
| BMG LABTECH | Ortenberg, Germany | Microplate reader instrumentation |
| NeuroVia | , | Shut down 2019 |
| Regenesis Biomedical | Scottsdale, AZ | Energy-Based Pain Management Devices |
| BioTelemetry | , | Acquired by Philips, Feb 2021; fka CardioNet |
| Vivendo Pharma | Cham, Switzerland | Generics, Biosimilars, Devices |
| Trimel Pharmaceuticals | , | Changed name to Acerus Pharmaceuticals, Sep 2015 |
| Auris AI | , | Website taken over or pivoted, down Nov 2022 |
| Vivodyne | Philadelphia, PA | Lab Grown Organs for Drug Development |
| X-spine | , | Bought by Bacterin, Jul 2015, $73M, combined with Bacterin to become Xtant Medical |
| MaxThera | , | Shut Down Dec 2011 |
| Moore Clinical Research | , | Renamed TrueBlue Clinical Research, Jun 2022 |
| 4baseCare | Bangalore, India | Diagnostics, App-technology |
| Automated Glucose Control | , | Assets acquired by Insulet, Feb 2023 |
| RAUMEDIC | Helmbrechts, Germany | Polymer-based solutions for medical and pharmaceutical applications |
| Tarsus Pharmaceuticals | Irvine, CA | Blepharitis Treatment |
| CenExel Clinical Research | Anaheim, CA | Clinical Research |
| Cytox | , | Website down Apr 2024 - Aug 2024; Initially founded in 2006, re-created in 2013 |
| Andrulis Pharmaceuticals | , | Lost court case to Celgene, Jul 2016, doesn't seem active |
| Novotech | Sydney, Australia | Clinical Research |
| Phyton Biotech | Ahrensburg, Germany | Plant Cell Culture |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| Lacrimedics | , | Acquired by Innovia Medical, Nov 202 |
| Avestin | Mannheim, Germany | Precision High-Pressure Homogenizers & Liposome Extrusion Systems |
| Ilkos Therapeutic | , | Acquired by Odan Laboratories, Dec 2020 |
| Viafet Genomics | , | Website under construction Oct 2021 - Jul 2022 |
| Java Clinical | , | Website gone Jun 2019 |
| American Gene Technologies | Rockville, MD | Gene Therapy and Immunotherapy Company. Lentiviral Vector Platform and Indication-Specific Technologies. Lead Therapeutics for an HIV Cure, Liver Cancer Cure, and PKU therapy |
| Novonesis | North Rocks, Australia | Enzymes |
| Somahlution | , | Acquired by Marizyme, Sep 2020 |
| Hygtia Therapeutics | , | |
| Insys Therapeutics | , | Filed Chapter 11 bankruptcy, Jun 2019, website gone Apr 2020 |
| DMD Therapeutics | , | Gone Nov 2018 |
| Endpoint Health | Palo Alto, CA | Personalized Medicine |
| AntalGenics | Elche-Alicante, Spain | Cosmetics & Services |
| GSK | Weybridge, UK | Small Molecules, Vaccines, Biologics |
| Immedica | , | Renamed Advanced Biomaterial Systems, Jan 2004 |
| Ravel Biotechnology | , | Website down Sep 2023 - Mar 2024 |
| Abingdon Health | York, UK | Lateral flow immunoassay and reader rapid diagnostics contract manufacturing |
| Protein Potential | , | Shut down Mar 2024; Same employees as Sanaria, both got separate SBIR grants totaling $8M |
| Otovia Therapeutics | , | Website down Jan 2025 - Jul 2025 |
| , | Acquired by Mdxhealth, Sep 2025, $15M; Acquired by Bio-techne, Aug 2018, $250M + $325M milestones | |
| FGK Clinical Research | Munich, Germany | Clinical Research |
| Benchmark Biolabs | , | Parent acquired by Huvepharma, Jan 2018 |
| Soterix Medical | Woodbridge, NJ | Neuromodulation |
| Immudicon | , | Moved from San Francisco, sole employee is CEO of new company |
| Global Cell Solutions | , | Gone Apr 2018 |
| Amgen | Juncos, PR | Small Molecules, Biologics |
| Prevacept Infection Control | , | Website down Feb 2021; Did not file 2018 or 2019 annual report |
| ProAxsis | Antrim, Ireland | Detection and measurement of active protease biomarkers |
| Cocoon Bioscience | Madrid, Spain | Custom Biologics Development |
| Allermed Laboratories | , | Greer now responsible for all their products |
| Aduro Biotech | , | Acquiring Chinook Therapeutics, Jun 2020, taking name |
| Elevation Oncology | , | Acquired by Concentra Biosciences, Jul 2025; Strategic Alternatives, Apr 2025 |
| Lumos Pharma | Austin, TX | Rare disease treatment |
| Cyted Health | Cambridge, UK | Non-endoscopic diagnostic platform using minimally invasive cell collection |
| DecImmune Therapeutics | , | Gone 2017 |
| Cullinan Oncology | , | Renamed Cullinan Therapeutics, Apr 2024 |
| Therapeutic Proteins Intl (TPI) | , | Changed name to Adello Biologics, Sep 2016 |
| , | Website down Oct 2025 - Feb 2026 | |
| Adello Biologics | , | Acquired by Kashiv Pharma, Jan 2019 |
| Genetworx | Glen Allen, VA | Molecular diagnostic testing, pharmacogenomics, and pathogen identification |
| , | Pivoted to cybersecurity, Mar 2026 | |
| Beryllium | , | Acquired by UCB Pharma, Jun 2017 |
| Spriaso | , | No news 2019 - May 2025 |
| Arrien Pharmaceuticals | , | Dissolved Sep 2024 |
| CoAxia | , | Closed down Spring 2013 |
| PCI Pharma Services | Rockford, IL | Contract Manufacturing, Services |
| Formedix | , | Acquired by Certara, Oct 2023 |
| Center for Breakthrough Medicines | , | Acquired by SK Pharmteco, Sep 2023 |
| Spectrum Regulatory Solutions | , | Website Gone, Nov 2016 |
| Action Pharma | , | Abbott acquired product, 2012 |
| Oak BioSciences | , | Shut down Nov 2024 |
| JADBio | Vasilika, Greece | Machine Learning Data Analysis |
| Bausch Health | Bridgewater, NJ | Small Molecules |
| Mederi Therapeutics | , | Now Mederi-RF |
| Aquavit Pharmaceuticals | New York, NY | Bioinformatic-driven Drug Delivery Technology |
| Cytogenesis | , | Acquired by BresaGen, Nov 2000 |
| Advanced Clinical | Madrid, Spain | Clinical Research Organization |
| Nexgen Pharma | , | Acquired by LGM Pharma, Jul 2020 |
| Cerevast Medical | , | Renamed Longevity Bioedical, 2022 |
| Bicolor | Belfast, UK | Lab Assays |
| ADAXION Therapeutics | San Diego, CA | Deimmunized Biologics |
| EganLee - Trial Focus | , | Acquired by Precision for Medicine |
| Extract Technology | Huddersfield, UK | Containment Equipment |
| Merus Labs | , | Bought by Norgine, Jul 2017, $342M |
| Quantics Biostatistics | Edinburgh, UK | Biostatistics |
| BioLamina | Sundbyberg, Sweden | Cell Culture Technologies |
| Allied Medical (1) | , | Renamed Admedus, Nov 2013 |
| Sanofi | Midrand, South Africa | Biologics |
| Lumanity | London, UK | Consulting |
| Pyxant Labs | , | Merged with ImaBiotech, 2021 |
| , | Acquired by Waters, 2023 | |
| Cell Microsystems | Durham, NC | Cell Selection Technology |
| Medable | Palo Alto, CA | Clinical Trial Management Software |
| Alaxia | , | Website down Feb 2023 - Jul 2023 |
| Econic Biosciences | London, UK | Extrachromosomal DNA Targeting |
| Avidia | , | Bought by Amgen 2006, Sep 2006, $380M |
| , | Shut down Sep 2025 | |
| Biom'up | , | Assets possibly acquired by Dilon Technologies; Website not fully active Feb 2023, google says closed |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Teleflex Medical | Wurmlingen, Germany | Surgical and Medical Devices |
| CytoRecovery | Blacksburg, VA | Cell Separation & Recovery |
| Astraveus | Paris, France | Manufacturing Technology for cell and gene therapies |
| VitaCyte | Indianapolis, IN | Collagenase |
| Biome Diagnostics | Vienna, Austria | Response Prediction Test for Immunotherapy |
| , | Part of Evogene | |
| ViThera Pharmaceuticals | , | Gone 2017 |
| Epoch Pharmaceuticals | , | Changed name to Epoch Biosciences, 2000 |
| Entasis Therapeutics | , | Acquired by InnoViva, Jul 2022, $113M; AstraZeneca spinout |
| NoyMed | Yerevan, Armenia | Biostatistics, Data management, SAS programming, Medical Writing, Pharmacovigilance and Safety Monitoring |
| Metrion Biosciences | Cambridge, UK | Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays |
| Kronus | , | Website down Apr 2021 - Jun 2021 |
| Geistlich Pharma | Root, Switzerland | Dental/orthopedic bone substitute/tissue regeneration, medical device |
| Mentrik Biotech | , | Gone |
| C2N Diagnostics | St. Louis, MO | Diagnostics & Therapeutics for Alzheimer's |
| Grand Pacific CRO | , | Website down Jan 2024 - Aug 2024 |
| Avivo BioOptics | , | Website down Dec 2022 |
| Thermo Fisher | Frederick, MD | Molecular Biology & Biotech Lab Products |
| Edelweiss Immune | , | Website down Jul 2025; No Info Aug 2022 - Dec 2024 |
| Inmedix | Normandy Park, WA | Neural Immune Diagnostic Technology |
| Gliknik | Baltimore, MD | Cancer and immune disorders therapies |
| SurgiQuest | , | Acquired by ConMed, Jan 2016, $265M |
| Vascular Genesis | , | Website gone Aug 2022 |
| TISSUE SOLUTIONS | , | Acquired by BioIVT, Jul 2021 |
| Key Therapeutics | Flowood, MS | Specialty Pharma |
| AniLocus | Germantown, MD | Preclinical CRO |
| , | Renamed NovaBridge Biosciences, Nov 2025 | |
| Fortress Biotech | Waltham, MA | Small Molecules, Helminth worm eggs as a drug |
| Integer | Penang, Malaysia | Medical & Surgical Devices |
| Commence Bio | , | Gone 2018 |
| Signum Surgical | Galway, Ireland | Bioabsorbable Implant for Anal Fistula |
| Sirna Therapeutics | , | Bought by Merck 2006, Sold to Alnylam Jan 2012 |
| Invenio | Flowery Branch, GA | Wide Array of Devices |
| ReNAgade Therapeutics | , | Acquired by Orna Therapeutics, May 2024 |
| Sirana Pharma | , | Merged with Apexis Bio |
| ViewPoint Therapeutics | , | Assets acquired by Visus Therapeutics, Sep 2022 |
| Pluristyx | Seattle, WA | Research & clinical grade iPSCs products & services, with unique & effective gene editing technologies. |
| Cardiovate | , | Website gone Oct 2019 - Dec 2019 |
| Acelyrin | , | Merged into Alumis, May 2025 |
| TVAX Biomedical | Lenexa, KS | Targeted Cell-Based Immunotherapy |
| Jeta Molecular | Utrecht, Netherlands | qPCR and digital PCR-based molecular diagnostic assays |
| Nanosens | , | Merged into Cardea Oct 2019 |
| EKF Diagnostics | Magdeburg, Germany | Diagnostics |
| Sienna Cancer Diagnostics | , | Merged with Bard1 Life Sciences, Jul 2020 |
| Retroscreen Virology | , | Renamed hVIVO, Apr 2015 |
| Anemocyte | Varese, Italy | Plasmid, mRNA Development & Manufacturing |
| Greenstone | , | Part of Pfizer that became part of Viatris |
| CalAsia Pharmaceuticals | , | Renamed PlexPharma 2016 |
| ChemRegen | , | Seems gone Jan 2022 |
| Alnylam Pharmaceuticals | Maidenhead, UK | RNAi |
| BASF Bioservices | , | Exited business, Sep 2025? |
| Synlab | Munich, Germany | Clinical Lab Services |
| Veridex | , | Bought by J&J, now Part of Janssen Diagnostics |
| Driver BioEngineering | , | believe dba Chimera Bioengineering |
| Valerio Therapeutics | Paris, France | Orphan Diseases, Decoy Oligonucleotides |
| ViroPharma | , | Bought by Shire Jan 2014 |
| Propeller Health | , | Acquired by ResMed, Dec 2018, $225M |
| GSK | Philadelphia, PA | Small Molecules, Vaccines, Biologics |
| Research Diagnostic, Inc. | , | Acquired by Fitzgerald Industries, 2005 |
| Alcami | Charleston, SC | Small Molecule & Biologics Analytical & Formulation Development |
| Formation Bio | New York, NY | AI Drug Discovery |
| Claritas Pharmaceuticals | , | Website down Jul 2022 - Mar 2023; fka Kalytera; Acquiring Salzman Group Feb 2021 |
| Novum Pharma | , | Bankrupt, Feb 2019 |
| AtomVie Global Radiopharma | Hamilton, ON | Radiopharmaceuticals |
| Saneron CCEL Therapeutics | , | No info from 2013 until Feb 2021 |
| , | Website down Sep 2025 - Feb 2026; No news Jan 2021 - Dec 2024 | |
| NeoImmuneTech | Rockville, MD | Immunotherapy |
| Tioma Therapeutics | , | Renamed Arch Oncology |
| Orthocon | , | Assets Acquired by Abryx, Apr 2013 |
| Exodon | , | Website taken over, Jul 2014 |
| |
Stirling, UK | Symbiosis is an FDA-inspected and MHRA-licensed specialist sterile GMP manufacturer of biopharmaceuticals for clinical trials and commercial sales globally. |
| Kegelbell | , | Shut down, Dec 2024 |
| OrphAI Therapeutics | New Haven, CT | AI for cancer |
| Ability Pharma | Cerdanyola , Spain | First-in-class causing autophagy molecules |
| Inceptor Bio | Morrisville, NC | Cell & Gene Therapy Manufacturing Platform |
| Aldatu Biosciences | Watertown, MA | HIV drug resistance phenotyping |
| DDL | Eden Prairie, MN | Device Testing |
| Able Labs | , | big FDA trouble, gone |
| Nitrase Therapeutics | Brisbane, CA | Nitration enzyme |
| CGT Global | Folsom, CA | Tissue Sourcing |
| Premier Research Group | Berkshire, UK | Clinical research & consulting |
| BioFluentLabs | , | Shut down July 2012 |
| HI-Bio | , | Acquired by Biogen, Jul 2024, $1.15B + $650 Milestones; aka Human Immunology Biosciences |
| Bioapp Solutions | Leeds, UK | Contract Research Services |
| Purespring Therapeutics | London, UK | Gene Therapy for Kidney Disease |
| Shore Therapeutics | , | Believe they sold their drug, then cashed out |
| Shattuck Labs | Durham, NC | Immunotherapy platform |
| Meribel Pharma Group | ZZ, UK | Contract Manufacturing |
| , | Website down Jan 2026 - Mar 2026 | |
| ClearView Diagnostics | , | Renamed Koios Medical, May 2017 |
| Abbott | Singapore, Singapore | Diagnostics |
| Ocera Therapeutics | , | Acquired by Mallinckrodt, Dec 2017, $42M |
| InnoRa | Berlin, Germany | Image-guided Therapy |
| Eluminex Biosciences | Suzhou, China | Ophthalmology |
| , | Website down Jul 2025 - Dec 2025 | |
| Bio-ops | , | Now SVA |
| Bikam | , | Acquired by Shire, Aug 2015, $92M |
| Nura Bio | South SF, CA | Small Molecule |
| , | Shut down Jan 2025 | |
| Pfizer | Mumbai, India | Small Molecules, Biologics, Vaccines |
| UCB Pharma | London, UK | Small Molecules, Biologics |
| Alderon Biosciences | , | Presumed gone |
| Protox Therapeutics | , | Now Sophiris Bio |
| Analog Pharma | Princeton, NJ | Generics |
| KritiKal Solutions | Bengaluru, India | Manufacturing advanced medical devices and software |
| SenzaGen | Lund, Sweden | Genomic Assays |
| Penumbra | Berlin, Germany | Vascular / Surgical Devices |
| GTx | , | Acquired by Oncternal via reverse merger ticker, Jun 2019 |
| Artisan Pharma | , | Acquired by Asahi Kasei Pharma, Nov 2011 |
| SmartNuclide Biopharma | Suzhou, China | Radiopharmaceuticals |
| Cardiorentis | , | Website password protected May 2020 - Oct 2020 |
| StemCells Inc | , | Liquidating, May 2016, following trial failure. Being bought by Microbot Medical Aug 2016 for ticker |
| Bryan Corporation | Cincinnati, OH | Airway Dilation System |
| Sea Medical Systems | , | Gone |
| Zeto | Santa Clara , CA | Dry Electrode EEG System |
| Meitheal Pharmaceuticals | Chicago, IL | Generics |
| Novome Biotechnologies | , | Website down Apr 2024 - Aug 2024 |
| Biothera Pharmaceuticals | , | Acquired by Hibercell, Jul 2020 |
| Otsuka | Tokushima, Japan | Small Molecules |
| Crux Biomedical | , | Acquired by Volcano, Dec 2012, $36M |
| Acrux | West Melbourne, Australia | Drug Delivery |
| First Light Biosciences | , | Renamed First Light Diagnostics, Dec 2018 |
| Oxford BioTherapeutics | San Jose, CA | Antibody Therapies |
| Sudo Biosciences | Carmel, IN | Best-in-class precision TYK2 (tyrosine kinase 2) inhibitors |
| Axcella Therapeutics | , | Shut down Dec 2023; fka Axcella Health; fka Pronutria Biosciences, also Pronutria |
| Famar | Thiva, Greece | Contract Manufacturing - Small Molecules |
| Semba Biosciences | , | Acquired by Tosoh Biosciences, Oct 2021 |
| Bioinova | Prague, Czech Republic | Autologous Cell Therapy |
| Avantec Vascular | Sunnyvale, CA | Medical devices and peripheral vascular devices |
| Agilis Biotherapeutics | , | Bought by PTC Therapeutics, Aug 2018, $50M cash + $150M stock |
| |
San Diego, CA | Abzena is the leading end-to-end bioconjugate & complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. |
 |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| Progenra | Malvern, PA | Therapies derived from ubiquitin proteasome pathway |
| Clinicai | , | Website down Mar 2024 - Jul 2024 |
| TeneoTwo | , | Acquired by AstraZeneca, Aug 2022 |
| Aperture Bio | , | Website down Oct 2020 - Jan 2021 |
| Avellino Laboratories | Menlo Park, CA | Gene Therapy, Molecular Diagnostics |
| SironRx | , | Website gone Jul 2015 |
| Apogepha | Dresden, Germany | Urological Treatments & Diagnostics |
| DiaGenic | , | Switched to energy sector |
| Esoterix | , | Bought by LabCorp, May 2005 |
| , | Acquired by Day One Therapeutics, Jan 2026, $285M | |
| Horizon Pharmaceuticals | , | Renamed Horizon Therapeutics |
| enobia pharma | , | Acquired by Alexion Feb 2012 |
| Japan Biomedical | , | Website down Feb 2025 - Jul 2025 |
| Immorna Biotherapeutics | Shanghai, China | Self-Replicating RNA |
| Nektar Therapeutics | San Francisco, CA | Small Molecules, Biologics |
| Blue Turtle Bio | , | Not a registered business in CA, website not working Dec 2020 |
| TriRx Pharmaceutical Services | Huntsville, AL | R&D, manufacturing, packaging and warehousing of non-sterile liquids and semi-solids |
| BioCentriq | , | Renamed Made Scientific, Mar 2025 |
| Redx Pharma | Macclesfield, UK | Small Molecules |
| Triphase Accelerator | , | Website down Oct 2022 - Apr 2023 |
| Dynacure | , | Merged with Flamingo Theraputics, Mar 2023 |
| KCRN Research | Germantown, MD | Clinical & Regulatory Services |
| Respira Labs | , | Renamed Samay Health, Oct 2022 |
| TherapyX | Buffalo, NY | Nanoparticulate immune therapeutics |
| Kate Therapeutics | , | |
| Ectycell | , | Part of Cellectis |
| NitroMed | , | Bought by private equity company, Jan 2009, effectively dissolved; Sole drug sold on to Arbor Pharmaceuticals, 2012 |
| EXO Biologics | Liège, Belgium | Exosomes |
| Eden Biodesign | , | Bought by Watson |
| Swiss American CDMO | Carrollton , TX | Topicals CDMO |
| Jiuzhou Pharma | Changshu, China | Fully integrated solutions in small molecule and peptide API drug development & production from clinical stage to commercialization |
| Micell Technologies | , | Seems shut down 2019 |
| , | Assets Acquired by Biomemory, Mar 2026 | |
| Eli Lilly | Alcobendas, Spain | Small Molecules, Biologics |
| Repros Therapeutics | , | Acquired by Allergan, Dec 2017 |
| Funxional Therapeutics | , | Bought by Boehringer Ingelheim, Jul 2012 |
| RJS Biologics | , | Shut down Feb 2019 |
| Neurobiological Technologies | , | Voluntarily Liquidated, Sep 2009 |
| Solidus Biosciences | , | Website gone, Sep-Oct 2017 |
| Abmaxis | , | Acquired by Merck, May 2006, $80M |
| ASTrego Diagnostics | , | Acquired by Sysmex, May 2022 |
| Fortuna Fix | , | Website down Aug 2020 - Oct 2020 |
| Bradmer Pharmaceuticals | , | Shell pivoted to blockchain |
| , | Website down Dec 2025 - Apr 2026 | |
| Immunome | Bothell, WA | Cancer Immunotherapy |
| Bion Enterprises | , | Acquired by MBL International, 2008 |
| , | Acquired by Xoma, Feb 2026; fka Torus Therapeutics | |
| Genia Technologies | , | Acquired by Roche, Jun 2014 |
| ImmuneSensor Therapeutics | Dallas, TX | Novel medicines that target the cGAS-STING pathway |
| Jaden BioScience | , | Website down, Sep 2016-Mar 2017 |
| Viral Genetics | , | Now VG Life Sciences |
| Immunomedics | , | Acquired by Gilead, Oct 2020 |
| Envigo | , | Acquired by Inotiv, Nov 2021; Swapped assets with Covance to exit preclinical CRO business |
| JOINN Biologics | Richmond, CA | Biologics CDMO |
| Spirit Pharmaceuticals | , | Website down, Nov 2024 - Mar 2025 |
| MSN Labs | Hyderabad, India | Generics |
| Novus Therapeutics | , | Renamed Eledon Pharmaceuticals, Jan 2021 |
| Sierra Surgical | , | Shut down Feb 2019 |
| Immunai | Ramat Gan, Israel | Immunes system mapping with AI |
| Rio Grande Neurosciences | , | Assets sold to Endonovo Therapeutics, Dec 2017, $4.5M |
| Conatus Pharmaceuticals | , | Acquired by Histogen via Reverse Merger, Jun 2020 |
| Open Biosystems | , | Acquired by Thermo-Fisher 2008 |
| NJ Biopharmaceuticals | Princeton, NJ | Contract Research |
| , | Website down Oct 2025 - Jan 2026 | |
| InnoSkel | , | Website down Sep 2024 - Mar 2025 |
| Ablation Frontiers | , | Acquired by Medtronic, Jan 2009, $225M |
| Opsonix | , | Shut down May 2018 |
| Villaris Therapeutics | , | Acquired by Incyte, Nov 2022, $70M + $1.36B milestones |
| Astellas | Dublin, Ireland | Small Molecules, ADC, Cell Therapy, Gene Therapy, Viral, Antibodies |
| Vidara Therapeutics | , | Acquired by Horizon Pharma, Sep 2014 |
| StemGenex | , | Filed Chapter 7 Bankrupt, Sep 2019 |
| Paragon 28 | Englewood, CO | Foot & Ankle Implants |
| Infectex | , | Website taken over May 2020 |
| Abzyme Therapeutics | Royersford, PA | Modular single domain VHH antibody fragments for immunotherapy |
| Novex Innovations | Winston-Salem, NC | Contract Research, Clinical Manufacturing |
| C3 Jian | , | Now C3J Therapeutics |
| Tesis Labs | , | Renamed Tesis Biosciences, Nov 2021 |
| Uptake Medical | s-Hertogenbosch, Netherlands | Non-surgical, non-implant therapy to improve breathing |
| Pinteon Therapeutics | , | Website down Dec 2024 - May 2025 |
| Curamir Therapeutics | , | Shut down 2020 |
| GalChimia | Touro. A Coruña, Spain | Chemistry CRO |
| Iogyn | , | Acquired by Boston Scientific, May 2014 |
| Rib-X | , | Changed to Melinta Therapeutics, Oct 2013 |
| CordenPharma | Caponago, Italy | Contract Small Molecules |
| Cellular Intelligence | Boston, MA | AI-Driven Cell Therapy |
| Viant Medical | Laconia, NH | Contract Medical Devices |
| BioAge Labs | Richmond, CA | Computational platform that explores a universe of proprietary and public data to identify and target the molecular factors that influence longevity |
| Salignostics | Jerusalem, Israel | Saliva-based Diagnostics |
| Asana Medical | , | Renamed Regentys, Nov 2017 |
| Antex Biologics | , | Bought by BioPort, Jun 2003 |
| NervGen Pharma | Vancouver, BC | Peptide inhibitor of protein tyrosine phosphatase sigma |
| Intent Biologics | Rochester, MN | Regenerative Exosome Biologics |
| Caris Life Sciences | Phoenix, AZ | Diagnostics |
| Integrated Bioanalysis | , | Website down Jul 2022 - Nov 2022; aka Friley Consulting |
| Carefusion | , | Bought by BD, Mar 2015, $12.2B; Spun out of Cardinal Health Sep 2009 |
| BetaLogics | , | Absorbed by ViaCyte, Feb 2016 |
| , | Shut down Jan 2024 | |
| Misonix | , | Acquired by Bioventus, Oct 2021, $518M |
| , | Website down May 2025 - Dec 2025 | |
| ResVerlogiX | Calgary, AB | Small Molecules |
| Bioquark | , | Website down May 2022 - Oct 2022 |
| eNeura | , | Chapter 7 bankruptcy, Aug 2020 |
| Blacktrace | , | Acquired by Unchained Labs, Jul 2023 |
| DirectSens | Klosterneuburg, Austria | Enzyme-based biosensors for healthcare diagnostics |
| Apolife | , | Renamed Biosavita |
| , | Acquired by Shionogi, Jun 2023, $140M | |
| GLyPharma Therapeutic | , | Acquired by Theracon, Oct 2018 |
| Bioxalis | , | Bought by Procyon Biopharma, Jun 2005, $3.5M |
| ADViSYS | , | Acquired by VGX Pharmaceuticals, 2007 |
| Tissue Regeneration Systems | , | Website dated, emails not working, no pictures on LI Sep 2020 |
| Jupiter Bioscience | , | Not active business according to MD DOS, website gone |
| Heart Tronics | , | Effectively defunct after scandal |
| Ogenx Therapeutics | , | Closed Aug 2016 |
| Exquiron | , | Acquired by Aptuit, Apr 2016 |
| Fosun Pharma | Hong Kong, China | Small molecules, diagnostics, traditional |
| Alrise Biosystems | , | Part of Medical Center, Jun 2023 |
| sRNA Dx | , | aka sRNAlytics |
| PNP Therapeutics | Birmingham, AL | Outlicensed sole product Sep 2021 |
| Syros Pharmaceuticals | , | Website down Apr 2025 - Sep 2025; Merged with Tyme Technologies, Sep 2022 |
| , | Employees gone, Mar 2026; Website down Feb 2026 - Mar 2026 | |
| Micelle BioPharma | , | Website down Oct 2021 - Mar 2022; fka Sancilio & Company |
| GenapSys | , | Sale to Sequencing Health approved Sep 2022; Chapter 11 bankruptcy, Jul 2022 |
| Cairn Research | Kent, UK | Scientific Instruments |
| Kasocio | , | Liquidated, Dec 2019 |
| Certara | Sheffield, UK | Biosimulation software, technology and services to transform traditional drug discovery and development. |
| Bach Pharma | , | Shut down late 2023 |
| MSM Protein Technologies | , | Gone Jun 2019 |
| Abacus Diagnostica | , | Now part of Uniogen, Jan 2022 |
| Best-Link Bioscience | Shanghai, China | Precision cancer treatment and tumor immunotherapy |
| PharmaLex | Berlin, Germany | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Bay Bioanalytical | , | Acquired by Pacific BioLabs |
| Mattson Jack | , | Now Kantar Health 2009 |
| G2B Pharma | , | Seems abandoned, Apr 2018, Site gone |
| Silence Therapeutics | Hoboken, NJ | RNAi |
| Craif | Tokyo, Japan | Urine-based microRNA liquid biopsy tests |
| Pharma Tech Industries | Union, MO | Contract Manufacturing |
| PainReform | , | Website copyright 2008 as of Mar 2019 |
| Praxis Precision Medicines | Boston, MA | Genetic Neuroscience Treatments |
| Bioneer A/S | Hørsholm, Denmark | CRO/CDMO for early drug development with protein and in vitro expertise |
| Predictive Biotech | , | Website gone Dec 2023 - Jul 2024 |
| Melanovus Oncology | , | Assets acquired by Cipher Pharmaceuticals, Jan 2015 |
| NextGen Sciences | , | Defaulted, sued by employees |
| ProTgen | Virtual, | Targeted Notch activators to reconstitute the adaptive immune system |
| MMI Genomics | , | Assets bought by Neogen |
| Seracare Life Sciences | Gaithersburg, MD | Biologic Diagnostic Products |
| Viz.ai | San Francisco, CA | Healthcare Image Analysis |
| Ganymed Robotics | Paris, France | Surgical Robotics for Orthopedics |
| Athos Therapeutics | Torrance, CA | AI-Based Precision Therapeutics |
| Amplyx Pharmaceuticals | , | Acquired by Pfizer Apr 2021 |
| AOP Orphan Diseases | Dubai, UAE | Orphan disease treatments |
| Kailo Pharma | , | |
| Hovione | Macau, China | Contract Manufacturing |
| ADS BIOTEC | Omaha, NE | Lab Instruments, Consumables |
| |
Beijing, China | BioDuro | fully integrated CRDMO | 28 years. We can take our clients from target identification through to commercial drug product manufacturing. |
| JenaValve | Munich, Germany | Transcatheter aortic valve replacement system |
| , | Part of Greenpharma | |
| Duet BioTherapeutics | , | Parent company is worthless public company, Jan 2025 |
| BioPact | Austin, TX | Carbon-nanotube based rebar |
| Lxbio Pharmaceuticals | Lisbon, Portugal | Bacteriophages, Antibody Fragment, Topical |
| |
Long Island City, NY | Mispro is a contract vivarium organization (CVO) offering a network of full-service vivarium rental facilities for preclinical rodent studies. |
| Cytovale | South SF, CA | Sepsis Detection |
| Clariance Spinevision | Dallas, TX | Spinal Surgery Devices |
| Adhera Therapeutics | , | Website down May 2023 - Dec 2023 |
| In Cell Art | , | Website taken over Feb 2025 |
| CrossFire Medical | , | Inactive as of Mar 2018 |
| VirionHealth | , | Renamed Virion Biotherapeutics, Sep 2018 |
| Novapeutics | , | Website down Oct 2022 - Mar 2023 |
| Minakem | Dunkerque , France | API Manufacturing |
| , | Seems to have shut down mid 2025 | |
| Rarebase | , | Renamed Transcripta Bio, Apr 2024 |
| Abeille Pharmaceuticals | , | Closed 2017 |
| Curacyte Discovery | , | Acquired by The Medicines Company, Aug 2008 |
| NeuroKaire | Kearny, NJ | CNS Drug Development Data |
| BIONIK Laboratories | , | Website down Apr 2025 - Sep 2025 |
| Icosavax | , | Acquired by AstraZeneca, Feb 2024, $800M |
| CF PharmTech | Suzhou, China | Specialty Respiratory Pharmaceuticals |
| SynteractHCR | , | Created when Synteract merged with Harrison Clinical Research, reverted to Synteract |
| Bellwether Bio | , | Acquired by Guardant Health, Apr 2019, $10M + $20M milestones |
| Akamara Therapeutics | , | No info or website, May 2021 - Aug 2021 |
| Charles River Laboratories | Barcelona, Spain | Research Animal Models and Preclinical Research |
| Orchestra Therapeutics | , | Shut Down 2009 |
| Delta4 AI | Wollerau, Switzerland | AI Drug Discovery |
| CelerisTx | , | Renamed Adhesion Therapeutics, May 2024 |
| Formula Pharmaceuticals | , | Merged into CoImmune, Apr 2020 |
| Lanthio Pharma | , | Website down Jul 2022 - Nov 2022 |
| Viventia | , | Acquired by Eleven Bio, Sep 2016, $30M in stock |
| N-Side | Louvain-La-Neuve, Belgium | Clinical Trial Supply Chain Software |
| , | Renamed ElisiGen, Dec 2025 | |
| , | No news 2015 - Jan 2026 | |
| Corindus Vascular Robotics | , | Acquired by Siemens Healthineers, Oct 2019 |
| TenNor Therapeutics | Suzhou, China | Digestive therapies |
| ReCyte Therapeutics | , | Website down Sep 2020 - Aug 2021; BioTime transferred ownership to spinout AgeX Therapeutics |
| Xtuit | , | Gone Jul 2018 |
| Harbour BioMed | Shanghai, China | Antibodies and fragments |
| RaySearch Laboratories | Seoul, Korea | Cancer Research Software |
| AMSBIO | Cambridge, MA | Numerous assays, reagents and lab tools of all types |
| Century Pharmaceuticals Ltd | Gujarat, India | Generics |
| Recipharm | Stockholm, Sweden | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Alize Pharma II | , | Acquired by Jazz Pharmaceuticals, Jun 2016, €8M + €10M milestones |
| Saluda Medical | Bloomington, MN | Spinal Cord Stimulation Device |
| Wavelength Pharmaceuticals | , | Website down Nov 2024 - Jun 2025; business acquired from Perrigo and rebranded, 2017 |
| Novum Medical | , | Website down Jul 2022 - Nov 2022 |
| Avenu Medical | , | Acquired by Medtronic, Oct 2020 |
| Ausio Pharmaceuticals | , | No website activity 2014 - Dec 2020 |
| Vivalis | , | Merged with Intercell to become Valneva, May 2013 |
| Accuray | Morges, Switzerland | Directed Radiation Therapy |
| Gator Bio | Palo Alto, CA | Next-gen BLI technology for higher signal strength, wider detection range, greater regeneration capabilities. |
| , | Bought by Fujifilm, Mar 2015, $307M | |
| Suntra MedTech | Bedford, NH | Various Drug Delivery Devices |
| Eleusis | , | Acquired by Beckley PsyTech, Oct 2022 |
| Epic Bio | , | Rebranded as epicrispr, Aug 2024 |
| Aligos Therapeutics | South SF, CA | Therapies for hepatologic diseases and viral infections |
| Nagi Bioscience | Saint-Sulpice, Switzerland | Organism-on-a-chip Testing |
| GenoTwin | , | Website down Feb 2025 - Jul 2025 |
| Oncorx Pharmaceuticals | , | Not registered in GA, no news 2015-2024 |
| Accell Clinical Research | Kiev, Ukraine | Clinical Research |
| Oxford BioDynamics | Oxford, UK | Diagnostics |
| Augusta Pharmaceuticals | , | Shut down July 2009 |
| NemaPharm | , | Defunct? |
| CryoXtract | , | Funding cut off, Apr 2017, shut down Aug 2017 |
| , | Acquired by Versiti, Jul 2023 | |
| Glycotechnica | , | Website down Nov 2022 - Mar 2023 |
| Antigen Express | , | Renamed NuGenerex Immuno-Oncology, Mar 2020 |
| Rapport Therapeutics | Boston, MA | Precision medicines for neurological disorders |
| Itero Biopharmaceuticals | , | Website Gone |
| OMass Therapeutics | Oxford, UK | Drug Discovery by high-res Mass Spec of intact protein assemblies |
| RNAGene | Seoul, Korea | Immunotherapy, Vaccines, Drug Delivery System |
| Aspen Pharmacare | Oss, Netherlands | Small Molecules |
| Gen Plus | Munich, Germany | Formulation |
| Roslin Cells | , | Renamed RoslinCT |
| Clear Scientific | Cambridge, MA | Small-molecule sequestrants |
| MGC Pharmaceuticals | , | Renamed Argent BioPharma, Feb 2024 |
| Actinium Pharmaceuticals | New York, NY | Targeted Radiotherapy |
| Alltracel Pharmaceuticals | , | Bought by HemCon, 2008 |
| Glyconics | Basingstoke, UK | IR Spectroscopy for POC Diagnostics |
| Lumenis | Tokyo, Japan | Energy-based medical treatments |
| Alcami | Durham, NC | Small Molecule & Biologics Analytical & Formulation Development |
| Axela Biosciences | Whippany, NJ | Cell Assays, Immunoassays, Flow Cytometry, Spatial Biology |
| Harlan Laboratories | , | Merged into Huntingdon Life Sciences, Nov 2015, renamed Envigo |
| X-Chem Pharmaceuticals | Waltham, MA | Small molecule drug discovery |
| Cognate Bioservices | , | Acquired by Charles River, Mar 2021; $875M |
| Modular Medical | San Diego, CA | Insulin Pump |
| Ipsen | Wrexham, UK | Biologics |
| Personal Genome Diagnostics | Baltimore, MD | Tumor Genome Analysis |
| Novartis Animal Health | , | Acquired by Lilly |
| OphthaliX | , | Renamed Wize Pharma, Nov 2017 |
| Plumeria Therapeutics | , | Website password protected, Nov 2018 - May 2020, gone Dec 2020 |
| SARcode | , | Bought by Shire Mar 2013 |
| Apogenix | Heidelberg, Germany | Protein therapeutics |
| PureIMS | Roden, Netherlands | Disposable Dry powder Inhaler |
| Lyvgen Pharma | Shanghai, China | Immuno-oncology Antibody |
| Mirvie | South SF, CA | RNA Platform for Pregnancy Issues |
| Envue | Nesher, Israel | Therapeutic Ultrasound Devices |
| Banner Life Sciences | , | Acquired by Cycle Pharma, Jan 2025 |
| Daiichi Sankyo | Fukushima, Japan | Small Molecules |
| Thermo Fisher | Middletown, VA | Lab Supplies and Equipment |
| Galt Pharmaceuticals | Atlanta, GA | Diagnostics for Osteoarthritis, Small Molecules |
| Ebewe Pharma | , | Now Sandoz |
| Apredica | , | Rebranded as Cyprotex Jan 2014. Aug 2010 acquisition of Cyprotex |
| Immunicum | , | Renamed Mendus, Jun 2022 |
| Biosynexus | , | Sold to PE 2005, unsure of fate |
| AmKor Pharma | , | Founded 2004, GNT Pharma subsidiary |
| NeuroPhage Pharmaceuticals | , | Renamed Proclara Biosciences, Sep 2016 |
| Tasso | Seattle, WA | Blood-collection products |
| Fractyl Health | Burlington, MA | Thermal ablation therapy, Gene Therapy |
| Thermo Fisher | Shanghai, China | Molecular Biology & Biotech Lab Products |
| Assurance Scientific Laboratories | Austin, TX | Molecular Technologies |
| EndoClot Plus | , | Website down Feb 2024, no updates 2011-2024, no Linkedin Feb 2024 |
| NeoCura | Guangzhou, China | Personalized Vaccines |
| OncoTartis | , | Website down Jun 2024 - Nov 2024 |
| VectorBuilder | Chicago, IL | Recombinant Vectors & Viruses |
| CARGO Therapeutics | , | Acquired by Concentra Biosciences, Aug 2025 |
| Raytest | Angleur, Belgium | Software for Radiopharmacy |
| Kindeva Drug Delivery | Woodbury, MN | Drug Delivery CDMO |
| Jazz Pharmaceuticals | Palo Alto, CA | Small Molecules |
| OncoStatyx | , | No website Aug 2020 - Jul 2024 |
| Adare Pharma Solutions | Pessano con Bornago, Italy | CDMO providing end-to-end integrated services, from product development through commercial manufacturing and packaging. |
| Alume Biosciences | San Diego, CA | Nerve Illumination Technology |
| InnoPharma | , | Acquired by Pfizer, Sep 2014, $225M + $135M milestones |
| Morphochem | , | Acquired by Deinove, May 2018 |
| Getinge | Gothenburg, Sweden | Medical Technology |
| Avid Radiopharmaceuticals | , | Bought by Lilly, Nov 2010, $800M |
| Modulate Therapeutics | , | Website gone Feb 2021; Yale affiliated |
| Cerus Endovascular | , | Acquired by Stryker, May 2023 |
| Millipore | Jaffrey, NH | Purification, Analytic Biologics, Discovery |
| BEAT BioTherapeutics | , | Closed 2017 |
| PaxVax | , | Acquired by Emergent Biosolutions, Oct 2018, $270M |
| , | Website down Nov 2025 - Apr 2026 | |
| 76Bio | , | Shut down Jan 2025 |
| Laxxon Medical | New York, NY | 3D-printed oral dosage forms |
| LIFNano Therapeutics | , | Website hijacked May 2023 - Aug 2023 |
| Axial3D | Belfast , UK | 3D printing for medical use |
| GenePeeks | , | Website gone Nov 2018, Everyone left company |
| Ipsen | Boulogne-Billancourt, France | Small Molecules, Biologics |
| Fosun Pharma | Moscow, Russia | Small molecules, diagnostics, traditional |
| Design Therapeutics | Carlsbad, CA | Drugs targeting disorders caused by nucleotide-repeat expansions |
| iOrganBio | Chapel Hill, NC | Human Cell Production Platform |
| GT Apeiron | Burlingame, CA | AI Drug Development |
| Charles River Laboratories | Raleigh, NC | Research Animal Models and Preclinical Research |
| SimplicityBio | , | Acquired by Precision for Medicine, Mar 2019 |
| Illimis Therapeutics | Seoul, Korea | Biologics based on a chimeric fusion protein platform |
| Illumaxbio Technology | Chengdu, China | Diagnostic Machine |
| MultiGEN Diagnostics | , | Bought by PCLS Apr 2014 |
| Aztech Sciences | , | Website gone Jun 2021 |
| Avexegen Therapeutics | , | Website taken over Dec 2024; No business filings Dec 2022 - Jan 2025 |
| Endovasc | , | Bankrupt 2008 |
| Viant Medical | Aura, Germany | Contract Medical Devices |
| Casana | Rochester, NY | Toilet Seat to Analyze Heart |
| InnoUp | Noáin, Spain | Oral Drug Delivery Solutions |
| Kriya Therapeutics | Morrisville, NC | Gene Therapy |
| Parvus Therapeutics | South SF, CA | Peptide-MHC-coated nanoparticles |
| Touchlight | Hampton, UK | Rapid, enzymatic GMP DNA manufacturing for advanced therapeutics |
| Avobis Bio | Newark, DE | Stem Cell Therapy Plug |
| nference | Cambridge, MA | Clinical AI |
| SCA Pharma | Little Rock, AR | 503(b) outsourced compounding |
| Singleron Biotechnologies | Cologne, Germany | Single-Cell Sequencing, Service Lab |
| Peapod Bio | Chicago, IL | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Aspen Pharmacare | Durban, South Africa | Small Molecules |
| Circle Biologics | , | Website redirects to Celling Biosciences, Jan 2016 |
| Oxford Cancer Analytics | Oxford, UK | Liquid Biopsy |
| Vasopharm | , | Renamed Verinos Pharma, Jan 2023 |
| Famar | Baranzate, Italy | Contract Manufacturing - Small Molecules |
| Clearbridge Biomedics | , | Renamed Biolidics |
| Avero Diagnostics | Irving, TX | Diagnostic Lab |
| Menarini | Dresden, Germany | Small Molecules |
| Anapharm Bioanalytics | Barcelona, Spain | Bioanalytical Services |
| Newormics | , | Renamed vivoVerse, late 2022 |
| DKP Genomics | , | Dissolved Jul 2025 |
| MonomerChem Inc | , | Ancient website, no employees on LI |
| Chengdu Kanghong Pharmaceutical Group | Chengdu, China | Therapeutics & Medical Devices |
| Amoytop Biotech | Xiamen, China | Biologics |
| BioVision | , | Acquired by Abcam, Oct 2021, $340M |
| Alinea Pharmaceuticals | , | Seem to be subsidiary of NKT Therapeutics |
| TransPharma Medical | , | Assets acquired by Syneron, Mar 2012 |
| US WorldMeds | Louisville, KY | Specialty Pharmaceuticals |
| Ergomed | Moscow, Russia | Clinical Research |
| Covenant Therapeutics | , | Gone |
| EAG Laboratories | Tempe, AZ | Analytical & Synthesis Services |
| neoSurgical | , | Shut down 2017 |
| Biotest Pharmaceuticals | Dreieich, Germany | Biologics |
| BISC Global | , | Acquired by Excelra, Apr 2023 |
| ALS Biopharma | , | Website down Aug 2023 - Dec 2023, LI page gone Nov 2023 |
| Arcion Therapeutics | , | Merged into Anesiva, Aug 2009 |
| InnoSer | Diepenbeek, Belgium | Preclinical CRO |
| Tessel Biosciences | Cambridge, MA | Virtual tissues for Drug Simulations |
| SiteOne Therapeutics | , | Acquired by Lilly, Aug 2025, $1B |
| Recida Therapeutics | , | |
| Fluigent | Le Kremlin-Bicetre, France | Microfluidics |
| Creganna Medical | , | Acquired by TE Connectivity, Apr 2016, $895M |
| Qlarity Imaging | , | Website down Jan 2024 - Sep 2024 |
| Anavex Life Sciences | New York, NY | Small Molecules |
| AMF Medical | , | Acquired by Tandem Diabetes, Jan 2023 |
| Cernitin | , | Merged with Bioferment & Sapec in 1994 to become Cerbios-Pharma |
| CytoImmune Therapeutics | Toa Baja, PR | Cancer Immunotherapy |
| SciNeuro Pharmaceuticals | Shanghai, China | Neuro Treatments |
| Numab Therapeutics | Horgen, Switzerland | Antibody Therapies |
| VALIS Genomics | , | Website down Feb 2021 - Jun 2021 |
| Lavipharm | Peania Attica, Greece | Small molecules |
| Omthera Pharmaceuticals | , | Bought by AstraZeneca, May 2013, $323M |
| Xention | , | All programs halted or disposed of by 2016 |
| NeuroDiscovery | , | Company renamed Oncosil Medical |
| NovaRock Biotherapeutics | Ewing, NJ | Antibody Therapeutics |
| , | Website down Dec 2025 - Apr 2026 | |
| Kedrion Biopharma | Fort Lee, NJ | Human Plasma-Derived Therapies |
| Barr Pharmaceuticals | , | Acquired by Teva, Jul 2008, $7.46B |
| DiagnosTechs | Federal Way, WA | Non-Invasive Saliva, Stool and Urine Diagnostics |
| CTIBIOTECH | Philadelphia, PA | Tissue Sample |
| Navitor Pharmaceuticals | , | Shut down Dec 2023 |
| Karius | Redwood City, CA | Diagnostics |
| NuAire | Plymouth, MN | Lab Equipment |
| Allele Diagnostics | Spokane, WA | Microarray and cytogenetic testing services |
| LipoSeuticals | Monmouth Junction, NJ | Sterile Injectables |
| Crosstrees Medical | , | Website gone Dec 2017; Habitually late filing business docs |
| DARA Biosciences | , | Merged with Midatech Pharma, Jun 2015 |
| Ascle Therapeutics | , | No website Nov 2023 - Jul 2025 |
| 3-Dimensional Pharmaceuticals | , | Acquired by J&J, Jan 2003, $88M |
| Chroma Medicine | , | |
| Quality CDMO | Fort Worth, TX | Liquid, OTC, Suppository CMO |
| InfaCare | , | Acquired by Mallinckrodt, Sep 2017, $80M + $345M milestones |
| ProPharma Group | Fort Washington, PA | Consulting |
| NurExone Biologic | Haifa, Israel | Proprietary platform for producing and loading exosomes with pharmaceutical cargo targeting spinal cord injuries intranasally |
| Enovalife | Lyon, France | Biometrics and medical writing services |
| Genestack | Cambridge, UK | Genomics operating system |
| Cardero Therapeutics | , | Renamed Epirium, Dec 2019 |
| CORPAK MedSystems | , | Acquired by Avanos Medical, Apr 2016, $174M |
| Fitzgerald Industries International | , | Acquired by Biosynth, Aug 2023, $30M; Acquired by Trinity Biotech, 2004 |
| LG Chem Life Sciences | Seoul, Korea | Small Molecules, Vaccines, Biologics, Aesthetic Medicine |
| Puzzle Medical Devices | Montréal, QC | Transcatheter heart pump |
| MEI Pharma | , | Pivoted to Crypto, Sep 2025; Strategic alts, Jul 2024; fka Marshall Edwards, moved from Australia 2010 |
| Cipher Surgical | Coventry, UK | Surgical Vision Platform |
| Fosun Pharma | London, UK | Small molecules, diagnostics, traditional |
| Beyond Drug Development | Brisbane, Australia | Early Stage BioPharma Services |
| Bioelectron | , | Assets bought by PTC Therapeutics; fka Edison Pharmaceuticals |
| Sequiserve | , | Website down Jan 2024 - Jul 2024 |
| |
Ravensburg, Germany | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| HeartVista | , | Renamed Vista.ai |
| Mimetogen Pharmaceuticals | , | No news 2021 - May 2025 |
| Curiosity Diagnostics | , | Acquired by Bio-Rad, Aug 2022, $100M + $70M Milestones |
| Biologics Resources | , | Website not working Sep 2023 - Aug 2024 |
| Infinity Pharmaceuticals | , | Chapter 11 Bankruptcy, Sep 2023 |
| Avecia | , | Bought by Nitto Denko |
| Deargen | Daejeon, Korea | AI-Drug Discovery Services |
| Oncoceutics | , | Acquired by Chimerix, Jan 2021, $78M |
| Mercy BioAnalytics | Waltham, MA | Early cancer detection based on analysis of single extracellular vesicles |
| Beckman Coulter Genomics | , | Bought by Genewiz, Dec 2015 |
| Cambridge Isotope Laboratories | Tewksbury, MA | Stable Isotopes |
| Altergen Laboratory | , | Website down Mar 2024 - Jul 2024 |
| Smithers Avanza | , | Renamed Smithers, Sep 2019 |
| Ray Therapeutics | Berkeley, CA | Optogenetic Gene Therapy |
| Bicoll | Planegg, Germany | Plant-Based Drug Discovery, Synthesis |
| ClinArt | , | Now ClinArt MENA |
| , | Renamed AtaiBeckley | |
| Corza Medical | Pößneck, Germany | Surgical Devices |
| CytoGenix | , | Gone, CEO charged by SEC with being con artist |
| Novostia | Lausanne, Switzerland | Artificial Heart Valves |
| Cyclana Bio | Cambridge, UK | Endometriosis Treatment |
| Polymer Therapeutics | , | Website down Mar 2020 - Dec 2020, listed on BioNJ |
| Pyramid Pharma Services | Costa Mesa, CA | Contract Filling, Lyophilization, Manufacturing, Analytical Services |
| Girihlet | Oakland, CA | Diagnostic Technology using TCR Sequencing |
| UDL Laboratories | , | Acquired by Mylan 1996 |
| INOVIQ | Notting Hill, Australia | Cancer Diagnostics |
| preCARDIA | , | Acquired by Abiomed, Jun 2021 |
| |
Tustin, CA | Avid Bioservices offers commercial biologics development & manufacturing services |
| AFYX Therapeutics | Hørsholm, Denmark | Topical Drug Delivery for Mucosal Diseases |
| Prothena | Dublin, Ireland | Antibodies for neuro / immune targets |
| UNEEG Medical | Allerod, Denmark | Ultra long-term, subcutaneous EEG monitoring systems |
| Olainfarm | , | Renamed Olpha, Jun 2024 |
| Benvenue Medical | , | Assets acquired by Spinal Elements, Dec 2020 |
| Amabiotics | , | Renamed Stellate Therapeutics, Jun 2020 |
| SR Pharma | , | Now Silence Therapeutics |
| MicroProbe | , | Changed name to Epoch Pharmaceuticals, 1995 |
| Clinlogix | , | Bought by NAMSA, Aug 2021 |
| Haemonetics | Boston, MA | Blood Management Solutions |
| Sequenta | , | Acquired by Adaptive Biotechnologies, Jan 2015 |
| BioDot | Irvine, CA | Equipment |
| Satellite Bio | Newton, MA | Hepatocyte Grafts |
| Qing Bile Therapeutics | , | Website down Mar 2023 - Dec 2023 |
| Qorvo Biotechnologies | , | Acquired by Zomedica, Oct 2023 |
| Precision Spine | Parsippany, NJ | Spinal Devices |
| Padlock Therapeutics | , | Acquired by BMS, Mar 2016, $225 + $375 milestone |
| Nittobo America | Murrieta, CA | Bulk antisera manufacturing |
| Applied BioMath | , | Acquired by Certara, Dec 2023 |
| Angios Biotech | Innsbruck, Austria | Treatments for Vascular Diseases |
| SciCann Therapeutics | , | Website down Dec 2021 - Apr 2022 |
| |
Kitchener, ON | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| West Pharma | Cayey, PR | Pharmaceutical Supplier |
| Trilogy Pharmaceuticals | , | Became Rx3 Pharmaceuticals |
| Sun Pharmaceuticals | Ahmednagar, India | Generic Small Molecules, APIs |
| Retromer Therapeutics | , | Website down Mar 2025 - Aug 2025 |
| MSN Laboratories | Hyderabad, India | APIs, Generics |
| 3T Biosciences | South SF, CA | TCR Therapies |
| Caldera Medical | Westlake Village, CA | Surgical Implants for Women |
| C3J Therapeutics | , | Merged with AmpliPhi Biosciences, May 2019; fka C3 Jian |
| Aesku Diagnostics | Wendelsheim, Germany | Research Diagnostics |
| Aspira Labs | , | Renamed Aspira Women's Health |
| Phlow | Richmond, VA | Small Molecule CDMO |
| Lumenis | Gurgaon, India | Energy-based medical treatments |
| AVITA Medical | Valencia, CA | Autologous Skin Cell Harvesting & Treatments Device |
| HelixBind | Boxborough, MA | Blood infection Diagnostics |
| SereDigm | , | Gone Nov 2009 |
| Noveome Biotherapeutics | Pittsburgh, PA | Biologics |
| Hutman Diagnostics | , | Website down May 2020 - Oct 2020 |
| Evonik Industries | Essen, Germany | API Manufacturing |
| Neuro Kinetics | , | Acquired by Neurolign, Oct 2019 |
| 4s3 Bioscience | , | Changed named to Valerion Therapeutics 2012 |
| Cole-Parmer | Quebec, QC | Lab equipment, consumables, support to accelerate discovery, ensure compliance, and enhance productivity. |
| GSL Biotech | , | Acquired by Dotmatics |
| , | Renamed Benthic Genomics, Sep 2025 | |
| Abnovo | , | Gone |
| Laborie | Portsmouth, NH | Medical Devices |
| MOBILion Systems | Chadds Ford, PA | Analytical Diagnostic Technology |
| Theramex | London, UK | Women's Health |
| Diagast | Loos, France | Transfusion Reagents |
| Inflammatory Response Research | , | Website gone Jul 2021 |
| Koligo Therapeutics | , | Acquired by Orgenesis, Oct 2020 |
| Odyssey Therapeutics (2) | Ann Arbor, MI | Small Molecules, Biologics |
| Flux Biosciences | , | Shut down, ~2022 |
| Synergetics USA | , | Acquired by Valeant, Sep 2015, $190M; Neurosurgical portfolio sold to Stryker, Feb 2016 |
| SMSbiotech | San Marcos, CA | Stem Cell Therapy |
| CNA Diagnostics | , | Website down Oct 2021 - Feb 2022 |
| Amendia | , | Acquired Spinal Elements, Apr 2017, took their name |
| Eurogentec | Seraing, Belgium | Biologics |
| Sylentis | Madrid, Spain | RNAi Treatments |
| Journey Medical | Scottsdale , AZ | Skin Treatments |
| IDT Biologika | Dessau-Rosslau, Germany | Contract Research, Development & Manufacturing (Biologics, Liquid Small Molecules) |
| Infinity Bio | Baltimore, MD | Reactome Services |
| Scribe Biosciences | , | Website down Jul 2024 - Dec 2024 |
| Pharmacyclics | , | Bought by AbbVie, $21B May 2015 |
| 3Scan | , | Merged with Transcriptic, to become Strateos, Jun 2019 |
| Brillian Pharma | Beijing, China | Innovative Pediatric Dosage Forms |
| Intrexon | , | Renamed Precigen |
| Staidson Biopharma | , | Website down Jan 2025 - Jul 2025 |
| Advantar Laboratories | , | Acquired by Eurofins, Mar 2016 |
| CALiMMUNE | , | Acquired by CSL Behring, Aug 2017 |
| Global Genomics Group | , | Renamed G3 Therapeutics |
| Allylix | , | Acquired by Evolva, Nov 2014, $59M stock |
| Duality Biologics | Shanghai, China | ADCs |
| WideCELLS | , | Shut down Nov 2019 |
| Alfa Scientific Designs | Poway, CA | Rapid POC Diagnostics |
| Voxtur Clinical Research | Chennai, India | Clinical Research Services |
| Novarad | Provo, UT | Imaging Software and Technology |
| ChoiceSpine | Knoxville, TN | Spinal Implants |
| Immunetrics | , | Acquired by Simulations Plus, Jun 2023 |
| Biotrial | Rennes, France | Clinical Trials & Scientific Services |
| Amylgen | , | Website down Sep 2022 - Feb 2023 |
| GlycoEra | Boston, MA | Custom Glycan Platform |
| SanBio BV | Uden, Netherlands | Antibodies |
| Semafore Pharmaceuticals | , | Gone? |
| NextRNA Therapeutics | , | Winding down Aug 2025 |
| Rejuvenon | , | Changed name to Sapphire Therapeutics 2005 |
| Makefield Therapeutics | , | Website Gone |
| Fosun Pharma | Frankfurt, Germany | Small molecules, diagnostics, traditional |
| Taron Solutions | Hong Kong, China | CDMO for biologics |
| Enterome | Evry, France | Microbiome-related diseases, diagnostics |
| ApexQubit | , | Website down Apr 2022 - Aug 2022 |
| Albumedix | , | Acquired by Sartorius, Sep 2022, £415M |
| |
Garnet Valley, PA | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| EQRx | , | Acquired by Revolution Medicines, Nov 2023 for slightly over EQRx cash on hand |
| Zai Lab | Beijing, China | Small Molecules |
| Ajuta Therapeutics | , | Founders gone as of May 2021 |
| , | Website down Nov 2025 - Apr 2026 | |
| GemPharmatech | Nanjing, China | Genetically Engineered Mouse Models |
| ROTOP Pharmaka | Dresden, Germany | Pharma CDMO |
| Pace | Greensburg, PA | Analytical Testing, CDMO |
| Biogen | Durham, NC | Small Molecules, Biologics, Biosimilars, ASO |
| Vaxxilon | , | Merged into Idorsia, Jun 2020 |
| PrimeraDx | , | Bought by Qiagen, Jun 2014 |
| Apthera | , | Merged with Rxi Pharmaceuticals |
| Sionna Therapeutics | Waltham, MA | Small Molecule Targeting CF |
| , | Renamed ExGen Dx, Jul 2025 | |
| NanoTag Biotechnologies | Göttingen, Germany | Single-domain antibody solutions |
| Baylor Genetics | Houston, TX | Genetic Testing |
| Katalyst Healthcares and Life Sciences | South Plainfield, NJ | Clinical Research, Consulting & staffing |
| , | Website under construction Feb 2025 - Jan 2026 | |
| Bacchus Vascular | , | Bought by Covidien, Jun 2009, undisclosed terms |
| iRhythm Technologies | Cypress, CA | Remote heart analysis |
| Solid Form Solutions | , | Acquired by Avista Pharma, Jan 2018 |
| Jonakayem Pharma - Formulation | , | Website down Jun 2024; fka Kayem Pharmaceutical |
| Procella Therapeutics | , | Subsumed into SmartCella, Jun 2025 |
| Alfa Chemistry | Holbrook, NY | Building blocks, reagents, catalysts, reference materials, and research chemicals |
| ImCheck Therapeutics | Marseille, France | Immuno-modulatory antibodies |
| Paradromics | Austin, TX | Brain Computer Interfaces |
| Oxford Endovascular | Oxford, UK | Neurovascular Devices |
| Actera Pharmaceuticals | , | Closed |
| Mepha | Basel, Switzerland | Generics |
| Phenoquest | , | Website gone, Oct 2015 |
| Tetris Pharma | , | Acquired by Arecor Therapeutics, Aug 2022 |
| Ranok Therapeutics | Waltham, MA | Innovative targeted protein degradation technology for the discovery and development of novel therapeutics |
| HemoShear Therapeutics | , | Website down Jul 2024 - Dec 2024 |
| RevoluGen | Berkshire, UK | DNA Extraction Kits |
| Sight Sciences | Menlo Park, CA | Ophthalmology surgical devices |
| Envetar Therapeutics | , | Renamed MOTE Therapeutics, Sep 2023 |
| GemoPharm | , | No news 2017-2022 |
| Radiomics | Liège, Belgium | AI Image Analysis & Diagnosis |
| Merck KGaA | Darmstadt, Germany | Small Molecules, Purification Equipment, etc. |
| BioDelivery Sciences International | , | Acquired by Collegium Pharmaceuticals, Mar 2022, $604M |
| Thermo Fisher | Whitby, ON | Molecular Biology Supplies |
| Antipodean Pharmaceuticals | , | Switched to beauty products |
| Quantum SI | Guilford, CT | Single-molecule NGS |
| Starkey | Eden Prairie, MN | Hearing Aids |
| , | Seems to be News website, Jan 2026 | |
| Genoa Pharmaceuticals | , | Changed name to Avalyn Pharmaceuticals, Jul 2017 |
| Pareto Biotechnologies | , | Shut down, Jul 2015 |
| Rempex Pharmaceuticals | , | Acquired by The Medicines Company Dec 2013, $140M |
| BioRelix | , | Acquired by Pfizer, Sep 2005 |
| IntegraGen | Evry, France | Biomarker identification, diagnostics |
| MedOne Surgical | Sarasota, FL | Cannulae for Retina Surgery |
| Charles River Laboratories | Harlow, UK | Research Animal Models and Preclinical Research |
| Broadwing Bio | South SF, CA | Antibody based drugs for blindness |
| Abbott | Abbott Park, IL | Nutrition, Diagnostics, Devices, Animal Health |
| CanCure | , | No news 2017 - 2024 |
| Ionetix | Lansing, MI | Radiopharmaceutical |
| Talaria Therapeutics | , | Acquired by Esperion Therapeutics, Oct 2000, $7.3M shares |
| Sekisui Diagnostics | Charlottetown, PE | Diagnostics |
| Biomissile | Suzhou, China | Fully Human Antibody Therapies |
| Galera Therapeutics | , | Liquidated Aug 2024 |
| Atara Biotherapeutics | Aurora, CO | Peptibody, Monoclonal Antibody, Cell Therapy |
| Carewave Medical | , | Renamed Soovu Labs, May 2019 |
| Replace Therapeutics | , | Acquired by Tome Biosciences, Jan 2024, $185M |
| Tabby Therapeutics | , | No info Aug 2024 - Jun 2025; Mentioned in NatBio Jun 2024 |
| Silere Medical Technology | , | Shut down Dec 2013 |
| Roxro Pharma | , | Acquired by Luitpold 2010 |
| Pharmaterials | , | Acquired by Quotient Sciences, Nov 2017 |
| |
, Moldova | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| ALine Biosciences | , | Administratively Dissolved, Jun 2018 |
| PBS Biotech | Camarillo, CA | Single-Use Bioreactors |
| Actagene Oncology | , | Acquired by Ignyta May 2013 |
| Transend Therapeutics | , | Renamed Aera Therapeutics, Jul 2022 |
| Qkine | Cambridge, UK | Stem Cell Growth Factors |
| Aspreva | , | Acquired by Vifor Pharma |
| Envision Genomics | , | Website gone Nov 2019 |
| Persion Pharmaceuticals | , | Seems to have been a shell to transfer pain asset |
| Numira Biosciences | , | Employees gone, no info, presumed defunct |
| BrainScope | Bethesda, MD | EEG characterization |
| PredxBio | Pittsburgh, PA | Image Analysis |
| Regen Biologics | , | Bankrupt, product sold to Stryker |
| Medefil | Glendale Heights, IL | Specialty Pharmaceuticals |
| OncoOne | Vienna, Austria | Cancer Drug Discovery |
| Novalex Therapeutics | , | Website Gone, Oct 2018 |
| Tricida | , | Liquidating May 2023; Chapter 11 bankruptcy, Jan 2023 |
| ISD Immunotech | , | Website down Mar 2023 - Dec 2023 |
| HBI Amerilab Technologies | Plymouth, MN | Effervescent tablets, powders, chewables |
| Aelin Therapeutics | , | Website down Dec 2023 - Apr 2024 |
| Lonza | Bend, OR | Contract Manufacturing, Development; Lab Systems, Research Products |
| Calibrant | , | Closed |
| Polaris Pharma | San Diego, CA | Biologics for Cancer, CDMO |
| Kaléo | Glen Allen, VA | Drug Delivery Technology |
| Wisdom Pharmaceutical | Haimen, China | Contract Manufacturing |
| C-Ray Therapeutics | Shanghai, China | Radiopharmaceuticals |
| Adcendo | Frederiksberg, Denmark | Developing antibody-drug conjugates for cancer |
| Closed Loop Medicine | Cambridge, UK | Digital, Device combinations |
| MOLCURE | Kanagawa, Japan | AI-Driven Drug Discovery |
| Cygnus Technologies | Leland, NC | ELISA kits, Antibodies, Services |
| , | Acquired by PE, assets repackaged into AMR Bio, Feb 2026 | |
| SGX Pharma | , | Acquired by Eli Lilly Jul 2008 |
| STRM.BIO | Cambridge, MA | Extracellular vesicles (EVs) to deliver gene therapies |
| Ultragenyx Pharmaceutical | Somerville, MA | Small Molecules, Biologics |
| Eyenuk | Woodland Hills, CA | AI Eye Screening |
| AC Diagnostics | , | Website from 2004 |
| I Peace | Palo Alto, CA | iPSC Cell Banking, Research Products, Cell Manufacturing |
| eXegenics | , | Merged with Froptix and Acuity Pharmaceuticals to become Opko Health Mar 2007 |
| Samyang Biopharmaceuticals | , | Website down Feb 2023 - Jul 2023 |
| Alvarado Therapeutics | , | Renamed MapLight Therapeutics, Sep 2019 |
| Bioo Scientific | , | Acquired by Perkin Elmer, Aug 2016 |
| Eliksa Therapeutics | Doylestown, PA | Regenerative Medicine |
| Biorchestra | Cambridge, MA | Novel RNA-based Therapeutics |
| Ciba Vision | , | Bought by Alcon, bought by Novartis |
| Signalife | , | Renamed Heart Tronics |
| Comac Medical | Sofia, Bulgaria | European CRO |
| Flightpath Biosciences | Detroit, MI | Reformulations for Tick-borne Diseases |
| SkinVent Pharmaceuticals | , | Doesn't seem serious; Single-person company?, Dec 2019 |
| PhenomeX | , | Acquired by Bruker, Oct 2023, $108M; fka Berkeley Lights |
| Agilent | Lexington, MA | High-Throughput Screening Equipment, Imaging instruments |
| Elpiscience | Shanghai, China | Cancer Immunotherapies |
| AnchorDx | Fremont, CA | High-throughput sequencing platform |
| BioLaurus | , | Business filings late Mar 2022; Website down Dec 2024 - Feb 2025 |
| InnovHeart | Milan, Italy | Atrioventricular valve replacement |
| Samumed | , | Renamed Biosplice Therapeutics, Apr 2021 |
| Oncoinvent | Oslo, Norway | Radiopharmaceuticals |
| Until Labs | San Francisco, CA | Reversible Cryopreservation for Organ Procurement |
| New Drug Associates | , | Renamed Phaedrus Pharmaceuticals, Sep 2002 |
| MRM Health | Ghent, Belgium | Microbiotic Therapies |
| Universal Sequencing Technology | Carlsbad, CA | Single Cell Sequencing |
| Delpharm | Boucherville , QC | Contract Manufacturing |
| Zentriforce Pharma | Heidelberg, Germany | Analytical Services |
| BioMarin Pharmaceutical | Bogotá, Colombia | Biologics |
| Allux Medical | , | Shut down, Feb 2009 |
| Inno Biologics | , | Website gone Jun 2020 |
| Immune Regulation | , | Renamed Revolo Biotherapeutics |
| mdgroup | Berkshire, UK | Clinical Trial Solutions |
| GeneTether Therapeutics | , | Renamed Rize Oncology, Jan 2025 |
| Thermo Fisher | Bend, OR | CDMO |
| TheraLogics | , | Been around since 2008, but no site or current info |
| Merck | Rahway, NJ | Small Molecules, Biologics |
| Visus Therapeutics | , | Merged with Tenpoint Therapeutics, Dec 2024 |
| Panacea Pharmaceuticals | , | Renamed Sensei Biotherapeutics, May 2018 |
| Azad Pharma | Hangzhou, China | APIs, generics |
| AcerMed | , | Bankrupt, 2007, bought by Ophthalmic Imaging Systems Jan 2008 |
| CarrierGene Biotech | , | Merged with NuProbe, Jan 2020 |
| , | Website down Sep 2025 - Dec 2025 | |
| AdvancedCath | , | Acquired by TE Connectivity, Feb 2015, $190M |
| Auxeris Therapeutics | , | Gone 2006-2007 |
| Orphion Therapeutics | , | Website down Nov 2024 - Apr 2025 |
| Lengo Therapeutics | , | Acquired by Blueprint Medicines, Dec 2021, $250M + $215 Milestones |
| BravoVax | Wuhan, China | Vaccines: Viral Vector, Recombinant Protein, Conjugate, VLP |
| Iovance Biotherapeutics | San Carlos, CA | Adoptive Cell Therapy |
| TRIGR Therapeutics | , | Acquired by Compass Therapeutics, Jun 2021, $50M |
| Trial Runners | Dickinson, ND | Ophthalmology Clinical Research |
| Javelin Pharmaceuticals | , | Merged with Hospira 2010 |
| Predix Pharmaceuticals | , | Renamed Epix Pharma |
| Genspeed Biotech | Rainbach, Austria | Infectious Disease Diagnostics |
| Pharmaron | Northamptonshire, UK | R&D Services |
| Cellec Biotek | Basel, Switzerland | System for 3D Cell & Tissue Culture |
| Synthego | Redwood City, CA | Synthetic RNA for CRISPR use |
| CytoTherapeutics | , | Acquired and took on StemCells Inc name |
| NanoBio Systems | , | Shut Down Jun 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Integra LifeSciences | Rietheim-Weilheim, Germany | Medical Devices |
| Acetylon Pharmaceuticals | , | Acquired by Celgene, Dec 2016 |
| 10X Genomics | Pleasanton, CA | Genomics Platform |
| BioSyntech | , | Bought by Piramal |
| Anumana | Cambridge, MA | AI ECG reading |
| Abviva | , | Gone, 2008 |
| Zymeron | Durham, NC | Solution to prevent myelosuppression |
| Byonyks Medical Devices | Bangalore, India | Home-based, bloodless peritoneal dialysis machines |
| Canbex Therapeutics | , | Website down May 2019 - Nov 2019 |
| AxioMx | , | Acquired by Abcam, Nov 2015, $20M + $25 milestones |
| PhoreMost | Cambridge, UK | Biologics |
| Haplomics | , | Website down Jan 2019 - Mar 2019 |
| , | Shut down Jan 2025 | |
| Midland Certified Reagent Company | , | Website down Apr 2022 - Aug 2022 |
| Cytognos | Santa Marta de Tormes, Spain | Flow Cytometry Solutions |
| Litos | , | Marked as closed on Google, Apr 2022; Website down Oct 2021 - Apr 2022 |
| NightHawk Biosciences | , | Renamed Scorpius Holdings, Jan 2024 |
| Akarna Therapeutics | , | Acquired by Allergan, Sep 2016, $50M + milestones |
| HistoIndex | Hangzhou, China | Digital Pathology |
| VaxCyte | San Carlos, CA | Conjugate vaccines and protein-based vaccines |
| Akatalyst Technologies | Chennai, India | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Click Therapeutics | New York, NY | Digital Therapeutics |
| Proteovant Therapeutics | , | Acquired by SK Biopharmaceuticals, Aug 2023 |
| AltPep | Seattle, WA | Alternating Peptides for Neurological Diseases |
| Inflammatix | Sunnyvale, CA | Sepsis Diagnostics |
| Curative Therapeutics | , | Website down Jan 2020 - Dec 2020 |
| Cardiospire | , | Not registered in CA Feb 2025; Website down Sep 2024 - Jan 2025; fka Respirix |
| Hologic | Mississauga, ON | Diagnostic, Imaging |
| GT Apeiron | Shanghai, China | AI Drug Development |
| Brazos Bridge Pharmaceuticals | , | Renamed Verndari, Apr 2016 |
| Eli Lilly | Mayaguez, PR | Small Molecules, Biologics |
| Envigen Pharmaceuticals | , | Website gone May 2018 |
| Axio Research | , | Acquired by Cytel, Jun 2019 |
| Curadev | Noida, India | Immuno-oncology |
| Curovir | Stockholm, Sweden | Broad-spectrum antiviral treatments for enterovirus infections |
| Triangle Pharmaceuticals | , | Acquired by Gilead, 2003, $464M |
| Topica Pharmaceuticals | , | Website Gone, Dec 2016 |
| AdoRx Therapeutics | , | No news 2018-2023, employees don't list job, CEO is an investor |
| Microbix Biosystems | Mississauga, ON | Antigen production, molecular diagnostics, viral vectors |
| GeNO | , | Renamed Vero Biotech, 2018 |
| Igenomix | Paterna, Spain | Contract genetic testing for reproductive health; covid-19 pcr |
| ClearSight | , | Website down Apr 2025 - Sep 2025 |
| Diagenode | Denville, NJ | Lab Assays & Reagents |
| Erba Diagnostics | , | Website down Dec 2021 - Jul 2022 |
| Vivocore | , | Never registered as business in UK; No website Feb 2022 - Dec 2022; fka InterVivo/Transpharmation |
| Trion Pharma | , | Insolvent, technology acquired by Lindis Biotech |
| Italchimici | , | Acquired by Recordati, May 2016 |
| Cody Laboratories | , | Bought by Lannett, 2007 |
| WallabyPhenox | Laguna Hills, CA | Cranial navigation, catheter |
| Lynk Pharmaceuticals | Hangzhou, China | Kinase Inhibitor |
| Dilon Technologies | Newport News, VA | Probes, Imaging Devices |
| STIMIT | , | Website gone May 2022; under construction Nov 2021 - Apr 2022 |
| Gen-probe | , | Acquired by Hologic 2012 |
| Mountain View Clinical Research | , | Rebranded as Tribe Clinical |
| MURO PHARM | , | Dissolved, May 2007 |
| Reproductive Health Science | , | Acquired by Perkin-Elmer, Jul 2018 |
| Calyptus Pharmaceuticals | , | Website down May 2023 - Dec 2023 |
| NuVo Pharmaceuticals | , | Renamed Miravo Healthcare, Dec 2020 |
| Marsala Biotech | , | No news since 2016 as of Oct 2022; Strategic Alternatives, Oct 2016 |
| NEOsphere Biotechnologies | Planegg, Germany | Small molecule degraders as therapeutic agents |
| Uquifa | Barcelona, Spain | APIs, Contract Manufacturing |
| Senores Pharmaceuticals | Hoschton, GA | Complex Generics |
| Revogenex | , | Basically everyone is gone. Email asking about company bounced |
| FLUIDDA | New York, NY | Functional Respiratory Imaging |
| DNAMx | , | Renamed Adela |
| WILEX | , | Renamed Heidelberg Pharma Oct 2017 after acquiring them |
| Immune-Onc Therapeutics | Palo Alto, CA | Immuno-Oncology |
| Intact Vascular | , | Acquired by Philips, Aug 2020, $275M |
| A/C Diagnostics | , | Active as of 2017, Severely dated website, Jan 2019 |
| Correvio (1) | , | Acquired by Cardiome, Nov 2013, name resurrected and taken by Cardiome, May 2018 |
| Smith and Nephew | Memphis, TN | Sports Medicine, Trauma, Wound Care, etc. |
| Chemgenics Pharmaceuticals | , | Acquired by Millennium Pharmaceuticals, Feb 1997, $89M |
| Nocimed | , | Renamed Aclarion |
| CavoGene LifeSciences | , | Website down Feb 2021 - Sep 2021 |
| Vitrobio Pharma | , | Website down Apr 2024 - Aug 2024 |
| Terapio | , | Website Gone, Sep 2020 |
| Blockade Medical | , | Acquired by BALT, Sep 2016 |
| Frontier Bio | Hayward, CA | Engineered Tissues for Medical Testing |
| Flamel | , | Rebranded Avadel Pharmaceuticals Jan 2017 |
| Jaguar Gene Therapy | Lake Forest, IL | AAV-Based Gene Therapies |
| Renasant Bio | Berkeley, CA | Small molecules treating autosomal dominant polycystic kidney disease |
| Ducentis BioTherapeutics | , | Acquired by Arcutis Biotherapeutics, Sep 2022, $30M + $370M milestones |
| Biotecnol | , | Website down Dec 2024 - May 2025 |
| COR Clinical Research | , | Shut down after owner passed |
| iSTAR Medical | Wavre, Belgium | Minimally-invasive glaucoma surgery |
| Cellerix | , | Acquired by TiGenix Mar 2011 |
| Mandala Biosciences | , | Dissolved, Jun 2019 |
| Trigenesis Therapeutics | , | Acquired by Dr. Reddy's Laboratories |
| Freyr Solutions | Reading, UK | Regulatory Consulting |
| Pneumolabs | , | Dissolved Sep 2018 |
| Axium Pharmaceuticals | , | Dissolved |
| Alteon | , | Renamed Synvista Therapeutics, Jan 2009 |
| Summit Therapeutics | Oxford , UK | Utrophin modulation technology |
| PolyMedics Innovation | Kirchheim unter Teck, Germany | Synthetic Skin Technology |
| Suneris | , | Renamed Cresilon, Sep 2016 |
| Sanguine Biosciences | Woburn, MA | Clinical Trial Specimen Collection |
| PAIRimmune | , | Acquired by Pacific Biomarkers, Jun 2019 |
| CureTech | , | Website down, Apr 2019 - Aug 2019; Three attempted sales failed |
| Altasciences | Auxvasse, MO | Contract Research |
| Sentrimed | Mullica Hill, NJ | Oral Therapies Targeting Podoplanin |
| Regis Technologies | Morton Grove, IL | Synthesis & Separations |
| Ella Therapeutics | , | Website down Aug 2022 - Feb 2023 |
| Randox Laboratories | Crumlin, UK | Clinical Diagnostics |
| Cargene | , | Renamed Lerna Biopharma, Sep 2023 |
| Arevipharma | Radebeul, Germany | APIs, CDMO |
| PromoCell | Heidelberg, Germany | Cellular Products |
| , | Website down Dec 2025 - Apr 2026 | |
| SCARLETRED Holding | Vienna, Austria | Skin Analysis App |
| Pharmaron | Beijing, China | R&D Services |
| AmpTec | , | Acquired by Merck KGaA, Jan 2021 |
| Arranta Bio | , | Acquired by Recipharm, Apr 2022 |
| GLR Laboratories | , | Renamed MDR Laboratories, Jan 2025 |
| BeRNA Therapeutics | , | Company dissolved due to intellectual property issues, 2015 |
| Merck | Elkton, VA | Small Molecules, Vaccines, Biologics |
| Matchpoint Therapeutics | Cambridge, MA | Covalent Medicines |
| Calla Lily Clinical Care | London, UK | Vaginal Drug Delivery |
| Mitologics | Paris, France | CRO mitochondrial effects of chemicals or biology |
| Haystack MRD | Baltimore, MD | Minimal residue disease testing for oncology |
| , | Acquired by Dark Horse Consulting, Oct 2024 | |
| Complexa | , | Website down Jul 2022 - Nov 2022 |
| ViQi | Santa Barbara, CA | AI and Imaging for Drug Discovery |
| Worldwide Clinical Trials | Rome, Italy | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| , | Acquired by Lantheus, Jan 2025 | |
| Axovant Sciences | , | Renamed Sio Gene Therapies, Nov 2020 |
| , | Acquired by Mirum Pharmaceuticals, Jan 2026 | |
| Alacrity Biosciences | , | Gone post-2011 |
| Earthgenes Pharmaceuticals | , | Closed 2014 |
| Stemina Biomarker Discovery | Madison, WI | Drug Screening & Development |
| Corza Medical | Somerset, UK | Surgical Devices |
| |
South SF, CA | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Rontis | Zug, Switzerland | Generics, Contract Manufacturing |
| Peachtree Bioresearch Solutions | Marietta, GA | Clinical Research Services |
| SV ChemBioTech | Edmonton, AB | Novel design and synthesis of organic molecules to support and accelerate the drug discovery research |
| Medicept | Ashland, MA | Medical Device Compliance Consulting |
| Tevard Biosciences | Boston, MA | tRNA-based Gene Therapies |
| Aspen Pharmacare | Mexico City, Mexico | Small Molecules |
| Pharmatech Oncology | , | Renamed Pharmatech |
| Vernay | Griffin, GA | Fluid Control Solutions |
| UniD Manufacturing | Seraing, Belgium | CDMO for Sustained Delivery Solutions |
| JSC Valenta Pharmaceuticals | Moscow, Russia | Small Molecules, OTC |
| Prometheus Labs | San Diego, CA | Diagnostics |
| Khloris Biosciences | San Jose, CA | iPSC Library |
| AbbVie | Maidenhead, UK | Diagnostics, Devices |
| Capsugel | , | Bought by Lonza, Dec 2016, $5.5B |
| Pfizer | St. Louis, MO | Small Molecules, Biologics |
| Glaukos | San Clemente, CA | Glaucoma Devices |
| HemoCue | Ängelholm, Sweden | Diagnostics |
| PharmaLex | Uttar Pradesh, India | Development Consulting, Regulatory Affairs Consulting, Quality Management and Compliance, Pharmacovigilance to the Biopharma, Pharma and Medical Device Industries. |
| Ergomed | London, UK | Clinical Research |
| TRIA Bioscience | , | Shut down Aug 2021 |
| BioDevek | , | Formerly LabCentral, seems gone |
| ExCellThera | Montréal, QC | Growing blood stem cells for therapeutic use |
| Resonetics | Westborough, MA | Contract Medical Device Manufacturing & Development |
| TheraPix Biosciences | , | Renamed SciSparc, Jan 2021 |
| Sift Biosciences | San Carlos, CA | Peptide immunotherapy platform |
| Intronn | , | Acquired by VIRxSYS, Sep 2007 |
| AcuraStem | Pasadena, CA | Patient-based Therapeutics |
| AirLife | Grand Rapids, MI | Respiratory & Anesthesia Devices |
| Ipsen | Les Ulis, France | Small Molecules, Biologics |
| Taconic Biosciences | Germantown, NY | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| Agensys | , | Acquired by Astellas Pharma, Nov 2007, $387M + $150M milestones |
| AcrannoLife Genomics | Chennai, India | Genetic Predisposition Tests |
| Abbexa | Cambridge, UK | Antibodies, Research products |
| POS Bio-Sciences | , | Rebranded as Keylead Feb 2019, switched business model to plant-derived products |
| ExThera Medical | Martinez, CA | Blood filtration |
| |
Islandia, NY | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| Jazz Pharmaceuticals | Philadelphia, PA | Small Molecules |
| 149 Medical | , | Shut down Dec 2022 |
| AryoGen Pharmed | Tehran, Iran | Biosimilar Therapeutic Monoclonal Antibodies |
| Synthon Biopharmaceuticals | , | Renamed Byondis, Apr 2020; Spun out of Synthon 2012 |
| Depomed | , | Changed name to Assertio Therapeutics, Aug 2018 |
| Shamrock Structures | , | Shut Down, Jan 2018 |
| Avance Biosciences | Houston, TX | CRO providing GLP/GMP-compliant assay development, assay validation, and sample testing services |
| Milenia Biotec | Giessen, Germany | Lateral Flow Rapid Tests |
| Cytotech Labs | , | Renamed Berg Pharma 2009 |
| Dispatch Bio | San Francisco, CA | Immuno-oncology |
| Reach Neuro | Bristol, RI | Spinal Cord Stimulation |
| ADC Therapeutics | Epalinges, Switzerland | Antibody-drug conjugates |
| Arxx Therapeutics | , | Merged with Oxitope to become Calluna, Jan 2024 |
| Derma-Cell Research | , | Website gone Nov 2019 |
| Pfizer | Durham, NC | Small Molecules, Vaccines, Biologics |
| , | Website down Aug 2025 - Jan 2026 | |
| NAMSA | Selby, UK | Medical Research Organization - Medical Devices |
| Biodeal Pharmaceuticals | Nalagarh, India | Generics |
| Triad Therapeutics | , | Acquired by Monogram Energy Oct 2009 |
| SensoGenic | , | Shut down; Website, LI page gone Nov 2023 - Dec 2023 |
| Scope International | Mannheim, Germany | Full-Service Contract Clinical Research Organization - Pharma, Biotech & Device |
| iNanoBio | Menlo Park, CA | 3D nanopore – transistor device for sequencing the whole human genome with high accuracy |
| SCA Pharma | Windsor, CT | 503(b) outsourced compounding |
| nanoComposix | San Diego, CA | Nanoparticles, contract work |
| , | Acquired by Generic Specialties, May 2016 | |
| Bioneur | , | Website gone, Dec 2018, Founder is also with a new company |
| Quattro Research | Planegg, Germany | IT Solution Consultants |
| Pendopharm | Montreal, QC | Specialty Pharmaceuticals |
| Thermo Fisher | Raritan, NJ | Lab Supplies and Equipment |
| AxioMed | , | President left in 2018, not registered in MA |
| Bilayer Therapeutics | , | Shut down Aug 2024 |
| Exacis Biotherapeutics | , | Sold platform to Eterna, May 2023 |
| TopoGEN | Buena Vista, CO | Assays, Antibodies, Cell Repair, Services |
| Revance | Nashville, TN | Movement Disorder Treatment |
| Unither Pharmaceuticals | Rochester, NY | CDMO |
| SOTIO Biotech | Boston, MA | Active Cellular Immunotherapy |
| BeOne Medicines | San Carlos, CA | Small Molecules, Monoclonal Antibodies |
| STX-Med | , | Renamed Cefaly |
| Codman Neurosurgery | , | Bought by Integra Life Sciences, Oct 2017, $1.045B |
| Mevion Medical Systems | Surrey, UK | Radiation Therapy |
| Avenzo Therapeutics | San Diego, CA | Oncology Treatments |
| Sokol GxP Services | Skillman, NJ | Equipment Qualification Services |
| LignaMed | , | Seems gone May 2024; No news 2019 - Apr 2025; Closely associated with Polycore Therapeutics |
| Silicon Biosystems | , | Acquired by Menarini, Sep 2013 |
| Stago | Taverny, France | Diagnostics |
| Horizon Therapeutics | , | Acquired by Amgen, Oct 2023; fka Horizon Pharmaceuticals |
| IQVIA | Parsippany, NJ | Clinical Research |
| NeoStem | , | Changed name to Caladrius Biosciences Jun 2015 |
| Neogene Biosciences | , | Amateurish website that is not working Jul 2015 |
| Beckman-Coulter | Loveland, CO | Flow Cytometry |
| CStone Pharmaceuticals | Shanghai, China | Immuno-Oncology |
| Apigenix | Prague, Czech Republic | Chemistry & Pharmacology Services |
| Cambridge Cancer Genomics | , | Acquired by Dante Labs, Oct 2021 |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| Celsis | , | Now AAIPharma |
| Henderson Morley | , | Bankrupt |
| Visgo Therapeutics | , | Gone Jun 2018 |
| OD-OS | Irvine, CA | Retinal Laser |
| Taconic Biosciences | Ejby, Denmark | Genetically engineered rodent models and services. Specialists in Mouse Model Humanization and GEMs Management. |
| EyeCyte | , | Gone 2014 |
| Dac Biotech | Hangzhou, China | Monoclonal Antibody Drug Conjugates |
| Sanyal Biotechnology | , | Merged with MetabAxis |
| Ception | , | Bought by Cephalon, Jan 2009, $250M |
| Valtech Cardio | , | Acquired by Edwards Lifesciences, Jan 2017, $340M |
| ProSci | Poway, CA | Antibodies, etc. |
| , | Renamed Create Medicines, Oct 2025 | |
| Acuity Spatial Genomics | , | Now Bruker Spatial Genomics |
| BBI Solutions | Crumlin, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| EndoGastric Solutions | , | Acquired by Merit Medical, Jul 2024, $105M |
| Octapharma | Vienna, Austria | Plasma Products |
| Bio Genuine Biotech | Shenzhen, China | Small Molecules |
| Avantra Biosciences | , | Changed name to Courtagen, switched to Marijuana Testing |
| OncoMyx Therapeutics | , | No employees on Linkedin Dec 2023; Website redirecting to Linkedin Nov 2022 - Dec 2023 |
| SimBioSys | Chicago, IL | Tumor Analysis Software |
| CERo Therapeutics | South SF, CA | Cellular Immunotherapy |
| PolyMedix | , | Bankrupt Apr 2013 |
| Snorx | , | Renamed Zelegent, May 2015 |
| Triclinic Labs | Lafayette, IN | Contract Small Molecule Development Services |
| CFL Biotech | , | Website gone Jul 2020 |
| Biorchestra | Daejeon, Korea | Novel RNA-based Therapeutics |
| Velocity Clinical Research | Edgewater, FL | Clinical Research |
| Muvon Therapeutics | Zurich, Switzerland | Autologous cell therapy for the regeneration of skeletal muscle tissue |
| xMD Diagnostics | , | No news 2020 - Feb 2025 |
| Revolo Biotherapeutics | Cambridge, UK | Therapies for inflammatory and immunological diseases |
| Dren Bio | San Carlos, CA | Protein Therapeutics |
| Kyalin Biosciences | , | Acquired by Retrophin, Dec 2013 |
| Qiagen | Germantown, MD | Molecular Diagnostics, Assays, Reagents, Antibodies |
| DNTOX | Düsseldorf, Germany | Human Cell Models |
| Serenus Biotherapeutics | , | Closed HQ in CA, no employees on LI, CEO left, no website updates since 2015, not sure they do anything |
| Lumasonix | , | Website down Sep 2024 - Feb 2025 |
| Transcend Medical | , | Acquired by Alcon, Feb 2016, up to $740M |
| Kapadi | Raleigh, NC | Oncology Clinical Trials |
| Starpharma | Abbotsford, Australia | Antibacterial |
| Freudenberg Medical | Carpinteria, CA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| SPRI Clinical Trials | , | Website down Sep 2020 - Mar 2021 |
| Aixial Group | Sevres, France | Full-Service CRO with expertise in Oncology, Radiopharma, Cell & Gene Therapy and Rare Diseases |
| ArriVent Biopharma | Newtown Square, PA | Small Molecule, Antibody-Drug Conjugate |
| Flow Eighteen38 | , | |
| Novoprotein | , | Website down Jun 2021 - Dec 2021 |
| Concinnity Genetics | Glasgow, UK | RNA-control of gene therapies |
| GV20 Therapeutics | Shanghai, China | Antibody Therapeutics |
| HALIX BV | Leiden, Netherlands | Protein Production, Contract packaging |
| AiM Medical Robotics | Fort Lauderdale, FL | MRI-compatible intraoperative robotics |
| Trident BioPharm Solutions | London, UK | Life Science Consulting |
| TNI Biotech | , | Renamed Immune Therapeutics |
| Jaggi Ophthalmic | New Delhi, India | Ophthalmic Equipment |
| , | Acquired by MMS, Feb 2025 | |
| Emerald Bioscience | , | Renamed Skye Bioscience |
| Merrion Pharmaceuticals | , | Sold IP to Novo Nordisk, Nov 2015, €9.4M; liquidating |
| Biotrofix | , | Gone, Dec 2014 |
| Parallax Medical | , | Acquired by ArthroCare, Jan 2004, $35M; Sold to NeuroTherm, Jul 2011 |
| MedSpark | San Luis Obispo, CA | Medical Device Design & Development |
| Compugen | San Francisco, CA | Biologics |
| Viant Medical | Jiangsu, China | Contract Medical Devices |
| Medrobiotics | , | Bankrupt, May 2024 |
| ReviR Therapeutics | Brisbane, CA | Building a Scalable Platform addressing unmet therapeutic needs by Revising RNA with Small Molecules |
| gel-e Life Sciences | , | Renamed Medcura, Dec 2019 |
| Vante | Tucson, AZ | Catheter Tipping Equipment |
| Arecor | Little Chesterford, UK | Formulation Technology |
| Opsona Therapeutics | , | Liquidating Jan 2019 |
| Hycor Biomedical | Garden Grove, CA | In-Vitro Diagnostics |
| EpiBiologics | San Mateo, CA | Bispecific Antibody |
| ANI Pharmaceuticals | Baudette, MN | Generics, Contract Manufacturing |
| Viatar CTC Solutions | , | Gone Jun 2019 |
| Warburg Oncology | , | Renamed Solid Therapeutics |
| Enodar BioLogic | , | Gone, Jun 2014 |
| Crystal Pharmatech | Suzhou, China | Contract research - materials science and engineering for drug development |
| Curamys | , | Website down Dec 2024 - Apr 2025 |
| KinDex Pharmaceuticals | , | Website down Jul 2021 - Dec 2021 |
| VALOS | Genova, Italy | Clinical Statistics |
| River Vision Development Corp | , | Acquired by Horizon Pharma, May 2017, $145M |
| Teva | West Chester, PA | Small Molecules |
| |
Mississauga, ON | Eurofins CDMO Alphora (Mississauga) delivers small molecule & biologics drug development and manufacturing, from preclinical to commercial stages. |
| PhaseBio Pharmaceuticals | , | Shut down Feb 2023; Bankruptcy filed Oct 2022, lead sold Jan 2023 |
| LaNova Medicines | Shanghai, China | Cancer Targeting Antibodies |
| Belcher Pharmaceuticals | Largo, FL | Generic Development |
| Split Biosciences | , | Renamed Parse Biosciences, Jan 2021 |
| Stada | Bad Vilbel, Germany | Generics |
| Roowin | Riom, France | Chemical Synthesis |
| CaPtivate Pharmaceuticals | Doylestown, PA | Calcium Phosphate Nanoparticle vaccine adjuvant/delivery system |
| EAG Laboratories | East Windsor, NJ | Analytical & Synthesis Services |
| Biomendics | Rootstown, OH | Rare Dermatologic Disorder Treatment |
| Medical Device Usability | , | Acquired by UL, 2018 |
| Frontage | Exton, PA | Contract Research & Development, Clinical Services, CMC Services |
| Lectus Therapeutics | , | Sold off product |
| ZyMot fertility | , | Acquired by CooperSurgical, Jun 2024 |
| PolyPeptide Group | Thane, India | Polypeptide Manufacturing |
| Isotechnika | , | Acquired and merged with Aurinia, Sep 2013 |
| West-Ward | , | Now part of Hikma |
| UTAK Laboratories | Valencia, CA | Quality Controls |
| , | Website down Aug 2025 - Jan 2026 | |
| PhosImmune | , | Acquired by Agenus, Dec 2015, up to $45M |
| SPR Therapeutics | Cleveland, OH | Nerve Stimulation Therapy |
| Jivana Biotechnology | , | Website down Oct 2021 - Feb 2022 |
| Advanced Cell Diagnostics | Newark, CA | RNA Detection |
| Palmaz Scientific | , | Bankrupt, 2016 |
| Diomics | , | Website taken over by roofers, Sep 2022 |
| Emeryville Pharmaceutical Services | , | Rebranded as Emery Pharma |
| Eppendorf | Jülich, Germany | Wide Range of Scientific Products |
| Mytide Therapeutics | , | Website gone Feb 2024 - Jun 2024 |
| Circulogene Theranostics | Birmingham, AL | Diagnostic for clinically significant tumor DNA/RNA alterations |
| MIODx | , | Website down Jul 2022 - Aug 2022 |
| AerWave Medical | , | Filings late Apr 2024; No news Apr 2023 - Sep 2025 |
| Tremeau Pharmaceuticals | Concord, MA | Non-opioid pain therapies |
| Teres Bio | , | Website down May 2023 - Dec 2023 |
| Amgen | Rotkreuz, Switzerland | Small Molecules, Biologics |
| Nuvectra | , | Filed Chapter 11 bankruptcy, Nov 2019 |
| ATVIO Biotech | , | Merged with Orgenesis Biotech |
| Gnome Diagnostics | , | Renamed Gnome Sciences |
| Aphena Pharma Solutions | Easton, MD | Pharmaceutical Packaging |
| mEDICORENT | Solna, Sweden | Clinical Outsourcing & Recruitment |
| PAN-Biotech | Aidenbach, Germany | Media, Reagents, Buffers |
| bioCSL | , | Combined with Novartis vaccine unit to become Seqirus |
| Verismo Therapeutics | Philadelphia, PA | Cell Therapy |
| Volu-Sol | Salt Lake City, UT | Sample Stains |
| Iquum | , | Acquired by Roche, Apr 2014 |
| 3PrimeDx | , | No website Nov 2018 - Mar 2020; SBIR grant |
| MantaBio | Beverly, MA | Real-time PCR System |
| Optical Imaging | , | Website taken over, Mar 2019 |
| Coqui RadioPharmaceuticals | , | Website down Oct 2024 - May 2025 |
| Orca Pharmaceuticals | , | Website gone Jun 2020 - Oct 2020 |
| Orthogonal Biologics | , | Acquired by Cyrus Biotechnology, Dec 2021 |
| Biotika | Slovenská, Slovakia | APIs, Contract Manufacturing |
| CellTherapies | Melbourne, Australia | Cellular Therapies |
| Trubion Pharmaceuticals | , | Acquired by Emergent BioSolutions Aug 2010, $97M |
| XenoGesis | , | Acquired by Sygnature Discovery, Oct 2020 |
| NanoCarrier | , | Renamed NANO MRNA, Jul 2023 |
| Cutis Diagnostics | , | Renamed BakoDx, educational services and sales platform |
| Skny Pharmaceuticals | , | Acquired by Mira Pharmaceuticals, May 2025 |
| Synteract | , | Website down May 2022 - Oct 2022 |
| BioConsulting International | , | Ancient website, presumed defunct |
| Genetic Signatures | Newtown, Australia | Real-time PCR kits for infectious diseases |
| BeBetter Med | Waltham, MA | siRNA Therapeutics |
| HiTech Health | Spidéal, Ireland | Biopharm CDMO |
| Binx Health | Trowbridge, UK | Medical, Consumer Diagnostics |
| Cumulus Neuroscience | Belfast, UK | Neuro Data Platform |
| Entopsis | , | Acquired by PanGIA Biotech, Feb 2025 |
| Singleron Biotechnologies | Nanjing, China | Single-Cell Sequencing, Service Lab |
| Arujet Pharmaceuticals | , | Consultancy with website copyright 2009 as of 2020 |
| Medimetrics | , | Assets acquired by Progenity, Sep 2019 |
| Aryastha Life Sciences | Hyderabad, India | Drug Discovery Contract Work |
| |
Aurengabad, India | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Xiros | Leeds, UK | Implantable textile-based orthopedic devices for ligament, tendon, and soft tissue repair |
| , | Website down Nov 2025 - Jun 2026; fka Allora Diagnostics; fka Avisa Pharma | |
| Avatar Biotechnologies | , | Gone 2010 |
| Variant Pharmaceuticals | , | Renamed ZyVersa Therapeutics, May 2019 |
| Treximo | , | Merged with ProPharma, Sep 2021 |
| ConsoneAI | Wetherby, UK | AI-Powered Toxicity Prediction for Drug Development |
| Embolx | Sunnyvale, CA | Microcatheters for arterial embolization procedures |
| YishengBio | , | Now YS Biopharma |
| Montis Pharmaceuticals | , | Bought by SuperGen, Apr 2006 |
| Sunstone BioSciences | , | Acquired by Intelligent Material Solutions, 2010 |
| Vicgene | , | Website looks ridiculous, copyright 2005 |
| TetraLogic Pharmaceuticals | , | Sold Assets, everyone resigned, stock delisted, Dec 2016 |
| PathoQuest | Paris, France | Diagnostic, Pathogen detection |
| Biofortuna | Deeside, UK | Freeze-Dried PCR Reagents, Diagnostics |
| Rex Medical | , | Employees all left, Linkedin page gone as of Nov 2023 |
| CHEM-X-INFINITY | , | Website gone Nov 2017 |
| TeraPore Technologies | South SF, CA | Membrane Technologies |
| Rithim Biologics | Woodbine, MD | Gene Therapy for Tachycardias |
| Sekisui Diagnostics | Burlington, MA | Diagnostics |
| Adept Therapeutics | , | No website Mar 2024 - Jun 2025 |
| DNAe | London, UK | Next-gen Sequencing |
| Mystic Pharmaceuticals | , | Renamed Zeteo Biomedical, 2023? |
| Cytex Therapeutics | , | Renamed CytexOrtho, Jun 2022 |
| Minimally Invasive Devices | , | Shut down |
| QC Ware | Palo Alto, CA | Molecular Discovery Platform |
| CordenPharma | Plankstadt, Germany | Contract Small Molecules |
| Topaz Pharma | , | Bought by Sanofi Pasteur 2012 |
| |
Mumbai, India | Büchi AG is a globally leading Swiss manufacturer of reactor systems for the chemical and pharmaceutical industry and research institutions. |
| CardioMEMS | , | Acquired by St. Jude Medical, Jun 2015, $455M |
| NextGen Pharmaceuticals | Brooklyn, NY | OTC, Generics |
| Egalet | , | Renamed Zyla Life Sciences, May 2019 |
| Elsie Biotechnologies | , | Acquired by GSK, Jun 2024, up to $50M |
| Celsense | , | Shut down Dec 2021 |
| Tolera Therapeutics | , | Older Url for sale, newer url now for sale Dec 2019 |
| Placon Therapeutics | , | No website Mar 2019 - Aug 2020; MA-based |
| The Adult Stem Cell Technology Center | , | Changed name to Asymmetrex, 2014 |
| Svar Life Science | Malmö, Sweden | Diagnostics |
| Teleflex Medical | Tokyo, Japan | Surgical and Medical Devices |
| ActiveSite Pharmaceuticals | , | Ancient Website, not registered in CA Jun 2019 |
| Tularik | , | Bought by Amgen, Mar 2004, $1.3B |
| GeoVax | Smyrna, GA | Vaccines |
| Artidis | Basel, Switzerland | Personalized Diagnostics |
| Libertas Pharma | , | Acquired by Mayne Pharma, Jul 2013 |
| NanoCytomics | Evanston, IL | Optical imaging for cancer detection |
| Xentria | Chicago, IL | Biologics & Biosimilars, Monoclonal Antibody |
| Galaxy Biotech | , | Shut down Feb 2008 |
| Vala Sciences | San Diego, CA | Cell Image Analysis |
| MDX Lifesciences | , | Seems gone Jul 2022; Not registered as a business in MA, Apr 2019 - Mar 2020 |
| Daiichi Sankyo | Fukoroi, Japan | Small Molecules |
| Innovative Med Concepts | , | Renamed Virios Therapeutics, Aug 2020 |
| , | Renamed Cyaris, Apr 2026 | |
| |
Pisgah Forest, NC | Onyx Scientific provides process chemistry (PR&D), analytical and solid state services, non-GMP scale up and GMP manufacturing (phase I to commercial) |
| ClonOrgan | Chengdu, China | Xenotransplantation |
| Optimata | , | Shut down May 2019 |
| VSPharmTech | Seoul, Korea | Small Molecules for Cancer |
| , | Renamed Helus Pharma, Jan 2026 | |
| NovaXS Biotech | , | Founders gone Sep 2023 |
| AB BioTechnologies | , | Renamed Labyrinth BioPharma |
| Pevion Biotech | , | Gone, 2-19-14 |
| Kenta Biotech | , | Assets acquired by Aridis Pharmaceuticals, May 2013 |
| Spiden | , | Renamed Liom, Jul 2024 |
| Element | Concord, CA | Global life sciences services. Benefit from CDMO, CRO, analytical, and central lab support. |
| Creative Bioarray | Shirley, NY | Tissue & Cell Research Products |
| Inteprod | Eagleville, PA | Diagnostic Manufacturing |
| , | Website down Oct 2025 - Jan 2026 | |
| Ferrosan | Søborg, Denmark | Surgical hemostatic products and medical devices |
| Assay Designs | , | Now Enzo Life Sciences |
| Werfen | Barcelona, Spain | Hemostasis Lab Systems, Reagents, Diagnostics, Antibodies |
| TheraBiologics | , | Seems to be shut down 2019; website gone Jan 2021 |
| Naurex | , | Acquired by Allergan, Jul 2015, $560M + milestones |
| EKF Diagnostics | Cardiff, UK | Diagnostics |
| Inhibox | , | Renamed Oxford Drug Design, May 2017 |
| Altasciences | Cypress, CA | Contract Research |
| Mirabilis Medical | , | Website down Feb 2021 - Apr 2021 |
| Galena Biopharma | , | Acquired via Reverse Merge by Sellas Life Sciences, Aug 2017 |
| Anayaderm | , | Acquired by Alexar Therapeutics, 2014 |
| NextGen Laboratories | , | Website gone Jun 2024 - Aug 2024 |
| Regulatory Heights | , | Website down Oct 2021 - Jul 2022 |
| AKRN Scientific Consulting | , | Acquired by NAMSA, Mar 2022 |
| , | Acquired by Maverix Medical, Dec 2023 | |
| , | Website down Jan 2026 - May 2026 | |
| Muna Therapeutics | Frederiksberg, Denmark | Neurodegenerative Therapeutics |
| Medelis | Thompson's Station, TN | Clinical Research |
| Antigen Labs | , | Closed 2014, Products seemingly acquired by Greer |
| Mononuclear Therapeutics | Hong Kong, China | Mononuclear Cell Therapies |
| Cellzome | , | Acquired by GSK Mar 2012 |
| Sygene Technologies | , | Website gone Nov 2018 |
| Oncofactor | , | Gone 2016 |
| Genome Liberty | , | Shut down Jul 2015, left door open to return upon FDA DTC genetic testing clarity |
| PreOmics | Planegg-Martinsried, Germany | Sample prep for proteins, peptides and proteomic analysis by MS |
| Angel Pharmaceuticals | Zhejiang, China | Small Molecules, Biologics |
| Multitude Therapeutics | Shanghai, China | Antibody Discovery Arrays, ADCs |
| EAG Laboratories | Tokyo, Japan | Analytical & Synthesis Services |
| Charles River Laboratories | Malvern, PA | Biologics development, R&D, and testing |
| Ariston Pharmaceuticals | , | Merged into Manhattan Pharmaceuticals, Mar 2010 |
| iNtRON Biotechnology | Gyeonggi, Korea | Diagnostics & Biologics |
| Incyton | Planegg, Germany | Cell Analysis Platform |
| Carolina BioPharm | , | Website Gone Dec 2013 |
| Wize Pharma | , | Website down Jul 2022 - Nov 2022; fka Ophthalix |
| Medtronic | Minneapolis, MN | Medical Devices |
| 54gene | , | Website down Jul 2023 - Dec 2023 |
| , | Acquired by Revance, Feb 2025; fka Bellus Medical | |
| Gen9 Bio | , | Bought by Ginkgo Bioworks, Jan 2017 |
| Ichor Life Sciences | Lafayette, NY | Contract Small Molecules, Biologics, Animal Studies |
| Pfizer | Andover, MA | Small Molecules, Vaccines, Biologics |
| Therazyne | Daejeon, Korea | Computational protein design and molecular interaction prediction |
| ICB International | , | No news 2021 - Aug 2025; LI page gone Nov 2023; Business filings late Sep 2022 |
| RetiSpec | Toronto, ON | Retinal Scanning for Diagnostic Purposes |
| Translumina | Hechingen, Germany | Cardiovascular Devices |
| InSCREENeX | Braunschweig, Germany | Engineered Research Cells |
| In Vivo Medical Diagnostics | , | Changed name to In Veritas Medical Diagnostics, Apr 2005 |
| Zenosense | , | No website, shell company Nov 2020 |
| Orpheris | , | Subsumed into parent Ashvattha Therapeutics |
| GenKOre | Seoul, Korea | Gene-editing therapies |
| Dokumeds | , | Acquired by Rho, Dec 2021 |
| OrthoGrid | , | Acquired by Zimmer Biomet, Aug 2024 |
| Companion Diagnostics | , | Site gone Mar 2017; Entered bankruptcy Sep 2014; relocated from CT to IN in 2010 |
| Viant Medical | Bacup, UK | Contract Medical Devices |
| , | Website down Aug 2025 - Dec 2025 | |
| Clontech | , | Now Takara Bio |
| Chiesi USA | Cary, NC | Small Molecules, Biologics, Orphan Drugs |
| Nova Pharmaceuticals | , | Acquired by Galera Therapeutics, Dec 2024 |
| Leukemia Therapeutics | , | Professor solo side project; MA business filings late, Jun 2024 |
| Macrobian-Biotech | , | Website gone May 2025 - Sep 2025 |
| Sommetrics | San Diego, CA | Sleep Improvement Technology |
| TissueVision | Newton, MA | Biomedical Imaging & Tissue Processing |
| Gensignia | , | Website Gone, Aug 2017 |
| FIZE Medical | Modi'in, Israel | Real Time Urine Output Data |
| Genoskin | Salem, MA | ex vivo Clinical Testing |
| Sonosine | Kidlington, UK | Medical Imaging |
| SocraTec R&D | Erfurt, Germany | Clinical Development Servies |
| Olympia Diagnostics | , | Website gone Feb 2023; not registered business in CA |
| CATO SMS | , | Renamed Allucent, May 2022 |
| OncoMax | , | No news since 2013 as of Oct 2019 |
| Ercole Biotech | , | Acquired by AVI Biopharma 2008 |
| Akribion Genomics | , | Renamed Akribion Therapeutics, Jan 2025 |
| Leman Biotech | Shenzhen, China | AI-enabled metabolic cancer immunotherapy |
| Brain Vision | Morrisville, NC | EEG Systems |
| NAT Diagnostics | , | Acquired by Becton-Dickinson, May 2020 |
| Lerna Biopharma | , | Website down Feb 2025 - Jul 2025; fka Cargene Therapeutics & Cargene Biopharma |
| , | Renamed Hubot, May 2026 | |
| Minntech | , | Now Medivators |
| Alpine Immune Sciences | , | Acquired by Vertex Pharmaceuticals, May 2024, $4.9B |
| Activate Immunotherapy | , | Dissolved Sep 2016; fka NovaRX |
| Signal Genetics | , | Merged with Miragen Therapeutics, Nov 2016, Took Miragen name |
| Phrixus Pharmaceuticals | , | Shut down 2019 |
| NxStage | , | Acquired by Fresenius Kabi, Feb 2019, $2B |
| ReXceptor | , | No website Dec 2019 - May 2023 |
| Avail Medsystems | , | Tech sold Mar 2024 |
| Gemini Therapeutics | , | Merged with Disc Medicine, Jan 2022 |
| Mauna Kea Technologies | Paris, France | Digital in-vivo endomicroscopy |
| Flower Orthopedics | , | Website down Oct 2022 - Mar 2023; Acquired by Conventus Orthopedics, took name |
| Igenomix | São Paulo, Brazil | Contract genetic testing for reproductive health; covid-19 pcr |
| Sirnaomics | Suzhou, China | RNAi Therapeutics |
| NanoBio | , | Renamed BlueWillow Biologics, May 2018 |
| ViaNautis Bio | Cambridge, UK | Genetic Nanomedicine Delivered Intracellularly |
| Autobahn Therapeutics | San Diego, CA | Remyelination program for multiple sclerosis |
| Adjuvance Technologies | , | Website down Jul 2022; Trying to find buyer, Let go of most employees, Feb 2022 |
| Avidity Biosciences | San Diego, CA | Antibody-Oligonucleotide Conjugates |
| NP Medical | Clinton, MA | Fluid management devices for infusion therapy and vascular access |
| Transcriptic | , | Merged with 3Scan to become Strateos, Jun 2019 |
| Emmaus Life Sciences | Torrance, CA | Oral amino acid treatment |
| Genopis | , | Acquired by Wacker Feb 2021 |
| Lidco | , | Acquired by Masimo, Feb 2021 |
| , | Bankruptcy, Nov 2025; Website down Oct 2025 - Dec 2025 | |
| Finvector Vision Therapies | Kuopio, Finland | Viral-Based Gene Therapy |
| Core Diagnostics | Gurgaon,, India | Comprehensive Clinical and High-End Diagnostics |
| Cirrus Bio | , | Acquired by Maverix Medical, Mar 2024 |
| Siegfried | Saint Vulbas, France | Contract Drug Manufacturing, APIS, Development |
| Paragon BioTeck | , | Acquired by Bausch + Lomb, Feb 2023 |
| , | Acquired by Inari Medical, Nov 2023, $250M + $165M milestones | |
| DiscoveryBioMed | , | Acquired by eurofins, Jul 2022 |
| Global Pharma Tek | Edison, NJ | Contract Research, Clinical Research, Consulting |
| G1 Therapeutics | , | |
| Convergen LifeSciences | , | Renamed Genprex |
| Tercica | , | Bought by Ipsen, Oct 2008 |
| AlcaSynn | , | Renamed ChironWells |
| Cutting Edge Therapeutics | , | Website under construction since 2011 |
| Genmab | Plainsboro, NJ | Biologics |
| Bioinformatics CRO | Orlando, FL | Customized computational biology services |
| Inimmune | Missoula, MT | Immunotherapeutics |
| Accuri Cytometers | , | Acquired by BD, Mar 2011 |
| VGX Pharmaceuticals | , | Merged with Inovio |
| InstruNor | , | Acquired by Fluidigm, Feb 2020 |
| Rayner Intraocular Lenses | Worthing, UK | Intra-Ocular Lenses |
| Copan Diagnostics | Murrieta , CA | Specimen Processing, Digital Microbiology |
| Perimeter Medical Imaging AI | Toronto, ON | Cancer Surgical Margin Identification |
| Sol-Gel Technologies | Ness Ziona, Israel | Silica-based delivery system |
| Clarix Imaging | Chicago, IL | 3D Specimen Imaging |
| Arrogene | , | Website down Sep 2023 - Mar 2024 |
| Retrogenix | , | Acquired by Charles River Labs, Mar 2021 |
| Pharmaceutical Machine Services | , | Gone Oct 2018 |
| Indero | Montréal, QC | Dermatology Clinical Research |
| Epigenetix | , | No annual report filed 2013-2019 |
| EndoQuest Robotics | Houston, TX | Microsurgical Robotic Devices |
| Terumo Medical | Somerset, NJ | Medical Devices |
| Aldagen | , | Bought by Cytomedix Feb 2012 |
| Phage Pharmaceuticals | , | Website Gone 2-22-14 |
| Aarti Pharmalabs | Mumbai, India | CDMO - APIs, Biologics |
| Ziphius Vaccines | Merelbeke, Belgium | Self-amplifying RNA Vaccine |
| A2i Therapeutics | , | Website down Jul 2023 - Dec 2023; Not sure if working on drugs in-house |
| Orinove | , | Seems gone as of 2019; No website Oct 2019 - Aug 2021 |
| Mepsgen | Seoul, Korea | Lab-on-a-Chip |
| AOP Orphan Diseases | Budapest, Hungary | Orphan disease treatments |
| AMR Clinical | Knoxville, TN | Clinical Sites, Recruiting |
| VERIGRAFT | Gothenburg, Sweden | Personalized Tissue Transplants |
| MicuRx Pharmaceuticals | Foster City, CA | Antibiotics |
| CMAX Clinical Research | Adelaide, Australia | Clinical Research |
| Becton Dickinson | Sparks, MD | Various medical devices and health products |
| Vicinivax | , | Clinical trial in 2016, nothing from then until 2023, no one on LI with company May 2023 |
| PhageVax | , | 2009 Press Release is only content on entire website, Dec 2019 |
| Pulmatrix | Bedford, MA | Inhalable Aerosols |
| Laureate Pharma | , | Acquired by Gallus |
| Applied Immunology | , | Acquired by Precision for Medicine, May 2016 |
| Expedition Medicines | Cambridge, MA | Generative Design of Small Molecules |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Advaite | , | Website down Jan 2024 - Aug 2024 |
| Cancer Targeted Technology | Woodinville, WA | Small molecular weight enzyme inhibitors; imaging and drug delivery |
| Amador Bioscience | Germantown, MD | Consulting, Lab Service, Clinical Trial Management |
| Heraeus Medical | Cartago, Costa Rica | Medical Devices |
| CP Life Science | , | Split and became Medvacon |
| Curadev | Kent, UK | Immuno-oncology |
| Teleflex Medical | Belp, Switzerland | Surgical and Medical Devices |
| Myraqa | , | Acquired by Illumina Jul 2014 |
| Eleven Therapeutics | Tel Aviv, Israel | Small interfering RNAs with ultra-long durability by utilizing high throughput combinatorial chemistry and AI |
| Flarebio Biotech | , | Renamed Cusabio Technology |
| Intelligent Biosystems | , | Acquired by Qiagen, Jun 2012 |
| Minerva Biotechnologies | Waltham, MA | Cancer therapeutics, Stem Cells |
| Normonz Pharmaceuticals | , | Website down Dec 2023 - May 2024 |
| Macular Therapeutics | , | Website down Nov 2022; Not registered in MA, Dec 2021 - Sep 2022 |
| Virco | , | Bought by J&J |
| CG Therapeutics | , | Dissolved Jul 2013 |
| Palladio Biosciences | , | Website down Jul 2022 - Nov 2022 |
| On-X Life technologies | , | Acquired by CryoLife, Jan 2016, $130M |
| MilliporeSigma | Carlsbad, CA | Clinical Manufacturing |
| Envoy Medical | White Bear Lake, MN | Implanted hearing device |
| Auristone | Singapore, Singapore | Personalized Medicine Through Epigenomics |
| NanoMosaic | Waltham, MA | Nanoneedle-powered protein screening |
| Ciba-Geigy | , | Merged with Sandoz to create Novartis |
| Akers Biosciences | , | Acquired by MyMD Pharmaceuticals via Reverse Merger, Nov 2020 |
| MyoPax | Berlin, Germany | Cell & Gene Therapies |
| Pfizer | La Jolla, CA | Peptides, Monoclonal Antibodies |
| Ambrilia Biopharma | , | Bankrupt 2011 |
| Arthrosi Therapeutics | San Diego, CA | Treatments for gout and chronic kidney diseases |
| Navigenics | , | Acquired by Life Technologies 2012 |
| Anacor Pharmaceuticals | , | Bought by Pfizer, Jun 2016, $5.2B |
| EBR Systems | Sunnyvale, CA | Wireless Cardiac Stimulation |
| Viscus Biologics | Cleveland, OH | Allograft and xenograft devices |
| Advanced Life Solutions | Chavannes Sur Reyssouze, France | Organ Preservation Technology |
| OrbusNeich | Hong Kong, China | Medical Devices for Vascular Diseases |
| Pfizer | Dalian, China | Small Molecules, Biologics, Vaccines |
| EchoNous | Redmond, WA | Ultrasound device, bladder scanner |
| Catalent | Kansas City, MO | Catalent Pharma Solutions – BioAnalytics is a global CDMO providing GMP analytical solutions across all modalities from Discovery through Commercial activities for biologics. |
| Miromatrix | Eden Prairie, MN | Organs for Implant |
| SIMR Biotech | Shanghai, China | CNS Small Molecules |
| Veeva Systems | Toronto, ON | Life Science Software |
| CapCell Biologics | , | Website down Sep 2021 - Feb 2022 |
| Carbogen Amcis | Aarau, Switzerland | Drug Development & Commercialization |
| Michelson Diagnostics | Maidstone, UK | Non-melanoma skin cancer diagnosis |
| Nextera | Oslo, Norway | Combinatorial libraries of peptide HLA class II repertories enabling novel target discovery |
| Target Therapeutics | , | Bought by Boston Scientific, Jan 1997 |
| LGC Biosearch Technologies | Middlesex, UK | Custom Oligos, Reagents, Genomic Analysis |
| LI-COR Biosciences | Lincoln, NE | Near-infrared (NIR) fluorescence quantitation |
| Pear Bio | Natick, MA | Cancer Treatment Selection |
| Neurocrine Biosciences | San Diego, CA | Small Molecules |
| Alere | , | Acquired by Abbott, Oct 2017, $4.6B |
| BioNTech | Idar-Oberstein, Germany | mRNA, Vaccines, Biologics |
| C-Ray Therapeutics | Chengdu, China | Radiopharmaceuticals |
| Getinge | Hechingen, Germany | Medical Technology |
| TCR2 Therapeutics | , | Merged with Adaptimmune, Jun 2023 |
| , | Website down Oct 2025 - Jan 2026 | |
| CoLucid Pharmaceuticals | , | Acquired by Lilly, Jan 2017, $960M |
| PhotoSonix Medical | , | Now a licensing outift |
| Audeo Oncology | , | Alchemia spinout, not sure if ever actually hit the ground, marked as closed on Google Dec 2019 |
| Biojo Sciences | Bethesda, MD | Gene Therapy & Others |
| BluDiagnostics | , | Website down Aug 2020 - Feb 2021 |
| Hummingbird Bioscience | Singapore, Singapore | Antibody Development Platform |
| NephroSant | , | Website down Aug 2023 - Feb 2024 |
| Antares Pharma | , | Acquired by Halozyme, May 2022, $960M |
| Otolith Labs | Washington, DC | Wearable for Vertigo |
| Concuir Consulting | Laguna Hills, CA | Management Consulting - Program and project management, project strategy and delivery, change management, quality, remediation consulting. |
| Umlaut.bio | Wilen bei Wollerau, Switzerland | Therapeutic molecules to modify tRNA and target cancers and inflammatory diseases |
| Cellular Vehicles | San Mateo, CA | Process automation platform for cell and gene therapies |
| Chugai Pharma | Tokyo, Japan | Small Molecules |
| Ohm Laboratories | , | Owned by Ranbaxy, then Sun Pharma |
| ApniCure | , | Gone 2017 |
| Recursion Pharmaceuticals | Salt Lake City, UT | Automated, software-based drug discovery |
| QLB Biotherapeutics | , | Shut down Feb 2021 |
| CATLab - Accredited Calibration Laboratories | , | Acquired by Trescal, Jan 2022 |
| Intica Biomedical | , | Bankrupt 2014 |
| Accellacare | Ames, IA | Clinical Research |
| Macrochem | , | Acquired by Access Pharmaceuticals, Feb 2009 |
| Sirtex Medical | Bonn, Germany | Cancer Treatments |
| Unetixs Vascular | Warwick, RI | Non-invasive vascular diagnostics |
| , | Website down Jul 2025 - Dec 2025 | |
| Onkos Surgical | Parsippany, NJ | Surgical Devices |
| Trince | Gent, Belgium | photoporation-based transfection platforms and nanoparticles |
| Senores Pharmaceuticals | Ahmedabad, India | Complex Generics |
| Resonetics | Montreal, QC | Contract Medical Device Manufacturing & Development |
| G&L Scientific | , | Renamed G&L Healthcare Advisors, Jan 2023 |
| CoreRx Inc. | , | Merged into Bend Bioscience, Sep 2024 |
| |
Uithoorn, Netherlands | Rapid Novor is an antibody discovery and characterization CRO, employing advanced mass spectrometry to achieve unparalleled precision. |
| Resilio Therapeutics | , | Shut down Jan 2024 |
| Digital Diagnostics | Coralville, IA | autonomous AI diagnostic system |
| Terpenoid Therapeutics | , | Gone |
| Okeiro | Paris, France | Digital tools for organ transplant and chronic disease management |
| Biotec Pharmacon | , | Renamed ArcticZymes, Jun 2020 |
| Fero Industries | , | Restructured, renamed PharmaRoth Labs, Jul 2012 |
| Sophiris Bio | , | Shut down May 2020 |
| Aravive Biologics | , | Liquidated Jan 2024; fka Ruga; went public via merger with Versartis subsidiary |
| Meribel Pharma Group | Pessac, France | Contract Manufacturing |
| Enochian Biopharma | , | Acquired by DanDrit Biotechnology, Feb 2018 |
| ACGT Progenomics | Wheeling, IL | DNA Sequencing Services |
| Numaferm | Düsseldorf, Germany | Recombinant Protein Production |
| Atlas Therapeutics | , | Changed name to Myos Corp May 2012 |
| nitec Pharma | , | Merged with Horizon Pharma |
| Chimerx | , | Last news 2013, website © 2015, not in WI business registry |
| BioPhyZica | , | Gone 2016 |
| Arete Therapeutics | , | Out of Business |
| Merit CRO | Madison, WI | Imaging management and analysis services for ophthalmic clinical and preclinical studies |
| Prana Biotechnology | , | Renamed Alterity Therapeutics, Apr 2019 |
| Genetic Systems | , | Bought by Bristol-Myers, 1986 |
| Fina Biotech | Pozuelo de Alarcon, Spain | Kit to determine degree of DNA fragmentation in human sperm; non invasive assay for bladder cancer diagnosis |
| Bioenza | , | Website gone Sep 2017 |
| Luciole Medical | Zurich, Switzerland | Cerebral Monitoring |
| Point Biomedical | , | Liquidated Jul 2008 |
| Althea Technologies | , | Acquired by Ajinomoto, Mar 2013 |
| Nexgenia | , | Gone Dec 2019 |
| Viralgen | San Sebastián, Spain | cGMP Gene Therapy Manufacturing |
| Silktap | , | Liquid silk. Site gone |
| TUBE Pharmaceuticals | , | Website gone May 2025; Acquired by Oncamatryx, May 2023 |
| Devoro Medical | , | Acquired by Boston Scientific, Sep 2021, $320M + $80M Milestones |
| Atritech | , | Bought by Boston Scientific, Mar 2011, $100M + $275 milestones |
| Armata Pharmaceuticals | Los Angeles, CA | Natural and synthetic bacteriophage-based therapies |
| Fornax Biotech | , | Dissolved Jun 2021 |
| Cell Culture Service | , | Acquired by Evotec, Jan 2013 |
| Nobias Therapeutics | Philadelphia, PA | AI/ML Drug Discovery |
| Spirovant Sciences | Philadelphia, PA | Gene Therapy - Lung Diseases |
| Neolys Diagnostics | Entzheim, France | Cancer Diagnosis |
| Form Bio | Dallas, TX | Computation Life Sciences Platform |
| Zoll | Roseville, MN | Medical Devices, Defibrillators |
| Advanced Bifurcation Systems | Livermore, CA | Bifurcating Stent |
| Vertera Spine | , | Bought by NuVasive, Sep 2017 |
| Gilead | Mississauga, ON | Small Molecules |
| Restorgenex | , | Merged with Diffusion Pharmaceuticals, Dec 2015 |
| Penumbra | Alameda, CA | Vascular / Surgical Devices |
| Darwin Life | , | Seems gone, Website down Jan 2024 - Jul 2024 |
| Catawba Research | Charlotte, NC | Clinical Research |
| SkyePharma | Saint-Quentin-Fallavier, France | CDMO |
| Selecta Biosciences | , | Merged with Cartesian Therapeutics, Nov 2023 |
| Waters | Milford, MA | Chromatography & Chemistry |
| Essential Therapeutics | , | Changed Name to Trine Pharmaceuticals 2004 |
| KeChow Pharma | ZZ, China | Small Molecules and others |
| Alcon | Houston, TX | Eye-Care Products |
| OncoC4 | Rockville, MD | Antibodies, Immunotherapies |
| Perlstein Lab | , | Renamed Perlara PBC, Oct 2016 |
| Scion Medical Technologies | , | Gone 2016 |
| Regulatory Professionals, Inc. | , | Acquired by Premier Research, Jul 2018 |
| AbbVie | Cork, Ireland | Contract Manufacturing |
| 2KMM | Katowice, Poland | CRO services and eClinical solutions with global reach |
| Accuprec Research Labs | Ahmedabad, India | Contract Research, Device Testing |
| Symic Biomedical | , | Seems gone as of Dec 2019 |
| Kite Pharma | El Segundo, CA | Engineered Autologous T Cell Therapy, CAR-T |
| MiCo BioMed USA | Cincinnati, OH | Microfluidic immunoassay plates, ELISA kits, molecular diagnostic devices, sample preparation systems, and point-of-care testing platforms |
| Georgiamune | Rockville, MD | Antibodies, Small Molecules |
| Salvat | Barcelona, Spain | Small Molecules |
| PRISM Biolabs | Fujisawa, Japan | Peptide-acting Small Molecules |
| Gloucester Pharmaceuticals | , | Acquired by Celgene, Dec 2009, $340M + $300M milestones |
| Getinge | Englewood, CO | Medical Technology |
| Recipharm | Zwickau, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| , | Website down Jul 2025 - Jan 2026 | |
| Aspen Medical products | Irvine, CA | Upper and lower spinal orthotics |
| Bridgehead International | , | Bought by Gfk, Mar 2012 |
| Arterex | Milpitas, CA | Medical Device Manufacturing |
| Teleflex Medical | Beijing, China | Surgical and Medical Devices |
| Okairos | , | Acquired by GSK, May 2013 |
| ABANZA | Mutilva Alta, Spain | Soft Tissue Fixation |
| Bavarian Nordic | Martinsried, Germany | Vaccines |
| Asymchem | Tianjin, China | CDMO providing fully integrated solutions in small molecule drug development & production from clinical stage to commercialization |
| inVentiv Health Clinical | , | Merged with INC Research, May 2017, renamed Syneos Health |
| Talent Biotechs | , | Bought by Kalytera Therapeutics, Mar 2017, $10M + $20M milestones |
| Questcor Pharmaceuticals | , | Acquired by Mallinckrodt, Aug 2014 $5.8B |
| TenX BioPharma | , | Asset acquired 2011, seem defunct |
| Veeva Systems | Tokyo, Japan | Life Science Software |
| Mercury Pharmaceuticals | , | Website gone, strange urls, not sure what's going on |
| Digestome Therapeutics | , | Renamed Viage Therapeutics |
| Navitas Life Sciences | Gaithersburg, MD | Decentralized Clinical Research, Consulting |
| Caeregen Therapeutics | , | Renamed Retinova Therapeutics, Mar 2025 |
| ExpressCells | , | Website down Jul 2023 - Dec 2023 |
| Integra LifeSciences | Boston, MA | Medical Devices |
| Caraco Pharmaceutical Labs | , | Bought by Sun Pharma |
| |
Skokie, IL | Vetter is a global CDMO that specializes in the aseptic filling and packaging of injectables, offering product manufacturing support from clinical development to commercialization and beyond. |
| Coeptis Therapeutics | Wexford, PA | Cell Therapy Platform for Oncology |
| Scaffold Biologics | , | Bought Aperion Assets, fka Bio Ligament, no website Dec 2018 - Aug 2021, no Tweets May 2017 - Aug 2021 |
| Arrow Therapeutics | , | Bought by AstraZeneca, Feb 2007 |
| Mikroscan Technologies | Vista, CA | Pathology Technology |
| Dendreon | Union City, GA | Autologous Cell Therapy, Contract Cell Therapy Manufacturing |
| Avrio Biopharma | , | Company was consolidated into Irvine Pharmaceutical Services |
| Plexanome | , | Gone 2018 |
| GenFleet Therapeutics | Shanghai, China | Small and Large Molecules |
| iNova Pharmaceuticals | Chatswood, Australia | OTC |
| Advanced Genetic Systems | , | Dissolved Dec 2018 |
| Isolagen | , | Reorganized as Fibrocell Science |
| Alcyone Therapeutics | Lowell, MA | Gene Therapy |
| InvitroCue | Singapore, Singapore | Cell & tissue analytics |
| Biogenes | Berlin, Germany | Antibodies |
| Atlantic Healthcare | , | Website gone Jan 2024; LI page gone Nov 2023; Acquired by SPAC via Reverse Merger Oct 2020 |
| Catalyz | , | Gone |
| Savage Medical | , | Renamed Averto Medical |
| Accutar Biotechnology | Cranbury, NJ | AI Drug Discovery |
| AgeneBio | Baltimore, MD | Neurological & psychiatric diseases |
| Crossfire Oncology | Oss, Netherlands | Inhibitors, Degrader Antibody Conjugate |
| , | Website down Oct 2025 - Feb 2026 | |
| Xpress Biologics | , | Acquired by PolyPlus, Dec 2022 |
| , | Website down Jan 2026 - May 2026 | |
| Jan Medical | , | Subsumed into Brainlab, Jun 2025 |
| ESTERN Medical | Cambridge, MA | Full Range Clinical Services |
| |
Prague, Czech Republic | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| Beam Therapeutics | Cambridge, MA | CRISPR-based drug discovery |
| Eurofins Viracor BioPharma Services | Lenexa, KS | Development solutions to pharma sponsors and CROs. |
| Analytik Jena | Tewksbury, MA | Global provider of benchtop liquid handling, automation technology, and analytical instruments. |
| Pinnaxis | Noida, India | Pharmacovigilance |
| DiscGenics | Salt Lake City, UT | Spinal Stem Cell Therapies |
| Sinclair Pharma | London, UK | Aesthetic Dermatology |
| Baudax Bio | , | Chapter 11 Bankruptcy, Feb 2024; Spun out of Recro Pharma, Nov 2019 |
| Chiralgen | , | Merged with Ontorii to form WaVe Life Sciences |
| NodThera | Philadelphia, PA | NLRP3 inflammasome inhibitors |
| JBS United | , | Renamed United Animal Health, Jan 2018 |
| PersonGen BioTherapeutics | Suzhou, China | Cell Therapies, Antibodies, Nanobodies |
| Perseus Proteomics | Tokyo, Japan | Antibody Technology |
| GAVIS PHARMACEUTICALS | , | Acquired by Lupin |
| HighPoint Therapeutics | , | Website gone Oct 2020 - Mar 2021; Unknown drug types Jan 2020 - May 2020 |
| Cogmedix | , | Subsidiary of Coghlin Companies |
| Cambrex | Edinburgh, UK | Small Molecules Research, Development & Manufacturing Services |
| , | Acquired by Glaukos, Aug 2025 | |
| PHIX Genomics | , | Website down Dec 2024 - May 2025 |
| Globus Medical | Audubon, PA | Minimally-invasive surgical tools |
| Phrontline Biopharma | Shanghai, China | Bispecific dual-payload ADCs |
| C1 Consulting | , | Acquired by Charles River, Jan 2017 |
| Flexion Therapeutics | , | Acquired by Pacira BioSciences, Nov 2021 |
| Comet Therapeutics | , | Acquired by VectIvBio, Aug 2021 |
| Genlantis | , | Acquired by AMSBIO |
| Noorik Biopharmaceuticals | , | Website problem Feb 2021 - Nov 2021 |
| Ajanta Pharma | Mumbai, India | Generics, Branded Generics |
| Opus Medical | , | Acquired By ArthroCare, Nov 2004, $130M |
| AGY Therapeutics | , | Shut down pre-Aug 2005 |
| Avalign Technologies | Warsaw, IN | Orthopedics & Surgical |
| Pleno | San Diego, CA | High-throughput machines for accelerating work in identifying new targets to aid drug development |
| MAXVAX Biotechnology | Chengdu, China | Vaccines & Adjuvants |
| Resonetics | Surrey, BC | Contract Medical Device Manufacturing & Development |
| , | Acquired by Sygnature Discovery, Feb 2026; fka Scottish Biomedical | |
| Okapi Sciences | , | Acquired by Aratana Therapeutics, Jan 2014 |
| Amerigo Scientific | Hauppauge, NY | Chromatography, ELISA, antigens, proteins, reagents, services |
| Health Advances | , | Bought by Parexel, Jan 2016 |
| Appili Therapeutics | Halifax, NS | Small molecule |
| InClinica | , | Website down Sep 2021 - Feb 2022; Person who left in Jan 2020 still on website May 2021 |
| Cyon Therapeutics | , | Bankrupt, Dec 2017 |
| IRBM | Pomezia, Italy | Drug discovery for complex peptides/SMs/mAbs; display tech, HTS, DMPK, in vivo, functional genomics |
| Climb Bio | Cheshire, UK | Treatments for neuronal Excitability Disorders |
| Vascular Technology | Nashua, NH | Surgical Devices |
| Paradigm Spine | , | Acquired by RTI Surgical, Mar 2019 |
| TeutoCell | , | Renamed Xell, 2014 |
| Ferring Pharmaceuticals | Buenos Aires, Argentina | Small Molecule Manufacturing |
| |
Vienna, Austria | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| , | part of ElevateBio; fka LifeEDIT | |
| Incisive Surgical | , | Acquired by CooperSurgical, Jan 2019 |
| MabTics | Daejeon, Korea | Antibody Therapeutics |
| Txinno Bioscience | Yongin, Korea | Cancer Therapies |
| IDL Diagnostics | Stockholm, Sweden | Diagnostics |
| Ascelegen | , | Closed |
| Amylin Pharmaceuticals | , | Bought by BMS Aug 2012 |
| CanSino Biologics | Tianjin, China | Vaccines |
| Novotech | Bangkok, Thailand | Clinical Research |
| Biolytix | Dittingen, Switzerland | Molecular & Microbiology Services |
| Oncopeptides | Stockholm, Sweden | Cancer Treatments |
| China Nuokang Biopharma | , | Merged with Kingbird, probably to get access to its ticker |
| Diploid Genomics | , | |
| Transgene | Illkirch-Graffenstaden, France | Viral Vector Therapeutics, Gene Therapy |
| Network Partners Group | Warsaw, IN | Medical Device & Pharmaceutical Consulting |
| Sound Biologics | Bothell, WA | Therapeutic Antibodies |
| Tanabe Pharma America | Jersey City, NJ | Small Molecules |
| POCARED Diagnostics | , | Website down Oct 2023 - Mar 2024 |
| ProEthic Laboratories | , | Acquired by Kowa, Sep 2008 |
| Pending AI | Cambridge, MA | AI Discovery Platform |
| Alt Bioscience | , | Now PDx Biotech |
| Azur Pharma | , | Acquired by Jazz Pharmaceuticals, Sep 2011 |
| Alpha Biopharma (2) | Shanghai, China | Small Molecules |
| , | ||
| RepRegen | , | Gone, 2014 |
| Orca Bio | Menlo Park, CA | Cell Therapy & Manufacturing |
| Apoptos | , | Acquired by Receptos |
| Nodal Therapeutics | , | Next-generation antigen-specific tolerance technology |
| GenoSafe | Evry , France | Preclinical, Regulatory, Clinical Trial Services |
| Kartha Pharmaceuticals | , | Website down Jul 2024 - Dec 2024 |
| AB ANALITICA | Padua, Italy | Sequencing products |
| Solana Biosciences | , | Acquired by Inscripta, Sep 2018 |
| Prothya Biosolutions | Brussels, Belgium | Services and plasma-derived medicinal products |
| Metrohm | Mississauga, ON | Lab Data Management Software |
| Fresenius Kabi | Louviers, France | Contract Manufacturing |
| Novonesis | Beijing, China | Enzymes |
| Epigen | , | Renamed Egenix, 2002 |
| Partek | , | Acquired by Illumina, May 2024 |
| Navinci Diagnostics | Uppsala , Sweden | Biomarker Services |
| Genexx | , | Acquired by Opko Health , Oct 2009 |
| FemtoVox | , | |
| Instil Bio | Dallas, TX | Cell Therapy |
| WCG Intrinsic Imaging | , | Acquired by WCG, Jul 2021 |
| MediaPharma | Chieti, Italy | Humanized Monoclonal Antibodies |
| Baxter | Singapore, Singapore | Medication Delivery |
| Cartesian Therapeutics | Gaithersburg, MD | mRNA-Engineered Cell Therapy |
| CoDa Therapeutics | , | Renamed Ocunexus |
| Hedera Dx | Epalinges, Switzerland | Liquid Biopsy |
| , | Acquired by BMS, May 2025, $286M; bluebird bio spinout | |
| Hyloris Pharmaceuticals | Liège, Belgium | Reformulating Therapies |
| Pfizer | Neo Psychiko, Greece | Small Molecules, Biologics, Vaccines |
| Braintree Labs | , | Bought by Sebela Pharmaceuticals, May 2018 |
| Biocode Hycel | , | Website gone |
| Constellation Pharmaceuticals | , | Acquired by MorphpSys, Jul 2021 |
| ImmVira | Shenzhen, China | Drug Delivery Vector Technology |
| Synnovation Therapeutics | Wilmington, DE | Small Molecules |
| Vista Biologicals | , | Website gone, Mar 2018; business suspended by CA |
| ImmuneMed | , | Shut Down |
| Actio Biosciences | San Diego, CA | Genetics Platform |
| SpringWorks Therapeutics | Stamford, CT | Small Molecules |
| Chanelle Pharma | London, UK | Generics |
| Pacific Biosciences | Menlo Park, CA | DNA sequencing |
| Trius Therapeutics | , | Acquired by Cubist Sep 2013 |
| Laboratories Delalande | , | Acquired by Synthélabo, 1991 |
| Imre | , | Changed name to Cypress Bioscience, 1996 |
| VascuLogic | , | Website down Jun 2023 - Sep 2023 |
| QATCH Technologies | Durham, NC | Life Science Instrumentation |
| , | Website down Jan 2026 - May 2026 | |
| MyoSyntax | , | Gone 2021 |
| Champions Oncology | Hackensack, NJ | Tumor Testing & Banking |
| Rosetta Therapeutics | , | Website gone May 2023; Website empty, Sep 2022 - Apr 2023 |
| Rafagen | , | Website redirecting to Rophibio |
| Biotrace Medical | , | Acquired by Merit Medical, Oct 2022 |
| DiscoveRx | , | Renamed Eurofins Discoverx |
| QT Vascular | , | Website gone Jan 2024 |
| Maxis Clinical Sciences | Edison, NJ | Clinical Research Consulting |
| , | Acquired by Altivera Medical, Mar 2026 | |
| Sooma | Helsinki, Finland | Development of non-invasive, portable transcranial direct current stimulation devices |
| , | Merged with Minnetronix Medical to become Forj Medical, Oct 2025 | |
| AMSBIO | Abingdon, UK | Numerous assays, reagents and lab tools of all types |
| Corgentech | , | Changed name to Anesiva Jun 2006 |
| Life Science Outsourcing | Brea, CA | Medical device contract manufacturing |
| Anagin | , | No news 2017-2024, business filings late Jun 2022 |
| Hybridize Therapeutics | Oegstgeest, Netherlands | RNA treatments for kidney disease |
| Nativis | , | Renamed EMulate Therapeutics, Mar 2019 |
| PBL Assay Science | Piscataway, NJ | Biologic Reagents, Services |
| Theravance Biopharma | South SF, CA | Small Molecules |
| Exogene Therapeutics | , | Not registered in CA as of Aug 2019 - Jun 2022 |
| tranScrip | Wokingham, UK | A specialist pharmaceutical consultancy providing strategic, therapeutic and operational services. |
| , | Website down Jul 2025 - Dec 2025 | |
| BBI Solutions | Salisbury, UK | Antibodies, Sera, Enzymes, Contract Work, etc. |
| BioPharma Services | Toronto, ON | Clinical Trial Services |
| , | Website down Jan 2026 - May 2026 | |
| Aveta Biomics | Bedford, MA | Small Molecule for Bone Disease |
| Kindeva Drug Delivery | Loughborough, UK | Drug Delivery CDMO |
| SOPHiA GENETICS | Rolle, Switzerland | Clinical Next Gen Sequencing Dry Lab Service |
| UR-1 Therapeutics | , | Renamed Urica Therapeutics |
| SynAm Vaccine | , | Gone 2017 |
| Refuge Biotechnologies | , | Website down Feb 2023, executives gone |
| Mylan | , | Merged with Upjohn, renamed Viatris |
| Boditech Med | Chuncheon-si, Korea | Immunoassay Analyzer |
| |
Greensboro, NC | Aenova | A global-scale CDMO for all common dosage forms, highly rated by customers for effective communication and strong technical & scientific competence. |
| Solace Pharmaceuticals | , | Out of business 2011 |
| LUMICKS | Waltham, MA | Dynamic Single-Molecule analysis products |
| Jitsubo | Kanagawa, Japan | Generic Peptide Drugs |
| Crownlands | San Francisco, CA | Neurodegenerative CNS Data Mapping |
| Siegfried | Zofingen, Switzerland | Contract Drug Manufacturing, APIS, Development |
| |
Cambridge, UK | Selvita | Fully-integrated CRO providing multidisciplinary support in resolving the unique challenges of drug discovery, drug development and contract testing. |
| Napp Pharmaceutical | Cambridge, UK | Small Molecules |
| CeeTox | , | Acquired by Cyprotex, Jan 2014 |
| Promega | Madison, WI | Vast Catalog of Biotechnology Products |
| Rebound Therapeutics | , | Bought by Integra LIfeSciences, Sep 2019 |
| , | No news 2021 - Jan 2026 | |
| Eyevance Pharmaceuticals | , | Acquired by Santen, Sep 2020 |
| Miltenyi Bioindustry | Bergisch Gladbach, Germany | Cell & Gene Therapy CDMO |
| Fleet Therapeutics | , | Renamed Seeker Biologics |
| Molecular Staging | , | Assets acquired by Qiagen, Mar 2017 |
| Ortho Dermatologics | , | Part of Bausch Health; fka Valeant Dermatology |
| AI Biomed | , | Acquired by Medtronic, Oct 2020 |
| Avalign Technologies | Fort Wayne, IN | Orthopedics & Surgical |
| |
Nottingham, UK | Providing a full range of drug product (CDMO) and clinical (CRO) services, Quotient Sciences is a drug development & manufacturing accelerator helping clients bring molecules to cures, fast. |
| Evergreen Medical Technologies | , | Acquired by Haraeus |
| Applied Cells | Santa Clara, CA | Cell Separation Technology |
| PacificGMP | , | Bought by Abzena, Sep 2015, $8.4M |
| Pola Pharma | , | Acquired by Sun Pharma, Jan 2019 |
| , | Acquired by NorthLinks Bio, Apr 2026 | |
| TG ImmunoPharma | , | Website down Dec 2024 - May 2025 |
| Elixir Medical | Milpitas, CA | Stents |
| Quantum Pharma | , | Acquired by Clinigen, Nov 2017 |
| Pelvalon | , | Acquired by Laborie, Oct 2021 |
| Nanotherapeutics | , | Renamed Ology Bioservices, Oct 2017 |
| Medinno Pharmaceutical Technology | Seoul, Korea | Cell Therapies |
| PRIZM Pharmaceuticals | , | Merged with Matrigen to become Selective Genetics, Jul 1998 |
| Frontage | Secaucus, NJ | Contract Research & Development, Clinical Services, CMC Services |
| VBI Vaccines | Ottawa, ON | Vaccine Development |
| Easton Pharmaceuticals | , | Website gone Apr 2020 |
| Locanabio | , | Shutting down late 2023 |
| Agilis Robotics | Hong Kong, China | Flexible robotic instruments for endoscopic surgery |
| Mozarc Medical | Minneapolis, MN | Scaling Dialysis Delivery |
| Yaso Biotechnology | , | Renamed Yaso Therapeutics |
| Otogenix | , | No CA business filings Mar 2016 - Dec 2019 |
| Genewity | Oegstgeest, Netherlands | Thymus-driven therapies for immune reconstitution |
| UroDev Medical | , | Website down Apr 2024 - Aug 2024 |
| Artificial | Palo Alto, CA | AI Lab Platform |
| Korio | Doylestown, PA | RTSM Platform |
| Calypso Biotech | , | Acquired by Novartis, Jan 2024, $250M; Spun out of Merck-Serono |
| Travere Therapeutics | San Diego, CA | Small Molecules, Biologics |
| Delenex Therapeutics | , | Bought by Cell Medica, Jul 2016 |
| Genabio Diagnostics | Bedford, MA | Home Diagnostics |
| Discovery Life Sciences | Huntsville, AL | Diagnostics |
| Acme Monaco | New Britain, CT | Medical Device Contract Manufacturing |
| MiNK Therapeutics | Cambridge, UK | Cell Therapy, CAR-T |
| Arrowhead Research | , | Renamed Arrowhead Pharmaceuticals |
| Sinotherapeutics | Shanghai, China | Generics |
| Amprion | San Francisco, CA | Brain Health Diagnostics |
| Arbor Assays | Ann Arbor, MI | Lab Assays & Reagents |
| Cerno Bioscience | Las Vegas, NV | Mass Spec Software |
| Crescendo Bioscience | , | Bought by Myriad Genetics, Mar 2014 |
| Ncardia | Leiden, Netherlands | Stem Cell-related Services & Products |
| Advanced Vision Science | , | |
| Predictive Laboratories | , | Website down Jan 2022 - Jul 2022 |
| CeQur | Luzern, Switzerland | Insulin pump |
| Pending AI | Eveleigh, Australia | AI Discovery Platform |
| Conigen Biosciences | Worcester, MA | Protein Design Platform |
| Rayto Life & Analytical Sciences | Shenzhen, China | Diagnostic Equipment |
| Pharmaron | Hertfordshire , UK | R&D Services |
| AusDiagnostics | Mascot, Australia | Multiplexed Diagnostics |
| |
San Cristóbal, Spain | Curia (formerly AMRI) is a CRO/CDMO providing discovery, development, drug substance and drug product manufacturing for small molecules and biologics across 20 global sites. |
| Lion Biotechnologies | , | Changed name to Iovance Biotherapeutics, Jun 2017 |
| Accelrys | , | Bought by Dassault, 2014 |
| Abbiotec | Escondido, CA | Research Antibodies & Peptides |
| SillaJen Biotherapeutics | Seoul, Korea | Cancer therapies |
| Mercaptor Discoveries | , | Renamed Enabled Therapeutics, Aug 2024 |
| Discovery BioMed | , | Acquired by eurofins, Jun 2022 |
| IDEV Technologies | , | Bought by Abbott, Jul 2013, $310M |
| Pharmaxis | , | Website down Jun 2024 - Nov 2024 |
| Phyxius Pharma | , | Assets acquired by Oxygen Therapeutics, Nov 2013, effectively merged |
| Medventure | , | Acquired by Helix Medical, Oct 2012 |
| Zimmer Biomet | Jacksonville, FL | Medical Implants |
| Resonetics | Hudson, WI | Contract Medical Device Manufacturing & Development |
| Freudenberg Medical | Beverly, MA | Design, development and manufacturing for medical devices, in-vitro diagnostics, minimally invasive solutions, specialty components, and biopharma tubing |
| Xilis | Durham, NC | Micro-organosphere technologies to guide precision therapy for cancer patients |
| Ardea Biosciences | , | Bought by AstraZeneca, Jun 2012, $1.26B; Closed 2018 |
| Nitto Denko Avecia | Milford, MA | Oligonucleotide Manufacturing |
| Virica Biotech | Ottawa, ON | Viral Manufacturing Technology |
| Biedermann Motech | Villingen , Germany | Development, production, and distribution of innovative implants and instruments for spinal and extremity surgery |
| Piramal | Turbhe, India | CDMO |
| , | Acquired by Instem, Jul 2025 | |
| Novo Nordisk | Hillerød, Denmark | Diabetes, obesity, liver disease and other therapeutic areas |
| metaLinear | , | Website down Feb 2022 - Jul 2022 |
| Cerbios-Pharma | Lugano, Switzerland | APIs, small & large; probiotics |
| CardioDx | , | Shutting down Jan 2019 after Medicare stopped covering product |
| Timber Pharmaceuticals | , | Assets acquired by Leo Pharma, Jan 2024; Bankrupt |
| Micrus Endovascular | , | Bought by J&J, Sep 2010 |
| Cell Line Genetics | Madison, WI | Pharmaceutical Services |
| Seagull Therapeutics | , | Website down May 2023 - Dec 2023 |
| , | Website gone Dec 2025; LI gone Nov 2023 | |
| ShouTi | , | Renamed Structure Therapeutics, Aug 2022 |
| Arrowhead Medical Device Technologies | , | No news from 2014-2021, not registered in TN |
| MJ Biopharma | Mumbai, India | Generics |
| Conventus Orthopaedics | , | Acquired Flower Orthopedics, May 2020, took name |
| NeoTX | Rehovot, Israel | Oncology Immunotherapy |
| Celldex Therapeutics | Hampton, NJ | Small Molecules, Biologics, Vaccines |
| PhosphoSolutions | , | Now part of Antibodies Inc |
| Eli Lilly | San Diego, CA | Biologics Discovery |
| Pinion Immunotherapeutics | North Bethesda, MD | mRNA Vaccine Technology |
| Westat | Rockville, MD | Clinical trial design, management, services |
| Allometra | , | Gone |
| Aerpio Pharmaceuticals | , | Changed name to Aerpio Therapeutics by Reverse Merger of some sort, Mar 2017 |
| Pharmbiotest | Grudziądz, Poland | Clinical Trial Management & Research |
| Link Immunotherapeutics | , | Shut down Aug 2024; Website down Oct 2024 - Feb 2025; Not much info Sep 2020 |
| BioMoti | , | Website down Mar 2024 - Aug 2024 |
| Indigo Pharmaceuticals | , | Website Gone. Company? Probably |
| Eurofins DiscoverX | , | Acquired by Eurofins, Jul 2017; fka Discoverx |
| ZeClinics | Barcelona, Spain | Contract Drug Discovery Research using Zebrafish Models |
| Torus Therapeutics | , | Changed name to Generation Bio, Nov 2017 |
| KMT Hepatech | , | Acquired by PhoenixBio, Dec 2017 |
| Discovery Genomics | , | Acquired by Immusoft, Mar 2016 |
| Rxbiologics | Cambridge, UK | Antibody Discovery |
| Invicro | , | Part of Perceptive Jan 2025; Acquired by Konica Minolta, Sep 2017 |
| Attralus | Naples, FL | Amyloidosis Treatments |
| , | Acquired by Eagle Pharmaceuticals, Jun 2022, $100M | |
| K2 Therapeutics | , | Moved from Boston to San Diego, renamed Cidara Therapeutics Jun 2014 |
| Laviana Pharma | Jiangyan, China | Chemical production and services, Formulation Services |
| Translate Bio | , | Acquired by Sanofi, Sep 2021, $3.2B; fka RaNa Therapeutics |
| Genome Explorations | , | Acquired by Tesis Biosciences, Feb 2022 |
| Caprion Biosciences | , | Renamed CellCarta, Feb 2021 |
| , | Sold off assets, seems effecively defunct, Dec 2025 | |
| Nexus Biosystems | , | Acquired by Brooks, Jul 2011 |
| Desktop Genetics | , | Website gone May 2020 - Jan 2021 |
| Celllect | , | Merged with Quoin Pharmaceuticals, Mar 2021, took name |
| Incuron | , | Website down Dec 2022 - Apr 2023 |
| Tella | , | Website down May 2023 - Dec 2023 |
| Epygen Biotech | Arvada, CO | Biosimilars |
| Discovery Labs | , | Changed name to Windtree Therapeutics, Apr 2016 |
| GliaMed | , | Website copyright 2009, seems defunct |
| Science 37 | Morrisville, NC | CRO Recruitment |
| Capture Pharmaceuticals | , | Company founded 2009, never got into clinic as of 2020. No employees |
| Sterling Industries | Concord, ON | Medical Device Contract Manufacturing & Development |
| RegeneraTEch | , | Renamed Regencor |
| , | No news 2020 - Dec 2025 | |
| Motive Health | Scottsdale, AZ | Muscle Stimulation Device |
| LinCor Biosciences | , | Renamed Cornea Biosciences |
| Exalpha Biologicals | , | Acquired by LifeSpan Biosciences, Jul 2019 |
| Faron Pharmaceuticals | Turku, Finland | Biologics |
| Advaita | Ann Arbor, MI | Bioinformatics software |
| Flash Therapeutics | , | Renamed Flash Biosolutions, Oct 2024 |
| Valneva | Saint-Herblain, France | Vaccines, Antibodies and Cell Lines |
| ENDRA Life Sciences | Ann Arbor, MI | Ultrasonic Liver Disease Diagnostic |
| Adolor | , | Acquired by Cubist, Oct 2011, $415M |
| Pacgen Biopharmaceuticals Corporation | , | Renamed Pacgen Life Science Corp. |
| Quaero Life Science | Jiaxing, China | Analyzers, Diagnostic Products |
| Magic Hat Consulting | Fort Washington, PA | Boutique consulting firm partners with life science companies to optimize operations |
| Lundbeck | Valby, Denmark | Small Molecules, Specializing in psychiatric/neuro |
| Octoplus | , | Acquired by Dr. Reddy's, 2013, $36M |
| ARSI Canada | Mississauga, ON | Custom synthesis, analytical services, and drug development |
| Snapdragon Chemistry | , | Acquired by Cambrex, Nov 2022 |
| SCILEX | Palo Alto, CA | Transdermal Drug Delivery, 505(b)(2) |
| Mesoblast | Melbourne, Australia | Regenerative Medicine |
| NeuroNano Pharma | , | Gone 2018 |
| Alerion | , | Website down Aug 2020 - Feb 2021; No info on location, Jan 2019 |
| Intellirod Spine | , | Sold Assets late 2020 |
| Pfenex | , | Acquired by Ligand, Oct 2020, $437.5M + $78M milestone; Spun out of Dow Chemical 2009 |
| Camargo Pharmaceutical Services | , | Acquired by Premier Research, May 2021 |
| Arvelle Therapeutics | , | Acquired by Angelini Pharma, Jan 2021 |
| , | Website down Jan 2026 - May 2026 | |
| Sanofi-Aventis | , | Renamed Sanofi May 2011; Formed in 2004 when Sanofi-Synthelabo acquired Aventis |
| Matrigen | , | Merged with PRIZM Pharmaceuticals, Jul 1998; Sold to The Tissue Repair Company, Dec 2004 |
| Spinal Dynamics | , | Acquired by Medtronic, Jun 2002, $270M |
| Inex Innovations Exchange | , | Merged with Nova Satra, Aug 2019 to become Inex Innovate |
| InteguRx | , | Website taken over, Dec 2023 |
| Viragen | , | Liquidated Oct 2007 |
| Chordia Therapeutics | Fujisawa, Japan | Oncology Treatments |
| NewGen Therapeutics | , | Website gone May 2019 - Dec 2020 |
| Predictus BioSciences | , | Not registered in MA, 2018 - Feb 2025; sole employee is professor |
| Avalanche Biotechnologies | , | Merged with Annapurna, Feb 2016, Renamed Adverum Biotechnologies |
| Bioconvergence | , | Rebranded as Singota Solutions, Jul 2016 |
| Coyote Bioscience | Beijing, China | Molecular Diagnostics |
| Alaris Medical | , | Acquired by Cardinal Health, May 2004 |
| Grifols | Clayton, NC | Biologics |
| , | Renamed Novakand Pharma, Sep 2025 | |
| GPC Biotech | , | Acquired by Agennix, Nov 2009 |
| Alta Biomed | Carlsbad, CA | Medical Device Coatings |
| Genekam Biotechnology | Duisburg, Germany | PCR kits, cells, lab products, flow cytometry reagents |
| , | Website down Apr 2026; No business info Aug 2025 - Sep 2025 | |
| HemoSonics | Durham, NC | Point-of-care diagnostic platform |
| Modalis Therapeutics | Waltham, MA | Genome Editing Tools for Therapeutic Discovery |
| Respirix | , | Renamed Cardiospire, Oct 2022 |
| DUSA Pharmaceuticals | , | Part of Sun Pharmaceuticals |
| Denovium | , | Acquired by AbSci, Jan 2021 |
| Fidelta | , | sold by Galapagos to Selvita, Nov 2020, $37M |
| MicroConstants | , | Acquired by BioAgilytix, Aug 2021 |
| IndiPharm | , | Acquired by private equity to be relaunched as InClinica |
| Facet Life Sciences | Phoenixville, PA | Life Science Consulting |
| , | Acquired by Syner-G BioPharma Group | |
| VeroPharm | , | Acquired by Abbott, Dec 2014, $495M |
| Nexell Therapeutics | , | Liquidated Oct 2002 |
| Sigilon Therapeutics | , | Acquired by Eli Lilly, Aug 2023, $35M + $273.4M milestones |
| Coave Therapeutics | Paris, France | Gene Therapy in Ophthalmology |
| Zevacor Molecular | , | Acquired by Curium, Mar 2020 |
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Morrisville, NC | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| Ken Block Consulting | Paris, France | Regulatory Consulting for Medical Device Companies |
| Zor Pharmaceuticals | , | Website gone, May 2015 |
| XACT Robotics | Caesarea, Israel | Robotic device for percutaneous radiology procedures |
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Canton, MA | Solvias is a global CRO, providing CMC analytical services to pharma and biotech for small molecules, CGT and biologics across all stages of drug development. |
| ClinicalTrialsTeam | Madrid, Spain | Clinical Monitoring |
| OSO Biopharmaceuticals | , | Acquired by AMRI, Jul 2014 |
| Arialys Therapeutics | La Jolla, CA | Therapies for autoimmune neuropsychiatric diseases |
| Ascend Advanced Therapies | Planegg, Germany | Gene Therapy CDMO |
| , | Company gone Nov 2023, website taken by a game | |
| Sparta Biodiscovery | London, UK | Nanoformulations |
| Z-Medica | , | Acquired by Teleflex, Jan 2021, $500M + $25M milestones |
| Regulaxis | , | No news 2020-2024 |
| Ocean Ridge Biosciences | , | Acquired by Frontage, Apr 2021 |
| Cryno | , | Website down Jan 2023 - Jul 2023 |
| BiOptix | , | Sold for cryptocurrency ticker use |
| Plureon | , | Website gone, one employee after 17 years |
| Linical | Stuart, FL | Clinical Research |
| Intranasal Therapeutics | , | Changed name to Ikano Therapeutics 2009 |
| Scandinavian Development Services | , | Website down Dec 2023 - May 2024 |
| Precision Therapeutics (1) | , | Changed name to Helomics, Nov 2014 |
| Smart Pharma Consulting | West Chester, PA | Pharma Consulting |
| , | Acquired by J&J, Mar 2024, $2B; Bought by joint venture of 4 Chinese pharma companies | |
| Ipca Laboratories | Mumbai, India | APIs |
| Ottobock | Vienna, Austria | Prosthetics |
| Integer | Brooklyn Park, MN | Medical & Surgical Devices |
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Hesperia, CA | Grace | Highly efficient chromatography resins and superparamagnetic silicas for purification and separation that deliver precision, specificity, recovery, and reproducibility. Available in a wide range of pore diameters, particle sizes, and chromatography phases. |
| Talima Therapeutics | , | Closed 2011 |
| Novo Nordisk | Beijing, China | Inflammation Research |
| BTB Therapeutics | Kyoto, Japan | Non-opioid therapies and novel RNA splicing modifiers |
| CEVEC Pharmaceuticals | , | Acquired by Cytiva, Oct 2022 |
| Virtuoso Surgical | Nashville, TN | Endoscopic Surgical Robot |
| Beta-Pro | , | Now Triangle Research Labs |
| , | Website down Sep 2025 - Feb 2026 | |
| Genoscience Pharma | Marseille, France | Small Molecules Targeting Lysosomes |
| Depixus | Courbevoie, France | Platform technology for the fast, accurate, and inexpensive extraction of multiomic information from DNA, RNA, and protein |
| Accell Clinical Research | Warrenton, VA | Clinical Research |
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Zagreb, Croatia | A CRO built to deliver faster Clinical Trials. Optimapharm is a global CRO with integrated therapeutic platforms and 2x NA/EU reach |
| OrthAlign | Irvine, CA | Inertial Navigation systems for joint replacement surgery |
| Journey Colab | , | Shut down Jan 2025 |
| Bionovica | , | Website gone Dec 2022 |
| CytoMol (2) | , | SF-based, Looks gone |
| Photon Biosciences | Spokane Valley, WA | Diagnostic Platform |
| Partillion Bioscience | Los Angeles, CA | Functional Single-cell Biology Reagent Platform |
| Thrombotargets | , | Website down May 2021 - Jan 2022 |
| Cerebain Biotech | , | Website down Dec 2022 - Apr 2023 |
| Telix Pharmaceuticals | Geneva, Switzerland | Radio immunotherapy |
| Endotarget | , | Website down Dec 2024 - May 2025 |
| JHP Pharma | , | Bought by Par Pharmaceuticals |
| Howfond | , | Website gone, Jul 2015 |
| Analytical Biological Services | New Castle, DE | Custom Bioreagents |
| AcuMedical | , | Website down, Founder gone Mar 2021 |
| Biosilta | , | Website gone, Feb 2017, Presumed Defunct |
| Proliant Biologicals | Ankeny, IA | The world's largest manufacturer of animal-derived proteins, producing a range of bovine serum albumin (BSA) offerings and animal extracts. |
| Recipharm | Wasserburg, Germany | Contract development and manufacturing partner to the pharmaceutical and biopharmaceutical industries. |
| Medivector | , | Gone late 2018 |
| American Bionostica | , | Acquired by Ott Scientific, May 2021 |
| Schrodinger | San Diego, CA | Computation Drug Discovery Platform |
| Frequency Therapeutics | , | Merged with Korro Bio, Nov 2023 |
| Rho | Durham, NC | Clinical Research |
| PHASTAR | London, UK | Contract statistics, programming and data management |
| 3Brain | Freienbach, Switzerland | Cell-electronic interface for deep access of organoids and tissues |
| PNA Innovations | , | Believed to have been folded into TruCode Gene Repair |
| Neogap Therapeutics | Stockholm, Sweden | Personalized Tumor Trained Lymphocytes |
| Polysciences | Warrington, PA | Reagents, Polymers, Coatings |
| Cellinfinity Bio | New Haven, CT | Cell Therapy Technology |
| Sumitomo Pharma Oncology | , | part of Sumitomo; aka SDP Oncology |
| Valo Health | New York, NY | Drug Discovery & Development Engine |
| , | Website down May 2025 - Dec 2025 | |
| OmniBiome Therapeutics | , | Gone 2014? |
| RHEINCELL Therapeutics | , | Acquired by Catalent, Jun 2021 |
| Pfizer | Shanghai, China | Small Molecules, Biologics, Vaccines |
| Organic Vaccines | , | Website down Mar 2024 - Jul 2024 |
| Merck KGaA | Singapore, Singapore | Small Molecules, Purification Equipment, etc. |
| mdRNA | , | Merged with Cequent Pharmaceuticals, became Marina Biotech 2010 |
| Acepodia | Taipei City, Taiwan | Antibody-Cell Conjugation Therapy |
| AcroViz | Taipei City, Taiwan | Neuro-Imaging |
| ACT Genomics | Taipei, Taiwan | Cancer Genomic Profiling |
| Agilent | Taoyuan, Taiwan | High-Throughput Screening Equipment, Imaging instruments |
| AltruBio | Taipei, Taiwan | Antibody Therapeutics |
| Amaran Biotech | Zhubei , Taiwan | Contract Manufacturing - Biologics |
| Anbogen Therapeutics | Taipei, Taiwan | Precision Oncology |
| Andros Pharmaceutical | Zhubei, Taiwan | Novel Drug Delivery Platforms |
| AnHorn Medicines | New Taipei, Taiwan | Targeted Protein Degradation |
| AnnJi Pharmaceutical | Taipei City, Taiwan | Small Molecules for Dermatology & neurology |
| AP Biosciences | Taipei, Taiwan | Bispecific Antibodies |
| Bora CDMO | Tainan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora CDMO | Zhunan, Taiwan | Bora Pharmaceuticals is a full-service CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Bora Pharmaceuticals | Taipei, Taiwan | CDMO providing development and manufacturing solutions for a wide range of dosage forms, from clinical to commercial supply. |
| Caliway Biopharmaceuticals | New Taipei City, Taiwan | Novel drugs for obesity and anti-aging cosmedicine products |
| Dasher Neuroscience | Taipei, Taiwan | Novel drugs for neuropsychological and neurological diseases |
| EAG Laboratories | Hsinchu, Taiwan | Analytical & Synthesis Services |
| EirGenix | New Taipei City, Taiwan | Biologics Contract Development & Manufacturing |
| Energenesis Biomedical | Taipei, Taiwan | Small Molecules |
| Eusol Biotech | Taipei, Taiwan | Biologics |
| Foresee Pharmaceuticals | Taipei, Taiwan | Drug Delivery tech |
| Formosa Pharmaceuticals | Taipei, Taiwan | Activus Pure Nanoparticle Technology |
| General Biologicals Corporation | Hsinchu, Taiwan | Diagnostics |
| GeneReach Biotechnology | Taichung , Taiwan | Reagents & Instruments |
| GenomeFrontier Therapeutics | New Taipei City, Taiwan | Gene Therapy Delivery |
| Health Ever Bio-Tech | Taipei, Taiwan | Botanical Drugs |
| Holy Stone Healthcare | Taipei, Taiwan | Small Molecules |
| Locus Cell | New Taipei City, Taiwan | CAR T |
| Lumosa Therapeutics | Taipei, Taiwan | Small Molecules |
| Medigen (2) | Taipei, Taiwan | Therapies for liver diseases and cancers |
| Medigen Vaccine Biologics | Taipei, Taiwan | Vaccines, Biologics |
| Micronbrane Medical | Zhubei, Taiwan | Fractionation Technology for Clinical microbiology |
| Mycenax Biotech | Zhubei, Taiwan | CDMO, Biosimilars |
| Novotech | Taipei, Taiwan | Clinical Research |
| OBI Pharma | Taipei, Taiwan | Biologics |
| Oneness Biotech | Taipei City, Taiwan | Small Molecules, Antibodies |
| Panion & BF Biotech | Taipei City, Taiwan | Diagnostics, Small Molecules |
| Papivax | Taipei , Taiwan | HPV Vaccines |
| PELL BMT | Taipei City, Taiwan | Cell Processing Technology |
| Pharmadax | New Taipei City, Taiwan | Generics |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (Qualitix/NKSP) is a full service Clinical Trial Services division, with a Bioanalysis lab for clinical trial sample analysis. |
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Taipei, Taiwan | QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. QPS Taiwan (CTPS) is a full service Discovery, Preclinical, Toxicology and Pharmacology laboratory. |
| ScinoPharm Taiwan | Tainan, Taiwan | API Manufacturing & Services |
| SHL Medical | Taoyuan , Taiwan | Medical Device assembly, labeling, packaging |
| Syncell | Taipei City, Taiwan | Spatial Proteomics Technology |
| SynCore Biotechnology | I-Lan, Taiwan | Small Molecules, Diagnostics |
| Taiwan Liposome Company | Taipei, Taiwan | LipAD lipid-assembled delivery system |
| Taiwan Resonant Waves Research | Taipei, Taiwan | Nerve Stimulation Devices |
| TaiwanJ Pharmaceuticals | Zhubei, Taiwan | Small Molecules for Unmet Needs |
| TSH Biopharm | Taipei, Taiwan | Bringing Therapies to Asian Market |
| Veristat | Taipei, Taiwan | Full service clinical trial execution, regulatory consulting, and strategic planning to rapidly advance development, approval, and commercialization of your revolutionary therapies around the globe. |
| Wellell | New Taipei City, Taiwan | Respiratory therapy & wound management |
| Worldwide Clinical Trials | Taipei, Taiwan | Worldwide Clinical Trials provides clinical research services to biotech/pharmaceutical companies. |
| Xgene Pharmaceutical | Taipei, Taiwan | Small Molecule Dual-Targeting Conjugates for Pain |
| Zai Lab | Taipei, Taiwan | Small Molecules |